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Search Results for " N-terminal "

ターゲット

JNK

176

阻害剤

天然化合物

225

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T9688	CC-90001		JNK
	CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over JNK2.		JNK
T34600	Secretin (1-6)	Secretin,N-terminal hexapeptide
	Secretin (1-6) is the N-terminal part of secretin. It can produce vitro glucose-dependent insulin release induced by secretin.
T83697	PAMP-12 (human, mouse, rat, porcine, bovine) TFA	Proadrenomedullin N-terminal 12 Peptide,PAMP (9-20)
	Proadrenomedullin N-terminal 12 peptide (PAMP-12), an endogenous fragment originating from the adrenal medulla and spanning amino acids 9-20 of human PAMP-20, plays a role in causing hypotension. It functions as an agoni...
TP1036	Sphistin Synthetic Peptide	Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide)
	Sphistin Synthetic Peptide is a truncated fragments of Sphistin Synthetic Peptide that shows potent antimicrobial activity.
T75957	Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide)
	Sphistin Synthetic Peptide (12-38, Fitc in N-Terminal-Fluorescently Labeled Peptide) represents truncated fragments of the parent Sphistin Synthetic Peptide, characterized by the presence of a fluorescent label (Fitc) at...
T19444	N-Biotinyl-6-aminohexanoic acid	N-(+)-Biotinyl-6-aminohexanoic acid	Others
	N-Biotinyl-6-aminohexanoic acid (N-(+)-Biotinyl-6-aminohexanoic acid) can be used to perform N-terminal biotinylation.		Others
T20482L	Acth (1-4) acetate(19405-50-6 free base)		Others
	Acth (1-4) acetate is the ACTH N-terminal tetrapeptide.		Others
TP1381L	HAEGT TFA(852155-81-8 free base)		Others
	HAEGT TFA is the first N-terminal 1-5 residues of GLP-1 peptide.		Others
TP1419L	HAEGTFT acetate(926018-95-3 free base)		Glucagon Receptor
	HAEGTFT acetate is the first N-terminal 1-7 residues of GLP-1 peptide.		Glucagon Receptor
T8931L	ICCB-19 hydrochloride	ICCB-19 HCl（750621-52-4 free base）	Apoptosis , Others , Autophagy , RIP kinase
	ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal dom...		Apoptosis , Others , Autophagy , RIP kinase
TP1382L	HAEGTFTSDVS acetate	HAEGTFTSDVS acetate(864915-61-7 free base)	Glucagon Receptor
	HAEGTFTSDVS acetate is the first N-terminal 1-11 residues of GLP-1 which stimulates insulin secretion from pancreatic β-cells.		Glucagon Receptor
T9584	UNC6934		Others , Histone Methyltransferase
	UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.		Others , Histone Methyltransferase
TP1508L	N-Acetyl-α-Endorphin acetate(88264-63-5 free base)		Others
	N-Acetyl-α-Endorphin acetate is an acetylated α-Endorphin at N-terminal. α-Endorphin is an endogenous opioid peptide.		Others
T9079	Apostatin-1	Apt-1	Others
	Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.		Others
T5885	N-Acetyl-D-galactosamine	GalNAc	Others
	N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans.		Others
T5833	CC-401 Hydrochloride	CC401 HCl	JNK
	CC-401 Hydrochloride (CC401 HCl) is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor (Ki of 25 to 50 nM.)with potential antineoplastic activity.		JNK
TP1031	Tetracosactide	Tetracosactrin	Others
	Tetracosactide (Tetracosactrin) (INN) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone.		Others
T13547L	AMP-PCP disodium		HSP
	AMP-PCP disodium is an ATP analogue with binding affinity to the N-terminal domain of Hsp90, with a Kd value of 3.8 μM. The binding of AMP-PCP disodium contributes to the formation of an active homodimer of Hsp90.		HSP
T10659	Ca2+ channel agonist 1		Calcium Channel , CDK
	Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction.		Calcium Channel , CDK
T5104	BTSA1		Apoptosis , BCL
	BTSA1 is a BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis.		Apoptosis , BCL
T20000	I-XW-053		HIV Protease
	I-XW-053 is a capsid targeted HIV-1 replication inhibitor.		HIV Protease
TP1696L	CGGRGD acetate(1260223-44-6 free base)		Others
	CGGRGD acetate is a RGD derivative with cysteine as the n-terminal. CGGRGD was synthesized by solid phase peptide synthesis technology, and amino2-cyanobenzothiazole (2-cyanobenzothiazole) (2-cyanobenzothiazole (CBT) was...		Others
T7677	JNK Inhibitor VIII	TCS JNK 6o	JNK
	JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively).		JNK
T36375	Ralaniten triacetate	EPI-506	Androgen Receptor
	Ralaniten triacetate (EPI-506), a precursor of Ralaniten, is a first-of-its-kind, orally active androgen receptor N-terminal structural domain (AR-NTD) inhibitor with anticancer activity and can be used to study prostate...		Androgen Receptor
T40711	H-D-Phe-Pip-Arg-pNA dihydrochloride	S-2238 dihydrochloride,H-D-Phe-Pip-Arg-pNA dihydrochloride	Others
	H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238 dihydrochloride), a chromogenic substrate, mimics the N-terminal fragment of the A alpha chain of fibrinogen, the native substrate of thrombin. Specifically designed for thromb...		Others
T28502	Ralaniten	EPI-002	Androgen Receptor
	Ralaniten (EPI-002) is a potent, specific, and orally active antagonist of the androgen receptor N-terminal structural domain (AR-NTD).Ralaniten inhibits AR transcriptional activity with an IC50 value of 7.4 μM.Ralanites...		Androgen Receptor
T35390	Magrolimab	Hu5F9-G4,Magrolimab (anti-CD47)	Others
	Magrolimab (Hu5F9-G4) is a humanized anti-CD47 IgG4 monoclonal antibody that exhibits its antitumor activity by blocking CD47 and binds primarily to the N-terminal pyroglutamate of CD47, and can be used in combination wi...		Others
T73133	FGF22-IN-1		Others
	FGF22-IN-1 is a potential CD4 N-terminal immunoglobulin variable region-like domain (CD4 D1) inhibitor.FGF22-IN-1 inhibits the interaction between CD4 and major histocompatibility complex (MHC) class II proteins and supp...		Others
TP1143L	Fibrinopeptide A, human acetate	Fibrinopeptide A, human acetate(25422-31-5 free base),Human fibrinopeptide A acetate	Others
	Fibrinopeptide A, human acetate (Human fibrinopeptide A acetate) is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A (FPA) is produced from the N-terminal Aα region of fibrinogen prote...		Others
TP1002L	γ-1-MSH, amide acetate (72629-65-3 free base)	γ-1-MSH, amide acetate	Others
	γ-1-MSH, amide acetate (72629-65-3 free base), a putative hormone in the N-terminal region of the ACTH/beta- endorphin (beta-EP) precursor protein, was studied by RIA with an antiserum against gamma 3-MSH in ACTH-produci...		Others
T21505	Suberoyl bis-hydroxamic acid	SBHA,Suberohydroxamic acid	Apoptosis , HDAC
	Suberoyl bis-hydroxamic acid (SBHA) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development. It is an enzyme that deacetylates lysine residues on ...		Apoptosis , HDAC
TQ0003L1	740 Y-P acetate	PDGFR 740Y-P Acetate,740YPDGFR acetate,740 Y-P acetate(1236188-16-1 Free base)	PI3K
	740 Y-P acetate (740YPDGFR acetate) is a potent and cell-permeable PI3K activator.740 Y-P acetate tends to bind to GST fusion proteins containing the N- and C-terminal SH2 structural domains of p85, but not to GST alone.		PI3K
T6829	EPI-001	EPI001,EPI 001	Apoptosis , Androgen Receptor , PPAR
	EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.		Apoptosis , Androgen Receptor , PPAR
TP1897L1	JIP-1 (153-163) acetate(438567-88-5 free base)		JNK
	JIP-1 (153-163) acetate(438567-88-5 free base) is a peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). JIP-1 (153-163) acetate(438567-88-5 free base) binds...		JNK
TP1559L	Ziconotide Acetate (107452-89-1 free base)	Prialt,Ziconotide Acetate	Calcium Channel
	Ziconotide Acetate (107452-89-1 free base) (Prialt) is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide Acetate (107452-89-1 free base) acts by binding to N-type calcium chan...		Calcium Channel
T14834	BT2		BCL
	BT2, a BCKDC kinase (BDK) inhibitor, exhibits an IC50 of 3.19 μM and functions as a potent, selective Mcl-1 inhibitor with a Ki value of 59 μM. Its interaction with BDK induces helix movements in the N-terminal domain, l...		BCL
T14091	AC-73		Autophagy
	AC-73 is an orally available Cluster of Differentiation 147 (CD147) inhibitor with high bioavailability that selectively disrupts the dimerization of CD147 (the binding site is in the N-terminal IgC2 domain of CD147 incl...		Autophagy
TP1280	Hexa-His		Others
	Hexa His is an amino acid sequence consisting of 6 His residues in a row, it is also known as hexa histidine-tag, 6xHis-tag, and by the trademarked name His-tag. Hexa His Responsible for the degradation of GM2 gangliosid...		Others
T3627	IQ-1S free acid	IQ-1,IQ-1S,IQ-1S (free acid)	NF-κB , JNK
	IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can se...		NF-κB , JNK
T1006	Propantheline bromide	Neopepulsan,Pro-Banthine,Neometantyl	AChR
	Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromid...		AChR
T34954	Tripalmitoyl cysteine	Tripalmitoyl-S-glyceryl cysteine
	Tripalmitoyl cysteine is a synthetic analog of the N-terminal lipid part of bacterial lipoprotein.
T34734	Substance P (1-4)	SP(1-4)
	Substance P (1-4) is a substance P N-terminal tetrapeptide fragment.
T32083	Histidylprolineamide	His-pro-amide
	Histidylprolineamide is the N-terminal of TRH.
T24830	SR-4326
	SR-4326 is a c-Jun N-terminal Kinase 3 inhibitor.
T32126	Hypusine
	Hypusine is an N-terminal amino alcohol derivative of Lys occurring in bovine brain &
T33552	N-(Azido-PEG3)-N-bis(PEG3-NHS ester)
	N-(Azido-PEG3)-N-bis(PEG3-NHS ester) is a branched PEG derivative with a terminal azide group and two terminal NHS esters. The azide group enables PEGylation via Click Chemistry. The NHS esters can be used to label the p...
T36767	Parathyroid Hormone (1-13) (trifluoroacetate salt)
	Parathyroid hormone (PTH) (1-13) is an N-terminal fragment of PTH (1-34) . In vivo, PTH (1-13) (0.003-1 μmol/kg) increases mean arterial pressure (MAP) in anesthetized rats.
T69527	Erioflorin
	Erioflorin is an ATP-competitive selective c-Jun N-terminal kinase (JNK) inhibitor.
TP1508	N-Acetyl-α-Endorphin
	N-Acetyl-α-Endorphin is a chemical compound consisting of α-Endorphin that has been acetylated at the N-terminal. α-Endorphin, in turn, is an endogenous opioid peptide.
T16173	N-(Amino-PEG5)-N-bis(PEG4-acid)		Others
	N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG-based PROTAC linker employed for synthesizing PROTACs. It comprises an amino group with two terminal carboxylic acids[1].		Others

Compounds

Synonym: Secretin,N-terminal hexapeptide

Target:

PAMP-12 (human, mouse, rat, porcine, bovine) TFA

T83697

Synonym: Proadrenomedullin N-terminal 12 Peptide,PAMP (9-20)

Target:

Sphistin Synthetic Peptide

TP1036

Synonym: Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide)

Target:

Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide)

T75957

Synonym:

Target:

N-Biotinyl-6-aminohexanoic acid

T19444

Synonym: N-(+)-Biotinyl-6-aminohexanoic acid

Target: Others

Acth (1-4) acetate(19405-50-6 free base)

T20482L

Synonym:

Target: Others

HAEGT TFA(852155-81-8 free base)

TP1381L

Synonym:

Target: Others

HAEGTFT acetate(926018-95-3 free base)

TP1419L

Synonym:

Target: Glucagon Receptor

ICCB-19 hydrochloride

T8931L

Synonym: ICCB-19 HCl（750621-52-4 free base）

Target: Apoptosis, Others, Autophagy, RIP kinase

HAEGTFTSDVS acetate

TP1382L

Synonym: HAEGTFTSDVS acetate(864915-61-7 free base)

Target: Glucagon Receptor

UNC6934

T9584

Synonym:

Target: Others, Histone Methyltransferase

N-Acetyl-α-Endorphin acetate(88264-63-5 free base)

N-Acetyl-D-galactosamine

Synonym: Tetracosactrin

Ca2+ channel agonist 1

T10659

Synonym:

Target: Calcium Channel, CDK

BTSA1

T5104

Synonym:

Target: Apoptosis, BCL

CGGRGD acetate(1260223-44-6 free base)

Target: Androgen Receptor

H-D-Phe-Pip-Arg-pNA dihydrochloride

T40711

Synonym: S-2238 dihydrochloride,H-D-Phe-Pip-Arg-pNA dihydrochloride

Target: Androgen Receptor

Magrolimab

T35390

Synonym: Hu5F9-G4,Magrolimab (anti-CD47)

Fibrinopeptide A, human acetate

TP1143L

Synonym: Fibrinopeptide A, human acetate(25422-31-5 free base),Human fibrinopeptide A acetate

Target: Others

γ-1-MSH, amide acetate (72629-65-3 free base)

TP1002L

Synonym: γ-1-MSH, amide acetate

Target: Others

Suberoyl bis-hydroxamic acid

T21505

Synonym: SBHA,Suberohydroxamic acid

Target: Apoptosis, HDAC

740 Y-P acetate

TQ0003L1

Synonym: PDGFR 740Y-P Acetate,740YPDGFR acetate,740 Y-P acetate(1236188-16-1 Free base)

Target: PI3K

EPI-001

T6829

Synonym: EPI001,EPI 001

Target: Apoptosis, Androgen Receptor, PPAR

JIP-1 (153-163) acetate(438567-88-5 free base)

TP1897L1

Synonym:

Target: JNK

Ziconotide Acetate (107452-89-1 free base)

TP1559L

Synonym: Prialt,Ziconotide Acetate

Target: Calcium Channel

Synonym: IQ-1,IQ-1S,IQ-1S (free acid)

Target: NF-κB, JNK

Propantheline bromide

T1006

Synonym: Neopepulsan,Pro-Banthine,Neometantyl

Target: AChR

Tripalmitoyl cysteine

T34954

Synonym: Tripalmitoyl-S-glyceryl cysteine

Synonym: His-pro-amide

N-(Azido-PEG3)-N-bis(PEG3-NHS ester)

T33552

Synonym:

Target:

Parathyroid Hormone (1-13) (trifluoroacetate salt)

N-(Amino-PEG5)-N-bis(PEG4-acid)

T16173

Synonym:

Target: Others

カタログ番号	製品名	別名	ターゲット
T0518	Methacycline hydrochloride	Rondomycin,Methacycline HCl	ribosome , Antibacterial , Antibiotic
	Methacycline hydrochloride (Rondomycin) is a broad-spectrum semisynthetic antibiotic related to TETRACYCLINE but excreted more slowly and maintaining effective blood levels for a more extended period.		ribosome , Antibacterial , Antibiotic
T3892	Isoacteoside	Isoverbascoside	NF-κB
	Isoacteoside has the anti-inflammatory effect, mediated by action on caspase-1, mitogen-activated protein kinases (c-Jun N-terminal kinase, p38, extracellular signal-regulated protein kinase) and nuclear factor-kappa B p...		NF-κB
T3908	10-Gingerol		Apoptosis
	10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase (JNK), and extracellular signal-regulated kinase (ERK).		Apoptosis
T3949	Myristic acid	Crodacid,Tetradecanoic acid,n-Tetradecanoic acid	Others , Endogenous Metabolite
	Myristic acid (Crodacid) , a 14 carbon saturated fatty acid, is a rare molecule in cells and is a substrate of some fatty acid desaturases. This compound has the ability to acylate proteins by covalently binding to the N...		Others , Endogenous Metabolite
T3391	Corosolic acid	Corsolic acid,2α-Hydroxyursolic acid,Glucosol,Colosolic acid,Colosic acid	FAK , Autophagy
	Corosolic acid (Colosic acid) contains anti-angiogenic activity that can suppress FAK signaling induced by angiopoietin-1. Corosolic acid exerts anticancer activities against HCC, colon, and colorectal Y cells, by induci...		FAK , Autophagy
T4757	L-Homoserine	(S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID	Others , Endogenous Metabolite
	L-Homoserine ((S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID) is a more reactive variant of the amino acid serine. In this variant, the hydroxyl side chain contains an additional CH2 group which brings the hydroxyl group closer t...		Others , Endogenous Metabolite
T6S1597	Mulberroside A		TNF , Tyrosinase , Interleukin
	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...		TNF , Tyrosinase , Interleukin
T6343	Geldanamycin	NSC 122750	HSP , Influenza Virus , Tyrosine Kinases , Antibacterial , Antibiotic
	Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.
T6S1572	Sauchinone		ERK , p38 MAPK , NF-κB
	1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative...		ERK , p38 MAPK , NF-κB
TN2360	Falcarinol	Falcarinol,Panaxynol	HSP
	Falcarinol, also known as Panaxynol, is a naturally occurring compound that acts as an orally active inhibitor of Hsp90. It effectively targets both the N-terminal and C-terminal regions of Hsp90, displaying high selecti...		HSP

天然物製品

Methacycline hydrochloride

T0518

Synonym: Rondomycin,Methacycline HCl

Target: ribosome, Antibacterial, Antibiotic

Isoacteoside

T3892

Synonym: Isoverbascoside

Synonym: Crodacid,Tetradecanoic acid,n-Tetradecanoic acid

Target: Others, Endogenous Metabolite

Corosolic acid

T3391

Synonym: Corsolic acid,2α-Hydroxyursolic acid,Glucosol,Colosolic acid,Colosic acid

Target: FAK, Autophagy

L-Homoserine

T4757

Synonym: (S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID

Target: Others, Endogenous Metabolite

Mulberroside A

T6S1597

Synonym:

Target: TNF, Tyrosinase, Interleukin

Geldanamycin

T6343

Synonym: NSC 122750

Target: HSP, Influenza Virus, Tyrosine Kinases, Antibacterial, Antibiotic

Sauchinone

T6S1572

Synonym:

Target: ERK, p38 MAPK, NF-κB

Falcarinol

TN2360

Synonym: Falcarinol,Panaxynol

Target: HSP

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-05028	NOTCH2NL Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	NOTCH2NLA (Notch 2 N-Terminal Like A) is a Protein Coding gene. NOTCH2NL, human-specific paralogs of the NOTCH2 receptor, stood out for their ability to promote cortical progenitor maintenance. It belongs to the NOTCH fa...
TMPJ-00489	NTAQ1 Protein, Human, Recombinant (GST)	Human	E. coli
	Human protein N-terminal glutamine amidohydrolase (WDYHV1) is an enzyme that in humans is encoded by the WDYHV1 gene, belongs to the NTAQ1 family.WDYHV1 mediates the side-chain deamidation of N-terminal glutamine residue...
TMPY-01285	METTL11A Protein, Human, Recombinant	Human	E. coli
	METTL11A Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 25.5 kDa and the accession number is A0A024R8E4.
TMPY-01284	METTL11A Protein, Human, Recombinant (GST)	Human	E. coli
	METTL11A Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 52.2 kDa and the accession number is A0A024R8E4.
TMPK-00156	DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi)	Human	HEK293 Cells
	Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 N termi...
TMPK-00158	DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	Dickkopf-1 (Dkk1), the founding and best-studied member of the Dkk family, functions as an antagonist of canonical Wnt/β-catenin. Dkk1 is considered to play a broad role in a variety of biological processes. DKK1 N termi...
TMPY-02580	Histone H1 Protein, Human, Recombinant (His)	Human	E. coli
	H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "...
TMPY-02707	PAH Protein, Human, Recombinant (415 Asn/Asp, His)	Human	Baculovirus Insect Cells
	PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding si...
TMPY-02700	BCL2 Protein, Human, Recombinant (His)	Human	E. coli
	BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a...
TMPY-03650	BirA Protein, E. coli, Recombinant (His & MBP)	E. coli	E. coli
	The enzyme BirA is a key reagent because of its ability to biotinylate proteins at a specific residue in a recognition sequence. This enzyme is used to biotinylate the C termini of membrane proteins, allowing these prote...
TMPY-04572	MKK4 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is...
TMPY-04830	GAS6 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ...
TMPJ-01011	FGF-9 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Fibroblast growth factor-9 (FGF-9) is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted mouse FGF-9 lacks the N-terminal 1-3 aa and shares >98% sequence identity with rat, human, equine, porcine a...
TMPH-00654	Methionine aminopeptidase Protein, E. coli, Recombinant (His & SUMO)	E. coli	E. coli
	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requ...
TMPH-01749	NAA38 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. NAA38 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression sy...
TMPH-00678	Peptide deformylase Protein, E. coli O157:H7, Recombinant (His & SUMO)	E. coli	E. coli
	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has b...
TMPH-00702	Peptide deformylase Protein, E. coli, Recombinant (His & SUMO)	E. coli	E. coli
	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has b...
TMPH-03029	MetAP Protein, Mycoplasma pneumoniae, Recombinant (His & SUMO)	Mycoplasma pneumoniae	E. coli
	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requ...
TMPH-02665	Aldolase C Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Aldolase C Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli with N-terminal 10xHis tag and C-terminal Myc tag. The predicted molecular weight is 46.7 kDa. Accession number: P05063
TMPH-00679	Peptide deformylase Protein, E. coli O157:H7, Recombinant (His)	E. coli	P. pastoris (Yeast)
	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has b...
TMPH-03566	Peptide deformylase Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	P. pastoris (Yeast)
	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has b...
TMPH-00590	GlmU Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine...
TMPH-00513	Proline iminopeptidase Protein, Elizabethkingia meningoseptica, Recombinant (His & Myc)	Elizabethkingia meningoseptica	E. coli
	Releases the N-terminal proline from various substrates. Cleaves specifically Pro-betaNA and small peptides containing proline at the amino terminal. No activity against hydroxyproline-betaNA. Proline iminopeptidase Prot...
TMPH-03018	MeTAP1 Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	E. coli
	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requ...
TMPH-02689	Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli with N-terminal 10xHis tag and C-terminal Myc tag. The predicted molecular weight is 33.9 kDa. Accession number: O35205
TMPH-03567	Peptide deformylase Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has b...
TMPH-00701	PBP1b Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-...
TMPJ-00313	Fumarase Protein, Human, Recombinant	Human	E. coli
	Fumarase is an enzyme that catalyze the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid or Krebs cycle. Fumarase exists in both form, cytosolic formand N-terminal extend...
TMPH-03044	PBP1a Protein, MenB, Recombinant (His & SUMO)	MenB	E. coli
	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-...
TMPH-03248	ASGR1 Protein, Rat, Recombinant (His & Myc)	Rat	HEK293 Cells
	Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine uni...
TMPH-00888	APEH Protein, Human, Recombinant (His)	Human	E. coli
	This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and...
TMPJ-01092	MGAT2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal...
TMPK-00895	Tubby Protein, Human, Recombinant (His)	Human	E. coli
	Tubby is the founding member of the tubby-like family of proteins. Tubby-like proteins (TLPs) possess a highly conserved closed β barrel tubby domain at C-terminal and N-terminal F-box.Tubby plays a critical role in traf...
TMPH-01340	Filaggrin Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis. Filaggrin Protein, Human, Recombinant (His) is expr...
TMPH-03117	IL-5 Protein, Pig, Recombinant (E. coli, His)	Sus scrofa (Pig)	E. coli
	Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. IL-5 Protein, Pig, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The pre...
TMPY-02430	BCL6 Protein, Human, Recombinant (aa 1-150, His & Trx)	Human	E. coli
	The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported that BCL-6 is present in DNA-binding complexe...
TMPH-03032	Leucyl aminopeptidase Protein, Mycoplasma pneumoniae, Recombinant (His & SUMO)	Mycoplasma pneumoniae	E. coli
	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. Leucyl aminopeptidase Protein, Mycoplasma pneumon...
TMPJ-01364	LMCD1 Protein, Human, Recombinant (His)	Human	E. coli
	LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a ...
TMPH-02174	PYCR1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	PYCR1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli with N-terminal 6xHis-SUMO tag. The predicted molecular weight is 33.7 kDa. Accession number: Q8TBX0
TMPH-02529	ASGR2 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine uni...
TMPH-01266	RNF13 Protein, Human, Recombinant (His)	Human	E. coli
	RNF13 Protein, Human, Recombinant (His) is expressed in E. coli with N-terminal 10xHis tag. The predicted molecular weight is 26.2 kDa. Accession number: O43567
TMPH-02289	FAU Protein, Human, Recombinant (GST)	Human	E. coli
	FAU Protein, Human, Recombinant (GST) is expressed in E. coli with N-terminal GST tag. The predicted molecular weight is 41.4 kDa. Accession number: NM_001997
TMPH-00170	PBP 4 Protein, Bacillus subtilis, Recombinant (His & SUMO)	Bacillus subtilis	E. coli
	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-...
TMPH-00019	BlaNDM-1 Protein, Acinetobacter baumannii, Recombinant (His & SUMO)	Acinetobacter baumannii	E. coli
	BlaNDM-1 Protein, Acinetobacter baumannii, Recombinant (His & SUMO) is expressed in E. coli with N-terminal 6xHis-SUMO tag. The predicted molecular weight is 22.0 kDa. Accession number: F8UNN7
TMPH-00398	PPK2 Protein, Chlorobium tepidum, Recombinant (His & Myc)	Chlorobaculum tepidum	E. coli
	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). PPK2 Protein, Chlorobium tepidum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10...
TMPH-03118	IL-5 Protein, Pig, Recombinant (His)	Sus scrofa (Pig)	P. pastoris (Yeast)
	Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. IL-5 Protein, Pig, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 15...
TMPY-01953	CALML5 Protein, Human, Recombinant (His & GST)	Human	E. coli
	Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains fourEF-hand domains. CALML5 / CLSP is particularly abundant in the epidermis where its expression is ...
TMPH-03763	Major egg antigen Protein, Schistosoma mansoni, Recombinant (His)	Schistosoma mansoni	E. coli
	Major egg antigen Protein, Schistosoma mansoni, Recombinant (His) is expressed in E. coli with N-terminal 6xHis tag. The predicted molecular weight is 43.4 kDa. Accession number: P12812
TMPJ-00888	ANXA7 Protein, Human, Recombinant	Human	E. coli
	Annexin A7 (ANXA7) is a member of the annexin family of calcium-dependent phospholipid binding proteins. Annexin A7 has a unique, highly hydrophobic N-terminal domain and a conserved C-terminal region. The C-terminal reg...
TMPJ-00354	FZD1/Frizzled 1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Frizzled homolog 1 (FZD1), also known as Frizzled-1, a member of the G-protein-coupled receptor superfamily, mediates Wnt signaling by serving as a co-receptor with LRP-5 for Wnt ligands. The FZD1 protein contains a sign...
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NOTCH2NL Protein, Human, Recombinant (mFc)

TMPY-05028

Species: Human

Expression System: HEK293 Cells

NTAQ1 Protein, Human, Recombinant (GST)

TMPJ-00489

Species: Human

Expression System: E. coli

METTL11A Protein, Human, Recombinant

TMPY-01285

Species: Human

Expression System: E. coli

METTL11A Protein, Human, Recombinant (GST)

TMPY-01284

Species: Human

Expression System: E. coli

DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi)

TMPK-00156

Species: Human

Expression System: HEK293 Cells

DKK1 N terminal Domain Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPK-00158

Species: Human

Expression System: HEK293 Cells

Histone H1 Protein, Human, Recombinant (His)

TMPY-02580

Species: Human

Expression System: E. coli

PAH Protein, Human, Recombinant (415 Asn/Asp, His)

TMPY-02707

Species: Human

Expression System: Baculovirus Insect Cells

BCL2 Protein, Human, Recombinant (His)

TMPY-02700

Species: Human

Expression System: E. coli

BirA Protein, E. coli, Recombinant (His & MBP)

TMPY-03650

Species: E. coli

Expression System: E. coli

MKK4 Protein, Mouse, Recombinant (His & GST)

TMPY-04572

Species: Mouse

Expression System: Baculovirus Insect Cells

GAS6 Protein, Mouse, Recombinant (His)

TMPY-04830

Species: Mouse

Expression System: HEK293 Cells

FGF-9 Protein, Mouse, Recombinant (His)

TMPJ-01011

Species: Mouse

Expression System: E. coli

Methionine aminopeptidase Protein, E. coli, Recombinant (His & SUMO)

TMPH-00654

Species: E. coli

Expression System: E. coli

NAA38 Protein, Human, Recombinant (His & SUMO)

TMPH-01749

Species: Human

Expression System: E. coli

Peptide deformylase Protein, E. coli O157:H7, Recombinant (His & SUMO)

TMPH-00678

Species: E. coli

Expression System: E. coli

Peptide deformylase Protein, E. coli, Recombinant (His & SUMO)

TMPH-00702

Species: E. coli

Expression System: E. coli

MetAP Protein, Mycoplasma pneumoniae, Recombinant (His & SUMO)

TMPH-03029

Species: Mycoplasma pneumoniae

Expression System: E. coli

Aldolase C Protein, Mouse, Recombinant (His & Myc)

TMPH-02665

Species: Mouse

Expression System: E. coli

Peptide deformylase Protein, E. coli O157:H7, Recombinant (His)

TMPH-00679

Species: E. coli

Expression System: P. pastoris (Yeast)

Peptide deformylase Protein, S. aureus, Recombinant (His)

TMPH-03566

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

GlmU Protein, E. coli, Recombinant (His & Myc)

TMPH-00590

Species: E. coli

Expression System: E. coli

Proline iminopeptidase Protein, Elizabethkingia meningoseptica, Recombinant (His & Myc)

TMPH-00513

Species: Elizabethkingia meningoseptica

Expression System: E. coli

MeTAP1 Protein, Mycobacterium tuberculosis, Recombinant (His)

TMPH-03018

Species: Mycobacterium tuberculosis

Expression System: E. coli

Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc)

TMPH-02689

Species: Mouse

Expression System: E. coli

Peptide deformylase Protein, S. aureus, Recombinant (His & SUMO)

TMPH-03567

Species: Staphylococcus aureus

Expression System: E. coli

PBP1b Protein, E. coli, Recombinant (His & Myc)

TMPH-00701

Species: E. coli

Expression System: E. coli

Fumarase Protein, Human, Recombinant

TMPJ-00313

Species: Human

Expression System: E. coli

PBP1a Protein, MenB, Recombinant (His & SUMO)

TMPH-03044

Species: MenB

Expression System: E. coli

ASGR1 Protein, Rat, Recombinant (His & Myc)

TMPH-03248

Species: Rat

Expression System: HEK293 Cells

APEH Protein, Human, Recombinant (His)

TMPH-00888

Species: Human

Expression System: E. coli

MGAT2 Protein, Human, Recombinant (His)

TMPJ-01092

Species: Human

Expression System: HEK293 Cells

Tubby Protein, Human, Recombinant (His)

TMPK-00895

Species: Human

Expression System: E. coli

Filaggrin Protein, Human, Recombinant (His)

TMPH-01340

Species: Human

Expression System: P. pastoris (Yeast)

IL-5 Protein, Pig, Recombinant (E. coli, His)

TMPH-03117

Species: Sus scrofa (Pig)

Expression System: E. coli

BCL6 Protein, Human, Recombinant (aa 1-150, His & Trx)

TMPY-02430

Species: Human

Expression System: E. coli

Leucyl aminopeptidase Protein, Mycoplasma pneumoniae, Recombinant (His & SUMO)

TMPH-03032

Species: Mycoplasma pneumoniae

Expression System: E. coli

LMCD1 Protein, Human, Recombinant (His)

TMPJ-01364

Species: Human

Expression System: E. coli

PYCR1 Protein, Human, Recombinant (His & SUMO)

TMPH-02174

Species: Human

Expression System: E. coli

ASGR2 Protein, Mouse, Recombinant (His & Myc)

TMPH-02529

Species: Mouse

Expression System: E. coli

RNF13 Protein, Human, Recombinant (His)

TMPH-01266

Species: Human

Expression System: E. coli

FAU Protein, Human, Recombinant (GST)

TMPH-02289

Species: Human

Expression System: E. coli

PBP 4 Protein, Bacillus subtilis, Recombinant (His & SUMO)

TMPH-00170

Species: Bacillus subtilis

Expression System: E. coli

BlaNDM-1 Protein, Acinetobacter baumannii, Recombinant (His & SUMO)

TMPH-00019

Species: Acinetobacter baumannii

Expression System: E. coli

PPK2 Protein, Chlorobium tepidum, Recombinant (His & Myc)

TMPH-00398

Species: Chlorobaculum tepidum

Expression System: E. coli

IL-5 Protein, Pig, Recombinant (His)

TMPH-03118

Species: Sus scrofa (Pig)

Expression System: P. pastoris (Yeast)

CALML5 Protein, Human, Recombinant (His & GST)

TMPY-01953

Species: Human

Expression System: E. coli

Major egg antigen Protein, Schistosoma mansoni, Recombinant (His)

TMPH-03763

Species: Schistosoma mansoni

Expression System: E. coli

ANXA7 Protein, Human, Recombinant

TMPJ-00888

Species: Human

Expression System: E. coli

FZD1/Frizzled 1 Protein, Mouse, Recombinant (hFc)

TMPJ-00354

Species: Mouse

Expression System: HEK293 Cells

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カタログ番号	製品名
L3510	Methylation Compound Library	128 compounds
	xnum methylation-related compounds that can be used for high-throughput and high-content screening.
L8720	Pyroptosis Compound Library	1066 compounds
	xnum types of active small molecules associated with pyroptosis for high-throughput and high-content screening.

ライブラリー

Methylation Compound Library

L3510

Compounds: 128

Pyroptosis Compound Library

L8720

Compounds: 1066