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Search Results for " oncogenic "

ターゲット

66

阻害剤

5

天然化合物

42

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T21302 UNC569 UNC 569 TAM Receptor
UNC569 (UNC 569) is a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. It is also a selective uric acid re-absorption inhibitor. UNC569 could normalize the amoun...
T6626 PF-3758309 PF-309,PF-03758309,PF 3758309 Apoptosis , PAK
PF-3758309 (PF-03758309) (IC50=1.3 nM), a pyrrolopyrazole inhibitor of PAK4, has effective ATP-competition.
T4230 PF-3758309 hydrochloride PF-03758309 hydrochloride Apoptosis , PAK
PF-3758309 hydrochloride (PF-03758309 hydrochloride) , is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PF-3758309 hyd...
T6556 K-Ras(G12C) inhibitor 9 Raf
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).
T2275 YK-4-279 Apoptosis , DNA/RNA Synthesis
YK 4-279, an inhibitor of RNA Helicase A (RHA), binds to the oncogenic transciption factor EWS-FLI1.
T7326 6H05 (TFA) 6H05 TFA,6H05 trifluoroacetate Ras
6H05 TFA (6H05 trifluoroacetate) is a selective, and allosteric oncogenic mutant K-Ras(G12C) inhibitor.
T6555 K-Ras(G12C) inhibitor 12 Apoptosis , Raf , Ras
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).
T37422L Ras Inhibitory Peptide acetate Ras Inhibitory Peptide acetate(159088-48-9 Free base) Ras
Ras Inhibitory Peptide acetate is a peptide involved in the Ras-dependent signaling pathway that plays an important role in human cancers initiated by oncogenic receptors.
T60031 NRX-1933
NRX-1933 is a molecular glue and enhances the interaction between an oncogenic transcription factor, β-Catenin, and its cognate E3 ligase, SCFβ-TrCP.
T9589 SI-113 SGK
SI-113 is a potent and selective inhibitor of SGK1, a serine/threonine protein kinase, that modulates several oncogenic signaling cascades.
T69980 XMU-MP-2 BTK , Protease
XMU-MP-2 is a potent and selective protease inhibitor with anticancer activity that inhibits the growth of oncogenic BRK-driven tumors in a mouse xenograft model.
T1744 BIX02188 Apoptosis , MEK
BIX02188 is a selective and potent MEK5 inhibitor that inhibits MEK5-induced apoptosis in cells expressing the oncogenic mutant FLT3-ITD.
T6284 Onalespib AT13387,Onalespib (AT13387) HSP
Onalespib (AT13387) is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Onalespib selectively binds to Hsp90, thereby inhibiting its chap...
T8402 Regorafenib Hydrochloride BAY73-4506 hydrochloride Raf , VEGFR , c-RET , PDGFR , Autophagy
Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity
T20168 Aurothiomalate sodium Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate Others , PKC
Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate ...
T9072 Tuxobertinib BDTX-189 EGFR , HER , BTK , RIP kinase
Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations(KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively). BDTX-189 exhibits anticancer activ...
T3646 RSL3 RSL3 1S,1S,3R-RSL3 Ferroptosis , GPX , Glutathione Peroxidase
RSL3 (RSL3 1S) is an inhibitor of GPX4, and inhibits system xc- that blocks GSH synthesis (IC50=100 nM). RSL3 is a VDAC-independent activator of iron death that is selective for tumor cells carrying oncogenic RAS.
T21981 Phthalazinone pyrazole Aurora Kinase
Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.
TQ0048 BI-882370 Raf
BI-882370 is a specific RAF kinase inhibitor. BI-882370 inhibits the oncogenic BRAFV600E-mutant, the WT BRAF and CRAF kinases (IC50s: 0.4, 0.8 and 0.6 nM). BI-882370 also inhibits SRC family kinases.
T8488 GMB-475 Bcr-Abl
GMB-475 is a BCR-ABL1 tyrosine kinase degrader based on PROTAC, overcoming BCR-ABL1-dependent drug resistance. GMB-475 targets BCR-ABL1 protein and recruits the E3 ligase Von Hippel Lindau (VHL).resulting in ubiquitinati...
T6017 Linsitinib OSI-906 IGF-1R
OSI-906 (Linsitinib (OSI-906)) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Linsitinib selectively inhibits IGF-1R, whic...
T63049 CHD1Li 6.11 Others
CHD1Li 6.11 is a potent inhibitor of oncogenic CHD1L, acting on the cat-CHD1L recombinant protein (IC50: 3.3 μM). CHD1Li 6.11 is an orally active antitumour agent that significantly reduces the tumour volume of CRC xenog...
T68405 KW-2450 free base IGF-1R
KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free ...
T70476 SML-10-70-1
SML-10-70-1 is a Novel Active Site Inhibitor of Oncogenic K-Ras G12C.
T33219 MB725 MB 725,MB-725
MB725 is a strong and selective inducer of viability reduction in several cancer cell lines containing the oncogenic p53-Y220C mutation.
T71635 Murayaquinone
Murayaquinone is a hepatitis C virus proteinase inhibitor and small molecule antagonist of the oncogenic Tcf/β-catenin protein complex.
T1931 6H05 K-Ras inhibitor Raf , Ras
6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).
T34670 SNIPER(ABL)-38
SNIPER(ABL)-38 is a specific and nongenetic IAP-dependent protein eraser (SNIPER) which acts as a protein degradation inducer of oncogenic BCR-ABL protein.
T32419 KRAS4b-PDEδ stabilizer C19
KRAS4b-PDEδ stabilizer C19 is a stabilizer of the KRAS4b-PDEδ complex which decreases the proliferation of colorectal cancer cells, and increases apoptosis via decreased activation of oncogenic KRAS4b signaling.
T69264 Aristeromycin diphosphate
Aristeromycin diphosphate is an inhibitor of S-adenosylhomocysteine hydrolase (AHCY), inducing miR-26a and regulating oncogenic EZH2 expression, showing high inhibitory activity against AHCY, and causing growth inhibitio...
T71717 KRAS4b-IN-D14
KRAS4b-IN-D14 is a specific inhibitor of oncogenic KRAS4b signaling which stabilizes the KRAS4b-PDEδ complex and remarkably decreases tumor size and triggered apoptosis of tumor cells.
T68383 BIIB028
BIIB028 is a small-molecule inhibitor of heat shock protein (Hsp) 90 with potential antineoplastic activity. Hsp90 inhibitor BIIB028 blocks the binding of oncogenic client proteins to Hsp90, which may result in the prote...
T10846 CMLD010509 SDS-1-021 Others
CMLD010509 (SDS-1-021) is a highly selective inhibitor of the oncogenic translation program supporting multiple myeloma (MM)-including key oncoproteins such as MDM2, CCND1, MYC, MAF, and MCL-1.
TP1979 NLS-StAx-h
Wnt inhibitor (IC50 = 1.4 μM). Stapled peptide inhibitor of oncogenic Wnt signaling. Inhibits β-catenin-transcription factor interactions. Inhibits proliferation and migration of colorectal cancer cells. Cell permeable.
T29159 WJD008 WJD-008,WJD 008
WJD008 is a dual inhibitor of phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin. WJD008 prevents PI3K signaling and inhibits the proliferation of transformed cells with oncogenic PI3K mutant. WJD008 has ...
T82381 Fmoc-Thr(GalNAc(Ac)3-β-D)-OH
Fmoc-Thr(GalNAc(Ac)3-β-D)-OH impedes the proliferation of cancer cells by selectively interacting with complex oncogenic pathways and enhancing the immune response [1].
T71837 HBX
HBX is a deubiquitinase inhibitor. It inhibits HAdV type 5 (species C, HAdV-C5) replication and oncogenic transformation through inhibition of the cellular pro-viral factor ubiquitin-specific protease 7 (USP7). HBX also ...
T39688 Zeteletinib BOS-172738,DS-5010,Zeteletinib
Zeteletinib (BOS-172738; DS-5010) is a highly potent and selective orally active inhibitor of the RET kinase. It demonstrates nanomolar potency against RET while exhibiting over 300-fold selectivity against VEGFR2. Zetel...
T39927 Zeteletinib hemiadipate BOS-172738 hemiadipate,DS-5010hemiadipate,Zeteletinib hemiadipate
Zeteletinib hemiadipate (BOS-172738; DS-5010) is an orally active compound that functions as a selective inhibitor of RET kinase. It exhibits nanomolar potency against RET and a 300-fold selectivity towards VEGFR2. Notab...
T63970 EZH2-IN-11
EZH2-IN-11 is a potent inhibitor of E2HZ. The oncogenic activity of EZH2 has been demonstrated in numerous studies in a variety of different cancer types and EZH2-IN-11 has shown research potential for cancer diseases.
T75140 CPD-1224
CPD-1224, an orally active derivative that binds cereblon ligands to ALK inhibitors, specifically targets and degrades EML4-ALK oncogenic fusions, including ALK and its mutants L1196M/G1202R.
T68760 Luminespib mesylate
Luminespib, also known as AUY-922, NVP-AUY922, VER52296, is a derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY92...
T64059 G12Si-5
G12Si-5 is a covalent inhibitor of the K-RasG12S mutant with a Ki value of 26 μM. G12Si-5 binds to the S-IIP structural domain and inhibits oncogenic signalling. g12Si-5 reduces ERK phosphorylation levels in KRAS G12S mu...
T78694 SHP2-IN-13
SHP2-IN-13 is an orally active, highly selective allosteric inhibitor targeting the SHP2 “tunnel site,” exhibiting an IC50 of 83.0 nM. It holds potential for research into cancers with RTK oncogenic drivers and diseases ...
T74278 HSP70-IN-3
HSP70-IN-3, a potent inhibitor of HSP70 with IC50 values of 1.1 μM in ASZ001 cells and 1.9 μM in C3H10T1/2 cells, exhibits anti-Hedgehog (Hh) signaling and anti-proliferative activities. Furthermore, it reduces the expre...
T9661 MB710
MB710, an aminobenzothiazole derivative, stabilizes the oncogenic p53 mutation Y220C by binding tightly to the Y220C pocket, enhancing the stability of p53-Y220C with a dissociation constant (Kd) of 4.1 μM. This compound...
T70424 EBI-907
EBI-907 is a highly potent and orally efficacious B-RafV600E inhibitor. EBI-907 displays a low single-digit nanomolar activity (IC50 = 4.9 nM), which is >10-fold more potent than Vemurafenib (IC50 = 59 nM). EBI-907 also...
T26456 A 83586C A83586C,A-83586C
A-83586C is a depsipeptide antibiotic from Streptomyces karnatakensis with potent against Gram-positive activity in vitro. A-83586C acts as a highly potent inhibitor of beta-catenin/TCF4 signaling within cancer cells, wh...
T70004 APS-2-79
APS-2-79, a KSR-dependent MEK antagonist, disrupts ATP (biotin) binding within the KSR2-MEK1 complex, achieving an inhibitory concentration (IC50) of 120 nM. This action stabilizes the KSR inactive state and antagonizes ...
T35538 HPI-1 (hydrate) HPI-1 hydrate
HPI-1 (hydrate) is a Hedgehog (Hh) pathway inhibitor that suppresses signaling through Sonic Hh (IC50= 1.5 μM) without significantly affecting Wnt signaling (IC50≥ 30 μM).1HPI-1 suppresses Hh activation induced by loss o...

Compounds

UNC569
T21302
Synonym: UNC 569
Target: TAM Receptor
PF-3758309
T6626
Synonym: PF-309,PF-03758309,PF 3758309
Target: Apoptosis, PAK
PF-3758309 hydrochloride
T4230
Synonym: PF-03758309 hydrochloride
Target: Apoptosis, PAK
K-Ras(G12C) inhibitor 9
T6556
Synonym:
Target: Raf
YK-4-279
T2275
Synonym:
Target: Apoptosis, DNA/RNA Synthesis
6H05 (TFA)
T7326
Synonym: 6H05 TFA,6H05 trifluoroacetate
Target: Ras
K-Ras(G12C) inhibitor 12
T6555
Synonym:
Target: Apoptosis, Raf, Ras
Ras Inhibitory Peptide acetate
T37422L
Synonym: Ras Inhibitory Peptide acetate(159088-48-9 Free base)
Target: Ras
NRX-1933
T60031
Synonym:
Target:
SI-113
T9589
Synonym:
Target: SGK
XMU-MP-2
T69980
Synonym:
Target: BTK, Protease
BIX02188
T1744
Synonym:
Target: Apoptosis, MEK
Onalespib
T6284
Synonym: AT13387,Onalespib (AT13387)
Target: HSP
Regorafenib Hydrochloride
T8402
Synonym: BAY73-4506 hydrochloride
Target: Raf, VEGFR, c-RET, PDGFR, Autophagy
Aurothiomalate sodium
T20168
Synonym: Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate
Target: Others, PKC
Tuxobertinib
T9072
Synonym: BDTX-189
Target: EGFR, HER, BTK, RIP kinase
RSL3
T3646
Synonym: RSL3 1S,1S,3R-RSL3
Target: Ferroptosis, GPX, Glutathione Peroxidase
Phthalazinone pyrazole
T21981
Synonym:
Target: Aurora Kinase
BI-882370
TQ0048
Synonym:
Target: Raf
GMB-475
T8488
Synonym:
Target: Bcr-Abl
Linsitinib
T6017
Synonym: OSI-906
Target: IGF-1R
CHD1Li 6.11
T63049
Synonym:
Target: Others
KW-2450 free base
T68405
Synonym:
Target: IGF-1R
SML-10-70-1
T70476
Synonym:
Target:
MB725
T33219
Synonym: MB 725,MB-725
Target:
Murayaquinone
T71635
Synonym:
Target:
6H05
T1931
Synonym: K-Ras inhibitor
Target: Raf, Ras
SNIPER(ABL)-38
T34670
Synonym:
Target:
KRAS4b-PDEδ stabilizer C19
T32419
Synonym:
Target:
Aristeromycin diphosphate
T69264
Synonym:
Target:
KRAS4b-IN-D14
T71717
Synonym:
Target:
BIIB028
T68383
Synonym:
Target:
CMLD010509
T10846
Synonym: SDS-1-021
Target: Others
NLS-StAx-h
TP1979
Synonym:
Target:
WJD008
T29159
Synonym: WJD-008,WJD 008
Target:
Fmoc-Thr(GalNAc(Ac)3-β-D)-OH
T82381
Synonym:
Target:
HBX
T71837
Synonym:
Target:
Zeteletinib
T39688
Synonym: BOS-172738,DS-5010,Zeteletinib
Target:
Zeteletinib hemiadipate
T39927
Synonym: BOS-172738 hemiadipate,DS-5010hemiadipate,Zeteletinib hemiadipate
Target:
EZH2-IN-11
T63970
Synonym:
Target:
CPD-1224
T75140
Synonym:
Target:
Luminespib mesylate
T68760
Synonym:
Target:
G12Si-5
T64059
Synonym:
Target:
SHP2-IN-13
T78694
Synonym:
Target:
HSP70-IN-3
T74278
Synonym:
Target:
MB710
T9661
Synonym:
Target:
EBI-907
T70424
Synonym:
Target:
A 83586C
T26456
Synonym: A83586C,A-83586C
Target:
APS-2-79
T70004
Synonym:
Target:
HPI-1 (hydrate)
T35538
Synonym: HPI-1 hydrate
Target:
1 2
カタログ番号 製品名 別名 ターゲット
T3763 Fumaric acid Lichenic acid,Fumarate,2-Butenedioic acid,Trans-Butenedioic acid,Donitic acid,Allomaleic acid Endogenous Metabolite
Fumaric acid (2-Butenedioic acid) attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Fumaric acid has recently been identified as an oncometabolite or a...
T6S1683 Demethoxycurcumin Curcumin II,Desmethoxycurcumin,Monodemethoxycurcumin Apoptosis , Antioxidant , Antibacterial , Autophagy
1. Demethoxycurcumin (Desmethoxycurcumin) has antioxidant activity. 2. Demethoxycurcumin has anti-inflammatory activity. 3. Demethoxycurcumin has anti-proliferative activity. 4. Demethoxycurcumin has anti-acanthamoebic e...
T40667 L-Azatyrosine
L-Azatyrosine, an antitumor antibiotic derived from Streptomyces chibaensis, exhibits the ability to restore the normal phenotypic behavior of transformed cells that carry oncogenic Ras genes.
TN4028 Euchrestaflavanone B PARP , Antifection
Euchrestaflavanone B shows antibacterial activity against Gram positive bacteria, Staphylococcus aureus, Bacillus subtilis and Bacillus cereus. Euchrestaflavanone B may function by inhibiting oncogenic disease, at least ...
T82326 Genkwadaphnin
Genkwadaphnin, a daphnane diterpenoid, targets importin-β1, reducing the nuclear accumulation of CRPC drivers and suppressing downstream oncogenic signaling. Demonstrating potent anti-tumor effects, it inhibits castratio...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-03382 FGF-6 Protein, Human, Recombinant Human E. coli
FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, includi...
TMPY-04125 PTP1B Protein, Human, Recombinant (His) Human E. coli
PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c...
TMPY-02869 MMP-12 Protein, Human, Recombinant (catalytic domain) Human E. coli
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPJ-00375 HGF Protein, Human, Recombinant (His) Human HEK293 Cells
HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propepti...
TMPH-00546 Epstein-Barr virus (strain GD1) BARF1 Protein (His) EBV E. coli
Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro.
TMPH-00547 Epstein-Barr virus (strain B95-8) BARF1 Protein (His & Myc) EBV E. coli
Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro.
TMPK-01381 CSPG4/MCSP Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
The chondroitin sulfate proteoglycan-4 (CSPG4) is a cell surface proteoglycan overexpressed in a huge range of human and canine neoplastic lesions by tumor cells, tumor microenvironment and cancer initiating cells. CSPG4...
TMPK-00927 ALK Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Anaplastic lymphoma kinase (ALK) is mostly known for its oncogenic role in several human cancers. Recent evidences clearly indicate new roles of ALK and its genetic aberrations (e.g. gene rearrangements and mutations) in...
TMPK-00479 AGER Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
The receptor for advanced glycation end products (AGER) is an oncogenic transmembranous receptor up-regulated in various human cancers. AGER promotes proliferation, migration, and inhibits apoptosis of squamous cervical ...
TMPJ-00703 Gankyrin Protein, Human, Recombinant Human E. coli
Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblast...
TMPK-00828 Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc) Human HEK293 Cells
MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire...
TMPY-00361 Pellino-1 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
PELI is a family of E3 ubiquitin ligases that regulate protein activity through a post-translational modification, ubiquitination. PELI1 may function to control inadvertent activation of RIP3, thus preventing aberrant ce...
TMPY-01584 PR-Set7 Protein, Human, Recombinant Human E. coli
KMT5A (known as PR-Set7/9, SETD8 and SET8), a member of the SET domain containing methyltransferase family specifically targeting H4K20 for methylation, has been implicated in multiple biological processes. Inhibition of...
TMPH-02835 PDGFD Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role ...
TMPK-01045 IL-20RA Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
IL-20RA was highly expressed in the tumor tissue of CRC and related to the advanced stage.IL-20RA was involved in regulating oncogenic and immune pathways and affecting the expression of genes related to cell proliferati...
TMPK-00948 CDH17 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00952 CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc) Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-01224 CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated Mouse HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00555 CDH17 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00473 CDH17 Protein, Rhesus macaque, Recombinant (His) Rhesus HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-01223 CDH17 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00953 CDH17 Domain 6-7 Protein, Human, Recombinant (mFc) Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00949 CDH17 Domain 7 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00947 CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00950 CDH17 Domain 6-7 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPY-04205 AGR3 Protein, Human, Recombinant (mFc) Human HEK293 Cells
Anterior gradient protein (AGR) 3 is a highly related homologue of pro-oncogenic AGR2 and belongs to the family of protein disulfide isomerases. AGR3 was found in breast, ovary, prostate, and liver cancer, it is associat...
TMPY-03125 SHP-2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
SHP2, also known as PTPN11, belongs to the protein-tyrosine phosphatase(PTP) family, non-receptor class 2 subfamily. PTPs catalyze the removal of phosphate groups from tyrosine residues by the hydrolysis of phosphoric ac...
TMPH-02312 Wilms tumor protein/WT1 Protein, Human, Recombinant (His & SUMO) Human E. coli
Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO....
TMPJ-00465 PTP1C Protein, Human, Recombinant (His) Human E. coli
Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mi...
TMPK-00951 CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPJ-01113 RCN2 Protein, Human, Recombinant (His) Human HEK293 Cells
Reticulocalbin-2 (RCN2, also named as ERC-55), is a 55-kDa Ca2+-binding protein containing six EF-hands, which was identified to be localized in endoplasmic reticulum. RCN2 is belonging to Reticulocalbin (RCN) family, th...
TMPY-03296 SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST) Mouse Baculovirus Insect Cells
PTPN6 is an enzyme that belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and onco...
TMPY-03047 Stathmin 1 Protein, Human, Recombinant (His) Human E. coli
Stathmin1 (STMN1) is a cytosolic phosphoprotein that regulates cellular microtubule dynamics and is known to have oncogenic activity. STMN1 is a possible biomarker for paclitaxel sensitivity and poor prognosis in GC and ...
TMPY-03263 RUVBL1 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
RUVBL1, also known as RVB1, is a component of the NuA4 histone acetyltransferase complex and belongs to the RuvB family. RUVBL1 is ubiquitously expressed with high expression in heart, skeletal muscle and testis. It poss...
TMPJ-00319 PFKFB3 Protein, Human, Recombinant (His) Human E. coli
Fructose-2,6-biphosphatase 3, also known as 6-phosphofructo-2-kinase or PFK2 or PFKFB3, involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls the activity of the...
TMPY-04474 PFKFB3 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Fructose-2,6-biphosphatase 3, also known as 6-phosphofructo-2-kinase or PFK2 or PFKFB3, is a potent activator of phosphofructokinase, which is a rate-limiting enzyme of glycolysis. Highly phosphorylated PFKFB3 protein wa...
TMPY-02763 DEP-1 Protein, Human, Recombinant (aa 997-1337, His) Human E. coli
DEP1 / PTPRJ (Receptor-type tyrosine-protein phosphatase eta) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, includin...
TMPY-03795 EIF5A2 Protein, Human, Recombinant (His) Human E. coli
Eukaryotic translation initiation factor 5A2 (EIF5A2) has been demonstrated to be upregulated in numerous types of human cancer and is associated with cancer progression. Silencing of EIF5A2 in the NSCLC cells resulted i...
TMPY-02198 ILKAP Protein, Human, Recombinant (His) Human HEK293 Cells
Integrin-linked kinase-associated serine/threonine phosphatase 2C, also known as ILKAP, is a cytoplasm protein that belongs to the PP2C family. ILKAP contains one PP2C-like domain. ILKAP is widely expressed. Highest leve...
TMPH-01273 TRIP12 Protein, Human, Recombinant (His & Myc) Human E. coli
E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein a...
TMPY-01769 4EBP1 Protein, Human, Recombinant (His) Human E. coli
The translational suppressor eIF4E binding protein-1, 4E-BP1 functions as a key regulator in cellular growth, differentiation, apoptosis and survival. The Eif4ebp1 gene, encoding 4E-BP1, is a direct target of a transcrip...
TMPY-02527 P53R2 Protein, Human, Recombinant (His) Human E. coli
Ribonucleoside reductase subunit M2B, also known as RRM2B or p53R2, is an enzyme belonging to the iron-dependent ribonucleotide reductase (RNR) enzyme family which is essential for DNA synthesis. Ribonucleotide reductase...
FGF-6 Protein, Human, Recombinant
TMPY-03382
Species: Human
Expression System: E. coli
PTP1B Protein, Human, Recombinant (His)
TMPY-04125
Species: Human
Expression System: E. coli
MMP-12 Protein, Human, Recombinant (catalytic domain)
TMPY-02869
Species: Human
Expression System: E. coli
HGF Protein, Human, Recombinant (His)
TMPJ-00375
Species: Human
Expression System: HEK293 Cells
Epstein-Barr virus (strain GD1) BARF1 Protein (His)
TMPH-00546
Species: EBV
Expression System: E. coli
Epstein-Barr virus (strain B95-8) BARF1 Protein (His & Myc)
TMPH-00547
Species: EBV
Expression System: E. coli
CSPG4/MCSP Protein, Cynomolgus, Recombinant (His)
TMPK-01381
Species: Cynomolgus
Expression System: HEK293 Cells
ALK Protein, Mouse, Recombinant (hFc)
TMPK-00927
Species: Mouse
Expression System: HEK293 Cells
AGER Protein, Cynomolgus, Recombinant (His)
TMPK-00479
Species: Cynomolgus
Expression System: HEK293 Cells
Gankyrin Protein, Human, Recombinant
TMPJ-00703
Species: Human
Expression System: E. coli
Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)
TMPK-00828
Species: Human
Expression System: HEK293 Cells
Pellino-1 Protein, Human, Recombinant (His & GST)
TMPY-00361
Species: Human
Expression System: Baculovirus Insect Cells
PR-Set7 Protein, Human, Recombinant
TMPY-01584
Species: Human
Expression System: E. coli
PDGFD Protein, Mouse, Recombinant (His & SUMO)
TMPH-02835
Species: Mouse
Expression System: E. coli
IL-20RA Protein, Mouse, Recombinant (hFc)
TMPK-01045
Species: Mouse
Expression System: HEK293 Cells
CDH17 Protein, Human, Recombinant (hFc)
TMPK-00948
Species: Human
Expression System: HEK293 Cells
CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc)
TMPK-00952
Species: Human
Expression System: HEK293 Cells
CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
TMPK-01224
Species: Mouse
Expression System: HEK293 Cells
CDH17 Protein, Cynomolgus, Recombinant (His)
TMPK-00555
Species: Cynomolgus
Expression System: HEK293 Cells
CDH17 Protein, Rhesus macaque, Recombinant (His)
TMPK-00473
Species: Rhesus
Expression System: HEK293 Cells
CDH17 Protein, Mouse, Recombinant (His)
TMPK-01223
Species: Mouse
Expression System: HEK293 Cells
CDH17 Domain 6-7 Protein, Human, Recombinant (mFc)
TMPK-00953
Species: Human
Expression System: HEK293 Cells
CDH17 Domain 7 Protein, Human, Recombinant (hFc)
TMPK-00949
Species: Human
Expression System: HEK293 Cells
CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00947
Species: Human
Expression System: HEK293 Cells
CDH17 Domain 6-7 Protein, Human, Recombinant (hFc)
TMPK-00950
Species: Human
Expression System: HEK293 Cells
AGR3 Protein, Human, Recombinant (mFc)
TMPY-04205
Species: Human
Expression System: HEK293 Cells
SHP-2 Protein, Mouse, Recombinant (His)
TMPY-03125
Species: Mouse
Expression System: HEK293 Cells
Wilms tumor protein/WT1 Protein, Human, Recombinant (His & SUMO)
TMPH-02312
Species: Human
Expression System: E. coli
PTP1C Protein, Human, Recombinant (His)
TMPJ-00465
Species: Human
Expression System: E. coli
CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00951
Species: Human
Expression System: HEK293 Cells
RCN2 Protein, Human, Recombinant (His)
TMPJ-01113
Species: Human
Expression System: HEK293 Cells
SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST)
TMPY-03296
Species: Mouse
Expression System: Baculovirus Insect Cells
Stathmin 1 Protein, Human, Recombinant (His)
TMPY-03047
Species: Human
Expression System: E. coli
RUVBL1 Protein, Human, Recombinant (His)
TMPY-03263
Species: Human
Expression System: Baculovirus Insect Cells
PFKFB3 Protein, Human, Recombinant (His)
TMPJ-00319
Species: Human
Expression System: E. coli
PFKFB3 Protein, Human, Recombinant (His & GST)
TMPY-04474
Species: Human
Expression System: Baculovirus Insect Cells
DEP-1 Protein, Human, Recombinant (aa 997-1337, His)
TMPY-02763
Species: Human
Expression System: E. coli
EIF5A2 Protein, Human, Recombinant (His)
TMPY-03795
Species: Human
Expression System: E. coli
ILKAP Protein, Human, Recombinant (His)
TMPY-02198
Species: Human
Expression System: HEK293 Cells
TRIP12 Protein, Human, Recombinant (His & Myc)
TMPH-01273
Species: Human
Expression System: E. coli
4EBP1 Protein, Human, Recombinant (His)
TMPY-01769
Species: Human
Expression System: E. coli
p53R2 Protein, Human, Recombinant (His)
TMPY-02527
Species: Human
Expression System: E. coli
カタログ番号 製品名
L9420 Exosome Compound Library

76 compounds
76 exosome-related compounds that can be used for high-throughput and high-content screening.