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カタログ番号 | 製品名 | 別名 | ターゲット |
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T39334 | Remdesivir nucleoside monophosphate | ||
Remdesivir nucleoside monophosphate, a metabolite of Remdesivir, is a potent antiviral compound with nucleoside analogue characteristics. It exhibits effective antiviral activity against both SARS-CoV and MERS-CoV. | |||
T24385 | L-Acosamine nucleoside | ||
L-Acosamine nucleoside has antiviral activity against HIV and HSV-1. | |||
T19486 | Nucleoside-Analog-2 | Others | |
Nucleoside-Analog-2 is a 4'-Azidocytidine analogue, used to against Hepatitis C virus (HCV) replication. | |||
T25759 | L-Ristosamine nucleoside | ||
L-Ristosamine nucleoside shows antiviral activity. | |||
T19485 | Nucleoside-Analog-1 | Others | |
Nucleoside-Analog-1 is a 4′-Azidocytidine analogue, used to against Hepatitis C virus replication. | |||
T76096 | Purine nucleoside phosphorylase | ||
Purine Nucleoside Phosphorylase, an essential enzyme in purine metabolism, plays a critical role in the purine salvage pathway. Its deficiency impairs T cell function. With inorganic orthophosphate as a co-substrate, thi... | |||
T6065 | Triciribine | VD-0002,Tricyclic nucleoside,NSC 154020,API-2,TCN | Akt , HIV Protease , DNA/RNA Synthesis |
Triciribine (NSC-154020) is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2. | |||
T75409 | Nucleoside hydrolase (IAGNH) | ||
Nucleoside hydrolase (IAGNH), a type of glycosidase, facilitates the recycling of nucleobases and ribose by catalyzing the cleavage of the N-glycosidic bond in nucleosides. | |||
TNU1281 | P-2'-deoxyribose | 6-(β-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one,P-Nucleoside | Others |
P-2'-deoxyribose (P-Nucleoside) is a deoxyribose that is widely found in organisms. | |||
T8354 | Triazavirin | Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis | |
Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent. | |||
T9727 | 2'-Fluoro-2'-Deoxyadenosine | Nucleoside Antimetabolite/Analog | |
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors ex... | |||
T7351 | 3-Methylcytidine | Nucleoside Antimetabolite/Analog | |
3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer. | |||
T0297 | Clofarabine | Clofarex,Evoltra,Clolar | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Autophagy |
Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase. | |||
T13621 | CNDAC hydrochloride | Nucleoside Antimetabolite/Analog , Others , Drug Metabolite | |
CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine. | |||
T7491 | 6-O-Methyl Guanosine | Nucleoside Antimetabolite/Analog | |
6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line. | |||
T12399 | Peldesine | BCX 34 | Nucleoside Antimetabolite/Analog , HIV Protease |
T9726 | 2’-OMe-Guanosine | Apoptosis , Nucleoside Antimetabolite/Analog | |
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect. | |||
T15235 | Enocitabine | Nucleoside Antimetabolite/Analog , HCV Protease , DNA/RNA Synthesis | |
Enocitabine is a nucleoside analog. Enocitabine inhibits the replication of human cytomegalovirus(HCMV) and it also has antileukemic and antiviral activities. Enocitabine is also a potent DNA replication inhibitor and a ... | |||
T38237 | 2′-O-Methylcytidine | Nucleoside Antimetabolite/Analog , HCV Protease | |
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replication in a replicon assay (IC50= 21.2 μM). 1.Migliaccio, G.... | |||
T9103 | BVDV-IN-1 | DNA/RNA Synthesis | |
BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp. It has antiviral activity against BVDV resistant to... | |||
T13659 | DMTr-LNA-5MeU-3-CED-phosphoramidite | Nucleoside Antimetabolite/Analog | |
DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside. | |||
T3658 | Trifluridine/tipiracil hydrochloride mixture | Trifluridine-tipiracil hydrochloride mixture,TAS102,TAS-102,TAS 102 | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a molar ratio of 2:1. | |||
T38238 | 2'-Deoxy-2'-fluorocytidine | Nucleoside Antimetabolite/Analog , Influenza Virus | |
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency o... | |||
T1404 | Stavudine | d4T,Sanilvudine,BMY-27857,NSC 163661 | Apoptosis , Nucleoside Antimetabolite/Analog , HIV Protease , NOD-like Receptor (NLR) , Reverse Transcriptase , Autophagy |
Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV. | |||
T7518 | Deoxycytidine triphosphate trisodium salt | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Antibiotic |
Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria. | |||
T1307 | Carmofur | HCFU | Nucleoside Antimetabolite/Analog , Virus Protease , SARS-CoV , DNA/RNA Synthesis |
Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy. | |||
T36756 | DMT-dG(ib) Phosphoramidite | DNA/RNA Synthesis | |
DMT-dG(ib) Phosphoramidite can be used to synthesize DNA. | |||
T8648 | 6-AZATHYMINE | Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis , Antibacterial | |
6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic... | |||
T38236 | 2′-Deoxy-2′-fluoroguanosine | Nucleoside Antimetabolite/Analog , Influenza Virus | |
2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhibitor of influenza virus replication in the upper respirator... | |||
T19464 | N6,N6-Dimethyladenosine | Nucleoside Antimetabolite/Analog | |
N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA. | |||
T40686 | Tiazofurin | NSC 286193,Riboxamide | Dehydrogenase |
Tiazofurin (NSC-286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent IMP dehydrogenase (IMPDH) in... | |||
T4061 | LY2334737 | Nucleoside Antimetabolite/Analog , Others , Virus Protease | |
LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity. | |||
T16911 | Sorivudine | BV-araU | DNA/RNA Synthesis |
Sorivudine (BV-araU) has antiviral activity against several viruses including varicella zoster virus, herpes simplex type 1 virus, and Epstein-Barr virus by interfering with viral DNA synthesis. | |||
T38958 | DMT-2′Fluoro-dU Phosphoramidite | 2'-F-dU Phosphoramidite | Nucleoside Antimetabolite/Analog |
DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides. | |||
T10066 | 2',5'-Dideoxyadenosine | Adenylyl cyclase , Adrenergic Receptor , AChR | |
2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site (IC50: 3 μM). | |||
T2366 | Tipiracil hydrochloride | MA-1 hydrochloride | Nucleoside Antimetabolite/Analog |
Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI). Tipiracil hydrochloride is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical t... | |||
T7621 | 6-Thioinosine | 6-Mercaptopurine riboside,6TI | Nucleoside Antimetabolite/Analog |
6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent. | |||
T6446 | Clevudine | L-FMAU,Levovir | HBV , DNA/RNA Synthesis |
Clevudine (Levovir) is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The ... | |||
T1120 | Dacarbazine | Imidazole Carboxamide,DTIC-Dome | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas. | |||
T1408 | Capecitabine | Xeloda,Capecitibine,Capiibine,RO 09-1978 | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moie... | |||
T6603 | Nelarabine | GW 506U78,Nelzarabine,506U78 | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells. | |||
T0075 | Nicorandil | SG-75 | Potassium Channel |
Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system. It undertakes this through two methods. Firstly, by activating potassium channels, and secondly b... | |||
T0251 | Gemcitabine | NSC 613327,LY188011 | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Autophagy |
Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis. | |||
T6729 | Lomibuvir | VX-222,VCH-222 | HCV Protease |
Lomibuvir (VCH-222) (VX-222) is a selective, non-nucleoside allosteric inhibitor of HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC 50 of 5.2 nM. Lomibuvir... | |||
T0010 | 6-Mercaptopurine | 6-MP,Mercaptopurine | Nucleoside Antimetabolite/Analog , Others , Dehydrogenase , Endogenous Metabolite , Autophagy |
6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with othe... | |||
T1646 | Famciclovir | BRL 42810 | DNA/RNA Synthesis , HSV |
Famciclovir (BRL 42810) is a Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of famciclovir is as a DNA Polymerase Inhibitor, and DNA Polymerase Inhibitor. | |||
T1378 | Tegafur | Fluorafur,FT-207,NSC 148958,FT 207 | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity. Tegafur is a prodrug that is gradually converted to fluorouracil in the liver by the cytochrome P-450 enzyme. | |||
T16813 | RX-3117 | fluorocyclopentenylcytosine,TV-1360 | Nucleoside Antimetabolite/Analog |
RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog. RX-3117 displays anticancer activity in several cancer cell lines, including gemcitabine-resistant variants. | |||
T40192 | DGTP | 2'-Deoxyguanosine-5'-triphosphate | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP. | |||
T6794 | 5-BrdU | BUdR,Broxuridine,5-bromo-2'-deoxyuridine,Bromodeoxyuridine,BRDU | Nucleoside Antimetabolite/Analog , Others |
5-BrdU (Broxuridine) , a nucleoside analog, are used in the detection of proliferating cells and competes with thymidine for incorporation into DNA. |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T16674 | Pseudouridine | Endogenous Metabolite | |
Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure. | |||
T7520 | Deoxycytidine triphosphate | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite | |
Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing. | |||
T5912 | 5-Methylcytidine | Endogenous Metabolite | |
5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA as well as DNA for certain organisms. | |||
T7319 | 7-Methylguanosine | Nucleoside Antimetabolite/Analog , Endogenous Metabolite | |
7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor (IC50 : 87.8 ± 7.5 μM). | |||
T19382 | Isoguanine | Nucleoside Antimetabolite/Analog | |
Isoguanine is a purine base that is an isomer of guanine. A building block in organic synthesis. | |||
T9605 | Sangivamycin | BA-90912,NSC 65346 | Nucleoside Antimetabolite/Analog , PKC |
Sangivamycin (NSC-65346) is an effective inhibitor of protein kinase C (PKC, Ki = 10 μM). Sangivamycin exhibits antiproliferative activity against a variety of human cancers. | |||
T1591L | Cytidine | Cytosine-1-β-D-ribofuranoside,Cytosine β-D-riboside | Nucleoside Antimetabolite/Analog , Endogenous Metabolite |
Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precursor for uridine. Both cytidine and uridine are utilized in RN... | |||
T7514 | N2-Methylguanosine | Nucleoside Antimetabolite/Analog , Endogenous Metabolite | |
N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA's | |||
T2221 | Uridine | Uridin,β-Uridine,NSC 20256 | Others , Endogenous Metabolite |
Uridine (Uridin), a nucleoside, consists of uracil and D-ribose by a β-N1-glycosidic bond. | |||
T0853 | Adenosine | D-Adenosine,Adenine riboside | Apoptosis , Nucleoside Antimetabolite/Analog , Endogenous Metabolite , Autophagy |
Adenosine (D-Adenosine) is a ribonucleoside comprised of adenine bound to ribose, with vasodilatory, antiarrhythmic and analgesic activities. | |||
T19083 | 1-Methylinosine | N1-Methylinosine,Inosine, 1-methyl | Nucleoside Antimetabolite/Analog , Endogenous Metabolite |
1-Methylinosine (N1-Methylinosine) is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA and has a role as a metabolite. | |||
T0437 | Inosine | INO 495,NSC 20262 | ROS , Endogenous Metabolite , Adenosine Receptor |
Inosine (NSC-20262) is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It has immunomodulatory, neuroprotective, and analgesic properties. | |||
T0746 | Orotic acid | Vitamin B13,6-Carboxyuracil | Nucleoside Antimetabolite/Analog , Dehydrogenase , Endogenous Metabolite |
Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism. | |||
T9086 | Deoxythymidine-5'-triphosphate trisodium | dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),Deoxythymidine-5'-triphosphate (dTTP) trisodium salt | DNA/RNA Synthesis |
Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate (dTTP) trisodium salt) is one of the four natural deoxynucleotides. It is used for the biosynthesis of deoxyribonucleic acid by DNA polymerase and ... | |||
T1508 | Decitabine | Dacogen,NSC 127716,Deoxycytidine,5-Aza-2'-deoxycytidine | Apoptosis , Nucleoside Antimetabolite/Analog , DNA Methyltransferase |
Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis... | |||
T1188 | Mizoribine | Bredinin,NSC 289637,HE 69 | HCV Protease , SARS-CoV , Tyrosinase |
Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis. | |||
T2218 | 8-Azaguanine | Azaguanine-8,SK 1150,NSC-749,SF-337 | Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite |
8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity. | |||
T1339 | 5-Azacytidine | Azacitidine,NSC 102816,Mylosar,Ladakamycin,5-AzaC | Nucleoside Antimetabolite/Analog , DNA Methyltransferase , Antibacterial , Antibiotic , Autophagy |
5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity. 5-Azacytidine regulates gene expression by decreasing the level of DNA methylation. 5-Azacytidine induces autopha... | |||
T3271 | Orotic acid zinc | Orotic acid zinc salt dihydrate,Zinc Orotate | Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite |
Orotic acid zinc (Zinc Orotate) salt dihydrate is an intermediate product in pyrimidine synthesis. | |||
T1272 | Cytarabine | Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , HSV |
Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity. | |||
T1506 | Vidarabine | Adenine Arabinoside,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A | Nucleoside Antimetabolite/Analog , Tyrosine Kinases , DNA/RNA Synthesis , Antibiotic , HSV |
Vidarabine (Adenine Arabinoside) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and signific... | |||
T8227 | 5'-Methylthioadenosine | Methylthioadenosine,5'-(Methylthio)-5'-deoxyadenosine,5'-Deoxy-5'-(methylthio)adenosine,5'-S-Methyl-5'-thioadenosine | Endogenous Metabolite |
5'-Methylthioadenosine (Methylthioadenosine) is produced from S-adenosylmethionine and behaves as a powful inhibitory product. | |||
T13791 | N2-methylguanine | DNA/RNA Synthesis , Endogenous Metabolite , Antibacterial | |
N2-methylguanine (N2-methylguanine) is an endogenous methylated nucleoside found in human fluids and a modified nucleoside. | |||
T4456 | N4-Acetylcytidine | N-Acetylcytidine | Others , Endogenous Metabolite |
N4-Acetylcytidine (N-Acetylcytidine) is a modified nucleoside. N4-acetylcytidine is an endogenous urinary nucleoside product of the degradation of transfer ribonucleic acid (tRNA); urinary nucleosides are biological mark... | |||
TNU0157 | 3’-O-Methyl guanosine | Endogenous Metabolite | |
Nucleoside Derivatives –3’-Modified nucleoside | |||
T20041 | 2'-Deoxyadenosine | NSC-141848,NSC141848,NSC 141848 | Endogenous Metabolite |
2'-Deoxyadenosine (NSC-141848) is the DNA nucleoside A. It pairs with deoxythymidine (T) in double-stranded DNA. | |||
T38251 | L-Uridine | Nucleoside Antimetabolite/Analog , Antibiotic | |
L-Uridine is the enantiomer of D-uridine, a nucleoside that acts as a phosphate acceptor for nucleoside phosphotransferase, in the normal RNA component of a normal RNA isolated from Polyporaceae fungus Poria cocos (Schw.... | |||
T13499 | 3-Methyluridine | Endogenous Metabolite | |
3-Methyluridine is a modified nucleoside of cellular RNA. | |||
T4972 | 2'-Deoxycytidine-5'-diphosphate trisodium | dCDP | Endogenous Metabolite |
2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) for the production of dCTP to support DNA biosynthesis and reverse transcription. | |||
T1709 | 2'-Deoxyinosine | Guanine deoxyriboside,Deoxyinosine | Others , Endogenous Metabolite |
2'-Deoxyinosine (Guanine deoxyriboside) inhibits the growth of human colon-carcinoma cell lines and is associated with purine nucleoside phosphorylase (PNP) deficiency. | |||
TMO2681 | Xanthosine | 9-Beta-D-Ribofuranosylxanthine,Xanthine riboside | Others , Endogenous Metabolite |
Xanthosine (9-Beta-D-Ribofuranosylxanthine) is a xanthine nucleoside that increases the number of mammary stem cells and milk production in goats and cattle. | |||
T2752 | 2'-Deoxyadenosine monohydrate | Others , Endogenous Metabolite | |
Deoxyadenosine, a deoxyribonucleoside, is a derivative of the nucleoside adenosine, differing from the latter by the replacement of a hydroxyl group (-OH) by hydrogen (-H) at the 2' position of its ribose sugar moiety. | |||
T7961 | N4-Benzoyl-2′-deoxycytidine | Others | |
N4-Benzoyl-2′-deoxycytidine is a synthetic nucleoside analog of the natural nucleoside deoxycytidine (dC), a competitive inhibitor of DNA polymerase. In vitro studies have shown that it inhibits replication in viruses, b... | |||
T4715 | 2'-Deoxyguanosine monohydrate | Guanine-2'-deoxyriboside | Others , Endogenous Metabolite |
2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) is a nucleoside consisting of the base guanine and the sugar deoxyribose. It is like guanosine, but with one oxygen atom removed. It is a nucleoside component of D... | |||
T22218 | 2'-Deoxyguanosine | Deoxyguanosine,Guanine deoxyriboside | Endogenous Metabolite |
2'-Deoxyguanosine (Guanine deoxyriboside) is a purine nucleoside that is recognized by members of the 2'-dG-II family.2'-Deoxyguanosine has been associated with aging, mutation, and carcinogenesis, and is oxidized by mol... | |||
T7457 | 5-Methyl-2'-deoxycytidine | 5-Methyldeoxycytidine,5MedCyd | DNA Methyltransferase , Endogenous Metabolite |
5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo. | |||
T7548 | 1-Methylguanosine | N1-Methylguanosine | Endogenous Metabolite |
1-Methylguanosine (N1-Methylguanosine) is a methylated nucleoside. It is known that some modified, especially methylated, nucleosides originating from RNA degradation are excreted in abnormal levels in the urine of patie... | |||
T6523 | Guanosine | DL-Guanosine,Vernine,Guanozin | Endogenous Metabolite , HSV |
Guanosine (DL-Guanosine) is a purine nucleoside formed from a beta-N9-glycosidic bond between guanine and a ribose ring and is essential for metabolism. | |||
TQ0193 | N2,N2-Dimethylguanosine | Endogenous Metabolite | |
N2,N2-Dimethylguanosine is an urinary nucleoside. The mean levels of urinary N2,N2-Dimethylguanosine in patients with colorectal cancer are significantly higher than those in patients with intestinal villous adenoma or h... | |||
T2993 | Cordycepin | 3'-Deoxyadenosine | MMP , TNF , Antibacterial , Antibiotic , Autophagy |
Cordycepin (3'-Deoxyadenosine) is a purine nucleoside antimetabolite and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplastic activity. | |||
T7004 | Tubercidin | Sparsomycin A,7-Deazaadenosine | Influenza Virus , DNA/RNA Synthesis , Antibacterial , Antibiotic |
Tubercidin (Sparsomycin A), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhib... | |||
T2812 | ATP disodium salt hydrate | ATP disodium,ATP disodium salt,Adenosine disodium triphosphate | Others , Endogenous Metabolite |
ATP disodium salt hydrate (Adenosine disodium triphosphate) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer. | |||
T13539 | Allopurinol riboside | Others , Endogenous Metabolite , Parasite , Drug Metabolite | |
Allopurinol riboside is a metabolite of allopurinol and shows effective activities against parasites. | |||
T64911 | Blasticidin S HCl | Antibiotic | |
Blasticidin S HCl is a peptide-based nucleoside antibiotic (antibiotic) isolated from Streptomyces griseochromogenes that inhibits prokaryotic and eukaryotic protein synthesis by interfering with the formation of peptide... | |||
TNU0052 | Nebularine | 9-(beta-D-Ribofuranosyl)-9H-purine | Apoptosis |
Nebularine (9-(beta-D-Ribofuranosyl)-9H-purine) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting inert lymphoid malignancies and inducing apoptosis.The anticancer mechanism of Nebulari... | |||
T5282 | 5-Methyluridine | Ribothymidine,Thymine riboside | Others , Endogenous Metabolite |
5-Methyluridine (Thymine riboside) is an endogenous methylated nucleoside found in human fluids; methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls.DNA hypermethy... | |||
T4897 | Inosine-5'-triphosphate trisodium salt | ITP,Inosine 5'-triphosphate trisodium salt | Others , Endogenous Metabolite |
Inosine-5'-triphosphate trisodium salt (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. Inosine-5'-triphosphate trisodium salt (ITP) may be used as a substra... | |||
T5288 | Cytidine-5'-triphosphate disodium | CTP,Cytidine 5'-triphosphate (disodium salt) | Others , Endogenous Metabolite |
Cytidine-5'-triphosphate disodium (CTP) is a pyrimidine nucleoside triphosphate that is involved in a variety of biochemical reactions. Cytidine-5'-triphosphate disodium is used in the synthesis of RNA by RNA polymerases... | |||
T6220 | Nicotinamide riboside chloride | Sirtuin , Endogenous Metabolite | |
Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+. | |||
T6599 | N6-methyladenosine | N-Methyladenosine,6-Methyladenosine,NSC-29409,m6A | Others , Influenza Virus , Endogenous Metabolite |
N6-methyladenosine (NSC-29409) is a methylated adenine residue. N6-Methyladenosine is an endogenous urinary nucleoside product of the degradation of transfer ribonucleic acid (tRNA); urinary nucleosides are biological ma... | |||
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カタログ番号 | 製品名 | Species | Expression System |
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TMPY-02279 | Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His) | Human | E. coli |
Purine nucleoside phosphorylase (PNP) is a purine-metabolizing enzyme that catalyzes the reversible phosphorolysis of 6-oxypurine (deoxy)nucleosides to their respective bases and (deoxy)ribose-1-phosphate. It is a key en... | |||
TMPJ-01308 | ITPase Protein, Human, Recombinant (His) | Human | E. coli |
Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphat... | |||
TMPY-00116 | MTH1 Protein, Human, Recombinant (His) | Human | E. coli |
NUDT1 (Nudix Hydrolase 1) is a Protein Coding gene. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates to monophosphates, thereby preventing misincorporation. The NUDT1... | |||
TMPY-02278 | NUDT2 Protein, Human, Recombinant (His) | Human | E. coli |
NUDT2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.3 kDa and the accession number is P50583. | |||
TMPY-03849 | NUDT5 Protein, Human, Recombinant (His) | Human | E. coli |
NUDT5 (Nudix Hydrolase 5) is a Protein Coding gene. This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphos... | |||
TMPY-04467 | NME1 Protein, Human, Recombinant (His) | Human | E. coli |
NME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the inter... | |||
TMPH-01631 | DCP2 Protein, Human, Recombinant (His) | Human | E. coli |
DCP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 48.4 kDa and the accession number is Q8IU60. | |||
TMPH-03284 | CD39 Protein, Rat, Recombinant (E. coli, His) | Rat | E. coli |
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP.... | |||
TMPH-03283 | CD39 Protein, Rat, Recombinant (His) | Rat | Baculovirus Insect Cells |
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP.... | |||
TMPY-02929 | ENTPD2 Protein, Human, Recombinant (aa 29-460, His) | Human | Baculovirus Insect Cells |
NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; ... | |||
TMPH-02964 | UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. A... | |||
TMPH-00156 | Ribonuclease Protein, Bacillus amyloliquefaciens, Recombinant (His) | Bacillus amyloliquefaciens | E. coli |
Hydrolyzes phosphodiester bonds in RNA, poly- and oligoribonucleotides resulting in 3'-nucleoside monophosphates via 2',3'-cyclophosphate intermediates. Ribonuclease Protein, Bacillus amyloliquefaciens, Recombinant (His)... | |||
TMPK-00853 | ENPP1 Protein, Human, Recombinant (N-His) | Human | HEK293 Cells |
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP... | |||
TMPK-00852 | ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP... | |||
TMPK-00781 | ENPP1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP... | |||
TMPH-01211 | DGUOK Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis de... | |||
TMPK-00854 | ENPP1 Protein, Human, Recombinant (C-His) | Human | HEK293 Cells |
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (eP... | |||
TMPH-03452 | NDPK Protein, S. cerevisiae, Recombinant (His) | Saccharomyces cerevisiae | P. pastoris (Yeast) |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Require... | |||
TMPH-03451 | NDPK Protein, S. cerevisiae, Recombinant (E. coli, His) | Saccharomyces cerevisiae | E. coli |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Require... | |||
TMPH-00099 | NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) | Arabidopsis thaliana | P. pastoris (Yeast) |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Plays a... | |||
TMPY-03617 | GMPR Protein, Human, Recombinant (His) | Human | E. coli |
GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family.This familyofenzymesincludesIMP dehydrogenaseandGMP reductase. These enzymes are involved inpurine metabolism and adopt aTIM barrelstructure. GMPR is an enzyme ... | |||
TMPJ-01406 | MOB4 Protein, Human, Recombinant (His) | Human | E. coli |
MOB-Like Protein Phocein is a member of the MOB1/Phocein Family. MOB-Like Protein Phocein is associated with membranes and the Golgi stacks. It is present in the cytosol, where it behaves as a protein complex. It has bee... | |||
TMPY-04480 | UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), re... | |||
TMPJ-00922 | DCK Protein, Human, Recombinant (His & T7) | Human | E. coli |
Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanos... | |||
TMPJ-00496 | PGM2 Protein, Human, Recombinant (His) | Human | E. coli |
Phosphoglucomutase-2 (PGM2) is a member of PGM family, which catalyzes the inter-conversion of sugar phosphates and participates in anabolic and catabolic reactions. When cells are grown in glucose, PGM catalyzes the con... | |||
TMPY-03508 | XTP3TPA Protein, Human, Recombinant (His) | Human | E. coli |
DCTPP1 hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. It has a strong preference for modified dCTP. DCTPP1’s activity is highest with 5-iodo-dCTP, followed by 5-bromo-d... | |||
TMPY-03330 | BPHL Protein, Human, Recombinant (His) | Human | E. coli |
BPHL is a member of the serine protease family. BPHL is expressed large quantities in liver and kidney and in minor quantities in heart, intestine and skeletal muscle. BPHL is a specific alpha-amino acid ester hydrola... | |||
TMPJ-00682 | CD39L1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CD39L1 protein (ENTPD2 or NTPDase2) is a member of the ecto-nucleoside triphosphate diphosphohydrolase family which the main role is termination of purinergic signaling. CD39L1 gene encodes a precursor protein with 495 a... | |||
TMPY-02893 | NT5C3A/NT5C3 Protein, Human, Recombinant | Human | E. coli |
NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded prot... |
カタログ番号 | 製品名 | ||
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L1720 | Nucleotide Compound Library | 334 compounds | |
A unique collection of 334 nucleoside and nucleotide analogues, can be used for research and development of anti-viral, anti-tumor, anti-fungal, and anti-depressive drugs; |