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カタログ番号	製品名	別名	ターゲット
T36544	Prostaglandin D1	Prostaglandin D1
	Prostaglandin D1 is a prostaglandin that has contraction and relaxation effects on isolated human arteries and can inhibit ADP-induced platelet aggregation (IC50=320 ng/ml). Prostaglandin D1 can be used in metabolic stud...
T37328	Prostaglandin H1	Prostaglandin H1
	Prostaglandin H1 is the cyclooxygenase metabolite of DGLA, a CRTh2 agonist and a precursor of a family of 1 anti-inflammatory prostaglandins. Prostaglandin H1 can be used in the study of inflammation.
T37919	Prostaglandin F1α	PGF1α,Prostaglandin F1α
	Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α have been shown to act as priming pheromones for male Atlantic salmon with...
T36238	6α-Prostaglandin I1	6α-Prostaglandin I1
	6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cyclic AMP accumulation in human thyroid slices and cells in a concentration depende...
T36239	6β-Prostaglandin I1	6β-Prostaglandin I1
	6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-PGI1 has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for aden...
T35992	Ent-Prostaglandin F2α	ent-Prostaglandin F2α
	ent-Prostaglandin F2α is the enantiomer of PGF2α and is found in urine.
T35991	Ent-Prostaglandin E2	ent-Prostaglandin E2
	Enzymatically-derived prostaglandin E2 (PGE2) is an optically pure compound whereas PGE2 derived from the free radical-catalyzed peroxidation of arachidonate is a racemic mixture. Ent-PGE2 is the opposite enantiomer of P...
T36144	11β-Prostaglandin E2	11β-PGE2,11β-Prostaglandin E2
	11β-PGE2 is the C-11 epimer of PGE2. It is a moderate inhibitor of PGE2 binding to rat hypothalamic membranes with a Ki value of 53 nM.[1] 11β-PGE2 also stimulates bone resorption in rats at concentrations of 10-8 to 10-...
T38389	Prostaglandin D2 Ethanolamide	Prostaglandin D2 Ethanolamide
	Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. The ...
T38195	Prostaglandin F2α Ethanolamide	Prostaglandin F2α Ethanolamide
	Prostaglandin F2α ethanolamide (PGF2α-EA) is produced by COX-2 metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA), found in brain, liver, and other mammalian tissues. AEA can be metabolized directl...
T36455	11β-Prostaglandin F2α	11β-Prostaglandin F2α
	11β-Prostaglandin F2α is a bioactive metabolite catalyzed by AKR1C3 that stimulates prostaglandin F receptors and induces slug expression in breast cancer. 11β-Prostaglandin F2α is also an endogenous metabolite present i...
T36158	8-iso Prostaglandin A2	8-iso Prostaglandin A2
	8-iso Prostaglandin A2 is an isoprostane produced by the nonenzymatic oxidation of arachidonic acid.
T36159	8-iso Prostaglandin E1	8-iso Prostaglandin E1
	8-iso Prostaglandin E1 causes spasm in the pulmonary veins of dogs and also acts as a vasodilator.
T27066	Prostaglandin G/H synthase 1 inhibitor	CP74006,CP 74006,2-Amino-N-(4-chlorophenyl)benzamide	Others
	Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.		Others
T36209	15-keto Prostaglandin A1	15-keto Prostaglandin A1
	Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. 15-keto PGA1 is a metabolite of PGA1, produced by 15-hydroxy PG dehydrogenase. It can be produced from PGA1 ...
T36041	16,16-dimethyl Prostaglandin A2	16,16-dimethyl Prostaglandin A2
	16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by >90% at a concentration of 4...
T36213	16,16-dimethyl Prostaglandin D2	16,16-dimethyl Prostaglandin D2
	16,16-dimethyl PGD2 is a metabolically stable synthetic analog of PGD2. It enhances ADP-induced human platelet aggregation and increases systemic blood pressure in rats.
T37840	20-hydroxy Prostaglandin F2α	20-hydroxy Prostaglandin F2α
	20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing ...
T36162	8-iso Prostaglandin F1α	8-iso Prostaglandin F1α
	8-iso PGF1α is an isoprostane that was first identified in human semen. It is a member of the isoprostane family, which are eicosanoids of non-cyclooxygenase origin. 8-iso PGF1α is present along with its 19-hydroxy conge...
T36770	11-deoxy Prostaglandin E1	11-deoxy Prostaglandin E1
	11-deoxy Prostaglandin E1 is a prostaglandin E1 analogue that has bronchodilator activity and can inhibit histamine-induced bronchoconstriction and cause relaxation of tracheal strips in isolated guinea pigs.
T36214	16,16-dimethyl Prostaglandin E1	16,16-dimethyl Prostaglandin E1
	16,16-dimethyl Prostaglandin E1 is a PGE1 (T1626) analog that induces bronchoconstriction and vascular smooth muscle contraction and inhibits indomethacin-induced cell elongation.
T36040	16,16-dimethyl Prostaglandin A1	16,16-dimethyl Prostaglandin A1
	16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences. The catalog number is T36040 and the CAS number is 41692-24-4.
T36157	8-iso Prostaglandin A1	8-iso Prostaglandin A1
	8-iso Prostaglandin A1 (8-iso PGA1) is an isoprostane and a member in a large family of prostanoids of non-cyclooxygenase origin. It occurs as a common minor impurity in most commercial preparations of PGE1. The biologic...
T36160	8-iso Prostaglandin E2	8-iso Prostaglandin E2
	8-iso PGE2 is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. It is a potent renal vasoconstrictor in the rat. 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with ...
T36546	Prostaglandin I3 (sodium salt)	Prostaglandin I3 (sodium salt)
	PGI3 is synthesized from EPA by COX and PGI synthase. PGI3 has a short in vivo half-life and is hydrolyzed to δ17-6-keto PGF1α. The platelet and vascular activity of PGI3 is equivalent to that of PGI2.
T36726	6-keto Prostaglandin E1	6-keto Prostaglandin E1
	6-keto Prostaglandin E1 is a bioactive derivative of PGE1 that plays a role in antiplatelet aggregation and depolymerization.
T38342	11-deoxy Prostaglandin E2	11-deoxy Prostaglandin E2
	11-deoxy Prostaglandin E2 (11-deoxy PGE2) is a stable, synthetic analog of PGE2 . In contrast to PGE2 which has bronchodilation effects, 11-deoxy PGE2 is a powerful bronchoconstrictor and contracts human respiratory trac...
T37839	20-hydroxy Prostaglandin E2	20-hydroxy Prostaglandin E2
	20-hydroxy Prostaglandin E2 (20-hydroxy PGE2) is a product of cytochrome P450 metabolism of PGE2 . ω-Oxidation at C-20 followed by β-oxidation and the loss of up to four carbons from the lower side chain is a prominent m...
T36775	13,14-dihydro Prostaglandin E1	13,14-dihydro Prostaglandin E1
	13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and wash...
T36772	11-deoxy Prostaglandin F1β	11-deoxy Prostaglandin F1β
	11-deoxy PGF1β is a synthetic analog of PGF1β. In contrast to PGF2α and PGF1α, 11-deoxy PGF1β exhibits vasodepressor and bronchodilator activities in guinea pigs at a dose of 500 μg/kg.
T37165	8-iso Prostaglandin F2β	8-iso Prostaglandin F2β
	8-iso Prostaglandin F2β can be used in related research in the field of life sciences. Its product number is T37165 and CAS number is 177020-26-7.
T37993	16,16-dimethyl Prostaglandin F2α	16,16-dimethyl Prostaglandin F2α
	16,16-dimethyl Prostaglandin F2α can be used in related research in the field of life sciences. Its product number is T37993 and CAS number is 39746-23-1.
T37327	Prostaglandin F2α 1,15-lactone	Prostaglandin F2α 1,15-lactone
	PGF2α 1,15-lactone is a lipid-soluble internal ester of PGF2α. Hydrolysis of the lactone readily produces free PGF2α in plasma. In rhesus monkeys, a total dose of 15 mg of PGF2α 1,15-lactone terminates early pregnancy, w...
T36163	8-iso Prostaglandin F1β	8-iso Prostaglandin F1β
	8-iso PGF1β is a potential autoxidation product of DGLA. There are no published reports on its isolation from any biological source or on its biological activity.
T36771	11-deoxy Prostaglandin F1α	11-deoxy Prostaglandin F1α
	11-deoxy PGF1α is a synthetic analog of PGF1α. In whole animal studies, a dose of 32 mg/kg inhibited gastric acid secretion by 35%. 11-deoxy PGF1α is also known to cause rat uterine contractions at a dose 0.3 times that ...
T37990	15-keto Prostaglandin F1α	15-keto Prostaglandin F1α
	15-keto PGF1α is the initial metabolite of PGF1α via 15-hydroxy PGDH. In mammals, oxidation of C-15 markedly attenuates receptor binding and activity. In fish, the 15-keto compounds serve as post-ovulatory pheromones and...
T36545	Prostaglandin D2 methyl ester	Prostaglandin D2 methyl ester
	Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. It causes vasodilation, flushing, hypoten...
T38196	Prostaglandin F2α isopropyl ester	Prostaglandin F2α isopropyl ester
	PGF2α isopropyl ester is an ester prodrug of PGF2α with enhanced lipid solubility. Due to better membrane penetration, PGF2α isopropyl ester is more suitable than PGF2α or PGF2α tromethamine salt for topical application ...
T37918	Prostaglandin E2 isopropyl ester	Prostaglandin E2 isopropyl ester
	Prostaglandin E2 (PGE2) isopropyl ester is a more lipophilic form of the free acid, PGE2. PG esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid by end...
T36219	1a,1b-dihomo Prostaglandin E1	1a,1b-dihomo Prostaglandin E1
	1a,1b-dihomo Prostaglandin E1 is a class of prostaglandin compounds.
T37778	19(R)-hydroxy Prostaglandin E1	19(R)-hydroxy Prostaglandin E1
	19(R)-hydroxy Prostaglandin E1 is an agonist of EP1 and EP3 receptor subtypes and exhibits contractile activity on smooth muscle and is the major prostaglandin in primate semen.
T37275	2,3-dinor-11β-Prostaglandin F2α	2,3-dinor-11β-Prostaglandin F2α
	2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiol...
T36146	13,14-dihydro Prostaglandin F2α	13,14-dihydro Prostaglandin F2α,13,14-dihydro PGF2α
	13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2α. The ED50 value...
T36164	8-iso Prostaglandin F3α	8-iso Prostaglandin F3α,8-epi PGF3α
	8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA. Little is known about the biological activity of 8-iso PGF3α. There is one report that it is inactive in a TP receptor mediated assay of h...
T36045	1a,1b-dihomo Prostaglandin E2	1a,1b-dihomo Prostaglandin E2
	1a,1b-dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid . 1a,1b-dihomo PGE2 has also b...
T37995	16-phenoxy tetranor Prostaglandin F2α	16-phenoxy tetranor Prostaglandin F2α
	16-phenoxy PGF2α is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.
T36617	Ent-8-iso Prostaglandin F2α	ent-8-iso Prostaglandin F2α
	ent-8-iso Prostaglandin F2α is a potent vasoconstrictor of porcine retinal and cerebral microvessels with EC50 values of 30.6 and 53.5 nM, respectively.
T37946	17-trifluoromethylphenyl trinor Prostaglandin F2α	17-trifluoromethylphenyl trinor Prostaglandin F2α
	A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most pote...
T36621	Prostaglandin F2β
	Prostaglandin F2β (PGF2β) is the 9β-hydroxy stereoisomer of PGF2α. It is much less active than PGF2α in antifertility and bronchoconstrictor activities. PGF2β exhibits bronchodilating activity in guinea pigs and cats and...
T35961	Prostaglandin Bx
	PGBx is a mixture of oligomers of PGB1 with a molecular weight of 1,000-1,500. It has antioxidant and free radical trapping activity that was first studied in isolated mitochondria.1 PGBx has anti-inflammatory and cytopr...

Compounds

Prostaglandin D1

T36544

Synonym: Prostaglandin D1

Target:

Prostaglandin H1

T37328

Synonym: Prostaglandin H1

Target:

Prostaglandin F1α

T37919

Synonym: PGF1α,Prostaglandin F1α

Target:

6α-Prostaglandin I1

T36238

Synonym: 6α-Prostaglandin I1

Target:

6β-Prostaglandin I1

T36239

Synonym: 6β-Prostaglandin I1

Target:

ent-Prostaglandin F2α

T35992

Synonym: ent-Prostaglandin F2α

Target:

ent-Prostaglandin E2

T35991

Synonym: ent-Prostaglandin E2

Target:

11β-Prostaglandin E2

T36144

Synonym: 11β-PGE2,11β-Prostaglandin E2

Target:

Prostaglandin D2 Ethanolamide

T38389

Synonym: Prostaglandin D2 Ethanolamide

Target:

Prostaglandin F2α Ethanolamide

T38195

Synonym: Prostaglandin F2α Ethanolamide

Target:

11β-Prostaglandin F2α

T36455

Synonym: 11β-Prostaglandin F2α

Target:

8-iso Prostaglandin A2

T36158

Synonym: 8-iso Prostaglandin A2

Target:

8-iso Prostaglandin E1

T36159

Synonym: 8-iso Prostaglandin E1

Target:

Prostaglandin G/H synthase 1 inhibitor

T27066

Synonym: CP74006,CP 74006,2-Amino-N-(4-chlorophenyl)benzamide

Target: Others

15-keto Prostaglandin A1

T36209

Synonym: 15-keto Prostaglandin A1

Target:

16,16-dimethyl Prostaglandin A2

T36041

Synonym: 16,16-dimethyl Prostaglandin A2

Target:

16,16-dimethyl Prostaglandin D2

T36213

Synonym: 16,16-dimethyl Prostaglandin D2

Target:

20-hydroxy Prostaglandin F2α

T37840

Synonym: 20-hydroxy Prostaglandin F2α

Target:

8-iso Prostaglandin F1α

T36162

Synonym: 8-iso Prostaglandin F1α

Target:

11-deoxy Prostaglandin E1

T36770

Synonym: 11-deoxy Prostaglandin E1

Target:

16,16-dimethyl Prostaglandin E1

T36214

Synonym: 16,16-dimethyl Prostaglandin E1

Target:

16,16-dimethyl Prostaglandin A1

T36040

Synonym: 16,16-dimethyl Prostaglandin A1

Target:

8-iso Prostaglandin A1

T36157

Synonym: 8-iso Prostaglandin A1

Target:

8-iso Prostaglandin E2

T36160

Synonym: 8-iso Prostaglandin E2

Target:

Prostaglandin I3 (sodium salt)

T36546

Synonym: Prostaglandin I3 (sodium salt)

Target:

6-keto Prostaglandin E1

T36726

Synonym: 6-keto Prostaglandin E1

Target:

11-deoxy Prostaglandin E2

T38342

Synonym: 11-deoxy Prostaglandin E2

Target:

20-hydroxy Prostaglandin E2

T37839

Synonym: 20-hydroxy Prostaglandin E2

Target:

13,14-dihydro Prostaglandin E1

T36775

Synonym: 13,14-dihydro Prostaglandin E1

Target:

11-deoxy Prostaglandin F1β

T36772

Synonym: 11-deoxy Prostaglandin F1β

Target:

8-iso Prostaglandin F2β

T37165

Synonym: 8-iso Prostaglandin F2β

Target:

16,16-dimethyl Prostaglandin F2α

T37993

Synonym: 16,16-dimethyl Prostaglandin F2α

Target:

Prostaglandin F2α 1,15-lactone

T37327

Synonym: Prostaglandin F2α 1,15-lactone

Target:

8-iso Prostaglandin F1β

T36163

Synonym: 8-iso Prostaglandin F1β

Target:

11-deoxy Prostaglandin F1α

T36771

Synonym: 11-deoxy Prostaglandin F1α

Target:

15-keto Prostaglandin F1α

T37990

Synonym: 15-keto Prostaglandin F1α

Target:

Prostaglandin D2 methyl ester

T36545

Synonym: Prostaglandin D2 methyl ester

Target:

Prostaglandin F2α isopropyl ester

T38196

Synonym: Prostaglandin F2α isopropyl ester

Target:

Prostaglandin E2 isopropyl ester

T37918

Synonym: Prostaglandin E2 isopropyl ester

Target:

1a,1b-dihomo Prostaglandin E1

T36219

Synonym: 1a,1b-dihomo Prostaglandin E1

Target:

19(R)-hydroxy Prostaglandin E1

T37778

Synonym: 19(R)-hydroxy Prostaglandin E1

Target:

2,3-dinor-11β-Prostaglandin F2α

T37275

Synonym: 2,3-dinor-11β-Prostaglandin F2α

Target:

13,14-dihydro Prostaglandin F2α

T36146

Synonym: 13,14-dihydro Prostaglandin F2α,13,14-dihydro PGF2α

Target:

8-iso Prostaglandin F3α

T36164

Synonym: 8-iso Prostaglandin F3α,8-epi PGF3α

Target:

1a,1b-dihomo Prostaglandin E2

T36045

Synonym: 1a,1b-dihomo Prostaglandin E2

Target:

16-phenoxy tetranor Prostaglandin F2α

T37995

Synonym: 16-phenoxy tetranor Prostaglandin F2α

Target:

ent-8-iso Prostaglandin F2α

T36617

Synonym: ent-8-iso Prostaglandin F2α

Target:

17-trifluoromethylphenyl trinor Prostaglandin F2α

T37946

Synonym: 17-trifluoromethylphenyl trinor Prostaglandin F2α

カタログ番号	製品名	別名	ターゲット
T5014	Prostaglandin E2	PGE2,Dinoprostone,Prostaglandin E2 (PGE2)	Endogenous Metabolite , Prostaglandin Receptor
	Prostaglandin E2 (PGE2) is a naturally occurring hormone involved in a variety of physiological processes in the body, including smooth muscle contraction and relaxation, regulation of vasodilatation and constriction, re...		Endogenous Metabolite , Prostaglandin Receptor
T1626	Prostaglandin E1	PGE1,Alprostadil	Endogenous Metabolite , Prostaglandin Receptor
	Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in...		Endogenous Metabolite , Prostaglandin Receptor
T15133	Dinoprost	Prostaglandin F2a,PGF2α	Endogenous Metabolite
	Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.		Endogenous Metabolite
T13831	Prostaglandin D2	PGD2	Endogenous Metabolite
	Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals,and is a potent endogenous sleep promoting substances.		Endogenous Metabolite
T20939	Bimatoprost acid	17-phenyl trinor PGF2α,17-phenyl trinor Prostaglandin F2α	GPR
	Bimatoprost acid (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and has a potential antagonistic activity for the FP receptor. It has a relative potency of 756% compared to PGF2α for binding to the FP...		GPR
T37164	8-Isoprostaglandin F2α	8-iso Prostaglandin F2α
	8-Isoprostaglandin F2α is a natural product for research related to life sciences. The catalog number is T37164 and the CAS number is 27415-26-5.
T22473	15-deoxy-Δ-12,14-Prostaglandin J2		Others
	15-deoxy-Δ-12,14-Prostaglandin J2 is a PPARγ agonist.		Others
T2S0765	Epibetulinic acid		NO Synthase , Prostaglandin Receptor
	Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin.		NO Synthase , Prostaglandin Receptor
T14865	Carboprost tromethamine		Prostaglandin Receptor
	Carboprost tromethamine, a synthetic 15-methyl analogue of prostaglandin F2α, effectively promotes uterine contractions and significantly reduces bleeding during and post-delivery.		Prostaglandin Receptor
T3868	Agnuside	chasteberry oil	COX , Prostaglandin Receptor , P-gp
	Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, and 82.1% of P-glycoprotein (P-gp) ATPase activity at conce...		COX , Prostaglandin Receptor , P-gp
T2791	Pectolinarin		Apoptosis , Others , NO Synthase , Prostaglandin Receptor , Interleukin
	Pectolinarin is a Cirsium isolate with anti-inflammatory activity.
T4S0227	Sinensetin	Pedalitin permethyl ether	TNF , PGE Synthase
	Sinensetin (Pedalitin permethyl ether) is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin enhances adipogenesis and lipolysis.		TNF , PGE Synthase
T5727	CAFESTOL		ERK , NF-κB , COX , PGE Synthase
	CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production...		ERK , NF-κB , COX , PGE Synthase
T2S2335	Dehydroevodiamine	DHED	Others , NF-κB , COX , PGE Synthase , NO Synthase
	Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood fl...		Others , NF-κB , COX , PGE Synthase , NO Synthase
T3S2007	MRE-269	MRE 269,ACT-333679,MRE269	Prostaglandin Receptor
	MRE-269 (ACT-333679) is an orally available and long-acting prostacyclin receptor agonist prodrug. MRE-269(ACT-333679) is used for the treatment of pulmonary arterial hypertension. MRE-269(ACT-333679) is an active metabo...		Prostaglandin Receptor
T5681	ETHYL CAFFEATE	ETHYL 3,4-DIHYDROXYCINNAMATE	NF-κB , COX , PGE Synthase , NO Synthase
	Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro. Furthermore, Ethyl Caffeate intensely blocked the transcriptional expression in interferon-γ-related s...		NF-κB , COX , PGE Synthase , NO Synthase
T3915	Ginsenoside Ro	Chikusetsusaponin 5,Polysciasaponin P3,Chikusetsusaponin V	Calcium Channel , Reductase , Prostaglandin Receptor
	Ginsenoside Ro (Chikusetsusaponin V) can reduce TXA2 production, weakly reduce COX-1 and TXAS activities, and has antiplatelet effects as a Ca2+ antagonist with an IC50 of 155 μM.		Calcium Channel , Reductase , Prostaglandin Receptor
T7053	P-Hydroxycinnamic acid	p-Coumaric acid,p-Cumaric acid,p-Hydroxy-cinnamic acid,NSC 59260	Thrombin , Endogenous Metabolite , Prostaglandin Receptor
	p-Hydroxycinnamic acid (NSC-59260) can inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.		Thrombin , Endogenous Metabolite , Prostaglandin Receptor
TQ0203	Tafluprost	MK2452,AFP-168	Prostaglandin Receptor
	Tafluprost, a prostaglandin analog, is the selective agonist of fluoroprostaglandin (FP) receptor PGF2α.		Prostaglandin Receptor
TMA0536	2-Acetylbenzoic acid		Prostaglandin Receptor
	2-Acetylbenzoic acid is more potent than 2-propionyloxybenzoic acid in inhibiting platelet function and platelet prostaglandin (PG) synthesis although the potencies of these agents were comparable in inhibiting prostacyc...		Prostaglandin Receptor
T4797	DEHP	Bis(2-ethylhexyl) phthalate	Others , Endogenous Metabolite
	DEHP (Bis(2-ethylhexyl) phthalate) is used to impart softness and flexibility to PVC products. DEHP has been implicated in obesity and insulin resistance. DEHP inhibits prostaglandin synthesis and adversely affects the e...		Others , Endogenous Metabolite
T3912	Saikosaponin B1		Others
	Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro.		Others
T4P2931	Linoleic acid	9,12-octadecadienoic acid,acidelinoleique,9,12-Linoleic acid	Others , Endogenous Metabolite
	Linoleic acid (9,12-octadecadienoic acid) is an essential fatty acid. Prostaglandin precursor.		Others , Endogenous Metabolite
T3903	Angoroside C		Prostaglandin Receptor
	Angoroside C is a Potential anti-inflammatory compound. Inhibitor of prostaglandin E2 release in mouse peritoneal macrophages in vitro. Shows potent antioxidative activity in reducing the oxidized OH adducts of dAMP and ...		Prostaglandin Receptor
T3411	Curdione	(+)-Curdione	P450
	Curdione ((+)-Curdione) inhibits CYP3A4 activity and the production of prostaglandin E2. Curdione inhibits proliferation of MCF-7 cells by inducing apoptosis. Curdione may be a candidate for anti-inflammatory and Y chemo...		P450
T1468	Lornoxicam	Ro 13-9297,Chlortenoxicam,TS110	COX , Endogenous Metabolite
	Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, and antipyretic properties. Lornoxicam differs from other oxicam co...		COX , Endogenous Metabolite
TN3669	Cis-N-Feruloyltyramine		Prostaglandin Receptor
	Cis-N-Feruloyltyramine is a naturally occurring compound found in various plants that shows cytotoxicity against the P-388 cancer cell line. Cis-N-Feruloyltyramine is an inhibitor of in vitro prostaglandin (PG) synthesi...		Prostaglandin Receptor
T6389	Anacardic Acid	6-pentadecylsalicylic Acid,Hydroginkgolic acid	Others , Epigenetic Reader Domain , Histone Acetyltransferase , Antibacterial
	Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial activity, antibacterial activity, and inhibits prostagland...
T4740	Elaidic acid	trans-Oleic Acid	Endogenous Metabolite
	Elaidic acid (trans-Oleic Acid) is the 9-trans isomer of oleic acid. It is a monounsaturated trans-fatty acid which can be found in partially hydrogenated cooking oils. In human platelets incubated with arachidonic acid,...		Endogenous Metabolite
TN2091	Polygalacin D		Apoptosis , IAP
	Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS and COX-2 protein and mRNA without an appreciable cytotoxi...		Apoptosis , IAP
T3P2904	α-Linolenic acid	Alpha-Linolenic Acid,Linolenic acid	Akt , PI3K
	α-Linolenic acid (Alpha-Linolenic Acid) is an essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been reported to inhibit the synthesis of prostagland...		Akt , PI3K
T3889	Platycodin D		Prostaglandin Receptor , AMPK
	Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 μM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 1...		Prostaglandin Receptor , AMPK
T10619	Bromelain		Apoptosis , Others
	Bromelain is an anti-inflammatory drug derived from pineapple stem. It acts through down-regulation of plasma kininogen, degradation of advanced glycation end-product receptors, inhibition of Prostaglandin E2 expression,...		Apoptosis , Others
T3926	Echinatin	Retrochalcone	Free radical scavengers
	Echinatin (Retrochalcone) disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liv...		Free radical scavengers
T2966	Beta-Sitosterol	Cupreol,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,22,23-Dihydrostigmasterol,Betaprost	Apoptosis , Lipase , Endogenous Metabolite
	Beta-Sitosterol (SKF 14463) has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. Beta-Sitosterol (SKF 14463) , a main dietary phytosterol foun...		Apoptosis , Lipase , Endogenous Metabolite
T6S1027	Tussilagone		Others
	1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent for the prevention and treatment of human co...		Others
T75620	(+)-Oxypeucedanin methanolate
	(+)-Oxypeucedanin methanolate (compound 9) is a natural compound that inhibits prostaglandin E2 production [1].
TQ0262	Dihomo-γ-linolenic acid	Diroleuton,all-cis-8,11,14-Eicosatrienoic acid,Ro 12-1989	Others
	Ro 12-1989 can be converted into prostaglandin E1 (PGE1). Ro 12-1989 competes with arachidonic acid for COX and lipoxygenase, inhibiting the production of arachidonic acid's eicosanoids.		Others
TN1871	Ligustroside		EGFR , Lipoxygenase , COX
	Ligustroside shows little antioxidant, and anti-inflammatory properties, it shows a significant inhibition effect on prostaglandin E2 (PGE2)-release. Ligustroside shows moderate antiviral activities against parainfluenza...		EGFR , Lipoxygenase , COX
T73066	Thielavin B
	Thielavin B, produced by Thielavia terricola, functions as an inhibitor of prostaglandin biosynthesis, specifically targeting the synthesis of prostaglandin E2 from the endoperoxide. It demonstrates significant efficacy ...
T3P2855	Chamigrenal		EGFR , NOS , PAFR , COX , Prostaglandin Receptor
	β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 macrophages. Chamigrenal shows platelet-activating factor an...		EGFR , NOS , PAFR , COX , Prostaglandin Receptor
TN6667	Spinacetin
	Spinacetin has anti-inflammatory effects, it weakly inhibited nitric oxide production and reduced prostaglandin E2 levels to different extents. It shows the activities in preventing inflammatory processes, which might be...
TN4959	Schizandriside		Prostaglandin Receptor
	Schizandriside may have anti-inflammatory effects, it has inhibitory activities against nitric oxide and prostaglandin E(2) production in IFN-γ- and lipopolysaccharide-stimulated RAW 264.7 cells. It shows significant cyt...		Prostaglandin Receptor
T37774	Thielavin A
	Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B . Thielavin A inhibits COX, blocking both the conversion of arachidonic acid to prostaglandin H2 and the conversion ...
TN1378	α-Viniferin	ALPHA-VINIFERIN	P450 , NO Synthase , Prostaglandin Receptor
	α-Viniferin known as 2-arylbenzofuran flavonoids, that are inhibitors of prostaglandin H2 synthetase. α-Viniferin has anti-Alzheimer's disease, anti-tuberculosis, anti-tumor, anti-inflammation, anti-diabetes and other ph...		P450 , NO Synthase , Prostaglandin Receptor

天然物製品

Prostaglandin E2

T5014

Synonym: PGE2,Dinoprostone,Prostaglandin E2 (PGE2)

Target: Endogenous Metabolite, Prostaglandin Receptor

Prostaglandin E1

T1626

Synonym: PGE1,Alprostadil

Target: Endogenous Metabolite, Prostaglandin Receptor

Dinoprost

T15133

Synonym: Prostaglandin F2a,PGF2α

Target: Endogenous Metabolite

Prostaglandin D2

T13831

Synonym: PGD2

Target: Endogenous Metabolite

Bimatoprost acid

T20939

Synonym: 17-phenyl trinor PGF2α,17-phenyl trinor Prostaglandin F2α

Target: GPR

8-Isoprostaglandin F2α

T37164

Synonym: 8-iso Prostaglandin F2α

Target:

15-deoxy-Δ-12,14-Prostaglandin J2

Target: NO Synthase, Prostaglandin Receptor

Carboprost tromethamine

T14865

Synonym:

Target: Prostaglandin Receptor

Agnuside

T3868

Synonym: chasteberry oil

Target: COX, Prostaglandin Receptor, P-gp

Pectolinarin

T2791

Synonym:

Target: Apoptosis, Others, NO Synthase, Prostaglandin Receptor, Interleukin

Sinensetin

T4S0227

Synonym: Pedalitin permethyl ether

Target: TNF, PGE Synthase

CAFESTOL

T5727

Synonym:

Target: ERK, NF-κB, COX, PGE Synthase

Dehydroevodiamine

T2S2335

Synonym: DHED

Target: Others, NF-κB, COX, PGE Synthase, NO Synthase

MRE-269

T3S2007

Synonym: MRE 269,ACT-333679,MRE269

Target: Prostaglandin Receptor

ETHYL CAFFEATE

T5681

Synonym: ETHYL 3,4-DIHYDROXYCINNAMATE

Target: NF-κB, COX, PGE Synthase, NO Synthase

Ginsenoside Ro

T3915

Synonym: Chikusetsusaponin 5,Polysciasaponin P3,Chikusetsusaponin V

Target: Calcium Channel, Reductase, Prostaglandin Receptor

p-Hydroxycinnamic acid

T7053

Synonym: p-Coumaric acid,p-Cumaric acid,p-Hydroxy-cinnamic acid,NSC 59260

Target: Thrombin, Endogenous Metabolite, Prostaglandin Receptor

Tafluprost

TQ0203

Synonym: MK2452,AFP-168

Target: Prostaglandin Receptor

2-Acetylbenzoic acid

TMA0536

Synonym:

Target: Prostaglandin Receptor

DEHP

T4797

Synonym: Bis(2-ethylhexyl) phthalate

Target: Others, Endogenous Metabolite

Synonym: 9,12-octadecadienoic acid,acidelinoleique,9,12-Linoleic acid

Target: Others, Endogenous Metabolite

Angoroside C

T3903

Synonym:

Target: Prostaglandin Receptor

Curdione

T3411

Synonym: (+)-Curdione

Target: P450

Lornoxicam

T1468

Synonym: Ro 13-9297,Chlortenoxicam,TS110

Target: COX, Endogenous Metabolite

Cis-N-Feruloyltyramine

TN3669

Synonym:

Target: Prostaglandin Receptor

Anacardic Acid

T6389

Synonym: 6-pentadecylsalicylic Acid,Hydroginkgolic acid

Target: Others, Epigenetic Reader Domain, Histone Acetyltransferase, Antibacterial

Elaidic acid

T4740

Synonym: trans-Oleic Acid

Target: Endogenous Metabolite

Polygalacin D

TN2091

Synonym:

Target: Apoptosis, IAP

α-Linolenic acid

T3P2904

Synonym: Alpha-Linolenic Acid,Linolenic acid

Target: Prostaglandin Receptor, AMPK

Bromelain

T10619

Synonym:

Target: Apoptosis, Others

Echinatin

T3926

Synonym: Retrochalcone

Target: Free radical scavengers

Beta-Sitosterol

T2966

Synonym: Cupreol,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,22,23-Dihydrostigmasterol,Betaprost

Target: Apoptosis, Lipase, Endogenous Metabolite

(+)-Oxypeucedanin methanolate

T75620

Synonym:

Target:

Dihomo-γ-linolenic acid

TQ0262

Synonym: Diroleuton,all-cis-8,11,14-Eicosatrienoic acid,Ro 12-1989

Target: EGFR, Lipoxygenase, COX

Target: EGFR, NOS, PAFR, COX, Prostaglandin Receptor

Target: Prostaglandin Receptor

Synonym: ALPHA-VINIFERIN

Target: P450, NO Synthase, Prostaglandin Receptor

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-03120	Prostaglandin D2 Synthase Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Prostaglandin D2 Synthase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.1 kDa and the accession number is P41222.
TMPY-05069	Prostaglandin D2 Synthase Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	Prostaglandin D2 Synthase Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.3 kDa and the accession number is A6JT70.
TMPY-04624	Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.9 kDa and the accession number is O09114-1.
TMPY-01736	COX-2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a perox...
TMPY-03876	PTGFRN Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	EWI-F, also known as PTGFRN, is inversely related to the loss of CD9. Its expression correlates with the metastatic status of hLT. EWI-F inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP rece...
TMPJ-00690	PGDS Protein, Human, Recombinant	Human	E. coli
	Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macroph...
TMPY-04077	HPGDS/PGD2 Protein, Human, Recombinant (His)	Human	E. coli
	HPGDS/PGD2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.2 kDa and the accession number is O60760.
TMPH-01039	CBR1 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	CBR1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.2?kDa and the accession number is P16152.
TMPH-01040	CBR1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	CBR1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 32.2 kDa and the accession number is P16152.
TMPJ-00348	CD316 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Immunoglobulin Superfamily Member 8 (IGSF8) is a single-pass membrane protein. IGSF8 contains four Ig-like C2 type domains. The Ig-like C2-type domains 3 and 4 are required for interactions with CD81. IGSF8 may regulate ...
TMPH-02683	GSTP1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). ...
TMPH-01399	GSTP1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). ...
TMPH-01398	GSTP1 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). ...
TMPH-02438	IL-1 alpha/IL1A Protein, Rhesus macaque, Recombinant (His & SUMO)	Rhesus	E. coli
	Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammat...
TMPJ-01010	PLA2G16 Protein, Human, Recombinant (His)	Human	E. coli
	Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differenti...
TMPJ-00962	AKR1C3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate...
TMPJ-01392	IL-1 beta/IL-1F2 Protein, Cavia porcellus, Recombinant (His)	Cavia porcellus	E. coli
	Interleukin-1 beta (IL1B) belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and per...
TMPY-02945	Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	EG-VEGF, also known as prokineticin-1, is a member of the AVIT (prokineticin) family. Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. EG-VEG...
TMPH-02690	PLA2G10 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatid...

Prostaglandin D2 Synthase Protein, Human, Recombinant (His)

TMPY-03120

Species: Human

Expression System: HEK293 Cells

Prostaglandin D2 Synthase Protein, Rat, Recombinant (His)

TMPY-05069

Species: Rat

Expression System: HEK293 Cells

Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His)

TMPY-04624

Species: Mouse

Expression System: HEK293 Cells

COX-2 Protein, Human, Recombinant (His)

TMPY-01736

Species: Human

Expression System: Baculovirus Insect Cells

PTGFRN Protein, Cynomolgus, Recombinant (His)

TMPY-03876

Species: Cynomolgus

Expression System: HEK293 Cells

PGDS Protein, Human, Recombinant

TMPJ-00690

Species: Human

Expression System: E. coli

HPGDS/PGD2 Protein, Human, Recombinant (His)

TMPY-04077

Species: Human

Expression System: E. coli

CBR1 Protein, Human, Recombinant (E. coli, His)

TMPH-01039

Species: Human

Expression System: E. coli

CBR1 Protein, Human, Recombinant (His)

TMPH-01040

Species: Human

Expression System: P. pastoris (Yeast)

CD316 Protein, Human, Recombinant (hFc)

TMPJ-00348

Species: Human

Expression System: HEK293 Cells

GSTP1 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02683

Species: Mouse

Expression System: E. coli

GSTP1 Protein, Human, Recombinant (His)

TMPH-01399

Species: Human

Expression System: P. pastoris (Yeast)

GSTP1 Protein, Human, Recombinant (E. coli, His)

TMPH-01398

Species: Human

Expression System: E. coli

IL-1 alpha/IL1A Protein, Rhesus macaque, Recombinant (His & SUMO)

TMPH-02438

Species: Rhesus

Expression System: E. coli

PLA2G16 Protein, Human, Recombinant (His)

TMPJ-01010

Species: Human

Expression System: E. coli

AKR1C3 Protein, Human, Recombinant (His)

TMPJ-00962

Species: Human

Expression System: HEK293 Cells

IL-1 beta/IL-1F2 Protein, Cavia porcellus, Recombinant (His)

TMPJ-01392

Species: Cavia porcellus

Expression System: E. coli

Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His)

TMPY-02945

Species: Human

Expression System: Baculovirus Insect Cells

PLA2G10 Protein, Mouse, Recombinant (His & Myc)

TMPH-02690

Species: Mouse

Expression System: E. coli

カタログ番号	製品名
L4710	Nonsteroidal Anti-Inflammatory Compound Library		530 compounds
	530 non-steroidal anti-inflammatory compounds for high-throughput and high-content screening.

ライブラリー

Nonsteroidal Anti-Inflammatory Compound Library

L4710

Compounds: 530