| T8205 |
Norwogonin
|
5,7,8-Trihydroxyflavone |
Virus Protease
|
|
Norwogonin (5,7,8-Trihydroxyflavone), isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml). |
| TN3091 |
5,7-Diacetoxy-8-methoxyflavone
|
ZINC77031696 |
PDE
|
|
5,7-Diacetoxy-8-methoxyflavone is derived from the roots of Scutellaria baicalensis and inhibits cAMP phosphodiesterase. |
| T3932 |
Viscidulin I
|
|
Others
|
|
Viscidulin I is found in Scutellaria baicalensis and is a natural product. |
| TN2436 |
4-methyl-6-phenyl-2H-pyranone
|
4-methyl-6-phenyl-2H-pyranone |
Mitochondrial Metabolism
|
|
4-methyl-6-phenyl-2H-pyranone is derived from Scutellaria baicalensis Georgi and improves mitochondrial functionality to protect astrocytes against hydrogen peroxide-induced toxicity. |
| T2775 |
Baicalin
|
Baicalein 7-O-β-D-glucuronide |
NF-κB
,
HIV Protease
,
GABA Receptor
,
Autophagy
|
|
Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV properties. |
| TN3176 |
6-Methoxynaringenin
|
|
NO Synthase
|
|
6-Methoxynaringenin is an aerial part of Scutellaria barbata D. Don (Lamiaceae) and inhibits NO production efficiently with an IC50 value of 25.8 μM. |
| TN2302 |
Viscidulin III
|
Ganhuangenin |
Glucosidase
|
|
Viscidulin III (Ganhuangenin) is present in Scutellaria baicalensis and acts as an α-glucosidase inhibitor. |
| T2789 |
Scutellarin
|
Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide |
Akt
,
HIV Protease
,
STAT
|
|
Scutellarin (Scutellarein-7-glucuronide), an active flavone isolated from Scutellaria baicalensis, can inhibit RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, and down-regulate the STAT3/Girdin/Akt signal... |
| TN3176L |
(2R)-6-Methoxynaringenin
|
|
|
|
(2R)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one is one of the potentially active components in Scutellaria baicalensis. |
| TN1040 |
Skullcapflavone II
|
|
COX
,
Antibacterial
,
TGF-beta/Smad
|
|
Skullcapflavone II is a flavonoid derived from Scutellaria baicalensis, a widely used herbal medicine in anti-inflammatory and anticancer therapy. Skullcapflavone II may have therapeutic potential for the treatment of al... |
| TN2353 |
8-Hydroxyapigenin
|
Isoscutellarein |
Antioxidant
,
Influenza Virus
|
|
8-Hydroxyapigenin (Isoscutellarein) is a brassinaceous compound derived from the plant Scutellaria baicalensis with anti-inflammatory, antioxidant and anti-influenza virus activity. |
| TN3848 |
Dihydrobaicalein
|
|
PLK
|
|
Dihydrobaicalein is a natural product from Scutellaria baicalensis, a PLK1 inhibitor (IC50:6.3 μM).Dihydrobaicalein inhibits VRK2 and PLK2. |
| TN7053 |
3',4',7-Trimethoxyquercetin
|
3,5-Dihydroxy-7,3',4'-trimethoxyflavone,Quercetin 3′,4′,7-trimethyl ether |
Others
|
|
3',4',7-Trimethoxyquercetin (3,5-Dihydroxy-7,3',4'-trimethoxyflavone) is a polymethoxyquercetin isolated from Scutellaria baicalensis with antioxidant activity. |
| TN7040 |
Taxifolin 7-O-β-D-glucoside
|
Taxifolin 7-Glucoside |
Others
|
|
Taxifolin 7-O-β-D-glucoside is a flavonoid mainly found in endosperm and involved in defense against pathogens and UV damage. |
| T5779 |
MOSLOFLAVONE
|
|
IL Receptor
,
Virus Protease
,
TNF
,
Antibacterial
|
|
MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM, respectively. |
| T3891 |
Oroxylin A-7-O-glucuronide
|
Oroxylin A Glucoronide,Oroxyloside,Oroxylin A 7-O-beta-D-glucuronide |
Others
|
|
Oroxylin A-7-O-glucuronide (Oroxylin A Glucoronide) and wogonoside should also be served as the chemical markers together with baicalin for the quality control of herbs and proprietary traditional Chinese medicine (PTCM)... |
| TN2195 |
Scutebarbatine Y
|
|
Others
|
|
Scutebarbatine Y is a natural product from Scutellaria barbata. |
| TN3268 |
8,8''-Bibaicalein
|
|
Others
|
|
8,8''-Bibaicalein is a natural product from Scutellaria baicalensis. |
| T83303 |
5,7,8-Trihydroxy-6-methoxy flavone-7-O-glucuronideb
|
|
|
|
5,7,8-Trihydroxy-6-methoxyflavone-7-O-glucuronide is a naturally occurring compound extractable from Scutellaria baicalensis Georgi [1]. |
| T82558 |
Dihydrobaicalin
|
|
|
|
Dihydrobaicalin, a flavonoid glycoside, is isolated from the American skullcap (Scutellaria lateriflora L.) [1]. |
| T81597 |
Oroxylin A 7-O-β-D-glucuronide methyl ester
|
|
|
|
Oroxylin A 7-O-β-D-glucuronide methyl ester, a natural product, can be isolated from the roots of Scutellaria baicalensis Georgi [1]. |
| T83306 |
5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside
|
|
|
|
5,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside, a natural compound, is isolatable from the root of Scutellaria repens Buch.-Ham. ex D. Don [1]. |
| TN2196 |
Scutebarbatine Z
|
|
Others
|
|
Scutebarbatine Z is a natural product from Scutellaria barbata. |
| TN5573 |
Scutebata G
|
|
|
|
Scutebata G is a natural product of Scutellaria, Lamiaceae. The catalog number is TN5573 and the CAS number is 1207181-63-2. Scutebata G can be used as a reference standard. |
| TN3480 |
Baicalein 7-O-beta-D-ethylglucuronide
|
|
Others
|
|
Baicalein 7-O-beta-D-ethylglucuronide is a natural product from Scutellaria baicalensis Georgi. |
| T31205 |
Darendoside B
|
Deacyl martynoside |
|
|
Darendoside B is a new phenethyl alcohol glycosides, were isolated from the methanolic extract of the aerial parts of Scutellaria orientalis subsp. |
| TN2689 |
2',3,5,6',7-Pentahydroxyflavanone
|
3,5,7,2',6'-Pentahydroxyflavanone |
NO Synthase
|
|
2',3,5,6',7-Pentahydroxyflavanone (3,5,7,2',6'-Pentahydroxyflavanone) is a natural product isolated from the roots of Scutellaria baicalensis. |
| TN4979 |
Scutellaric acid
|
|
Others
|
|
Scutellaric acid is a natural product of Scutellaria, Lamiaceae. The catalog number is TN4979 and the CAS number is 102919-76-6. Scutellaric acid can be used as a reference standard. |
| TN2722 |
2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one
|
|
Others
|
|
2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one is a natural product of Scutellaria, Lamiaceae. The catalog number is TN2722 and the CAS number is 1167483-18-2. 2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4... |
| TN3227 |
7-Hydroxy-2',5,8-trimethoxyflavanone
|
|
Others
|
|
7-Hydroxy-2',5,8-trimethoxyflavanone is a natural product of Scutellaria, Lamiaceae. The catalog number is TN3227 and the CAS number is 100079-34-3. 7-Hydroxy-2',5,8-trimethoxyflavanone can be used as a reference standar... |
| TN2745 |
2',7-Dihydroxy-5,8-dimethoxyflavanone
|
|
Others
|
|
2',7-Dihydroxy-5,8-dimethoxyflavanone is a natural product of Scutellaria, Lamiaceae. The catalog number is TN2745 and the CAS number is 1351338-14-1. 2',7-Dihydroxy-5,8-dimethoxyflavanone can be used as a reference stan... |
| TN2713 |
2',4'-Dihydroxy-2,3',6'-trimethoxychalcone
|
|
Others
|
|
2',4'-Dihydroxy-2,3',6'-trimethoxychalcone is a natural product of Scutellaria, Lamiaceae. The catalog number is TN2713 and the CAS number is 100079-39-8. 2',4'-Dihydroxy-2,3',6'-trimethoxychalcone can be used as a refer... |
| T2858 |
Baicalein
|
5,6,7-Trihydroxyflavone |
Ferroptosis
,
Influenza Virus
,
ROS
,
Xanthine Oxidase
|
|
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor. |
| TN1427 |
Baicalin methyl ester
|
|
Anti-infection
|
|
Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT). |
| T7051 |
5,6,7-TRIMETHOXYFLAVONE
|
Baicalein Trimethyl Ether |
p38 MAPK
|
|
5,6,7-Trimethoxyflavone, a natural product extracted from Japanese Callicarpa, acts as a p38-α MAPK inhibitor and exhibits anti-inflammatory properties. |
| T5S0788 |
Oroxin A
|
Baicalein 7-O-glucoside |
PPAR
|
|
Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects. |
| T2S0842 |
Scutellarin methyl ester
|
Scutellarin methylester |
Others
|
|
Scutellarin methyl ester has the effect of improving sleep, such as prolonging sleep time, increasing the incidence of sleep, shortening sleep latency, which also helps to delay aging process. |
| T3318 |
Wogonoside
|
Glychionide B,Wogonin 7-O-glucuronide,Oroxindin |
GABA Receptor
,
Autophagy
|
|
Wogonoside (Wogonin 7-O-glucuronide) acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor. |
| T2S0843 |
Negletein
|
7-O-Methylbaicalein,Baicalein-7-methylether |
IL Receptor
,
TNF
,
NOS
,
Interleukin
|
|
1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n... |
| TN2011 |
Ombuoside
|
Ombuin-3beta-rutinoside |
Antibacterial
|
|
Ombuoside (Ombuin-3beta-rutinoside) has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays.Ombuoside is a glycoside ombuoside isolated from Gynostemma penta... |
| TN1487 |
Chrysin 6-C-arabinoside 8-C-glucoside
|
|
Others
|
|
Chrysin 6-C-arabinoside 8-C-glucoside and chrysin-6-C-glucosyl-8-C-arabinoside are α±-glucosidase inhibitors, α±-glucosidase inhibitors are widely used in the treatment of type 2 diabetes. |
| T3319 |
Scutellarein
|
4',5,6,7-Tetrahydroxyflavone,6-Hydroxyapigenin |
SARS-CoV
,
Src
,
Autophagy
|
|
Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity. |
| T2S0850 |
Malic acid
|
E 296,2-Hydroxysuccinic acid,Hydroxybutanedioic acid,FDA 2018,Deoxytetraric acid,Pomalus acid |
Others
,
Endogenous Metabolite
|
|
1. Malic acid (Pomalus acid) did reduce populations of L. monocytogenes on poultry. 2. Malic acid supplementation may be useful for conservative treatment of calcium renal stone disease by virtue of its capacity to induc... |
| T2933 |
Wogonin
|
Vogonin |
Apoptosis
,
Wnt/beta-catenin
,
CDK
,
Autophagy
|
|
Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties. |
| TJS0851 |
Plantagoside
|
|
Others
|
|
Plantagoside is a specific non-competitive inhibitor for jack bean alpha-mannosidase (IC50: 5 μM). It also is a potent inhibitor of the Maillard reaction. |
| T3780 |
Oroxin B
|
Hypocretin-2 |
Apoptosis
,
PTEN
,
Antioxidant
,
PI3K
,
Autophagy
|
|
Oroxin B (Hypocretin-2) has antioxidant activity. |
| T8296 |
5,7,4'-Trimethoxyflavone
|
4',5,7-Trimethoxyflavone |
Apoptosis
,
PARP
,
Caspase
|
|
5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand. |
| TN1271 |
Scutellarein tetramethyl ether
|
4',5,6,7-Tetramethoxyflavone |
PAFR
|
|
Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is extracted from Siam weeds and exhibits anti-inflammatory activity through NF-κB pathway. |
| TN5238 |
Viscidulin II
|
|
IL Receptor
,
TNF
|
|
Viscidulin II can be potential therapeutic agents against P. acnes-induced skin inflammation, it can significantly suppress P. acnes-induced IL-8 and IL-1β production in THP-1 cells, concomitant intradermal injection of ... |
| TN5033 |
Skullcapflavone I
|
|
IL Receptor
,
Caspase
,
Prostaglandin Receptor
|
|
Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dep... |
