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Search Results for " Thyroid "

ターゲット

Thyroid hormone receptor(THR) TSH Receptor

阻害剤

天然化合物

116

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T12073	ML-109		TSH Receptor
	ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)		TSH Receptor
T9111	8-Azaadenosine		Adenosine deaminase
	8-Azaadenosine, a powerful ADAR1 (ADAR1) and A-to-I editing inhibitor, effectively blocks RNA editing and suppresses proliferation, 3D growth, invasion, and migration in thyroid cancer cells.		Adenosine deaminase
T2282	RPI-1		Others , Phospholipase , c-Met/HGFR , c-RET
	RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor.		Others , Phospholipase , c-Met/HGFR , c-RET
T8843	APS6-45		MAPK , Ras
	APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.		MAPK , Ras
T5360	Eprotirome	KB2115	Thyroid hormone receptor(THR)
	Eprotirome (KB2115), a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.		Thyroid hormone receptor(THR)
T40548	NH-3		Thyroid hormone receptor(THR)
	NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the selective thyromi-metic GC-1, NH-3 effectively inhibits the...		Thyroid hormone receptor(THR)
T1604	Tiratricol	3,3',5-Triiodothyroacetic acid	Thyroid hormone receptor(THR)
	Tiratricol (3,3',5-Triiodothyroacetic acid) is a metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of A...		Thyroid hormone receptor(THR)
T12192	NCGC00229600		Others , TSH Receptor
	NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies.		Others , TSH Receptor
T13072	Taltirelin acetate	TA-0910 acetate	Thyroid hormone receptor(THR)
	Taltirelin acetate (TA-0910 acetate) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release)).		Thyroid hormone receptor(THR)
T15012	Crolibulin	EPC2407	Microtubule Associated
	Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.		Microtubule Associated
T5383	D3-βArr	NCGC00379308	TSH Receptor
	D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.		TSH Receptor
T3595	Resmetirom	VIA-3196,MGL3196	Thyroid hormone receptor(THR)
	Resmetirom (VIA-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist.		Thyroid hormone receptor(THR)
T1669	Liothyronine sodium	3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,Sodium L-3,3',5-triiodothyronine,Cytomel	Thyroid hormone receptor(THR)
	Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine s...		Thyroid hormone receptor(THR)
T5313	Sobetirome	IACS-010759,QRX-431	Thyroid hormone receptor(THR)
	Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).		Thyroid hormone receptor(THR)
T13492	3,5-Diiodothyropropionic acid	C082182,Ditpa cpd	Thyroid hormone receptor(THR)
	3,5-Diiodothyropropionic acid (C082182) is a thyroid hormone analog. It induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (Ka: 2.40/M and 4.06/M for TRα1 and TRβ1).		Thyroid hormone receptor(THR)
T7578	REVERSE T3	3,3',5'-triiodo-L-thyronine	Thyroid hormone receptor(THR)
	Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.		Thyroid hormone receptor(THR)
TP1022	Protirelin Acetate	TSH-RF Acetate,TRH Acetate,TRF Acetate	Thyroid hormone receptor(THR) , Endogenous Metabolite
	Protirelin Acetate (TRH Acetate) is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary.		Thyroid hormone receptor(THR) , Endogenous Metabolite
T21505	Suberoyl bis-hydroxamic acid	SBHA,Suberohydroxamic acid	Apoptosis , HDAC
	Suberoyl bis-hydroxamic acid (SBHA) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development. It is an enzyme that deacetylates lysine residues on ...		Apoptosis , HDAC
T22355	L-Thyroxine sodium	LT4 sodium,Levothyroxine sodium,L-T4 sodium	Thyroid hormone receptor(THR)
	L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.		Thyroid hormone receptor(THR)
T1826	PI3K-IN-1	Voxtalisib Analogue,Voxtalisib (SAR245409, XL765) Analogue,XL765,SAR245409	DNA-PK , PI3K
	PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.		DNA-PK , PI3K
T7590	Taltirelin	TA-0910	Thyroid hormone receptor(THR)
	Taltirelin (TA-0910) is at thyrotropin-releasing hormone receptor (TRH-R) superagonist (IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release))[1].		Thyroid hormone receptor(THR)
T15699	L-Thyroxine sodium salt pentahydrate	Sodium levothyroxine pentahydrate,Levothyroxine	Thyroid hormone receptor(THR)
	L-Thyroxine sodium salt pentahydrate, also known as Levothyroxine, is a synthetic hormone utilized in the study of hypothyroidism. It is biologically activated into Triiodothyronine (T3) from its original form, L-Thyroxi...		Thyroid hormone receptor(THR)
T21535	Parathyroid Hormone (1-34), bovine		Thyroid hormone receptor(THR)
	Parathyroid Hormone (1-34), bovine is a parathyroid hormone (PTH) receptor agonist that is part of the parathyroid hormone family. Parathyroid Hormone (1-34), bovine is used to study osteoporosis and hypoparathyroidism.		Thyroid hormone receptor(THR)
T36767	Parathyroid Hormone (1-13) (trifluoroacetate salt)
	Parathyroid hormone (PTH) (1-13) is an N-terminal fragment of PTH (1-34) . In vivo, PTH (1-13) (0.003-1 μmol/kg) increases mean arterial pressure (MAP) in anesthetized rats.
TP2283	Parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]		Others
	parathyroid hormone (7-34) [Homo sapiens] [Macaca fascicularis] is a peptide with the sequence H2N-LMHNLGKHLNSMERVEWLRKKLQDVHNF-OH, MW= 3474.03. Parathyroid hormone (PTH) is secreted by the chief cells of the parathyroid...		Others
T75867	Parathyroid Hormone (1-34), bovine TFA
	Parathyroid Hormone (1-34), bovine TFA, a potent agonist of the parathyroid hormone (PTH) receptor, elevates calcium and inorganic phosphate levels in vivo. This compound is employed in osteoporosis research [1].
T76061	Parathyroid hormone (1-34) (rat) acetate
	Parathyroid hormone (1-34) (rat) (acetate) is a parathyroid hormone variant that enhances the structure of both cortical and cancellous bones. It is utilized in osteoporosis research [1] [2].
TP1964	Parathyroid hormone (1-34) (rat)
	Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats.
T76084	Parathyroid Hormone (1-34), human, biotinylated
	Parathyroid Hormone (1-34), human, biotinylated serves as a probe targeting the parathyroid hormone receptor. It is utilized in the analysis of interactions between parathyroid hormone and its receptors within living cel...
T73692	Parathyroid hormone
	Parathyroid hormone (PTH), an 84-amino acid circulating hormone synthesized in the parathyroid glands, primarily regulates bone and kidney functions to maintain extracellular calcium levels within normal ranges. It is al...
T2588	Ivacaftor	Ivacaftor (VX-770),VX-770	CFTR , Autophagy
	Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells, respectively.		CFTR , Autophagy
T13435	TR antagonist 1		Thyroid hormone receptor(THR)
	TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist (IC50 of 36 and 22 nM for TRα and TRβ, respectively) that can be used to study diseases caused by endocrine abnormalities.		Thyroid hormone receptor(THR)
T27454	GSK2008607		Raf
	GSK2008607 is a potent B-RafV600E inhibitor with anticancer activity and can be used to study breast, colorectal, melanoma, thyroid, and ovarian cancers.		Raf
T8672	2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE	BisOPP-A	Thyroid hormone receptor(THR)
	2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE is targets the thyroid stimulating hormone receptor (human)		Thyroid hormone receptor(THR)
T23673	AH-3960	AH3960	Thyroid hormone receptor(THR)
	AH-3960 is an thyroid hormone receptor-1 (PTHR1) agonist.		Thyroid hormone receptor(THR)
T1309	Propylthiouracil	Pseudocapsaicin,NSC 6498,NSC 70461,6-n-Propylthiouracil,6-Propyl-2-thiouracil	Thyroid hormone receptor(THR)
	Propylthiouracil (6-n-Propylthiouracil) is a thyroid peroxidase inhibitor and also a 5' -deiodinase inhibitor.		Thyroid hormone receptor(THR)
TP1028L	Calcitonin eel acetate	Calcitonin eel acetate (57014-02-5 Free base),Thyrocalcitonin eel	Others
	Calcitonin eel acetate (Calcitonin eel acetate (57014-02-5 Free base)) is the regulation of calcium homeostasis thyroid hormone peptide.		Others
T7407	Thyrotropin-Releasing Hormone (TRH), Free Acid	TRH-OH	Others
	Thyrotropin-Releasing Hormone (TRH), Free Acid (TRH-OH) (TRH-OH) causes a variety of thyroidal and non-thyroidal effects, the best known being the feedback regulation of thyroid hormone levels.		Others
T19561	Simetryn		Others
	Simetryn is a rice paddy herbicide and acts as a chemical stressor retarding tadpole growth and development without disrupting thyroid functions, even at 1/100 of the 96-h LC50 value.		Others
T0495	Aminothiazole	2-Aminothiazole,2-Thiazolylamine	Virus Protease , Antibacterial , Antibiotic , Antifungal
	Aminothiazole (2-Aminothiazole), a thyroid inhibitor, displays antibacterial activity.		Virus Protease , Antibacterial , Antibiotic , Antifungal
T0304	Methylthiouracil	NSC-193526,NSC-9378,MTU	ERK , Antiviral , TNF , NF-κB , Interleukin
	Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.		ERK , Antiviral , TNF , NF-κB , Interleukin
T9901A-004	Labetuzumab	IMMU-14,hMN-14,IMMU-100
	Labetuzumab is a humanized anti-carcinoembryonic antigen (CEA) monoclonal antibody with anticancer activity that inhibits tumor growth and is used in the study of thyroid and colorectal cancer (CRC).
T8628	2,4,6-Triiodophenol		Others
	2,4,6-Triiodophenol is used as an iodinated disinfection by product formed during chlorination of sewage effluents. It is also used as a potent thyroid disrupting chemical and to investigate deiodinase		Others
T0952	Carbimazole	Athyromazole,Carbimazol,Neomercazole	Thyroid hormone receptor(THR)
	Carbimazole (Athyromazole) is an Imidazolium thyroid antagonist, which is rapidly transformed into MMI in vivo and can be converted into methidazole in vitro, and can be used in the study of Graves' disease.		Thyroid hormone receptor(THR)
T0312	Toluidine Blue	Blutene chloride	Others
	Toluidine Blue (Blutene chloride), a phenothiazine, is used as a biological stain, a hemostatic, and a dye for silk and wool. Blutene chloride is also used as a diagnostic aid for gastric neoplasms and oral, and used in ...		Others
T77075	Spartalizumab	PDR001	PD-1/PD-L1
	Spartalizumab (PDR001) is a humanized immunoglobulin 4 monoclonal antibody that selectively binds to PD-1 at low concentrations and shows high activity. Spartalizumab blocks the interaction with PD-L1 and PD-L2, and can ...		PD-1/PD-L1
T76727	Teprotumumab	R 1507,HZN 001	TSH Receptor , IGF-1R
	Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular α-subunit domain ligand of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Te...		TSH Receptor , IGF-1R
T2595	Lumacaftor	VX-809,VRT 826809	CFTR , Autophagy
	Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM).		CFTR , Autophagy
T36493	CMLD-2		Apoptosis , HuR
	CMLD-2 is an inhibitor of HuR-ARE interaction (Ki: 350 nM) that competitively binds HuR protein and disrupts its interaction with adenine element-rich (ARE) mRNA targets.CMLD-2 induces apoptosis and exhibits antitumor ef...		Apoptosis , HuR
T1669L	Liothyronine HCl	Triiodothyronine,L-T3,NSC 80203,Liothyronine,Liotironina,L-Liothyronine
	Liothyronine is a T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine.

Compounds

Target: Adenosine deaminase

RPI-1

T2282

Synonym:

Target: Others, Phospholipase, c-Met/HGFR, c-RET

Target: Thyroid hormone receptor(THR)

NH-3

T40548

Synonym:

Target: Thyroid hormone receptor(THR)

Tiratricol

T1604

Synonym: 3,3',5-Triiodothyroacetic acid

Target: Thyroid hormone receptor(THR)

NCGC00229600

T12192

Synonym:

Target: Others, TSH Receptor

Taltirelin acetate

T13072

Synonym: TA-0910 acetate

Target: Thyroid hormone receptor(THR)

Crolibulin

T15012

Synonym: EPC2407

Target: Microtubule Associated

D3-βArr

T5383

Synonym: NCGC00379308

Target: TSH Receptor

Resmetirom

T3595

Synonym: VIA-3196,MGL3196

Target: Thyroid hormone receptor(THR)

Liothyronine sodium

T1669

Synonym: 3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,Sodium L-3,3',5-triiodothyronine,Cytomel

Target: Thyroid hormone receptor(THR)

Sobetirome

T5313

Synonym: IACS-010759,QRX-431

Target: Thyroid hormone receptor(THR)

3,5-Diiodothyropropionic acid

T13492

Synonym: C082182,Ditpa cpd

Target: Thyroid hormone receptor(THR)

REVERSE T3

T7578

Synonym: 3,3',5'-triiodo-L-thyronine

Target: Thyroid hormone receptor(THR)

Protirelin Acetate

TP1022

Synonym: TSH-RF Acetate,TRH Acetate,TRF Acetate

Target: Thyroid hormone receptor(THR), Endogenous Metabolite

Suberoyl bis-hydroxamic acid

T21505

Synonym: SBHA,Suberohydroxamic acid

Target: Apoptosis, HDAC

L-Thyroxine sodium

T22355

Synonym: LT4 sodium,Levothyroxine sodium,L-T4 sodium

Target: Thyroid hormone receptor(THR)

PI3K-IN-1

T1826

Synonym: Voxtalisib Analogue,Voxtalisib (SAR245409, XL765) Analogue,XL765,SAR245409

Target: Thyroid hormone receptor(THR)

L-Thyroxine sodium salt pentahydrate

T15699

Synonym: Sodium levothyroxine pentahydrate,Levothyroxine

Target: Thyroid hormone receptor(THR)

Parathyroid Hormone (1-34), bovine

T21535

Synonym:

Target: Thyroid hormone receptor(THR)

Parathyroid Hormone (1-13) (trifluoroacetate salt)

T36767

Synonym:

Target:

parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]

TP2283

Synonym:

Target: Others

Parathyroid Hormone (1-34), bovine TFA

T75867

Synonym:

Target:

Parathyroid hormone (1-34) (rat) acetate

T76061

Synonym:

Target:

Parathyroid hormone (1-34) (rat)

TP1964

Synonym:

Target:

Parathyroid Hormone (1-34), human, biotinylated

Synonym: Ivacaftor (VX-770),VX-770

Target: CFTR, Autophagy

TR antagonist 1

T13435

Synonym:

Target: Thyroid hormone receptor(THR)

2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE

T8672

Synonym: BisOPP-A

Target: Thyroid hormone receptor(THR)

AH-3960

T23673

Synonym: AH3960

Target: Thyroid hormone receptor(THR)

Propylthiouracil

T1309

Synonym: Pseudocapsaicin,NSC 6498,NSC 70461,6-n-Propylthiouracil,6-Propyl-2-thiouracil

Target: Thyroid hormone receptor(THR)

Calcitonin eel acetate

TP1028L

Synonym: Calcitonin eel acetate (57014-02-5 Free base),Thyrocalcitonin eel

Target: Others

Thyrotropin-Releasing Hormone (TRH), Free Acid

Synonym: 2-Aminothiazole,2-Thiazolylamine

Target: Virus Protease, Antibacterial, Antibiotic, Antifungal

Methylthiouracil

T0304

Synonym: NSC-193526,NSC-9378,MTU

Target: ERK, Antiviral, TNF, NF-κB, Interleukin

Labetuzumab

T9901A-004

Synonym: IMMU-14,hMN-14,IMMU-100

Synonym: Athyromazole,Carbimazol,Neomercazole

Target: Thyroid hormone receptor(THR)

Toluidine Blue

T0312

Synonym: Blutene chloride

Synonym: R 1507,HZN 001

Target: TSH Receptor, IGF-1R

Lumacaftor

T2595

Synonym: VX-809,VRT 826809

Target: CFTR, Autophagy

CMLD-2

T36493

Synonym:

Target: Apoptosis, HuR

Liothyronine HCl

T1669L

Synonym: Triiodothyronine,L-T3,NSC 80203,Liothyronine,Liotironina,L-Liothyronine

Target:

カタログ番号	製品名	別名	ターゲット
T5568	H-Tyr(3-I)-OH	3-Iodo-L-tyrosine	Endogenous Metabolite
	H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones		Endogenous Metabolite
T1653	Liothyronine	Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,Triiodothyronine,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine	Thyroid hormone receptor(THR) , Endogenous Metabolite
	Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.		Thyroid hormone receptor(THR) , Endogenous Metabolite
T0864	L-Thyroxine	Levothyroxine,NSC 36397,T4	Thyroid hormone receptor(THR) , Endogenous Metabolite
	L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in...		Thyroid hormone receptor(THR) , Endogenous Metabolite
T2988	(-)-Epigallocatechin Gallate	Epigallocatechol Gallate,EGCG	Ferroptosis , Reactive Oxygen Species , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite , Autophagy
	(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate (EGCG) blocks the activation of EGF receptors and HER-2 receptor...
T6956	Protirelin	Lopremone,pGlu-His-Pro-NH2,Synthetic thyrotropin-releasing hormone,Thyroliberin,TRH,TRF	Thyroid hormone receptor(THR) , Endogenous Metabolite
	Protirelin (Thyroliberin) is a tripeptide that stimulates the release of thyrotropin and prolactin.		Thyroid hormone receptor(THR) , Endogenous Metabolite
T16442	PCO371	2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-	Thyroid hormone receptor(THR)
	PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormon...		Thyroid hormone receptor(THR)
T2760	(S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate	Iodogorgoic acid,apothyrin,jodgorgon,3,5-Diiodotyrosine Dihydrate	Others , Endogenous Metabolite
	(S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate (jodgorgon) is a product from the iodination of MONOIODOTYROSINE. In the biosynthesis of thyroid hormones, diiodotyrosine residues are coupled with other...		Others , Endogenous Metabolite
T3665	Tectoridin	Shekanin	Estrogen Receptor/ERR , Reductase
	Tectoridin (Shekanin) possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflammatory and hypoglycemic activities; Tectoridin an...		Estrogen Receptor/ERR , Reductase
TN6798	Progoitrin		Others
	Progoitrin is a biochemical from the glucosinolate family that is found in some food, which is inactive but after ingestion is converted to goitrin. Goitrin decreases the thyroid hormone production. Apart from goitrin, p...		Others
T39836	Monoethyl phthalate
	Monoethyl phthalate is a metabolite of diethyl phthalate, serving as a urinary biomarker for phthalate exposure, and indicating potential risks of thyroid cancer and benign nodules.
T73465	Goitrin	L-5-Vinyl-2-thiooxazolidone,(S)-Goitrin,(S)-Goitrin ; L-5-Vinyl-2-thiooxazolidone
	Goitrin ((S)-Goitrin), formed through glucosinolate-myrosinase reactions, serves as a potent inhibitor of thyroid peroxidase, thereby hindering the thyroid's utilization of iodine. Additionally, it demonstrates anti-infl...

天然物製品

H-Tyr(3-I)-OH

T5568

Synonym: 3-Iodo-L-tyrosine

Target: Endogenous Metabolite

Liothyronine

T1653

Synonym: Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,Triiodothyronine,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine

Target: Thyroid hormone receptor(THR), Endogenous Metabolite

L-Thyroxine

T0864

Synonym: Levothyroxine,NSC 36397,T4

Target: Thyroid hormone receptor(THR), Endogenous Metabolite

(-)-Epigallocatechin Gallate

T2988

Synonym: Epigallocatechol Gallate,EGCG

Target: Ferroptosis, Reactive Oxygen Species, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite, Autophagy

Protirelin

T6956

Synonym: Lopremone,pGlu-His-Pro-NH2,Synthetic thyrotropin-releasing hormone,Thyroliberin,TRH,TRF

Target: Thyroid hormone receptor(THR), Endogenous Metabolite

PCO371

T16442

Synonym: 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-

Target: Thyroid hormone receptor(THR)

(S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate

T2760

Synonym: Iodogorgoic acid,apothyrin,jodgorgon,3,5-Diiodotyrosine Dihydrate

Target: Others, Endogenous Metabolite

Tectoridin

T3665

Synonym: Shekanin

Target: Estrogen Receptor/ERR, Reductase

Synonym: L-5-Vinyl-2-thiooxazolidone,(S)-Goitrin,(S)-Goitrin ; L-5-Vinyl-2-thiooxazolidone

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02779	Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)	Human	Baculovirus-Insect Cells
	Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoant...
TMPK-00874	Thyroid Peroxidase Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormon...
TMPY-04127	CIp4 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	CIp4 Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells with His tag. The predicted molecular weight is 64 kDa. Accession number: Q15642-2
TMPY-06821	THRB Protein, Human, Recombinant (His)	Human	E. coli
	Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-bin...
TMPY-04853	TSHR Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed pre...
TMPY-03120	Prostaglandin D2 Synthase Protein, Human, Recombinant (His)	Human	HEK293
	PTGDS, also known as L-PGDS, belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic mole...
TMPY-01084	TrkA Protein, Human, Recombinant (His)	Human	HEK293
	TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPY-00908	Renin Protein, Human, Recombinant (His)	Human	HEK293
	Renin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sod...
TMPY-01803	FOLR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i...
TMPY-01756	Transthyretin Protein, Human, Recombinant (His)	Human	HEK293
	Prealbumin/Transthyretin, also known as ATTR, Prealbumin, TTR and PALB, is a secreted and cytoplasm protein that belongs to the Prealbumin / Transthyretin family. Prealbumin / Transthyretin is detected in serum and cereb...
TMPY-01815	FOLR1 Protein, Human, Recombinant (His)	Human	HEK293
	The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i...
TMPY-06022	FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i...
TMPY-02287	Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	X-ray repair cross-complementing protein 5, also known as 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 8 kDa subunit, CTC box-binding factor 85 kDa subunit, DNA repa...
TMPY-01012	P4HB Protein, Human, Recombinant (His)	Human	HEK293
	Protein disulfide-isomerase, also known as Cellular thyroid hormone-binding protein, Prolyl 4-hydroxylase subunit beta, p55 and P4HB, is a peripheral membrane protein that belongs to the protein disulfide isomerase famil...
TMPY-00988	Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,...
TMPY-00873	Lipocalin-2/LCN2 Protein, Human, Recombinant (His)	Human	HEK293
	Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,...
TMPY-02358	CD98 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-01938	CD98 Protein, Human, Recombinant (His)	Human	HEK293
	4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPH-02203	THRA Protein, Human, Recombinant (His)	Human	E. coli
	Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.; Does not bind thyroid hormone and functions as a...
TMPY-03502	PAX8 Protein, Human, Recombinant (His)	Human	E. coli
	PAX8 gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. PAX8 i...
TMPH-02120	SLC5A5 Protein, Human, Recombinant (His)	Human	E. coli
	Mediates iodide uptake in the thyroid gland.
TMPH-02565	Cathepsin K Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thy...
TMPH-02684	GPHB5 Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid ce...
TMPH-02685	GPHB5 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid ce...
TMPH-02947	Transthyretin Protein, Mouse, Recombinant	Mouse	E. coli
	Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
TMPH-02946	Transthyretin Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
TMPH-03262	Cathepsin K Protein, Rat, Recombinant (His)	Rat	E. coli
	Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in...
TMPH-02242	Transthyretin Protein, Human, Recombinant (hFc & Myc)	Human	HEK293
	Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
TMPH-01061	Cathepsin K Protein, Human, Recombinant (His)	Human	E. coli
	Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in...
TMPH-02204	THRB Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
TMPY-01584	PR-Set7 Protein, Human, Recombinant	Human	E. coli
	KMT5A (known as PR-Set7/9, SETD8 and SET8), a member of the SET domain containing methyltransferase family specifically targeting H4K20 for methylation, has been implicated in multiple biological processes. Inhibition of...
TMPY-04465	PKM2 Protein, Human, Recombinant (His)	Human	E. coli
	Pyruvate kinase isozymes M2 also known as pyruvate kinase muscle isozyme 2 (PKM2), pyruvate kinase type K, cytosolic thyroid hormone-binding protein (CTHBP), thyroid hormone-binding protein 1 (THBP1), or opa-interacting ...
TMPY-04766	PKM2 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Pyruvate kinase isozymes M2 also known as pyruvate kinase muscle isozyme 2 (PKM2), pyruvate kinase type K, cytosolic thyroid hormone-binding protein (CTHBP), thyroid hormone-binding protein 1 (THBP1), or opa-interacting ...
TMPH-01059	Cathepsin B Protein, Human, Recombinant (GST)	Human	E. coli
	Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobuli...
TMPY-01256	TBG Protein, Human, Recombinant (His)	Human	HEK293
	Thyroxine-binding globulin, also known as T4-binding globulin, Serpin A7 and TBG, is a secreted protein that belongs to the serpin family. TBG is synthesized primarily in the liver as a 54 kDa protein.TBG is genomically ...
TMPY-01240	TBG Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Thyroxine-binding globulin, also known as T4-binding globulin, Serpin A7 and TBG, is a secreted protein that belongs to the serpin family. TBG is synthesized primarily in the liver as a 54 kDa protein.TBG is genomically ...
TMPJ-01319	TINAGL1 Protein, Human, Recombinant (His)	Human	Human Cells
	TINAGL1 is a secreted protein and contains one SMB (somatomedin-B) domain. TINAGL1 is expressed in aorta, lymph nodes, heart, bone marrow, placenta, lung, kidney, skeletal muscle, pancreas, thyroid, adrenal gland and so ...
TMPY-00483	Parvalbumin/PVALB Protein, Human, Recombinant (His)	Human	E. coli
	Parvalbumins (PVALBs) are particularly abundant in the fast-contracting muscles and correlate positively with muscle relaxation speed in amphibians and fishes. The loss of PVALB plays a role in the pathogenesis of thyroi...
TMPY-04624	Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His)	Mouse	HEK293
	PTGDS, also known as L-PGDS, belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic mole...
TMPY-05069	Prostaglandin D2 Synthase Protein, Rat, Recombinant (His)	Rat	HEK293
	PTGDS, also known as L-PGDS, belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic mole...
TMPH-01251	DUSP26 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis...
TMPY-01617	SULT1B1 Protein, Human, Recombinant (His)	Human	E. coli
	Sulfotransferase family cytosolic 1B member 1, also known as Sulfotransferase 1B1, Sulfotransferase 1B2, Thyroid hormone sulfotransferase, SULT1B1 and ST1B2, is a cytoplasm protein that belongs to the sulfotransferase 1 ...
TMPY-03784	GPHA2 Protein, Human, Recombinant (His)	Human	HEK293
	GPHA2 is a member of the glycoprotein hormones subunit alpha family. Glycoprotein hormones consist of two subunits, the common alpha- and specific beta-subunits, which associate noncovalently to form a heterodimer. The a...
TMPH-01794	NR2F6 Protein, Human, Recombinant (His & Myc)	Human	HEK293
	Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are a...
TMPY-03812	GPHA2 Protein, Human, Recombinant (mFc)	Human	HEK293
	GPHA2 is a member of the glycoprotein hormones subunit alpha family. Glycoprotein hormones consist of two subunits, the common alpha- and specific beta-subunits, which associate noncovalently to form a heterodimer. The a...
TMPJ-00656	SULT1C2 Protein, Human, Recombinant (His)	Human	E. coli
	Sulfotransferase 1C2 (SULT1C2) is a cytosolic enzyme member of the Sulfotransferase 1 family. Human SULT1C2 is primarily expressed in the adult stomach, kidney and thyroid gland, and in the fetal kidney and liver. SULT1C...
TMPJ-00793	TPM3 Protein, Human, Recombinant	Human	E. coli
	Tropomyosin Alpha-3 Chain (TPM3) is a member of the Tropomyosin family. TPM3 exists as a heterodimer consisting of an alpha and a beta chain. TPM3 plays a central role in association with the Troponin complex and in the ...
TMPH-01795	NR2F6 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are a...
TMPJ-00705	BCAS2 Protein, Human, Recombinant (His, T7)	Human	E. coli
	Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell li...
TMPJ-01260	WBP2 Protein, Human, Recombinant (His)	Human	E. coli
	WW Domain-Binding Protein 2 (WBP2) is a ubiquitous protein that contains one GRAM domain. The WW domain is composed of 38 to 40 semi-conserved AA shared by proteins of diverse functions including structural, regulatory, ...
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Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

TMPY-02779

Species: Human

Expression System: Baculovirus-Insect Cells

Thyroid Peroxidase Protein, Mouse, Recombinant (His)

TMPK-00874

Species: Mouse

Expression System: HEK293

CIp4 Protein, Human, Recombinant (His)

TMPY-04127

Species: Human

Expression System: Baculovirus-Insect Cells

THRB Protein, Human, Recombinant (His)

TMPY-06821

Species: Human

Expression System: E. coli

TSHR Protein, Human, Recombinant (His)

TMPY-04853

Species: Human

Expression System: Baculovirus-Insect Cells

Prostaglandin D2 Synthase Protein, Human, Recombinant (His)

TMPY-03120

Species: Human

Expression System: HEK293

TrkA Protein, Human, Recombinant (His)

TMPY-01084

Species: Human

Expression System: HEK293

Renin Protein, Human, Recombinant (His)

TMPY-00908

Species: Human

Expression System: HEK293

FOLR1 Protein, Mouse, Recombinant (His)

TMPY-01803

Species: Mouse

Expression System: HEK293

Transthyretin Protein, Human, Recombinant (His)

TMPY-01756

Species: Human

Expression System: HEK293

FOLR1 Protein, Human, Recombinant (His)

TMPY-01815

Species: Human

Expression System: HEK293

FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-06022

Species: Cynomolgus,Rhesus

Expression System: HEK293

Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His)

TMPY-02287

Species: Human

Expression System: Baculovirus-Insect Cells

P4HB Protein, Human, Recombinant (His)

TMPY-01012

Species: Human

Expression System: HEK293

Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His)

TMPY-00988

Species: Mouse

Expression System: HEK293

Lipocalin-2/LCN2 Protein, Human, Recombinant (His)

TMPY-00873

Species: Human

Expression System: HEK293

CD98 Protein, Mouse, Recombinant (His)

TMPY-02358

Species: Mouse

Expression System: HEK293

CD98 Protein, Human, Recombinant (His)

TMPY-01938

Species: Human

Expression System: HEK293

THRA Protein, Human, Recombinant (His)

TMPH-02203

Species: Human

Expression System: E. coli

PAX8 Protein, Human, Recombinant (His)

TMPY-03502

Species: Human

Expression System: E. coli

SLC5A5 Protein, Human, Recombinant (His)

TMPH-02120

Species: Human

Expression System: E. coli

Cathepsin K Protein, Mouse, Recombinant (His)

TMPH-02565

Species: Mouse

Expression System: E. coli

GPHB5 Protein, Mouse, Recombinant (His)

TMPH-02684

Species: Mouse

Expression System: Yeast

GPHB5 Protein, Mouse, Recombinant (His & Myc)

TMPH-02685

Species: Mouse

Expression System: E. coli

Transthyretin Protein, Mouse, Recombinant

TMPH-02947

Species: Mouse

Expression System: E. coli

Transthyretin Protein, Mouse, Recombinant (His & SUMO)

TMPH-02946

Species: Mouse

Expression System: E. coli

Cathepsin K Protein, Rat, Recombinant (His)

TMPH-03262

Species: Rat

Expression System: E. coli

Transthyretin Protein, Human, Recombinant (hFc & Myc)

TMPH-02242

Species: Human

Expression System: HEK293

Cathepsin K Protein, Human, Recombinant (His)

TMPH-01061

Species: Human

Expression System: E. coli

THRB Protein, Human, Recombinant (His & SUMO)

TMPH-02204

Species: Human

Expression System: E. coli

PR-Set7 Protein, Human, Recombinant

TMPY-01584

Species: Human

Expression System: E. coli

PKM2 Protein, Human, Recombinant (His)

TMPY-04465

Species: Human

Expression System: E. coli

PKM2 Protein, Mouse, Recombinant (His)

TMPY-04766

Species: Mouse

Expression System: Baculovirus-Insect Cells

Cathepsin B Protein, Human, Recombinant (GST)

TMPH-01059

Species: Human

Expression System: E. coli

TBG Protein, Human, Recombinant (His)

TMPY-01256

Species: Human

Expression System: HEK293

TBG Protein, Mouse, Recombinant (His)

TMPY-01240

Species: Mouse

Expression System: HEK293

TINAGL1 Protein, Human, Recombinant (His)

TMPJ-01319

Species: Human

Expression System: Human Cells

Parvalbumin/PVALB Protein, Human, Recombinant (His)

TMPY-00483

Species: Human

Expression System: E. coli

Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His)

TMPY-04624

Species: Mouse

Expression System: HEK293

Prostaglandin D2 Synthase Protein, Rat, Recombinant (His)

TMPY-05069

Species: Rat

Expression System: HEK293

DUSP26 Protein, Human, Recombinant (His & SUMO)

TMPH-01251

Species: Human

Expression System: E. coli

SULT1B1 Protein, Human, Recombinant (His)

TMPY-01617

Species: Human

Expression System: E. coli

GPHA2 Protein, Human, Recombinant (His)

TMPY-03784

Species: Human

Expression System: HEK293

NR2F6 Protein, Human, Recombinant (His & Myc)

TMPH-01794

Species: Human

Expression System: HEK293

GPHA2 Protein, Human, Recombinant (mFc)

TMPY-03812

Species: Human

Expression System: HEK293

SULT1C2 Protein, Human, Recombinant (His)

TMPJ-00656

Species: Human

Expression System: E. coli

TPM3 Protein, Human, Recombinant

TMPJ-00793

Species: Human

Expression System: E. coli

NR2F6 Protein, Human, Recombinant (His & SUMO)

TMPH-01795

Species: Human

Expression System: E. coli

BCAS2 Protein, Human, Recombinant (His, T7)

TMPJ-00705

Species: Human

Expression System: E. coli

WBP2 Protein, Human, Recombinant (His)

TMPJ-01260

Species: Human

Expression System: E. coli

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カタログ番号	製品名
L1510	Nuclear Receptor Compound Library	531 compounds
	A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;
L2400	Endocrinology-Hormone Compound Library	784 compounds
	A unique collection of 784 compounds targeting endocrine system for high throughput screening (HTS) and high content screening (HCS) for new drugs;

ライブラリー

Nuclear Receptor Compound Library

L1510

Compounds: 531

Endocrinology-Hormone Compound Library

L2400

Compounds: 784