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ターゲット

阻害剤

天然化合物

174

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
TP2137L	Pp60 c-src (521-533) (phosphorylated) acetate		Others
	pp60 c-src (521-533) (phosphorylated) acetate is a regulator of focal adhesion formation and cell spreading. pp60 c-src (521-533) (phosphorylated) acetate also regulates cell motility and is a key component in the signal...		Others
T39185	Pp60 (v-SRC) Autophosphorylation Site, Phosphorylated	pp60 (v-SRC) Autophosphorylation Site, Phosphorylated
	pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is a phosphorylated peptide derived from an EGFR substrate. It serves as a valuable tool for quantifying phosphorylated substrates in screening EGFR Kinase inhibitors...
TP1590	MARCKS Peptide(151-175), Phosphorylated
	Myristoylated Alanine-Rich C Kinase Substrate peptide (151-175) is a high affinity Protein Kinase C substrate.
TP2137	Pp60 c-src (521-533) (phosphorylated)
	Peptide corresponding to the pp60c-src carboxy terminal regulatory domain; phosphorylated at Tyr527. Binds to pp60c-src and pp60v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potenti...
T81578	P60c-src substrate II, phosphorylated
	Phosphorylated p60c-src substrate II is a pentapeptide and a phosphorylated polypeptide form of p60c-src substrate II. Phosphorylation is a critical post-translational modification (post-translationmodification) vital fo...
T3071	Olverembatinib	GZD 824	Bcr-Abl
	Olverembatinib (GZD 824) is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and Bcr-Abl(T315I, IC50: 0.68 nM).		Bcr-Abl
T7704	KY-226		Phosphatase
	KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM,)		Phosphatase
T2429	Olverembatinib dimesylate	GZD824 Dimesylate,HQP1351	Bcr-Abl
	Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).		Bcr-Abl
T31929	Giripladib	PLA 695,PLA-695,PLA695	Phospholipase
	Giripladib (PLA695)(PLX-695) is a cPLA2-specific inhibitor that inhibits the radiation-induced increase of phosphorylated ERK and phosphorylated Akt in endothelial cells.		Phospholipase
TP1789L	Malantide acetate(86555-35-3 free base)		PKA , PKC
	Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide that is phosphorylated by PKA and is used to measure PKA activ...		PKA , PKC
T26078	Rhodblock 6	Rhodblock6,Rhodblock-6	ROCK
	Rhodblock 6 is a Rho kinase (ROCK) inhibitor that inhibits the localization of phosphorylated MRLC (Myosin Regulatory Light Chain) and acts by specifically inhibiting Rho kinase activity.		ROCK
T67772	Phos-tag Acrylamide AAL-107
	Phos-tag Acrylamide AAL-107 is an acrylamide-pendant that can be used as a tool to visualize phosphorylated proteins.
T26193	SKLB-163	SKLB163	MAPK , Akt , Caspase , Rho , JNK
	SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.		MAPK , Akt , Caspase , Rho , JNK
T17205	UNC2541		Others , FLT , TAM Receptor
	UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM). UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).		Others , FLT , TAM Receptor
T14569	BI8626		E1/E2/E3 Enzyme
	BI8626 is a ubiquitin ligase HUWE1 inhibitor with protective effects against spontaneous desiccation syndrome in NOD/ShiLtj mice.BI8626 inhibits intracellular cholesterol and decreases the expression of phosphorylated ZA...		E1/E2/E3 Enzyme
T6762	AS1842856		Autophagy , FOXO1
	AS1842856, a cell-permeable inhibitor, can block the transcription activity of Foxo1 (IC50: 33 nM). It can directly bind to the active Foxo1, but not the Ser256-phosphorylated form.		Autophagy , FOXO1
T3438	S107		Others
	S107 is a RyR-selective 1, 4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.		Others
T7280	CAY10594		Phospholipase
	CAY10594 is a potent phospholipase D2(PLD2) inhibitor. CAY10594 ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis.		Phospholipase
T16961	Supinoxin	RX-5902	Apoptosis , DNA/RNA Synthesis
	Supinoxin (RX-5902) is an orally active inhibitor of phosphorylated-p68 RNA helicase and a potent first-in-class anti-cancer agent. Supinoxin induces cell apoptosis and inhibits the growth of TNBC cancer cell lines (IC50...		Apoptosis , DNA/RNA Synthesis
T15378L	Gemcitabine elaidate hydrochloride	CO-101 hydrochloride,Gemcitabine elaidate hydrochloride(210829-30-4(free base)),Gemcitabine 5'-elaidate hydrochloride,CP-4126 hydrochloride	Others
	Gemcitabine elaidate (CP-4126) hydrochloride is lipophilic pro-drug of Gemcitabine. Gemcitabine elaidate hydrochloride is converted to Gemcitabine by esterases in order to be phosphorylated. In contrast to gemcitabine, G...		Others
T1643	Penciclovir	BRL 39123,VSA 671	HCV Protease , Antifection , HSV
	Penciclovir (BRL 39123) is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subsequently converted by cellular kinases into the ...		HCV Protease , Antifection , HSV
T1790	Fosaprepitant dimeglumine	L785298,MK-0517,Fosaprepitant dimeglumine salt	Neurokinin receptor
	Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion...		Neurokinin receptor
T37207L	Cdk5 Substrate acetate		CDK
	Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau. Cdk5 Substrate aceta...		CDK
T9636	Dalpiciclib	SHR-6390	CDK
	Dalpiciclib (SHR-6390) is a highly selective, orally bioavailable, and comparable potency inhibitor of CDK4 and CKD6 with IC50s of 12.4 nM and 9.9 nM, respectively. Dalpiciclib exerts potent antitumor activity in esophag...		CDK
T27242	EF24	EF 24,EF-24,3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone	ERK , MEK , Caspase
	EF24 (3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone) treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral ...		ERK , MEK , Caspase
T6446	Clevudine	L-FMAU,Levovir	HBV , DNA/RNA Synthesis
	Clevudine (Levovir) is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The ...		HBV , DNA/RNA Synthesis
T6501	Fludarabine Phosphate	NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Fludarabine Phosphate (NSC 312887 Phosphate) is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidl...
T29731	Agrocinopine	Agrocinopine A
	Agrocinopine is an Opine phosphorylated sugar synthesized by crown gall tumors.
T27709	K67	K 67,K-67
	K67 is a specific inhibitor against the interaction between KEAP1 DC domain and S349-phosphorylated KIR of p62/SQSTM1.
TP1789	Malantide
	Malantide is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide that is phosphorylated by PKA and is used to measure PKA activity in v...
T27655	JG-48
	JG-48 is an inhibitor of Hsp70. JG-48 suppresses phosphorylated and total Tau in cells, endogenous Tau in neuroblastoma cells.
T40829	D-Erythritol 4-phosphate
	D-erythritol 4-phosphate is a phosphorylated component isolated from the hydrolysate.
T36944	Ara-G		Nucleoside Antimetabolite/Analog
	Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporate...		Nucleoside Antimetabolite/Analog
T40447	T-705RMP
	T-705RMP, the phosphorylated metabolite derived from T-705, demonstrates a limited inhibitory impact on the host cells' IMP dehydrogenase (IMPDH) activities, with an IC 50 value of 601 μM.
T22421	S107 hydrochloride		Others
	S107 hydrochloride, a RyR-selective 1,4-benzothiazepine derivative, could stabilize RyR2 channels via enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.		Others
T73179	HDAC-IN-50
	HDAC-IN-50, a potent, orally active inhibitor targeting both FGFR (Fibroblast Growth Factor Receptor) and HDAC (Histone Deacetylase), exhibits IC50 values of 0.18, 1.2, 0.46, 1.4, 1.3, 1.6, 2.6, 13 nM for FGFR1, FGFR2, F...
TP1716	Calmodulin-Dependent Protein Kinase II (281-309)	Calmodulin-Dependent Protein Kinase II 281-309
	Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).
T35652	2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
	2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be effi...
T37602	GSK 143
	Spleen tyrosine kinase (Syk) inhibitor (pIC50 = 7.5). Also inhibits phosphorylated Erk (pIC50 = 7.1). Decreases cell number and viability in chronic lymphocytic leukemia (CCL) cell lines. Liddle et al (2011) Discovery of...
T10407	Gartisertib	ATR inhibitor 2	ATM/ATR
	ATR inhibitor 2 is an orally active, ATP-competitive, and selective ATR inhibitor (Ki <150 pM) with antitumor activity. ATR inhibitor 2 potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (Chk1) phosphorylati...		ATM/ATR
T40566	2′-O-(2-Methoxyethyl)guanosine	2′-O-(2-Methoxyethyl)guanosine,2'-O-MOE-rG
	2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a modified nucleoside, can be enzymatically converted from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside by adenosine deaminase. However, this compound is not readily phos...
T73303	BTK-IN-17
	BTK-IN-17 is a selective, orally active inhibitor of Bruton's Tyrosine Kinase (BTK) with an inhibition concentration (IC50) value of 13.7 nM. It effectively reduces the expression of phosphorylated BTK at Tyrosine 223 (p...
T83052	Anti-inflammatory agent 60		NF-κB
	Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, and reduces iNOS, phosphorylated p65, and β-catenin expression in a concentration-dependent manner [1].		NF-κB
T62519	SW02
	SW02 is a potent ATPase activator of Hsp70 (EC50: 150 μM). SW02 is able to accumulate total tau and phosphorylated tau (pTau).
T76475	Casein Kinase II Substrate
	Casein Kinase II Substrate, a peptide substrate, is selectively phosphorylated by casein kinase II (CK2) [1].
T75809	2B-(SP) (TFA)
	2B-(SP) TFA, an eIF2B-based substrate, is efficiently phosphorylated by both α and β isoforms of Glycogen Synthase Kinase-3 (GSK-3) [1].
T75719	Akt/SKG Substrate Peptide TFA
	Akt/SKG Substrate Peptide TFA is a synthetic peptide designed as a substrate specifically for Akt/PKB and is not phosphorylated by p70S6K or MAPK1 [1].
TP1602	[pThr3]-CDK5 Substrate
	[pThr3]-CDK5 Substrate is an effective Phospho-Thr3CDK5 Substrate.[pThr3]-CDK5 Substrate is phosphorylated by CDK5 with a Km value of 6 µM[1].
TP1660	[pThr3]-CDK5 Substrate (TFA)
	[pThr3]-CDK5 Substrate TFA is an effective Phospho-Thr3CDK5 Substrate. [pThr3]-CDK5 Substrate is phosphorylated by CDK5 with a Km value of 6 µM.
T39874	GSK143 dihydrochloride
	GSK143 dihydrochloride is a highly selective, orally active inhibitor of spleen tyrosine kinase (SYK), exhibiting a pIC 50 value of 7.5. It effectively inhibits phosphorylated Erk (pErk) with a pIC 50 value of 7.1. The c...

Compounds

pp60 c-src (521-533) (phosphorylated) acetate

TP2137L

Synonym:

Target: Others

pp60 (v-SRC) Autophosphorylation Site, Phosphorylated

T39185

Synonym: pp60 (v-SRC) Autophosphorylation Site, Phosphorylated

Target:

MARCKS Peptide(151-175), Phosphorylated

TP1590

Synonym:

Target:

pp60 c-src (521-533) (phosphorylated)

TP2137

Synonym:

Target:

p60c-src substrate II, phosphorylated

Olverembatinib dimesylate

T2429

Synonym: GZD824 Dimesylate,HQP1351

Target: Bcr-Abl

Giripladib

T31929

Synonym: PLA 695,PLA-695,PLA695

Target: Phospholipase

Malantide acetate(86555-35-3 free base)

Synonym: Rhodblock6,Rhodblock-6

Target: ROCK

Phos-tag Acrylamide AAL-107

Target: MAPK, Akt, Caspase, Rho, JNK

UNC2541

T17205

Synonym:

Target: Others, FLT, TAM Receptor

BI8626

T14569

Synonym:

Target: E1/E2/E3 Enzyme

AS1842856

T6762

Synonym:

Target: Autophagy, FOXO1

Target: Phospholipase

Supinoxin

T16961

Synonym: RX-5902

Target: Apoptosis, DNA/RNA Synthesis

Gemcitabine elaidate hydrochloride

T15378L

Synonym: CO-101 hydrochloride,Gemcitabine elaidate hydrochloride(210829-30-4(free base)),Gemcitabine 5'-elaidate hydrochloride,CP-4126 hydrochloride

Target: Others

Penciclovir

T1643

Synonym: BRL 39123,VSA 671

Target: HCV Protease, Antifection, HSV

Fosaprepitant dimeglumine

T1790

Synonym: L785298,MK-0517,Fosaprepitant dimeglumine salt

Target: Neurokinin receptor

Cdk5 Substrate acetate

Synonym: EF 24,EF-24,3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone

Target: ERK, MEK, Caspase

Clevudine

T6446

Synonym: L-FMAU,Levovir

Target: HBV, DNA/RNA Synthesis

Fludarabine Phosphate

T6501

Synonym: NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Agrocinopine

T29731

Synonym: Agrocinopine A

D-Erythritol 4-phosphate

Target: Nucleoside Antimetabolite/Analog

Calmodulin-Dependent Protein Kinase II (281-309)

TP1716

Synonym: Calmodulin-Dependent Protein Kinase II 281-309

Target:

2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

Synonym: ATR inhibitor 2

Target: ATM/ATR

2′-O-(2-Methoxyethyl)guanosine

T40566

Synonym: 2′-O-(2-Methoxyethyl)guanosine,2'-O-MOE-rG

Anti-inflammatory agent 60

Casein Kinase II Substrate

Akt/SKG Substrate Peptide TFA

T75719

Synonym:

Target:

[pThr3]-CDK5 Substrate

TP1602

Synonym:

Target:

[pThr3]-CDK5 Substrate (TFA)

TP1660

Synonym:

Target:

GSK143 dihydrochloride

T39874

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T5113	L-GLUCOSE	L-(-)-Glucose	Others
	L-Glucose (L-(-)-Glucose) is an enantiomer of D-glucose. L-Glucose is not bioavailable to cells as an energy source because it cannot be phosphorylated by hexokinase.		Others
T5057	DL-O-Phosphoserine	DL-2-Amino-3-hydroxypropanoic acid 3-phosphate,O-PHOSPHO-L-SERINE,DL-SOP	Others , Endogenous Metabolite
	DL-O-Phosphoserine (DL-SOP), a normal metabolite in human biofluid, is an ester of serine and phosphoric acid. Serine is one of three amino acid residues that are commonly phosphorylated by kinases during cell signaling ...		Others , Endogenous Metabolite
T3262	Phosphocreatine disodium	Disodium phosphocreatine,Phosphocreatine disodium salt,Creatine phosphate disodium salt	Others , Endogenous Metabolite
	Phosphocreatine disodium (Phosphocreatine disodium salt) is a phosphorylated creatine molecule that serves as a rapidly mobilizable reserve of high-energy phosphates in muscle, skeletal, and brain.		Others , Endogenous Metabolite
T78473	Sphingosine (d17:1)	C17 Sphingosine
	Sphingosine (d17:1) (C17 Sphingosine) is a 17-carbon sphingolipid found in human skin that can be phosphorylated by sphingomyelin kinase.Sphingosine C-17 can be used as an internal standard to perform spectroscopic analy...
T4726	D-Glucose 6-phosphate sodium	G6P sodium salt,D-Glucose 6-phosphate sodium salt,Sodium Glucose-6-Phosphate	Others , Endogenous Metabolite
	In cells, D-Glucose 6-phosphate sodium (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at t...		Others , Endogenous Metabolite
T0894	Thiamine hydrochloride	Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,Thiamine chloride hydrochloride	Apoptosis , HBV , Endogenous Metabolite
	Thiamine hydrochloride (Vitamin B1) is the hydrochloride salt form of thiamine, a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Upon hydrolysis, Thiami...		Apoptosis , HBV , Endogenous Metabolite
T7989	Trimethyl phosphate		Others
	Trimethyl phosphate is an organophosphorus compound that is an inhibitor of enzymes that catalyze the hydrolysis of phosphorylated compounds. It has been used as a reactant in the synthesis of peptides and other proteins...		Others
T5079	Adenosine 5'-diphosphate sodium salt	Adenosine-5'-diphosphate trisodium salt,ADP sodium salt	Others , Endogenous Metabolite
	Adenosine 5'-diphosphate sodium salt (ADP sodium salt) is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for energy storage and is...		Others , Endogenous Metabolite
T5069	D-Glucose 6-phosphate potassium salt		Others
	In cells, D-Glucose 6-phosphate potassium salt (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P l...		Others
TL0008	Gigantol		Wnt/beta-catenin , Glucosidase
	Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells. Gigantol may be developed as a...		Wnt/beta-catenin , Glucosidase
T19263	D-Glucose 6-phosphate		Others
	D-glucose 6-phosphate is glucose that is phosphorylated on the carbon 6 hydroxyl group.		Others
T35415	α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)
	α-D-Glucose-1,6-bisphosphate is abis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate syntha...

天然物製品

L-GLUCOSE

T5113

Synonym: L-(-)-Glucose

Target: Others

DL-O-Phosphoserine

T5057

Synonym: DL-2-Amino-3-hydroxypropanoic acid 3-phosphate,O-PHOSPHO-L-SERINE,DL-SOP

Target: Others, Endogenous Metabolite

Phosphocreatine disodium

T3262

Synonym: Disodium phosphocreatine,Phosphocreatine disodium salt,Creatine phosphate disodium salt

Target: Others, Endogenous Metabolite

Sphingosine (d17:1)

T78473

Synonym: C17 Sphingosine

Target:

D-Glucose 6-phosphate sodium

T4726

Synonym: G6P sodium salt,D-Glucose 6-phosphate sodium salt,Sodium Glucose-6-Phosphate

Target: Others, Endogenous Metabolite

Thiamine hydrochloride

T0894

Synonym: Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,Thiamine chloride hydrochloride

Target: Apoptosis, HBV, Endogenous Metabolite

Adenosine 5'-diphosphate sodium salt

T5079

Synonym: Adenosine-5'-diphosphate trisodium salt,ADP sodium salt

Target: Others, Endogenous Metabolite

D-Glucose 6-phosphate potassium salt

Target: Wnt/beta-catenin, Glucosidase

D-Glucose 6-phosphate

T19263

Synonym:

Target: Others

α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)

T35415

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-03298	IL-6 Protein, Rat, Recombinant	Rat	E. coli
	Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. I...
TMPY-03238	IL-6 Protein, Mouse, Recombinant	Mouse	E. coli
	Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. I...
TMPY-03327	IL-6 Protein, Rhesus, Recombinant	Rhesus	E. coli
	Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. I...
TMPY-02603	STAT6 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6...
TMPY-00863	IL-6 Protein, Human, Recombinant	Human	E. coli
	Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. I...
TMPY-04572	MKK4 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is...
TMPY-02801	PHGDH Protein, Human, Recombinant (His)	Human	E. coli
	PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the ...
TMPY-01682	LILRB3/CD85a Protein, Human, Recombinant (His)	Human	HEK293
	Leukocyte immunoglobulin-like receptor subfamily B member 3, also known as Leukocyte immunoglobulin-like receptor 3, Immunoglobulin-like transcript 5, Monocyte inhibitory receptor HL9, CD85 antigen-like family member A, ...
TMPY-05494	LILRB3/CD85a Protein, Human, Recombinant (hFc)	Human	HEK293
	Leukocyte immunoglobulin-like receptor subfamily B member 3, also known as Leukocyte immunoglobulin-like receptor 3, Immunoglobulin-like transcript 5, Monocyte inhibitory receptor HL9, CD85 antigen-like family member A, ...
TMPY-01384	Endoglin/CD105 Protein, Human, Recombinant (His)	Human	HEK293
	Endoglin, also known as CD105, is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. Endoglin contains an RGD...
TMPY-04774	ALK-2/ACVR1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been...
TMPY-05427	CD19 Protein, Human, Recombinant (hFc)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01949	CD19 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01741	CD19 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05540	CD19 Protein, Mouse, Recombinant (His), Biotinylated	Mouse	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05530	CD19 Protein, Cynomolgus/Rhesus, Recombinant (His), Biotinylated	Cynomolgus,Rhesus	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05127	CD19 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01059	BMPR2 Protein, Human, Recombinant (His)	Human	HEK293
	The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin...
TMPY-03599	RPRD1B Protein, Human, Recombinant (His)	Human	HEK293
	RPRD1B, together with RPRD1A, can accompany RNAP II from promoter regions to 3'-untranslated regions during transcription in vivo, predominantly interact with phosphorylated RNAP II, and can reduce CTD S5- and S7-phospho...
TMPJ-00726	NEO Protein, K. pneumoniae, Recombinant	Klebsiella pneumoniae	E. coli
	Aminoglycoside 3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria. These ATP-dependent enzymes phosphorylate the 3'-hydr...
TMPH-03048	LpxA Protein, MenC, Recombinant (His)	MenB	E. coli
	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
TMPY-02592	Annexin VI/ANXA6 Protein, Human, Recombinant (His)	Human	E. coli
	Annexin A6, also known as ANXA6 or ANXAⅥ, belongs to a family of Ca2+-dependent membrane and phospholipid binding proteins. Members of this family have been implicated in membrane-related events along exocytotic and endo...
TMPJ-01050	GRB2 Protein, Human, Recombinant (His)	Human	E. coli
	As an adaptor protein, Growth Factor Receptor-Bound Protein 2 (GRB2) is involved in siganl transduction and consists of a central SH2 domain flanked by two SH3 domains. GRB2 associates with activated Tyr-phosphorylated E...
TMPH-02651	Fbxo3 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and ...
TMPH-02429	Fukutin Protein, Cynomolgus, Recombinant (His & Myc)	Cynomolgus	E. coli
	Catalyzes the transfer of CDP-ribitol to the distal N-acetylgalactosamine of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate str...
TMPH-01577	KRT18 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT...
TMPH-03452	NDPK Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	Yeast
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Require...
TMPH-02666	Fukutin Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Catalyzes the transfer of CDP-ribitol to the distal N-acetylgalactosamine of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate str...
TMPH-01703	CDC25C Protein, Human, Recombinant (His)	Human	E. coli
	Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly de...
TMPH-01329	FBXW7 Protein, Human, Recombinant (His)	Human	in vitro E. coli expression system
	Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds pho...
TMPY-02240	STAT1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate t...
TMPH-01777	TYK2 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Non-receptor kinase involved in various processes including cell growth, development, cell migration, innate and adaptive immunity. Plays both structural and catalytic roles in numerous cytokines and interferons signalin...
TMPH-01778	TYK2 Protein, Human, Recombinant (His)	Human	Baculovirus
	Non-receptor kinase involved in various processes including cell growth, development, cell migration, innate and adaptive immunity. Plays both structural and catalytic roles in numerous cytokines and interferons signalin...
TMPH-01752	Nestin/NES Protein, Human, Recombinant (His)	Human	Yeast
	Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cell...
TMPH-01020	BTN3A1 Protein, Human, Recombinant (Yeast, His)	Human	Yeast
	Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells ...
TMPH-00318	LpxD Protein, Burkholderia pseudomallei, Recombinant (His & Myc)	Burkholderia pseudomallei	E. coli
	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer mem...
TMPH-02218	JUN Protein, Human, Recombinant (His)	Human	Baculovirus
	Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signali...
TMPH-02219	JUN Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signali...
TMPH-01021	BTN3A1 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells ...
TMPH-03451	NDPK Protein, S. cerevisiae, Recombinant (E. coli, His)	Saccharomyces cerevisiae	E. coli
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Require...
TMPH-01578	KRT18 Protein, Human, Recombinant (His)	Human	HEK293
	Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT...
TMPH-00099	NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)	Arabidopsis thaliana	Yeast
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Plays a...
TMPH-00078	Beta-amylase 1, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc)	Arabidopsis thaliana	E. coli
	Beta-amylase activity. Can use p-nitrophenyl maltopentaoside (PNPG5) as substrate only in reduced form. Can play a minor role in the starch degradation and maltose metabolism in chloroplasts during the night. More active...
TMPH-01695	MLKL Protein, Human, Recombinant (His)	Human	Yeast
	Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Does not have protein kinase activity. Activated following phosphorylation by RIPK3, leading to homotrimerization, localizat...
TMPJ-00675	ZNHIT1 Protein, Human, Recombinant (His)	Human	E. coli
	ZNHIT1 belongs to the ZNHIT1 family and contains one HIT-type zinc finger. It can be phosphorylated on Thr by MAPK11 or MAPK14. ZNHIT1 is a component of the chromatin-remodeling SRCAP complex, which is composed of at lea...
TMPH-00079	Beta-amylase 3, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His)	Arabidopsis thaliana	E. coli
	Beta-amylase activity. No alpha-amylase activity. Involved in cold resistance. Mediates the accumulation of maltose upon freezing stress, thus contributing to the protection of the photosynthetic electron transport chain...
TMPJ-00520	NANS Protein, Human, Recombinant (His)	Human	E. coli
	Sialic Acid Synthase (NANS) is an enzyme that contains one AFP-like domain. NANS is ubiquitous and plays a role in the biosynthetic pathways of sialic acids. NANS produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-de...
TMPH-01088	CBX5 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphor...
TMPY-00487	PTPN9 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Protein tyrosine phosphatase non-receptor type 9 (PTPN9), also named PTP-MEG2, is an important member of the protein tyrosine phosphatase family that is involved in variety of human diseases.PTPN9 plays an important role...
TMPH-02274	JAK2 Protein, Human, Recombinant (His)	Human	E. coli
	Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cyto...
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