| T4085 |
Paris saponin VII
|
Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII |
Apoptosis
,
BCL
,
Others
,
PARP
,
p38 MAPK
,
Akt
,
Caspase
,
P-gp
,
Autophagy
|
|
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation. |
| TN2289 |
Licorice-saponin H2
|
Licoricesaponin H2 |
Others
|
|
Licorice-saponin H2 (Licoricesaponin H2) is a natural product |
| T3909 |
Pulsatilla saponin D
|
Hederacolchiside A,SB365 |
Apoptosis
,
Others
|
|
Pulsatilla saponin D (Hederacolchiside A) has exhibited potential beneficial effects as a chemopreventive agent for critical health conditions including cancer, and it inhibits cell growth via cell cycle arrest and apopt... |
| TN2119 |
Pulsatilla saponin H
|
|
Others
|
|
Pulsatilla saponin H is a natural product isolated from the Roots of Pulsatilla koreana. |
| TN2329 |
Zingiberen newsaponin
|
Zingiberensis saponin I |
PARP
,
PAFR
,
Caspase
|
|
Zingiberen newsaponin is a steroidal saponin from Dioscorea zingiberensis. |
| T6654 |
Saponins
|
Sapogenins Glycosides,Saponin |
Others
|
|
Saponins (Sapogenins Glycosides) are a mixture of triterpene and steroid saponins isolated from medicinal plants such as Aesculus hippocastanum L., Hedera helix L. and Ruscus aculeatus L., which are claimed to be effecti... |
| T3894 |
Polyphyllin II
|
Chonglou Saponin II |
Apoptosis
,
Others
|
|
Polyphyllin II (Chonglou Saponin II) has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects. |
| TN2443 |
Chikusetsusaponin Ib
|
Chikusetsu saponin Ib |
AChE
|
|
Chikusetsusaponin Ib (Chikusetsu saponin Ib) is an inhibitor of AChE and can be used in studies about anti-Alzheimer's diseases. |
| T41124 |
Kizuta saponin K11
|
|
|
|
Kizuta saponin K11 is a saponin derived from Kalopanax pictum var. maximowiczii leaves, which is a widely used Korean medicinal plant. |
| T2698 |
Asperosaponin VI
|
Akebia saponin D,Asperosaponin Ⅵ |
Apoptosis
,
Others
,
Caspase
|
|
Asperosaponin VI (Akebia saponin D) , the most abundant constituent of the rhizome of Dipsacus asper, has been used for the treatment of lower back pain, traumatic hematoma and bone fractures. |
| TN1510 |
Clematomandshurica saponin B
|
|
COX
|
|
Clematomandshurica saponin B shows significant inhibitory activity on cyclooxygenase-2 (IC50 = 2.58 microM). |
| T6473 |
Dioscin
|
CCRIS 4123,Collettiside III,Saponin |
Apoptosis
,
Autophagy
|
|
Dioscin (Collettiside III) is a saponin with antitumor activities. |
| T3771 |
Methyl protodioscin
|
Smilax saponin B,NSC-698790 |
Apoptosis
|
|
Methyl protodioscin (Smilax saponin B) potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced apoptotic process in h... |
| T3910 |
Pulchinenoside C
|
Anemoside B4,Chinensioside A,Pulchinenoside B4,Pulsatilla saponin B4 |
IL Receptor
|
|
Pulchinenoside C (Anemoside B4) is an abundant triterpenoid saponin isolated from P. chinensis and exerts anti-inflammatory and antioxidant effects. |
| TN1509 |
Clematomandshurica saponin C
|
Clematiunicinoside E |
Others
|
|
Clematiunicinoside E is a natural product from Clematis uncinata. |
| T5794 |
Saponin C from Liriope muscari
|
Liriope muscari baily Saponins C |
|
|
Saponin C from Liriope muscari can be extracted from Liriope muscari, family Liliaceae. |
| T83395 |
24-Hydroxy-licorice-saponin A3
|
|
|
|
24-Hydroxy-licorice-saponin A3, an oleanane-type triterpene saponin (OTS), can be isolated from Glycyrrhiza uralensis [1]. |
| TN2118 |
Lup-20(29)-en-28-oic acid
|
Pulsatilla saponin D |
ERK
,
mTOR
,
Autophagy
|
|
Lup-20(29)-en-28-oic acid exhibits anticancer activities in various cancer types, it Inhibits autophagic flux and synergistically enhances the anticancer activity of chemotherapeutic agents against HeLa cells.Pulsatilla ... |
| TP2223 |
Beesioside Q
|
|
Others
|
|
Beesioside Q is a natural product extracted from the rhizome of Beesia calthaefolia (Maxim.) Ulbr. |
| T5797 |
Raddeanoside R8
|
|
Others
|
|
Raddeanoside R8 is a natural product from Anemone raddeana Regel. |
| T3S1265 |
Liriopesides B
|
Nolinospiroside F |
Others
|
|
Liriopesides B (Nolinospiroside F) exhibited potential anticancer activity against human ovarian cancer A2780 cells. |
| T3858 |
Macranthoidin A
|
|
Others
|
|
Macranthoidin A has anti-inflammation activity. |
| TN1721 |
Gypenoside L
|
|
ERK
,
p38 MAPK
,
Calcium Channel
,
NF-κB
,
ROS
|
|
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small cell lung carcinoma A549 cell inhibitory a... |
| T2961 |
Notoginsenoside R1
|
Sanqi glucoside R1,Sanchinoside R1 |
Apoptosis
,
ERK
,
Beta Amyloid
|
|
Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties. |
| T4S1312 |
Gypsogenin-3-O-glucuronide
|
Methyl gypsogenin 3-O-beta-D-glucuronopy |
Others
|
|
1. Gypsogenin-3-O-glucuronide (Methyl gypsogenin 3-O-beta-D-glucuronopy) shows inhibitory activity toward pancreatic lipase with IC5 value of .29 mM, and the free carboxylic acid groups in position 28 within its chemical... |
| T2S2295 |
Timosaponin A1
|
|
Others
|
|
Timosaponin A1 is a coprostane type steroidal saponin found in Rhizoma Anemarrhenae. |
| T3912 |
Saikosaponin B1
|
|
Others
|
|
Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro. |
| TN1383 |
Timosaponin B III
|
Anemarsaponin BIII |
Others
,
Platelet aggregation
|
|
Timosaponin B III (Anemarsaponin BIII) is a bioactive steroidal saponin isolated from Anemarrhena asphodeloides Bge. Timosaponin B III possesses anti-inflammatory, anti-platelet aggregative and anti-depressive effects. |
| T75675 |
Nepasaikosaponin K
|
|
Antiviral
|
|
Nepasaikosaponin K is a small molecule compound isolated from Chaikosaponin root with anti-influenza and antiviral activity and can be used in the study of viral infections. |
| T8209 |
Saikosaponin b3
|
|
Others
|
|
Saikosaponin B3 shows some analgesic effect. |
| TN1600 |
Eclalbasaponin I
|
|
Others
|
|
Eclalbasaponin I has anti-oxidative, and antitumor activities, it reduces oxidative stress-induced neural cell death by autophagy activation, it can dose-dependently inhibit the proliferation of hepatoma cell smmc-7721 w... |
| T2768 |
Saikosaponin A
|
|
NF-κB
,
Antibacterial
,
Liver X Receptor
|
|
Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-bacterial activities. It can effectively attenuate neuropath... |
| T3913 |
Saikosaponin D
|
|
Estrogen Receptor/ERR
,
NF-κB
,
Antibacterial
,
STAT
|
|
Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity. |
| TN1866 |
Licoricesaponin G2
|
|
|
|
Licoricesaponin G2 is a pentacyclic triterpenoid derived from Glycyrrhiza aspera, which can be used to differentiate crude liquorice from honey-processed liquorice. |
| TN2230 |
Soyasaponin Ba
|
|
Others
|
|
Soyasaponin Ba may represent viable candidates for effective vaccine adjuvants due to their higher and lower or non-haemolytic effects.Soyasaponins Ab and Bb prevent scopolamine-induced memory impairment in mice without ... |
| T3S0601 |
Buddlejasaponin IVb
|
Saikosaponin 1b |
Others
|
|
1. Buddlejasaponin IVb (Saikosaponin 1b)(200 uM) can shorten thrombin time (TT) by 20.6 %, suggests that it has hemostasis efficacy. |
| T3S0687 |
Ecliptasaponin D
|
|
Others
|
|
Ecliptasaponin D is a natural product for research related to life sciences. The catalog number is T3S0687 and the CAS number is 206756-04-9. |
| T3863 |
Chikusetsusaponin IVa
|
Calenduloside F |
AMPK
|
|
Chikusetsusaponin IVa (Calenduloside F) is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR4 mediated calcium and PKC pathways, may be developed into a new potential for therapeutic agent used... |
| TN1432 |
Bacopasaponin C
|
|
Anti-infection
,
GABA Receptor
,
NMDAR
|
|
Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property. |
| TN1149 |
6''-O-acetylsaikosaponin A
|
|
Others
|
|
6''-O-acetylsaikosaponin A is an acetyl saikosaponin isolated from the roots of Bupleurum chinense. Itshows some osteoclast-inhibiting activities |
| T8174 |
Saikosaponin F
|
|
Others
|
|
Saikosaponin F is a natural compound found in Bupleurum (B.) falcatum L. |
| T3826 |
Polygalasaponin F
|
|
NF-κB
,
TLR
,
Akt
,
PI3K
|
|
Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po... |
| T7030 |
Anemarsaponin B
|
|
p38 MAPK
,
NF-κB
,
MEK
,
COX
,
NO Synthase
|
|
Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B c... |
| TQ0036 |
Anemarrhenasaponin I
|
|
Others
|
|
Anemarrhenasaponin I shows the remarkable inhibiting effect on platelet aggregation. |
| T3S0335 |
Soyasaponin Bb
|
Soyasaponin I |
NF-κB
,
Caspase
|
|
1. Soyasaponin Bb (Soyasaponin I) can suppress Eca-976 cell growth, reverse effects on over expression of c-met, VEGF, and induce cell apoptosis through inhibiting HDAC1-NF-kappaB and activating PETEN and caspase-3 signa... |
| T2S0500 |
Ilexsaponin A
|
Ilexsaponin A1 |
Others
|
|
1. Ilexsaponin A (Ilexsaponin A1) shows protective effects on ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway. |
| T3394 |
Timosaponin BII
|
Prototimosaponin A III |
Beta Amyloid
,
Others
,
BACE
|
|
Timosaponin BII (Prototimosaponin A III) has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-regulation of BACE1 and reduced the... |
| T3810 |
Saikosaponin B2
|
|
Others
,
HCV Protease
|
|
Saikosaponin B2 acts on HCV E2 and inhibits infection by several genotypic strains and prevents binding of serum-derived HCV onto hepatoma cells. Saikosaponin B2 (5 μM) induces differentiation of B16 melanoma cells, with... |
| T3914 |
Saikosaponin C
|
|
Beta Amyloid
,
Caspase
|
|
Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation. |
| TN1140 |
Onjisaponin B
|
|
AMPK
,
mTOR
,
Autophagy
|
|
Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-synuclein, it may have potential therapeutic effects on Parki... |
