|
T4246 |
Varenicline dihydrochloride
|
|
AChR
|
|
Varenicline dihydrochloride is a Selective α4β2 nicotinic acetylcholine receptor partial agonist. |
|
T12855 |
SB 258719
|
|
5-HT Receptor
|
|
|
|
T3565 |
VU0155041
|
UV0155041,VU-0155041 |
GluR
|
|
VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat). |
|
T22016 |
A-582941 dihydrochloride
|
A 582941 |
5-HT Receptor
,
AChR
|
|
A-582941 dihydrochloride (A 582941) is a Selective agonist of α7 nAChR partial |
|
T7806 |
Licarbazepine
|
10,11-hydroxy-10,11 Dihydrocarbamezer |
Others
|
|
Licarbazepine (10,11-hydroxy-10,11 Dihydrocarbamezer) is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders. |
|
T23264 |
RS 56812 hydrochloride
|
|
Others
|
|
5-HT3 partial agonist |
|
T28303 |
Pazinaclone
|
A-77000,DN-2327,DN2327,DN 2327,A 77000,A77000 |
GABA Receptor
|
|
Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity. |
|
T3285L |
Eslicarbazepine
|
Pazzul,EC 810-248-9,BIA 2-194,Stedesa,Erelib |
Beta-Secretase
,
Sodium Channel
|
|
Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures. |
|
T72027 |
6-Methyl-3-pyridinecarboxaldehyde
|
6-Methoxynicotinaldehyde |
|
|
6-Methyl-3-pyridinecarboxaldehyde (6-Methoxynicotinaldehyde) has partial antitumor activity. |
|
T28197 |
NS-2710
|
NS 2710,NS2710 |
GABA Receptor
|
|
NS-2710 is a non-selective GABA(A) receptor partial agonist for the study of anxiety disorders. |
|
T22671 |
CJ 033466
|
|
5-HT Receptor
|
|
CJ 033466 is a selective partial agonist of 5-HT4 receptor (EC50 = 9 nM) with gastroprokinetic effect. |
|
TP2048L |
α-helical CRF 9-41 acetate
|
α-helical CRF 9-41 acetate(90880-23-2 Free base) |
CRFR
|
|
α-helical CRF 9-41 acetate is a competitive antagonist of CRF2 (KB = 100 nM) and a partial agonist of CRF1 (EC50 = 140 nM). |
|
T22817 |
GSK 789472 hydrochloride
|
GSK-789472 HCl,1-phenyl-3-(piperidin-2-ylmethyl)imidazolidin-2-one hydrochloride,4,5-Dihydro-1-phenyl-3-(2-piperidinyl)methylimidazol-2(1H)-one |
Dopamine Receptor
|
|
GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist. |
|
T27845 |
Losigamone
|
ADD-137022,AO33,AO 33,ADD 137022,AO-33,ADD137022;Losigamone |
GABA Receptor
|
|
Losigamone (AO-33) is an agonist of GABA receptor and can be used in studies about the treatment of partial seizures. |
|
T3431 |
Pardoprunox hydrochloride
|
SLV-308 hydrochloride,DU-126891 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
|
|
Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A recept... |
|
T0818 |
Decamethonium bromide
|
Decacuran,Syncurine |
AChR
,
AChE
|
|
Decamethonium bromide (Syncurine) is a neuromuscular blocker and nicotinic AChR partial agonist. |
|
T23168 |
PNU 22394 hydrochloride
|
|
5-HT Receptor
|
|
PNU 22394 hydrochloride is a 5-HT2C agonist and partial 5-HT2A/5-HT2B agonist |
|
T68065 |
Enloplatin
|
|
|
|
Enloplatin is a carboplatin analog that has a partial role in advanced ovarian cancer. |
|
T13424 |
(1R,2S)-VU0155041
|
|
GluR
|
|
(1R,2S)-VU0155041 is the cis regioisomer of VU0155041 and a partial agonist of mGluR4. |
|
T28856 |
SSR180711 hydrochloride
|
SSR-180711A HCl,SSR-180711C HCl,SR-180711 HCl |
AChR
|
|
SSR180711 hydrochloride (SSR-180711A HCl) is a selective Alpha7 nicotinic acetylcholine partial agonist for the study of neurodegenerative and cognitive disorders. |
|
T22348 |
Isonipecotic acid
|
4-Piperidinecarboxylic acid,Hexahydroisonicotinic acid,4-Carboxypiperidine |
GABA Receptor
|
|
Isonipecotic acid (4-Piperidinecarboxylic acid) is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist. |
|
T37527L |
[Orn8]-Urotensin II acetate
|
|
GPR
|
|
[Orn8]-Urotensin II acetate is a Urotensin receptor ligand and a partial agonist at Urotensin receptors. |
|
T68154 |
TC-2216
|
|
AChR
|
|
TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression. |
|
T3970 |
BMS-779788
|
XL652,EXEL04286652,XL 652,XL-652,BMS-788 |
Liver X Receptor
|
|
BMS-779788 (XL-652) is an LXRα/β partial agonist (IC50: 68/14 nM). |
|
T12761 |
Ro 10-5824 dihydrochloride
|
|
Dopamine Receptor
|
|
Ro 10-5824 dihydrochloride is a selective agonist of dopamine D4 receptor partial, (Ki of 5.2 nM). |
|
T7412 |
Tandospirone citrate
|
SM-3997 citrate |
5-HT Receptor
|
|
Tandospirone citrate (SM-3997 citrate) is a potent and selective 5-HT1A receptor partial agonist (Ki : 27 nM) |
|
T21955 |
GQ-16
|
|
PPAR
|
|
GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain. |
|
T2285 |
Encenicline hydrochloride
|
EVP-6124 (hydrochloride),EVP-6124 hydrochloride |
AChR
|
|
Encenicline hydrochloride (EVP-6124 hydrochloride) is a new-type partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). |
|
T21468 |
CVT-2738
|
UNII-NYS3I6283H,CVT 2738,EC 610-916-8,CVT2738,RS-94287 |
Others
|
|
CVT-2738 (RS-94287) is a metabolite of Ranolazine. Ranolazine is a partial fatty acid oxidation (pFOX) inhibitor and anti-anginal drug. |
|
T8959 |
OS-3-106
|
|
Dopamine Receptor
|
|
OS-3-106 is a novel arylamide phenylpiperazines, as partial agonists at the D3R in the adenylyl cyclase inhibition assay. |
|
T1860 |
Imepitoin
|
AWD 131-138,ELB-138 |
GABA Receptor
|
|
Imepitoin (AWD 131-138) is a new low-affinity partial benzodiazepine receptor agonist. It shows potent anticonvulsant and anxiolytic properties in rodent models. |
|
T24579 |
Oxyfedrine L-form HCl
|
Modacor,Oxyfedrine L-form hydrochloride,D563,Ildamen,D 563,D-563 |
Adrenergic Receptor
|
|
Oxyfedrine L-form HCl (Ildamen) is a partial agonist at beta-adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent. |
|
T16844 |
Sarmazenil
|
R-154513,Ro 15-3505 |
GABA Receptor
|
|
Sarmazenil (Ro 15-3505) is a partial inverse agonist at the benzodiazepine receptor with pro-convulsant properties and is used in the study of chronic hepatic encephalopathy (HE). |
|
T9081 |
FAUC 346
|
|
Dopamine Receptor
|
|
FAUC 346 is a highly selective D3 partial agonist with EC50 of 1.5 nM. |
|
T22542 |
1-Aminocyclobutanecarboxylic acid
|
ACBC |
NMDAR
,
iGluR
|
|
1-Aminocyclobutanecarboxylic acid (ACBC) is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1]. |
|
T28435 |
PNU-96391
|
PNU 96391,OSU6162,PNU96391,OSU 6162,OSU-6162 |
Dopamine Receptor
,
5-HT Receptor
|
|
PNU-96391 (OSU-6162) is an antagonist of dopamine D2 and a partial agonist of 5-HT2A. PNU-96391 can be used in research on the treatment of chronic diseases. |
|
T5819 |
Rapastinel Trifluoroacetate
|
Thr-Pro-Pro-Thr-NH2 Trifluoroacetate,GLYX-13 Trifluoroacetate |
NMDAR
,
iGluR
|
|
Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) is an NMDA receptor modulator with glycine-site partial agonist properties. |
|
T3407L |
Rapastinel acetate
|
Rapastinel acetate (117928-94-6 Free base) |
NMDAR
,
iGluR
|
|
Rapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects. |
|
T22871 |
Ipsapirone
|
|
5-HT Receptor
|
|
Ipsapirone is a partial agonist of 5-HT1A receptor and produces an inhibitory effect on 5-HT2 and the α1-adrenergic function at high doses. |
|
T16022 |
Arhalofenate
|
JNJ 39659100,MBX 102 |
PPAR
|
|
Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes. |
|
T68114L |
Nardeterol HCl
|
Nardeterol HCl(73865-18-6 Free base) |
Adrenergic Receptor
|
|
Nardeterol HCl is a β-adrenergic receptor partial agonist used in the study of the central nervous system.CAS 번호13460-73-83-4 |
|
T27439 |
GS-9667
|
CVT-3619,CVT 3619 |
Adenosine Receptor
|
|
GS-9667, a selective and partial agonist of the A(1) adenosine receptor (AR), represents an effective therapy for Type 2 diabetes (T2DM) and dyslipidemia via lowering of free fatty acids (FFA). |
|
T23631 |
Adatanserin
|
WY-50324,WY 50324,WAY SEB 324,WY50324 |
5-HT Receptor
|
|
Adatanserin (WY 50324) is a mixed 5-HT1A receptor partial agonist and a 5-HT2A and 5-HT2C receptor antagonist with potential neuroprotective activity for the study of anxiety and depression. |
|
T22818 |
GSK9027
|
GR agonist 23a,GSK 9027,GSK-9027 |
Glucocorticoid Receptor
|
|
GSK9027 (GR agonist 23a) is a nonsteroidal glucocorticoid receptor (GR) agonist.GSK9027 is a partial agonist on the 2×GRE reporter gene compared to dexamethasone and is less active than dexamethasone activity. |
|
T68000L |
MK-0533
|
|
PPAR
|
|
MK-0533 is a novel PPARγ partial agonist for the prevention of vascular endothelial dysfunction (VED) and VED-related cardiovascular disease. |
|
T23286 |
S 24795
|
Catestatin acetate(142211-96-9 free base),LNAChR |
AChR
|
|
S 24795 (Catestatin acetate(142211-96-9 free base)) is an α7 nAChR partial agonist. S 24795 improves mnemonic function in aged mice and can be used in studies about aging-related memory disturbances. |
|
T8600 |
N-ACETYLTRYPTAMINE
|
|
Melatonin Receptor
|
|
N-ACETYLTRYPTAMINE is a partial agonist for melatonin receptors in the retina. Also used for determination of serotonin N-acetyl transferase. |
|
T3992 |
MSX-122
|
MSX 122,MSX122 |
CXCR
|
|
MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM). |
|
T12156 |
N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea
|
|
Others
|
|
N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea is an anticonvulsant agent, treatment of generalized tonic-clonic and partial seizures. |
|
TP1941L1 |
Ac-RYYRWK-NH2 acetate
|
|
Opioid Receptor
|
|
Ac-RYYRWK-NH2 acetate is a potent partial agonist of the nociceptin receptor(NOP), which is the endogenous ORL1 receptor agonist. |
