| TN1040 |
Skullcapflavone II
|
|
COX
,
Antibacterial
,
TGF-beta/Smad
|
|
Skullcapflavone II is a flavonoid derived from Scutellaria baicalensis, a widely used herbal medicine in anti-inflammatory and anticancer therapy. Skullcapflavone II may have therapeutic potential for the treatment of al... |
| T7994 |
3-Methoxyflavone
|
|
Antiviral
|
|
3-Methoxyflavone is a Flavonoids, with antiviral activity |
| TN2151 |
Rhamnocitrin
|
|
Others
|
|
Rhamnocitrin can enhance the immune function, improve the formation of spleen cells of mice serum hemolysin of chicken red blood cell immune. |
| TN1740 |
Homoeriodictyol
|
|
5-HT Receptor
,
transporter
,
Sodium Channel
,
Drug Metabolite
|
|
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotoni... |
| TN1621 |
Eriodictyol-7-O-glucoside
|
|
Nrf2
|
|
Eriodictyol-7-O-glucoside is an Nrf2 activator conferring protection against Cisplatin-induced toxicity. Eriodictyol-7-O-glucoside is a flavonoid and a free radical scavenger with antioxidant activity in pistachio skin. |
| T6S0139 |
Neobavaisoflavone
|
|
Apoptosis
,
DNA/RNA Synthesis
|
|
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si... |
| T3882 |
4”-O-Glucosylvitexin
|
glucosylvitexin |
Thrombopoietin Receptor
|
|
4”-O-Glucosylvitexin (glucosylvitexin) inhibits TPO activity. |
| TN3209 |
3′,4′,7-Trihydroxyflavone
|
|
ATPase
,
Others
,
p38 MAPK
,
NF-κB
|
|
3'4'7-Trihydroxyflavone can markedly inhibit the receptor activator of nuclear factor kappa B ligand (RANKL) induced osteoclastic differentiation from mouse bone marrow derived macrophages (BMMs), it inhibits osteoclasto... |
| T5722 |
Nevadensin
|
Pedunculin |
Anti-infection
,
Antibacterial
|
|
Nevadensin is an important herb-based constituent inhibiting estragole bioactivation. Nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat. It also exhibits inhibition acti... |
| T0795 |
Rutin
|
Quercetin 3-O-rutinoside,Rutoside |
Beta Amyloid
,
Prostaglandin Receptor
,
Autophagy
|
|
Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties. |
| T5773 |
Moslosooflavone
|
5-hydroxy-7,8-dimethoxyflavone |
NF-κB
,
Reactive Oxygen Species
|
|
Moslosooflavone (5-hydroxy-7,8-dimethoxyflavone) has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice. 5-hydroxy-7,8-dimethoxyflavone significantly inhibits the transcriptional activi... |
| T4S0094 |
Hydroxygenkwanin
|
Luteolin 7-methylether,7-O-Methylluteolin |
Antioxidant
|
|
1. Hydroxygenkwanin (Luteolin 7-methylether) possesses significant the antioxidative activity . 2. Hydroxygenkwanin has cytotoxicity, may be an effective natural product to treat glioma, and the combination of Apigenin a... |
| TN2158 |
Robinetin
|
3,3',4',5',7-Pentahydroxyflavone |
Anti-infection
,
HIV Protease
,
Antibacterial
|
|
Robinetin (3,3',4',5',7-Pentahydroxyflavone) has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency. |
| TN1259 |
Complanatoside B
|
|
Others
|
|
Complanatoside B is a flavonoid natural product with anti-inflammatory properties. |
| T22417 |
Rutin hydrate
|
Rutoside,Sophorin,Quercetin-3-O-rutinoside |
Beta Amyloid
,
Others
,
Autophagy
|
|
Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit. |
| T1686 |
Hematoxylin
|
Hydroxybrazilin,Natural Black 1,Haematoxylin |
Beta Amyloid
,
Others
|
|
Hematoxylin (Natural Black 1) is a dye obtained from the heartwood of logwood (Haematoxylon campechianum Linn., Leguminosae) used as a stain in microscopy and in the manufacture of ink. |
| TN2130 |
Manghaslin
|
Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside |
AChE
,
Glucosidase
|
|
Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) has considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenolic-rich litchi pulp extracts. Manghaslin also shows inhibito... |
| T7437 |
3-(3-Hydroxyphenyl)propionic Acid
|
m-Hydroxyphenylpropionic acid,3-Hydroxyhydrocinnamic acid |
Others
,
Endogenous Metabolite
|
|
3-(3-Hydroxyphenyl)propionic Acid (m-Hydroxyphenylpropionic acid) is one of the major metabolites of ingested caffeic acid.it inhibited osteoclastogenesis and bone osteoclastic resorptive activity. |
| T2S2150 |
Noricaritin
|
|
Others
|
|
Noricaritin is a flavonoid derived from Epimedium root. |
| TN5028 |
Sinensin
|
ZINC38908691 |
Others
|
|
Sinensin is a flavonoid from the herbs of Cudrania cochinchinensis. |
| TN1489 |
3'-Methoxyapiin
|
Graveobioside B,3'-Methoxy apiin,Chrysoeriol 7-apiosylglucoside |
Others
|
|
3'-Methoxyapiin (Graveobioside B) is a flavonoid from the herbs of Eminium spiculatum. |
| T13761 |
Luteolin 7-diglucuronide
|
|
Others
|
|
Luteolin 7-diglucuronide is the major flavonoid isolated from Verbena officinalis and Aloysia triphylla. |
| TN7128 |
4,6,3',4'-Tetrahydroxyaurone
|
aureusidin |
Others
|
|
4,6,3',4'-Tetrahydroxyaurone is a flavonoid from the herbs of Heleocharis dulcis. |
| TN3689 |
Comanthoside A
|
Comanthosid A |
Others
|
|
Comanthoside A (Comanthosid A) is a naturally occurring flavonoid glycoside isolated from Comanthosphace japonica.Comanthoside A is also a key intermediate in the synthesis of Linaroside and Comanthoside B. Comanthoside ... |
| T0228 |
Methyl-Hesperidin
|
|
Akt
,
PKC
|
|
Methyl Hesperidin, a flavanone glycoside (flavonoid) (C28H34O15), is abundant in citrus fruits. Its aglycone form is called hesperetin. |
| TN1808 |
Isovitexin 2''-O-arabinoside
|
|
Others
|
|
Isovitexin 2''-O-arabinoside is a flavonoid found in the alfalfa plant. |
| T2O2770 |
Agarotetrol
|
|
Others
|
|
Agarotetrol is a flavonoid derivative isolated from agarwood. |
| T8263 |
3,4'-Dihydroxyflavone
|
|
Influenza Virus
|
|
3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid. 3,4'-Dihydroxyflavone (3,4'-DHF) shows antiviral activity against Influenza A virus. |
| T13514 |
5-MethoxyPinocembroside
|
|
Others
|
|
5-MethoxyPinocembroside is a flavonoid isolated from leaves of Moringa oleifera. |
| TN1082 |
Apigenin 7-O-malonylglucoside
|
Apigenin 7-O-(6''-O-malonylglucoside) |
|
|
Apigenin 7-O-malonylglucoside (Apigenin 7-O-(6''-O-malonylglucoside)) is found in chrysanthemums and is a flavonoid as well as a glycoside. |
| T8158 |
Tilianin
|
|
Others
|
|
Tilianin is a flavonoid glycoside of Dragocephalum moldavicum L. |
| T4130 |
Complanatuside
|
Complanatoside |
Others
|
|
Complanatuside (Complanatoside) is a flavonoid isolated from the traditional Chinese medicine Semen Astragali Complanati. |
| TN3120 |
5-Hydroxy-7-acetoxy-8-methoxyflavone
|
|
Histone Demethylase
,
Antiviral
|
|
5-Hydroxy-7-acetoxy-8-methoxyflavone is a flavonoid compound that inhibits lipid peroxidation and may have anti-influenza virus activity. |
| T6S1768 |
Narcissin
|
Isorhamnetin 3-Rutinoside,Narcissoside |
Antioxidant
|
|
Narcissin (Isorhamnetin 3-Rutinoside), with synergism of B.flavum flavonoid and rutin, could be responsible for stronger protection against mitochondrial induced oxidative stress. |
| T2794 |
Astilbin
|
Neoastilbin,Taxifolin 3-O-rhamnoside,Isoastilbin,Taxifolin 3-rhamnoside,Neoisoastilbin |
TNF
,
NF-κB
,
Nrf2
|
|
Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations. |
| T5S2139 |
Epimedin A1
|
Hexandraside F |
Others
|
|
Epimedin A1 (Hexandraside F)(Hexandraside F) is a flavonoid extracted from Herba Epimedii which is one of commonly used Chinese medicines. |
| T2933 |
Wogonin
|
Vogonin |
Apoptosis
,
Wnt/beta-catenin
,
CDK
,
Autophagy
|
|
Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties. |
| T2O2744 |
Alpha-Naphthoflavone
|
7,8-benzoflavone |
Aromatase
|
|
alpha-Naphthoflavone (7,8-benzoflavone), a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM. |
| T10183 |
6-Methoxytricin
|
|
Others
|
|
6-Methoxytricin is a flavonoid isolated from Artemisia iwayomogi. It is an inhibitor on aldose reductase (AR) and advanced glycation endproduct (AGE) formation activities (IC50s: 30.29 μM and 134.88 μM). 6-Methoxytricin ... |
| TN7233 |
Pseudobaptigenin
|
Psi-baptigenin |
Others
|
|
Pseudobaptigenin (Psi-baptigenin) is an isoflavone, a flavonoid lipid molecule that is a natural product found in Pterocarpus marsupium, Dalbergia spruceana. |
| TN7067 |
3',5-Di-O-methyl quercetin
|
3,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-5-methoxy-4H-chromen-4-one |
Others
|
|
3',5-Di-O-methyl quercetin (3,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-5-methoxy-4H-chromen-4-one) is a flavonoid natural product. |
| T3325 |
Liquiritigenin
|
4',7-Dihydroxyflavanone |
Estrogen Receptor/ERR
,
Estrogen/progestogen Receptor
|
|
Liquiritigenin (4',7-Dihydroxyflavanone), a flavonoid aglycone from licorice, is a highly selective estrogen receptor β (ERβ) agonist. |
| T2844 |
Hyperoside
|
Quercetin 3-galactoside,Hyperin |
Others
,
Influenza Virus
,
Antifungal
|
|
Hyperoside (Hyperin) is a naturally occuring flavonoid compound which shows multiple bioactivities, including myocardial protection, anti-redox, and anti-inflammatory activities. |
| T4S0217 |
HOMOPLANTAGININ
|
|
TNF
,
NF-κB
|
|
Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and shows potent inhibitory activities against influenza. |
| T5S1526 |
Apigenin-7-O-(2G-rhamnosyl)gentiobioside
|
Apigenin 7-O-(2G-rhamnosyl)gentiobioside,Apigenin 7-(2-Rhamnosylgentiobioside) |
Others
|
|
Apigenin-7-O-(2G-rhamnosyl)gentiobioside is a flavonoid glycoside compound extracted from Lonicera gracilipes var. glandulosa. |
| T2757 |
Myricitrin
|
Myricetrin,Myricitrine |
PKC
|
|
Myricitrin (Myricitrine), a flavonoid compound isolated from the root bark of Myrica cerifera, exerts antinociceptive effects. |
| TN1819 |
Kaempferol 3-neohesperidoside
|
Kaempferol 3-O-neohesperidoside |
GSK-3
,
MEK
,
PI3K
|
|
Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside), a flavonoid compound, demonstrates an insulinomimetic effect on the rat soleus muscle. |
| T2776 |
Tribuloside
|
Tiliroside |
Others
,
Antibacterial
|
|
A new cinnamolyglycoflavonoid 3-cinnamoyltribuloside (1), its precursor Tribuloside (Tiliroside) A and two known flavonoid glycosides afzelin and astilbin were isolated from Heritiera littoralis Dryand (Sterculiaceae) et... |
| TN2967 |
Pinobanksin 3-acetate
|
3-O-Acetylpinobanksin |
Others
,
Antioxidant
|
|
Pinobanksin 3-acetate (3-O-Acetylpinobanksin), a flavonoid derivative, is a strong antioxidant found in sunflowers and honey that inhibits LDL peroxidation. |
| T0725 |
Isoliquiritigenin
|
ISL,Isoliquiritigen,GU17 |
Apoptosis
,
Influenza Virus
,
Reductase
,
Autophagy
|
|
Isoliquiritigenin (ISL), an anti-tumor flavonoid from the root of Glycyrrhiza glabra, suppresses aldose reductase (IC50=320 nM). |
