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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T80528 | Ssm spooky toxin | SsTx Toxin | Potassium Channel |
Ssm Spooky Toxin, derived from Scolopendra mutilans, exhibits potent lethality affecting both hematological and respiratory systems primarily through the inhibition of KCNQ (voltage-gated potassium channel family 7) chan... | |||
T82700 | Cn2 toxin | β-Mammal toxin Cn2 | |
Cn2 toxin, a β-toxin, interacts with the voltage-sensing domain of voltage-gated sodium channels (NaV) [1]. | |||
T35775 | HT-2 Toxin-13C22 | HT-2 Toxin-13C22 | |
HT-2 toxin-13C22is intended for use as an internal standard for the quantification of HT-2 toxin by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene... | |||
TP1588 | Tetanus toxin (830-843) | Tetanus toxin 830-843 | |
Tetanus toxin (830-843) from tetanus toxoid is a universal human tetanus toxin T cell epitope. It induces T-cell activation and is used as a helper peptide in vaccinations. | |||
T35774 | HC Toxin | ||
HC Toxin is a cell-permeable, reversible inhibitor of histone deacetylases (HDACs) (IC50 = 30 nM). Through its effects on HDACs, HC toxin has been shown to up-regulate the expression of 15-lipoxygenase-1 in colorectal ca... | |||
TP1588L | Tetanus toxin 830-843 acetate | Tetanus toxin 830-843 acetate(119260-99-0 free base) | Others |
Tetanus toxin 830-843 acetate (Tetanus toxin 830-843 acetate (119260-99-0 free base)) from tetanus toxoid is a universal human tetanus toxin T cell epitope. It induces T-cell activation and is used as a helper peptide in... | |||
T34906 | Toxin IIc | ||
Toxin IIc is a biochemical. | |||
T9541 | CTB | Cholera Toxin B subunit | Epigenetic Reader Domain |
CTB (Cholera Toxin B subunit) is an activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells. | |||
T29926 | AM Toxin II | ||
AM Toxin II is a Cyclic tetradepsipeptide isolated from Alternaria mali. | |||
T29927 | AM Toxin III | ||
AM Toxin III is a phytotoxic peptide. | |||
T29804 | AK-Toxin II | ||
AK-Toxin II is a host-specific toxin to Japanese white pear. | |||
T80066 | ShK toxin | Potassium Channel | |
ShK toxin, isolated from the Caribbean sea anemone (Stichodactyla helianthus), is an inhibitor of the voltage-dependent potassium channel (Kv1.3 channel). It competes with dendrotoxin I and α-dendrotoxin in binding to ra... | |||
T80484 | Aa1 toxin | Potassium Channel | |
Aa1 toxin, sourced from Androctonus australis Garzoni venom, is a neurotoxic peptide that specifically blocks potassium channels and has applications in neurological disease research [1]. | |||
T80524 | Vm24-toxin | Vaejovis mexicanus peptide 24 | Potassium Channel |
Vm24-toxin, a peptide toxin isolated from the Mexican scorpion Vaejovis mexicanus smithi, serves as an inhibitor of the Kv1.3 potassium channel [1]. | |||
T80489 | MmTx1 toxin | Micrurotoxin 1 | GABA Receptor |
Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1]. | |||
T80487 | MmTx2 toxin | Micrurotoxin 2 | GABA Receptor |
MmTx2 toxin, extracted from the venom of the coral snake, serves as a modulator of the GABA A receptor, increasing its responsiveness to agonists. This property renders it a useful tool in researching neurological disord... | |||
T125787 | AAL Toxin TB2 | ||
AAL Toxin TB2 is a useful organic compound for research related to life sciences and the catalog number is T125787. | |||
T125562 | AAL Toxin TE2 | ||
AAL Toxin TE2 is a useful organic compound for research related to life sciences and the catalog number is T125562. | |||
T124207 | AAL Toxin TA1 | ||
AAL Toxin TA1 is a useful organic compound for research related to life sciences and the catalog number is T124207. | |||
T125567 | AAL Toxin TC1 | ||
AAL Toxin TC1 is a useful organic compound for research related to life sciences and the catalog number is T125567. | |||
T125566 | AAL Toxin TC2 | ||
AAL Toxin TC2 is a useful organic compound for research related to life sciences and the catalog number is T125566. | |||
T125565 | AAL Toxin TD1 | ||
AAL Toxin TD1 is a useful organic compound for research related to life sciences and the catalog number is T125565. | |||
T125788 | AAL Toxin TB1 | ||
AAL Toxin TB1 is a useful organic compound for research related to life sciences and the catalog number is T125788. | |||
T124258 | NT 2 Toxin | ||
NT 2 Toxin is a useful organic compound for research related to life sciences. The catalog number is T124258 and the CAS number is 76348-84-0. | |||
T80183 | Muscarinic toxin 7 | ||
Muscarinic toxin 7 (MT7) is a peptide exhibiting selective, noncompetitive antagonistic activity at the muscarinic M1 receptor [1]. | |||
T124208 | AAL Toxin TA2 | ||
AAL Toxin TA2 is a useful organic compound for research related to life sciences and the catalog number is T124208. | |||
T125563 | AAL Toxin TE1 | ||
AAL Toxin TE1 is a useful organic compound for research related to life sciences and the catalog number is T125563. | |||
T125564 | AAL Toxin TD2 | ||
AAL Toxin TD2 is a useful organic compound for research related to life sciences and the catalog number is T125564. | |||
T80168 | Scorpion toxin Tf2 | Sodium Channel | |
Scorpion toxin Tf2, a β-scorpion toxin first identified in the venom of the Brazilian scorpion Tityus fasciolatus, acts as an activator of the neuronal voltage-gated sodium (Nav) subtype Nav1.3, associated with epilepsy ... | |||
T80843 | Wasabi Receptor Toxin | WaTx | |
Wasabi Receptor Toxin (WaTx) activates TRPA1 through prolonged channel openings while reducing Ca2+ permeability. This compound has potential applications in studying both acute and persistent pain [1]. | |||
T80477 | Muscarinic toxin 3 | MT3 | Adrenergic Receptor |
Muscarinic toxin 3 (MT3), a potent non-competitive antagonist of mAChR and adrenoceptors, exhibits pIC50 values of 6.71 for M1, 8.79 for M4, 8.86 for α1A, 7.57 for α1B, 8.13 for α1D, 8.49 for α2A, <6.5 for α2B, and 7.29 ... | |||
T81011 | Tetanus Toxin (830–844) | ||
Tetanus Toxin (830–844), a biologically active peptide and a tetanus toxin-derived peptide TT830–844 CD4+ T-cell epitope, exhibits promiscuity by binding to a wide spectrum of HLA–DRB molecules. Consequently, it is antic... | |||
T73804 | Botulinum toxin type B | ||
Botulinum toxin type B, an antigen-specific exotoxin produced by the anaerobic bacterium Clostridium botulinum, is utilized in the study of neck dystonia. It inhibits the release of Acetylcholine from the neuromuscular j... | |||
T80431 | δ-Theraphotoxin-Hm1a toxin | Sodium Channel | |
δ-Theraphotoxin-Hm1a is a selective NaV1.1 activator that induces pain and touch sensitivity, with potential applications in irritable bowel syndrome research [1]. | |||
T23759 | Aspergillomarasmine A | Toxin C (Pyrenophora teres) | |
Aspergillomarasmine A is a polyamine acid naturally produced by the mold Aspergillus Versicolor. | |||
TP1063 | Psalmotoxin 1 | PcTx1,Psalmopoeus cambridgei toxin-1 | |
Psalmotoxin 1 is a potent and selective acid-sensing ion channel 1a (ASIC1a) blocker. | |||
T80530 | Spinoxin | SPX,α-KTx6.13,Potassium channel toxin alpha-KTx 6.13 | Potassium Channel |
Spinoxin, a 34-residue peptide neurotoxin extracted from the venom of Heterometrus spinifer, is characterized by four disulfide bridges. It acts as a potent inhibitor of the Kv1.3 potassium channel with an IC 50 value of... | |||
T80964 | Toxic Shock Syndrome Toxin-1 (TSST-1) (58-78) | ||
Toxic Shock Syndrome Toxin-1 (TSST-1) (58-78) acts as a T cell proliferation activator by promoting the in vitro proliferation of human peripheral blood mononuclear cells (PBMC) in a dose-dependent manner and is utilized... | |||
T80851 | VSTx-3 | Kappa-TRTX-Gr4a,κ-Theraphotoxin-Gr4a,Voltage sensor toxin 3,Peptide F | |
VSTx-3 is a potassium voltage-gated channel (K_V) blocker, which has also been shown to be a potent tetrodotoxin-sensitive (TTX-sensitive) sodium channel inhibitor, with particular efficacy against NaV1.8 channels, as ev... | |||
T16557 | PNU-159682 | Topoisomerase | |
PNU-159682 is a highly effective metabolite of the anthracycline nemorubicin. PNU-159682 has outstanding cytotoxicity. PNU-159682 is an effective ADCs cytotoxin. | |||
TP2325L | Endotoxin Inhibitor acetate(147396-10-9 free base) | Others | |
Endotoxin Inhibitor acetate has a strong blocking effect on bacterial physiological activity, thus producing antibacterial toxin Inhibitor sequences with disulfide bonds and a large amount of lysine. Endotoxin Inhibitor ... | |||
T35325L | α-Conotoxin GI acetate | α-Conotoxin GI acetate (76862-65-2 Free base) | Others |
α-Conotoxin GI acetate is a competitive antagonist of the muscle-type nicotinic acetylcholine receptors (nAChR). | |||
TP1745L | Ceratotoxin A acetate | Ceratotoxin A acetate(150671-04-8 Free base) | Antibacterial |
Ceratotoxin A acetate is isolated from the accessory gland secretion fluid, with anti-bacterial effects. | |||
TP2063L | α-Conotoxin MII acetate | α-Conotoxin MII acetate (175735-93-0 Free base) | AChR |
α-Conotoxin MII acetate is a 16-amino acid peptide from the venom of the marine snail Conus magus. α-Conotoxin MII acetate potently blocks nicotinic acetylcholine receptors composed of α3β2 subunits, with an IC50 of 0.5 ... | |||
T124797 | Ochratoxin B | Endogenous Metabolite | |
Ochratoxin B is produced by a variety of Aspergillus and Penicillium species and is an analog of the mycotoxin Ochratoxin A, which can contaminate agricultural products. | |||
T16524 | Philanthotoxin 74 dihydrochloride | PhTx-74 HCl,PhTx 74 dihydrochloride | GluR , iGluR |
Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1. | |||
T78108 | µ-Conotoxin-CnIIIC acetate | Sodium Channel | |
µ-Conotoxin-CnIIIC acetate is a potent NaV1.4 sodium channel antagonist, a conotoxin peptide consisting of 22 amino acids, used for muscle relaxation and pain relief. | |||
TP2063 | α-Conotoxin MII | AChR | |
α-Conotoxin MII is a highly potent and selective competitive antagonist for α3β2 subunit-containing nicotinic receptors (IC50 = 0.5 - 3.5 nM at α3β2 expressed in Xenopus oocytes). Also potently blocks β3-containing neuro... | |||
T21769L | β-Pompilidotoxin Acetate | β-Pompilidotoxin Acetate(216064-36-7 Free base) | Sodium Channel |
β-Pompilidotoxin Acetate is a wasp venom peptide. β-Pompilidotoxin Acetate can slow sodium channel inactivation and increase steady-state sodium current in cells. | |||
TP1289 | Cardiotoxin Analog (CTX) IV (6-12) TFA | Cardiotoxin Analog (CTX) IV (6-12) (TFA)(115722-23-1,FREE) | Others |
Cardiotoxin Analog IV (6-12) TFA, a partial peptide of Cardiotoxin Analog IV, is derived from the venom of the Taiwan Cobra, showcasing the unique properties of snake venom cardiotoxin[1]. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5625 | Zearalenone | Mycotoxin F2,RAL,F2 toxin,Toxin F2 | Others |
Zearalenone (F2 toxin) is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in cattle, pigs and sheep, with low acute toxicity. Causes precocious develo... | |||
T13726 | HT-2 Toxin | Others | |
HT-2 Toxin, a deacetylated metabolite of T-2 toxin, impairs protein synthesis and hinders cell proliferation in plants. | |||
T13053 | T-2 Toxin | T-2 Mycotoxin | Others |
T- 2 Toxin is a toxic trichothecene mycotoxin produced by various Fusarium species in feedstuffs and cereal grains,( LD50 are 5.2 and 1.5 mg/kg BWa in mice and rats,respectively ). | |||
T3381 | Lysionotin | Others | |
Lysionotin (Nevadensin) has expectorant, eliminating phlegm, softening effects. | |||
Fr13883 | 3-Methoxyphenylacetic acid | Others | |
3-Methoxyphenylacetic acid belongs to the class of organic compounds known as anisoles. 3-Methoxyphenylacetic acid is slightly soluble (in water) and a weakly acidic compound (based on its pKa).3-Methoxyphenylacetic acid... | |||
T7438 | 3,5-Dimethoxyphenol | Phloroglucinol dimethyl ether | Tyrosinase |
3,5-Dimethoxyphenol (Phloroglucinol dimethyl ether) as a marker of Taxus poisoning, being present in all species of Taxus. It has potent tyrosinase-inhibiting activity. | |||
T3999 | D(+)-Galactosamine hydrochloride | D-Galactosamine HCl | Others |
D(+)-Galactosamine hydrochloride (D-Galactosamine HCl) hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice. | |||
T8150 | Nudifloramide | 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide | PARP , Endogenous Metabolite |
Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD). | |||
T19866 | Indican | NSC-87517,3-Indoxyl-beta-D-glucopyranoside,NSC 87517,NSC87517,Indoxyl-β-D-glucoside | OAT , MRP |
Indican (Indoxyl-β-D-glucoside) is a natural protective compound that is used to protect the liver. | |||
T34295 | Resiniferatoxin | RTX,[3H]resiniferatoxin | IL Receptor |
Resiniferatoxin ([3H]resiniferatoxin) inhibits the production of Th1 cytokines, contributing to the defense against T. spiralis infection, and can be used in studies about the modulator of the immune response. | |||
T2937 | 4'-Demethylepipodophyllotoxin | 4'-DMEP,4-Demethylepipodophyllotoxin,DMEP,4'-O-demethylepipodophyllotoxin | Microtubule Associated |
4'-Demethylepipodophyllotoxin (DMEP) is a potent inhibitor of microtubule assembly. | |||
T83321 | 4-Demethyldeoxypodophyllotoxin | Chk | |
4-Demethyldeoxypodophyllotoxin, an aryl tetrahydronaphthalenyl lignan analog from the roots of Podophyllum peltatum, has anticancer activity and modulates the Chk-2 signaling pathway in MCF-7 breast cancer cells. | |||
TN1087 | Deoxypodophyllotoxin | Apoptosis , Microtubule Associated , Autophagy | |
Deoxypodophyllotoxin shows cytotoxic , antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflammatory activities. | |||
T2S0029 | 4'-Demethylpodophyllotoxin | Others | |
4'-Demethylpodophyllotoxin is isolated from the herb of Dysosma pleiantha (Hance) Woodson with remarkable cytotoxic potential in diverse cancer cell lines. | |||
TMS0418 | Dihydroergotoxine mesylate | Ergoloid mesylates | GABA Receptor |
Dihydroergotoxine mesylate (Ergoloid mesylates) is mainly used to improve symptoms and physical symptoms of mental degeneration related to aging. | |||
T0295 | Digitoxin | Digitoxoside,Unidigin,Digitoxinum | ATPase , Others |
Digitoxin (Digitoxinum) is an effective Na+/K+-ATPase inhibitor (EC50 value: 0.78 μM). | |||
T27012 | Chrysotoxine | Phenol, 4-[2-(3,4-dimethoxyphenyl)ethyl]-2,6-dimethoxy-,4-[2-(3,4-Dimethoxyphenyl)ethyl]-2,6-dimethoxyphenol | NF-κB |
Chrysotoxine (Phenol, 4-[2-(3,4-dimethoxyphenyl)ethyl]-2,6-dimethoxy-) inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via NF-κB modulation and mitochondria protection. | |||
TN7041 | (-)-Epipodophyllotoxin | Apoptosis | |
(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells with GI50s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vit... | |||
T16535 | Picrotoxinin | Chloride channel , GABA Receptor | |
Picrotoxinin is a blocker of chloride channel and a noncompetitive antagonist of GABAA with an IC50 of 1.15 μM for α1β2γ2L GABAA. Picrotoxinin shows convulsant properties. | |||
T3S0027 | Picropodophyllotoxin | AXL 1717,Picropodophyllin | IGF-1R |
Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti... | |||
TN2356 | Tetradehydropodophyllotoxin | Dehydropodophyllotoxin | Others , Antifungal |
Tetradehydropodophyllotoxin (Dehydropodophyllotoxin) has anti-tumor activity. | |||
TN1525 | Convallatoxin | NF-κB , P-gp , PPAR | |
Convallatoxin is a natural product | |||
TN5232 | Victoxinine | Others | |
Victoxinine, the toxic metabolite, considered previously to be a unique product of Helminthosporium victoriae. | |||
T34885 | Tinyatoxin | TNX,TTN,TTX | |
Tinyatoxin is a neurotoxin that works through vanillin receptors on sensory nerves. | |||
T75722 | Chlorotoxin TFA | ||
Chlorotoxin TFA, a peptide derived from the Leiurus quinquestriatus scorpion venom, functions as a chloride channel blocker [1] and exhibits anti-cancer activity [2]. | |||
TN4134 | Gitoxin | Others | |
Gitoxin is a natural product for research related to life sciences. The catalog number is TN4134 and the CAS number is 4562-36-1. | |||
TN1694 | Gliotoxin | Apoptosis , NF-κB , Wnt/beta-catenin , COX , PKA , Antibacterial , Antifection | |
Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signaling pathway. | |||
TN4496 | Marginatoxin | Caspase , Fas/FasL | |
Marginatoxin may be a promising chemopreventive agent for treating hepatocellular carcinoma, it induces human hepatoma BEL-7402 cells apoptosis in vitro and in vivo via activation of Fas/FasL-mediated apoptotic pathway. | |||
T83322 | 4'-Demethyldehydropodophyllotoxin | ||
4'-Demethyldehydropodophyllotoxin, an aryltetralin lignan derived from the leaves of Podophyllum hexandrum, exhibits cytotoxic and antitumor activity [1]. | |||
T33033 | Lyngbyatoxin A | ||
Lyngbyatoxin A is an indole alkaloid from blue-green alga Lyngbya majuscula Gomont; responsible for dermatitis known as "swimmers' itch" in Hawaii. | |||
T13534 | Aflatoxin M1 | Others | |
Aflatoxin M1, a significant metabolite of Aflatoxin B1, is a mycotoxin synthesized by Aspergillus flavus and Aspergillus parasiticus fungi. Toxicity levels of Aflatoxins follow the order: Aflatoxin B1 > Aflatoxin M1 > Af... | |||
T33775 | Ochratoxin C | HSDB 3439 | |
Ochratoxin C is a toxic metabolite from Aspergillus orchraceus. | |||
T34536 | Satratoxin H | Satratoxin-H | |
Satratoxin H is an air- and food-borne mycotoxin, which has been implicated in human health damage. | |||
T31993 | Grayanotoxin II | G-II,Deacetylanhydroandromedotoxin,delta(sup 10 (18))-Andromedenol | |
Grayanotoxins are a group of closely related neurotoxins named after Leucothoe grayana. Extract from leaves of Ericaceae. | |||
TN4165 | Grayanotoxin I | Others | |
Grayanotoxin I is a natural product for research related to life sciences. The catalog number is TN4165 and the CAS number is 4720-09-6. | |||
T30156 | Asebotoxin III | ||
Asebotoxin III is a diterpenoid obtained from the leaves of Asebi, Pieris japonica. | |||
T36068 | Brevetoxin B | ||
Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50 = 15 nM) on neurons at the neuromuscular junct... | |||
TN4813 | Podophyllotoxin 4-O-glucoside | Others | |
Podophyllotoxin 4-O-glucoside is a natural product of Dysosma, Berberidaceae. The catalog number is TN4813 and the CAS number is 16481-54-2. Podophyllotoxin 4-O-glucoside can be used as a reference standard. | |||
TN4937 | Sambutoxin | Others | |
Sambutoxin, a new mycotoxin produced by toxic Fusarium isolates obtained from rotted potato tubers, it can cause toxic effects in rats, including body weight loss, feed refusal, hemorrhage in the stomach and intestines, ... | |||
TN1359 | Aflatoxin G1 | TNF , NF-κB | |
Aflatoxin G1 (AFG1 ), a member of the AF family with cytotoxic and carcinogenic properties, could cause DNA damage in alveolar type II (AT-II) cells and induce lung adenocarcinoma. | |||
TN3520 | Bisdethiobis(methylthio)gliotoxin | PAFR | |
Bisdethiobis(methylthio)gliotoxin is a platelet activating factor (PAF) antagonist. | |||
T10609 | Brevetoxin-3 | PbTx-3 | Others |
T75539 | Nereistoxin | ||
Nereistoxin (Nereistoxine), a neurotoxin derived from Lumbriconereis heteropoda, a marine annelid, functions by inhibiting nicotinic acetylcholine receptors [1]. | |||
T13123 | Tentoxin | Endogenous Metabolite | |
Tentoxin, a cyclic peptide produced by phytopathogenic fungi, inactivates the F1 motor in sensitive plants at nanomolar to micromolar concentrations, whereas higher concentrations surpass the natural activity of the enzy... | |||
T29599 | Acetyldigitoxin | Acylanide | |
Acetyldigitoxin is a derivative of lanatoside A or of DIGITOXIN and can be used for fast digitalization in congestive heart failure. | |||
T13535 | Aflatoxin M2 | Others | |
Aflatoxin M2 is a major metabolite of Aflatoxin B1. It is a mycotoxin produced by the fungi Aspergillus flavus and Aspergillus parasiticus. | |||
T13533 | Aflatoxin G2 | Others | |
Aflatoxin G2 is a major naturally produced aflatoxin. It is a mycotoxin produced by the fungi Aspergillus flavus and Aspergillus parasiticus. | |||
T13544 | Altertoxin I | Dihydroalterperylenol | Others |
Altertoxin I (Dihydroalterperylenol) is a quinone-type mycotoxin produced by Alternaria alternata fungi. It is mutagenic and cytotoxic and can weakly disrupt metabolic communication. | |||
TN1357 | Acetylepipodophyllotoxin | Others | |
Acetylepipodophyllotoxin has insecticidal activity. | |||
T7523 | Guanidinosuccinic acid | Others , Endogenous Metabolite | |
Guanidinosuccinic acid (GSA) has been identified as a uremic toxin, is a nitrogenous metabolite isolated in excess from serum and urine. | |||
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カタログ番号 | 製品名 | Species | Expression System |
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TMPH-00361 | Beta-mammal toxin Cn2 Protein, Centruroides noxius, Recombinant (His) | Centruroides noxius | Yeast |
Mammal beta-toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the activation voltage to more negative potentials. This toxin is active against mammals. | |||
TMPY-02953 | TEM8/ANTXR1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are ser... | |||
TMPH-03626 | Beta-mammal/insect toxin Ts1 Protein, Tityus serrulatus, Recombinant (His & Myc) | Tityus serrulatus | Baculovirus |
Beta-mammal/insect toxin Ts1 Protein, Tityus serrulatus, Recombinant (His & Myc) is expressed in Baculovirus. | |||
TMPH-03628 | Beta-toxin Tz1 Protein, Tityus zulianus, Recombinant (His & Myc) | Tityus zulianus | E. coli |
Beta-toxin Tz1 Protein, Tityus zulianus, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-03627 | Beta-mammal/insect toxin Ts1 Protein, Tityus serrulatus, Recombinant (E. coli, His & Myc) | Tityus serrulatus | E. coli |
Beta-mammal/insect toxin Ts1 Protein, Tityus serrulatus, Recombinant (E. coli, His & Myc) is expressed in E. coli. | |||
TMPH-00432 | Diphtheria toxin Protein, Corynephage omega, Recombinant (His & Myc) | Corynephage omega | E. coli |
Diphtheria toxin Protein, Corynephage omega, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-03625 | Alpha-mammal toxin Ts2 Protein, Tityus serrulatus, Recombinant (His & Myc) | Tityus serrulatus | Baculovirus |
Alpha-mammal toxin Ts2 Protein, Tityus serrulatus, Recombinant (His & Myc) is expressed in Baculovirus. | |||
TMPH-00362 | Beta-mammal toxin Css4 Protein, Centruroides suffusus, Recombinant (His & SUMO) | Centruroides suffusus | E. coli |
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repe... | |||
TMPJ-00744 | Toxin B Protein, Vibriocholerae, Recombinant | Vibrio cholerae | E. coli |
Cholera toxin is protein complex secreted by the bacterium Vibrio cholerae. It is responsible for the massive, watery diarrhea characteristic of cholera infection. Cholera enterotoxin subunit B (CTXB) pentameric ring dir... | |||
TMPH-00054 | AaH II Protein, Androctonus australis, Recombinant (His & SUMO) | Androctonus australis | E. coli |
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. The toxin principally slows the inactivation proc... | |||
TMPH-03523 | Alpha-hemolysin Protein, S. aureus, Recombinant (His & SUMO) | Staphylococcus aureus | E. coli |
Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probabl... | |||
TMPH-03522 | Alpha-hemolysin Protein, S. aureus, Recombinant (His) | Staphylococcus aureus | Yeast |
Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probabl... | |||
TMPH-03075 | 3FTx-Oxy6 Protein, Oxyuranus microlepidotus, Recombinant (His & Myc & SUMO) | Oxyuranus microlepidotus | E. coli |
3FTx-Oxy6 Protein, Oxyuranus microlepidotus, Recombinant (His & Myc & SUMO) is expressed in E. coli. | |||
TMPH-03586 | Toxin zeta Protein, S. agalactiae, Recombinant (His) | Streptococcus agalactiae | Yeast |
Toxic component of a type II toxin-antitoxin (TA) system. Phosphorylates UDP-N-acetyl-D-glucosamine (UNAG) on the 3'-hydroxyl group of the N-acetyl-D-glucosamine moiety, yielding UNAG-3P. UNAG-3P inhibits MurA, the first... | |||
TMPH-03026 | CARDS Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) | Mycoplasma pneumoniae | E. coli |
Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of... | |||
TMPH-00403 | Toxin A Protein, Clostridioides difficile, Recombinant (His) | Clostridioides difficile | E. coli |
Toxin A Protein, Clostridioides difficile, Recombinant (His) is expressed in E. coli. | |||
TMPH-03551 | Exfoliative toxin A Protein, S. aureus, Recombinant (His) | Staphylococcus aureus | E. coli |
Has serine protease-like properties and binds to the skin protein profilaggrin. Cleaves substrates after acidic residues. Exfoliative toxins cause impetigous diseases commonly referred as staphylococcal scalded skin synd... | |||
TMPH-00837 | BjaIT Protein, Hottentotta judaicus, Recombinant (His & Myc) | Hottentotta judaicus | E. coli |
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active against insects (para/tipE). | |||
TMPH-03534 | Delta-hemolysin Protein, S. aureus, Recombinant (His & KSI) | Staphylococcus aureus | E. coli |
Lyses erythrocytes and many other mammalian cells. | |||
TMPH-00423 | Tetanus toxin Protein, Clostridium tetani, Recombinant (B2M & His) | Clostridium tetani | E. coli |
Tetanus toxin Protein, Clostridium tetani, Recombinant (B2M & His) is expressed in E. coli. | |||
TMPH-00056 | Delta-AITX-Avd1c Protein, Anemonia sulcata, Recombinant (His) | Anemonia sulcata | Yeast |
Binds specifically to voltage-gated sodium channels (Nav) (site 3), thereby delaying their inactivation. Has a strong effect on crustaceans and insects (DmNav1) and a weaker effect on mammals. This toxin is highly potent... | |||
TMPH-00604 | CDTA Protein, E. coli, Recombinant (His) | E. coli | E. coli |
CDTs are cytotoxins which induce host cell distension, growth arrest in G2/M phase, nucleus swelling, and chromatin fragmentation in HeLa cells. CdtA, along with CdtC, probably forms a heterodimeric subunit required for ... | |||
TMPH-00606 | CDTC Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Part of the tripartite complex that is required for the CDT activity. CdtC, along with CdtA, probably forms a heterodimeric subunit required for the delivery of CdtB. | |||
TMPY-00380 | ANTXR2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Loss-of-function mutations in capillary morphogenesis gene 2 (CMG2/ANTXR2), a transmembrane surface protein, cause hyaline fibromatosis syndrome (HFS), a severe genetic disorder that is characterized by large subcutaneou... | |||
TMPH-00387 | Toxin CfTX-1 Protein, Chironex fleckeri, Recombinant (His & SUMO) | Chironex fleckeri | E. coli |
May cause profound effects on the cardiovascular system of anesthetized rats (at 25 ug/kg), since the fraction containing this toxin and CfTX-2 produces an initial increase in mean arterial pressure, followed by cardiova... | |||
TMPH-03552 | Exfoliative toxin B Protein, S. aureus, Recombinant (His & Myc) | Staphylococcus aureus | E. coli |
Has serine protease-like properties and binds to the skin protein profilaggrin. Cleaves substrates after acidic residues. Exfoliative toxins cause impetigous diseases commonly referred as staphylococcal scalded skin synd... | |||
TMPH-00055 | Alpha-toxin Amm8 Protein, Androctonus mauritanicus, Recombinant (His & Myc) | Androctonus mauritanicus | Baculovirus |
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. The toxin principally slows the inactivation proc... | |||
TMPY-00615 | ANTXR2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Loss-of-function mutations in capillary morphogenesis gene 2 (CMG2/ANTXR2), a transmembrane surface protein, cause hyaline fibromatosis syndrome (HFS), a severe genetic disorder that is characterized by large subcutaneou... | |||
TMPH-03652 | Ustilago maydis P6 virus (UmV6) KP6 killer toxin (His) | UmV6 | Yeast |
Ustilago maydis P6 virus (UmV6) KP6 killer toxin (His) is expressed in Yeast. | |||
TMPY-04094 | ANTXR2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Loss-of-function mutations in capillary morphogenesis gene 2 (CMG2/ANTXR2), a transmembrane surface protein, cause hyaline fibromatosis syndrome (HFS), a severe genetic disorder that is characterized by large subcutaneou... | |||
TMPH-00605 | CDTB Protein, E. coli, Recombinant (His & Myc & SUMO) | E. coli | E. coli |
Part of the tripartite complex that is required for the CDT activity. CdtB exhibits a DNA-nicking endonuclease activity, and very probably causes DNA damage in intoxicated cells. This damage induces G2/M cell cycle arres... | |||
TMPJ-01333 | TEM8/ANTXR1 Protein, Human, Recombinant (His) | Human | Human Cells |
Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothel... | |||
TMPY-02447 | Shiga toxin II subunit B Protein, E. coli, Recombinant (His) | E. coli | E. coli |
E. Coli STX2B is a subunit of Stx2. Stx2, together with Stx1, formed a family of related toxins which are known as shiga toxins. Shiga toxins are mainly produced by the bacteria S. dysenteriae and the Shigatoxigenic grou... | |||
TMPH-00510 | DT3C Protein, Recombinant (His) | Corynephage beta | E. coli |
DT3C Protein, Recombinant (His) is expressed in E. coli. | |||
TMPY-02439 | Rac2 Protein, Human, Recombinant (His) | Human | E. coli |
Ras-related C3 botulinum toxin substrate 2 (Rac2) is a small G-protein belonging to the Ras subfamily of the GTPase family. Rac2 acts as an "on / off" switch for signal transduction cascades and motilities. When GDP is a... | |||
TMPY-01187 | Rac1 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
RAC1 is a GTPase that belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal re... | |||
TMPJ-01286 | ProHB-EGF Protein, Human, Recombinant (His) | Human | Human Cells |
Heparin-binding EGF-like growth factor (HB-EGF) is a 1216 kDa member of the epidermal growth factor (EGF) family. It possesses an EGFlike domain, and a heparin-binding motif. Mature HBEGF is a soluble peptide that ari... | |||
TMPH-00632 | Heat-labile enterotoxin B chain Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase. | |||
TMPH-00630 | Heat-labile enterotoxin A chain Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase. | |||
TMPH-00631 | Heat-labile enterotoxin B chain Protein, E. coli, Recombinant (His) | E. coli | E. coli |
The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase. | |||
TMPH-00579 | Antitoxin RelB Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Antitoxin component of a type II toxin-antitoxin (TA) system. Counteracts the effect of cognate toxin RelE via direct protein-protein interaction, preventing RelE from entering the ribosome A site and thus inhibiting its... | |||
TMPH-00633 | Heat-stable enterotoxin A2 Protein, E. coli, Recombinant (His & Myc & SUMO) | E. coli | E. coli |
Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells. | |||
TMPH-00635 | Heat-stable enterotoxin ST-IA/ST-P Protein, E. coli, Recombinant (GST) | E. coli | E. coli |
Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells. | |||
TMPH-00634 | Heat-stable enterotoxin ST-2 Protein, E. coli, Recombinant | E. coli | E. coli |
Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells. | |||
TMPH-00818 | Delta-theraphotoxin-Hm1a Protein, Heteroscodra maculata, Recombinant (His & Myc & SUMO) | Heteroscodra maculata | E. coli |
Gating-modifier toxin that potently inhibits inactivation of the mammalian Nav1.1/SCN1A sodium channel (EC(50)=38 nM). Also moderately inhibits inactivation of Nav1.2/SCN2A (EC(50)=236 nM) and Nav1.3/SCN3A (EC(50)=220 nM... | |||
TMPH-03544 | Enterotoxin type D Protein, S. aureus, Recombinant (His & SUMO) | Staphylococcus aureus | E. coli |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a... | |||
TMPH-03710 | Viscotoxin-A3 Protein, Viscum album, Recombinant (His & SUMO) | Viscum album | E. coli |
Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. Their precise function is not known. | |||
TMPH-03035 | M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His) | Myrmecia pilosula | Baculovirus |
Heterodimer protein that may serve both defensive (pain-inducing) and predatory (insecticidal) roles. Has membrane-disrupting activity and shows induction of non-specific calcium influx into cells,. Shows broad-spectrum ... | |||
TMPY-00248 | Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His) | Cynomolgus | Baculovirus-Insect Cells |
LTB (Lymphotoxin Beta) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surfa... | |||
TMPH-03541 | Enterotoxin type C-2 Protein, S. aureus, Recombinant (His & SUMO) | Staphylococcus aureus | E. coli |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a... | |||
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