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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T10404 | ATP synthase inhibitor 1 | ATPase | |
ATP synthase inhibitor 1 is an inhibitor of the c subunit of the F1/FO-ATP synthase complex. It inhibits mitochondrial permeability transition pore (mPTP) opening and does not affect ATP levels. | |||
T4380 | Ac-CoA Synthase Inhibitor1 | ACSS2 inhibitor | RSV , Fatty Acid Synthase |
Ac-CoA Synthase Inhibitor1 (ACSS2 inhibitor) is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2). | |||
T27066 | Prostaglandin G/H synthase 1 inhibitor | CP74006,CP 74006,2-Amino-N-(4-chlorophenyl)benzamide | Others |
Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM. | |||
T61147 | Chitin synthase inhibitor 4 | Antibiotic | |
Chitin synthase inhibitor 4 is a chitin synthase (CHS) inhibitor with antimicrobial activity.Chitin synthase inhibitor 4 is a CHS-based compound and a candidate fungicide. | |||
T39883 | Polyketide synthase 13-IN-1 | ||
Polyketide synthase 13-IN-1 (compound 32) is a polyketide synthase 13 inhibitor. | |||
T39693 | Polyketide synthase 13-IN-3 | ||
Polyketide synthase 13-IN-3 (compound 41) is a potent inhibitor of polyketide synthase 13, demonstrating a minimum inhibitory concentration (MIC) range of 0.0625-0.125 μg/mL against the M. tuberculosis strain H37Rv. | |||
T38168 | S.pombe lumazine synthase-IN-1 | ||
S.pombe lumazine synthase-IN-1 is a compound that inhibits lumazine synthases, demonstrating Ki values of 243 μM for Schizosaccharomyces pombe and 9.6 μM for Mycobacterium tuberculosis, respectively[1]. | |||
T40945 | Phospho-Glycogen Synthase Peptide-2(substrate) | ||
Phospho-Glycogen Synthase Peptide-2, a substrate for glycogen synthase kinase-3 (GSK-3), serves as a peptide substrate effective in the affinity purification of protein-serine kinases. | |||
T75397 | Hyaluronan synthase (PmHAS) | ||
Hyaluronan synthase (PmHAS), a membrane protein, catalyzes the biosynthesis of hyaluronic acid (HA) by utilizing only Mg+2 along with two sugar-UDP substrates, GlcUA-UDP and GlcNAc-UDP, to polymerize HA chains [1] [2]. | |||
T62475 | Chitin synthase inhibitor 7 | ||
Chitin synthase inhibitor 7 (compound 9c) is a potent inhibitor of chitin synthase (CHS) (IC50: 0.37 nM). synthase inhibitor 7 can be used to study fungal infections. | |||
T62701 | Dihydropteroate synthase-IN-1 | ||
Dihydropteroate synthase-IN-1 (compound 5g) is a potent inhibitor of dihydropteroate synthase (DHPS) with inhibitory effects on cytochrome P450. Dihydropteroate synthase-IN-1 can be used as a diagnostic radiographic mate... | |||
T62738 | Chitin synthase inhibitor 6 | ||
Chitin synthase inhibitor 6 (compound 9b) is a potent inhibitor of chitin synthase (CHS) (IC50: 0.21 mM). chitin synthase inhibitor 6 exhibits broad-spectrum antifungal effects against drug-resistant fungi and can be use... | |||
T62739 | Chitin synthase inhibitor 9 | ||
Chitin synthase inhibitor 9 is a chitin synthase (CHS) inhibitor that exhibits broad-spectrum antifungal activity and can be used in studies of fungal infections. | |||
T62246 | Chitin synthase inhibitor 8 | ||
Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infections. | |||
T61398 | Chitin synthase inhibitor 3 | ||
Chitin Synthase Inhibitor 3 (Compound 2d) is a potent inhibitor of chitin synthase, exhibiting an IC50 value of 0.16 mM and demonstrating antifungal activity with a minimum inhibitory concentration (MIC) of 1 μg/mL again... | |||
T81109 | Squalene synthase-IN-1 | ||
Squalene synthase-IN-1 (compound 1) is a potent antihyperlipidemic agent that inhibits Squalene Synthase and demonstrates exceptional antioxidant and anti-inflammatory activities. It significantly reduces both glucose an... | |||
T61188 | Chitin synthase inhibitor 2 | ||
Chitin synthase inhibitor 2 (compound 2b) is a highly potent inhibitor of chitin synthase, with an IC50 value of 0.09 mM and a K i value of 0.12 mM. This compound exhibits antimicrobial activities in vitro and demonstrat... | |||
T74956 | Chitin synthase inhibitor 10 | ||
Chitin Synthase Inhibitor 10, as a potent chitin synthase inhibitor, exhibits remarkable inhibitory activity with an IC50 of 0.11 mM. It also functions as an antifungal agent, demonstrating substantial effectiveness agai... | |||
T63392 | Chitin synthase inhibitor 5 | ||
Chitin synthase inhibitor 5 is a lipophilic calpain inhibitor, and they showed moderate to good anti-proliferative effects in vitro. | |||
T79481 | Chitin synthase inhibitor 13 | ||
Chitin Synthase Inhibitor 13 (compound 12g), a non-competitive antagonist of chitin synthase, demonstrates broad-spectrum antifungal activity and has an inhibition concentration (IC50) of 106.7 μM [1]. | |||
T61649 | ATP synthase inhibitor 2 | ||
ATP Synthase Inhibitor 2, a compound targeting Pseudomonas aeruginosa (PA) ATP synthase with an IC50 of 10 μg/mL, fully inhibits the ATP synthesis activity of PA at a concentration of 128 μg/mL [1]. | |||
T62068 | Chitin synthase inhibitor 1 | ||
Chitin synthase inhibitor 1 is a potent and selective chitin synthase (CHS) inhibitor with IC50 of 0.12 mM. Chitin synthase inhibitor 1 potently inhibits drug-resistant fungi variants. | |||
T63077 | Chitin synthase inhibitor 12 | ||
Chitin synthase inhibitor 12, a Chitin synthase (CHS) inhibitor, showed excellent CHS inhibition (IC50: 0.16 mM). Chitin synthase inhibitor 12 is also a broad-spectrum antifungal agent resistant to resistant fungal varia... | |||
T61632 | Glucosylceramide synthase-IN-3 | ||
Glucosylceramide synthase-IN-3 (compound BZ1) is a highly potent, brain-penetrant, and orally active inhibitor of glucosylceramide synthase (GCS), exhibiting an IC50 value of 16 nM for human GCS. This compound, designate... | |||
T62898 | Glucosylceramide synthase-IN-1 | ||
Glucosylceramide synthase-IN-1 (T-036) is a potent, orally active, blood-brain barrier permeable glucosylceramide synthase (GCS) inhibitor that acts on human GCS (IC50: 31 nM) and mouse GCS (IC50: 51 nM). Glucosylceramid... | |||
T62664 | Glucosylceramide synthase-IN-2 | ||
Glucosylceramide synthase-IN-2 (compound T-690) is a potent, blood-brain barrier-permeable, orally active inhibitor of glucosylceramide synthase (GCS) that acts on human GCS (IC50: 15 nM) and mouse GCS (IC50: 190 nM). Gl... | |||
T78886 | Chitin synthase inhibitor 14 | ||
Chitin Synthase Inhibitor 14 (compound 4n), a potent chitin synthase (CHS) inhibitor, exhibits antifungal activity and is effective against drug-resistant fungal strains [1]. | |||
T63353 | Chitin synthase inhibitor 11 | ||
Chitin synthase inhibitor 11 is a potent chitin synthase (CHS) inhibitor that significantly inhibits CHS activity (IC50: 0.10 mM) and has broad-spectrum in vitro fungal inhibition. | |||
TP2195 | Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell | Others | |
Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell (Ac-Pro-Tyr-Asn-Ser-Ser-Pro-Arg-Pro-Glu-Gln-His-Lys-Ser-Tyr-Lys-Cys) is a peptide that inhibits the function of NOSs as a result it blocks the pro... | |||
T60877 | Mtb ATP synthase-IN-1 | ||
Mtb ATP synthase-IN-1 (compound 6ab) can be used in anti-mycobacterium research. Mtb ATP synthase-IN-1 shoys low cytotoxicity (Vero IC 50 > 64 μg/mL) and acceptable oral bioavailability that has good metabolic stability.... | |||
T61598 | Polyketide synthase 13-IN-2 | ||
Polyketide synthase 13-IN-2 (comp 42) is a potent inhibitor of polyketide synthase 13 in Mycobacterium tuberculosis. It demonstrates a minimum inhibitory concentration (MIC) of 0.25 μg/mL [1]. | |||
T79004 | ATP synthase inhibitor 2 TFA | ||
ATP Synthase Inhibitor 2 (Compound 22) TFA is a potent inhibitor of Pseudomonas aeruginosa ATP synthase with an IC50 value of 10 μg/mL. It effectively halts ATP synthesis in Pseudomonas aeruginosa at a concentration of 1... | |||
T61784 | GlcN-6-P Synthase-IN-1 | ||
GlcN-6-P Synthase-IN-1 (Compound 4d) is a potent inhibitor of Glucosamine-6-phosphate (GlcN-6-P) synthase, with an IC50 of 3.47 μM. This compound demonstrates remarkable antimicrobial activity and exhibits excellent pene... | |||
T76380 | [Ala9,10, Lys11,12] Glycogen Synthase (1-12) | ||
[Glycogen Synthase (1-12) Ala9,10, Lys11,12] is a selective substrate for protein kinase C (PKC) phosphorylation. It serves to assess PKC activity [1]. | |||
T9987 | GSK3-IN-1 | GSK-3 | |
GSK3-IN-1 is a GSK3B-glycogen synthase kinase-3 beta inhibitor. | |||
T75808 | Phospho-Glycogen Synthase Peptide-2(substrate) TFA | ||
Phospho-Glycogen Synthase Peptide-2 (substrate) serves as a peptide substrate for glycogen synthase kinase-3 (GSK-3) and is utilized for the affinity purification of protein-serine kinases [1]. | |||
T2681 | HPGDS-IN-1 | PGE Synthase | |
hPGDS-IN-1 is a hPGDS inhibitor. | |||
T1866 | AT-56 | Others , PGE Synthase | |
AT56, a specific inhibitor of prostaglandin D2 synthase enzymatic activity, blunted adipogenic aldosterone effects. | |||
T1965 | Bikinin | Abrasin | Others , GSK-3 |
Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor. | |||
T15373 | Gboxin | ATPase , Mitochondrial Metabolism | |
Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity. | |||
T5956 | VP3.15 dihydrobromide | GSK-3 , PDE | |
VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE7- glycogen synthase kinase (GSK)3 inhibitor(with IC50s of 1.59 μM , 0.88 μM,respectively.) | |||
T10202 | A 1070722 | GSK-3 | |
T1755 | LY2090314 | GSK-3 | |
LY2090314, an effective GSK-3α/β inhibitor (IC50: 1.5 nM/0.9 nM), may improve the efficacy of platinum-based chemotherapy regimens. LY2090314 has been used in trials studying the treatment of Leukemia, Advanced Cancer, a... | |||
T1957 | AZD2858 | GSK-3 | |
AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating Wnt signaling pathway. | |||
T1741 | AZD1080 | GSK-3 | |
AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor. | |||
T9213 | G140 | cGAS | |
G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS). | |||
T2166 | TWS119 | GSK-3 , Autophagy | |
TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiation | |||
T9611 | PF-04802367 | GSK-3 | |
PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay. It shows desirable central nervous system (CNS) properties and ... | |||
T7948 | HPGDS inhibitor 2 | GSK-2894631A | PGE Synthase |
HPGDS inhibitor 2 (GSK-2894631A) is a potent, selective hematopoietic prostaglandin D synthase (h-pgds) inhibitor, IC50 = 9.9 nm. | |||
T5843L | (S)-Flurbiprofen | esflurbiprofen | COX , PGE Synthase |
Esflurbiprofen is an inhibitor of COX-1 and COX-2. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T2S2335 | Dehydroevodiamine | DHED | Others , NF-κB , COX , PGE Synthase , NO Synthase |
Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood fl... | |||
T5681 | ETHYL CAFFEATE | ETHYL 3,4-DIHYDROXYCINNAMATE | NF-κB , COX , PGE Synthase , NO Synthase |
Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro. Furthermore, Ethyl Caffeate intensely blocked the transcriptional expression in interferon-γ-related s... | |||
TQ0260 | Cerulenin | Antibiotic , Antifungal , Fatty Acid Synthase | |
Cerulenin is a natural inhibitor of fatty acid synthase (FAS). It is produced by the fungus Cephalosporium caeruleus. | |||
T4S0227 | Sinensetin | Pedalitin permethyl ether | TNF , PGE Synthase |
Sinensetin (Pedalitin permethyl ether) is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin enhances adipogenesis and lipolysis. | |||
T6S2023 | Harpagoside | Others , COX , NO Synthase | |
1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression... | |||
TQ0301 | Kuwanon A | NO Synthase | |
T5727 | CAFESTOL | ERK , NF-κB , COX , PGE Synthase | |
CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production... | |||
T6S1665 | Irisflorentin | Others , NO Synthase | |
1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechan... | |||
T2824 | Pedunculoside | Others , Fatty Acid Synthase | |
Pedunculoside is extracted from Ilex rotunda Thunb. | |||
T7682 | Asymmetric dimethylarginine | Endogenous Metabolite , NO Synthase , NOD | |
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS) | |||
T2S0765 | Epibetulinic acid | NO Synthase , Prostaglandin Receptor | |
Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin. | |||
TN6772 | Malabaricone C | Others | |
Malabaricone C is a bioactive chemical. | |||
T3847 | Asperuloside | Asperulosid | Others , NO Synthase |
Asperuloside (Asperulosid) has anti-inflammatory activity. | |||
T5838 | L-Canavanine sulfate | NO Synthase , NOD | |
L-Canavanine sulfate is a selective inducible NO synthase inhibitor. | |||
T5S0285 | Cistanoside A | Others | |
1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respirat... | |||
T5S0246 | Pseudoprotodioscin | Others , Fatty Acid Synthase | |
1. Pseudoprotodioscin has moderate cytotoxicity. | |||
T6323 | Oligomycin A | MCH 32 | ATPase , Antibiotic , Antifungal |
Oligomycin A (MCH 32) is an inhibitor of ATP synthase, inhibits oxidative phosphorylation and all the ATP-dependent processes occurring on the coupling membrane of mitochondria. | |||
TJS0387 | Desoxyrhaponticin | Deoxyrhapontin,Deoxyrhaponticin | Apoptosis , Fatty Acid Synthase |
1. Desoxyrhaponticin (Deoxyrhaponticin) is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least... | |||
T7597 | 6-Biopterin | L-Biopterin | Endogenous Metabolite , NO Synthase , NOD |
6-Biopterin (L-Biopterin) is a natural product,is a NO synthase cofactor. | |||
T2791 | Pectolinarin | Apoptosis , Others , NO Synthase , Prostaglandin Receptor , Interleukin | |
Pectolinarin is a Cirsium isolate with anti-inflammatory activity. | |||
T4808 | Agmatine sulfate | Agmatine sulfate salt | Endogenous Metabolite , NO Synthase , Imidazoline Receptor |
Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide sy... | |||
TN2139 | Regaloside B | NOS , COX , NO Synthase | |
Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitric oxide synthase) and COX-2 (cyclooxygenase-2). | |||
T2980 | Chondroitin sulfate | Chonsurid,Chondroitin polysulfate | MMP , Others , Endogenous Metabolite , NO Synthase |
Chondroitin sulfate (Chonsurid) is extracted from shark bone;Store the product in sealed, cool and dry condition | |||
T3121 | Betulin | Trochol,betulinic alcohol,betuline,betulinol,Betulol | Apoptosis , Endogenous Metabolite , Lipid , Fatty Acid Synthase |
Betulin (betulinol) (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene. It is commonly isolated from the bark of birch trees where it forms up to 30% of the dry weight of the extractive and is fo... | |||
T1310 | 2-Thiouracil | Thiouracil,Deracil | Thyroid hormone receptor(THR) , NO Synthase |
2-Thiouracil (Deracil) is a thiolated uracil derivative that is a known anti-hyperthyroid agent. | |||
T3S0364 | L-Arginine | L-Arg,(S)-(+)-Arginine | IL Receptor , Endogenous Metabolite , NO Synthase |
1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate... | |||
TN1373 | α-Humulene | Alpha-caryophyllene | TNF , NOS , COX |
α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory effects, probably by interfering with TNFalpha production an... | |||
T7030 | Anemarsaponin B | p38 MAPK , NF-κB , MEK , COX , NO Synthase | |
Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B c... | |||
T7786 | Tryptanthrin | DNA gyrase | |
Tryptanthrin is a natural DNA gyrase inhibitor. | |||
T3322 | Trans-Chalcone | Chalcone,Cinnamophenone,Chalkone | Apoptosis , Others , Antifungal , Fatty Acid Synthase |
trans-Chalcone (Chalkone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones. | |||
T5684 | Ethyl 3,4-dihydroxybenzoate | Apoptosis , Others , Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , NO Synthase , Autophagy | |
Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain. | |||
T3918 | Ginsenoside Rb3 | Gypenoside IV | NF-κB , COX , NO Synthase |
Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity. It also inhibits the induction of COX-2 and iNOS mRNA. | |||
T0983 | Penicillamine | d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine | Antibiotic |
Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl a... | |||
T3779 | Crocin II | Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B | Caspase , COX , NO Synthase |
Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expres... | |||
T3805 | Prim-O-glucosylcimifugin | Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside | TNF , COX , JAK , NO Synthase |
Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC(smooth muscle cell) stimulated by TNF-alpha, increase the proportion of G0/G1 phase. | |||
T4S1173 | Agrimol B | Sirtuin , PPAR | |
1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb. | |||
T3811 | Ginsenoside C-K | Ginsenoside compound K,Ginsenoside K | P450 , cell cycle arrest , COX , NO Synthase |
Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2. | |||
T3324 | Lycorine | Galanthidine,Narcissine,Amarylline,Belamarine,Licorine | Apoptosis , Virus Protease , Antibacterial , AChR , Fatty Acid Synthase |
Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive. | |||
T5S0754 | Isoquercetin | 3-Glucosylquercetin,Hirsutrin,Isoquercitrin,Quercetin 3-o-glucopyranoside | NF-κB , Wnt/beta-catenin , NO Synthase |
1. Isoquercetin (3-Glucosylquercetin) is a potential stimulator of bone mineralization used for prophylaxis of osteoporotic disorders. 2. Isoquercetin may be as a potential therapeutic agent against neurodegeneration in ... | |||
T2758 | Madecassic acid | 6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose | Others , TNF , COX , NO Synthase , Interleukin |
Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica. | |||
T3S0401 | Piceatannol 3'-O-glucoside | Piceatannol 3-glycoside,Quzhaqigan | Arginase , NO Synthase |
Piceatannol 3'-O-glucoside (Piceatannol 3-glycoside) increases pulmonary blood oxygen tension and decreases pulmonary interstitial edema, so it can protect lung injury. | |||
T0670 | L-Arginine hydrochloride | (S)-(+)-Arginine hydrochloride,L-Arginine HCl (L-Arg),L-arginine monohydrochloride | Amino Acids and Derivatives , Endogenous Metabolite , NO Synthase |
L-Arginine hydrochloride is a nitrogen donor for synthesis of nitric oxide. | |||
T4S1421 | Praeruptorin B | Praeruptorin D | NPC1L1 , Fatty Acid Synthase |
Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs). It can also significantly up-regulate CYP3A4 expression and activity via the PXR-mediated pathway. | |||
TN1102 | Physalin L | Others , NO Synthase | |
Physalin L is a natural product,it shows a distinct fluorescence spot under UV 365 nm with good separation. | |||
TN1109 | 3-O-Acetyl-16α-hydroxydehydrotrametenolic acid | 3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid | NOS , NO Synthase , Prostaglandin Receptor |
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid (3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid) shows anti-inflammatory activity, it can inhibit NO production and iNOS expression in LPS-stimulated Raw264.7 cells. | |||
T13686 | Ergolide | NF-κB | |
Ergolide, a sesquiterpene lactone extracted from the dried flowers of Inula Britannica, effectively hinders the expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in RAW 264.7 macrophages by deactivating... | |||
T12039 | Miglustat | N-Butyldeoxynojirimycin,OGT918,NB-DNJ | Others |
Miglustat (NB-DNJ) is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1). | |||
T17056 | Tetrahydrobiopterin | Sapropterin,BH4,(Rac)-Sapropterin | NOS , Endogenous Metabolite |
Tetrahydrobiopterin (BH4) is a cofactor for aromatic amino acid hydroxylases and an essential cofactor for nitric oxide synthase (NOS), which is used in the study of endothelial dysfunction such as hypertension, hypercho... | |||
T5267 | N-Acetyl-L-glutamic acid | Ac-L-Glu-OH,N-Acetylglutamic acid | Others , Endogenous Metabolite |
N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu activates carbamoyl phospha... | |||
T9267 | Aureobasidin A | Others , Antifungal | |
Aureobasidin A is a cyclic peptide and an antifungal antibiotic. Aureobasidin A is an inhibitor of the inositolphosphorylceramide synthase AUR1. | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-03120 | Prostaglandin D2 Synthase Protein, Human, Recombinant (His) | Human | HEK293 |
PTGDS, also known as L-PGDS, belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic mole... | |||
TMPY-04070 | Citrate Synthase Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Chondroitin sulphate (CS) glycosaminoglycan chains on cell and extracellular matrix proteoglycans (PGs) can no longer be regarded as merely hydrodynamic space fillers. Overwhelming evidence over recent years indicates th... | |||
TMPY-04356 | GSK3B Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It Contains 1 protein kinase domain, and is expressed in the testis, thymus, prostate, and ovary and weakly expressed in the lung, ... | |||
TMPY-05069 | Prostaglandin D2 Synthase Protein, Rat, Recombinant (His) | Rat | HEK293 |
PTGDS, also known as L-PGDS, belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic mole... | |||
TMPH-03412 | Citrate synthase Protein, Rickettsia australis, Recombinant (His & Myc) | Rickettsia australis | E. coli |
Citrate synthase Protein, Rickettsia australis, Recombinant (His & Myc) is expressed in E. coli with N-terminal 10xHis tag and C-terminal Myc tag. The predicted molecular weight is 53.6 kDa. Accession number: P51039 | |||
TMPH-03585 | Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His) | Staphylococcus haemolyticus | E. coli |
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | |||
TMPH-00709 | DAHP synthase Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). | |||
TMPY-04624 | Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
PTGDS, also known as L-PGDS, belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic mole... | |||
TMPH-03057 | Chorismate synthase Protein, Neurospora crassa, Recombinant (His) | Neurospora crassa | E. coli |
Bifunctional enzyme that possesses chorismate synthase and intrinsic flavin reductase activity, it uses NADPH to reduce FMN. | |||
TMPY-01736 | COX-2 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a perox... | |||
TMPJ-00520 | NANS Protein, Human, Recombinant (His) | Human | E. coli |
Sialic Acid Synthase (NANS) is an enzyme that contains one AFP-like domain. NANS is ubiquitous and plays a role in the biosynthetic pathways of sialic acids. NANS produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-de... | |||
TMPH-00040 | EPSP synthase Protein, Agrobacterium sp., Recombinant (His) | Agrobacterium sp. | HEK293 |
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | |||
TMPJ-00819 | Trp A Protein, E. coli, Recombinant | E.coli | E. coli |
Tryptophan synthase is an enzyme that catalyzes the final two steps in the biosynthesis of tryptophan. It is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from animals such as ... | |||
TMPJ-00820 | Trp B Protein, E. coli, Recombinant (His) | E.coli | E. coli |
Tryptophan synthase is an enzyme that catalyzes the final two steps in the biosynthesis of tryptophan. It is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from animals such as ... | |||
TMPH-01603 | Lanosterol synthase/LSS Protein, Human, Recombinant (His) | Human | E. coli |
Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens prote... | |||
TMPH-02477 | ALAS1 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
ALAS1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli with N-terminal 10xHis tag and C-terminal Myc tag. The predicted molecular weight is 72.3 kDa. Accession number: Q8VC19 | |||
TMPH-00041 | EPSP synthase Protein, Agrobacterium sp., Recombinant (His & SUMO) | Agrobacterium sp. | E. coli |
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | |||
TMPH-00566 | EPSP synthase Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | |||
TMPH-03189 | EPSP synthase Protein, Pseudomonas sp., Recombinant (His & Myc) | Pseudomonas sp. | E. coli |
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | |||
TMPH-00710 | PEP synthase Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. | |||
TMPY-01113 | SGMS2 Protein, Human, Recombinant (mFc) | Human | HEK293 |
SGMS2 Protein, Human, Recombinant (mFc) is expressed in HEK293 with mFc tag. The predicted molecular weight is 35.7 kDa. Accession number: A0A024RDH4 | |||
TMPY-03452 | PTS Protein, Human, Recombinant (His) | Human | E. coli |
PTS(6-pyruvoyltetrahydropterin synthase) belongs to the PTPS family. It catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesi... | |||
TMPJ-00982 | DHS Protein, Human, Recombinant (His) | Human | E. coli |
Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NAD-dependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine moiety of spermidine to... | |||
TMPY-02654 | FDPS Protein, Human, Recombinant (His) | Human | E. coli |
Z-farnesyl diphosphate synthase (FDPS) is an enzyme belonging to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. Z-farnesyl diphosphate synthase (FDPS) functions... | |||
TMPJ-00806 | HMBS Protein, Human, Recombinant (His) | Human | Human Cells |
Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hyd... | |||
TMPY-06686 | FASN Protein, Mouse, Recombinant (His) | Mouse | E. coli |
FASN Protein, Mouse, Recombinant (His) is expressed in E. coli with His tag. The predicted molecular weight is 34.23 kDa. Accession number: P19096 | |||
TMPH-01166 | CGAS Protein, Human, Recombinant (His) | Human | E. coli |
CGAS Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPY-01480 | LTC4S Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Leukotriene C4 synthase, also known as LTC4 synthase, Leukotriene-C(4) synthase, and LTC4S, is a multi-pass membrane protein that belongs to the MAPEG family. LTC4S is detected in the lung, platelets, and the myelogenous... | |||
TMPH-02530 | ATP5B Protein, Mouse, Recombinant (His & Myc & SUMO) | Mouse | E. coli |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respirator... | |||
TMPH-00017 | AcpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc) | Acholeplasma laidlawii | E. coli |
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. | |||
TMPH-00964 | ATP5PB Protein, Human, Recombinant (His & Myc) | Human | E. coli |
ATP5PB Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPY-00330 | GGPS1 Protein, Human, Recombinant (His) | Human | HEK293 |
GGPS1 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 36.3 kDa. Accession number: A0A024R3R2 | |||
TMPH-00967 | ATP5F1B Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
ATP5F1B Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli. | |||
TMPH-00664 | EPSP synthase Protein, E. coli O157:H7, Recombinant (His & Myc) | E. coli | E. coli |
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | |||
TMPH-03249 | ATP5F1B Protein, Rat, Recombinant (His & Myc) | Rat | E. coli |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respirator... | |||
TMPH-00966 | ATP5F1B Protein, Human, Recombinant (His) | Human | Yeast |
ATP5F1B Protein, Human, Recombinant (His) is expressed in Yeast. | |||
TMPH-00226 | ATPase subunit g Protein, Bovine, Recombinant (His & Myc) | Bovine | E. coli |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respirator... | |||
TMPJ-00732 | ASS1 Protein, Human, Recombinant (His) | Human | E. coli |
Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspart... | |||
TMPH-00965 | ATP5F1A Protein, Human, Recombinant (His) | Human | E. coli |
ATP5F1A Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-00969 | ATP5O Protein, Human, Recombinant (GST) | Human | E. coli |
ATP5O Protein, Human, Recombinant (GST) is expressed in E. coli. | |||
TMPH-00475 | DNA ligase Protein, Desulfotalea psychrophila, Recombinant (His) | Desulfotalea psychrophila | E. coli |
DNA ligase Protein, Desulfotalea psychrophila, Recombinant (His) is expressed in E. coli. | |||
TMPY-06683 | FASN Protein, Human, Recombinant (His) | Human | E. coli |
FASN Protein, Human, Recombinant (His) is expressed in E. coli with His tag. The predicted molecular weight is 35.26 kDa. Accession number: P49327 | |||
TMPH-00425 | DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His) | Colwellia psychrerythraea | E. coli |
DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His) is expressed in E. coli. | |||
TMPH-03596 | Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc) | Streptococcus pyogenes | Baculovirus |
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. | |||
TMPY-00451 | FDPS Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Z-farnesyl diphosphate synthase (FDPS) is an enzyme belonging to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. Z-farnesyl diphosphate synthase (FDPS) functions... | |||
TMPH-02993 | DisA Protein, Mycobacterium paratuberculosis, Recombinant (His & Myc) | Mycobacterium paratuberculosis | E. coli |
Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules int... | |||
TMPY-03609 | ATP5D Protein, Human, Recombinant (His) | Human | E. coli |
ATP5D is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synth... | |||
TMPH-02527 | ASS1 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate f... | |||
TMPH-00968 | ATP5C1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
ATP5C1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPJ-00979 | GSH-S Protein, Human, Recombinant (His) | Human | E. coli |
Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glyci... | |||
------------------------ More ------------------------ |
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A unique collection of 496 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS). | |||
L8000 | Stem Cell Differentiation Compound Library | 1213 compounds | |
A unique collection of 1213 stem cell differentiation signaling targeted compounds for high throughput and high content screening; |