| TN1635 |
Euphorbia factor L8
|
|
Others
|
|
Euphorbia factor L8 is a diterpene from Morinda citrifolia seeds. |
| TN1634 |
Euphorbia factor L7b
|
|
Others
|
|
Euphorbia factor L7b,a natural product obtained from the herbs of Euphorbia pekinensis Rupr. |
| T2S0410 |
Euphorbia factor L1
|
Euphorbiasteroid |
Apoptosis
,
P-gp
|
|
Euphorbia factor L1 (Euphorbiasteroid) can reduce Bcl-2, PI3K, AKT, and mTOR protein and mRNA levels, and up-regulate caspase-9 and caspase-3 protein levels. It induces autophagy and has anti-cancer, anti-adipogenic, ant... |
| T5798 |
Euphorbia Factor L2
|
euphorbiafactor L2 |
Apoptosis
,
NF-κB
|
|
Euphorbia Factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation. |
| T3220 |
Euphorbiasteroid
|
Euphobiasteroid,Euphorbia factor L1 |
Others
,
AMPK
|
|
Euphorbiasteroid (Euphobiasteroid) (25-50 μM) decreased differentiation of 3T3-L1 cells via reduction of intracellular triglyceride (TG) accumulation. |
| TQ0099 |
20-O-Acetylingenol-3-angelate
|
Euphorbia factor Pe1 |
Others
|
|
20-O-Acetylingenol-3-angelate (Euphorbia factor Pe1) is a natural compound found in the leaves and stems of the plant Inga. It has a variety of biological activities including tumor growth inhibition, anti-inflammatory, ... |
| T125211 |
Deoxy euphorbia factor L1
|
|
Others
|
|
Deoxy euphorbia factor L1 is a natural product found in the seeds of Euphorbia lathyris L |
| T4S2014 |
5,15-Diacetyl-3-benzoyllathyrol
|
Euphorbia factor L3 |
Others
|
|
1. 5,15-Diacetyl-3-benzoyllathyrol (Euphorbia factor L3) is a melanine production inhibitor, excellent in inhibiting pigment stagnation and improving the discoloration of the skin or freckles, has excellent stability. |
| TN1633 |
Euphorbia factor L7a
|
|
Others
|
|
Euphorbia factor L7a is a diterpene found in the seeds of Morinda citrifolia. |
| TN1006 |
Tirucallol
|
|
NOS
,
NO Synthase
,
Prostaglandin Receptor
|
|
Tirucallol is an antiinflammatory agent isolated from Euphorbia lactea.Tirucallol exerts a topical anti-inflammatory effect in vivo, via a mechanism of action related to the neutrophil migration. |
| T5689 |
20-DEOXYINGENOL
|
|
Others
,
Autophagy
|
|
20-DEOXYINGENOL is a natual product. |
| T2S1040 |
Jolkinolide B
|
|
ERK
,
IL Receptor
,
BCL
,
p38 MAPK
,
TNF
,
NF-κB
,
Akt
,
Caspase
,
PI3K
,
JAK
,
JNK
,
STAT
,
mTOR
|
|
Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud. Jolkinolide B induces apoptosis in cancer cells. Jolkinolide B can be used for studies on preventing and treating osteolysis. |
| TN1765 |
Ingenol-3,4,5,20-diacetonide
|
Ingenol-3,4:5,20-diacetonide |
Others
|
|
Ingenol-3,4,5,20-diacetonide is a natural product isolated from the sap of the Euphorbia plant. It has been found to possess a wide range of biological activities including anti-tumor, anti-inflammatory and immunomodulat... |
| T5737 |
Euphol
|
|
Others
,
Lipase
,
Endogenous Metabolite
|
|
Euphol, an alcohol tetracyclic triterpene, has a wide range of pharmacological properties and is considered to have anti-inflammatory action. |
| T82430 |
Euphebracteolatin B
|
|
|
|
Euphebracteolatin B, a natural product, can be isolated from the plant Euphorbia fischeriana [1]. |
| T38805 |
Euphol acetate
|
|
|
|
Euphol acetate, a triterpene found in Euphorbia broteri, has demonstrated inhibitory effects on the hepatic transport proteins known as organic anion-transporting polypeptide 1/3 (OATP1B1/3). |
| T15258 |
Euphorbadienol
|
alpha-Euphorbol |
Others
|
|
Euphorbadienol is a triterpenic compound isolated from the latex of Euphorbia resinifera. It has antileishmanial and antitrypanosomal activity. |
| TN4059 |
Fischeria A
|
|
Others
|
|
Fischeria A is a natural product of Euphorbia, Euphorbiaceae. The catalog number is TN4059 and the CAS number is 221456-63-9. Fischeria A can be used as a reference standard. |
| TN4252 |
Ingenol 20-palmitate
|
|
Others
|
|
Ingenol 20-palmitate is a natural product from Euphorbia sieboldiana. |
| TN2390 |
1,2:4,5-Di-O-isopropylidene-β-D-fructopyranose
|
|
Others
|
|
1,2:4,5-Di-O-isopropylidene-β-D-fructopyranose is a natural from Euphorbia macroclada |
| T83532 |
(Rac)-Dehydrovomifoliol
|
PBI 344 |
|
|
(Rac)-Dehydrovomifoliol (PBI 344), a bisnorsesquiterpene, is present in Euphorbia peplus [1]. |
| T82428 |
Euphorblin R
|
EOF2 |
|
|
Euphorblin R (EOF2), a rhamnyl diterpenoid extracted from Euphorbia resinifera, has been shown to enhance lysosomal biogenesis, suggesting its utility in researching lysosome-associated diseases. |
| TN3957 |
Ent-Atisane-3beta,16alpha,17-triol
|
|
Others
|
|
ent-Atisane-3beta,16alpha,17-triol is a natural product of Euphorbia, Euphorbiaceae. The catalog number is TN3957 and the CAS number is 115783-44-3. ent-Atisane-3beta,16alpha,17-triol can be used as a reference standard. |
| T13503 |
31-Norlanostenol
|
|
Others
|
|
31-Norlanostenol is a triterpene isolated from the latex of Euphorbia officinarum. It can act as an efficient insect growth regulator on S. frugiperda and Tenebrio molitor. |
| T81989 |
Kansenone
|
|
|
|
Kansenone, a euphane-type triterpene, is extractable from Euphorbia kansui using a 60% ethanol (EtOH) solution [1]. |
| T82070 |
Ingol 7,8,12-triacetate 3-(4-methoxyphenyl)acetate
|
|
|
|
Ingol 7,8,12-triacetate 3-(4-methoxyphenyl)acetate, a complex ingol diterpene derived from the latex of Euphorbia officinarum, features multiple acetate functional groups [1]. |
| T82427 |
Euphoscopin C
|
|
|
|
Euphoscopin C, a diterpenoid isolated from Euphorbia helioscopia, significantly enhances the cytotoxic activity of natural killer (NK) cells against H1299-luci and A549-luci cells [1]. |
| TN3946 |
Ent-3-Oxokaurane-16,17-diol
|
|
Others
|
|
AKaurane-3,16,17-triol,ent-kaurane-3-oxo-16α,17-diol,and ent-16α,17-dihydroxyatisan-3-one are three kinds of toxic diterpenoids isolated from the roots of genus Euphorbia. |
| TN3959 |
Ent-kaurane-3,16,17-triol
|
|
Others
|
|
Kaurane-3,16,17-triol,ent-kaurane-3-oxo-16α,17-diol,and ent-16α,17-dihydroxyatisan- 3-one are three kinds of toxic diterpenoids isolated from the roots of genus Euphorbia. |
| TN2890 |
3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one
|
|
Trk receptor
|
|
3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one is a natural product of Euphorbia, Euphorbiaceae. The catalog number is TN2890 and the CAS number is 244277-75-6. 3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6... |
| TN4379 |
Kansuinine A
|
|
IL Receptor
,
STAT
,
Interleukin
|
|
Kansuinine A possesses analgesic props, it also shows NGF inducing activity. |
| TN5025 |
Simiarenone
|
|
Others
|
|
Simiarenone is a natural product of Euphorbia, Euphorbiaceae. The catalog number is TN5025 and the CAS number is 2318-78-7. Simiarenone can be used as a reference standard. |
| TN6528 |
Butyrospermol
|
|
Others
|
|
Butyrospermol is a protolimonoid extracted from shea (Euphorbia). As a long-chain fatty acid ester first discovered from natural products, Butyrospermol has antifeedant and antitumor activities. |
| TN1196 |
17-Hydroxyisolathyrol
|
|
Others
|
|
17-Hydroxyisolathyrol is a natural product |
| TQ0316 |
Ingenol-5,20-acetonide-3-O-angelate
|
Ingenol 5,20-acetonide 3-angelate,Ingenol 3-angelate 5,20-acetonide |
Others
|
|
Ingenol-5,20-acetonide-3-O-angelate (Ingenol 5,20-acetonide 3-angelate) is a natural product. |
| TN1047 |
Ingenol mebutate
|
Ingenol 3-Angelate,PEP005 |
gp120/CD4
,
HIV Protease
,
PKC
|
|
Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory a... |
| TN1049 |
Ingenol-5,20-acetonide
|
|
Others
|
|
Ingenol-5,20-acetonide is a natural compound, an analog of Ingenol 3-Angelate. It has antitumor activity when used topically in the treatment of actinic keratoses. |
| TQ0198 |
Phorbol 12-myristate 13-acetate
|
PMA |
NF-κB
,
S1P Receptor
,
PKC
|
|
Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB. Phorbol 12-myristate 13-acetate induces THP1 cell differentiation. |
| T3S2019 |
Lathyrol
|
|
Others
|
|
1.Lathyrol diterpenes is a modulator of P-glycoprotein dependent multidrug resistance. |
| T5679 |
(E)-Ferulic acid
|
trans-Ferulic acid,(E)-Coniferic acid |
BCL
,
Ferroptosis
,
Wnt/beta-catenin
,
Endogenous Metabolite
|
|
(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pr... |
| T5S2017 |
Ingenol
|
(-)-Ingenol |
PKC
|
|
1. Ingenol ((-)-Ingenol) mebutate is an effective treatment for actinic keratosis. 2. Formulating novel derivatives from Ingenol esters may be an innovative approach to develop new lead compounds to reactivate latent HIV... |
| TQ0164 |
Dodecanoic acid ingenol ester
|
13-Oxyingenol dodecanoat |
Others
|
|
Dodecanoic acid ingenol ester, a natural compound, shows moderate cytotoxicity with IC50 values being 35.59 μM (Caco-2), 24.04 μM (MCF-7), and 22.24 μM (MCF-7/ADM). |
| TN3932 |
Ent-11alpha-Hydroxyabieta-8(14),13(15)-dien-16,12alpha-olide
|
|
Others
|
|
ent-11alpha-Hydroxyabieta-8(14),13(15)-dien-16,12alpha-olide shows significant cytotoxic activity against ANA-1 and Jurkat cells with IC50 values 7.12 x 10(-3) and 1.79 x 10(-2) microM. |
| T3S2016 |
Epoxylathyrol
|
|
Others
|
|
Epoxylathyrol derivatives have modulation of ABCB1-mediated multidrug resistance in human colon adenocarcinoma and mouse T-Lymphoma cells. |
| TN5597 |
Gopherenediol
|
|
|
|
Gopherenediol shows weak antifeedant activity. |
| TN2603 |
12-Ursene-3,16,22-triol
|
|
Others
|
|
12-Ursene-3,16,22-triol is a natural product for research related to life sciences. The catalog number is TN2603 and the CAS number is 1242085-06-8. |
| TN3937 |
Ent-16alpha,17-Dihydroxyatisan-3-one
|
|
P-gp
|
|
ent-16alpha,17-Dihydroxyatisan-3-one and ent-16alpha,17-dihydroxykauran-3-one have apoptosis induction activities on L5178 human MDR1 gene-transfected mouse lymphoma cells. |
| TN4768 |
Phorbol 13-acetate
|
|
Others
|
|
Phorbol 13-acetate is a natural product for research related to life sciences. The catalog number is TN4768 and the CAS number is 32752-29-7. |
| TN3032 |
4-Hydroxy-11,12,13-trinor-5-eudesmen-7-one
|
|
Others
|
|
4-Hydroxy-11,12,13-trinor-5-eudesmen-7-one is a natural product for research related to life sciences. The catalog number is TN3032 and the CAS number is 133369-42-3. |
| TN3958 |
Ent-Kaurane-16beta,19,20-triol
|
|
Others
|
|
ent-Kaurane-16beta,19,20-triol is a natural product for research related to life sciences. The catalog number is TN3958 and the CAS number is 167898-32-0. |
