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カタログ番号	製品名	別名	ターゲット
T40247	Ethofumesate		Others
	Ethofumesate is a chiral herbicide. Ethofumesate acts by inhibiting mitosis and reducing photosynthesis and plant respiration.		Others
T8561	Apcin		APC
	Apcin is a potent and competitive inhibitor of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substr...		APC
T7200	TAK-960		PLK
	TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.		PLK
TQ0317	R1530	R-1530,R 1530	VEGFR , FGFR , FLT , PDGFR
	R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.		VEGFR , FGFR , FLT , PDGFR
T19664	ON1231320	GBO-006	Apoptosis , PLK
	ON1231320 (GBO-006) is a Polo-like kinase 2 (PLK2) inhibitor.		Apoptosis , PLK
T21654	1-Oleoyl lysophosphatidic acid sodium	1-Oleoyl lysophosphatidic acid sodium salt	LPA Receptor
	1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2		LPA Receptor
T1992	Mertansine	DM1,Maytansinoid DM1	Microtubule Associated
	Mertansine (DM1) refers to the thiol-containing maytansinoid, DM1 (N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4...		Microtubule Associated
T3643	HMN-176		PLK
	HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).		PLK
T22305	Dexrazoxane	ICRF-187	Others
	Dexrazoxane (ICRF-187) is an anticancer drug used to block mitosis and arrest dividing cells. It is an iron chelator and provides cardioprotection against anthracycline toxicity.		Others
T9014	SKI-178		Apoptosis , S1P Receptor
	SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during ...		Apoptosis , S1P Receptor
T4057	Hoechst 33258 trihydrochloride	Hoechst 33258,Pibenzimol,Bisbenzimide,H 33258 trihydrochloride,bisBenzimide H 33258 trihydrochloride,HOE 33258	Parasite
	Hoechst 33258 trihydrochloride (Bisbenzimide) is a benzimidazole anti-filarial agent. it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication. it also interfe...		Parasite
T3352	XL413		cholecystokinin , Casein Kinase , Pim , CDK
	XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. XL-413 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA ...		cholecystokinin , Casein Kinase , Pim , CDK
T3567	SU 4942		Others
	SU-4942 is a modulator of tyrosine kinase signaling. SU-4942 has inhibitory effects on endothelial cell mitosis induced by VEGF and endothelial cell growth factor (ECGF).		Others
T29059	UMK57	UMK 57,UMK-57	Kinesin
	UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds, and can improve chromosome separation conservation by disrupt...		Kinesin
T16987	TAO Kinase inhibitor 1		Others , MAPK
	TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death. TAO Kinase inhibitor 1 is a selective and ATP-competitive thousand-and-one amino acid kinases inhibitor (IC50s: 11 to 15 nM for TAOK1 and 2, respectiv...		Others , MAPK
T24398	Lenaldekar	LDK	Akt , IGF-1R , S6 Kinase
	Lenaldekar (LDK) inhibits T-cell expansion and autoimmune encephalomyelitis. Lenaldekar causes dephosphorylation of members of the PI3 kinase/AKT/mTOR pathway and delays sensitive cells in late mitosis.		Akt , IGF-1R , S6 Kinase
T5699	SSE15206		Apoptosis , Microtubule Associated
	SSE15206 is a microtubule polymerization inhibitor that overcomes multidrug resistance. Causes aberrant mitosis resulting in G2/M arrest due to incomplete spindle formation in cancer cells.		Apoptosis , Microtubule Associated
T26585	AK301	AK-301,AK 301	Apoptosis , Microtubule Associated
	AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM). Colon cancer cells arrested in mitosis with AK301 readily underwent a ...		Apoptosis , Microtubule Associated
T70407	Cemadotin free base	LU103793 free base	Microtubule Associated
	Cemadotin free base(LU103793 free base) is a novel anti-limiting peptide , an analog of Dolastatin 15, a naturally occurring cytotoxic peptide that blocks mitosis and inhibits microtubules (tubulin) with a Ki of 1 μM. Ce...		Microtubule Associated
T35570	Chiauranib	CS2164	c-Fms , VEGFR , FLT , PDGFR , c-Kit , Aurora Kinase
	Chiauranib is a multi-target inhibitor against tumor angiogenesis and exhibits potent anticancer effects. Chiauranib potently inhibits the angiogenesis-related kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα and c-Kit), mitosis-...		c-Fms , VEGFR , FLT , PDGFR , c-Kit , Aurora Kinase
T9864	Debio-0123	WEE1-IN-5	Wee1
	Debio-0123 (WEE1-IN-5) is a potent, orally available and highly specific WEE1 inhibitor with an IC 50 in the low nanomolar range. Debio-0123 inhibits phospho-CDC2 which translated into an increase in DNA damage and prema...		Wee1
T9682	AZD-4877	AZD4877	Apoptosis , Kinesin
	AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and med...		Apoptosis , Kinesin
T7055	Bz-RS-ISer(3-Ph)-Ome	Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate	Others , HIV Protease
	Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle at low cytotoxicity, blocks mitosis in Vero cells, affects the size o...		Others , HIV Protease
T27407	GDC0575 monohydrochloride	ARRY-575,GDC-0575,GDC 0575,ARRY575,GDC0575	Chk
	GDC0575 monohydrochloride (ARRY575) is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2 nM. GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells by...		Chk
T29205	Zarilamide	Zarilamid
	Zarilamide is inhibitor of the nuclear division in germinating zoospore cysts of Phytophthora capsici. Zarilamide destructs the microtubule cytoskeleton, resulting in a consequent inhibition of mitosis.
T11859L	Litronesib	KF-89617,LY-2523355	Kinesin
			Kinesin
T68611	GW837016X
	GW837016X, also known as NEU-391, is a potent inhibitor of protozoan parasite proliferation. GW837016X extended life of treated mice by 50%, compared to untreated controls. At the cellular level, GW837016X inhibited mito...
T38644	Docetaxal	PNU-101383,10-Acetyl docetaxel
	Docetaxal, also known as 10-Acetyl docetaxel, is an analog of Docetaxel exhibiting potent anticancer properties. It acts as a microtubule disassembly inhibitor, effectively inhibiting mitosis.
T17163	Trifluralin		Others
	Trifluralin is a commonly used pre-emergence herbicide. It inhibits root development by interrupting mitosis and thus can control weeds as they germinate.		Others
T24699	R1498	R-1498,R 1498
	R1498 is an inhibitor of cyclin-dependent kinase 2. It also acts by targeting angiogenesis and mitosis pathways. It is well-tolerated and orally active for hepatocellular carcinoma and gastric cancer treatment.
T18361	MMAE-SMCC		Others
	MMAE-SMCC is a drug-linker conjugate designed for antibody-drug conjugates (ADC). It consists of MMAE, a potent inhibitor of mitosis and tubulin, and SMCC, a linker that facilitates the development of ADCs.		Others
T82221	Head activator neuropeptide
	Head activator neuropeptide, a mitogen for neuronal or neuroendocrine mammalian cell lines, induces mitosis by signaling through GPR37 binding [1].
T36358	Diminutol
	Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization ...
T63375	FT709
	FT709 is a selective and potent inhibitor of USP9X (IC50: 82 nM). Among others, USP9X is associated with centrosome function, EGF receptor degradation, chromosome alignment during mitosis, chemosensitization and circadia...
T76458	P34cdc2 Kinase Fragment
	P34cdc2 Kinase Fragment plays a crucial role in yeast mitosis by ensuring the completion of DNA replication and regulates microtubule polymerization in Xenopus oocytes meiosis by phosphorylating mitogen-activated protein...
T36979	Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)	Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)
	Histone H3 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.3 sequence and is biotinylated via a C-terminal GK linker. Unlike histone H3.1 and H3...
T28179	NMK-TD-100	NMK-TD 100,NMK-TD100
	NMK-TD-100 is a microtubule modulating agent with anti-proliferative activity by disrupting microtubule functions through tubulin binding. NMK-TD-100 blocks mitosis and induces apoptosis in HeLa cells by binding to tubul...
T81696	NBI-961
	NBI-961, a potent NEK2 inhibitor, suppresses proteasomal degradation and effectively induces G2/mitosis arrest and apoptosis within diffuse large B cell lymphoma (DLBCL) cells [1].
T69003	E7974
	E7974 is an analog of the sponge-derived anti-microtubule tripeptide hemiasterlin with antimitotic and potential antineoplastic activities. Hemiasterlin analog E7974 binds to the Vinca domain on tubulin, resulting in inh...
T68232	Epofolate
	Epofolate is folate receptor-targeting antimitotic agent with potential antineoplastic activity. Folate receptor-targeted epothilone BMS753493 contains an epothilone moiety linked to a single folate molecule. Mediated th...
T73195	EAPB 02303
	EAPB 02303 is a microtubule-disrupting agent and inhibitor that induces mitosis arrest and spindle assembly impairment, leading to apoptosis (programed cell death) and demonstrating antitumor activity. Furthermore, it ex...
T68363	OUN10989
	OUN10989, an analogue compound of LP-261, is a Potent Antimitotic Agent. OUN10989 exhibited potent inhibition of mitosis at the G2/M stage. OUN10989 was first reported in J. Med. Chem 54(1), 179-200; 2011 (compound 7). T...
T71207	(R)-(+)-Blebbistatin O-Benzoate
	(R)-(+)-Blebbistatin O-Benzoate is a derivative of Blebbistatin. (R)-(+)-Blebbistatin is a 1-phenyl-2-pyrrolidinone derivative and a selective inhibitor of non-muscle myosin II. It blocks cell blebbing rapidly and revers...
TP2292	Survivin (baculoviral IAP repeat-containing protein 5) (21-28)		Others
	Survivin (baculoviral inhibitor of apoptosis IAP repeat-containing protein-5) is a member of the IAP gene family, which has been implicated in both inhibitions of apoptosis and mitosis regulation1. Survivin is one of the...		Others
T62417	MELK-8a
	MELK-8a (NVS-MELK8a) is a potent and selective inhibitor of maternal embryonic leucine elongation kinase (MELK) (IC50: 2 nM). 0.42 μM). Among them, MELK plays an important role in regulating mitosis in cancer cells.
T78138	SIC5-6		Others
	SIC5-6 is a potent inhibitor of Separase, a substantial cysteine protease implicated in critical cellular processes such as chromosome segregation during mitosis and meiosis, DNA damage repair, centrosome disengagement a...		Others
T71218	AEZS-112
	AEZS-112, also known as ZEN012, is an orally active small mol. anti-cancer drug which inhibits the polymn. of tubulin at low micromolar concns. AEZS 112 dose-dependently increased non-vital hypodiploid cells and the cyto...
T70235	Cemadotin hydrochloride
	Cemadotin hydrochloride is the salt from of Cemadotin (free base), also known as, LU103793, a mitosis inhibitor potentially for the treatment of solid tumours. Cemadotin is also a synthetic derivative of Dolastatin 15,...
T61746	Anticancer agent 82
	Anticancer agent 82 is a FiVe1 derivative, an orally active and selective anticancer agent. FiVe1 binds type III intermediate filament protein vimentin ( VIM ), to induce hyperphosphorylation of Ser56, resulting selectiv...
T68743	AZD4877 HCl
	AZD4877 is a synthetic kinesin spindle protein (KSP) inhibitor with potential antineoplastic activity. KSP inhibitor AZD4877 selectively inhibits microtubule motor protein KSP (also called kinesin-5 or Eg5), which may re...

Compounds

Synonym: R-1530,R 1530

Target: VEGFR, FGFR, FLT, PDGFR

ON1231320

T19664

Synonym: GBO-006

Target: Apoptosis, PLK

1-Oleoyl lysophosphatidic acid sodium

T21654

Synonym: 1-Oleoyl lysophosphatidic acid sodium salt

Target: LPA Receptor

Mertansine

T1992

Synonym: DM1,Maytansinoid DM1

Target: Microtubule Associated

Target: Apoptosis, S1P Receptor

Hoechst 33258 trihydrochloride

T4057

Synonym: Hoechst 33258,Pibenzimol,Bisbenzimide,H 33258 trihydrochloride,bisBenzimide H 33258 trihydrochloride,HOE 33258

Target: cholecystokinin, Casein Kinase, Pim, CDK

Synonym: UMK 57,UMK-57

Target: Kinesin

TAO Kinase inhibitor 1

Target: Akt, IGF-1R, S6 Kinase

SSE15206

T5699

Synonym:

Target: Apoptosis, Microtubule Associated

AK301

T26585

Synonym: AK-301,AK 301

Target: Apoptosis, Microtubule Associated

cemadotin free base

T70407

Synonym: LU103793 free base

Target: Microtubule Associated

Chiauranib

T35570

Synonym: CS2164

Target: c-Fms, VEGFR, FLT, PDGFR, c-Kit, Aurora Kinase

Target: Apoptosis, Kinesin

Bz-RS-ISer(3-Ph)-Ome

T7055

Synonym: Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate

Target: Others, HIV Protease

GDC0575 monohydrochloride

T27407

Synonym: ARRY-575,GDC-0575,GDC 0575,ARRY575,GDC0575

Synonym: KF-89617,LY-2523355

Synonym: PNU-101383,10-Acetyl docetaxel

Synonym: R-1498,R 1498

Head activator neuropeptide

P34cdc2 Kinase Fragment

T76458

Synonym:

Target:

Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)

T36979

Synonym: Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)

Target:

NMK-TD-100

T28179

Synonym: NMK-TD 100,NMK-TD100

(R)-(+)-Blebbistatin O-Benzoate

T71207

Synonym:

Target:

survivin (baculoviral IAP repeat-containing protein 5) (21-28)

Cemadotin hydrochloride

カタログ番号	製品名	別名	ターゲット
T6213	Vinorelbine ditartrate	Vinorelbine Tartrate,Nor-5'-anhydrovinblastine ditartrate,KW-2307,Navelbine tartrate	Microtubule Associated , Autophagy
	Vinorelbine ditartrate (KW-2307), a semi-synthetic vinca alkaloid, interacts with tubulin resulting in mitosis inhibition.		Microtubule Associated , Autophagy
T0186	Docetaxel trihydrate	RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate	Apoptosis , BCL , Microtubule Associated
			Apoptosis , BCL , Microtubule Associated
T3S0209	Vincristine		ERK , p38 MAPK , NF-κB , Akt , JNK , mTOR
	Vincristine-induced nociceptive painful sensation, may be due to its potential of antioxidative, neuroprotective and calcium channel inhibitory action.Vincristine can treat MM, ERK1/2, Akt, and NF-ÎºB inhibitors are pote...		ERK , p38 MAPK , NF-κB , Akt , JNK , mTOR
TN3724	Cryptomoscatone D2		p53
	Cryptomoscatone D2 is a highly efficacious inhibitor of the G(2) checkpoint, and G(2) checkpoint inhibitors can force cells arrested in G(2) phase by DNA damage to enter mitosis.		p53
TN3721	Cryptofolione		Antifection
	Z-Cryptofolione and Cryptomoscatone D2 as highly efficacious inhibitors of the G(2) checkpoint, G(2) checkpoint inhibitors can force cells arrested in G(2) phase by DNA damage to enter mitosis. Cryptofolione shows modera...		Antifection
TN4944	Santamarine		Caspase
	Santamarine has significant anticancer activity, can inhibit L1210 cells because of its cytotoxic,cytostatic and blocking mitosis and reducing uptake of thymidine. Santamarine and reynosin show bactericidal activity agai...		Caspase
T82787	Calythropsin
	Calythropsin is a cytotoxic chalcone that exhibits a weak influence on mitosis and is presumed to similarly affect tubulin polymerization [1].
T75521	PM050489
	PM050489, a potent polyketone inhibitor of Microtubule/Tubulin isolated from the Madagascan sponge Lithoplocamia lithistoides, effectively inhibits mitosis with an IC 50 value of 26.4 nM. This compound exhibits antitumor...

天然物製品

Vinorelbine ditartrate

T6213

Synonym: Vinorelbine Tartrate,Nor-5'-anhydrovinblastine ditartrate,KW-2307,Navelbine tartrate

Target: Microtubule Associated, Autophagy

Docetaxel trihydrate

T0186

Synonym: RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate

Target: Apoptosis, BCL, Microtubule Associated

Vincristine

T3S0209

Synonym:

Target: ERK, p38 MAPK, NF-κB, Akt, JNK, mTOR

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04420	TLK1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Tousled-like kinase 1 (or protein kinase ubiquitous, PKU-beta/TLK1) is a serine/threonine protein kinase that is implicated in chromatin remodeling, DNA replication and mitosis. TLK1 has a function important for proper c...
TMPJ-01013	VCP Protein, Human, Recombinant (His)	Human	E. coli
	Valosin-Containing Protein (VCP) is a nuclear protein that belongs to the AAA ATPase family. VCP is a putative ATP-binding protein involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxi...
TMPY-04558	NEK7 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	NIMA (never in mitosis gene a)-related kinase 7, NEK7 belongs to the NIMA subfamily, NEK Ser/Thr protein kinase family, protein kinase superfamily. NEKs (NIMA-related kinases) are mammalian serine/threonine (Ser/Thr) pro...
TMPH-00769	2S albumin Protein, Glycine max, Recombinant (His & SUMO)	Glycine max	E. coli
	This is a 2S seed storage protein.; binds to mammalian chromatin, preventing the normal formation of the kinetochore complex in the centromere and leading to the disruption of mitosis. 2S albumin Protein, Glycine max, Re...
TMPH-00770	2S albumin Protein, Glycine max, Recombinant (His)	Glycine max	P. pastoris (Yeast)
	This is a 2S seed storage protein.; binds to mammalian chromatin, preventing the normal formation of the kinetochore complex in the centromere and leading to the disruption of mitosis.
TMPY-04443	NEK3 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus Insect Cells
	NEK3 (NIMA (never in mitosis gene a)-related expressed kinase 3), contains 1 protein kinase domain and is a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. Members of the NEK family of...
TMPY-03672	Survivin Protein, Human, Recombinant	Human	E. coli
	BIRC5, also known as Survivin and EPR-1, is a member of theIAP family. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but BIRC5 has only a single BIR domain. It is expressed cell cycle-...
TMPJ-00580	ZWINT Protein, Human, Recombinant (His)	Human	E. coli
	ZW10 Interactor is localized to the kinetochores from late Prophase to Anaphase and has a uniform distribution in the cytoplasm of Interphase cells. ZWINT interacts ZW10, MIS12 and NDC80 subunit of the NDC80 complex spec...
TMPY-03596	JTB Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Jumping translocation breakpoint, also known as JTB, is a member of the JTB family. Jumping translocation (JT) is an unbalanced translocation that comprises amplified chromosomal segments jumping to various telomeres. JT...
TMPH-01350	FOxM1 Protein, Human, Recombinant (GST)	Human	E. coli
	Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in t...
TMPH-01351	FOxM1 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in t...
TMPY-03442	MOB4A/MOB1B Protein, Human, Recombinant (GST)	Human	E. coli
	MST1 and MST2 are the mammalian Ste2-related protein kinases most closely related to Drosophila Hippo, a major regulator of cell proliferation and survival during development. Overexpression of MST1 or MST2 in mammalian ...
TMPH-02304	Vasohibin-2/VASH2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mito...
TMPH-01642	MELK Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity; phosphorylates BCL2L14, CDC25...
TMPH-01752	Nestin/NES Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cell...
TMPJ-01138	UBE2S Protein, Human, Recombinant (GST)	Human	E. coli
	Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activat...
TMPY-04458	TRIB2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Tribbles homolog 2, also known as TRB-2, and Trib2, is a member of the protein kinase superfamily and Tribbles subfamily (Trib1, Trib2, Trib3). The identification of tribbles as regulators of signal processing systems an...
TMPJ-00053	PRL-2 Protein, Human, Recombinant (His)	Human	E. coli
	PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational ...
TMPH-02205	Titin Protein, Human, Recombinant (His)	Human	E. coli
	Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the...
TMPH-01692	MAPK3 Protein, Human, Recombinant (His)	Human	E. coli
	Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate...
TMPH-02884	CTDP1 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit...
TMPH-02870	PDXP Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Functions as a pyridoxal phosphate (PLP) phosphatase, which also catalyzes the dephosphorylation of pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), with order of substrate preference PLP > PNP > PMP an...
TMPJ-00769	TK1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Thymidine kinase 1(TK1) belongs to the thymidine kinase family. It is located in the cytoplasm, and phosphorylated on Ser-13 in mitosis during post-translational modification. Two forms of this protein have been identifi...
TMPY-03607	Cofilin Protein, Human, Recombinant (His)	Human	E. coli
	CFL1, also known as n-cofilin, is a member of the ADF/Cofilin family. This family comprises three genes: CFL1, CFL2 and DSTN (destrin). ADF/Cofilin family members bind G-actin monomers and depolymerize actin filaments t...
TMPY-04268	NUDC Protein, Human, Recombinant (His)	Human	HEK293 Cells
	NUDC (Nuclear Distribution C, Dynein Complex Regulator) is a Protein Coding gene. NUDC consists of at least 9 exons ranging from 66 bp to 266 bp in size and 8 introns from 92 bp to 2.0 kb in length, and the total genomic...
TMPY-04375	Casein Kinase 1 alpha Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Casein kinase I isoform alpha, also known as CKI-alpha, CK1 and CSNK1A1, is a cytoplasm protein which belongs to theprotein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Casein k...
TMPY-03105	Ki67/MKI67 Protein, Human, Recombinant (GST)	Human	E. coli
	MKI67 contains 1 FHA domain and plays a key role in cell proliferation. During interphase, the MKI67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the...
TMPY-02714	PRC1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	PRC1 (protein regulator of cytokinesis 1) is a key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. It is essential for controlling the spatiotemporal formation of the...
TMPH-02846	BICD2 Protein, Mouse, Recombinant (GST)	Mouse	E. coli
	Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction...
TMPY-04385	ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Death-associated protein kinase 3, also known as DAP kinase 3, ZIP-kinase, DAPK3 and ZIPK, is a nucleus and cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP ...
TMPJ-00486	SUMO2 Protein, Human, Recombinant (His)	Human	E. coli
	Small Ubiquitin-Related Modifier 2 (SUMO2) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target p...
TMPY-04547	PBK/TOPK Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	PDZ binding kinase (PBK), also known as TOPK (T-LAK cell-originated protein kinase), is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family, and has all the chara...
TMPY-02399	TRF1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Telomeric repeat binding factor 1 (TRF1), also known as TERF1, the shelterin complex, which modulates the telomere structures. TRF1 protein structure contains a C-terminal Myb motif, a dimerization domain near its N-term...
TMPY-04567	SRPK1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Serine / threonine-protein kinase SRPK1, also known as SFRS protein kinase 1, Serine/arginine-rich protein-specific kinase 1, SR-protein-specific kinase 1 and SRPK1, is a cytoplasm and nucleus protein that belongs to the...
TMPY-01890	CLIC4 Protein, Human, Recombinant (His)	Human	E. coli
	Chloride intracellular channel protein 4, also known as Intracellular chloride ion channel protein p64H1 and CLIC4, is a member of the chloride channel CLIC family. It contains oneGST C-terminal domain. CLIC4 is a mem...
TMPY-04542	CDK2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinas...
TMPH-02217	SMARCA4 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic acti...
TMPH-01267	RNF13 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair protein...