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ターゲット

Stearoyl-CoA Desaturase (SCD) HMG-CoA Reductase Acetyl-CoA Carboxylase RSV Fatty Acid Synthase

231

阻害剤

天然化合物

103

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T4380	Ac-CoA Synthase Inhibitor1	ACSS2 inhibitor	RSV , Fatty Acid Synthase
	Ac-CoA Synthase Inhibitor1 (ACSS2 inhibitor) is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2).		RSV , Fatty Acid Synthase
T36626	Lys-CoA
	Selective p300 histone acetyltransferase (HAT) inhibitor (IC50 = 50-500 nM). Exhibits approximately 100-fold selectivity for p300 over PCAF (IC50 = 200 μM). Inhibits p300-dependent transcription. Active in vivo. Lau et a...
T73829	Malonyl CoA
	Malonyl CoA serves as a substrate in fatty acid biosynthesis while inhibiting fatty acid oxidation. It also acts as a reversible inhibitor of mitochondrial carnitine palmitoyltransferase (CPT) 1 [1] [2].
T74197	Pimeloyl-CoA
	Pimeloyl-CoA, a precursor to biotin in Escherichia coli, serves as a key compound for researching the de novo biosynthesis pathway of biotin in this bacterium [1].
T37958	Acetyl Coenzyme A trisodium	Acetyl-CoA trisodium	OXPHOS , Endogenous Metabolite , Autophagy
	Acetyl Coenzyme A trisodium (Acetyl-CoA trisodium) is an important compound in glucose metabolism and lipid metabolism and is involved in the tricarboxylic acid cycle.		OXPHOS , Endogenous Metabolite , Autophagy
T74171	Crotonyl-CoA
	Crotonyl-CoA, an intermediate in the fermentation of butyric acid as well as in the metabolism of lysine and tryptophan, plays a crucial role in the metabolism of fatty acids and amino acids [1].
T73951	Lys-CoA TFA
	Lys-CoA TFA, a selective p300 histone acetyltransferase (HAT) inhibitor (IC 50 =50-500 nM), exhibits a specificity that exceeds 100-fold over PCAF (IC 50 =200 μM). This compound effectively suppresses transcriptional act...
T79520	HMG-CoA Reductase-IN-1
	HMG-CoA Reductase-IN-1 is an inhibitor of HMG-CoA reductase, demonstrating strong inhibitory activity on HMGR and affinity for OATP1B1, with pIC50 and pKm values of 8.54 and 1.98, respectively. It is utilized in hypercho...
T72180	Acetyl-CoA Carboxylase-IN-1
	Acetyl-CoA Carboxylase-IN-1 is a potent inhibitor of acetyl-CoA carboxylase (ACC), exhibiting an inhibition concentration (IC50) of less than 5 nM. This compound also displays antibacterial activity.
T14342	Atorvastatin lactone		HMG-CoA Reductase
	Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor.		HMG-CoA Reductase
T36827	Acetoacetyl Coenzyme A (sodium salt hydrate)	Acetoacetyl-CoA
	Acetoacetyl-coenzyme A (acetoacetyl-CoA) is a precursor to HMG-CoA in the isoprenoid pathway.[1],[2] It is reversibly converted to acetyl-CoA by acetoacetyl-CoA thiolase in the mitochondria. Acetoacetyl-CoA thiolase (T2)...
T78511	Oleoyl coenzyme A lithium	Oleoyl-CoA lithium
	Oleoyl coenzyme A (Oleoyl-CoA) lithium, a thioester derived from oleic acid and coenzyme A, functions as a metabolite in both Escherichia coli and mice [1] [2].
T32598	Lauroyl-coenzyme A	Dodecanoyl-coa,Coenzyme A, lauroyl-,Lauroyl-coa
	Lauroyl-coenzyme A can function as an acyl group carrier, acetyl-CoA. It can be used as an intermediate in lipid metabolism and is involved in lipid biosynthesis and fatty acid transport.
T37323	Succinyl-Coenzyme A sodium salt	Succinyl-CoA sodium salt,Succinyl-Coenzyme A (sodium salt),Succinyl-CoA	Endogenous Metabolite
	Succinyl-Coenzyme A sodium salt(Succinyl-CoA sodium salt) participates in the citric acid cycle, where it is converted to succinic acid.Succinyl-Coenzyme A (sodium salt) is involved in a variety of metabolic reactions in...		Endogenous Metabolite
T9214	ELOVL6-IN-1		Others
	ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities, with an IC50 value of 0.350 μM. ELOVL6-IN-1 inhibits ELOVL6 in a noncompetitive manner...		Others
T3510	Olumacostat Glasaretil		Acetyl-CoA Carboxylase
	Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.		Acetyl-CoA Carboxylase
T12490	Pitavastatin lactone		Others
	Pitavastatin lactone is a major Pitavastatin metabolite in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes.		Others
T16068	MF-438		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T13356	XEN723		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T2650	MK-8245		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T14878	CAY10566		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	CAY10566 shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells (IC50=7.9 nM or 6.8 nM). CAY10566 is a potent, orally ...		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T4515	A939572		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T6412	CVT-12012		Stearoyl-CoA Desaturase (SCD)
	CVT-12012 is an orally bioavailable inhibitor of stearoyl-CoA desaturase (SCD; IC50 = 6.1 nM in HepG2 cells).		Stearoyl-CoA Desaturase (SCD)
T20765	Atorvastatin		HMG-CoA Reductase , Autophagy
	Atorvastatin is an orally active HMG-CoA reductase inhibitor that has the ability to effectively lower blood lipids by activating liver cytochrome p450 to accelerate metabolism. Atorvastatin inhibited proliferation and i...		HMG-CoA Reductase , Autophagy
TQ0243	ND-646		Acetyl-CoA Carboxylase
	ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively)		Acetyl-CoA Carboxylase
T7163	PF-05175157		Acetyl-CoA Carboxylase
	PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively		Acetyl-CoA Carboxylase
T9722	YTX-465		Stearoyl-CoA Desaturase (SCD)
	YTX-465 is an inhibitor of both stearoyl-CoA desaturase(IC50s = 39 nM) and Ole1 (IC50s = 30.4 μM).		Stearoyl-CoA Desaturase (SCD)
T1487	Fluvastatin sodium	XU 62320 sodium,XU-62-320,Fluvastatin sodium salt	Ferroptosis , HMG-CoA Reductase , Autophagy
	Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent.		Ferroptosis , HMG-CoA Reductase , Autophagy
T6450	Clinofibrate	S-8527,Lipoclin	HMG-CoA Reductase , Autophagy
	Clinofibrate (Lipoclin)(IC50 of 0.47 mM), a lipid-lowering agent, inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR). It is utilized to control high cholesterol and triacylglyceride levels in the blood.		HMG-CoA Reductase , Autophagy
T10525	SCD1 inhibitor-4		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T10760	Ceramides Mixture		Telomerase
	Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle arrest, growth inhibition, and modulation of telomerase activ...		Telomerase
T3988	TOFA	MDL14514,RMI14514	Acetyl-CoA Carboxylase
	TOFA (MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA).		Acetyl-CoA Carboxylase
T23521	VULM 1457		Acyltransferase
	VULM 1457 is a potent ACAT inhibitor. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM1457 significantly reduces production and secretion of...		Acyltransferase
T14991	CMS-121	CMS121	Acetyl-CoA Carboxylase
	CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotect...		Acetyl-CoA Carboxylase
T1889	CP-640186	CP 640186	Acetyl-CoA Carboxylase
	CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186(CP 640186) is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.		Acetyl-CoA Carboxylase
T6994	SR12813	SR-12813,SR 12813,GW 485801	HMG-CoA Reductase , Autophagy
	SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.		HMG-CoA Reductase , Autophagy
T9102	WM-3835		Apoptosis , Histone Methyltransferase , Histone Acetyltransferase
	WM-3835 is a novel and high-specific small molecule inhibitor of Lysine Acetyltransferase 7 (KAT7, MYST2, HBO1) , able to potently suppressed OS cell proliferation and migration, and leads to apoptosis activation.
T5046	Haloxyfop	Haloxyfop Acid,(±)-Haloxyfop	Others , Acetyl-CoA Carboxylase
	(±)-Haloxyfop (Haloxyfop Acid) is a herbicide.		Others , Acetyl-CoA Carboxylase
T12092	Monacolin J	Antibiotic MB 530A,Lovastatin diol lactone	HMG-CoA Reductase , Autophagy
	Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.		HMG-CoA Reductase , Autophagy
T5427	GSK1940029	SCD inhibitor 1	Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T3622	CP-640186 hydrochloride	CP 640186 HCl	Acetyl-CoA Carboxylase
	CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stabilit...		Acetyl-CoA Carboxylase
T1869	PluriSIn 1	NSC 14613,PluriSIn #1,PluriSln 1	Apoptosis , Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	PluriSIn 1 (NSC 14613) is an inhibitor of stearoyl-CoA desaturase (SCD1), the key enzyme in oleic acid biosynthesis, revealing a unique role for lipid metabolism in hPSCs.		Apoptosis , Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T3116	Atorvastatin hemicalcium salt	Lipitor,Atorvastatin hemicalcium,Atorvastatin Calcium,CI-981,Sortis	Ferroptosis , HMG-CoA Reductase , Autophagy
	Atorvastatin hemicalcium salt (Atorvastatin Calcium), an effective HMG-CoA reductase inhibitor (IC50 = 8 nM), is utilized as a cholesterol-lowering medication.		Ferroptosis , HMG-CoA Reductase , Autophagy
T7184	Firsocostat	ND-630,NDI-010976,GS-0976	Acetyl-CoA Carboxylase
	Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)		Acetyl-CoA Carboxylase
T1676	Rosuvastatin	ZD 4522	Potassium Channel , HMG-CoA Reductase , Autophagy
	Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting...		Potassium Channel , HMG-CoA Reductase , Autophagy
T2534	Pitavastatin calcium	P-872441,nisvastatin,itavastatin,Pitavastatin hemicalcium,NK-104	Apoptosis , Mitophagy , Endogenous Metabolite , HMG-CoA Reductase , Autophagy
	Pitavastatin calcium (NK-104) is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of pitavastatin by the cyt...
T1510	Rosuvastatin calcium	ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium	Potassium Channel , HMG-CoA Reductase , Autophagy
	Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activity.		Potassium Channel , HMG-CoA Reductase , Autophagy
T9003	CVT-11127		Dehydrogenase
	CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.		Dehydrogenase
T60168	NCOA4 - 9a		Ferroptosis
	NCOA4 - 9a is a ferroptosis inhibitor.		Ferroptosis
T124030	Coatline B
	Coatline B is a useful organic compound for research related to life sciences. The catalog number is T124030 and the CAS number is 87441-89-2.

Compounds

Ac-CoA Synthase Inhibitor1

T4380

Synonym: ACSS2 inhibitor

Target: RSV, Fatty Acid Synthase

Acetyl Coenzyme A trisodium

T37958

Synonym: Acetyl-CoA trisodium

Target: OXPHOS, Endogenous Metabolite, Autophagy

HMG-CoA Reductase-IN-1

T79520

Synonym:

Target:

Acetyl-CoA Carboxylase-IN-1

Target: HMG-CoA Reductase

Acetoacetyl Coenzyme A (sodium salt hydrate)

T36827

Synonym: Acetoacetyl-CoA

Target:

Oleoyl coenzyme A lithium

T78511

Synonym: Oleoyl-CoA lithium

Target:

Lauroyl-coenzyme A

T32598

Synonym: Dodecanoyl-coa,Coenzyme A, lauroyl-,Lauroyl-coa

Target:

Succinyl-Coenzyme A sodium salt

T37323

Synonym: Succinyl-CoA sodium salt,Succinyl-Coenzyme A (sodium salt),Succinyl-CoA

Target: Endogenous Metabolite

Olumacostat Glasaretil

T3510

Synonym:

Target: Acetyl-CoA Carboxylase

Target: Dehydrogenase, Stearoyl-CoA Desaturase (SCD)

XEN723

T13356

Synonym:

Target: Dehydrogenase, Stearoyl-CoA Desaturase (SCD)

MK-8245

T2650

Synonym:

Target: Dehydrogenase, Stearoyl-CoA Desaturase (SCD)

CAY10566

T14878

Synonym:

Target: Dehydrogenase, Stearoyl-CoA Desaturase (SCD)

A939572

T4515

Synonym:

Target: Dehydrogenase, Stearoyl-CoA Desaturase (SCD)

CVT-12012

T6412

Synonym:

Target: Stearoyl-CoA Desaturase (SCD)

Atorvastatin

T20765

Synonym:

Target: HMG-CoA Reductase, Autophagy

ND-646

TQ0243

Synonym:

Target: Acetyl-CoA Carboxylase

PF-05175157

T7163

Synonym:

Target: Acetyl-CoA Carboxylase

YTX-465

T9722

Synonym:

Target: Stearoyl-CoA Desaturase (SCD)

Fluvastatin sodium

T1487

Synonym: XU 62320 sodium,XU-62-320,Fluvastatin sodium salt

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Clinofibrate

T6450

Synonym: S-8527,Lipoclin

Target: HMG-CoA Reductase, Autophagy

SCD1 inhibitor-4

T10525

Synonym:

Target: Dehydrogenase, Stearoyl-CoA Desaturase (SCD)

Synonym: MDL14514,RMI14514

Target: Acetyl-CoA Carboxylase

VULM 1457

T23521

Synonym:

Target: Acyltransferase

CMS-121

T14991

Synonym: CMS121

Target: Acetyl-CoA Carboxylase

CP-640186

T1889

Synonym: CP 640186

Target: Acetyl-CoA Carboxylase

SR12813

T6994

Synonym: SR-12813,SR 12813,GW 485801

Target: HMG-CoA Reductase, Autophagy

WM-3835

T9102

Synonym:

Target: Apoptosis, Histone Methyltransferase, Histone Acetyltransferase

Haloxyfop

T5046

Synonym: Haloxyfop Acid,(±)-Haloxyfop

Target: Others, Acetyl-CoA Carboxylase

Monacolin J

T12092

Synonym: Antibiotic MB 530A,Lovastatin diol lactone

Target: HMG-CoA Reductase, Autophagy

GSK1940029

T5427

Synonym: SCD inhibitor 1

Target: Dehydrogenase, Stearoyl-CoA Desaturase (SCD)

CP-640186 hydrochloride

T3622

Synonym: CP 640186 HCl

Target: Acetyl-CoA Carboxylase

PluriSIn 1

T1869

Synonym: NSC 14613,PluriSIn #1,PluriSln 1

Target: Apoptosis, Dehydrogenase, Stearoyl-CoA Desaturase (SCD)

Atorvastatin hemicalcium salt

T3116

Synonym: Lipitor,Atorvastatin hemicalcium,Atorvastatin Calcium,CI-981,Sortis

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Firsocostat

T7184

Synonym: ND-630,NDI-010976,GS-0976

Target: Acetyl-CoA Carboxylase

Rosuvastatin

T1676

Synonym: ZD 4522

Target: Potassium Channel, HMG-CoA Reductase, Autophagy

Pitavastatin calcium

T2534

Synonym: P-872441,nisvastatin,itavastatin,Pitavastatin hemicalcium,NK-104

Target: Apoptosis, Mitophagy, Endogenous Metabolite, HMG-CoA Reductase, Autophagy

Rosuvastatin calcium

T1510

Synonym: ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium

Target: Potassium Channel, HMG-CoA Reductase, Autophagy

CVT-11127

T9003

Synonym:

Target: Dehydrogenase

カタログ番号	製品名	別名	ターゲット
T82792	Caffeoyl-CoA
	Caffeoyl-CoA can be isolated from the leaf tissues of Gramineae, exhibiting a Km value of 1.45 μM [1].
TN1438	Beta-Amyrin acetate		Antioxidant , HMG-CoA Reductase , Epoxide Hydrolase , Antifungal
	beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, and anti-hyperlipidemic activities.
TN1733	Hesperetin 7-O-glucoside		Anti-infection , Antibacterial , HMG-CoA Reductase
	Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium. Hesperetin 7-O-glucoside shows inhibition of human HMG-CoA reductase, it also exhibits effective inh...		Anti-infection , Antibacterial , HMG-CoA Reductase
T3341	Elemicin	Elemicine,3,4,5-trimethoxyallylbenzene	Influenza Virus , 5-HT Receptor , Stearoyl-CoA Desaturase (SCD)
	Elemicin (Elemicine) is a constituent of several plant species' essential oils with anticholinergic effects in human.
T4766	3-Methylglutaric acid		Endogenous Metabolite
	Methylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase (PMID 6181239 ). Methylglutaric acid is als...		Endogenous Metabolite
TN6715	7-Ketocholesterol		Others
	7-Ketocholesterol is a metabolite of Cholesterol		Others
T1207	Lovastatin	MK-803,Mevinolin	Ferroptosis , HMG-CoA Reductase , Autophagy
	Lovastatin (MK-803) is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.		Ferroptosis , HMG-CoA Reductase , Autophagy
T0683	Mevastatin	Compactin,ML236B	Apoptosis , Antibacterial , Antibiotic , HMG-CoA Reductase , Autophagy , Lipid
	Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.
T1664	Meglutol	Dicrotalic acid,3-Hydroxy-3-methylglutaric acid	Endogenous Metabolite , HMG-CoA Reductase , Autophagy
	Meglutol (3-Hydroxy-3-methylglutaric acid) is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conve...		Endogenous Metabolite , HMG-CoA Reductase , Autophagy
T0672	Pravastatin sodium	CS-514 Sodium,CS-514 (sodium)	Ferroptosis , HMG-CoA Reductase , Autophagy
	Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.		Ferroptosis , HMG-CoA Reductase , Autophagy
T0687	Simvastatin	MK-0733,MK 733	Apoptosis , Mitophagy , Ferroptosis , HMG-CoA Reductase , Autophagy
	Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovasc...
T74203	Licoagrochalcone C
	Licoagrochalcone C, a flavonoid compound, demonstrates potent inhibitory effects on NF-κB transcription and significantly reduces LPS-induced NO production, showcasing its bioactive properties [1] [2].
TN4433	Licoarylcoumarin		cAMP , HIV Protease , Antifection
	Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE strains; it has anti-HIV activity, and it has inhibitory effe...		cAMP , HIV Protease , Antifection
T82305	Glucoarabin
	Glucoarabin, a bioactive glucosinolate, upregulates the phase II detoxification enzyme quinone reductase (NQO1) in Hepa1c1c7 cells when hydrolyzed (hGSL 9), without affecting cytochrome P450 (CYP) 1A1 activity [1].
T32742	Licoagrochalcone B
	Licoagrochalcone B is a flavonoid isolated from Patrinia villosa.
T78501	Glucoamylase
	Glucoamylase, an enzyme obtained from various sources such as plants, animals, and microorganisms, is utilized in industrial applications. It is extensively employed in starch saccharification processes and the brewing a...
T4851	Methyl acetylacetate	Methyl acetoacetate	Others , Endogenous Metabolite
	Methyl acetylacetate (Methyl acetoacetate) has been identified in the urine of patients with an inherited deficiency of propionyl-CoA carboxylase, and after isoleucine loading in the diagnosis of 2-methylacetoacetyl-CoA ...		Others , Endogenous Metabolite
TN1474	Caulilexin C		Others , Antifungal
	Caulilexin C shows inhibitory activity on human Acyl CoA: cholesterol transferase I (hACATI) and on human Acyl CoA: cholesterol transferase 2 (hACAT2) at 100 mug/ml.		Others , Antifungal
T5215	N-(3-Phenylpropionyl)glycine	Phenylpropionylglycine	Others
	N-(3-Phenylpropionyl)glycine (Phenylpropionylglycine) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors...		Others
T4734	Suberic acid	Octanedioic acid,1,8-Octanedioic acid	Others , Endogenous Metabolite
	Suberic acid (1,8-Octanedioic acid) is present in the urine of patients with fatty acid oxidation disorders. A metabolic breakdown product derived from oleic acid. Elevated levels of this unstaruated dicarboxylic acid ar...		Others , Endogenous Metabolite
T5279	Ethylmalonic acid	alpha-Carboxybutyrate,2-Ethylmalonic acid	Others , Endogenous Metabolite
	Ethylmalonic acid (alpha-Carboxybutyrate) can be found in blood, cerebrospinal fluid (CSF), and urine, as well as in human fibroblasts, prostate, and skeletal muscle tissues. Moreover, ethylmalonic acid is found to be as...		Others , Endogenous Metabolite
T14128	Adenosylcobalamin	Cobamamide,Coenzyme B12,AdoCbl	Endogenous Metabolite
	Adenosylcobalamin (AdoCbl) is a biologically active form of vitamin B12 .It is a cofactor for methylmalonyl CoA mutase. It belongs to the corrinoid group of compounds, which contain a corrin macrocycle, and is produced o...		Endogenous Metabolite
T5245	N-Isovaleroylglycine	Isovaleroylglycine,N-Isovalerylglycine	Others , Endogenous Metabolite
	N-Isovaleroylglycine (Isovaleroylglycine) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metaboli...		Others , Endogenous Metabolite
T13979	(S)-3-Hydroxybutanoic acid	L-β-Hydroxybutyric acid,(S)-β-Hydroxybutanoic acid,L-(+)-3-Hydroxybutyric acid	Endogenous Metabolite
	(S)-3-Hydroxybutanoic acid (L-(+)-3-Hydroxybutyric acid) is a normal human metabolite that has been found elevated in geriatric patients remitting from depression. (S)-3-Hydroxybutanoic acid is synthesized in the liver f...		Endogenous Metabolite
T5060	2-Oxobutanoic acid	alpha-Ketobutyric Acid,2-Oxobutyric acid,Propionylformic acid	Others , Endogenous Metabolite
	2-Oxobutanoic acid (alpha-Ketobutyric Acid) is a product of the lysis of cystathionine. It is also one of the degradation products of threonine. It can be converted into propionyl-CoA, and thus enter the citric acid cycl...		Others , Endogenous Metabolite
T4947	3-Hydroxybutyric acid	Butanoic acid	Endogenous Metabolite
	3-Hydroxybutyric acid (Butanoic acid) (or beta-hydroxybutyrate) is a ketone body. Like the other ketone bodies (acetoacetate and acetone), levels of 3-hydroxybutyrate in blood and urine are raised in ketosis. In humans, ...		Endogenous Metabolite
T5213	Acetyl phosphate(lithium potassium)	Lithium potassium acetyl phosphate,Acetylphosphoric acid	Others , Endogenous Metabolite
	Acetyl phosphate lithium potassium (Lithium potassium acetyl phosphate) is a compound involved in taurine and hypotaurine metabolism as well as pyruvate metabolism. Acetyl phosphate lithium potassiu is generated from sul...		Others , Endogenous Metabolite
T4837	Itaconic acid	methylene-butanedioicaci	Others , Endogenous Metabolite
	Itaconic acid (methylene-butanedioicaci), also known as itaconate, belongs to the class of organic compounds known as branched fatty acids. These are fatty acids containing a branched chain. Itaconic acid exists as a sol...		Others , Endogenous Metabolite
TN2111	Prunin	Naringenin 7-0-glucoside	Phosphatase , Anti-infection , Virus Protease
	Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can...		Phosphatase , Anti-infection , Virus Protease
T5291	Malonic acid	Carboxyacetic Acid,1,3-Propanedioic Acid,Propanedioic Acid	Others
	Malonic acid (propanedioic acid) is the archetypal example of a competitive inhibitor: it acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain. Malonic acid is found to be associa...		Others
T12045	(-)-Hydroxycitric acid lactone	Garcinia lactone	ATP Citrate Lyase
	(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent.(-)-Hydroxycitric acid lactone was a potent inhibitor of ATP citrate lyase, which catalyzes the extramitochondrial cleavage of citrate to oxaloac...		ATP Citrate Lyase
T4717	25-Hydroxycholesterol		Others , Endogenous Metabolite , HMG-CoA Reductase
	25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase and so it also plays a significant role in the in vivo regu...		Others , Endogenous Metabolite , HMG-CoA Reductase
T2228	Adipic acid		Others , Endogenous Metabolite
	Adipic acid is a precursor for the production of nylon.		Others , Endogenous Metabolite
T5267	N-Acetyl-L-glutamic acid	Ac-L-Glu-OH,N-Acetylglutamic acid	Others , Endogenous Metabolite
	N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu activates carbamoyl phospha...		Others , Endogenous Metabolite
T6480	D-Pantothenic acid	vitamin B5,pantothenate	Others
	D-Pantothenic acid (vitamin B5) is a water-soluble vitamin ubiquitously found in plants and animal tissues with an antioxidant property. D-Pantothenic acid is a component of coenzyme A (CoA) and a part of the vitamin B2 ...		Others
T4970	LANOSTEROL	3β-Hydroxy-8,24-lanostadiene,8,24-Lanostadien-3β-ol	Endogenous Metabolite
	Lanosterol (3β-Hydroxy-8,24-lanostadiene) is a tetracyclic triterpenoid which is the compound from which all steroids are derived.		Endogenous Metabolite
T4862	Oxaloacetic acid		Endogenous Metabolite
	Oxaloacetic acid, also known as oxosuccinic acid or oxalacetic acid, is a four-carbon dicarboxylic acid appearing as an intermediate of the citric acid cycle. In vivo, oxaloacetate (the ionized form of oxaloacetic acid) ...		Endogenous Metabolite
T4867	Erucic acid	Prifac 2990,13(Z)-Docosenoic Acid,cis-13-docosenoic acid	PI3K , Endogenous Metabolite
	Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ). Erucic acid (13(Z)-Docosenoic Acid) is broken down long-chain...		PI3K , Endogenous Metabolite
T5287	N-Acetyl-L-aspartic acid	AC-ASP-OH,N-Acetylaspartic acid	Others , Endogenous Metabolite
	N-Acetyl-L-aspartic acid (AC-ASP-OH) is a derivative of aspartic acid. It is the second most concentrated molecule in the brain after the amino acid glutamate. It is synthesized in neurons from the amino acid aspartate a...		Others , Endogenous Metabolite
T24117	Guineesine	Pipyahyine
	Guineesine is an Acyl-CoA. It acts by inhibiting cholesterol acyltransferase.
T13678	Enniatin A
	Enniatin A, a Fusarium mycotoxin, inhibits acyl-CoA: cholesterol acyltransferase (ACAT) with an IC50 of 22 μM in rat liver microsome enzyme assays.
T13199	Triacsin C	WS 1228A,FR 900190	Others
	Triacsin C, from Streptomyces aureofaciens, is a natural intracellular long-chain inhibitor of acyl-CoA synthetases (ACSL).		Others
T40383	Monensin B
	Monensin B is a polyketide compound derived from the bacterium Streptomyces cinnamonensis. Its production involves the fermentation of Streptomyces cinnamonensis, resulting in a mixture of Monensin A and Monensin B. The ...
T75626	Ganoderenic acid K
	Ganoderenic Acid K, isolated from the fruiting bodies of Ganoderma lucidum, exhibits potent inhibitory activity against HMG-CoA reductase (HMGCR), demonstrating an IC50 of 16.5 μM [1].
T78467	Trans-10-Heptadecenoic acid
	Trans-10-heptadecenoic acid, a trans-fatty acid, undergoes polymerization to form polyhydroxy-chain alkanoates via the enzymatic actions of 2,4-dienyl-CoA reductase and Delta3, Delta2-enyl-CoA isomerase. In the enzyme's ...
TN2834	27-p-Coumaroyloxyursolic acid		Others
	27-trans-p-Coumaroyloxyursolic acid and 27-cis-p-coumaroyloxyursolic acid show potent inhibitory activity in the acyl CoA cholesteryl acyl transferase (ACAT) assay.		Others
T13679	Enniatin B		ERK
	Enniatins B decreases the activation of ERK (p44/p42). Enniatin B is a Fusarium mycotoxin. Enniatin B inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 113 μM in an enzyme assay using rat liv...		ERK
T40717	6-Methyluracil	Pseudothymine
	6-Methyluracil, also known as Pseudothymine, is a metabolite derived from Uracil. It serves as an indicator for the accumulation of acetoacetyl-CoA (AACoA). Additionally, 6-Methyluracil has been observed to possess antir...
T19381	Isobutyryl-L-carnitine		5-HT Receptor
	Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.		5-HT Receptor
T13680	Enniatin B1		ERK
	Enniatin B1, a Fusarium mycotoxin, crosses the blood-brain barrier, decreases the activation of ERK (p44/p42), and inhibits moderately TNF-α-induced NF-κB activation. Furthermore, it inhibits acyl-CoA: cholesterol acyltr...		ERK
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天然物製品

Target: Antioxidant, HMG-CoA Reductase, Epoxide Hydrolase, Antifungal

Hesperetin 7-O-glucoside

TN1733

Synonym:

Target: Anti-infection, Antibacterial, HMG-CoA Reductase

Elemicin

T3341

Synonym: Elemicine,3,4,5-trimethoxyallylbenzene

Target: Influenza Virus, 5-HT Receptor, Stearoyl-CoA Desaturase (SCD)

3-Methylglutaric acid

T4766

Synonym:

Target: Endogenous Metabolite

Synonym: MK-803,Mevinolin

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Mevastatin

T0683

Synonym: Compactin,ML236B

Target: Apoptosis, Antibacterial, Antibiotic, HMG-CoA Reductase, Autophagy, Lipid

Meglutol

T1664

Synonym: Dicrotalic acid,3-Hydroxy-3-methylglutaric acid

Target: Endogenous Metabolite, HMG-CoA Reductase, Autophagy

Pravastatin sodium

T0672

Synonym: CS-514 Sodium,CS-514 (sodium)

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Simvastatin

T0687

Synonym: MK-0733,MK 733

Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy

Target: cAMP, HIV Protease, Antifection

Synonym: Methyl acetoacetate

Target: Others, Endogenous Metabolite

Caulilexin C

TN1474

Synonym:

Target: Others, Antifungal

N-(3-Phenylpropionyl)glycine

T5215

Synonym: Phenylpropionylglycine

Target: Others

Suberic acid

T4734

Synonym: Octanedioic acid,1,8-Octanedioic acid

Target: Others, Endogenous Metabolite

Ethylmalonic acid

T5279

Synonym: alpha-Carboxybutyrate,2-Ethylmalonic acid

Target: Others, Endogenous Metabolite

Adenosylcobalamin

T14128

Synonym: Cobamamide,Coenzyme B12,AdoCbl

Target: Endogenous Metabolite

N-Isovaleroylglycine

T5245

Synonym: Isovaleroylglycine,N-Isovalerylglycine

Target: Others, Endogenous Metabolite

(S)-3-Hydroxybutanoic acid

T13979

Synonym: L-β-Hydroxybutyric acid,(S)-β-Hydroxybutanoic acid,L-(+)-3-Hydroxybutyric acid

Target: Endogenous Metabolite

2-Oxobutanoic acid

T5060

Synonym: alpha-Ketobutyric Acid,2-Oxobutyric acid,Propionylformic acid

Target: Others, Endogenous Metabolite

3-Hydroxybutyric acid

T4947

Synonym: Butanoic acid

Target: Endogenous Metabolite

Acetyl phosphate(lithium potassium)

T5213

Synonym: Lithium potassium acetyl phosphate,Acetylphosphoric acid

Target: Others, Endogenous Metabolite

Itaconic acid

T4837

Synonym: methylene-butanedioicaci

Target: Others, Endogenous Metabolite

Prunin

TN2111

Synonym: Naringenin 7-0-glucoside

Target: Phosphatase, Anti-infection, Virus Protease

Malonic acid

T5291

Synonym: Carboxyacetic Acid,1,3-Propanedioic Acid,Propanedioic Acid

Target: Others

(-)-Hydroxycitric acid lactone

T12045

Synonym: Garcinia lactone

Target: ATP Citrate Lyase

25-Hydroxycholesterol

T4717

Synonym:

Target: Others, Endogenous Metabolite, HMG-CoA Reductase

Adipic acid

T2228

Synonym:

Target: Others, Endogenous Metabolite

N-Acetyl-L-glutamic acid

T5267

Synonym: Ac-L-Glu-OH,N-Acetylglutamic acid

Target: Others, Endogenous Metabolite

D-Pantothenic acid

T6480

Synonym: vitamin B5,pantothenate

Target: Others

LANOSTEROL

T4970

Synonym: 3β-Hydroxy-8,24-lanostadiene,8,24-Lanostadien-3β-ol

Target: Endogenous Metabolite

Oxaloacetic acid

T4862

Synonym:

Target: Endogenous Metabolite

Erucic acid

T4867

Synonym: Prifac 2990,13(Z)-Docosenoic Acid,cis-13-docosenoic acid

Target: PI3K, Endogenous Metabolite

N-Acetyl-L-aspartic acid

T5287

Synonym: AC-ASP-OH,N-Acetylaspartic acid

Target: Others, Endogenous Metabolite

Synonym: WS 1228A,FR 900190

trans-10-Heptadecenoic acid

T78467

Synonym:

Target:

27-p-Coumaroyloxyursolic acid

Synonym: Pseudothymine

Target:

Isobutyryl-L-carnitine

T19381

Synonym:

Target: 5-HT Receptor

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-05357	GCDH Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	GCDH Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells with His tag. The predicted molecular weight is 44.9 kDa. Accession number: Q92947-1
TMPH-00405	Acyl-CoA dehydrogenase Protein, Clostridium acetobutylicum, Recombinant (His & Myc)	Clostridium acetobutylicum	E. coli
	Acyl-CoA dehydrogenase Protein, Clostridium acetobutylicum, Recombinant (His & Myc) is expressed in E. coli.
TMPY-02481	ACOX1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, ...
TMPH-03409	4CL Protein, Rhodobacter capsulatus, Recombinant (His)	Rhodobacter capsulatus	E. coli
	Converts p-coumaric acid into p-coumaryl CoA. This is necessary for the activation of the photoactive yellow protein (PYP) chromophore.
TMPH-00875	ACAT1 Protein, Human, Recombinant (His)	Human	E. coli
	This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleava...
TMPJ-01302	ACAT2 Protein, Human, Recombinant (His)	Human	E. coli
	ACAT2 is a cytoplasmic enzyme which belongs to the thiolase family. ACAT2 takes part in lipid metabolism, lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. It is responsible for the synthesi...
TMPH-03433	ACB1 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	Yeast
	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters.
TMPY-04813	ACAT2 Protein, Rat, Recombinant (His)	Rat	E. coli
	Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in various tissues. In mammals, two ACAT genes (ACAT1 and ACAT2) have been identified. Together, these two e...
TMPH-00569	AtoD Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	atoD Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli.
TMPH-00330	Acetyl-CoA carboxylase Protein, Candida albicans, Recombinant (His)	Candida albicans	E. coli
	Acetyl-CoA carboxylase Protein, Candida albicans, Recombinant (His) is expressed in E. coli with N-terminal 10xHis tag. The predicted molecular weight is 67.3 kDa. Accession number: A0A1D8PRR7
TMPH-00339	Acetyl-CoA carboxylase Protein, Candida glabrata, Recombinant (His)	Candida glabrata	E. coli
	Acetyl-CoA carboxylase Protein, Candida glabrata, Recombinant (His) is expressed in E. coli with N-terminal 10xHis tag. The predicted molecular weight is 67.2 kDa. Accession number: A0A0W0CTK3
TMPH-02764	ACSL4 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	ACSL4 Protein, Mouse, Recombinant (His) is expressed in E. coli.
TMPY-03464	ECH1 Protein, Human, Recombinant (His)	Human	E. coli
	ECH1 is a member of the hydratase/isomerase superfamily. ECH1 shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. ECH1 con...
TMPH-02488	ACSS2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate but can also utilize propionate with a much lower affinity.
TMPY-01345	ACBD6 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Human acyl-coenzyme A binding domain-containing member 6 (ACBD6) is a modular protein that carries an acyl-CoA binding domain at its N terminus and two ankyrin motifs at its C terminus. In mammals, there are six members ...
TMPH-00876	ACSS1 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation un...
TMPH-00877	ACSS1 Protein, Human, Recombinant (His)	Human	Yeast
	Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation un...
TMPY-05066	IVD Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	IVD (Isovaleryl-CoA Dehydrogenase) is a Protein Coding gene. IVD is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. IVD plays an essential role in processing proteins obtained from the ...
TMPH-02825	ACOX1 Protein, Mouse, Recombinant (Myc)	Mouse	E. coli
	Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. First enzyme of the fatty acid beta-oxidation pathway.; Shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing ch...
TMPY-00412	ACAA1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	ACAA1 Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells with His tag. The predicted molecular weight is 43.8 kDa. Accession number: A0A024R2M6
TMPY-01427	AACS Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Acetoacetyl-CoA Synthetase (AACS) is a novel cytosolic ketone body (acetoacetate)-specific ligase. The AACS in adipose tissue plays an important role in utilizing ketone body for the fatty acid-synthesis during adipose t...
TMPH-02642	ECHS1 Protein, Mouse, Recombinant (C225S, HA & His)	Mouse	Baculovirus
	Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. Has high substrate specificity for crotonyl-CoA and moderate specificity for acryloyl-CoA, 3-methylcr...
TMPH-03759	ECHS1 Protein, Mouse, Recombinant (HA & His)	Mouse	E. coli
	Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. Has high substrate specificity for crotonyl-CoA and moderate specificity for acryloyl-CoA, 3-methylcr...
TMPH-00406	CtfB Protein, Clostridium acetobutylicum, Recombinant (His & Myc)	Clostridium acetobutylicum	E. coli
	ctfB Protein, Clostridium acetobutylicum, Recombinant (His & Myc) is expressed in E. coli.
TMPY-03417	ACBD7 Protein, Human, Recombinant (His)	Human	E. coli
	ACBD7, acyl-CoA-binding domain-containing protein 7, is a small (1 Kd) protein that contains 1 ACB (acyl-CoA-binding) domain. The ACB domain consists of four alpha-helices arranged in a bowl shape with a highly exposed ...
TMPY-01140	ACOT13/THEM2 Protein, Human, Recombinant (His)	Human	E. coli
	The metabolites of fatty acyl-Coenzyme A (CoA) and metabolic enzymes contribute to lipid biosynthesis, signal transduction, and gene transcription. Members of the acyl-CoA thioesterase (Acot) gene family hydrolyze fatty ...
TMPY-00488	COASY Protein, Human, Recombinant (His)	Human	E. coli
	COASY Protein, Human, Recombinant (His) is expressed in E. coli with His tag. The predicted molecular weight is 32.5 kDa. Accession number: Q13057-1
TMPJ-00834	ACADM Protein, Human, Recombinant (His)	Human	E. coli
	Medium-Chain Specific Acyl-CoA Dehydrogenase (ACADM) is a mitochondrial fatty acid beta-oxidation that belongs to the acyl-CoA dehydrogenase family. ACADM is a homotetramer enzyme that catalyzes the initial step of the m...
TMPH-00890	DBI Protein, Human, Recombinant (aa 2-104, His)	Human	E. coli
	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site lo...
TMPY-03109	PHYH Protein, Human, Recombinant	Human	E. coli
	PHYH belongs to the family of iron(II)-dependent oxygenases, which typically incorporate one atom of dioxygen into the substrate and one atom into the succinate carboxylate group. PHYH is expressed in liver, kidney, and ...
TMPH-03235	DBI Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site lo...
TMPH-02492	DBI Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site lo...
TMPH-03432	ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His)	Saccharomyces cerevisiae	E. coli
	Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nucle...
TMPH-03431	ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His)	Saccharomyces cerevisiae	E. coli
	Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nucle...
TMPJ-00460	MECR Protein, Human, Recombinant (His)	Human	Human Cells
	Trans-2-Enoyl-CoA Reductase Mitochondrial (MECR) belongs to the zinc-containing alcohol dehydrogenase family. MECR localizes to the mitochondrion. It is highly expressed in skeletal and heart muscle and expressed at lowe...
TMPY-03991	DBI Protein, Human, Recombinant (His)	Human	E. coli
	The diazepam binding inhibitor (DBI), alternatively known as the acyl-CoA binding protein (ACBP), is involved in multiple biological actions. The polypeptide binds to the peripheral, or mitochondrial, benzodiazepine rece...
TMPY-01101	Coagulation factor X/F10 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the...
TMPY-02215	Coagulation factor IX/F9 Protein, Human, Recombinant (His)	Human	HEK293
	Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, on...
TMPY-01104	Coagulation factor XI/F11 Protein, Human, Recombinant (His)	Human	HEK293
	Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p...
TMPY-02185	Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)	Human	HEK293
	Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ...
TMPK-00993	Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His)	Canine	HEK293
	Tissue factor (also named Coagulation Factor III) is a cell surface glycoprotein responsible for initiating the extrinsic pathway of coagulation.Tissue factor is the primary cellular initiator of blood coagulation via in...
TMPJ-00301	Coagulation Factor X Protein, Human, Recombinant (hFc)	Human	Human Cells
	F10, also known as Coagulation factor X, belongs to the peptidase S1 family that is synthesized as a 488 amino acid (aa) with a signal peptide and a pro region (residues 1‑40). Both the intrinsic and extrinsic pathways a...
TMPY-02014	Coagulation factor VII/F7 Protein, Human, Recombinant (His)	Human	HEK293
	Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is...
TMPH-03106	Coagulation factor XII Protein, Pig, Recombinant (His)	Sus scrofa (Pig)	E. coli
	Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, whic...
TMPY-05355	Coagulation factor IX/F9 Protein, Human, Recombinant (hFc)	Human	HEK293
	Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, on...
TMPK-01271	Coagulation factor XI Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a co...
TMPH-03722	Coagulase/fibrinolysin Protein, Yersinia pestis, Recombinant (His & Myc)	Yersinia pestis	E. coli
	Seems to play an essential role in plague transmission by mediating flea blockage in a temperature-dependent fashion. Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lowe...
TMPH-01107	Coagulation factor V Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Coagulation factor V Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-03268	Coagulation factor XI Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	Coagulation factor XI Protein, Rat, Recombinant (His & Myc) is expressed in E. coli.
TMPY-06714	Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, on...
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GCDH Protein, Human, Recombinant (His)

TMPY-05357

Species: Human

Expression System: Baculovirus-Insect Cells

Acyl-CoA dehydrogenase Protein, Clostridium acetobutylicum, Recombinant (His & Myc)

TMPH-00405

Species: Clostridium acetobutylicum

Expression System: E. coli

ACOX1 Protein, Human, Recombinant (His)

TMPY-02481

Species: Human

Expression System: Baculovirus-Insect Cells

4CL Protein, Rhodobacter capsulatus, Recombinant (His)

TMPH-03409

Species: Rhodobacter capsulatus

Expression System: E. coli

ACAT1 Protein, Human, Recombinant (His)

TMPH-00875

Species: Human

Expression System: E. coli

ACAT2 Protein, Human, Recombinant (His)

TMPJ-01302

Species: Human

Expression System: E. coli

ACB1 Protein, S. cerevisiae, Recombinant (His)

TMPH-03433

Species: Saccharomyces cerevisiae

Expression System: Yeast

ACAT2 Protein, Rat, Recombinant (His)

TMPY-04813

Species: Rat

Expression System: E. coli

atoD Protein, E. coli, Recombinant (His & Myc)

TMPH-00569

Species: E. coli

Expression System: E. coli

Acetyl-CoA carboxylase Protein, Candida albicans, Recombinant (His)

TMPH-00330

Species: Candida albicans

Expression System: E. coli

Acetyl-CoA carboxylase Protein, Candida glabrata, Recombinant (His)

TMPH-00339

Species: Candida glabrata

Expression System: E. coli

ACSL4 Protein, Mouse, Recombinant (His)

TMPH-02764

Species: Mouse

Expression System: E. coli

ECH1 Protein, Human, Recombinant (His)

TMPY-03464

Species: Human

Expression System: E. coli

ACSS2 Protein, Mouse, Recombinant (His)

TMPH-02488

Species: Mouse

Expression System: E. coli

ACBD6 Protein, Human, Recombinant (His)

TMPY-01345

Species: Human

Expression System: Baculovirus-Insect Cells

ACSS1 Protein, Human, Recombinant (E. coli, His)

TMPH-00876

Species: Human

Expression System: E. coli

ACSS1 Protein, Human, Recombinant (His)

TMPH-00877

Species: Human

Expression System: Yeast

IVD Protein, Mouse, Recombinant (His)

TMPY-05066

Species: Mouse

Expression System: Baculovirus-Insect Cells

ACOX1 Protein, Mouse, Recombinant (Myc)

TMPH-02825

Species: Mouse

Expression System: E. coli

ACAA1 Protein, Human, Recombinant (His)

TMPY-00412

Species: Human

Expression System: Baculovirus-Insect Cells

AACS Protein, Human, Recombinant (His)

TMPY-01427

Species: Human

Expression System: Baculovirus-Insect Cells

ECHS1 Protein, Mouse, Recombinant (C225S, HA & His)

TMPH-02642

Species: Mouse

Expression System: Baculovirus

ECHS1 Protein, Mouse, Recombinant (HA & His)

TMPH-03759

Species: Mouse

Expression System: E. coli

ctfB Protein, Clostridium acetobutylicum, Recombinant (His & Myc)

TMPH-00406

Species: Clostridium acetobutylicum

Expression System: E. coli

ACBD7 Protein, Human, Recombinant (His)

TMPY-03417

Species: Human

Expression System: E. coli

ACOT13/THEM2 Protein, Human, Recombinant (His)

TMPY-01140

Species: Human

Expression System: E. coli

COASY Protein, Human, Recombinant (His)

TMPY-00488

Species: Human

Expression System: E. coli

ACADM Protein, Human, Recombinant (His)

TMPJ-00834

Species: Human

Expression System: E. coli

DBI Protein, Human, Recombinant (aa 2-104, His)

TMPH-00890

Species: Human

Expression System: E. coli

PHYH Protein, Human, Recombinant

TMPY-03109

Species: Human

Expression System: E. coli

DBI Protein, Rat, Recombinant (His & Myc)

TMPH-03235

Species: Rat

Expression System: E. coli

DBI Protein, Mouse, Recombinant (His & Myc)

TMPH-02492

Species: Mouse

Expression System: E. coli

ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His)

TMPH-03432

Species: Saccharomyces cerevisiae

Expression System: E. coli

ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His)

TMPH-03431

Species: Saccharomyces cerevisiae

Expression System: E. coli

MECR Protein, Human, Recombinant (His)

TMPJ-00460

Species: Human

Expression System: Human Cells

DBI Protein, Human, Recombinant (His)

TMPY-03991

Species: Human

Expression System: E. coli

Coagulation factor X/F10 Protein, Human, Recombinant (His)

TMPY-01101

Species: Human

Expression System: Baculovirus-Insect Cells

Coagulation factor IX/F9 Protein, Human, Recombinant (His)

TMPY-02215

Species: Human

Expression System: HEK293

Coagulation factor XI/F11 Protein, Human, Recombinant (His)

TMPY-01104

Species: Human

Expression System: HEK293

Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)

TMPY-02185

Species: Human

Expression System: HEK293

Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His)

TMPK-00993

Species: Canine

Expression System: HEK293

Coagulation Factor X Protein, Human, Recombinant (hFc)

TMPJ-00301

Species: Human

Expression System: Human Cells

Coagulation factor VII/F7 Protein, Human, Recombinant (His)

TMPY-02014

Species: Human

Expression System: HEK293

Coagulation factor XII Protein, Pig, Recombinant (His)

TMPH-03106

Species: Sus scrofa (Pig)

Expression System: E. coli

Coagulation factor IX/F9 Protein, Human, Recombinant (hFc)

TMPY-05355

Species: Human

Expression System: HEK293

Coagulation factor XI Protein, Cynomolgus, Recombinant (His)

TMPK-01271

Species: Cynomolgus

Expression System: HEK293

Coagulase/fibrinolysin Protein, Yersinia pestis, Recombinant (His & Myc)

TMPH-03722

Species: Yersinia pestis

Expression System: E. coli

Coagulation factor V Protein, Human, Recombinant (His & SUMO)

TMPH-01107

Species: Human

Expression System: E. coli

Coagulation factor XI Protein, Rat, Recombinant (His & Myc)

TMPH-03268

Species: Rat

Expression System: E. coli

Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His)

TMPY-06714

Species: Cynomolgus

Expression System: HEK293

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カタログ番号	製品名
L7500	Coagulation and Anticoagulation Compound Library	144 compounds
	A unique collection of 144 procoagulation and anticoagulation related compounds for high throughput screening (HTS) and high content screening (HCS);
L2510	Lipid Metabolism Compound Library	492 compounds
	A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).

ライブラリー

Coagulation and Anticoagulation Compound Library

L7500

Compounds: 144

Lipid Metabolism Compound Library

L2510

Compounds: 492