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T82456 |
EPO mimetic peptide-1
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EMP-1 |
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EPO Mimetic Peptide-1 (EMP-1) is a 20 amino acid peptide that promotes cell proliferation, modulates the cell cycle, and stimulates reticulocyte production in vivo [1]. |
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T82683 |
Connexin mimetic peptide 40GAP27
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Connexin mimetic peptide 40GAP27, corresponding to the GAP27 domain of the second extracellular loop of the dominant vascular connexin (Cx40), designated as 40Gap27, is a biologically active peptide utilized to study the... |
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T82684 |
Connexin mimetic peptide 40,37GAP26
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Connexin mimetic peptide 40,37GAP26, a biologically active peptide, matches the GAP26 domain of the extracellular loop of major vascular connexins Cx37 and Cx40, referred to as 37,40Gap26 based on Cx homology. It has bee... |
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T16276 |
NBD-556
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HIV Protease
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NBD-556 is a small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding. |
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T11282 |
FGTI-2734
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Transferase
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T2099 |
ABT-737
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Mitophagy
,
BCL
,
Autophagy
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ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w (EC50s: 78.7/30.3/197.8 nM). |
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T8655 |
SR-717
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STING
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SR-717 is a cGAMP analog, a non-nucleoside STING agonist that induces a "closed" activation conformation of STING. SR-717 has antitumor activity and promotes activation of immune cells and cross-presentation of antigens. |
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T40612 |
Manganese(salen) chloride
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EUK-8 |
Others
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Manganese(salen) chloride (EUK-8) (EUK-8) is a superoxide dismutase and catalase mimetic. Manganese(salen) chloride (EUK-8) is an antioxidant with oxyradical scavenging properties. Manganese(salen) chloride ameliorates a... |
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T6275 |
Obatoclax Mesylate
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Obatoclax,GX15-070 |
BCL
,
Parasite
,
Autophagy
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Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3. |
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T6495 |
EUK-134
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EUK 134 |
Beta Amyloid
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EUK-134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril. |
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T6543 |
Indoximod
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NLG-8189,Indoximod (NLG-8189）,1-Methyl-D-tryptophan |
Indoleamine 2,3-Dioxygenase (IDO)
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Indoximod (Indoximod (NLG-8189)) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan... |
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T6763 |
Xevinapant
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ARRY-334543,SM-406,AT406,Debio-1143 |
IAP
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Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, ... |
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T0825 |
Ebselen
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SPI-1005,PZ-51,CCG-39161 |
Phosphatase
,
Virus Protease
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Calcium Channel
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COX
,
HIV Protease
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Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced b... |
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T3299 |
Xevinapant hydrochloride
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AT-406 HCl,SM-406 |
Apoptosis
,
IAP
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Xevinapant hydrochloride (AT-406 HCl) , an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.... |
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T12857 |
SC-52012
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Others
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SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation. |
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T19345 |
GP2-114
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Others
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GP2-114 is a catecholamine exercise mimetic that can be used to study coronary artery disease (CAD). |
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T21839L |
10Panx Acetate
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10Panx Acetate(955091-53-9 Free base) |
Others
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10Panx Acetate is a mimetic inhibitory peptide that readily and reversibly inhibits the panx1 currents. |
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T37596 |
Terevalefim
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c-Met/HGFR
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Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor. |
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T2080 |
LCL161
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IAP
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LCL161, a SMAC mimetic, effectivity binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP). |
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T16809 |
Rupintrivir
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AG-7088,AG7088,Rupintrivirvr |
Virus Protease
,
Antiviral
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Rupintrivirvr (AG7088) is a selective rhinovirus (HRV) 3C cysteine protease mimetic peptide inhibitor with antiviral and immunomodulatory activities.Rupintrivirvr inhibits the replication of EV71 and EV-D68, and may be u... |
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T24088 |
GGTI-2133
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GGTI2133,GGTI 2133 |
Transferase
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GGTI-2133 is a potent mimetic peptidyl geranylgeranyltransferase type I inhibitor (GGTase I) with an IC50 value of 38 nM.GGTI-2133 inhibits the invasion of inflammatory cells into the airways in experimental asthma in mi... |
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T7568 |
LM22A-4
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Trk receptor
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LM22A-4 is a brain-derived neurotrophic factor (BDNF) mimetic and agonist of the receptor tropomyosin-related kinase B (TrkB; IC50 : 47 nM in a fluorescence anisotropy assay) |
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T5360 |
Eprotirome
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KB2115 |
Thyroid hormone receptor(THR)
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Eprotirome (KB2115), a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist. |
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T14133 |
AEOL-10150 pentachloride
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Others
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AEOL-10150 pentachloride is a metalloporphyrin catalytic antioxidant. AEOL-10150 pentachloride also is a superoxide dismutase mimetic. Which protects lungs from radiation-induced injury. |
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T5192 |
Gap 26
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Gap Junction Protein
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Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker. |
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T19428 |
Mito-TEMPO
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Reactive Oxygen Species
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Mitochondrial Metabolism
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Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO scavenges superoxide and alkyl radicals and prevents mitochondrial oxidation, necrosis and apoptosis. |
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T27773L |
L-739750 2HCl
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L-739750 2HCl(160141-08-2 Free base) |
Transferase
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L-739750 2HCl is a potent inhibitor of peptidomimetic farnesyltransferase, a novel pseudopeptide mimetic with potential anticancer activity. |
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T67733 |
BT44
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Others
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BT44 is a novel, second-generation glial cell line_x0002_derived neurotropic factor mimetic with improved biological activity and is a lead compound for the treatment of neurodegenerative disorders. |
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T8639 |
Phenibut (hydrochloride)
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3-Amino-4-phenylbutyric acid hydrochloride |
GABA Receptor
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Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates dopamine receptor... |
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T11438 |
GNE-1858
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Others
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MAPK
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T74398 |
DATPT
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Reactive Oxygen Species
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Antibacterial
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DATPT is a small molecule 12WLVSKF17 peptide mimetic molecule.DATPT inhibits SNX9-p47phox interactions and inhibits the production of reactive oxygen species and inflammatory cytokines.DATPT has anti-inflammatory and ant... |
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T29067 |
Upacicalcet
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PLS-240,SK-1403,AJT-240 |
Calcium Channel
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Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-s... |
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T34281 |
Relamorelin
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BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131 |
GHSR
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Relamorelin (RM-131), a selective and potent growth hormone-releasing peptide/growth hormone secretagogue receptor (GHSR) agonist, is a potent growth hormone-releasing peptide mimetic with a high affinity for the GHS-1a ... |
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T29067L |
Upacicalcet HCl
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Upacicalcet HCl(1333218-50-0 Free base) |
CaSR
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Upacicalcet HCl is an intravesical calcium mimetic that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on calcium-sensitive receptors in parathyroid cell membranes, thereby lowering PTH levels ... |
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TP1565L1 |
Foxy-5 Ammonium Salt
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Foxy-5 Ammonium Salt（881188-51-8 Free base) |
Wnt/beta-catenin
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Foxy-5 Ammonium Salt is a WNT5A agonist, a mimetic peptide of WNT5A, a non-classical member of the Wnt family.Foxy-5 Ammonium Salt triggers cytoplasmic free calcium signaling without affecting β-catenin activation and in... |
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T38164 |
MnTBAP chloride
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Mn(III)TBAP |
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MnTBAP chloride (Mn(III)TBAP) is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger that reduces the doubling time of SOD-E. coli by a factor of 2. MnTBAP chloride exhibits anti-inflammatory ... |
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T33734 |
NS 11
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NS-11,NS11 |
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NS 11 is an RGD-nonpeptidic mimetic. |
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T34556 |
SC 55858
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SC-55858,SC55858 |
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SC 55858 is a superoxide dismutase mimetic. |
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T29722 |
AGN 191976
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AGN 191976 is a novel thromboxane A2-mimetic. |
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T25118 |
Avasopasem manganese
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Avasopasem manganese is a drug candidate of superoxide dismutase mimetic. |
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T7348 |
Imisopasem manganese
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M40403 |
Others
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Imisopasem manganese (M40403) is a manganese superoxide MnSOD non-peptidyl mimetic. |
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T25847 |
NAEPA
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NAEPA, an LPA mimetic, is a selective agonist of the lysophosphatidic acid-1 (LPA1) receptor. |
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T34417 |
RS 93427-007
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RS-93427-007,RS93427-007 |
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RS-93427-007 is an orally active stable mimetic agent of prostacyclin for the study of mechanisms of atherogenesis. |
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T26242 |
SW IV-52
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SW-IV-52,SW IV52,SW IV 52,SWIV52 |
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SW IV-52 is an XIAP-inhibitor that acts as a second mitochondria-derived activator of caspases (SMAC) mimetic. |
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T30998 |
COG1410
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COG-1410,COG 1410 |
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COG-1410 is an apolipoprotein E (apoE) peptide mimetic. |
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T17000 |
Tavilermide
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MIM-D3 |
Trk receptor
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Tavilermide is a selective and partial agonist of TrkA or a nerve growth factor mimetic. |
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T70457 |
MDL-73669
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MDL-73669 is a macrocyclic HIV-protease inhibitor that contains a difluorostatone peptide mimetic. |
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T27373 |
FR-181157
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FR-181157 Free Base |
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FR-181157, a novel prostaglandin (PG) mimetic, shows high potency and agonist efficacy at the IP receptor and has good bioavailability. |
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TP1565 |
Foxy-5
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Foxy-5 is a wnt5a peptide mimetic |
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T36851 |
Peptide5
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Connexin43 mimetic peptide. Reduces swelling, astrogliosis, neuroinflammation and neuronal cell death following spinal cord injury ex vivo and in vivo. Exhibits analgesic effects in models of neuropathic pain.
O'Carroll ... |
