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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T25450 | GGTI 2147 | GGTI2147,Geranylgeranyl transferase inhibitor-2147,GGTI-2147 | NF-κB , Rho |
GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis. | |||
T82343 | Gamma-Glutamyl Transferase-IN-1 | ||
Gamma-Glutamyl Transferase-IN-1 (compound 4de), a β-carboline 1-hydrazide inhibitor, exhibits antifungal and antibacterial properties by targeting glutamyltransferase. Its mechanism of action involves inducing the accumu... | |||
T82342 | Gamma-Glutamyl Transferase-IN-2 | ||
Gamma-Glutamyl Transferase-IN-2 (compound 4dq), a β-carboline 1-hydrazide inhibitor, exhibits both antifungal and antibacterial properties by targeting glutamyltransferase. Its mode of action includes inducing reactive o... | |||
T11282 | FGTI-2734 | Transferase | |
T9626 | Cycloleucine | NMDAR | |
Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 μM. Cycloleucine is also a competitive inhibitor of S-adenosyl-methionine mediated methylation with anxiolytic and cytostatic ef... | |||
T11505 | GSTO1-IN-1 | Glutathione Peroxidase , GST | |
GSTO1-IN-1 is a potent glutathione S-transferase omega 1 inhibitor (GSTO1; IC50: 31 nM). | |||
T6302 | Lonafarnib | Sarasar,Sch66336 | Raf , Transferase , Autophagy , Ras |
Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM). | |||
T2678 | LB42708 | Transferase | |
T4335 | GNE-617 | GNE617 | NAMPT |
GNE-617, a specific NAMPT inhibitor(IC50=5 nM), shows potency in xenograft models of cancer. | |||
T6682 | STF-118804 | STF 118804,STF118804 | Apoptosis , NAMPT |
STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM. | |||
T12171 | Nampt-IN-5 | P450 , NAMPT | |
Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) . | |||
T3182 | L-778123 hydrochloride | L 778123 | Telomerase , Transferase |
The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination. | |||
T4376 | Nampt-IN-1 | LSN3154567 | c-Fms , NAMPT , CSF-1R |
Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM. | |||
T2700 | FTI-277 hydrochloride | FTI 277 HCl | Apoptosis , Transferase , Ras |
FTI-277 hydrochloride (FTI 277 HCl) is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM); this selectivity is about 100-fold than the closely related GGTase I. | |||
T6271 | Tipifarnib | R115777,Zarnestra,IND 58359 | Transferase |
Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnes... | |||
T16409 | OSMI-1 | Others , Acyltransferase | |
OSMI-1 is an O-GlcNAc transferase (OGT) inhibitor (IC50=2.7 μM) that is orally active and cell-permeable. OSMI-1 inhibits protein O-GlcNA acetylation without qualitatively altering cell-surface N- or O- linked glycans. | |||
T38050 | CP-609754 | Transferase | |
CP-609754 (LNK-754) is a potent and reversible farnesyltransferase inhibitor with potential anticancer activity.The IC50 for inhibiting farnesylation of recombinant human H-Ras is 0.57 ng/mL and recombinant K-Ras is 46 n... | |||
T4564 | Ethacrynic acid | Edecrin,Etacrynic Acid,Hydromedin | Others , Calcium Channel , NF-κB , GST |
Ethacrynic acid (Edecrin) is a nonsulfonamide loop diuretic that inhibits the activity of the Na+/K+/2Cl- cotransporter NKCC2 in the thick ascending limb of the loop of Henle. It also inhibits glutathione S-transferase a... | |||
T1998 | CHS-828 | CHS 828,GMX1778 | Apoptosis , NAMPT |
CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM). | |||
T22665 | PD 128042 | CI 976 | Acyltransferase |
PD 128042 (CI 976) is a potent orally active and selective ACAT inhibitor(IC50: 73 nM) and a potent lysophospholipid acyltransferase(LPAT) inhibitor. CI 976 inhibits Golgi-associated LPAT activity (IC50: 15 μM) and multi... | |||
T5097 | Ezatiostat | TER199(free base),TLK199 | Apoptosis , Glutathione Peroxidase , GST |
Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity. | |||
T12854 | SBI-797812 | NAMPT | |
SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM). | |||
T17102 | Tipifarnib (S enantiomer) | Tipifarnib S enantiomer,(S)-(-)-R-115777,(S)-Tipifarnib,IND-58359 S enantiomer | Transferase |
Tipifarnib S enantiomer ((S)-(-)-R-115777) is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase inhibitor (IC50: 0.6 nM). | |||
T2644 | (E)-Daporinad | Daporinad,(E)-N-[4-(1-BENZOYL-PIPERIDIN-4-YL)-BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE,APO866,FK866 | NAMPT , Transferase , Autophagy |
(E)-Daporinad (FK866) is a small molecule inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase), with potential antineoplastic and antiangiogenic activities. | |||
T22776 | Ezatiostat hydrochloride | TLK199 HCl,TER199 | Glutathione Peroxidase |
Ezatiostat hydrochloride (TLK199 HCl) is an effective inhibitor of glutathione S-transferase. Ezatiostat hydrochloride is a novel glutathione analog and the potential treatment of cytopenias. In addition, Ezatiostat hydr... | |||
T61037 | Glycosyltransferase-IN-1 | Others | |
Glycosyltransferase-IN-1 is a glycosyltransferase inhibitor with bacteriostatic activity, inhibiting MSSA, MRSA, Bacillus subtilis, and Enterobacteriaceae. | |||
T77560 | Histone acetyltransferase p300 Inhibitor 4c | Carbonic Anhydrase , AChE | |
Histone acetyltransferase p300 Inhibitor 4c is a 2-aminothiazole derivative. Histone acetyltransferase p300 Inhibitor 4c inhibited hCA I, hCA II, AChE and BChE with Ki values of 0.008 ± 0.001, 0.124 ± 0.017, 0.129 ± 0.03... | |||
T11563 | Histone Acetyltransferase Inhibitor II | Epigenetic Reader Domain , Histone Acetyltransferase | |
Histone Acetyltransferase Inhibitor II is a selective and cell permeable inhibitor of p300 histone acetyltransferase(IC50 : 5 μM).with anti-acetylase activity in mammalian cells. | |||
T75416 | Alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) | ||
Alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) (EC 2.4.1.40(Pm1138)), also known as the ABO system transferase, exhibits glycosyl transferase activity [1]. | |||
T76158 | Phosphate acetyltransferase | ||
Phosphate acetyltransferase, a transferase enzyme utilized in biochemical research, catalyzes the reversible acetylation of CoA from acetyl-P, yielding acetyl-CoA and inorganic phosphate. This process is integral to acet... | |||
T63738 | Purine phosphoribosyltransferase-IN-2 | ||
Purine phosphoribosyltransferase-IN-2 is a potent inhibitor of Plasmodium falciparum (Pf), Plasmodium vivax (Pv), and Trypanosoma brucei (Tbr) 6-oxopurine phosphoribosyltransferase (PRT) with Ki values of 30, 20, and 2 n... | |||
T75399 | GlcNAc 1-P uridyltransferase (CjGlmU) | ||
GlcNAc 1-P uridyltransferase (CjGlmU), a sugar nucleotidyltransferase (SNT), employs UTP and GlcNAc-1-P to synthesize UDP-GlcNAc, with potential implications in antimicrobial agent research [1]. | |||
T75418 | Alpha-1,3-Galactosyltransferase (GTB) | ||
Alpha-1,3-Galactosyltransferase (GTB) (alpha 1,3GT) is responsible for catalyzing the synthesis of the α-galactose (α-Gal) epitope, known as a xenoantigen. This enzyme facilitates the transfer of galactose from UDP-Gal t... | |||
T75413 | Beta-1,4-Galactosyltransferase (LgtB) | ||
Beta-1,4-Galactosyltransferase (LgtB) (B4GALT1(LgtB)), a key enzyme in biochemical research, catalyzes the transfer of UDP-galactose to N-acetylglucosamine, resulting in the synthesis of galactose beta-1,4-N-acetylglucos... | |||
T75419 | Alpha-2,8-Sialyltransferase (CstII) | ||
Alpha-2,8-Sialyltransferase (CstII) (ST8Sia VI), belonging to the alpha2,8-sialyltransferase (ST8Sia) family, primarily catalyzes the elongation of the α2,8-linked oligo/polysialic acid chain on the sialic acid (Sia) res... | |||
T75421 | Alpha-2,3-Sialyltransferase (PmST3) | ||
alpha-2,3-Sialyltransferase (PmST3) is a beta-galactoside. alpha-2,3-Sialyltransferase (PmST3) catalyzes the transfer of sialic acid to carbohydrate groups of glycoproteins and glycolipids [1] . | |||
T63737 | Purine phosphoribosyltransferase-IN-1 | ||
Purinephosphoribosyltransferase-IN-1 (Compound (S,R)-48) is a potent inhibitor of Plasmodium falciparum (Pf), Plasmodium vivax (Pv) and Trypanosoma brucei (Tbr) 6-oxopurine phosphate ribosyltransferase (PRT) with Ki valu... | |||
T75411 | Beta-1, 3-N-Acetylhexaminyltransferase (LgtA) | ||
Beta-1, 3-N-Acetylhexaminyltransferase (LgtA), a glycosyltransferase, plays a critical role in biochemical studies by catalyzing the transfer of N-acetylglucosamine from UDP-GlcNAc to substrates including N-acetyllactosa... | |||
T75414 | Alpha-1,4-Galactosyltransferase (LgtC) | ||
Alpha-1,4-Galactosyltransferase (LgtC) (A4GALT), a glycosphingolipid-specific glycosyltransferase, catalyzes the transfer of a galactose molecule to the alpha-1,4 position on lactosylceramide, resulting in the formation ... | |||
T75415 | Beta-1,3-Galactosyltransferase (CgtB) | ||
Beta-1,3-Galactosyltransferase (CgtB) (GM1-synthase), an enzyme critical for the production of sialylated lipooligosaccharide (LOS SIAL), plays a key role in biochemical research. This enzyme facilitates the incorporatio... | |||
T11037 | Diacylglycerol acyltransferase inhibitor-1 | Others | |
Diacylglycerol Acyltransferase Inhibitor-1, a diacylglycerol acyltransferase (DGAT1) inhibitor, effectively suppresses the activity of DGAT1. | |||
T13429 | α-2,3-sialyltransferase-IN-1 | Lith-O-Asp analog | Others |
α-2,3-sialyltransferase-IN-1 is a noncompetitive inhibitor of α-2,3-sialyltransferase(IC50 of 6 μM). | |||
T78353 | Alpha-2,6-Sialyltransferase (Pd26ST) | ||
Alpha-2,6-Sialyltransferase (Pd26ST) efficiently catalyzes the sialylation of both terminal and internal galactose and N-acetylgalactosamine residues, resulting in the production of terminal α2,6-sialosides [1]. | |||
T78364 | Alanine aminotransferase | Endogenous Metabolite | |
Alanine aminotransferase (ALT), a pyridoxal-dependent enzyme, catalyzes the reversible interconversion of L-alanine and 2-oxoglutarate into pyruvate and L-glutamate [1]. | |||
T78352 | N-acetylglucosamine-1-P uridyltransferase (AGX1) | GlcNAc1pUT | |
N-acetylglucosamine-1-P uridyltransferase (AGX1) (GlcNAc1pUT) is a bifunctional enzyme that couples with GlcNAc-1-P and UTP to catalyze the synthesis of UDP-GlcNAc through an uridyltransfer reaction. It exhibits acetyltr... | |||
T75420 | Alpha-1,3/4-Fucosyltransferase (α1,3/4FucT) | ||
alpha-1,3/4-Fucosyltransferase (α1,3/4FucT) (Hp3/4FT) can be found in Helicobacter pylori . alpha-1,3/4-Fucosyltransferase (α1,3/4FucT) catalyzes fucose transfer from donor GDP-beta-l-fucose to the GlcNAc [1] . | |||
T75417 | Alpha-1,3-Galactosyltransferase (a1,3GalT) | ||
Alpha-1,3-Galactosyltransferase (a1,3GalT) (GGTA1) catalyzes the synthesis of the α-gal epitope by transferring a galactose (Gal) molecule in an α1-3 linkage from a uridyl-diphosphate (UDP) donor to the N-acetyllactosami... | |||
T76178 | Aspartate aminotransferase | ||
Aspartate aminotransferase (AST) is a transaminase enzyme, is often used in biochemical studies. Aspartate aminotransferase catalyzes aspartate and alpha-ketoglutarate converts to oxaloacetate and glutamate. Aspartate am... | |||
T75389 | Catechol O-methyltransferase | ||
Catechol O-methyltransferase (COMT) is a magnesium-dependent enzyme that mediates the transfer of methyl groups from S-adenosyl methionine to the hydroxyl group on dopamine, thus converting it to 3-methoxytyramine. COMT ... | |||
T3499 | Remodelin | Histone Acetyltransferase | |
Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN6512 | Tectol | Transferase , Parasite | |
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatiti... | |||
TQ0165 | Arglabin | (+)-Arglabin | NOD-like Receptor (NLR) , Transferase , NOD , Autophagy |
Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects. | |||
T3S0012 | Coniferyl ferulate | P-gp , GST | |
Coniferyl ferulate is a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis. It shows strong inhibition of human placental GST (IC50: 0.3 μM). It also reverses multidrug resistance ... | |||
TN1078 | Seneciphylline | P450 , GST | |
Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer into rat milk.Seneciphylline can significantly increased the activities of epoxide hydrase and glutat... | |||
T7995 | α-Angelica lactone | Alpha-Angelica Lactone | Others , GST |
α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization. | |||
T3S0541 | Curzerene | Apoptosis , GST | |
Curzerene, a sesquiterpene compound derived from the rhizome of Curculigo orchioides Gaertn, possesses potent anti-cancer properties. It is known to induce apoptosis in cells[1] and also suppress the expression of glutat... | |||
TN3270 | (R)-3β-Hydroxy steroid sulfotransferase-IN-11 | Others | |
(R)-3β-Hydroxy steroid sulfotransferase-IN-11 has a wide range of applications in life science related research. | |||
TN1474 | Caulilexin C | Others , Antifungal | |
Caulilexin C shows inhibitory activity on human Acyl CoA: cholesterol transferase I (hACATI) and on human Acyl CoA: cholesterol transferase 2 (hACAT2) at 100 mug/ml. | |||
T3314 | Perillyl alcohol | Isocarveol,Perilla alcohol | Apoptosis , Endogenous Metabolite |
Perillyl Alcohol is a naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol (Isocarveol) inhibits farnesyl transferase and geranylgeranyl transferase, thereby preventing post-... | |||
TJS0405 | Lucidin | NSC 30546,Henine | Others |
1. Lucidin (NSC-30546) and its derivatives are genotoxic, it is mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus. | |||
T5654 | Musk ketone | Others | |
Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant. | |||
T6758 | Anisomycin | Flagecidin,NSC 76712,Wuningmeisu C | Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , JNK |
Anisomycin (NSC-76712) is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. | |||
T3S0218 | Thonningianin A | Apoptosis , Others | |
1. Thonningianin A has anti-cancer activities.2. Thonningianin A represents a new potent glutathione S-transferase in vitro inhibitor.3. Thonningianin A has antioxidant property, involves radical scavenging, anti-superox... | |||
T11680 | Isoasatone A | P450 | |
Isoasatone A is a natural product isolated from the plant Heterotropa takaoi M., with anti-insect activity. | |||
T6S0071 | Fraxinellone | HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1 | |
1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding... | |||
T4848 | Mandelic acid | acidomandelico,DL-Mandelic acid | Others , Endogenous Metabolite , Antibacterial |
It is an isomer of cresotinic acid (2-hydroxy-3-methylbenzoic acid) and oxymethylbenzoic acid (2-methoxybenzoic acid). Derivatives of mandelic acid are formed as a result of metabolism of adrenaline and noradrenaline by ... | |||
T24412 | Lipoxamycin | G 26146,G-26146,G26146,Neoenactin M1 | |
Lipoxamycin is an inhibitor of serine palmitoyl-transferase. | |||
T11842 | Levomecol | Others | |
Levomecol, a broad-spectrum antibiotic derived from Streptomyces venezuelae, comprises Chloramphenicol and Methyluracil. It exerts its bacteriostatic effect by binding to the bacterial ribosome, inhibiting protein synthe... | |||
TN2849 | 3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid | Antifection | |
2-O-beta-d-Glucosyloxy-4-methoxybenzenepropanoic acid[3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid] exhibits glutathione S-transferase (GST) inhibitory and antifungal activities. | |||
TN4443 | Lipiferolide | Telomerase , Antifection | |
Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibitory activity against several tumor cells, it possesses cytoto... | |||
TN2834 | 27-p-Coumaroyloxyursolic acid | Others | |
27-trans-p-Coumaroyloxyursolic acid and 27-cis-p-coumaroyloxyursolic acid show potent inhibitory activity in the acyl CoA cholesteryl acyl transferase (ACAT) assay. | |||
T29329 | 24-Methylenecholesterol | 24Methylenecholesterol,24 Methylenecholesterol,Chalinasterol,Ostreasterol | Acyltransferase |
24-Methylenecholesterol (24 Methylenecholesterol) is a natural marine sterol, which stimulates cholesterol acyl transferase (ACAT) in human macrophages. | |||
TN4345 | Jacobine | Others | |
Jacobine induces significant dose-dependent DNA-DNA interstrand cross-linking over the entire range of doses. It was catalyzed by guinea pig hepatic glutathione-S-transferase enzymes in in vitro experiments. | |||
T75696 | Ilexoside XLVIII | ||
Ilexoside XLVIII, a triterpene saponin isolated from the aqueous extract of Ilex kudincha leaves [1], functions as an acyl CoA cholesteryl acyl transferase (ACAT) inhibitor. | |||
T11202 | Enniatin complex | Others | |
Enniatin complex, a mixture of cyclohexadepsipeptides predominantly derived from various Fusarium species of fungi, exhibits inhibitory effects on enzymes such as acyl-CoA: cholesterol acyl transferase. Furthermore, it h... | |||
T13053 | T-2 Toxin | T-2 Mycotoxin | Apoptosis , ROS , DNA/RNA Synthesis |
T-2 Toxin (T-2 Mycotoxin) is a fungal secondary metabolite produced by various Fusarium species in feed and grains, which is highly toxic to reproduction and induces a variety of cardiovascular toxicities.T-2 Toxin is an... | |||
T38299 | Tunicamycin V | ||
Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contains a 15-carbon N-acyl chain with variable branching patterns.References Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that cont... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-00539 | GSTA1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) ... | |||
TMPH-00164 | 4'-phosphopantetheinyl transferase ffp Protein, Bacillus subtilis, Recombinant (His & Myc) | Bacillus subtilis | E. coli |
May activate the peptidyl carrier protein (PCP) domains of fengycin synthase by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. 4'-phosphopantetheinyl transferase ffp Protein, Baci... | |||
TMPH-00569 | AtoD Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
N/A. atoD Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.5 kDa and the accession number is P76458. | |||
TMPY-00027 | GSTT2B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
GSTT2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29 kDa and the accession number is P0CG29. | |||
TMPY-03338 | GSTZ1 Protein, Human, Recombinant (His) | Human | E. coli |
GSTZ1 (Glutathione S-Transferase Zeta 1) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. GSTZ1 gene is a member of the glutathione S-transferase (GSTs) super-family which encodes mult... | |||
TMPY-03332 | PRTFDC1 Protein, Human, Recombinant (His) | Human | E. coli |
PRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG ... | |||
TMPY-03450 | GSTK1 Protein, Human, Recombinant | Human | E. coli |
GSTK1 gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. Glutathione S-transferases (GSTs) are a family of enzymes that catalyze a var... | |||
TMPH-00406 | CtfB Protein, Clostridium acetobutylicum, Recombinant (His & Myc) | Clostridium acetobutylicum | E. coli |
Involved in solventogenic switch which allows C.acetobutylicum to uptake acid and produce solvents. Acts mainly to detoxify the medium by removing the acetate and butyrate excreted earlier in the fermentation. ctfB Prote... | |||
TMPY-01554 | GSTM5 Protein, Human, Recombinant (His) | Human | E. coli |
GSTM5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 27.9 kDa and the accession number is AAH58881.1. | |||
TMPH-02379 | ArnT Protein, Klebsiella pneumoniae, Recombinant (His) | Klebsiella pneumoniae | E. coli |
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antim... | |||
TMPY-02223 | GSTM2 Protein, Human, Recombinant (His) | Human | E. coli |
Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-te... | |||
TMPJ-00611 | SFP Protein, B.subtilis, Recombinant (His) | Bacillus subtilis | E. coli |
The Bacillus subtilis enzyme Sfp, required for production of the lipoheptapeptide antibiotic surfactin, posttranslationally phosphopantetheinylates a serine residue in each of the seven peptidyl carrier protein domains o... | |||
TMPH-03438 | CHS1 Protein, S. cerevisiae, Recombinant (His) | Saccharomyces cerevisiae | E. coli |
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. Required for mitotic division septum formation d... | |||
TMPJ-00499 | GSTP1 Protein, Human, Recombinant | Human | E. coli |
Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in deto... | |||
TMPJ-00765 | TDT Protein, Human, Recombinant (His) | Human | E. coli |
Terminal deoxynucleotidyl transferase (TdT) is a highly conserved vertebrate enzyme that possesses the unique ability to catalyze the random addition of deoxynucleoside 5'-triphosphates onto the 3'-hydroxyl group of a si... | |||
TMPH-00017 | AcpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc) | Acholeplasma laidlawii | E. coli |
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. acpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc... | |||
TMPK-01001 | RNF43 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/β-catenin signaling pathway. RNF43 i... | |||
TMPJ-01302 | ACAT2 Protein, Human, Recombinant (His) | Human | E. coli |
ACAT2 is a cytoplasmic enzyme which belongs to the thiolase family. ACAT2 takes part in lipid metabolism, lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. It is responsible for the synthesi... | |||
TMPH-02628 | Cathepsin C Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase. Can degrade glucagon. Plays a role in the generation of cytotoxic lymphocyte effector function. | |||
TMPH-03448 | EHT1 Protein, S. cerevisiae, Recombinant (His) | Saccharomyces cerevisiae | E. coli |
Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity). MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by est... | |||
TMPJ-01115 | GALNT3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Polypeptide N-acetylgalactosaminyltransferase 3(GALNT3) belongs to the glycosyltransferase 2 family and galNAc-T subfamily. It expressed in organs that contain secretory epithelial glands and it highly expressed in pancr... | |||
TMPJ-01223 | GALNTL1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Putative polypeptide N-acetylgalactosaminyltransferase-like protein 1, also known as Polypeptide GalNAc transferase-like protein 1, Protein-UDP acetylgalactosaminyltransferase-like protein 1, UDP-GalNAc:polypeptide N-ace... | |||
TMPJ-00690 | PGDS Protein, Human, Recombinant | Human | E. coli |
Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macroph... | |||
TMPY-05693 | SARS-CoV-2 Methyltransferase/ME Protein (His) | SARS-CoV-2 | E. coli |
Coronavirus encodes the 2’-O-MTase (2'O Methyltransferase) that is composed of the catalytic subunit nsp16 and the stimulatory subunit nsp10 and plays an important role in virus genome replication and evasion from innate... | |||
TMPH-00573 | DAPA aminotransferase Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM a... | |||
TMPY-00279 | Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His) | DENV | E. coli |
Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35.5 kDa and the ac... | |||
TMPH-03604 | Phosphinothricin N-acetyltransferase Protein, Streptomyces hygroscopicus, Recombinant (His) | Streptomyces hygroscopicus | E. coli |
Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA. Can also acetylate demethylphosphinothricin but not PTT or glutamate. This enzyme is an effector of phosphinothricin tripeptide (PTT or b... | |||
TMPH-03608 | Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His) | Streptomyces viridochromogenes | P. pastoris (Yeast) |
Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA. This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Phosphinothricin N-acetyltransferase Protein, S.... | |||
TMPY-03445 | Aspartate Aminotransferase Protein, Human, Recombinant (His) | Human | E. coli |
GOT1 (Glutamic-Oxaloacetic Transaminase 1) is a Protein Coding gene. GOT1 belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent... | |||
TMPJ-01429 | SARS-CoV-2 Guanine-N7 methyltransferase Protein (His) | SARS-CoV-2 | E. coli |
The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and ds... | |||
TMPH-00313 | TRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His) | Brugia malayi | E. coli |
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. tRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. ... | |||
TMPH-03609 | Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His & SUMO) | Streptomyces viridochromogenes | E. coli |
Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA. This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Phosphinothricin N-acetyltransferase Protein, S.... | |||
TMPH-03600 | Glucosyltransferase-SI Protein, S. mutans serotype c, Recombinant (His & Myc) | Streptococcus mutans | E. coli |
Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and fo... | |||
TMPY-02279 | Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His) | Human | E. coli |
Purine nucleoside phosphorylase (PNP) is a purine-metabolizing enzyme that catalyzes the reversible phosphorolysis of 6-oxypurine (deoxy)nucleosides to their respective bases and (deoxy)ribose-1-phosphate. It is a key en... | |||
TMPY-00365 | GALNT7 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
GalNAc-transferase-7 (GALNT7) is essential for the regulation of cell proliferation and has been implicated in tumorigenesis. Colorectal cancer (CRC) arises in a multistep molecular network process, which is from either ... | |||
TMPY-02157 | GST Protein, Schistosoma japonicum, Recombinant | Schistosoma japonicum | Baculovirus Insect Cells |
Genetic engineers have used glutathione S-transferase to create the GST gene fusion system. This system is used to purify and detect proteins of interest. In a GST gene fusion system, the GST sequence is incorporated int... | |||
TMPH-00893 | AHCY Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the... | |||
TMPJ-00087 | VMO1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Vitelline membrane outer layer protein 1 homolog (VMO1) belongs to the VMO1 family is a 202 amino acid secreted protein. Exact function not known, component of the outer membrane of the vitelline layer of the egg. Seems ... | |||
TMPY-01856 | MGAT5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, also known as Alpha-mannoside beta-1,6-N-acetylglucosaminyl-transferase, Mannoside acetylglucosaminyltransferase 5, N-acetylglucosaminyl-transferas... | |||
TMPH-01397 | LANCL1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during norma... | |||
TMPJ-00053 | PRL-2 Protein, Human, Recombinant (His) | Human | E. coli |
PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational ... | |||
TMPY-02596 | GLT25D2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Glycosyl transferase 25 domain 2 (GLT25D2) is a glucosyltransferase enzyme expressed only at low levels in the nervous system. Glycosyltransferases are enzymes that act as a catalyst for the transfer of a monosaccharide ... | |||
TMPY-02421 | PARP3 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Poly(ADP-ribose) polymerase 3 (PARP3) is an important member of the PARP family and shares high structural similarities with both PARP1 and PARP2. Poly(ADP-ribose) polymerase 3 (PARP3), a critical player in cellular resp... | |||
TMPY-02640 | FAM3B Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Pancreatic derived factor, also known as FAM3B, is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B protein is present in alpha- and b... | |||
TMPY-01480 | LTC4S Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Leukotriene C4 synthase, also known as LTC4 synthase, Leukotriene-C(4) synthase, and LTC4S, is a multi-pass membrane protein that belongs to the MAPEG family. LTC4S is detected in the lung, platelets, and the myelogenous... |