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天然化合物

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カタログ番号	製品名	別名	ターゲット
T40548	NH-3		Thyroid hormone receptor(THR)
	NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the selective thyromi-metic GC-1, NH-3 effectively inhibits the...		Thyroid hormone receptor(THR)
T21938	AS-041164		PI3K
	AS-041164 is a selective and orally active PI3Kγ isoform inhibitor(IC50 of 70 nM), and shows less activity against PI3Kα, PI3Kβ, and PI3Kδ (IC50s of 240 nM, 1.45 μM, and 1.70 μM, respectively). It has anti-inflammatory e...		PI3K
T8497	SX-682		CXCR
	SX-682 is a potent, selective and orally bioavailable inhibitor of CXCR1/2 ,has the potential to treat castration-resistant prostate cancer.		CXCR
T18064	Lenalidomide-Br		Ligand for E3 Ligase
	Lenalidomide-Br (Compound 41) is a derivative of Lenalidomide, which serves as a ligand for cereblon (CRBN) - an E3 ubiquitin ligase involved in protein recruitment. This compound, Lenalidomide-Br, can be conjugated to a...		Ligand for E3 Ligase
T26869	BMS-986122	BMS 986122	Opioid Receptor
	BMS-986122 (BMS 986122) is a positive allosteric modulator of μ-opioid receptors that increases β-arrestin recruitment stimulated by endomorphin 1 in U2OS-OPRM1 human osteosarcoma cells expressing μ-opioid receptors (EC5...		Opioid Receptor
T16850	SB-265610	GSK-CXCR2	CXCR
	SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and...		CXCR
T28073	MLS1547	MLS000051547,MLS 1547,MLS-1547	Dopamine Receptor
	MLS1547 (MLS000051547) is a highly efficacious agonist of G protein-biased dopamine D2 receptor with a Ki of 1.2 μM. MLS1547 stimulates D2R G protein-mediated signaling with EC50 of 0.37 μM in a calcium mobilization assa...		Dopamine Receptor
T14667	BLT-1		Others , HCV Protease
	BLT-1 is a scavenger receptor BI (SR-BI)inhibitor.		Others , HCV Protease
T4657	WHI-P97		JAK
	WHI-P97 is a rationally designed potent inhibitor of JAK-3. IC50 value: Target: JAK3 Treatment of mast cells with WHI-P97 inhibited the translocation of 5-lipoxygenase (5-LO) from the nucleoplasm to the nuclear membrane ...		JAK
T40028	(S,R,S)-AHPC		Ligand for E3 Ligase
	(S,R,S)-AHPC is a VHL ligand that used in the recruitment of the VHL protein.		Ligand for E3 Ligase
T40503	Thalidomide-5-methyl		Ligand for E3 Ligase
	Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein.		Ligand for E3 Ligase
T22021	ACHP	IKK-2 Inhibitor VIII	IκB/IKK
	ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects on IKK-α and IKK-β. ACHP has anti-HIV-1 activity and inhibits HIV-1 long terminal repeat (LTR)-driven gene expression thro...		IκB/IKK
T7329	C-178		STING
	C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells.		STING
T18831	Thalidomide-propargyl		Others , Ligand for E3 Ligase
	Thalidomide-propargyl, a Thalidomide-derived Cereblon ligand, facilitates the recruitment of Cereblon. It can be attached to the protein ligand via a linker, producing IMiD-containing PROTACs.		Others , Ligand for E3 Ligase
T7753	Thalidomide-O-COOH	Cereblon ligand 3,E3 ligase Ligand 3,TCE35031	Others , Ligand for E3 Ligase
	Thalidomide-O-COOH (Cereblon ligand 3) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTACs.		Others , Ligand for E3 Ligase
T77673	7-FluorotryptaMine HCl		GPR , Arrestin
	7-FluorotryptaMine HCl is a potent aromatic monoamine GPRC5A agonist that induces GPRC5A-mediated β-arrestin recruitment.7-FluorotryptaMine HCl can be used to study signalling pathways related to immunity and cancer.		GPR , Arrestin
TP1922L1	ELA-11 (human) acetate(1784687-32-6 free base)		Apelin receptor , Arrestin
	ELA-11 (human) acetate high affinity apelin receptor agonist (Ki = 14 nM). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro.		Apelin receptor , Arrestin
T9029	STING-IN-3	C-171	STING
	STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.		STING
T8412	(S,R,S)-AHPC	VH032-NH2,MDK7526,VHL ligand 1	Others , Ligand for E3 Ligase
	(S,R,S)-AHPC (VH032-NH2) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC is potential useful for the targeted degradation of the androgen receptor.		Others , Ligand for E3 Ligase
T39988	6'-GNTI dihydrochloride		Opioid Receptor , Akt
	6'-GNTI dihydrochloride is a κ-opioid receptor (KOR) agonist that favors activation of G-protein-mediated signaling over recruitment of β-aspirin 2. 6'-GNTI dihydrochloride only activates the Akt pathway in striatal neur...		Opioid Receptor , Akt
T13671	(S,R,S)-AHPC-Me hydrochloride	VHL ligand 2 hydrochloride,E3 ligase Ligand 1	Others , Ligand for E3 Ligase
	(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is a chemical compound utilized in the synthesis of ARV-771, an exceptionally potent BET protein degrader. This compound selectively degrades BET protein in cell...		Others , Ligand for E3 Ligase
T7755	Thalidomide 4-fluoride	E3 ligase Ligand 4	IRAK , Ligand for E3 Ligase
	Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) ...		IRAK , Ligand for E3 Ligase
T9291	Thalidomide-5-OH	2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione	Others , Ligand for E3 Ligase
	Thalidomide-5-OH (2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione) is the Thalidomide-based cereblon ligand that used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a link...		Others , Ligand for E3 Ligase
T17157	TRAF-STOP inhibitor 6877002	CD40-TRAF6 inhibitor	NF-κB
	TRAF-STOP inhibitor 6877002 (CD40-TRAF6 inhibitor), is a selective inhibitor of CD40-TRAF6 interaction. TRAF-STOP 6877002 reduces leukocyte recruitment, and reduces macrophage activation; reduces macrophage proliferation...		NF-κB
T13877	(S,S,S)-AHPC hydrochloride	(S,S,S)-VH032-NH2 hydrochloride	Ligand for E3 Ligase
	(S,S,S)-AHPC hydrochloride ((S,S,S)-VH032-NH2 hydrochloride) is a VHL amino building block, is a ligand used as a negative control for (S,R,S)-AHPC. It is the VH032-based VHL ligand used in the recruitment of the VHL pro...		Ligand for E3 Ligase
T76882	Talquetamab	JNJ-64407564,JNJ-7564	Dopamine Receptor
	Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody for multiple myeloma with antitumor activity that induces T-cell-mediated killing of GPRC5-expressing MM cells through T-cell recruitment and ...		Dopamine Receptor
T15611	JH-RE-06		DNA/RNA Synthesis
	JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interact...		DNA/RNA Synthesis
T18066	Lenalidomide-OH		Ligand for E3 Ligase
	Lenalidomide-OH is a ligand of cereblon (CRBN), serving as an analog to Lenalidomide for E3 ubiquitin ligase. It is utilized in the recruitment of CRBN protein. Additionally, Lenalidomide-OH can be conjugated to a protei...		Ligand for E3 Ligase
T17927	(S,R,S)-AHPC TFA	VH032-NH2 TFA,VHL ligand 1 TFA	Others , Ligand for E3 Ligase
	(S,R,S)-AHPC TFA (VHL ligand 1 TFA) (VH032-NH2 TFA) is a VH032-based ligand designed for von Hippel-Lindau (VHL) protein recruitment. This compound can be linked to protein ligands (e.g., BCR-ABL1) using a linker to crea...		Others , Ligand for E3 Ligase
T7752	(S,R,S)-AHPC-Me	VHL ligand 2,E3 ligase Ligand 1A	Ligand for E3 Ligase
	(S,R,S)-AHPC-Me (E3 ligase Ligand 1A) (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771. ARV-771 is a...		Ligand for E3 Ligase
T41231	GP 1a		Cannabinoid Receptor , PERK , Arrestin
	GP 1a is a potent agonist of cannabinoid receptor 2 (CB2) (EC50=7.1), as shown in cAMP, GTPγS and β-arrestin recruitment assays. GP 1a is approximately 30-fold more selective for CB2 receptors than CB1 receptors and incr...		Cannabinoid Receptor , PERK , Arrestin
T77579	JC2-11		IL Receptor , Dehydrogenase , ROS , Caspase , NOD-like Receptor (NLR) , AIM2
	JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical (NC) inflammatory vesicles by disrupting reactive oxygen sp...
T63790	Cbl-b-IN-3		E1/E2/E3 Enzyme
	Cbl-b-IN-3 is a potent proto-oncogene-B (CPL-B) inhibitor of casitas B-series lymphoma (ic50 < 1 nM). Cpl-b, a cyclic E3 ubiquitin protein ligase, is involved in the setting of T lymphocyte activation thresholds. Cpl-b n...		E1/E2/E3 Enzyme
T41068	P53R3		p53
	P53R3 is a potent reactivator of p53, effectively restoring sequence-specific DNA binding to several p53 hot spot mutants, namely p53 R175H, p53 R248W, and p53 R273H. This compound exhibits p53-dependent antiproliferativ...		p53
T71869	IMB-10
	IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.
T10926	CYT-1010		Others
	CYT-1010 is an mu-opioid receptor agonist. The EC50 for the inhibition of β-arrestin recruitment and cAMP production is 13.1 nM and 0.0053 nM, respectively.		Others
T10926L	CYT-1010 hydrochloride		Others
	CYT-1010 hydrochloride is an mu-opioid receptor agonist. The EC50 for β-arrestin recruitment and cAMP production inhibition were 13.1 nM and 0.0053 nM, respectively.		Others
T77951	Thalidomide-5-O-C4-NH2 hydrochloride
	Thalidomide-5-O-C4-NH2 hydrochloride, a cereblon ligand derived from Thalidomide, facilitates the recruitment of CRBN protein. It can be tethered to a ligand for protein recruitment through a linker, enabling the formati...
T39032	Pomalidomide-5-O-CH3	Pomalidomide-5-O-CH3
	Pomalidomide-5-O-CH3, a derivative of Pomalidomide, serves as a specific ligand for cereblon (CRBN) protein recruitment. It can be linked to the protein ligand to create a PROTAC.
T40897	Lenalidomide-4-aminomethyl
	Lenalidomide-4-aminomethyl is a CRBN ligand derived from Lenalidomide, which is utilized for the recruitment of CRBN protein. By linking Lenalidomide-4-aminomethyl to the ligand, a PROTAC can be formed.
T40283	Thalidomide-5,6-Cl
	Thalidomide-5,6-Cl, a derivative of Thalidomide, serves as a cereblon ligand for the recruitment of CRBN protein. It can be linked to a ligand for protein using a linker to form PROTACs.
T70983	Zoledronate disodium
	Zoledronate disodium is an inhibitor of osteoclastogenesis and macrophage recruitment, decreasing bone turnover and stabilizing the bone matrix, exhibiting diverse anti-tumor effects in osteosarcoma.
T39894	Thalidomide-4-C3-NH2 hydrochloride	Thalidomide-4-C3-NH2 hydrochloride
	Thalidomide-4-C3-NH2 hydrochloride is a Thalidomide-derived cereblon ligand utilized for the recruitment of CRBN protein. This compound can be linked to the ligand for protein using a linker to create PROTACs.
T14777	BRD5529		Others
	BRD5529 is a selective inhibitor of CARD9-E3 ubiquitin ligase TRIM62 protein-protein interaction (IC50: 8.6 μM). BRD5529 directly and selectively binds CARD9, disrupts TRIM62 recruitment, inhibits TRIM62-mediated ubiquit...		Others
T61371	CB1R Allosteric modulator 4
	CB1R Allosteric modulator 4 is an effective and positive modulator of cannabinoid type-1 (CB1R), exhibiting significant biological activity. This compound inhibits the production of cAMP and demonstrates strong β-arresti...
T38457	Lenalidomide-4-OH
	Lenalidomide-4-OH is a cereblon (CRBN) ligand derived from Lenalidomide, utilized in the recruitment of the CRBN protein. It can be conjugated to the protein ligand via a linker, facilitating the formation of PROTAC.
T77960	Thalidomide-5-O-C13-NH2 hydrochloride
	Thalidomide-5-O-C13-NH2 hydrochloride, a cereblon ligand derived from Thalidomide, facilitates the recruitment of CRBN protein. It is designed to conjugate with a ligand for protein recruitment through a linker, enabling...
T39599	Lenalidomide-C5-amido-Boc	Lenalidomide-C5-amido-Boc
	Lenalidomide-C5-amido-Boc is a Cereblon ligand derived from Lenalidomide, and serves in the recruitment of CRBN protein. It can be effectively linked to the protein ligand through a linker, resulting in the formation of ...
TP1922	ELA-11(human)	ELA-11 (human)
	High affinity apelin receptor agonist (Ki = 14 nM). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro.
T80972	TNH	TMP-NVOC linker-Halo
	TNH, a dimeric compound, possesses the ability to penetrate living cells and facilitate the recruitment of proteins into cellular structures [1].

Compounds

NH-3

T40548

Synonym:

Target: Thyroid hormone receptor(THR)

Target: Ligand for E3 Ligase

BMS-986122

T26869

Synonym: BMS 986122

Target: Opioid Receptor

Synonym: MLS000051547,MLS 1547,MLS-1547

Target: Dopamine Receptor

BLT-1

T14667

Synonym:

Target: Others, HCV Protease

Target: Ligand for E3 Ligase

Thalidomide-5-methyl

T40503

Synonym:

Target: Ligand for E3 Ligase

ACHP

T22021

Synonym: IKK-2 Inhibitor VIII

Thalidomide-propargyl

T18831

Synonym:

Target: Others, Ligand for E3 Ligase

Thalidomide-O-COOH

T7753

Synonym: Cereblon ligand 3,E3 ligase Ligand 3,TCE35031

Target: Others, Ligand for E3 Ligase

7-FluorotryptaMine HCl

T77673

Synonym:

Target: GPR, Arrestin

ELA-11 (human) acetate(1784687-32-6 free base)

TP1922L1

Synonym:

Target: Apelin receptor, Arrestin

Synonym: VH032-NH2,MDK7526,VHL ligand 1

Target: Others, Ligand for E3 Ligase

6'-GNTI dihydrochloride

T39988

Synonym:

Target: Opioid Receptor, Akt

(S,R,S)-AHPC-Me hydrochloride

T13671

Synonym: VHL ligand 2 hydrochloride,E3 ligase Ligand 1

Target: Others, Ligand for E3 Ligase

Thalidomide 4-fluoride

T7755

Synonym: E3 ligase Ligand 4

Target: IRAK, Ligand for E3 Ligase

Thalidomide-5-OH

T9291

Synonym: 2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione

Target: Others, Ligand for E3 Ligase

TRAF-STOP inhibitor 6877002

T17157

Synonym: CD40-TRAF6 inhibitor

Target: NF-κB

(S,S,S)-AHPC hydrochloride

T13877

Synonym: (S,S,S)-VH032-NH2 hydrochloride

Target: Ligand for E3 Ligase

Talquetamab

T76882

Synonym: JNJ-64407564,JNJ-7564

Target: Dopamine Receptor

JH-RE-06

T15611

Synonym:

Target: DNA/RNA Synthesis

Lenalidomide-OH

T18066

Synonym:

Target: Ligand for E3 Ligase

(S,R,S)-AHPC TFA

T17927

Synonym: VH032-NH2 TFA,VHL ligand 1 TFA

Target: Others, Ligand for E3 Ligase

(S,R,S)-AHPC-Me

T7752

Synonym: VHL ligand 2,E3 ligase Ligand 1A

Target: Ligand for E3 Ligase

GP 1a

T41231

Synonym:

Target: Cannabinoid Receptor, PERK, Arrestin

JC2-11

T77579

Synonym:

Target: IL Receptor, Dehydrogenase, ROS, Caspase, NOD-like Receptor (NLR), AIM2

Cbl-b-IN-3

T63790

Synonym:

Target: E1/E2/E3 Enzyme

CYT-1010 hydrochloride

T10926L

Synonym:

Target: Others

Thalidomide-5-O-C4-NH2 hydrochloride

Synonym: Pomalidomide-5-O-CH3

Target:

Lenalidomide-4-aminomethyl

Thalidomide-4-C3-NH2 hydrochloride

T39894

Synonym: Thalidomide-4-C3-NH2 hydrochloride

CB1R Allosteric modulator 4

Thalidomide-5-O-C13-NH2 hydrochloride

T77960

Synonym:

Target:

Lenalidomide-C5-amido-Boc

T39599

Synonym: Lenalidomide-C5-amido-Boc

Target:

ELA-11(human)

TP1922

Synonym: ELA-11 (human)

Target:

TNH

T80972

Synonym: TMP-NVOC linker-Halo

Target:

カタログ番号	製品名	ターゲット
T4953	Neotuberostemonine	NOS
	Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruit...	NOS
TN6458	Acetylshikonin
	Acetylshikonin can effectively inhibit tumor cells, it can be used to treat hepatocellular carcinoma cells expressing hepatitis B virus X protein (HBX) by inducing ER stress , an oncoprotein from hepatitis B virus. Acety...

天然物製品

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00562	PDGF-BB Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P...
TMPY-02953	TEM8/ANTXR1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are ser...
TMPY-05176	AMH Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and ...
TMPY-04483	IRAK4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPJ-01213	ASXL1 Protein, Human, Recombinant (GST)	Human	E. coli
	Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma...
TMPH-02227	ERG Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure. ERG Protein, Human, Recombina...
TMPK-00876	G-CSFR/CD114 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The Granulocyte Colony-Stimulating Factor (G-CSF) receptor, a member of the hematopoietin cytokine receptor superfamily, functions as a homodimer and requires the recruitment of cytosolic protein tyrosine kinases (PTKs) ...
TMPH-01106	CD300LB Protein, Human, Recombinant (His)	Human	E. coli
	Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2. CD300LB Protein, Human, Recombinant (His) is expressed in E. coli expression ...
TMPY-03343	EIF3K Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	EIF3K is a member of the eIF3 subunit K family. It is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-...
TMPJ-01328	ZBP1 Protein, Human, Recombinant (His)	Human	E. coli
	Z-DNA Binding Protein 1 (ZBP1) is a protein with 2 DRADA repeats. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow, and spleen. ZBP1 participates in the detection of vir...
TMPH-01313	EIF4G1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c...
TMPH-03526	Cap8A Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	E. coli
	May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate comp...
TMPH-03634	GRA3 Protein, Toxoplasma gondii, Recombinant (His)	Toxoplasma gondii	E. coli
	Direct host-parasite interaction occurs at the cytoplasmic faces of the parasitophorous vacuole membrane (PVM) and the host endoplasmic reticulum (ER) membrane via GRA3 and host CAMLG association. Direct insertion of GRA...
TMPJ-01132	NEDD8 Protein, Human, Recombinant	Human	E. coli
	Human NEDD8 shares 60% amino acid sequence identity to ubiquitin. The only known substrates of NEDD8 modification are the cullin subunits of SCF ubiquitin E3 ligases. The NEDDylation of cullins is critical for the recrui...
TMPH-03289	EIF3I Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates ...
TMPH-03288	EIF3I Protein, Rat, Recombinant (His)	Rat	Baculovirus Insect Cells
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates ...
TMPH-02835	PDGFD Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role ...
TMPH-02175	TAF5L Protein, Human, Recombinant (GST)	Human	E. coli
	Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex....
TMPY-00452	SBDS Protein, Mouse, Recombinant (His)	Mouse	E. coli
	The mutation of Shwachman-Bodian-Diamond syndrome (SBDS) gene has been proposed to be a major causative reason for SDS. Shwachman-Diamond syndrome (SDS) is a rare pediatric disease characterized by various systemic disor...
TMPH-02055	RBPMS Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 an...
TMPY-00518	SBDS Protein, Human, Recombinant (His)	Human	E. coli
	The mutation of Shwachman-Bodian-Diamond syndrome (SBDS) gene has been proposed to be a major causative reason for SDS. Shwachman-Diamond syndrome (SDS) is a rare pediatric disease characterized by various systemic disor...
TMPK-01031	MAdCAM-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of...
TMPH-01312	EIF4G1 Protein, Human, Recombinant (B2M & His & JD & Myc)	Human	E. coli
	Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c...
TMPH-01079	CLN5 Protein, Human, Recombinant (His)	Human	E. coli
	Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal memb...
TMPJ-00252	SIRP beta 1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Signal-regulatory protein beta-1 (SIRPB1, CD172b) is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glyco...
TMPK-00964	MAdCAM-1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of...
TMPH-02180	TTBK2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Serine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother cent...
TMPK-00177	LAIR1 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that pla...
TMPK-00966	MAdCAM-1 Protein, Human, Recombinant (aa 19-317, His)	Human	HEK293 Cells
	Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of...
TMPY-03341	ASF1B Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	The histone chaperone anti-silencing factor 1a (ASF1a) interacts with MDC1 and is recruited to sites of DSBs to facilitate the interaction of phospho-ATM with MDC1 and phosphorylation of MDC1, which are required for the ...
TMPK-00965	MAdCAM-1 Protein, Human, Recombinant (aa 19-317, hFc)	Human	HEK293 Cells
	Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of...
TMPJ-01133	NEDD8 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Human NEDD8 shares 60% amino acid sequence identity to ubiquitin. The only known substrates of NEDD8 modification are the cullin subunits of SCF ubiquitin E3 ligases. The NEDDylation of cullins is critical for the recrui...
TMPY-00564	MCP-4 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. CCL13/MCP-4, is a CC family ...
TMPH-02217	SMARCA4 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic acti...
TMPH-01388	GCKR Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Regulates glucokinase (GCK) by forming an inactive complex with this enzyme. Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a me...
TMPH-02105	ASH2L Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 ...
TMPH-02211	TLR7 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Endosomal receptor that plays a key role in innate and adaptive immunity. Controls host immune response against pathogens through recognition of uridine-containing single strand RNAs (ssRNAs) of viral origin or guanosine...
TMPH-01267	RNF13 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair protein...
TMPJ-00419	CD16b Protein, Human, Recombinant (hFc & His)	Human	HEK293 Cells
	Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like...
TMPH-01387	GCKR Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Regulates glucokinase (GCK) by forming an inactive complex with this enzyme. Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a me...
TMPJ-01323	NTAL Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is invol...
TMPJ-00612	PSGL-1/CD162 Protein, Mouse, Recombinant (aa 42-307, hFc)	Mouse	HEK293 Cells
	P-selectin glycoprotein ligand 1 is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. As such, it plays a critical role in the tethering of these cells to activat...
TMPH-00533	T7 RNA polymerase Protein, Enterobacteria phage T7, Recombinant (His & Myc)	Escherichia phage T7	E. coli
	Highly processive DNA-dependent RNA polymerase that catalyzes the transcription of class II and class III viral genes. Recognizes a specific promoter sequence and enters first into an 'abortive phase' where very short tr...
TMPJ-01040	MAX Protein, Human, Recombinant (His)	Human	E. coli
	Myc-Associated Factor X (MAX) is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It contains 1 basic helix-loop-helix (bHLH) domain. It is found in the brain, heart, and lun...
TMPH-02301	VPS35 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transm...
TMPJ-00467	Mindin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Spondin-2, also referred to as mindin, belongs to the F-spondin family of secreted extracellular matrix proteins. Spondins are characterised by the presence of F-spondin domains 1 and 2 (FS1 and FS2) at the N-terminus an...
TMPH-02249	TRIM72 Protein, Human, Recombinant (E. coli, His & Myc)	Human	E. coli
	Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon mem...
TMPJ-00914	YY1 Protein, Human, Recombinant (His)	Human	E. coli
	Transcriptional repressor protein YY1（YY1）contains 4 C2H2-type zinc fingers and belongs to the YY transcription factor family. Multifunctional transcription factor exhibits positive and negative control on a large number...
TMPH-02212	TLR8 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Endosomal receptor that plays a key role in innate and adaptive immunity. Controls host immune response against pathogens through recognition of RNA degradation products specific to microorganisms that are initially proc...
TMPY-00517	LSP1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LSP1 (Lymphocyte Specific Protein 1) is a Protein Coding gene. This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regula...
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