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天然化合物

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カタログ番号	製品名	別名	ターゲット
T4262	BisfluoroModafinil		Dopamine Receptor
	CRL-40940 is a selective dopaminergic reuptake inhibitor		Dopamine Receptor
T0940	Acesulfame Potassium		Others
	Acesulfame potassium is a non-nutritive sweetener.		Others
T7829	FK962		Somatostatin
	FK962 is an somatostatin release enhancer , exerts cognitive-enhancing actions.		Somatostatin
T11689	ITI-214	ITI214	PDE
	ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = ...		PDE
T9070	ASP2905	ASP-2905	Potassium Channel
	ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene. It can cross the blood-brain barrier and has antipsychotic activities		Potassium Channel
T0322	Fipexide		Dopamine Receptor , AChR
	Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983. It was served as a nootropic drug in France and Italy, mainly for the therapy of senile dementia, but is...		Dopamine Receptor , AChR
T8737	GR 125743		5-HT Receptor
	GR 125743 is a novel antagonist of 5-HT1B/1D receptor.		5-HT Receptor
T4576	Perospirone	Lullan	Dopamine Receptor , 5-HT Receptor
	Perospirone (Lullan) is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist.		Dopamine Receptor , 5-HT Receptor
T12165	NAChR agonist 1	DUN71755	AChR
	nAChR agonist 1 (DUN71755) is a brain-permeable and orally efficacious positive allosteric α7 nicotinic acetylcholine receptor (α7 nAChR)modulator.		AChR
T8390	Cefazolin		Others , Antibacterial , Antibiotic
	Cefazolin is a semi-synthetic cephalosporin that has a broad spectrum of antibacterial activity and inhibits the synthesis of bacterial cell walls.		Others , Antibacterial , Antibiotic
T22012	7BIO		FLT , DYRK , Aurora Kinase
	7-bromoindirubin-3'-oxime (7BIO) is a caspase independent nonapoptotic cell death inducer. 7BIO is an inhibitor of FLT3, DYRK1A, DYRK2, Aurora B and Aurora C kinases.		FLT , DYRK , Aurora Kinase
T8720	PRX-07034 hydrochloride	PRX-07034	5-HT Receptor
	PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents. PRX-07034 hydrochloride is both a poten...		5-HT Receptor
T7530	PD146176	NSC168807	Ferroptosis , Lipoxygenase , Autophagy
	PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology...		Ferroptosis , Lipoxygenase , Autophagy
T28368	PF-04859989 HCl	PF 04859989,PF04859989,PF-04859989HCl,PF-04859989	Others
	PF-04859989 HCl is a brain-penetrable irreversible inhibitor of kynurenine amino transferase II (KAT II), the enzyme responsible for most of the brain synthesis of kynurenic acid. PF-04859989 HCl has been implicated in s...		Others
T2150	Guanfacine hydrochloride	Tenex,Intuniv,Guanfacine	Adrenergic Receptor
	Guanfacine hydrochloride (Intuniv) is a centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.		Adrenergic Receptor
T22016	A-582941 dihydrochloride	A 582941	5-HT Receptor , AChR
	A-582941 dihydrochloride (A 582941) is a Selective agonist of α7 nAChR partial		5-HT Receptor , AChR
T7823	IDRA-21		GluR
	IDRA-21 is a positive AMPA receptor modulator.		GluR
T23008L	MMPIP hydrochloride	MMPIP hydrochloride (479077-02-6 Free base)	GluR
	MMPIP hydrochloride is a selective antagonist of allosteric mGluR7. MMPIP hydrochloride can be used in research on the roles of mGluR7 on central nervous system functions.		GluR
T1780	Parecoxib	SC 69124,Vorth-P,Valus-P	COX
	Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.		COX
T6493	Escitalopram Oxalate	Cipralex,(S)-(+)Citalopram oxalate	Others , 5-HT Receptor , Serotonin Transporter
	Escitalopram Oxalate ((S)-(+)Citalopram oxalate) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.		Others , 5-HT Receptor , Serotonin Transporter
T7165	Basmisanil	RG1662,RO5186582	GABA Receptor
	Basmisanil (RG1662) is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the treatment of cognitive impairments associated with Down syndro...		GABA Receptor
T8136	Perospirone hydrochloride	Perospirone HCl,SM-9018 hydrochloride	Dopamine Receptor , 5-HT Receptor
	Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist.		Dopamine Receptor , 5-HT Receptor
T0953	Cefazolin sodium	Ancef,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin	Others , Antibacterial , Antibiotic
	Cefazolin sodium (cephazolin sodium) salt binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cefazolin sodium salt is the sodium salt of cefazolin, a beta...		Others , Antibacterial , Antibiotic
T1406	Amantadine hydrochloride	1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride	Dopamine Receptor , Influenza Virus
	Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.		Dopamine Receptor , Influenza Virus
T19706	Ro 20-1724	Ro-20-1724,4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone,Ro20-1724	PDE
	Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.		PDE
T0183	Pramiracetam	CI-879	Others
	Pramiracetam (CI-879), derived from piracetam, is a more effective nootropic drug . According to reports, Pramiracetam improved cognitive defects related with traumatic brain wounds. Pramiracetam was also potent in the t...		Others
T28856	SSR180711 hydrochloride	SSR-180711A HCl,SSR-180711C HCl,SR-180711 HCl	AChR
	SSR180711 hydrochloride (SSR-180711A HCl) is a selective Alpha7 nicotinic acetylcholine partial agonist for the study of neurodegenerative and cognitive disorders.		AChR
T27462	GSK-239512	GSK239512,GSK 239512	Histamine Receptor
	GSK-239512 is an antagonist of H3 receptor and can be used in studies about the treatment of cognitive dysfunction in neurodegenerative disorders.		Histamine Receptor
T13151L	THK5351		Others
	THK5351 is a tracer involved in PET imaging for electron emission tomography imaging of Alzheimer's disease and cognitive impairment.		Others
T1128	Oxiracetam	ISF2522	GABA Receptor
	Oxiracetam (ISF2522), a cyclic derivative of gamma-aminobutyric acid (GABA), is utilized for the treatment of cognitive impairments.		GABA Receptor
T8585	TA-03	7-Methoxytacrine,7-Meota	AChE
	TA-03 (7-Meota) is a potent inhibitor of AChE in treatment of cognitive manifestation of AD.		AChE
T10499	H3 receptor-MO-1		Histamine Receptor
	H3 receptor-MO-1 is a potent modulator of the histamine H3 receptor (H3 receptor) and can be used to study neurodegeneration and cognitive disorders.		Histamine Receptor
T31079	CP-810123	CP 810123,UNII-E6G4550EC4,CP810123	AChR
	CP-810123 is a new alpha 7 nAChR agonist for the treatment of cognitive impairment associated with psychiatric or neurological disorders such as schizophrenia and Alzheimer's disease.		AChR
T30549	BMY-21502	Bms-181168,Bms 181168,Bmy 21502,Bmy21502,Bms181168	Antioxidant
	BMY-21502 is a potential cognitive enhancer that shows anti-hypoxia effects in the KCN-hypoxia model, delays the decay of hippocampal synaptic enhancement in vitro, and can be used to study Alzheimer's disease.		Antioxidant
T27636	Ispronicline	AZD-3480,RJR-1734,AZD 3480,TC 1734,AZD3480,TC-01734,TC-1734-112	AChR
	Ispronicline (TC-1734) An orally active, selective, and potent α4β2 nAChR partial agonist with antidepressant, neuroprotective, and long-lasting cognitive effects.Ispronicline has a high affinity for the α4β2 nAChR with ...		AChR
T7193	Encenicline	EVP-6124	AChR
	Encenicline (EVP-6124) is a selective α7 nicotinic acetylcholine receptor (nAChRs) agonist in development for treating cognitive impairment in schizophrenia and Alzheimer's disease.		AChR
T62839	Dalzanemdor	SAGE-718	NMDAR , iGluR
	Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive dysfunction.		NMDAR , iGluR
T7580	CX546		Autophagy , iGluR
	CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.		Autophagy , iGluR
T0426	Piracetam	UCB-6215	GluR , iGluR
	Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.		GluR , iGluR
T16881	SIB-1553A hydrochloride		AChR
	SIB-1553A hydrochloride is an orally available, selective nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligand.SIB-1553A hydrochloride enhances cognition and may be useful in the study of Alzhei...		AChR
T22378	Nilotinib hydrochloride	AMN-107 HCl	Bcr-Abl , Autophagy
	Nilotinib hydrochloride(AMN-107 HCl) is an orally available Bcr-Abl tyrosine kinase inhibitor with antitumor activity for modulation of neuroinflammation and cognitive deficits, and may be used in studies of chronic myel...		Bcr-Abl , Autophagy
T1884	CX516	Ampakine CX516,BDP 12,Ampalex	GluR , iGluR
	CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI).		GluR , iGluR
T21470L	Davunetide acetate	Davunetide acetate(211439-12-2 Free base)	Beta Amyloid , Microtubule Associated
	Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing peptide and inhibits Aβ aggregation and Aβ-induced neurotoxicit...		Beta Amyloid , Microtubule Associated
T23145	PHA 543613		Others , AChR
	PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.		Others , AChR
T28655	Sabeluzole	R 58735,R58735,R-58735	Microtubule Associated
	Sabeluzole (R-58735) has antiepileptic and cognitive enhancing effects, inhibits neurotoxin-induced tau expression and cell death.Sabeluzole is protective against chlordiazepoxide-induced habituation disorders and may be...		Microtubule Associated
T7108	Omberacetam	SGS-111,Noopept,GVS-111	Others , iGluR
	Omberacetam (Noopept) is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models by a mechanism similar to other related racetam compounds.		Others , iGluR
T14507	Bay 60-7550	BAY 607550	PDE
	Bay 60-7550 is a selective and potent PDE2 inhibitor (Ki: 3.8 nM) that exerts positive inotropic effects on rat heart by increasing PKA-mediated phosphorylation and can be used to ameliorate cognitive impairments and mem...		PDE
T61278	Aminopeptidase-IN-1		Aminopeptidase
	Aminopeptidase-IN-1 is a potent inhibitor of insulin-regulated aminopeptidase (IRAP) (Ki: 7.7 μM).Aminopeptidase-IN-1 can be used in studies of cognitive and memory disorders.		Aminopeptidase
T8451	Tropanserin	MDL 72422	5-HT Receptor
	Tropanserin (MDL 72422) is a 5-hydroxytryptamine receptor antagonist that inhibits 5-HT3 receptor activity.Tropanserin has anxiolytic activity and is used to treat depression and cognitive disorders.		5-HT Receptor
T0869	Atomoxetine hydrochloride	Tomoxetine hydrochloride,(R)-Tomoxetine hydrochloride,LY 139603,Atomoxetine HCl,LY 139603 HCl	Dopamine Receptor , 5-HT Receptor , Norepinephrine
	Atomoxetine hydrochloride (LY 139603) is the hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Althou...		Dopamine Receptor , 5-HT Receptor , Norepinephrine

Compounds

BisfluoroModafinil

T4262

Synonym:

Target: Dopamine Receptor

Target: Potassium Channel

Fipexide

T0322

Synonym:

Target: Dopamine Receptor, AChR

GR 125743

T8737

Synonym:

Target: 5-HT Receptor

Perospirone

T4576

Synonym: Lullan

Target: Dopamine Receptor, 5-HT Receptor

Target: Others, Antibacterial, Antibiotic

7BIO

T22012

Synonym:

Target: FLT, DYRK, Aurora Kinase

PRX-07034 hydrochloride

T8720

Synonym: PRX-07034

Target: 5-HT Receptor

PD146176

T7530

Synonym: NSC168807

Target: Ferroptosis, Lipoxygenase, Autophagy

PF-04859989 HCl

T28368

Synonym: PF 04859989,PF04859989,PF-04859989HCl,PF-04859989

Target: Others

Guanfacine hydrochloride

T2150

Synonym: Tenex,Intuniv,Guanfacine

Target: Adrenergic Receptor

A-582941 dihydrochloride

T22016

Synonym: A 582941

Target: 5-HT Receptor, AChR

Synonym: MMPIP hydrochloride (479077-02-6 Free base)

Target: GluR

Parecoxib

T1780

Synonym: SC 69124,Vorth-P,Valus-P

Target: COX

Escitalopram Oxalate

T6493

Synonym: Cipralex,(S)-(+)Citalopram oxalate

Target: Others, 5-HT Receptor, Serotonin Transporter

Basmisanil

T7165

Synonym: RG1662,RO5186582

Target: GABA Receptor

Perospirone hydrochloride

T8136

Synonym: Perospirone HCl,SM-9018 hydrochloride

Target: Dopamine Receptor, 5-HT Receptor

Cefazolin sodium

T0953

Synonym: Ancef,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin

Target: Others, Antibacterial, Antibiotic

Amantadine hydrochloride

T1406

Synonym: 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride

Target: Dopamine Receptor, Influenza Virus

Ro 20-1724

T19706

Synonym: Ro-20-1724,4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone,Ro20-1724

SSR180711 hydrochloride

T28856

Synonym: SSR-180711A HCl,SSR-180711C HCl,SR-180711 HCl

Target: AChR

GSK-239512

T27462

Synonym: GSK239512,GSK 239512

Target: Histamine Receptor

Target: GABA Receptor

TA-03

T8585

Synonym: 7-Methoxytacrine,7-Meota

Target: Histamine Receptor

CP-810123

T31079

Synonym: CP 810123,UNII-E6G4550EC4,CP810123

Target: AChR

BMY-21502

T30549

Synonym: Bms-181168,Bms 181168,Bmy 21502,Bmy21502,Bms181168

Target: Antioxidant

Ispronicline

T27636

Synonym: AZD-3480,RJR-1734,AZD 3480,TC 1734,AZD3480,TC-01734,TC-1734-112

Target: Autophagy, iGluR

SIB-1553A hydrochloride

T16881

Synonym:

Target: AChR

Nilotinib hydrochloride

T22378

Synonym: AMN-107 HCl

Target: Bcr-Abl, Autophagy

CX516

T1884

Synonym: Ampakine CX516,BDP 12,Ampalex

Target: GluR, iGluR

Davunetide acetate

T21470L

Synonym: Davunetide acetate(211439-12-2 Free base)

Target: Beta Amyloid, Microtubule Associated

Synonym: R 58735,R58735,R-58735

Target: Microtubule Associated

Omberacetam

T7108

Synonym: SGS-111,Noopept,GVS-111

Target: Others, iGluR

Target: Aminopeptidase

Tropanserin

T8451

Synonym: MDL 72422

Target: 5-HT Receptor

Atomoxetine hydrochloride

T0869

Synonym: Tomoxetine hydrochloride,(R)-Tomoxetine hydrochloride,LY 139603,Atomoxetine HCl,LY 139603 HCl

Target: Dopamine Receptor, 5-HT Receptor, Norepinephrine

カタログ番号	製品名	別名	ターゲット
T2S1720	Huperzine B		AChE
	1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's disease therapy.		AChE
T3S0195	Nootkatone		AMPK
	1. Nootkatone can provide effective tick control. 2. (+)-Nootkatone has antiallergic, anti-inflammatory, and antiplatelet activities. 3. Nootkatone can prevent obesity and improve physical performance through AMPK activa...		AMPK
T4954	SMILAGENIN ACETATE	Nsc15488	Others
	Smilagenin acetate is a sapogenin derivative that has been shown to upregulate the expression of the acetylcholine M2 receptor in cell assays, making it a candidate for dementia research.		Others
TN2100	Pratensein		Others , NF-κB
	Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.		Others , NF-κB
T1589	D-Cycloserine	RO-1-9213	Others , Antibacterial , Antibiotic , iGluR
	D-Cycloserine (RO-1-9213) is a broad spectrum antibiotic used as a second line agent for treatment of drug resistant tuberculosis, always in combination with other antituberculosis agents.		Others , Antibacterial , Antibiotic , iGluR
T0185	Escitalopram	Seroplex,S-(+)-Citalopram,(S)-Citalopram	Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor
	Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patien...
T3026	(-)-Huperzine A	HupA,Huperzine A	Apoptosis , AChR , AChE , iGluR
	(-)-Huperzine A (HupA) , an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the tr...		Apoptosis , AChR , AChE , iGluR
T6975	Sarcosine	Sarcosinic acid,Methylaminoacetic acid,Sarcosin,Methylglycine,N-Methylaminoacetic acid,N-methylglycine	Others , GlyT , Endogenous Metabolite
	Sarcosine (Methylglycine) is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist.		Others , GlyT , Endogenous Metabolite
T7060	Amantadine	1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine	Others
	Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake.		Others
T5S0833	Astragaloside III		Antioxidant
	Astragaloside III has cardioprotective effects as well as causing improvement in cognitive function. It can be used in the prevention of cardio-cerebral vascular diseases. It also is antioxidant.		Antioxidant
T4S1519	Pseudoginsenoside RT5		Others
	1. Pseudoginsenoside RT5 has anti-epilepsy, anti-depressant activity by promoting nerve growth and improve cognitive ability. 2. Pseudoginsenoside RT5 has anti-bacterial, anti-tumor and anti-malaria activities.		Others
T3911	Pulchinenoside A	Anemoside A3	Others
	Pulchinenoside A (Anemoside A3) is an attractive candidate for further development as a cognitive enhancer capable of alleviating memory dysfunctions associated with aging and neurodegenerative diseases.		Others
TN2703	2,3-Dihydroxy-4-methoxyacetophenone	2',3'-Dihydroxy-4'-methoxyacetophenone	Calcium Channel
	2,3-Dihydroxy-4-methoxyacetophenone (2',3'-Dihydroxy-4'-methoxyacetophenone) is a natural product,it improves cognitive function and may be helpful for the treatment of Alzheimer's disease.		Calcium Channel
T3902	Atractylenolide III	ICodonolactone,8β-Hydroxyasterolide	Apoptosis
	Atractylenolide III (ICodonolactone) may have therapeutic potential in treating homocysteine-mediated cognitive impairment and neuronal injury. Atractylenolide III is a potential candidate for the treatment of human lung...		Apoptosis
T5702	Tenuifoliside B		Dehydrogenase
	Tenuifoliside B is a natural product from the roots of Polygala tenuifolia.And is a target lactate dehydrogenase inhibitor. Tenuifoliside B has cognitive improving and cerebral protective effects. it can inhibit potassi...		Dehydrogenase
TN1420	Bacopaside I		Others
	Bacopaside I is a saponin isolated from Bacopa monniera. Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer's disease, it ameliorates cognitive impairment in APP/PS1 ...		Others
TN1601	Effusol		Caspase
	Effusol is a natural product, exhibits potent scavenging activity for DPPH and ABTS radicals(IC50 values of 79 μM and 2.73 μM, respectively). Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampa...		Caspase
T32614	L-Clausenamide	(-)-Clausenamide	Microtubule Associated
	L-Clausenamide is an alkaloid extracted from the leaves of the yellow bark (Clausena lansium (Lour) skeels) and can be used to improve cognitive function. L-Clausenamide inhibits beta-amyloid (Aβ) toxicity and prevents t...		Microtubule Associated
T4439	Sn-Glycero-3-phosphocholine	Choline Alfoscerate,Glycerophosphocholine,Glycerophosphorylcholine,Alpha-GPC,Choline glycerophosphate,L-α-GPC	Endogenous Metabolite , AChE
	sn-Glycero-3-phosphocholine (Choline glycerophosphate) is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have a potential for the treatment o...		Endogenous Metabolite , AChE
T3767	Polygalacic acid	Virgaureagenin G	MMP , AChR , AChE
	Polygalacic acid (Virgaureagenin G)(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acetyltransferase (ChAT) activity, and eleva...		MMP , AChR , AChE
T41095	(E)-3-(4-Methoxyphenyl)acrylic acid		Glucosidase
	(E)-3-(4-Methoxyphenyl)acrylic acid is a small molecule compound isolated from the rhizome of Etlingera pavieana (Pierre ex Gagnep.) R. M. Sm. It is a novel α-glucosidase inhibitor. (E)-3-(4-Methoxyphenyl)acrylic acid ha...		Glucosidase
T6S0721	Orientin	Lutexin,Luteolin-8-glucoside	Others
	1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier int...		Others
T3011	2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid	Kynurenine,Dl-Kynurenine,Kynurenin,3-Anthraniloylalanine	Others , Endogenous Metabolite
	2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid (3-Anthraniloylalanine) is a ketone and an amino acid derivative with diverse biological functions, including vasodilatory, immunoregulatory and neuromodulatory activities. 2-...		Others , Endogenous Metabolite
T2563	Acetyl-L-carnitine hydrochloride	Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride	Others , Endogenous Metabolite
	Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neur...		Others , Endogenous Metabolite
T4S0969	Obtusifolin		Antioxidant , NF-κB
	1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be...		Antioxidant , NF-κB
T0591L	Galactose	alpha-D-Galactose
	Galactose prevents cognitive deficits in male Wistar rats.
TN1798	Isorosmanol		Beta Amyloid , AChR
	Isorosmanol possesses antioxidant, neuroprotective and neurotrophic effects, it might be useful in ageing disorders such as the declining of cognitive functions and hyperpigmentation.		Beta Amyloid , AChR
T80631	Esculin sesquihydrate		p38 MAPK
	Esculin sesquihydrate, a coumarin glucoside with fluorescent properties and a constituent of ash bark, improves cognitive deficits associated with experimental diabetic nephropathy (DN). It also offers anti-oxidative and...		p38 MAPK
T81072	Suffruticosol A
	Suffruticosol A, a neuroprotective compound isolated from the seeds of P. lactiflora [1], mitigates scopolamine-induced neurodegenerative cellular damage and improves hippocampal cholinergic function. Additionally, it pa...
T79963	Feralolide
	Feralolide, a dihydroisocoumarin from the methanolic extract of aloe vera resin, functions as a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with IC50 values of 55 μg/mL and 52 μg/mL, ...

天然物製品

Target: Others, NF-κB

D-Cycloserine

T1589

Synonym: RO-1-9213

Target: Others, Antibacterial, Antibiotic, iGluR

Escitalopram

T0185

Synonym: Seroplex,S-(+)-Citalopram,(S)-Citalopram

Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor

(-)-Huperzine A

T3026

Synonym: HupA,Huperzine A

Target: Apoptosis, AChR, AChE, iGluR

Sarcosine

T6975

Synonym: Sarcosinic acid,Methylaminoacetic acid,Sarcosin,Methylglycine,N-Methylaminoacetic acid,N-methylglycine

Target: Others, GlyT, Endogenous Metabolite

Amantadine

T7060

Synonym: 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine

Pseudoginsenoside RT5

Synonym: Anemoside A3

Target: Others

2,3-Dihydroxy-4-methoxyacetophenone

TN2703

Synonym: 2',3'-Dihydroxy-4'-methoxyacetophenone

Target: Calcium Channel

Atractylenolide III

T3902

Synonym: ICodonolactone,8β-Hydroxyasterolide

Target: Dehydrogenase

Synonym: (-)-Clausenamide

Target: Microtubule Associated

sn-Glycero-3-phosphocholine

T4439

Synonym: Choline Alfoscerate,Glycerophosphocholine,Glycerophosphorylcholine,Alpha-GPC,Choline glycerophosphate,L-α-GPC

Target: Endogenous Metabolite, AChE

Polygalacic acid

T3767

Synonym: Virgaureagenin G

Target: MMP, AChR, AChE

(E)-3-(4-Methoxyphenyl)acrylic acid

Synonym: Lutexin,Luteolin-8-glucoside

Target: Others

2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

T3011

Synonym: Kynurenine,Dl-Kynurenine,Kynurenin,3-Anthraniloylalanine

Target: Others, Endogenous Metabolite

Acetyl-L-carnitine hydrochloride

T2563

Synonym: Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride

Target: Others, Endogenous Metabolite

Obtusifolin

T4S0969

Synonym:

Target: Antioxidant, NF-κB

Galactose

T0591L

Synonym: alpha-D-Galactose

Target: Beta Amyloid, AChR

Esculin sesquihydrate

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00381	PSMA Protein, Human, Recombinant (His)	Human	HEK293
	Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...
TMPK-00191	PILRA Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance; Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does ...
TMPJ-01114	GAMT Protein, Human, Recombinant (His)	Human	E. coli
	GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily. It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver. GAMT converts guanidoa...
TMPY-04318	GRIK2 Protein, Human, Recombinant (hFc)	Human	HEK293
	GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar...
TMPY-02547	IL-1RAPL1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is a member of the interleukin-1 receptor family. The protein structurally comprises three extracellular immunoglobulin domains, which presumably mediate binding...
TMPY-02374	LSAMP Protein, Human, Recombinant (hFc)	Human	HEK293
	The limbic system-associated membrane protein (LAMP) is a cell surface glycoprotein expressed by cortical and subcortical regions of the mammalian CNS that comprise or receive direct projections from limbic system struct...
TMPY-01036	IL-1RAPL1 Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is a member of the interleukin-1 receptor family. The protein structurally comprises three extracellular immunoglobulin domains, which presumably mediate binding...
TMPY-04033	FGF-14 Protein, Canine, Recombinant	Canine	E. coli
	FGF14 is a member of the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic deve...
TMPY-02804	FGF-14 Protein, Human, Recombinant (isoform 1B)	Human	E. coli
	FGF14 is a member of the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic deve...
TMPY-02383	LSAMP Protein, Human, Recombinant (His)	Human	HEK293
	The limbic system-associated membrane protein (LAMP) is a cell surface glycoprotein expressed by cortical and subcortical regions of the mammalian CNS that comprise or receive direct projections from limbic system struct...
TMPY-00985	IL-1RAPL1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is a member of the interleukin-1 receptor family. The protein structurally comprises three extracellular immunoglobulin domains, which presumably mediate binding...
TMPY-01390	PSMA Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...
TMPY-05269	PSMA Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...
TMPY-06960	PSMA Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...

PSMA Protein, Human, Recombinant (His)

TMPY-00381

Species: Human

Expression System: HEK293

PILRA Protein, Mouse, Recombinant (hFc)

TMPK-00191

Species: Mouse

Expression System: HEK293

GAMT Protein, Human, Recombinant (His)

TMPJ-01114

Species: Human

Expression System: E. coli

GRIK2 Protein, Human, Recombinant (hFc)

TMPY-04318

Species: Human

Expression System: HEK293

IL-1RAPL1 Protein, Mouse, Recombinant (hFc)

TMPY-02547

Species: Mouse

Expression System: HEK293

LSAMP Protein, Human, Recombinant (hFc)

TMPY-02374

Species: Human

Expression System: HEK293

IL-1RAPL1 Protein, Human, Recombinant (His)

TMPY-01036

Species: Human

Expression System: HEK293

FGF-14 Protein, Canine, Recombinant

TMPY-04033

Species: Canine

Expression System: E. coli

FGF-14 Protein, Human, Recombinant (isoform 1B)

TMPY-02804

Species: Human

Expression System: E. coli

LSAMP Protein, Human, Recombinant (His)

TMPY-02383

Species: Human

Expression System: HEK293

IL-1RAPL1 Protein, Human, Recombinant (hFc)

TMPY-00985

Species: Human

Expression System: HEK293

PSMA Protein, Mouse, Recombinant (His)

TMPY-01390

Species: Mouse

Expression System: HEK293

PSMA Protein, Human, Recombinant (His), Biotinylated

TMPY-05269

Species: Human

Expression System: HEK293

PSMA Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06960

Species: Human

Expression System: HEK293

カタログ番号	製品名
L9840	Anti-Alzheimer's Disease Compound Library	986 compounds
	A unique collection of 986 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.
L3300	Histamine & Melatonin Receptor-Targeted Compound Library	153 compounds
	A unique collection of 153 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs;
L2630	Neuronal Differentiation Compound Library	672 compounds

ライブラリー

Anti-Alzheimer's Disease Compound Library

L9840

Compounds: 986

Histamine & Melatonin Receptor-Targeted Compound Library

L3300

Compounds: 153

Neuronal Differentiation Compound Library

L2630

Compounds: 672