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シグナル伝達経路 血管新生 アポトーシス オートファジー 細胞周期・チェックポイント クロマチン・エピジェネティック 細胞骨格シグナル
DNA損傷・DNA修復 内分泌・ホルモン GPCR/Gタンパク質 免疫・炎症 JAK・STATシグナル MAPK 膜輸送体・イオンチャネル
代謝 微生物学・ウィルス学 神経科学 NF-Κb 酸化還元 PI3K/Akt/mTORシグナル プロテアーゼ・プロテアソーム
幹細胞 チロシンキナーゼ・アダプター ユビキチン その他 PROTAC
生物活性化合物ライブラリー ゼネラルバイオウアクティヴライブラリー 承認/再開発 医薬品ライブラリー 疾患別 化合物ライブラリー 標的/経路別 化合物ライブラリー 特徴的な生物活性化合物ライブラリー
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ドラッグライク 化合物ライブラリー ドラッグライクライブラリー
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Search Results for " CRC "

ターゲット

Others

37

阻害剤

4

天然化合物

56

リコンビナントタンパク質

2

ライブラリー

カタログ番号 製品名 別名 ターゲット
T10309 Amphethinile Amphetinile,CRC 82-07 Others
T29168 XR-5000 NSC-601316,CRC8805,SN-22995,DACA,CRC-8805
XR-5000 is a DNA topoisomerase I and II inhibitor.
T40254 MRTX-1719 Histone Methyltransferase
MRTX-1719 is a potent, first-in-class, selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAP DEL SDMA cells.
T13176 TNO155 Batoprotafib Phosphatase
TNO155 is a protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; src homology region 2 domain phosphatase; PTPN11) inhibitor(IC50 : 0.011 µM),with potential antineoplastic activity.
T0459 Sulindac Arthrocine,MK-231,Clinoril,Sulindac sulfoxide COX , Autophagy
Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cycl...
T82324 GGASCCLYCRCH
GGASCCLYCRCH is a bioactive peptide that can inhibit the 2-O-methyltransferase activity within the SARS-CoV nsp16/10 complex.
T73593 PDS-0330 Others
PDS-0330 is a claudin-1 small molecule inhibitor inhibitor.PDS-0330 inhibits claudin-1-dependent CRC progression and binds directly and specifically to claudin-1 with micromolar affinity.PDS-0330 exhibits well characteri...
T77519 FC-116 FC116 Apoptosis , Microtubule Associated
FC-116 is a potent Tubulin inhibitor with antitumour activity and inhibits tumour growth in mice. FC-116 induces apoptosis in colorectal cancer (CRC) cells and promotes protein degradation.
T9901A-004 Labetuzumab IMMU-14,hMN-14,IMMU-100
Labetuzumab is a humanized anti-carcinoembryonic antigen (CEA) monoclonal antibody with anticancer activity that inhibits tumor growth and is used in the study of thyroid and colorectal cancer (CRC).
T72068 SFI003 Apoptosis , ROS
SFI003 is a novel SRSF3 inhibitor that exerts anticancer activity against colorectal cancer by modulating the SRSF3 / DHCR24 / ROS axis and driving apoptosis in CRC cells through the SRSF3 / DHCR24 / reactive oxygen spec...
T76890 Petosemtamab MCLA 158 EGFR
Petosemtamab (MCLA 158) is a highly potent monoclonal antibody against EGFR (Kd: 0.22 nM) and LGR5 (Kd: 0.86 nM). Petosemtamab promotes EGFR signaling disruption and receptor breakdown in LGR5+ cancer cells. Petosemtamab...
T9556 TNIK-IN-3 Wnt/beta-catenin
TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK). It exhibits a strong selectivity for TNIK with an IC50 value of 0.026 μM. Additionally, TNIK-IN-3 demonstrates...
T63049 CHD1Li 6.11 Others
CHD1Li 6.11 is a potent inhibitor of oncogenic CHD1L, acting on the cat-CHD1L recombinant protein (IC50: 3.3 μM). CHD1Li 6.11 is an orally active antitumour agent that significantly reduces the tumour volume of CRC xenog...
T41180 JQAD1 Epigenetic Reader Domain
JQAD1 is a potent and selective histone acetyltransferase EP300 degrader (PROTAC®; DC50≤ 31.6 nM); comprises an EP300 inhibitor, A485, joined by a linker to a cereblon E3 ligase ligand. JQAD1 brings about degradation of ...
T21567L Cyclosomatostatin Acetate Cyclosomatostatin Acetate （84211-54-1 Free base） Somatostatin
Cyclosomatostatin Acetate is an effective antagonist of the somatostatin receptor.Cyclosomatostatin Acetate inhibits SSTR1 signaling and decreases cell proliferation, ALDH+ cell population size, and sphere-formation in c...
T27163 DHNQ
DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).
T73391 BLM-IN-2
BLM-IN-2, a Bloom's Syndrome Protein (BLM) inhibitor, exhibits an IC50 of 0.8 μM and shows efficacy in suppressing proliferation, invasion, cell cycle arrest, and apoptosis in colorectal cancer (CRC) cells, making it a p...
T16406 Orvepitant maleate GW823296 maleate Neurokinin receptor
Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor). Orvepitant maleate has the potential for depressive disorder and chro...
T71624 GB1874
GB1874 inhibitor of the Wnt pathway that targets the β-cat-TCF4 PPI. GB1874 also affected the proliferation and stemness of Wnt-addicted colorectal cancer (CRC) cells in vitro. Encouragingly, GB1874 inhibited the growth...
T60030 NCT02
NCT02, a cyclin K degrader, promotes the ubiquitination and proteasomal degradation of cyclin K (CCNK) and its complex partner CDK12, showing promise for metastatic colorectal cancer (CRC) research[1].
T75842 Cyclosomatostatin TFA
Cyclosomatostatin TFA, a potent somatostatin (SST) receptor antagonist, inhibits type 1 somatostatin receptor (SSTR1) signaling, reducing cell proliferation, the size of the ALDH+ cell population, and sphere-formation in...
T36742 CDK5 inhibitor 20-223 CDK5 inhibitor 20-223
CDK5 inhibitor 20-223, a potent inhibitor of CDK2 and CDK5, demonstrates IC50 values of 6.0 nM and 8.8 nM, respectively. It serves as an effective agent against colorectal cancer (CRC)[1].
T70312 AZ1366
AZ1366 is a potent tankyrase inhibitor that enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance. Combination AZ1366 and irinotecan achieved greater anti-tumor effects compare...
T82414 Favezelimab MK-4280
Favezelimab (MK-4280) is a humanized anti-LAG-3 monoclonal antibody that inhibits the LAG-3/MHC class II interaction and shows potential for use in colorectal cancer (CRC) research, particularly when combined with the PD...
T39792 AMPC
AMPC, a powerful and efficient inhibitor of TFF3, demonstrates inhibitory effects on cell proliferation, survival, oncogenicity, and CSC-like behavior in TFF3-positive CMS4 CRC cells. It acts as a promising standalone an...
T61896 HCAIX-IN-12
hCAIX-IN-12 is an effective hCAIX inhibitor, IC50 for CAIX and CAII is 0.74 and 10.78 μM , respectively. hCAIX-IN-12 inhibits cell proliferation and induces apoptosis. HCAIX-IN-12 can increase the generation of ROS. HCAI...
T72355 KRAS G12D inhibitor 16
KRAS G12D Inhibitor 16 is a potent compound targeting the KRAS G12D and its mutation, exhibiting inhibitory activity with IC50 values of 0.7 nM and 0.35 μM, respectively. It is utilized in researching various malignant t...
T69985 Lifirafenib HCl
Lifirafenib, also known as Beigene-283, is a Novel potent and selective RAF Kinase and EGFR inhibitor. BGB-283-displays Potent Antitumor Activity in B-RAF Mutated Colorectal Cancers. In vitro, BGB-283 potently inhibits ...
T38519 YB-0158 Wnt pathway inhibitor 2,YB-0158
YB-0158 (Wnt pathway inhibitor 2) is a powerful peptidomimetic compound that effectively targets colorectal cancer stem cells (CSCs) by disrupting the interaction between Sam68 and Src proteins. This compound acts as a r...
T61585 Sulindac sodium
Sulindac (sodium) (MK-231) is an orally active nonsteroidal anti-inflammatory agent. Sulindac (sodium) is used to reduce pain, swelling, and joint stiffness from arthritis. Sulindac is also used for the research of arthr...
T21762 LDN-211904
LDN-211904 oxalate (compound 32), a potent and selective EphB3 inhibitor, demonstrates an IC50 of 0.079 μM and shows good metabolic stability in mouse liver microsomes. When combined with cetuximab, it may effectively in...
T78879 CXCR4-IN-2 CXCR
CXCR4-IN-2 (compound A1), a potent bifunctional fluorinated small molecule, inhibits CXCR4 and exhibits anticancer properties by exerting cytotoxicity (IC 50: 60 μg/mL; 72 h) and antiproliferative effects on mouse colore...
T35080 VU0456940 VU-0456940,VU 0456940
VU0456940 is a potent M1 PAM with excellent selectivity (hM1 EC50 = 340 nM, 14-fold leftward shift of the ACh CRC; hM2–hM5 inactive). VU0456940 potentiated the excitation of a subthreshold concentration of CCh in MSNs. V...
T36676 Rineterkib hydrochloride
Rineterkib hydrochloride (compound B) is an orally active RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly relat...
T78569 CPT2 Carnitine palmitoyltransferase 2 Apoptosis
Carnitine palmitoyltransferase 2 (CPT2), an enzyme involved in fatty acid oxidation, serves as a prognostic biomarker for colorectal cancer (CRC). Overexpression of CPT2 activates phosphorylated p53, enhancing its expres...
T63528 HSP90-IN-11
HSP90-IN-11 is a potent inhibitor of HSP90 and induces significant accumulation of the sub-G1 population. HSP90-IN-11 has a potent HSP90α inhibitory effect comparable to that of AUY-922 (Luminespib). In CRC and NSCLC cel...
T79226 AMPK activator 11 Mitochondrial Metabolism
AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-activated protein kinase (AMPK) and enhancement of oxidative...

Compounds

Amphethinile
T10309
Synonym: Amphetinile,CRC 82-07
Target: Others
XR-5000
T29168
Synonym: NSC-601316,CRC8805,SN-22995,DACA,CRC-8805
Target:
MRTX-1719
T40254
Synonym:
Target: Histone Methyltransferase
TNO155
T13176
Synonym: Batoprotafib
Target: Phosphatase
Sulindac
T0459
Synonym: Arthrocine,MK-231,Clinoril,Sulindac sulfoxide
Target: COX, Autophagy
GGASCCLYCRCH
T82324
Synonym:
Target:
PDS-0330
T73593
Synonym:
Target: Others
FC-116
T77519
Synonym: FC116
Target: Apoptosis, Microtubule Associated
Labetuzumab
T9901A-004
Synonym: IMMU-14,hMN-14,IMMU-100
Target:
SFI003
T72068
Synonym:
Target: Apoptosis, ROS
Petosemtamab
T76890
Synonym: MCLA 158
Target: EGFR
TNIK-IN-3
T9556
Synonym:
Target: Wnt/beta-catenin
CHD1Li 6.11
T63049
Synonym:
Target: Others
JQAD1
T41180
Synonym:
Target: Epigenetic Reader Domain
Cyclosomatostatin Acetate
T21567L
Synonym: Cyclosomatostatin Acetate （84211-54-1 Free base）
Target: Somatostatin
DHNQ
T27163
Synonym:
Target:
BLM-IN-2
T73391
Synonym:
Target:
Orvepitant maleate
T16406
Synonym: GW823296 maleate
Target: Neurokinin receptor
GB1874
T71624
Synonym:
Target:
NCT02
T60030
Synonym:
Target:
Cyclosomatostatin TFA
T75842
Synonym:
Target:
CDK5 inhibitor 20-223
T36742
Synonym: CDK5 inhibitor 20-223
Target:
AZ1366
T70312
Synonym:
Target:
Favezelimab
T82414
Synonym: MK-4280
Target:
AMPC
T39792
Synonym:
Target:
hCAIX-IN-12
T61896
Synonym:
Target:
KRAS G12D inhibitor 16
T72355
Synonym:
Target:
Lifirafenib HCl
T69985
Synonym:
Target:
YB-0158
T38519
Synonym: Wnt pathway inhibitor 2,YB-0158
Target:
Sulindac sodium
T61585
Synonym:
Target:
LDN-211904
T21762
Synonym:
Target:
CXCR4-IN-2
T78879
Synonym:
Target: CXCR
VU0456940
T35080
Synonym: VU-0456940,VU 0456940
Target:
Rineterkib hydrochloride
T36676
Synonym:
Target:
CPT2
T78569
Synonym: Carnitine palmitoyltransferase 2
Target: Apoptosis
HSP90-IN-11
T63528
Synonym:
Target:
AMPK activator 11
T79226
Synonym:
Target: Mitochondrial Metabolism
カタログ番号 製品名 別名 ターゲット
T6212 Combretastatin A4 CA4,CRC 87-09 Microtubule Associated
Combretastatin A4 (CA4) is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM).
T3055 Liensinine Perchlorate Apoptosis , Others
Liensinine is the active constituent of plumula nelambinis with anti-hypertension.
T4S1551 Cinnamaldehyde Cinnamic Aldehyde HIF
1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the express...
T79933 (−)-N-Hydroxyapiosporamide NHAP NF-κB
(−)-N-Hydroxyapiosporamide (NHAP), an alkaloid, serves as an NF-κB inhibitor and demonstrates significant antitumor activity both in vitro and in vivo. It has potential applications in colorectal cancer (CRC) research [1...

天然物製品

Combretastatin A4
T6212
Synonym: CA4,CRC 87-09
Target: Microtubule Associated
Liensinine Perchlorate
T3055
Synonym:
Target: Apoptosis, Others
Cinnamaldehyde
T4S1551
Synonym: Cinnamic Aldehyde
Target: HIF
(−)-N-Hydroxyapiosporamide
T79933
Synonym: NHAP
Target: NF-κB

Recombinant Proteins

Species：
Human (35)
Mouse (12)
Cynomolgus (5)
Canine (3)
Human (1)
Expression System：
HEK293 (42)
E. coli (10)
Baculovirus-Insect Cells (3)
Baculovirus (1)
Tag：
His (16)
C-His (10)
hFc (7)
GST (3)
Tag Free (3)
mFc (3)
C-His-Avi (2)
C-hFc (2)
N-6His (2)
His (1)
カタログ番号 製品名 Species Expression System
TMPY-00365 GALNT7 Protein, Human, Recombinant (His) Human HEK293
GalNAc-transferase-7 (GALNT7) is essential for the regulation of cell proliferation and has been implicated in tumorigenesis. Colorectal cancer (CRC) arises in a multistep molecular network process, which is from either ...
TMPY-04722 DcR1/TRAILR3 Protein, Human, Recombinant (His) Human HEK293
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most ...
TMPY-02575 PPAR gamma/PPARG Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling even...
TMPY-04508 IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc) Mouse HEK293
Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IG...
TMPY-02533 IGFBP-7 Protein, Human, Recombinant (aa 30-282, His) Human HEK293
Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IG...
TMPY-02295 IGFBP-7 Protein, Human, Recombinant (aa 1-282, hFc) Human HEK293
Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IG...
TMPY-00779 DPP4/CD26 Protein, Human, Recombinant Human HEK293
Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the...
TMPY-00221 DPP4/CD26 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the...
TMPY-00778 DPP4/CD26 Protein, Human, Recombinant (hFc) Human HEK293
Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the...
TMPY-00122 DPP4/CD26 Protein, Human, Recombinant (His) Human HEK293
Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the...
TMPK-00669 SFRP2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
As biomarkers, DNA methylation is used to detect colorectal cancer (CRC) and make assessment of CRC prognosis. The published findings showed the association between the methylation of SFRP1, SFRP2, and WIF1, located in t...
TMPK-00898 EphB3 Protein, Human, Recombinant (His) Human HEK293
Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC compared to normal mucosa. Hypermethylation of CpG island is co...
TMPK-01124 TEM1/CD248 Protein, Mouse, Recombinant (His) Mouse HEK293
Colorectal cancer (CRC) is one of the most common cancers worldwide usually diagnosed in the advanced stage. The serum concentration of tumor endothelial marker 1 (TEM1) was measured and correlated with clinicopathologic...
TMPK-01142 SFRP2 Protein, Human, Recombinant (His) Human HEK293
As biomarkers, DNA methylation is used to detect colorectal cancer (CRC) and make assessment of CRC prognosis. The published findings showed the association between the methylation of SFRP1, SFRP2, and WIF1, located in t...
TMPK-00445 VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi) Human HEK293
Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly ...
TMPK-00446 VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated Human HEK293
Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly ...
TMPH-02219 JUN Protein, Human, Recombinant (His & Myc) Human E. coli
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signali...
TMPH-02218 JUN Protein, Human, Recombinant (His) Human Baculovirus
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signali...
TMPK-01332 LY6G6D Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utiliz...
TMPK-00753 LY6G6D Protein, Human, Recombinant (His) Human HEK293
LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utiliz...
TMPK-00754 LY6G6D Protein, Human, Recombinant (His & Strep-II) Human HEK293
LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utiliz...
TMPK-00992 SEZ6L2 Protein, Mouse, Recombinant (His) Mouse HEK293
Seizure-related 6 homolog (mouse)-like 2 (SEZ6L2) was shown to be involved in transcription of a type 1 transmembrane protein for regulating cell fate. SEZ6L2 was significantly up-regulated in tumour tissues of patients ...
TMPK-01321 TEM1/CD248 Protein, Canine, Recombinant (His) Canine HEK293
Colorectal cancer (CRC) is one of the most common cancers worldwide usually diagnosed in the advanced stage. The serum concentration of tumor endothelial marker 1 (TEM1) was measured and correlated with clinicopathologic...
TMPK-01191 TEM1/CD248 Protein, Human, Recombinant (His) Human HEK293
Colorectal cancer (CRC) is one of the most common cancers worldwide usually diagnosed in the advanced stage. The serum concentration of tumor endothelial marker 1 (TEM1) was measured and correlated with clinicopathologic...
TMPY-00497 ZG16 Protein, Human, Recombinant (mFc) Human HEK293
Zymogen granule protein 16 (ZG16) is one of the most significantly down-regulated genes in colorectal cancer (CRC) tissues. Proteomic analyses of mucus have identified the lectin-like protein ZG16 as an abundant mucus co...
TMPY-03989 PFDN1 Protein, Human, Recombinant (His) Human E. coli
PFDN1 expression positively correlated with tumor size and tumor invasion. The inhibitory effect of PFDN1 on tumor cell growth and motility was partially due to G2/M cell cycle blockage and cytoskeletal deficiency. PFDN1...
TMPY-02046 PFDN1 Protein, Mouse, Recombinant (His) Mouse E. coli
PFDN1 expression positively correlated with tumor size and tumor invasion. The inhibitory effect of PFDN1 on tumor cell growth and motility was partially due to G2/M cell cycle blockage and cytoskeletal deficiency. PFDN1...
TMPY-03859 DHRS9 Protein, Human, Recombinant (His) Human E. coli
Dehydrogenase/reductase (SDR family) member 9 (DHRS9) is aberrantly expressed in colorectal cancer (CRC), the decreased expression of DHRS9 correlates with tumor progression and may serve as a potential prognostic bioma...
TMPK-00752 LY6G6D Protein, Human, Recombinant (hFc) Human HEK293
LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utiliz...
TMPK-01323 CEACAM1 Protein, Canine, Recombinant (His) Canine HEK293
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM-1) is the major antigen of the CD66 cluster of granulocyte differentiation antigens. The present study aimed to assess the biological function of CEACAM-1...
TMPK-00869 CEACAM1 Protein, Mouse, Recombinant (aa 35-428, His) Mouse HEK293
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM-1) is the major antigen of the CD66 cluster of granulocyte differentiation antigens. The present study aimed to assess the biological function of CEACAM-1...
TMPY-02398 TLE3 Protein, Human, Recombinant (aa 484-772, GST) Human E. coli
The association between high TLE3 expression and a favorable response to taxane-containing chemotherapy regimens was validated in patients with non-serous ovarian cancer. That TLE3 expression may serve as a marker of che...
TMPY-05168 Syndecan-2 Protein, Mouse, Recombinant (His) Mouse HEK293
The key players in the miR-20a-5p/SDC2 axis may be a potential diagnostic biomarker and therapeutic target for OS patients. SDC2 methylation as a blood-based DNA test for early detection of colorectal cancer (CRC).
TMPY-04249 Syndecan-2 Protein, Human, Recombinant (His) Human HEK293
The key players in the miR-20a-5p/SDC2 axis may be a potential diagnostic biomarker and therapeutic target for OS patients. SDC2 methylation as a blood-based DNA test for early detection of colorectal cancer (CRC).
TMPY-00025 Mammaglobin B/SCGB2A1 Protein, Human, Recombinant (hFc) Human HEK293
SCGB2A1 represented a novel, prognostic factor for CRC, and that expression of SCGB2A1 correlated with chemoresistance, radioresistance and cancer cell stemness. SCGB2A1 is a top differentially expressed gene in all majo...
TMPY-04686 SHISA3 Protein, Human, Recombinant (mFc) Human HEK293
SHISA3(high)CLL are characterized by a restrained activation of Wnt signaling and sensibility to lenalidomide-induced apoptosis. SHISA3 promoter hypermethylation might increase the risk of LSCC through regulation of gene...
TMPK-01045 IL-20RA Protein, Mouse, Recombinant (hFc) Mouse HEK293
IL-20RA was highly expressed in the tumor tissue of CRC and related to the advanced stage.IL-20RA was involved in regulating oncogenic and immune pathways and affecting the expression of genes related to cell proliferati...
TMPY-04084 ANGPTL1 Protein, Canine, Recombinant (hFc) Canine HEK293
Angiopoietin-like protein 1 (ANGPTL1) has been reported to suppress migration and invasion in lung and breast cancer, acting as a novel tumor suppressor candidate. Downregulation of tumor suppressor signaling plays an im...
TMPY-04271 Frizzled 6 Protein, Human, Recombinant (His) Human HEK293
FZD6 plays a pivotal role in the growth and guidance of the nail plate in humans by acting as a molecular switch between different Wnt pathways. Inherited isolated nail anomaly manifesting with onychauxis and onycholysis...
TMPY-00577 Frizzled 6 Protein, Human, Recombinant (mFc) Human HEK293
FZD6 plays a pivotal role in the growth and guidance of the nail plate in humans by acting as a molecular switch between different Wnt pathways. Inherited isolated nail anomaly manifesting with onychauxis and onycholysis...
TMPY-06848 IGFBP-7 Protein, Human, Recombinant (K95R, His) Human HEK293
Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IG...
TMPY-02296 IGFBP-7 Protein, Human, Recombinant (aa 1-282, His) Human HEK293
Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IG...
TMPY-06649 IGFBP-7 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IG...
TMPY-06644 IGFBP-7 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IG...
TMPY-06879 IGFBP-7 Protein, Mouse, Recombinant (aa 26-281, His) Mouse HEK293
Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IG...
TMPY-01268 SMYD3 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger...
TMPU-00001 KRAS Protein, Human, Recombinant (G12S, GST) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. As other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes becau...
TMPY-02770 CCL20 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family that attracts immature dendriti...
TMPY-04889 CCL20 Protein, Mouse, Recombinant Mouse E. coli
Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family that attracts immature dendriti...
TMPJ-00510 KRAS Protein, Human, Recombinant (G12C, His) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. As other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes becau...
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GALNT7 Protein, Human, Recombinant (His)
TMPY-00365
Species: Human
Expression System: HEK293
DcR1/TRAILR3 Protein, Human, Recombinant (His)
TMPY-04722
Species: Human
Expression System: HEK293
PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)
TMPY-02575
Species: Human
Expression System: Baculovirus-Insect Cells
IGFBP-7 Protein, Mouse, Recombinant (aa 1-281, hFc)
TMPY-04508
Species: Mouse
Expression System: HEK293
IGFBP-7 Protein, Human, Recombinant (aa 30-282, His)
TMPY-02533
Species: Human
Expression System: HEK293
IGFBP-7 Protein, Human, Recombinant (aa 1-282, hFc)
TMPY-02295
Species: Human
Expression System: HEK293
DPP4/CD26 Protein, Human, Recombinant
TMPY-00779
Species: Human
Expression System: HEK293
DPP4/CD26 Protein, Mouse, Recombinant (hFc)
TMPY-00221
Species: Mouse
Expression System: HEK293
DPP4/CD26 Protein, Human, Recombinant (hFc)
TMPY-00778
Species: Human
Expression System: HEK293
DPP4/CD26 Protein, Human, Recombinant (His)
TMPY-00122
Species: Human
Expression System: HEK293
SFRP2 Protein, Cynomolgus, Recombinant (His)
TMPK-00669
Species: Cynomolgus
Expression System: HEK293
EphB3 Protein, Human, Recombinant (His)
TMPK-00898
Species: Human
Expression System: HEK293
TEM1/CD248 Protein, Mouse, Recombinant (His)
TMPK-01124
Species: Mouse
Expression System: HEK293
SFRP2 Protein, Human, Recombinant (His)
TMPK-01142
Species: Human
Expression System: HEK293
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi)
TMPK-00445
Species: Human
Expression System: HEK293
VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated
TMPK-00446
Species: Human
Expression System: HEK293
JUN Protein, Human, Recombinant (His & Myc)
TMPH-02219
Species: Human
Expression System: E. coli
JUN Protein, Human, Recombinant (His)
TMPH-02218
Species: Human
Expression System: Baculovirus
LY6G6D Protein, Cynomolgus, Recombinant (His)
TMPK-01332
Species: Cynomolgus
Expression System: HEK293
LY6G6D Protein, Human, Recombinant (His)
TMPK-00753
Species: Human
Expression System: HEK293
LY6G6D Protein, Human, Recombinant (His & Strep-II)
TMPK-00754
Species: Human
Expression System: HEK293
SEZ6L2 Protein, Mouse, Recombinant (His)
TMPK-00992
Species: Mouse
Expression System: HEK293
TEM1/CD248 Protein, Canine, Recombinant (His)
TMPK-01321
Species: Canine
Expression System: HEK293
TEM1/CD248 Protein, Human, Recombinant (His)
TMPK-01191
Species: Human
Expression System: HEK293
ZG16 Protein, Human, Recombinant (mFc)
TMPY-00497
Species: Human
Expression System: HEK293
PFDN1 Protein, Human, Recombinant (His)
TMPY-03989
Species: Human
Expression System: E. coli
PFDN1 Protein, Mouse, Recombinant (His)
TMPY-02046
Species: Mouse
Expression System: E. coli
DHRS9 Protein, Human, Recombinant (His)
TMPY-03859
Species: Human
Expression System: E. coli
LY6G6D Protein, Human, Recombinant (hFc)
TMPK-00752
Species: Human
Expression System: HEK293
CEACAM1 Protein, Canine, Recombinant (His)
TMPK-01323
Species: Canine
Expression System: HEK293
CEACAM1 Protein, Mouse, Recombinant (aa 35-428, His)
TMPK-00869
Species: Mouse
Expression System: HEK293
TLE3 Protein, Human, Recombinant (aa 484-772, GST)
TMPY-02398
Species: Human
Expression System: E. coli
Syndecan-2 Protein, Mouse, Recombinant (His)
TMPY-05168
Species: Mouse
Expression System: HEK293
Syndecan-2 Protein, Human, Recombinant (His)
TMPY-04249
Species: Human
Expression System: HEK293
Mammaglobin B/SCGB2A1 Protein, Human, Recombinant (hFc)
TMPY-00025
Species: Human
Expression System: HEK293
SHISA3 Protein, Human, Recombinant (mFc)
TMPY-04686
Species: Human
Expression System: HEK293
IL-20RA Protein, Mouse, Recombinant (hFc)
TMPK-01045
Species: Mouse
Expression System: HEK293
ANGPTL1 Protein, Canine, Recombinant (hFc)
TMPY-04084
Species: Canine
Expression System: HEK293
Frizzled 6 Protein, Human, Recombinant (His)
TMPY-04271
Species: Human
Expression System: HEK293
Frizzled 6 Protein, Human, Recombinant (mFc)
TMPY-00577
Species: Human
Expression System: HEK293
IGFBP-7 Protein, Human, Recombinant (K95R, His)
TMPY-06848
Species: Human
Expression System: HEK293
IGFBP-7 Protein, Human, Recombinant (aa 1-282, His)
TMPY-02296
Species: Human
Expression System: HEK293
IGFBP-7 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06649
Species: Human
Expression System: HEK293
IGFBP-7 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06644
Species: Human
Expression System: HEK293
IGFBP-7 Protein, Mouse, Recombinant (aa 26-281, His)
TMPY-06879
Species: Mouse
Expression System: HEK293
SMYD3 Protein, Human, Recombinant (GST)
TMPY-01268
Species: Human
Expression System: Baculovirus-Insect Cells
KRAS Protein, Human, Recombinant (G12S, GST)
TMPU-00001
Species: Human
Expression System: E. coli
CCL20 Protein, Mouse, Recombinant (His)
TMPY-02770
Species: Mouse
Expression System: Baculovirus-Insect Cells
CCL20 Protein, Mouse, Recombinant
TMPY-04889
Species: Mouse
Expression System: E. coli
KRAS Protein, Human, Recombinant (G12C, His)
TMPJ-00510
Species: Human
Expression System: E. coli
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カタログ番号 製品名
L6740 Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library

386 compounds
A collection of 386 TCM monomers with anti-colorectal activity. An effective tool for drug development and pharmacological studies.
L2194 Anti-Colorectal Cancer Compound Library

1565 compounds
1565 compounds associated with colorectal cancer that can be used for high-throughput and high-content screening.

ライブラリー

Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library
L6740
Compounds: 386
Anti-Colorectal Cancer Compound Library
L2194
Compounds: 1565
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