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Search Results for " factor-AT "

ターゲット

74

阻害剤

16

天然化合物

114

リコンビナントタンパク質

2

ライブラリー

カタログ番号 製品名 別名 ターゲット
T0947 Dexamethasone acetate Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471 Glucocorticoid Receptor , Mitophagy , IL Receptor , Annexin A , NOS , Antibacterial , Autophagy
Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexa...
T3469 PCI-27483 PCI27483 Others
PCI-27483 is an activated coagulation factor VIIa inhibitor with antithrombotic effects in a baboon model of arterial thrombosis. It also inhibits the growth of BxPC3 xenografts by 42% and 85% at doses of 60 and 90 mg/kg...
T1823 IOX2 IOX 2,JICL38 HIF/HIF Prolyl-Hydroxylase
IOX2 (IOX 2) is a selective inhibitor of the Hypoxia Inducible Factor (HIF) Prolyl-Hydroxylases (PHD); active in cells with the IC50 value of 21 nM for PHD2/ELGN-1 and no inhibition at FIH (20uM).
TP1820L Osteogenic Growth Peptide, OGP acetate Osteogenic Growth Peptide, OGP acetate(132996-61-3 free base) Others
Osteogenic Growth Peptide, OGP acetate is a short, naturally occurring 14-mer growth factor peptide found in serum at μM concentrations. Osteogenic growth peptide OGP is a key factor in the mechanism of the systemic oste...
T4567 Sulfaphenazole Plisulfan,Raziosulfa,Depocid,Depotsulfonamide P450 , Antibacterial
Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for CYP2C8/CYP2C18, respectively, and no activity at CYP1A1, CYP1...
T22833 H-9 dihydrochloride EGFR , 5-HT Receptor , PKA
H-9 dihydrochloride is a potent protein kinase (PKA) inhibitor.H-9 Dihydrochloride significantly reduces the excitatory response to 5-HT at low concentrations.H-9 Dihydrochloride affects pharyngeal activity.H-9 Dihydroch...
T12006 Metarrestin ML246 DNA/RNA Synthesis
Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase (...
T76810 Ganitumab AMG 479 IGF-1R
Ganitumab (AMG 479) is a highly potent monoclonal antibody to type 1 insulin-like growth factor receptor (IGF1R). Ganitumab is recognized to bind to IGF1R at low concentration with KD value of 0.22 nM. Ganitumab can inhi...
T22297 Clindamycin hydrochloride monohydrate Clindamycin alcoholate Antibiotic
Clindamycin hydrochloride monohydrate (Clindamycin alcoholate) is a protein synthesis inhibitor used orally, capable of diminishing virulence factor expression in Staphylococcus aureus at sub-minimum inhibitory concentra...
T14775 Bragsin2 6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one,Bragsin 2 Others
Bragsin2 (6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one) is a hydration-resistant cell penetrant, selective and non-competitive inhibitor of Afr guanine nucleotide exchange factor BRAG2 that inhibits Arf GTPase acti...
T38293 4-CPPC Others
4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).1It is selective for MIF-2 over MIF-1 (IC50= 450 μM). It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concen...
T31206 Darexaban YM 150,Darexaban, Tanexaban,YM150 Factor Xa
Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothrombin activity at the site of blood clot (thrombus) formati...
T16500 PF-3450074 PF-74 HIV Protease
PF-3450074 (PF-74) acts at an early stage of HIV-1 infection inhibits viral replication by directly competing with the binding of CPSF6 (nuclear host factors cleavage and polyadenylation specific factor 6) and NUP153 (nu...
T0983L DL-Penicillamine 3-Sulfanylvaline Antibiotic
DL-Penicillamine (3-Sulfanylvaline) is a chelating agent recommended for the removal of excess copper in patients with Wilson's disease. DL-Penicillamine is only found in individuals that have used or taken this drug. It...
T26968 CCT036477 CCT 036477,CCT-036477
CCT036477 is a selective inhibitor of wingless-type MMTV integration site family dependent transcription. CCT036477reduces the transcriptional activity of the T-cell factor and lymphoid enhancer factor transcription fact...
T29190 YM-75466 YM 466,YM-466,YM75466,YM 75466,YM-75466 Free
YM-75466 is a factor Xa inhibitor. YM-75466 did not prolong coagulation time even at the dose which exerted significant antithrombotic effects, while it decreased TAT level in plasma in a dose-dependent manner.
T35926 Bz-IEGR-pNA (acetate)
Bz-IEGR-pNA is a colorimetric substrate for Factor Xa.1 Factor Xa preferentially binds to and cleaves the Ile-Glu-Gly-Arg (IEGR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric d...
TP1820 Osteogenic Growth Peptide, OGP
Osteogenic Growth Peptide, OGP is a short, naturally occurring 14-mer growth factor peptide found in serum at μM concentrations. Osteogenic growth peptide OGP is a key factor in the mechanism of the systemic osteogenic r...
T37157 8(S)-HEPE
8(S)-HEPE is a monohydroxy fatty acid produced by lipoxygenase oxidation of EPA. It acts to promote hatching of barnacle eggs at 10 nM, although it is not clearly identified as the natural egg hatching factor.
T29072 UR-1505 UR1505,UR 1505
UR-1505 is a nuclear factor of activated T cells (NF-AT) inhibitor. UR-1505 acts by inhibiting T cell activation depending on T cell receptor signaling pathway. Furthermore, the antiproliferative effects of UR-1505 are n...
TP2048 α-Helical CRF(9-41) α-helical CRF 9-41
Corticotropin-releasing factor receptor antagonist (Ki values are 17, 5 and 0.97 at human CRF1, rat CRF2α and mouse CRF2β receptors respectively).
T25888 NSC-670224 NSC 670224
NSC-670224 is an inhibitor of histone deacetylases-6 (HDAC6) and nuclear factor-κB (NF-κB) activation blocker. It has been shown to be toxic to Saccharomyces cerevisiae at low micromolar concentrations, potentially acts ...
T35818 CAY10669
CAY10669 is an inhibitor of the histone acetyltransferase PCAF (p300/CREB-binding protein-associated factor; IC50 = 662 μM), displaying a 2-fold improvement in inhibitory potency over anacardic acid . At 30-60 μM, CAY106...
TP1361 S961 TFA (1083433-49-1 free base) S961 TFA
S961 TFA is A high affinity insulin receptor (IR) antagonist with IC50 for hir-a, hir-b and human insulin-like growth factor I receptor (higf-ir) at 0.048, 0.027 and 630 nM, respectively.
T27033 CKD-712 CKD 712,CKD712
CKD-712 is a nuclear factor NF-kappa B inhibitor. CKD-712 suppressed MMP-9, but not MMP-2 and other NF-κB-regulated proteins involved in cancer metastasis such as VEGF. CKD-712 induced cell cycle arrest at G2M phase by s...
T28015 Mequitamium iodide LG-30435,LG 30435,LG30435
Mequitamium iodide is a platelet activating factor (PAF) inhibitor. Mequitamium inhibits PAF-acether induced platelet aggregation and bronchoconstriction. Mequitamium is capable of inhibiting platelet-mediated effects of...
T36098 Isovaleryl-L-carnitine (chloride)
Isovaleryl-L-carnitine is a naturally occurring acylcarnitine that is formed via metabolic conversion of L-leucine. It increases survival and decreases apoptosis in hepatocyte growth factor-deprived murine C2.8 hepatocyt...
T76908 Anumigilimab
Anumigilimab (CSL-324) is a humanized IgG2a monoclonal antibody (mAb) targeting the human granulocyte colony-stimulating factor (G-CSF) receptor, utilized to elevate neutrophil counts at inflammation sites [1] [2].
T60722 Prohibitin ligand 1
Prohibitin ligand 1 (Compound 22i) is a cardioprotectant prohibitin ligand that exhibits in vitro cardioprotectant activities at nanomolar concentrations. Prohibitin ligand 1 induces the pro-survival factor STAT3 phospho...
T70170 Milvexian TFA
Milvexian, also known as BMS-986177 and JNJ-70033093, is a blood coagulation factor XIa inhibitor. Milvexian demonstrated good selectivity over plasma kallikreinKi = 44 nM (400-fold selective), and chymotrypsinKi = 35 ...
T35538 HPI-1 (hydrate) HPI-1 hydrate
HPI-1 (hydrate) is a Hedgehog (Hh) pathway inhibitor that suppresses signaling through Sonic Hh (IC50= 1.5 μM) without significantly affecting Wnt signaling (IC50≥ 30 μM).1HPI-1 suppresses Hh activation induced by loss o...
T11170 EIF4A3-IN-1 Others
eIF4A3-IN-1 is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor (IC50=0.26 μM; Kd=0.043 μM), which binds to a non-ATP binding site of eIF4A3 and shows significant cellular nonsense-mediated RNA decay (NMD...
T36783 BPIQ-II (hydrochloride)
BPIQ-II is a linear imidazoloquinazoline that potently inhibits the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 8 pM). It is selective for EGFR over an assortment of other tyrosine and ...
T37338 N-3-oxo-pentanoyl-L-Homoserine lactone
N-3-oxo-pentanoyl-L-Homoserine lactone is a chain-shortened derivative of the bacterial quorum sensing signaling molecule N-3-oxo-octanoyl-L-homoserine lactone .1It inhibits binding of the autoinducer N-3-oxo-hexanoyl ho...
T69555 XUN49524
XUN49524 also known as Vezf1-IN-T4, is an inhibitor of the pro-angiogenic activity of the zinc finger transcription factor Vezf1. XUN49524 was first reported in Molecules (2018), 23(7), 1615/1-1615/15 . This product has ...
T38328 CU-32
CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (cGAS; IC50= 0.45 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS ...
T61306 SRI-41315
SRI-41315, a chemical compound, effectively addresses premature termination codons (PTCs) associated with cystic fibrosis in immortalized and primary human bronchial epithelial cells. It induces a prolonged pause at stop...
T82866 Biotin-PEG-Biotin (MW 20000)
Biotin-PEG-Biotin (MW 20000) is a bifunctional PEG derivative featuring biotin labels at each terminal end. As an enzyme co-factor, biotin facilitates protein labeling, while PEG, known for its hydrophilic nature and low...
T72928 CDK4/6-IN-15
CDK4/6-IN-15, an orally active and selective inhibitor of CDK4/6, effectively halts the growth of cancer cells by arresting the cell cycle at the G1 phase and inhibiting the phosphorylation of the retinoblastoma tumor su...
T38329 CU-76
CU-76 is an inhibitor of cyclic GMP-AMP synthase (cGAS; IC50= 0.24 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sens...
T71641 BMS-593214
BMS-593214 is an active site-directed factor (F) VIIa inhibitor that exhibits antithrombotic and antihaemostatic properties. It acts as a direct competitive inhibitor of human FVIIa and a non-competitive inhibitor of Vii...
T36404 PRLX-93936
PRLX-93936 is an analog of erastin that has antitumor activity. It inhibits the hypoxia-inducible factor 1 (HIF-1) signaling pathway under hypoxic conditions (IC50 = 0.09 μM in a cell-based reporter assay). PRLX-93936 (1...
T68393 SNX-7081
NX-7081 is a novel small molecule inhibitor of Hsp90, which blocks components of inflammation, including cytokine production, protein kinase activity, and angiogenic signaling. SNX-7081 showed strong binding affinity to ...
T41155 MS 154
MS 154 is a potent and selective cereblon-recruiting Degrader (PROTAC®) of mutant epidermal growth factor receptor (EGFR), comprising a cereblon-binding moiety joined by a linker to gefitinib(Iressa). MS 154 decreases EG...
T36523 Extracellular Death Factor
Programmed cell death in bacteria is dependent on a system of cell-to-cell communication termed quorum sensing. Extracellular death factor (EDF) is a linear pentapeptide that communicating cells produce and release, whic...
T38045 Cholesterol β-D-Glucoside
Cholesterol β-D-glucoside is a derivative of cholesterol that contains β-D-glucose . It is formed from cholesterol and glucosylceramide by β-glucosidase 1. It activates heat shock transcription factor 1 (Hsf1) in respons...
T36461 CAY10748 CAY10748
CAY10748 is an agonist of stimulator of interferon genes (STING; IC50= 0.3794 μM in a competition binding assay).1It activates STING in STING-expressing, but not STING knockout, THP-1 cells (EC50s = 0.287 and >100 μM, re...
T36627 Lysine-specific Demethylase Inhibitor (1C) (hydrochloride)
Lysine-specific demethylase inhibitor (1C) (LSD inhibitor (1C)) is an inhibitor of LSD1, a repressive demethylase selective for histone H3 lysine 4 (H3K4).1,2LSD inhibitor (1C) inhibits LSD1 activity by 85.9% when used a...
T36221 2-chloro Palmitic Acid
2-chloro Palmitic acid is a monochlorinated form of palmitic acid . It is produced in a myeloperoxidase (MPO) and time-dependent manner in neutrophils stimulated by phorbol 12-myristate 13-acetate . 2-chloro Palmitic aci...
T35940 Darinaparsin Dimethylarsinic glutathione,Darinaparsin
Darinaparsin is a dimethylated arsenic linked to glutathione. It is cytotoxic to DU145, LNCaP, and PC3 prostate cancer cells (IC50s = 5-10 &#181M) and patient-derived primary prostate cancer cells (IC50s = 2.5-20 &#181M)...

Compounds

Dexamethasone acetate
T0947
Synonym: Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471
Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, Annexin A, NOS, Antibacterial, Autophagy
PCI-27483
T3469
Synonym: PCI27483
Target: Others
IOX2
T1823
Synonym: IOX 2,JICL38
Target: HIF/HIF Prolyl-Hydroxylase
Osteogenic Growth Peptide, OGP acetate
TP1820L
Synonym: Osteogenic Growth Peptide, OGP acetate(132996-61-3 free base)
Target: Others
Sulfaphenazole
T4567
Synonym: Plisulfan,Raziosulfa,Depocid,Depotsulfonamide
Target: P450, Antibacterial
H-9 dihydrochloride
T22833
Synonym:
Target: EGFR, 5-HT Receptor, PKA
Metarrestin
T12006
Synonym: ML246
Target: DNA/RNA Synthesis
Ganitumab
T76810
Synonym: AMG 479
Target: IGF-1R
Clindamycin hydrochloride monohydrate
T22297
Synonym: Clindamycin alcoholate
Target: Antibiotic
Bragsin2
T14775
Synonym: 6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one,Bragsin 2
Target: Others
4-CPPC
T38293
Synonym:
Target: Others
Darexaban
T31206
Synonym: YM 150,Darexaban, Tanexaban,YM150
Target: Factor Xa
PF-3450074
T16500
Synonym: PF-74
Target: HIV Protease
DL-Penicillamine
T0983L
Synonym: 3-Sulfanylvaline
Target: Antibiotic
CCT036477
T26968
Synonym: CCT 036477,CCT-036477
Target:
YM-75466
T29190
Synonym: YM 466,YM-466,YM75466,YM 75466,YM-75466 Free
Target:
Bz-IEGR-pNA (acetate)
T35926
Synonym:
Target:
Osteogenic Growth Peptide, OGP
TP1820
Synonym:
Target:
8(S)-HEPE
T37157
Synonym:
Target:
UR-1505
T29072
Synonym: UR1505,UR 1505
Target:
α-Helical CRF(9-41)
TP2048
Synonym: α-helical CRF 9-41
Target:
NSC-670224
T25888
Synonym: NSC 670224
Target:
CAY10669
T35818
Synonym:
Target:
S961 TFA (1083433-49-1 free base)
TP1361
Synonym: S961 TFA
Target:
CKD-712
T27033
Synonym: CKD 712,CKD712
Target:
Mequitamium iodide
T28015
Synonym: LG-30435,LG 30435,LG30435
Target:
Isovaleryl-L-carnitine (chloride)
T36098
Synonym:
Target:
Anumigilimab
T76908
Synonym:
Target:
Prohibitin ligand 1
T60722
Synonym:
Target:
Milvexian TFA
T70170
Synonym:
Target:
HPI-1 (hydrate)
T35538
Synonym: HPI-1 hydrate
Target:
eIF4A3-IN-1
T11170
Synonym:
Target: Others
BPIQ-II (hydrochloride)
T36783
Synonym:
Target:
N-3-oxo-pentanoyl-L-Homoserine lactone
T37338
Synonym:
Target:
XUN49524
T69555
Synonym:
Target:
CU-32
T38328
Synonym:
Target:
SRI-41315
T61306
Synonym:
Target:
Biotin-PEG-Biotin (MW 20000)
T82866
Synonym:
Target:
CDK4/6-IN-15
T72928
Synonym:
Target:
CU-76
T38329
Synonym:
Target:
BMS-593214
T71641
Synonym:
Target:
PRLX-93936
T36404
Synonym:
Target:
SNX-7081
T68393
Synonym:
Target:
MS 154
T41155
Synonym:
Target:
Extracellular Death Factor
T36523
Synonym:
Target:
Cholesterol β-D-Glucoside
T38045
Synonym:
Target:
CAY10748
T36461
Synonym: CAY10748
Target:
Lysine-specific Demethylase Inhibitor (1C) (hydrochloride)
T36627
Synonym:
Target:
2-chloro Palmitic Acid
T36221
Synonym:
Target:
Darinaparsin
T35940
Synonym: Dimethylarsinic glutathione,Darinaparsin
Target:
1 2
カタログ番号 製品名 別名 ターゲット
TN2322 Yangambin Calcium Channel , PAFR
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti...
TN1567 Delphinidin chloride Estrogen Receptor/ERR , VEGFR
Delphinidin chloride, a natural plant pigment found in berries and red wine, is a precursor of certain anthocyanins. Delphinidin chloride induces the release of nitric oxide from the vascular endothelium, resulting in va...
T41139 Echinocystic acid 28-O-β-D-glucoside
Echinocystic acid 28-O-β-D-glucoside is a metabolite resulting from the microbial oxidation and glucosidation of Echinocystic acid. It exhibits inhibitory activity towards the tissue factor pathway, with an IC50 value me...
TN2763 2-Hydroxy-3-methoxybenzoic acid glucose ester PAFR
2-Hydroxy-3-methoxybenzoic acid glucose ester shows a potent antagonistic activity against platelet activating factor (PAF), it can prevent the mice from the PAF-induced death at a dose of 300 micrograms/mouse.
TN4749 Pepluanin A P-gp
Pepluanin A, shows a very high activity for a jatrophane diterpene, outperforming cyclosporin A by a factor of at least 2 in the inhibition of Pgp-mediated daunomycin transport.
TN3572 Calyxin H HSP
Calyxin H at 1uM can increase the expression of heat shock factor 1 (HSF1), it has a possible application as a heat shock protein (HSP) inducer.
TN4126 Gentiside B Others
Gentiside B is a potent inducer of neurite outgrowth on PC12 cells, it shows a significant neuritogenic activity at 30 microM against PC12 cells that is comparable to that seen for the best nerve growth factor (NGF) conc...
TN5264 Xanthoxyletin TNF , NOS , ROS , COX , Antifection
Xanthoxyletin shows potent antibacterial, fungicidal, and algicidal properties, it also has anticancer, and anti-inflammatory activities. It shows an inhibitory effect on iNOS protein expression at 10 microM, it also can...
TN4664 Norarmepavine Others
N-norarmepavine shows significant cytotoxic activities against HL-60 carcinoma cell line with inhibitory ratios of 51.43% at concentration of 1 x 10(-5) M. Norarmepavine shows inhibition against Trypanosoma cruzi. D-(+)-...
TN3706 Coronarin A
Coronarin, A, B, C, and D are cytotoxic prinicples from the rhizomes of Hedychium coronarium, Zingiberaceae. Coronarin A exhibits good growth inhibition activities on HUVEC proliferation, it effectively suppresses the gr...
T37008 Reveromycin A
Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antip...
TN5474 Bonducellin
Bonducellin has anti-inflammatory activities, it can significantly and dose-dependently inhibit the inflammatory mediators; nitric oxide (NO), and cytokines [tumor necrosis factor (TNF)-alpha and interleukin (IL)-12. Bon...
TN4291 Isofuranodiene IL Receptor , NOS
Isofuranodiene protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases. Isofuranodiene has anticancer activity, by inhibiting...
T38330 Collinin
Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Col...
T35741 Gliovirin
Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the pa...
T36563 (E)-Guggulsterone
Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulat...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPH-00987 ARID1A Protein, Human, Recombinant (His & Myc) Human Baculovirus Insect Cells
ARID1A Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 32.4 kDa and the accession number is O14497.
TMPH-00988 ARID1A Protein, Human, Recombinant (E. coli, His & Myc) Human E. coli
ARID1A Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.4 kDa and the accession number is O14497.
TMPJ-01470 SCF Protein, Human, Recombinant Human E. coli
Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultu...
TMPJ-00135 BDNF Protein, Human/Murine/Rat, Recombinant Human,Mouse,Rat E. coli
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. I...
TMPJ-01469 NGF Protein, Human, Recombinant (E. colli) Mouse E. coli
NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family ...
TMPY-04483 IRAK4 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPY-02700 BCL2 Protein, Human, Recombinant (His) Human E. coli
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a...
TMPJ-01011 FGF-9 Protein, Mouse, Recombinant (His) Mouse E. coli
Fibroblast growth factor-9 (FGF-9) is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted mouse FGF-9 lacks the N-terminal 1-3 aa and shares >98% sequence identity with rat, human, equine, porcine a...
TMPK-00151 Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli sugge...
TMPH-02184 Telethonin Protein, Human, Recombinant (GST) Human E. coli
Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk. Telethonin Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST t...
TMPK-00428 HER2/ErbB2 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for t...
TMPH-02385 Lake Victoria marburgvirus (MARV) (strain Musoke-80) VP30 Protein (His & Myc) MARV E. coli
Acts as a transcription anti-termination factor immediately after transcription initiation, but does not affect transcription elongation. This function has been found to be dependent on the formation of an RNA secondary ...
TMPH-00106 TBP1 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) Arabidopsis thaliana E. coli
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a ro...
TMPK-00671 Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His) Rhesus HEK293 Cells
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli sugge...
TMPK-00755 Complement Factor D/CFD Protein, Human, Recombinant (hFc) Human HEK293 Cells
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli sugge...
TMPK-01155 MANSC1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
MANSC1 contains 1 MANSC domain. MANSC is a seven-cysteine-containing domain present in animal membrane and extracellular proteins. MANSC (motif at N terminus with seven cysteines) is a novel domain with a well-conserved ...
TMPY-03861 Amelotin Protein, Human, Recombinant (mFc) Human HEK293 Cells
Amelotin (AMTN) is a tooth enamel protein which is expressed in maturation-stage ameloblasts and also in the internal basal lamina of junctional epithelium, a unique epithelial structure attached to the tooth surface whi...
TMPY-01762 IGF2BP-2 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a member of the IGF-II mRNA-binding protein (IMP) family. IGF2BP2 is a member of a family of mRNA binding proteins that, collectively, have been shown to b...
TMPH-02233 P4HTM Protein, Human, Recombinant (His & SUMO) Human E. coli
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic...
TMPY-02581 STAT4 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
High expression of STAT4 in gastric cancer predicted a better clinical outcome. STAT4 might be a useful biomarker to identify patients at high risk of recurrence after gastrectomy. Genetic variants in the transcription f...
TMPK-00888 TGF alpha Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) and of nonsyndromic cleft palate only (NS-CPO). Biologic supp...
TMPJ-01054 PAFAHB Protein, Human, Recombinant (His) Human E. coli
Platelet-Activating Factor Acetylhydrolase IB Subunit β (PAFAHB) is a cytoplasmic hydrolase. PAFAHB is a member of the GDSL lipolytic enzyme family. It also belongs to Platelet-activating factor acetylhydrolase IB beta/g...
TMPJ-00345 IGF2BP-2 Protein, Human, Recombinant (His) Human E. coli
Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to...
TMPH-01207 DOCK8 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally a...
TMPK-00023 Midkine Protein, Human, Recombinant (His & Avi) Human E. coli
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue hom...
TMPK-00024 Midkine Protein, Human, Recombinant (His & Avi), Biotinylated Human E. coli
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue hom...
TMPK-00812 Midkine Protein, Mouse, Recombinant (His) Mouse E. coli
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue hom...
TMPH-02623 DOCK8 Protein, Mouse, Recombinant (His) Mouse P. pastoris (Yeast)
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally a...
TMPK-00757 TGF alpha Protein, Human, Recombinant (hFc) Human HEK293 Cells
Transforming growth factor-alpha (TGFA) has been proposed as a candidate gene in the etiology of nonsyndromic cleft lip with or without cleft palate (NS-CL/P) and of nonsyndromic cleft palate only (NS-CPO). Biologic supp...
TMPY-01360 FGFRL1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Fibroblast growth factor receptor-like 1 (FGFRL1) also known as Fibroblast growth factor receptor 5 (FGFR5), is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserv...
TMPK-01268 Complement C2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to health...
TMPH-02622 DOCK8 Protein, Mouse, Recombinant (E. coli, His) Mouse E. coli
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally a...
TMPJ-00507 EIF4E Protein, Human, Recombinant Human E. coli
Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and int...
TMPJ-00145 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to ...
TMPJ-00164 IGFBP-5 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Insulin-Like Growth Factor-Binding Protein 5 (IGFBP-5) is a secreted protein that belongs to the insulin-like growth factor (IGF) binding proteins superfamily. Members of this family prolong the half-life of the IGFs. Th...
TMPY-03440 Sts1 Protein, Human, Recombinant (His) Human E. coli
UBASH3B contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. UBASH3B was found to inhibit endocytosis of ep...
TMPK-00564 TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of...
TMPH-00867 ADAMTS4 Protein, Human, Recombinant (GST) Human E. coli
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neu...
TMPY-00624 PEAR1 Protein, Rat, Recombinant (His) Rat Baculovirus Insect Cells
Platelet endothelial aggregation receptor-1 (PEAR1), an epidermal growth factor repeat-containing transmembrane receptor, is known to participate in platelet contact-induced activation. Platelet endothelial aggregation r...
TMPK-00096 FGF-10 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated Human E. coli
Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling de...
TMPY-02838 FGFBP3 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
FGFBP3 is a member of the fibroblast growth factor-binding protein family. Members of this family binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. Fibroblast growth factors (FGFs) are impo...
TMPJ-00490 Serpin A5 Protein, Human, Recombinant (His) Human HEK293 Cells
Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent i...
TMPJ-00553 Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His) Human HEK293 Cells
Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive...
TMPJ-00456 APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in th...
TMPK-00864 DDT Protein, Human, Recombinant (His) Human E. coli
D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum ...
TMPK-01257 DDT Proten, Canine, Recombinant (His) Canine E. coli
D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum ...
TMPJ-01396 PIN4 Protein, Human, Recombinant (His) Human E. coli
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4(PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PA...
TMPY-03439 UBASH3A Protein, Human, Recombinant (aa 354-623, His) Human E. coli
UBASH3A is a member of the T-cell ubiquitin ligand (TULA) family. This family consists of two members. Both of them can negatively regulate T-cell signaling. UBASH3A can facilitate growth factor withdrawal-induced apopto...
TMPJ-01173 TFF3 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Trefoil factors (TFF) are secretory products of mucin producing cells. They play a key role in the maintenance of the surface integrity of oral mucosa and enhance healing of the gastrointestinal mucosa by a process calle...
TMPJ-01281 COL21A1 Protein, Human, Recombinant (His) Human HEK293 Cells
Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interrupted helices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, one TSP N-terminal (TSPN) do...
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ARID1A Protein, Human, Recombinant (His & Myc)
TMPH-00987
Species: Human
Expression System: Baculovirus Insect Cells
ARID1A Protein, Human, Recombinant (E. coli, His & Myc)
TMPH-00988
Species: Human
Expression System: E. coli
SCF Protein, Human, Recombinant
TMPJ-01470
Species: Human
Expression System: E. coli
BDNF Protein, Human/Murine/Rat, Recombinant
TMPJ-00135
Species: Human,Mouse,Rat
Expression System: E. coli
NGF Protein, Human, Recombinant (E. colli)
TMPJ-01469
Species: Mouse
Expression System: E. coli
IRAK4 Protein, Human, Recombinant (His)
TMPY-04483
Species: Human
Expression System: Baculovirus Insect Cells
BCL2 Protein, Human, Recombinant (His)
TMPY-02700
Species: Human
Expression System: E. coli
FGF-9 Protein, Mouse, Recombinant (His)
TMPJ-01011
Species: Mouse
Expression System: E. coli
Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
TMPK-00151
Species: Mouse
Expression System: HEK293 Cells
Telethonin Protein, Human, Recombinant (GST)
TMPH-02184
Species: Human
Expression System: E. coli
HER2/ErbB2 Protein, Human, Recombinant (His & Avi)
TMPK-00428
Species: Human
Expression System: HEK293 Cells
Lake Victoria marburgvirus (MARV) (strain Musoke-80) VP30 Protein (His & Myc)
TMPH-02385
Species: MARV
Expression System: E. coli
TBP1 Protein, Arabidopsis thaliana, Recombinant (His & SUMO)
TMPH-00106
Species: Arabidopsis thaliana
Expression System: E. coli
Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)
TMPK-00671
Species: Rhesus
Expression System: HEK293 Cells
Complement Factor D/CFD Protein, Human, Recombinant (hFc)
TMPK-00755
Species: Human
Expression System: HEK293 Cells
MANSC1 Protein, Mouse, Recombinant (His)
TMPK-01155
Species: Mouse
Expression System: HEK293 Cells
Amelotin Protein, Human, Recombinant (mFc)
TMPY-03861
Species: Human
Expression System: HEK293 Cells
IGF2BP-2 Protein, Human, Recombinant (His & GST)
TMPY-01762
Species: Human
Expression System: Baculovirus Insect Cells
P4HTM Protein, Human, Recombinant (His & SUMO)
TMPH-02233
Species: Human
Expression System: E. coli
STAT4 Protein, Human, Recombinant (His)
TMPY-02581
Species: Human
Expression System: Baculovirus Insect Cells
TGF alpha Protein, Mouse, Recombinant (hFc)
TMPK-00888
Species: Mouse
Expression System: HEK293 Cells
PAFAHB Protein, Human, Recombinant (His)
TMPJ-01054
Species: Human
Expression System: E. coli
IGF2BP-2 Protein, Human, Recombinant (His)
TMPJ-00345
Species: Human
Expression System: E. coli
DOCK8 Protein, Human, Recombinant (His)
TMPH-01207
Species: Human
Expression System: P. pastoris (Yeast)
Midkine Protein, Human, Recombinant (His & Avi)
TMPK-00023
Species: Human
Expression System: E. coli
Midkine Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00024
Species: Human
Expression System: E. coli
Midkine Protein, Mouse, Recombinant (His)
TMPK-00812
Species: Mouse
Expression System: E. coli
DOCK8 Protein, Mouse, Recombinant (His)
TMPH-02623
Species: Mouse
Expression System: P. pastoris (Yeast)
TGF alpha Protein, Human, Recombinant (hFc)
TMPK-00757
Species: Human
Expression System: HEK293 Cells
FGFRL1 Protein, Mouse, Recombinant (His)
TMPY-01360
Species: Mouse
Expression System: HEK293 Cells
Complement C2 Protein, Cynomolgus, Recombinant (His)
TMPK-01268
Species: Cynomolgus
Expression System: HEK293 Cells
DOCK8 Protein, Mouse, Recombinant (E. coli, His)
TMPH-02622
Species: Mouse
Expression System: E. coli
EIF4E Protein, Human, Recombinant
TMPJ-00507
Species: Human
Expression System: E. coli
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (hFc)
TMPJ-00145
Species: Mouse
Expression System: HEK293 Cells
IGFBP-5 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00164
Species: Human
Expression System: HEK293 Cells
Sts1 Protein, Human, Recombinant (His)
TMPY-03440
Species: Human
Expression System: E. coli
TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His)
TMPK-00564
Species: Cynomolgus
Expression System: HEK293 Cells
ADAMTS4 Protein, Human, Recombinant (GST)
TMPH-00867
Species: Human
Expression System: E. coli
PEAR1 Protein, Rat, Recombinant (His)
TMPY-00624
Species: Rat
Expression System: Baculovirus Insect Cells
FGF-10 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated
TMPK-00096
Species: Human
Expression System: E. coli
FGFBP3 Protein, Human, Recombinant (His)
TMPY-02838
Species: Human
Expression System: Baculovirus Insect Cells
Serpin A5 Protein, Human, Recombinant (His)
TMPJ-00490
Species: Human
Expression System: HEK293 Cells
Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His)
TMPJ-00553
Species: Human
Expression System: HEK293 Cells
APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc)
TMPJ-00456
Species: Mouse
Expression System: HEK293 Cells
DDT Protein, Human, Recombinant (His)
TMPK-00864
Species: Human
Expression System: E. coli
DDT Proten, Canine, Recombinant (His)
TMPK-01257
Species: Canine
Expression System: E. coli
PIN4 Protein, Human, Recombinant (His)
TMPJ-01396
Species: Human
Expression System: E. coli
UBASH3A Protein, Human, Recombinant (aa 354-623, His)
TMPY-03439
Species: Human
Expression System: E. coli
TFF3 Protein, Mouse, Recombinant (His)
TMPJ-01173
Species: Mouse
Expression System: HEK293 Cells
COL21A1 Protein, Human, Recombinant (His)
TMPJ-01281
Species: Human
Expression System: HEK293 Cells
カタログ番号 製品名
L1380 Transcription Factor-Targeted Compound Library

695 compounds
Well-chosen 695 compounds with unique structures targeting transcription factor;
L7110 Anti-Hypertension Compound Library

678 compounds
678 hypertension-related small molecules for high-throughput and high-content screening.