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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T8132 | Iron sucrose | Iron saccharate,Sucroferric oxyhydroxide | Reactive Oxygen Species |
Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia. | |||
T0001 | Iron(II) fumarate | Ferrous fumarate,Iron Fumarate | Others |
Iron(II) fumarate (Iron Fumarate) is the iron(II) salt of fumaric acid, a reddish-orange powder, applied to supply iron intake. | |||
T9624 | iron chloride hexahydrate | ||
iron chloride hexahydrate promoted selective hydroxylation and chlorination of benzyl ketone derivatives for the construction of hetero-quaternary scaffolds. | |||
T35378 | Iron (III) hexacyanoferrate (II) | Prussian Blue,Berlin blue,Iron (III) hexacyanoferrate (II) | Others |
Iron (III) hexacyanoferrate (II) is a useful organic compound for research related to life sciences. The catalog number is T35378 and the CAS number is 14038-43-8. | |||
T4505 | Ferrous Bisglycinate | Bisglycine iron(II) salt,Iron(II) bisglycinate | Estrogen/progestogen Receptor |
Ferrous Bisglycinate (Bisglycine iron(II) salt) is used in the fortification of infant formulations and foods. | |||
T32193 | Iron sorbitex | Jectofer,Yectofer,Iron Sorbitol,HSDB 1967,Astra 1572 | |
Iron Sorbitex is used for the treatment of Iron Sorbitex deficiency anemia in patients with chronic kidney disease. Iron Sorbitex can be used as an Iron Sorbitex replacement product used for the treatment of Iron Sorbite... | |||
T35995 | Ferrichrome (iron-free) | ||
Ferrichrome (iron-free) is a hydroxamate siderophore produced by various fungi (including U. sphaerogena) that facilitates iron chelation and uptake by these organisms and is also used by bacteria as a heterologous sider... | |||
T35360 | Iron Dextran | INFeD,Conferon,Fe dextran,Fero Gradumet | Others |
Iron Dextran is a useful organic compound for research related to life sciences. The catalog number is T35360 and the CAS number is 9004-66-4. | |||
T13692 | Ferric maltol | Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate | Others |
Ferric maltol (Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate) is a ferric, non-salt-based oral iron formulation demonstrating improved tolerance in patients with previous intolerance to other iron formulations. | |||
T37851 | Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) | ||
Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) is an inducer of ferroptosis.1 It induces ferroptosis, but not apoptosis or necroptosis, in NB1 cancer cells when used at a concentration of 3 μM.1 Chlorido[N,N... | |||
T31786 | Ferumoxytol | Magnetic Black,Black Iron BM,Magnetic oxide,Black Gold F 89,11557 Black | Others |
Ferumoxytol (Magnetic Black) is a non-gadolinium based contrast agent for use in magnetic resonance imaging applications. | |||
T66117 | Iron(II) sulfate heptahydrate | ||
Iron(II) sulfate heptahydrate is a useful organic compound for research related to life sciences and the catalog number is T66117. | |||
T11064 | DMT1 blocker 2 | Others | |
DMT1 blocker 2, compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 hydrogen peroxide value of 0.83, which is expected to block iron uptake by intestinal epithelial cells in vivo. | |||
T8533 | ML318 | Others , Antibiotic | |
ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of... | |||
T8500 | VLX600 | OXPHOS , Mitochondrial Metabolism , Autophagy | |
VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent. It acts by reducing mitochondrial oxidative phosphorylation in tumor cells. | |||
T9627 | PHD-1-IN-1 | HIF/HIF Prolyl-Hydroxylase | |
PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM). | |||
T50099 | HIF-2α-IN-4 | Others , HIF/HIF Prolyl-Hydroxylase | |
HIF-2a translation inhibitor is a compound used as a molecular building block. | |||
T1457 | Deferasirox | ICL 670,CGP-72670 | Others , Ferroptosis , Antibacterial |
Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload. | |||
T19692 | Deferitrin | GT 56252,GT 56 252,GT-56252,GT-56-252 | Others |
Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload. | |||
T13396 | Zinc Protoporphyrin | Zinc Protoporphyrin-9,ZnPP,Zn(II)-protoporphyrin IX | Apoptosis , Reactive Oxygen Species , Endogenous Metabolite |
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive inhibitor of heme oxygenase-1 (HO-1) and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2, and has anti-can... | |||
T64977 | Naphthol green B | ||
Naphthol green B is a useful organic compound for research related to life sciences. The catalog number is T64977 and the CAS number is 19381-50-1. | |||
T71138L | Binospirone | MDL 73005EF | 5-HT Receptor |
Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of glaucoma and movement disorders associated with neurologic dysfunction. | |||
T68172 | Zalospirone | 5-HT Receptor | |
Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder. | |||
T2132 | Buspirone hydrochloride | Buspirone HCl,Narol,Buspar | Dopamine Receptor , 5-HT Receptor |
Buspirone hydrochloride (Buspar) is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD). | |||
T22871 | Ipsapirone | 5-HT Receptor | |
Ipsapirone is a partial agonist of 5-HT1A receptor and produces an inhibitory effect on 5-HT2 and the α1-adrenergic function at high doses. | |||
T8136 | Perospirone hydrochloride | Perospirone HCl,SM-9018 hydrochloride | Dopamine Receptor , 5-HT Receptor |
Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist. | |||
T21011 | Buspirone | Buspirone free base,Ansial | 5-HT Receptor |
Buspirone (Buspirone free base) is an azaspiro compound which has a role as an anxiolytic drug, a sedative, a serotonergic agonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor. | |||
T3179 | Eptapirone | F 11440 | 5-HT Receptor |
Eptapirone (F 11440) is a highly effective and selective 5-HT1A receptor agonist with marked antidepressant and anxiolytic potential. | |||
T7412 | Tandospirone citrate | SM-3997 citrate | 5-HT Receptor |
Tandospirone citrate (SM-3997 citrate) is a potent and selective 5-HT1A receptor partial agonist (Ki : 27 nM) | |||
T67961 | Safironil | Others | |
safironil is a novel antifibrotic compound and a competitive inhibitor of collagen synthesis. safironil inhibited in vitro experiments on fibroblast activation monitored by collagen I mRNA or smooth muscle alpha-actin le... | |||
T0476 | Spironolactone | SC9420,Abbolactone | Glucocorticoid Receptor , Androgen Receptor , Autophagy |
Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist. | |||
T24885L | Tiaspirone hydrochloride | BMY-13859 hydrochloride,Tiaspirone hydrochloride(87691-91-6 Free base) | Dopamine Receptor , 5-HT Receptor |
Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity. Tiaspirone hydrochloride influences the electrophysiological activity of dopaminergic neurons in the substantia nigra zona compacta (A9 ... | |||
T24885 | Tiospirone | BMY 13859-1 | Dopamine Receptor , 5-HT Receptor |
Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and dopamine blocker that inhibits D2, 5-HT1a, 5-HT7, and sigma receptors.Tiospirone is used in the study of neurological disorders such as schizophrenia. | |||
T4576 | Perospirone | Lullan | Dopamine Receptor , 5-HT Receptor |
Perospirone (Lullan) is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist. | |||
T28827 | Sofpironium bromide | BBI4000,BBI 4000,BBI-4000 | Others , AChR |
Sofpironium bromide (BBI4000) belongs to a class of drugs called anticholinergics, which exert their effect by blocking the action of acetylcholine. | |||
T19917 | Gepirone | 5-HT Receptor | |
Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs. | |||
T24923 | Umespirone | Umespirona,Umespironum | |
Umespirone is a potential antipsychotic/anxiolytic drug of the azapirone class. It possesses anxiolytic and antipsychotic properties. | |||
T30179 | Astiron | Astyron | |
Astiron is a self-expanding bare-metal nitinol stent. | |||
T29480 | 7alpha-Thiospironolactone | Deacetylspironolactone | |
7α-Thio Spironolactone is a Spironolactone (sc-204294) metabolite. | |||
T26709 | Azadirone | ||
Azadirone is a limonoid tetranortriterpene. Azadirone can sensitize cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through ROS-ERK-CHOP-mediated up-regulation of DR4 and DR5 signaling, do... | |||
T69038 | Teroxirone | ||
Teroxirone, also known as Triglycidyl Isocyanurate and Tris(2,3-epoxypropyl) Isocyanurate, is a triazene triepoxide with antineoplastic activity. Teroxine alkylates and cross-links DNA, thereby inhibiting DNA replicatio... | |||
T70666 | Alnespirone hydrochloride | ||
Alnespirone hydrochloride is a selective 5-HT1A receptor full agonist of the azapirone chemical class. It has both antidepressant and anxiolytic effects. | |||
T16543 | Pironetin | Microtubule Associated | |
Pironetin binds to α-tubulin and is an effective inhibitor of microtubule polymerization. It also has cell cycle arrest and antitumor activity. Pironetin is an α/β unsaturated lactone isolated from Streptomyces species. | |||
T70814 | Alnespirone | ||
Alnespirone, also known as S-20499, is a selective 5-HT1A receptor full agonist of the azapirone chemical class. It has both antidepressant and anxiolytic effects. | |||
T69034 | Enilospirone | ||
Enilospirone is a selective 5-HT1A receptor agonist of the azapirone class. | |||
T9163 | IRONE | Others | |
Irone is used as a fragrance ingredient. | |||
T68715 | Anaxirone | ||
Anaxirone is a synthetic triepoxide alkylating agent with potential antineoplastic activity. Anaxirone alkylates DNA via actual or derived epoxide groups, resulting in inhibition of DNA synthesis. This agent has been sho... | |||
TQ0315 | Tandospirone | SM-3997 | 5-HT Receptor |
Tandospirone (SM-3997) is a selective partial agonist of 5-HT1A receptor (Ki: 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Kis: 1300-41000 nM). | |||
T34887 | Tiron free acid | ||
Tiron free acid is a bioactive chemical. | |||
T125947 | Amorphispironone | ||
Amorphispironone is a useful organic compound for research related to life sciences. The catalog number is T125947 and the CAS number is 139006-28-3. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T20819 | Ammonium iron(III) citrate | Ferric ammonium citrate | Others , Ferroptosis |
Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload leading to cellular iron death and enhances protein production. | |||
T6569 | Mimosine | Leucenine,NSC 69188,Leucenol,L-Mimosine | Others |
L-Mimosine (Leucenol) is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator. | |||
TN1023 | Miltirone | P450 , GABA Receptor | |
Miltirone is a CYPs inhibitor, it has been characterized as a low-affinity ligand for central benzodiazepine receptors. | |||
TN4441 | Linderaspirone A | Others | |
Linderaspirone A shows significant activity against glucosamine-inducedinsulin resistance. | |||
T83425 | 1-Oxomiltirone | ||
2-Isopropyl-8,8-dimethyl-7,8-dihydrophenanthrene-3,4,5(6H)-trione, a C20-norabietane diterpenoid exhibiting anti-inflammatory properties, is isolated from sage leaves [1]. | |||
TN1562 | Dehydromiltirone | NOS , NF-κB , COX | |
Dehydromiltirone has antioxidant activity, it shows significant anti-neuroinflammatory effects through inhibiting PI3K/Akt phosphorylation and then inhibiting NF-κB signaling pathway. | |||
T73797 | Cladospirone bisepoxide | ||
Cladospirone bisepoxide, a metabolite isolated from fungal cultures, exhibits selective antibiotic activity against various bacteria and fungi, and at low concentrations, it inhibits the germination of Lepidium sativum [... | |||
T38373 | 2-heptyl-3-hydroxy-4(1H)-Quinolone | 2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal | Others |
2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) is a quorum-sensing signalling molecule produced by Pseudomonas aeruginosa in response to increased cell density. It increases the expression of the lasB ... | |||
T7210 | Guanosine 5'-diphosphate | GDP | Endogenous Metabolite |
Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. | |||
T5515 | Hemin | Hemin chloride | Mitophagy , Ferroptosis , Autophagy |
Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer. Hemin has therapeutic activity in porphyrias by reducing heme deficiency in patients, thereby inhibiting δ-aminolevulini... | |||
T4S2126 | Ginkgetin | Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy | |
1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ... | |||
TN4220 | Homobutein | 3-O-Methylbutein,2',4,4'-Trihydroxy-3-methoxychalcone | Antioxidant , NF-κB , HDAC , Parasite , Immunology/Inflammation related |
T8948 | Ferroheme | protoheme,Hematin,heme | Others |
Ferroheme (protoheme) is the color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins. A Ferroheme or haem is a prosthetic group that consists of an iron atom c... | |||
T2S0843 | Negletein | 7-O-Methylbaicalein,Baicalein-7-methylether | IL Receptor , TNF , NOS , Interleukin |
1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n... | |||
T1040 | Vitamin B12 | Cyanocobalamin,Cobalamin | Endogenous Metabolite |
Cyanocobalamin is a cobalt-containing coordination compound generated by intestinal microbes and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intes... | |||
T3415 | Secoisolariciresinol diglucoside | LGM2605 | ROS |
Secoisolariciresinol diglucoside (LGM2605) was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol diglucoside (25 mg/kg b.w.) exerts the antihyperglycemic effect ... | |||
TJS0315 | 4-Methyldaphnetin | 7,8-Dihydroxy-4-methylcoumarin,DHMC | Apoptosis , Lipoxygenase |
4-Methyldaphnetin (DHMC) is a potent inhibitor (low micromolar) of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals, but may be pro-oxidant (enhancing generation of hydr... | |||
T5075 | Phytic acid potassium | Inositol hexakisphosphate dipotassium salt,Phytic acid dipotassium salt,Fytic Acid dipotassium salt,Inositol polyphosphate dipotassium salt | Others , Endogenous Metabolite |
Phytic acid potassium (Inositol polyphosphate dipotassium salt) exists in all eukaryotic cells. In plants, it is known to function as a [PO4]3 storage depot and precursor for other inositol phosphates and pyrophosphates.... | |||
T72594 | Broussochalcone A | ||
Broussochalcone A, an antioxidant and Xanthine Oxidase inhibitor (IC 50 =2.21 μM), exhibits free radical scavenging activity. It prevents iron-induced lipid peroxidation and nitric oxide synthesis in lipopolysaccharide (... | |||
TN3364 | Agrimonolide | Apoptosis , Dehydrogenase , p38 MAPK , ROS , JAK | |
Agrimonolide, a compound derived from isocoumarins and found mainly in the herb Agrimonia pilosa Ledeb, has significant biological activity. agrimonolide exerts anti-inflammatory effects by inhibiting lipopolysaccharide ... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-03227 | CISD1 Protein, Human, Recombinant (His) | Human | E. coli |
Mitochondrial dysfunction is thought to play a significant role in neurodegeneration observed in Parkinson's disease (PD), the loss of mitoNEET (CISD1), an iron-sulfur containing protein that regulates mitochondrial bioe... | |||
TMPH-00387 | Toxin CfTX-1 Protein, Chironex fleckeri, Recombinant (His & SUMO) | Chironex fleckeri | E. coli |
May cause profound effects on the cardiovascular system of anesthetized rats (at 25 ug/kg), since the fraction containing this toxin and CfTX-2 produces an initial increase in mean arterial pressure, followed by cardiova... | |||
TMPY-01279 | Transferrin Protein, Human, Recombinant (His) | Human | HEK293 |
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an... | |||
TMPY-03295 | Transferrin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an... | |||
TMPY-03739 | Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 |
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran... | |||
TMPY-05096 | Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc) | Human | HEK293 |
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran... | |||
TMPY-02294 | Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran... | |||
TMPY-01873 | Transferrin Receptor/TFRC Protein, Human, Recombinant (His) | Human | HEK293 |
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran... | |||
TMPY-00988 | Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,... | |||
TMPY-04727 | GDF-15 Protein, Human, Recombinant (His) | Human | Yeast |
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not... | |||
TMPY-00873 | Lipocalin-2/LCN2 Protein, Human, Recombinant (His) | Human | HEK293 |
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,... | |||
TMPY-01073 | GDF-15 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not... | |||
TMPY-02707 | PAH Protein, Human, Recombinant (415 Asn/Asp, His) | Human | Baculovirus-Insect Cells |
PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding si... | |||
TMPH-00771 | Ferritin-2 Protein, Glycine max, Recombinant (His & SUMO) | Glycine max | E. coli |
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. | |||
TMPH-00641 | YTFE Protein, E. coli, Recombinant (GST) | E. coli | E. coli |
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions. | |||
TMPJ-00761 | FTH Protein, Human, Recombinant (His) | Human | E. coli |
Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is ta... | |||
TMPH-02460 | NifH1 Protein, Methanobacterium ivanovii, Recombinant (His & Myc) | Methanobacterium ivanovii | E. coli |
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein. | |||
TMPY-00544 | Transferrin Protein, Rat, Recombinant (His) | Rat | HEK293 |
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an... | |||
TMPK-01170 | Hepcidin/HAMP Protein, Mouse, Recombinant (GST) | Mouse | E. coli |
Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of ge... | |||
TMPY-02711 | Ferritin heavy chain 1/FTH1 Protein, Human, Recombinant | Human | E. coli |
FTH1 (ferritin, heavy polypeptide 1) is the heavy subunit of ferritin which is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin cha... | |||
TMPH-03407 | NIFH Protein, Rhizobium leguminosarum, Recombinant (GST & His & Myc) | Rhizobium leguminosarum | E. coli |
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein. | |||
TMPH-01561 | ISCU Protein, Human, Recombinant (His & Myc) | Human | Baculovirus |
Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic Functions as a cytoplasmic scaffold protein for the de... | |||
TMPH-03505 | Glutaredoxin 4/GrxD Protein, Shigella flexneri, Recombinant (His & SUMO) | Shigella flexneri | E. coli |
Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. | |||
TMPY-03294 | Transferrin Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an... | |||
TMPY-02780 | Transferrin Protein, Sus scrofa (Pig), Recombinant (hFc) | Sus scrofa (Pig) | HEK293 |
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an... | |||
TMPY-02781 | Transferrin Protein, Sus scrofa (Pig), Recombinant (His) | Sus scrofa (Pig) | HEK293 |
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an... | |||
TMPH-02660 | Frataxin/FXN Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr... | |||
TMPH-03295 | Frataxin/FXN Protein, Rat, Recombinant | Rat | E. coli |
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr... | |||
TMPY-02582 | Ferritin light chain Protein, Human, Recombinant (His) | Human | E. coli |
Ferritin, light polypeptide (FTL) is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light... | |||
TMPH-02646 | Erythroferrone Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increase... | |||
TMPY-02482 | Aconitase 1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Aconitase 1(ACO1) or IRP1 is one member of the aconitase family that contains a diverse group of iron-sulphur(Fe-S) isomerases and two types of iron regulatory protein. Aconitase exits in two forms: one is soluble and th... | |||
TMPJ-01062 | HAMP Protein, Human, Recombinant (GST) | Human | E. coli |
Hepcidin(HAMP)is a secreted protein that belongs to the hepcidin family.It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron sto... | |||
TMPH-02428 | Frataxin Protein, Cynomolgus, Recombinant (His) | Cynomolgus | E. coli |
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr... | |||
TMPH-00792 | FtnA Protein, Helicobacter pylori, Recombinant (His) | Helicobacter pylori | Baculovirus |
Iron-storage protein. | |||
TMPH-00793 | FtnA Protein, Helicobacter pylori, Recombinant (E. coli, His) | Helicobacter pylori | E. coli |
Iron-storage protein. | |||
TMPH-00016 | Ferredoxin Protein, Acetoanaerobium sticklandii, Recombinant (His & Myc) | Acetoanaerobium sticklandii | E. coli |
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | |||
TMPH-01356 | Frataxin/FXN Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr... | |||
TMPY-05617 | Transferrin Receptor/TFRC Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran... | |||
TMPY-06661 | Transferrin Receptor/TFRC Protein, Rat, Recombinant (His) | Rat | HEK293 |
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran... | |||
TMPJ-00378 | Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His) | Human | Human Cells |
Transferrin receptor protein 1 (TFRC) belongs to the peptidase M28 family that is synthesized as a 172 amino acid (aa). TFRC regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP... | |||
TMPH-02661 | Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr... | |||
TMPH-01301 | Erythroferrone Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increase... | |||
TMPY-02426 | UBE2D1 Protein, Human, Recombinant (His) | Human | E. coli |
Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up... | |||
TMPH-03705 | NfuA Protein, Vibrio vulnificus, Recombinant | Vibrio vulnificus | E. coli |
Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged ... | |||
TMPH-02417 | Albumin Protein, Cynomolgus, Recombinant (His & Myc) | Cynomolgus | HEK293 |
Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of... | |||
TMPY-01770 | HAO1 Protein, Human, Recombinant (His) | Human | E. coli |
Hydroxyacid oxidase 1, also known as Glycolate oxidase, HAO1, and GOX1, is a member of the FMN-dependent alpha-hydroxy acid dehydrogenase family. HAO1 / GOX1 has 2-hydroxyacid oxidase activity. It is most active on the 2... | |||
TMPJ-00513 | LTF Protein, Human, Recombinant (His) | Human | Human Cells |
Lactotransferrin is a member of the transferrin family that transfer iron to the cells and control the level of free iron in the blood and external secretions. Lactotransferrin is a secreted protein and contains two tran... | |||
TMPH-00384 | Vitellogenin-1 Protein, Chicken, Recombinant (His) | Chicken | E. coli |
Precursor of the egg-yolk proteins that are sources of nutrients during early development of oviparous organisms.; Phosvitin is believed to be of importance in sequestering calcium, iron and other cations for the develop... | |||
TMPH-03746 | NfuA Protein, E. coli, Recombinant (Avi & His & MBP), Biotinylated | ENT-Escherichia coli | E. coli |
Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged ... | |||
TMPH-02389 | Hepcidin Protein, Larimichthys crocea, Recombinant | Larimichthys crocea | E. coli |
Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages.; Has very st... | |||
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A unique collection of 779 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study; | |||
L8710 | Cuproptosis Compound Library | 400 compounds | |
TargetMol’s Cuproptosis Compound Library is a collection of 400 compounds related to copper-dependent death that can be used to study its mechanism and related diseases. | |||
L8400 | Hematonosis Compound Library | 514 compounds | |
A unique collection of 514 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS); |