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Search Results for " iron "

ターゲット

161

阻害剤

20

天然化合物

96

リコンビナントタンパク質

3

ライブラリー

カタログ番号 製品名 別名 ターゲット
T8132 Iron sucrose Iron saccharate,Sucroferric oxyhydroxide Reactive Oxygen Species
Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.
T0001 Iron(II) fumarate Ferrous fumarate,Iron Fumarate Others
Iron(II) fumarate (Iron Fumarate) is the iron(II) salt of fumaric acid, a reddish-orange powder, applied to supply iron intake.
T9624 iron chloride hexahydrate
iron chloride hexahydrate promoted selective hydroxylation and chlorination of benzyl ketone derivatives for the construction of hetero-quaternary scaffolds.
T35378 Iron (III) hexacyanoferrate (II) Prussian Blue,Berlin blue,Iron (III) hexacyanoferrate (II) Others
Iron (III) hexacyanoferrate (II) is a useful organic compound for research related to life sciences. The catalog number is T35378 and the CAS number is 14038-43-8.
T4505 Ferrous Bisglycinate Bisglycine iron(II) salt,Iron(II) bisglycinate Estrogen/progestogen Receptor
Ferrous Bisglycinate (Bisglycine iron(II) salt) is used in the fortification of infant formulations and foods.
T32193 Iron sorbitex Jectofer,Yectofer,Iron Sorbitol,HSDB 1967,Astra 1572
Iron Sorbitex is used for the treatment of Iron Sorbitex deficiency anemia in patients with chronic kidney disease. Iron Sorbitex can be used as an Iron Sorbitex replacement product used for the treatment of Iron Sorbite...
T35995 Ferrichrome (iron-free)
Ferrichrome (iron-free) is a hydroxamate siderophore produced by various fungi (including U. sphaerogena) that facilitates iron chelation and uptake by these organisms and is also used by bacteria as a heterologous sider...
T35360 Iron Dextran INFeD,Conferon,Fe dextran,Fero Gradumet Others
Iron Dextran is a useful organic compound for research related to life sciences. The catalog number is T35360 and the CAS number is 9004-66-4.
T13692 Ferric maltol Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate Others
Ferric maltol (Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate) is a ferric, non-salt-based oral iron formulation demonstrating improved tolerance in patients with previous intolerance to other iron formulations.
T37851 Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)
Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) is an inducer of ferroptosis.1 It induces ferroptosis, but not apoptosis or necroptosis, in NB1 cancer cells when used at a concentration of 3 μM.1 Chlorido[N,N...
T31786 Ferumoxytol Magnetic Black,Black Iron BM,Magnetic oxide,Black Gold F 89,11557 Black Others
Ferumoxytol (Magnetic Black) is a non-gadolinium based contrast agent for use in magnetic resonance imaging applications.
T66117 Iron(II) sulfate heptahydrate
Iron(II) sulfate heptahydrate is a useful organic compound for research related to life sciences and the catalog number is T66117.
T11064 DMT1 blocker 2 Others
DMT1 blocker 2, compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 hydrogen peroxide value of 0.83, which is expected to block iron uptake by intestinal epithelial cells in vivo.
T8533 ML318 Others , Antibiotic
ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of...
T8500 VLX600 OXPHOS , Mitochondrial Metabolism , Autophagy
VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent. It acts by reducing mitochondrial oxidative phosphorylation in tumor cells.
T9627 PHD-1-IN-1 HIF/HIF Prolyl-Hydroxylase
PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM).
T50099 HIF-2α-IN-4 Others , HIF/HIF Prolyl-Hydroxylase
HIF-2a translation inhibitor is a compound used as a molecular building block.
T1457 Deferasirox ICL 670,CGP-72670 Others , Ferroptosis , Antibacterial
Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload.
T19692 Deferitrin GT 56252,GT 56 252,GT-56252,GT-56-252 Others
Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.
T13396 Zinc Protoporphyrin Zinc Protoporphyrin-9,ZnPP,Zn(II)-protoporphyrin IX Apoptosis , Reactive Oxygen Species , Endogenous Metabolite
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive inhibitor of heme oxygenase-1 (HO-1) and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2, and has anti-can...
T64977 Naphthol green B
Naphthol green B is a useful organic compound for research related to life sciences. The catalog number is T64977 and the CAS number is 19381-50-1.
T71138L Binospirone MDL 73005EF 5-HT Receptor
Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of glaucoma and movement disorders associated with neurologic dysfunction.
T68172 Zalospirone 5-HT Receptor
Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.
T2132 Buspirone hydrochloride Buspirone HCl,Narol,Buspar Dopamine Receptor , 5-HT Receptor
Buspirone hydrochloride (Buspar) is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD).
T22871 Ipsapirone 5-HT Receptor
Ipsapirone is a partial agonist of 5-HT1A receptor and produces an inhibitory effect on 5-HT2 and the α1-adrenergic function at high doses.
T8136 Perospirone hydrochloride Perospirone HCl,SM-9018 hydrochloride Dopamine Receptor , 5-HT Receptor
Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist.
T21011 Buspirone Buspirone free base,Ansial 5-HT Receptor
Buspirone (Buspirone free base) is an azaspiro compound which has a role as an anxiolytic drug, a sedative, a serotonergic agonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor.
T3179 Eptapirone F 11440 5-HT Receptor
Eptapirone (F 11440) is a highly effective and selective 5-HT1A receptor agonist with marked antidepressant and anxiolytic potential.
T7412 Tandospirone citrate SM-3997 citrate 5-HT Receptor
Tandospirone citrate (SM-3997 citrate) is a potent and selective 5-HT1A receptor partial agonist (Ki : 27 nM)
T67961 Safironil Others
safironil is a novel antifibrotic compound and a competitive inhibitor of collagen synthesis. safironil inhibited in vitro experiments on fibroblast activation monitored by collagen I mRNA or smooth muscle alpha-actin le...
T0476 Spironolactone SC9420,Abbolactone Glucocorticoid Receptor , Androgen Receptor , Autophagy
Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.
T24885L Tiaspirone hydrochloride BMY-13859 hydrochloride,Tiaspirone hydrochloride(87691-91-6 Free base) Dopamine Receptor , 5-HT Receptor
Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity. Tiaspirone hydrochloride influences the electrophysiological activity of dopaminergic neurons in the substantia nigra zona compacta (A9 ...
T24885 Tiospirone BMY 13859-1 Dopamine Receptor , 5-HT Receptor
Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and dopamine blocker that inhibits D2, 5-HT1a, 5-HT7, and sigma receptors.Tiospirone is used in the study of neurological disorders such as schizophrenia.
T4576 Perospirone Lullan Dopamine Receptor , 5-HT Receptor
Perospirone (Lullan) is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist.
T28827 Sofpironium bromide BBI4000,BBI 4000,BBI-4000 Others , AChR
Sofpironium bromide (BBI4000) belongs to a class of drugs called anticholinergics, which exert their effect by blocking the action of acetylcholine.
T19917 Gepirone 5-HT Receptor
Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.
T24923 Umespirone Umespirona,Umespironum
Umespirone is a potential antipsychotic/anxiolytic drug of the azapirone class. It possesses anxiolytic and antipsychotic properties.
T30179 Astiron Astyron
Astiron is a self-expanding bare-metal nitinol stent.
T29480 7alpha-Thiospironolactone Deacetylspironolactone
7α-Thio Spironolactone is a Spironolactone (sc-204294) metabolite.
T26709 Azadirone
Azadirone is a limonoid tetranortriterpene. Azadirone can sensitize cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through ROS-ERK-CHOP-mediated up-regulation of DR4 and DR5 signaling, do...
T69038 Teroxirone
Teroxirone, also known as Triglycidyl Isocyanurate and Tris(2,3-epoxypropyl) Isocyanurate, is a triazene triepoxide with antineoplastic activity. Teroxine alkylates and cross-links DNA, thereby inhibiting DNA replicatio...
T70666 Alnespirone hydrochloride
Alnespirone hydrochloride is a selective 5-HT1A receptor full agonist of the azapirone chemical class. It has both antidepressant and anxiolytic effects.
T16543 Pironetin Microtubule Associated
Pironetin binds to α-tubulin and is an effective inhibitor of microtubule polymerization. It also has cell cycle arrest and antitumor activity. Pironetin is an α/β unsaturated lactone isolated from Streptomyces species.
T70814 Alnespirone
Alnespirone, also known as S-20499, is a selective 5-HT1A receptor full agonist of the azapirone chemical class. It has both antidepressant and anxiolytic effects.
T69034 Enilospirone
Enilospirone is a selective 5-HT1A receptor agonist of the azapirone class.
T9163 IRONE Others
Irone is used as a fragrance ingredient.
T68715 Anaxirone
Anaxirone is a synthetic triepoxide alkylating agent with potential antineoplastic activity. Anaxirone alkylates DNA via actual or derived epoxide groups, resulting in inhibition of DNA synthesis. This agent has been sho...
TQ0315 Tandospirone SM-3997 5-HT Receptor
Tandospirone (SM-3997) is a selective partial agonist of 5-HT1A receptor (Ki: 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Kis: 1300-41000 nM).
T34887 Tiron free acid
Tiron free acid is a bioactive chemical.
T125947 Amorphispironone
Amorphispironone is a useful organic compound for research related to life sciences. The catalog number is T125947 and the CAS number is 139006-28-3.

Compounds

Iron sucrose
T8132
Synonym: Iron saccharate,Sucroferric oxyhydroxide
Target: Reactive Oxygen Species
Iron(II) fumarate
T0001
Synonym: Ferrous fumarate,Iron Fumarate
Target: Others
iron chloride hexahydrate
T9624
Synonym:
Target:
Iron (III) hexacyanoferrate (II)
T35378
Synonym: Prussian Blue,Berlin blue,Iron (III) hexacyanoferrate (II)
Target: Others
Ferrous Bisglycinate
T4505
Synonym: Bisglycine iron(II) salt,Iron(II) bisglycinate
Target: Estrogen/progestogen Receptor
Iron sorbitex
T32193
Synonym: Jectofer,Yectofer,Iron Sorbitol,HSDB 1967,Astra 1572
Target:
Ferrichrome (iron-free)
T35995
Synonym:
Target:
Iron Dextran
T35360
Synonym: INFeD,Conferon,Fe dextran,Fero Gradumet
Target: Others
Ferric maltol
T13692
Synonym: Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate
Target: Others
Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)
T37851
Synonym:
Target:
Ferumoxytol
T31786
Synonym: Magnetic Black,Black Iron BM,Magnetic oxide,Black Gold F 89,11557 Black
Target: Others
Iron(II) sulfate heptahydrate
T66117
Synonym:
Target:
DMT1 blocker 2
T11064
Synonym:
Target: Others
ML318
T8533
Synonym:
Target: Others, Antibiotic
VLX600
T8500
Synonym:
Target: OXPHOS, Mitochondrial Metabolism, Autophagy
PHD-1-IN-1
T9627
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase
HIF-2α-IN-4
T50099
Synonym:
Target: Others, HIF/HIF Prolyl-Hydroxylase
Deferasirox
T1457
Synonym: ICL 670,CGP-72670
Target: Others, Ferroptosis, Antibacterial
Deferitrin
T19692
Synonym: GT 56252,GT 56 252,GT-56252,GT-56-252
Target: Others
Zinc Protoporphyrin
T13396
Synonym: Zinc Protoporphyrin-9,ZnPP,Zn(II)-protoporphyrin IX
Target: Apoptosis, Reactive Oxygen Species, Endogenous Metabolite
Naphthol green B
T64977
Synonym:
Target:
Binospirone
T71138L
Synonym: MDL 73005EF
Target: 5-HT Receptor
Zalospirone
T68172
Synonym:
Target: 5-HT Receptor
Buspirone hydrochloride
T2132
Synonym: Buspirone HCl,Narol,Buspar
Target: Dopamine Receptor, 5-HT Receptor
Ipsapirone
T22871
Synonym:
Target: 5-HT Receptor
Perospirone hydrochloride
T8136
Synonym: Perospirone HCl,SM-9018 hydrochloride
Target: Dopamine Receptor, 5-HT Receptor
Buspirone
T21011
Synonym: Buspirone free base,Ansial
Target: 5-HT Receptor
Eptapirone
T3179
Synonym: F 11440
Target: 5-HT Receptor
Tandospirone citrate
T7412
Synonym: SM-3997 citrate
Target: 5-HT Receptor
Safironil
T67961
Synonym:
Target: Others
Spironolactone
T0476
Synonym: SC9420,Abbolactone
Target: Glucocorticoid Receptor, Androgen Receptor, Autophagy
Tiaspirone hydrochloride
T24885L
Synonym: BMY-13859 hydrochloride,Tiaspirone hydrochloride(87691-91-6 Free base)
Target: Dopamine Receptor, 5-HT Receptor
Tiospirone
T24885
Synonym: BMY 13859-1
Target: Dopamine Receptor, 5-HT Receptor
Perospirone
T4576
Synonym: Lullan
Target: Dopamine Receptor, 5-HT Receptor
Sofpironium bromide
T28827
Synonym: BBI4000,BBI 4000,BBI-4000
Target: Others, AChR
Gepirone
T19917
Synonym:
Target: 5-HT Receptor
Umespirone
T24923
Synonym: Umespirona,Umespironum
Target:
Astiron
T30179
Synonym: Astyron
Target:
7alpha-Thiospironolactone
T29480
Synonym: Deacetylspironolactone
Target:
Azadirone
T26709
Synonym:
Target:
Teroxirone
T69038
Synonym:
Target:
Alnespirone hydrochloride
T70666
Synonym:
Target:
Pironetin
T16543
Synonym:
Target: Microtubule Associated
Alnespirone
T70814
Synonym:
Target:
Enilospirone
T69034
Synonym:
Target:
IRONE
T9163
Synonym:
Target: Others
Anaxirone
T68715
Synonym:
Target:
Tandospirone
TQ0315
Synonym: SM-3997
Target: 5-HT Receptor
Tiron free acid
T34887
Synonym:
Target:
Amorphispironone
T125947
Synonym:
Target:
1 2 3 4
カタログ番号 製品名 別名 ターゲット
T20819 Ammonium iron(III) citrate Ferric ammonium citrate Others , Ferroptosis
Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload leading to cellular iron death and enhances protein production.
T6569 Mimosine Leucenine,NSC 69188,Leucenol,L-Mimosine Others
L-Mimosine (Leucenol) is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.
TN1023 Miltirone P450 , GABA Receptor
Miltirone is a CYPs inhibitor, it has been characterized as a low-affinity ligand for central benzodiazepine receptors.
TN4441 Linderaspirone A Others
Linderaspirone A shows significant activity against glucosamine-inducedinsulin resistance.
T83425 1-Oxomiltirone
2-Isopropyl-8,8-dimethyl-7,8-dihydrophenanthrene-3,4,5(6H)-trione, a C20-norabietane diterpenoid exhibiting anti-inflammatory properties, is isolated from sage leaves [1].
TN1562 Dehydromiltirone NOS , NF-κB , COX
Dehydromiltirone has antioxidant activity, it shows significant anti-neuroinflammatory effects through inhibiting PI3K/Akt phosphorylation and then inhibiting NF-κB signaling pathway.
T73797 Cladospirone bisepoxide
Cladospirone bisepoxide, a metabolite isolated from fungal cultures, exhibits selective antibiotic activity against various bacteria and fungi, and at low concentrations, it inhibits the germination of Lepidium sativum [...
T38373 2-heptyl-3-hydroxy-4(1H)-Quinolone 2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal Others
2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) is a quorum-sensing signalling molecule produced by Pseudomonas aeruginosa in response to increased cell density. It increases the expression of the lasB ...
T7210 Guanosine 5'-diphosphate GDP Endogenous Metabolite
Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.
T5515 Hemin Hemin chloride Mitophagy , Ferroptosis , Autophagy
Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer. Hemin has therapeutic activity in porphyrias by reducing heme deficiency in patients, thereby inhibiting δ-aminolevulini...
T4S2126 Ginkgetin Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...
TN4220 Homobutein 3-O-Methylbutein,2',4,4'-Trihydroxy-3-methoxychalcone Antioxidant , NF-κB , HDAC , Parasite , Immunology/Inflammation related
T8948 Ferroheme protoheme,Hematin,heme Others
Ferroheme (protoheme) is the color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins. A Ferroheme or haem is a prosthetic group that consists of an iron atom c...
T2S0843 Negletein 7-O-Methylbaicalein,Baicalein-7-methylether IL Receptor , TNF , NOS , Interleukin
1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n...
T1040 Vitamin B12 Cyanocobalamin,Cobalamin Endogenous Metabolite
Cyanocobalamin is a cobalt-containing coordination compound generated by intestinal microbes and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intes...
T3415 Secoisolariciresinol diglucoside LGM2605 ROS
Secoisolariciresinol diglucoside (LGM2605) was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol diglucoside (25 mg/kg b.w.) exerts the antihyperglycemic effect ...
TJS0315 4-Methyldaphnetin 7,8-Dihydroxy-4-methylcoumarin,DHMC Apoptosis , Lipoxygenase
4-Methyldaphnetin (DHMC) is a potent inhibitor (low micromolar) of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals, but may be pro-oxidant (enhancing generation of hydr...
T5075 Phytic acid potassium Inositol hexakisphosphate dipotassium salt,Phytic acid dipotassium salt,Fytic Acid dipotassium salt,Inositol polyphosphate dipotassium salt Others , Endogenous Metabolite
Phytic acid potassium (Inositol polyphosphate dipotassium salt) exists in all eukaryotic cells. In plants, it is known to function as a [PO4]3 storage depot and precursor for other inositol phosphates and pyrophosphates....
T72594 Broussochalcone A
Broussochalcone A, an antioxidant and Xanthine Oxidase inhibitor (IC 50 =2.21 μM), exhibits free radical scavenging activity. It prevents iron-induced lipid peroxidation and nitric oxide synthesis in lipopolysaccharide (...
TN3364 Agrimonolide Apoptosis , Dehydrogenase , p38 MAPK , ROS , JAK
Agrimonolide, a compound derived from isocoumarins and found mainly in the herb Agrimonia pilosa Ledeb, has significant biological activity. agrimonolide exerts anti-inflammatory effects by inhibiting lipopolysaccharide ...

天然物製品

Ammonium iron(III) citrate
T20819
Synonym: Ferric ammonium citrate
Target: Others, Ferroptosis
Mimosine
T6569
Synonym: Leucenine,NSC 69188,Leucenol,L-Mimosine
Target: Others
Miltirone
TN1023
Synonym:
Target: P450, GABA Receptor
Linderaspirone A
TN4441
Synonym:
Target: Others
1-Oxomiltirone
T83425
Synonym:
Target:
Dehydromiltirone
TN1562
Synonym:
Target: NOS, NF-κB, COX
Cladospirone bisepoxide
T73797
Synonym:
Target:
2-heptyl-3-hydroxy-4(1H)-Quinolone
T38373
Synonym: 2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal
Target: Others
Guanosine 5'-diphosphate
T7210
Synonym: GDP
Target: Endogenous Metabolite
Hemin
T5515
Synonym: Hemin chloride
Target: Mitophagy, Ferroptosis, Autophagy
Ginkgetin
T4S2126
Synonym:
Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy
Homobutein
TN4220
Synonym: 3-O-Methylbutein,2',4,4'-Trihydroxy-3-methoxychalcone
Target: Antioxidant, NF-κB, HDAC, Parasite, Immunology/Inflammation related
Ferroheme
T8948
Synonym: protoheme,Hematin,heme
Target: Others
Negletein
T2S0843
Synonym: 7-O-Methylbaicalein,Baicalein-7-methylether
Target: IL Receptor, TNF, NOS, Interleukin
Vitamin B12
T1040
Synonym: Cyanocobalamin,Cobalamin
Target: Endogenous Metabolite
Secoisolariciresinol diglucoside
T3415
Synonym: LGM2605
Target: ROS
4-Methyldaphnetin
TJS0315
Synonym: 7,8-Dihydroxy-4-methylcoumarin,DHMC
Target: Apoptosis, Lipoxygenase
Phytic acid potassium
T5075
Synonym: Inositol hexakisphosphate dipotassium salt,Phytic acid dipotassium salt,Fytic Acid dipotassium salt,Inositol polyphosphate dipotassium salt
Target: Others, Endogenous Metabolite
Broussochalcone A
T72594
Synonym:
Target:
Agrimonolide
TN3364
Synonym:
Target: Apoptosis, Dehydrogenase, p38 MAPK, ROS, JAK

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-03227 CISD1 Protein, Human, Recombinant (His) Human E. coli
Mitochondrial dysfunction is thought to play a significant role in neurodegeneration observed in Parkinson's disease (PD), the loss of mitoNEET (CISD1), an iron-sulfur containing protein that regulates mitochondrial bioe...
TMPH-00387 Toxin CfTX-1 Protein, Chironex fleckeri, Recombinant (His & SUMO) Chironex fleckeri E. coli
May cause profound effects on the cardiovascular system of anesthetized rats (at 25 ug/kg), since the fraction containing this toxin and CfTX-2 produces an initial increase in mean arterial pressure, followed by cardiova...
TMPY-01279 Transferrin Protein, Human, Recombinant (His) Human HEK293
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an...
TMPY-03295 Transferrin Protein, Mouse, Recombinant (His) Mouse HEK293
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an...
TMPY-03739 Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran...
TMPY-05096 Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc) Human HEK293
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran...
TMPY-02294 Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His) Mouse HEK293
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran...
TMPY-01873 Transferrin Receptor/TFRC Protein, Human, Recombinant (His) Human HEK293
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran...
TMPY-00988 Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His) Mouse HEK293
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,...
TMPY-04727 GDF-15 Protein, Human, Recombinant (His) Human Yeast
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not...
TMPY-00873 Lipocalin-2/LCN2 Protein, Human, Recombinant (His) Human HEK293
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,...
TMPY-01073 GDF-15 Protein, Human, Recombinant (hFc) Human HEK293
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not...
TMPY-02707 PAH Protein, Human, Recombinant (415 Asn/Asp, His) Human Baculovirus-Insect Cells
PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding si...
TMPH-00771 Ferritin-2 Protein, Glycine max, Recombinant (His & SUMO) Glycine max E. coli
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
TMPH-00641 YTFE Protein, E. coli, Recombinant (GST) E. coli E. coli
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
TMPJ-00761 FTH Protein, Human, Recombinant (His) Human E. coli
Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is ta...
TMPH-02460 NifH1 Protein, Methanobacterium ivanovii, Recombinant (His & Myc) Methanobacterium ivanovii E. coli
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
TMPY-00544 Transferrin Protein, Rat, Recombinant (His) Rat HEK293
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an...
TMPK-01170 Hepcidin/HAMP Protein, Mouse, Recombinant (GST) Mouse E. coli
Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of ge...
TMPY-02711 Ferritin heavy chain 1/FTH1 Protein, Human, Recombinant Human E. coli
FTH1 (ferritin, heavy polypeptide 1) is the heavy subunit of ferritin which is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin cha...
TMPH-03407 NIFH Protein, Rhizobium leguminosarum, Recombinant (GST & His & Myc) Rhizobium leguminosarum E. coli
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
TMPH-01561 ISCU Protein, Human, Recombinant (His & Myc) Human Baculovirus
Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic Functions as a cytoplasmic scaffold protein for the de...
TMPH-03505 Glutaredoxin 4/GrxD Protein, Shigella flexneri, Recombinant (His & SUMO) Shigella flexneri E. coli
Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.
TMPY-03294 Transferrin Protein, Mouse, Recombinant (hFc) Mouse HEK293
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an...
TMPY-02780 Transferrin Protein, Sus scrofa (Pig), Recombinant (hFc) Sus scrofa (Pig) HEK293
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an...
TMPY-02781 Transferrin Protein, Sus scrofa (Pig), Recombinant (His) Sus scrofa (Pig) HEK293
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an...
TMPH-02660 Frataxin/FXN Protein, Mouse, Recombinant (His) Mouse Yeast
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr...
TMPH-03295 Frataxin/FXN Protein, Rat, Recombinant Rat E. coli
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr...
TMPY-02582 Ferritin light chain Protein, Human, Recombinant (His) Human E. coli
Ferritin, light polypeptide (FTL) is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light...
TMPH-02646 Erythroferrone Protein, Mouse, Recombinant (His) Mouse Yeast
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increase...
TMPY-02482 Aconitase 1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Aconitase 1(ACO1) or IRP1 is one member of the aconitase family that contains a diverse group of iron-sulphur(Fe-S) isomerases and two types of iron regulatory protein. Aconitase exits in two forms: one is soluble and th...
TMPJ-01062 HAMP Protein, Human, Recombinant (GST) Human E. coli
Hepcidin(HAMP)is a secreted protein that belongs to the hepcidin family.It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron sto...
TMPH-02428 Frataxin Protein, Cynomolgus, Recombinant (His) Cynomolgus E. coli
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr...
TMPH-00792 FtnA Protein, Helicobacter pylori, Recombinant (His) Helicobacter pylori Baculovirus
Iron-storage protein.
TMPH-00793 FtnA Protein, Helicobacter pylori, Recombinant (E. coli, His) Helicobacter pylori E. coli
Iron-storage protein.
TMPH-00016 Ferredoxin Protein, Acetoanaerobium sticklandii, Recombinant (His & Myc) Acetoanaerobium sticklandii E. coli
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
TMPH-01356 Frataxin/FXN Protein, Human, Recombinant (His & Myc) Human E. coli
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr...
TMPY-05617 Transferrin Receptor/TFRC Protein, Human, Recombinant (His), Biotinylated Human HEK293
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran...
TMPY-06661 Transferrin Receptor/TFRC Protein, Rat, Recombinant (His) Rat HEK293
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran...
TMPJ-00378 Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His) Human Human Cells
Transferrin receptor protein 1 (TFRC) belongs to the peptidase M28 family that is synthesized as a 172 amino acid (aa). TFRC regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP...
TMPH-02661 Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His) Mouse E. coli
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr...
TMPH-01301 Erythroferrone Protein, Human, Recombinant (His & SUMO) Human E. coli
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increase...
TMPY-02426 UBE2D1 Protein, Human, Recombinant (His) Human E. coli
Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up...
TMPH-03705 NfuA Protein, Vibrio vulnificus, Recombinant Vibrio vulnificus E. coli
Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged ...
TMPH-02417 Albumin Protein, Cynomolgus, Recombinant (His & Myc) Cynomolgus HEK293
Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of...
TMPY-01770 HAO1 Protein, Human, Recombinant (His) Human E. coli
Hydroxyacid oxidase 1, also known as Glycolate oxidase, HAO1, and GOX1, is a member of the FMN-dependent alpha-hydroxy acid dehydrogenase family. HAO1 / GOX1 has 2-hydroxyacid oxidase activity. It is most active on the 2...
TMPJ-00513 LTF Protein, Human, Recombinant (His) Human Human Cells
Lactotransferrin is a member of the transferrin family that transfer iron to the cells and control the level of free iron in the blood and external secretions. Lactotransferrin is a secreted protein and contains two tran...
TMPH-00384 Vitellogenin-1 Protein, Chicken, Recombinant (His) Chicken E. coli
Precursor of the egg-yolk proteins that are sources of nutrients during early development of oviparous organisms.; Phosvitin is believed to be of importance in sequestering calcium, iron and other cations for the develop...
TMPH-03746 NfuA Protein, E. coli, Recombinant (Avi & His & MBP), Biotinylated ENT-Escherichia coli E. coli
Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged ...
TMPH-02389 Hepcidin Protein, Larimichthys crocea, Recombinant Larimichthys crocea E. coli
Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages.; Has very st...
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CISD1 Protein, Human, Recombinant (His)
TMPY-03227
Species: Human
Expression System: E. coli
Toxin CfTX-1 Protein, Chironex fleckeri, Recombinant (His & SUMO)
TMPH-00387
Species: Chironex fleckeri
Expression System: E. coli
Transferrin Protein, Human, Recombinant (His)
TMPY-01279
Species: Human
Expression System: HEK293
Transferrin Protein, Mouse, Recombinant (His)
TMPY-03295
Species: Mouse
Expression System: HEK293
Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-03739
Species: Cynomolgus,Rhesus
Expression System: HEK293
Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc)
TMPY-05096
Species: Human
Expression System: HEK293
Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His)
TMPY-02294
Species: Mouse
Expression System: HEK293
Transferrin Receptor/TFRC Protein, Human, Recombinant (His)
TMPY-01873
Species: Human
Expression System: HEK293
Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His)
TMPY-00988
Species: Mouse
Expression System: HEK293
GDF-15 Protein, Human, Recombinant (His)
TMPY-04727
Species: Human
Expression System: Yeast
Lipocalin-2/LCN2 Protein, Human, Recombinant (His)
TMPY-00873
Species: Human
Expression System: HEK293
GDF-15 Protein, Human, Recombinant (hFc)
TMPY-01073
Species: Human
Expression System: HEK293
PAH Protein, Human, Recombinant (415 Asn/Asp, His)
TMPY-02707
Species: Human
Expression System: Baculovirus-Insect Cells
Ferritin-2 Protein, Glycine max, Recombinant (His & SUMO)
TMPH-00771
Species: Glycine max
Expression System: E. coli
YTFE Protein, E. coli, Recombinant (GST)
TMPH-00641
Species: E. coli
Expression System: E. coli
FTH Protein, Human, Recombinant (His)
TMPJ-00761
Species: Human
Expression System: E. coli
nifH1 Protein, Methanobacterium ivanovii, Recombinant (His & Myc)
TMPH-02460
Species: Methanobacterium ivanovii
Expression System: E. coli
Transferrin Protein, Rat, Recombinant (His)
TMPY-00544
Species: Rat
Expression System: HEK293
Hepcidin/HAMP Protein, Mouse, Recombinant (GST)
TMPK-01170
Species: Mouse
Expression System: E. coli
Ferritin heavy chain 1/FTH1 Protein, Human, Recombinant
TMPY-02711
Species: Human
Expression System: E. coli
NIFH Protein, Rhizobium leguminosarum, Recombinant (GST & His & Myc)
TMPH-03407
Species: Rhizobium leguminosarum
Expression System: E. coli
ISCU Protein, Human, Recombinant (His & Myc)
TMPH-01561
Species: Human
Expression System: Baculovirus
Glutaredoxin 4/GrxD Protein, Shigella flexneri, Recombinant (His & SUMO)
TMPH-03505
Species: Shigella flexneri
Expression System: E. coli
Transferrin Protein, Mouse, Recombinant (hFc)
TMPY-03294
Species: Mouse
Expression System: HEK293
Transferrin Protein, Sus scrofa (Pig), Recombinant (hFc)
TMPY-02780
Species: Sus scrofa (Pig)
Expression System: HEK293
Transferrin Protein, Sus scrofa (Pig), Recombinant (His)
TMPY-02781
Species: Sus scrofa (Pig)
Expression System: HEK293
Frataxin/FXN Protein, Mouse, Recombinant (His)
TMPH-02660
Species: Mouse
Expression System: Yeast
Frataxin/FXN Protein, Rat, Recombinant
TMPH-03295
Species: Rat
Expression System: E. coli
Ferritin light chain Protein, Human, Recombinant (His)
TMPY-02582
Species: Human
Expression System: E. coli
Erythroferrone Protein, Mouse, Recombinant (His)
TMPH-02646
Species: Mouse
Expression System: Yeast
Aconitase 1 Protein, Human, Recombinant (His)
TMPY-02482
Species: Human
Expression System: Baculovirus-Insect Cells
HAMP Protein, Human, Recombinant (GST)
TMPJ-01062
Species: Human
Expression System: E. coli
Frataxin Protein, Cynomolgus, Recombinant (His)
TMPH-02428
Species: Cynomolgus
Expression System: E. coli
FtnA Protein, Helicobacter pylori, Recombinant (His)
TMPH-00792
Species: Helicobacter pylori
Expression System: Baculovirus
FtnA Protein, Helicobacter pylori, Recombinant (E. coli, His)
TMPH-00793
Species: Helicobacter pylori
Expression System: E. coli
Ferredoxin Protein, Acetoanaerobium sticklandii, Recombinant (His & Myc)
TMPH-00016
Species: Acetoanaerobium sticklandii
Expression System: E. coli
Frataxin/FXN Protein, Human, Recombinant (His & Myc)
TMPH-01356
Species: Human
Expression System: E. coli
Transferrin Receptor/TFRC Protein, Human, Recombinant (His), Biotinylated
TMPY-05617
Species: Human
Expression System: HEK293
Transferrin Receptor/TFRC Protein, Rat, Recombinant (His)
TMPY-06661
Species: Rat
Expression System: HEK293
Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His)
TMPJ-00378
Species: Human
Expression System: Human Cells
Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His)
TMPH-02661
Species: Mouse
Expression System: E. coli
Erythroferrone Protein, Human, Recombinant (His & SUMO)
TMPH-01301
Species: Human
Expression System: E. coli
UBE2D1 Protein, Human, Recombinant (His)
TMPY-02426
Species: Human
Expression System: E. coli
NfuA Protein, Vibrio vulnificus, Recombinant
TMPH-03705
Species: Vibrio vulnificus
Expression System: E. coli
Albumin Protein, Cynomolgus, Recombinant (His & Myc)
TMPH-02417
Species: Cynomolgus
Expression System: HEK293
HAO1 Protein, Human, Recombinant (His)
TMPY-01770
Species: Human
Expression System: E. coli
LTF Protein, Human, Recombinant (His)
TMPJ-00513
Species: Human
Expression System: Human Cells
Vitellogenin-1 Protein, Chicken, Recombinant (His)
TMPH-00384
Species: Chicken
Expression System: E. coli
NfuA Protein, E. coli, Recombinant (Avi & His & MBP), Biotinylated
TMPH-03746
Species: ENT-Escherichia coli
Expression System: E. coli
Hepcidin Protein, Larimichthys crocea, Recombinant
TMPH-02389
Species: Larimichthys crocea
Expression System: E. coli
カタログ番号 製品名
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779 compounds
A unique collection of 779 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study;
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A unique collection of 514 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);