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Search Results for " GABA "

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カタログ番号 製品名 別名 ターゲット
T40659L γ-Acetylenic GABA hydrochloride γ-Acetylenic GABA hydrochloride(57659-38-8 Free base) Transaminase , GABA Receptor
γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor.
T17649 Boc-GABA-OH Others , PROTAC Linker
Boc-GABA-OH serves as a PROTAC linker essential for synthesizing UNC6852, an EED-targeted PROTAC[1].
T40659 γ-Acetylenic GABA 4-Aminohex-5-ynoic acid,γ-Acetylenic GABA
γ-Acetylenic GABA (4-Aminohex-5-ynoic acid) is a potent, irreversible inhibitor of GABA-transaminase. This compound effectively raises the concentration of γ-Aminobutyric acid (GABA) in the brain of rats.
T21409 GABOB (beta-hydroxy-GABA) β-hydroxy-GABA,beta-hydroxy-GABA,GABOB
GABOB is an anticonvulsant used to treat epilepsy. GABOB is an endogenous active metabolite, it is analogue to the neurotransmitter γ-aminobutyric acid (GABA), therefore may function as a neurotransmitter.
T3290 Pikamilone Picamilon,Nicotinoyl-GABA Others
Pikamilone (Picamilon) is an intelligent medicine.
T23277 RuBi-GABA Others
Ruthenium-bipyridine-triphenylphosphine caged GABA
T23276 RuBi GABA trimethylphosphine Others
GABAB receptor agonist
T22509 3-Methyl-GABA Others
3-Methyl-GABA, an anticonvulsant agent [1] [2], acts as a potent activator of GABA aminotransferase, fits the binding pocket of the GABA A receptor (GABAaR), and activates L-glutamic acid decarboxylase (GAD).
T0028 Gamibetal 3-Hydroxy-GABA,4-Amino-3-hydroxybutyric Acid HIV Protease
Gamibetal (4-Amino-3-hydroxybutyric Acid) is used as a chiral reagent in the synthesis of antiepileptic and hypotensive drug GABOB and analogues. Also used in the preparation of HIV-1 inhibitors derived from Betulinic Ac...
T22364 Methyl 4-aminobutyrate HCl Methyl 4-aminobutyrate hydrochloride,GABA methyl ester Others
Methyl 4-aminobutyrate HCl (GABA methyl ester) is a methyl ester compound derived from the condensation of aminobutyric acid and methanol.
T82356 GABA-IN-1
GABA-IN-1 (Compound 6), a GABA inhibitor, exhibits larvicidal and insecticidal properties, achieving a mortality rate of 93% at a concentration of 50 mg/L [1].
T82355 GABA-IN-2
GABA-IN-2 (Compound 5), a GABA inhibitor, exhibits both larvicidal and insecticidal properties, achieving an 87% mortality rate at a concentration of 50 mg/L [1].
T62185 GABA-AT-IN-1
GABA-AT-IN-1 (Compound 6) is an inhibitor of γ-aminobutyric acid transaminase (GABA-AT) that crosses the blood-brain barrier.
T82357 GABA receptor Antagonist 1 GABA Receptor
GABA receptor Antagonist 1 (compound 7w) effectively inhibits the Px RDL1 GABAR at an IC50 of 7.08 nmol/L and demonstrates insecticidal efficacy against P. xylostella, S. frugiperda, S. exigua, and S. litura with respect...
T3290L Pikamilone Sodium GABA-NG,Nicotinoyl-GABA sodium salt,GABA NG,GABANG,Pikamilone Na
Pikamilone Sodium is a prodrug of GABA used for therapy of neurogenic bladder in spinal and benign prostatic hyperplasia.
T0128L Vigabatrin Hydrochloride γ-Vinyl-GABA hydrochloride GABA Receptor
Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA), which irreversibly inhibits the catabolism of GABA by GABA transaminase.
T4176 Rac-BHFF (R,S)-BHFF GABA Receptor
rac-BHFF ((R,S)-BHFF) is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectively). It exhibits anxiolytic activity in vivo an...
T1065 Baclofen Lioresal GABA Receptor
Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist sp...
T14571 Bifenazate GABA Receptor
Bifenazate is a carbazate acaricide that control 100% of mites at a concentration of 25 ppm[1] and it also is a positive allosteric modulator of GABA receptor[2].
T4440 Saclofen GABA Receptor
Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7.8 μM).1 This compound can be used to determine the function...
T10618 Broflanilide GABA Receptor
Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL GABAR (IC50: 1.3 nM).
TQ0023 Lorediplon GABA Receptor
Lorediplon is a novel hypnotic drug acting as a GABAA receptor modulator, differentially active at the α1-subunit, associated with promoting sleep.
T7794 Zuranolone GABA Receptor
Zuranolone is an agonist of GABAA receptor.
T15775 Lotilaner GABA Receptor , Parasite
Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA receptor). It also has no effect on a dog GABAA receptor.
T26834 BL-1020 Mesylate CYP-1020 Mesylate Dopamine Receptor , GABA Receptor
BL-1020 Mesylate (CYP-1020 Mesylate) is an orally available GABA A receptor agonist and D2 antagonist that decreases dopamine activity and enhances GABAA activity.BL-1020 Mesylate has been used in the study of schizophre...
T16539 Piperazine citrate GABA Receptor
Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring. It used as an Anthelmintic.
T5375 Loreclezole GABA Receptor
Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit-containing receptors.
T8630 Baclofen hydrochloride 4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride GABA Receptor
Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, espe...
T26600 Alpidem Ananxyl GABA Receptor
Alpidem (Ananxyl) is an anxiolytic drug from the imidazopyridine family. Alpidem does not produce sedative effects at normal doses, and is instead used specifically for the treatment of anxiety. Alpidem has nanomolar bin...
T11822 LAU159 GABA Receptor
LAU159 is a functionally selective positive α1β3 GABA(A) receptor modulator(EC50 : 2.2 μM).
T9424 Temgicoluril Tetramethylglycoluril,mebikar GABA Receptor
Temgicoluril (mebikar) acts on GABA Receptor.
T7136 AZD-6280 GABA Receptor
AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.
T3644 U93631 GABA Receptor
GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. Accelerates the decay of GABA-induced Cl- currents with little effect on peak amplitude...
T8572 CL 218872 GABA Receptor
CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α1, α2, α3, α4, α5 and α6-subunit containing receptor...
T17144 TPA 023 GABA Receptor
TPA 023 is an agonist of the GABAA α2/α3 subtype-selective (Ki: 0.19-0.41 nM).
T7622 Gabazine SR95531 GABA Receptor
Gabazine (SR95531) is an antagonist of GABAA receptors (Ki : 74-150 nM)
T0715 Chlormezanone Trancopal Others , GABA Receptor
Chlormezanone (Trancopal) is a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
T3173 DAA-1106 DAA1106 Others , GABA Receptor
DAA-1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR), acting as a potent and selective agonist at the peripheral benzodiazepine receptor.
T36520 COR659 Cannabinoid Receptor , GABA Receptor
COR659 is a GABAB positive allosteric modulator (PAM) . COR659 suppresses alcohol and chocolate self-administration in rats[1]. COR659 apparently exerts its effects via a composite mechanism, including positive allosteri...
T1240 Flumazenil Ro 15-1788 GABA Receptor
Flumazenil (Ro 15-1788) antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous system (CNS), thereby preventing the chloride channel openi...
T2196 Fipronil Fluocyanobenpyrazole,Termidor P450 , GluCls , GABA Receptor
Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gat...
T13536 Afoxolaner Chloride channel , GABA Receptor , Parasite
Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting i...
T11349 GABAA receptor agent 1 GABA Receptor
GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor.
T1128 Oxiracetam ISF2522 GABA Receptor
Oxiracetam (ISF2522), a cyclic derivative of gamma-aminobutyric acid (GABA), is utilized for the treatment of cognitive impairments.
T8887 2'MeO6MF GABA Receptor
2'MeO6MF is a brain-penetrant positive allosteric modulator at α2β1γ2L and all α1-containing GABAA receptors.It offers neuroprotection and improved functional recovery and dampens the stroke-induced inflammatory response...
T23104 Ocinaplon DOV 273547 GABA Receptor
Ocinaplon (DOV 273547) is a GABAA receptors modulator.
TQ0040 ONO-8590580 CS-2894 GABA Receptor
ONO-8590580 (CS-2894) is a negative allosteric modulator of GABAA α5.
T21793 CGP 35348 GABA Receptor
CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after neonatal brain damage in albino mice.
T11684 Isoguvacine hydrochloride 1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride GABA Receptor
Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) is a GABA receptor agonist. Isoguvacine hydrochloride binds to rat synaptic cortical membranes and activates α1β2γ2S, α2β2γ2S, α3β2γ2...
T2067 NS11394 NS 11394 GABA Receptor
NS11394 is a effective and subtype-selective GABA(A) receptor-positive modulator; possesses a functional efficacy selectivity profile of α(5) > α(3) > α(2) > α(1) at GABA(A) alpha subunit-containing receptors.

Compounds

γ-Acetylenic GABA hydrochloride
T40659L
Synonym: γ-Acetylenic GABA hydrochloride(57659-38-8 Free base)
Target: Transaminase, GABA Receptor
Boc-GABA-OH
T17649
Synonym:
Target: Others, PROTAC Linker
γ-Acetylenic GABA
T40659
Synonym: 4-Aminohex-5-ynoic acid,γ-Acetylenic GABA
Target:
GABOB (beta-hydroxy-GABA)
T21409
Synonym: β-hydroxy-GABA,beta-hydroxy-GABA,GABOB
Target:
Pikamilone
T3290
Synonym: Picamilon,Nicotinoyl-GABA
Target: Others
RuBi-GABA
T23277
Synonym:
Target: Others
RuBi GABA trimethylphosphine
T23276
Synonym:
Target: Others
3-Methyl-GABA
T22509
Synonym:
Target: Others
Gamibetal
T0028
Synonym: 3-Hydroxy-GABA,4-Amino-3-hydroxybutyric Acid
Target: HIV Protease
Methyl 4-aminobutyrate HCl
T22364
Synonym: Methyl 4-aminobutyrate hydrochloride,GABA methyl ester
Target: Others
GABA-IN-1
T82356
Synonym:
Target:
GABA-IN-2
T82355
Synonym:
Target:
GABA-AT-IN-1
T62185
Synonym:
Target:
GABA receptor Antagonist 1
T82357
Synonym:
Target: GABA Receptor
Pikamilone Sodium
T3290L
Synonym: GABA-NG,Nicotinoyl-GABA sodium salt,GABA NG,GABANG,Pikamilone Na
Target:
Vigabatrin Hydrochloride
T0128L
Synonym: γ-Vinyl-GABA hydrochloride
Target: GABA Receptor
rac-BHFF
T4176
Synonym: (R,S)-BHFF
Target: GABA Receptor
Baclofen
T1065
Synonym: Lioresal
Target: GABA Receptor
Bifenazate
T14571
Synonym:
Target: GABA Receptor
Saclofen
T4440
Synonym:
Target: GABA Receptor
Broflanilide
T10618
Synonym:
Target: GABA Receptor
Lorediplon
TQ0023
Synonym:
Target: GABA Receptor
Zuranolone
T7794
Synonym:
Target: GABA Receptor
Lotilaner
T15775
Synonym:
Target: GABA Receptor, Parasite
BL-1020 Mesylate
T26834
Synonym: CYP-1020 Mesylate
Target: Dopamine Receptor, GABA Receptor
Piperazine citrate
T16539
Synonym:
Target: GABA Receptor
Loreclezole
T5375
Synonym:
Target: GABA Receptor
Baclofen hydrochloride
T8630
Synonym: 4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride
Target: GABA Receptor
Alpidem
T26600
Synonym: Ananxyl
Target: GABA Receptor
LAU159
T11822
Synonym:
Target: GABA Receptor
Temgicoluril
T9424
Synonym: Tetramethylglycoluril,mebikar
Target: GABA Receptor
AZD-6280
T7136
Synonym:
Target: GABA Receptor
U93631
T3644
Synonym:
Target: GABA Receptor
CL 218872
T8572
Synonym:
Target: GABA Receptor
TPA 023
T17144
Synonym:
Target: GABA Receptor
Gabazine
T7622
Synonym: SR95531
Target: GABA Receptor
Chlormezanone
T0715
Synonym: Trancopal
Target: Others, GABA Receptor
DAA-1106
T3173
Synonym: DAA1106
Target: Others, GABA Receptor
COR659
T36520
Synonym:
Target: Cannabinoid Receptor, GABA Receptor
Flumazenil
T1240
Synonym: Ro 15-1788
Target: GABA Receptor
Fipronil
T2196
Synonym: Fluocyanobenpyrazole,Termidor
Target: P450, GluCls, GABA Receptor
Afoxolaner
T13536
Synonym:
Target: Chloride channel, GABA Receptor, Parasite
GABAA receptor agent 1
T11349
Synonym:
Target: GABA Receptor
Oxiracetam
T1128
Synonym: ISF2522
Target: GABA Receptor
2'MeO6MF
T8887
Synonym:
Target: GABA Receptor
Ocinaplon
T23104
Synonym: DOV 273547
Target: GABA Receptor
ONO-8590580
TQ0040
Synonym: CS-2894
Target: GABA Receptor
CGP 35348
T21793
Synonym:
Target: GABA Receptor
Isoguvacine hydrochloride
T11684
Synonym: 1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride
Target: GABA Receptor
NS11394
T2067
Synonym: NS 11394
Target: GABA Receptor
1 2 3 4 5
カタログ番号 製品名 別名 ターゲット
T4728 4-Acetamidobutanoic acid N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID GABA Receptor , Endogenous Metabolite , Antibacterial
4-Acetamidobutanoic acid (4-ACETAMIDOBUTYRIC ACID) can be found in blood, feces, and urine, as well as in human prostate tissue. 4-Acetamidobutanoic acid exists in all eukaryotes, ranging from yeast to humans. 4-Acetamid...
T0508 γ-Aminobutyric acid Gamma-aminobutyric acid,4-Aminobutyric acid,GABA,4-Aminobutanoic acid,Piperidic acid GABA Receptor , Endogenous Metabolite
γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.
TN1023 Miltirone P450 , GABA Receptor
Miltirone is a CYPs inhibitor, it has been characterized as a low-affinity ligand for central benzodiazepine receptors.
TQ0119 Cirsimaritin GABA Receptor
T5754 Kavain NF-κB , GABA Receptor
Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of transcriptional factors such as NF-kB and LITAF.
T7557 Guvacine hydrochloride GABA Receptor
Guvacine hydrochloride is an inhibits of GABA uptake (IC50 : 10 μM)
T3782 Jujuboside A transporter , GABA Receptor
Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, having neurophysiological inhibitory effects, used as a potential therapeutic agent for the treatment of Alzheimer s disease.
T8036 6-Methylflavone GABA Receptor
6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.
T3S2100 (-)-Securinine Securinine GABA Receptor
(-)-Securinine (Securinine) is plant-derived alkaloid and also a GABAA receptor antagonist.
T5799 Arecaidine hydrochloride Others
Arecaidine hydrochloride may have carcinogenesis.
TN1217 2'-O-Methylisoliquiritigenin Dopamine Receptor , 5-HT Receptor , GABA Receptor
2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a ...
T2979 DL-Menthol Hexahydrothymol,(±)-Menthol GABA Receptor , AChE
DL-Menthol ((±)-Menthol) is a racemic mixture of the monoterpene alcohols (–)-menthol and (+)-menthod, which have been found in Cannabis. (–)-Menthol is more common than (+)-menthol in nature and exhibits analgesic, anti...
T2749 Ginkgolide A BN-52020 GABA Receptor , Endogenous Metabolite
Ginkgolide A (BN-52020) is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders.
T8268 6,2'-Dihydroxyflavone GABA Receptor
6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.
T2850 Bicuculline (+)-Bicuculline,d-Bicuculline GABA Receptor
Bicuculline ((+)-Bicuculline) is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungos...
T1396 Bemegride Bemegrid,3-Ethyl-3-methylglutarimide,Agipnon GABA Receptor
Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.
T3698 Alpha-Asarone α-Asarone,trans-Asarone P450 , GABA Receptor , HMG-CoA Reductase
alpha-Asarone (trans-Asarone) is a psychoactive compound with antidepressant-like activity in mice.
T2720 Ginsenoside Rc Panaxoside Rc Others , TNF , GABA Receptor , Interleukin
Ginsenoside Rc (Panaxoside Rc) is one of the ginsenosides from Panax ginseng, inhibits the expression of TNF-α and IL-1β.
TMS0418 Dihydroergotoxine mesylate Ergoloid mesylates GABA Receptor
Dihydroergotoxine mesylate (Ergoloid mesylates) is mainly used to improve symptoms and physical symptoms of mental degeneration related to aging.
T5S1882 Songorine Napellonine,Zongorine,Bullatine G Others , GABA Receptor
Songorine (Napellonine) shows favorable anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.
TN1202 (-)-α-Pinene (1S)-(-)-Alpha-Pinene Virus Protease , GABA Receptor , Endogenous Metabolite , Antibacterial
(-)-α-Pinene ((1S)-(-)-Alpha-Pinene) enhances the quantity of NREMS without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission, acting as a partial modulator of GABAA-BZD receptors and directl...
T4590 (+)-Kavain Kavain,L-KAWAIN,(R)-KAWAIN Calcium Channel , GABA Receptor , Sodium Channel , Monoamine Transporter
(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
TN1325 (2S)-6-Prenylnaringenin 6-Prenylnaringenin,6-PN GABA Receptor
(2S)-6-Prenylnaringenin (6-Prenylnaringenin) is an isomer of the potent phytoestrogen, 8-prenylnaringenin. (2S)-6-Prenylnaringenin is the most potent compound in the forebrain and acts as a positive allosteric modulator ...
T7595 L-DABA L-2,4-Diaminobutyric acid,L-DAB HBR GABA Receptor , Endogenous Metabolite
L-DABA (L-2,4-Diaminobutyric acid) is an inhibitor of GABA transaminase (IC50 > 500 μM).
T8040 Cholesterol myristate Cholesteryl myristate,Cholesteryl tetradecanoate Others , Potassium Channel , GABA Receptor , Endogenous Metabolite , AChR
Cholesterol Myristate (Cholesteryl Myristate) is a natural steroid found in traditional Chinese medicine that interacts with various ion channels, including the GABAA receptor, nicotinic acetylcholine receptor, and the i...
T2983 3,4,5-Trimethoxycinnamic acid 3-(3,4,5-Trimethoxyphenyl)acrylic Acid,O-Methylsinapic acid GABA Receptor , Endogenous Metabolite
3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GABAA/BZ receptor complex.
T0710 L-Cycloserine Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,(S)-4-Amino-3-isoxazolidone HIV Protease , GABA Receptor
L-Cycloserine ((-)-Cycloserine) irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals, results in increased levels of gamma-aminobutyric acid (G...
T8193 α-Thujone Thujone,ALPHA-(-)-THUJONE Apoptosis , Reactive Oxygen Species , GABA Receptor , AChR , Parasite , Autophagy
α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
T2S1814 P-Hydroxybenzaldehyde 4-Formylphenol,4-hydroxybenzaldehyde,p-Oxybenzaldehyde Transaminase , GABA Receptor , Endogenous Metabolite
1. p-Hydroxybenzaldehyde (p-Oxybenzaldehyde) shows an inhibitory effect on the GABA transaminase to contribute to an antiepileptic and anticonvulsive activity, and its inhibitory activity was higher than that of valproic...
T2S1464 Thiocolchicoside Thiocolchicine 2-glucoside analog,Coltramyl Others , GABA Receptor
Thiocolchicoside (Thiocolchicine 2-glucoside analog) (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine rece...
T3417 Amentoflavone Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin Apoptosis , P450 , Phospholipase , Reactive Oxygen Species , Opioid Receptor , COX , Antibacterial , RSV , Antifungal
Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhib...
TJS0123 Guvacine ethyl ester PT00442-2 Others
Guvacine ethyl ester (Arecoline) is an alkaloid found in betel nut that is used in the synthesis of GABA uptake inhibitors.
TN2865 (E)-3,4,5-Trimethoxycinnamic acid O-Methylsinapic acid,3,4,5-Trimethoxy-trans-cinnamic acid,3,4,5-Trimethoxyphenylacrylic acid Others
(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural product from the roots and rhizomes of Notopterygium incisum.
T5734 (+)-BORNEOL d-Borneol GABA Receptor
(+)-BORNEOL (d-Borneol) is a natural bicyclic monoterpene used for analgesia and anesthesia in traditional Chinese medicine; enhances GABA receptor activity with an EC50 of 248 μM.
T3741 (-)-borneol L-Borneol GABA Receptor
(-)-borneol (L-Borneol) has a highly efficacious positive modulating action at GABA receptor with an EC50 of 237 μM.
TN3174 6-Methoxyflavanone NSC50184 GABA Receptor
6-Methoxyflavanone (6-MeOF) is A positive allosteric modulator of the GABA response of human recombinant GABA A receptor, with antianxiety and anti-inflammatory activity, and can be used to reduce cisplatin induced neuro...
T5776 Pimpinellin Apoptosis , Anti-infection
Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.
T0627 β-Alanine beta-Alanine,3-Aminopropanoic acid,2-Carboxyethylamine GABA Receptor , Endogenous Metabolite
β-Alanine (3-Aminopropanoic acid) is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotransmitter by activating glycine and GABA receptors.
T39359 γ-Glu-Gly gamma-Glutamylglycine Amino Acids and Derivatives
γ-Glu-Gly (gamma-Glutamylglycine), a γ-glutamyl dipeptide, is a human lipid metabolite with a structure resembling that of GABA (γ-aminobutyric acid). It functions as an antagonist of excitatory amino acids.
T0883 Tramiprosate Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed Beta Amyloid , GABA Receptor
Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble Aβ and maintains it in a non-protofibrillar form.It is a GAB...
TN1308 6-Hydroxyflavanone Others , Lipoxygenase , COX , GABA Receptor
6-Hydroxyflavanone, extracted from the leaves of Acorus calamus, exhibits anti-inflammatory and anti-neuropathic pain activity by targeting cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), as well as opioid and GABA-A r...
T4814 (R)-5-Oxopyrrolidine-2-carboxylic acid D-Pyroglutamic acid,(R)-(+)-2-Pyrrolidone-5-carboxylic acid Others , Endogenous Metabolite
(R)-5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) is a cyclic derivative of glutamic acid, physiologically present in mammalian tissues. It has been shown that PCA releases GABA from the cerebral cortex and di...
T3578 Pyridoxal phosphate PLP,PAL-P,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate Reverse Transcriptase , Endogenous Metabolite
Pyridoxal phosphate (Vitamin B6 phosphate) is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and d...
T4881 Phosphorylethanolamine O-Phosphorylethanolamine Others , Endogenous Metabolite
Phosphorylethanolamine (O-Phosphorylethanolamine) is a phosphomonoester metabolite of the phospholipid metabolism. Phosphorylethanolamine is a precursor of phospholipid synthesis and a product of phospholipid breakdown. ...
T5089 5-Aminovaleric acid Others , Endogenous Metabolite
5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine. 5-aminovalerate is formed via the following multi-step reaction:...
T3S2259 Methyl eugenol 4-allylveratrole,eugenyl methyl ether,O-methyleugenol,Eugenol Methyl ether GABA Receptor
1. Methyl eugenol (4-allylveratrole) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcinogenic potential of ME, the need to check its...
TN3702 (-)-Corlumine GABA Receptor
Corlumine exhibits spasmolytic and GABA antagonist activity.
TN1717 Guvacine GABA Receptor
Guvacine can enhance the inhibition of spinal neurones by GABA.
T80014 Guvacine hydrobromide GABA Receptor
Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake. It effectively inhibits rat GABA transporter isoforms GAT-1, GAT-2, and GAT-3, with respec...
TN4298 Isohyenanchin GABA Receptor
Isohyenanchin is the potent antagonist of RDLac homo-oligomers, it is also a weak antagonist of ionotropic GABA receptors.
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天然物製品

4-Acetamidobutanoic acid
T4728
Synonym: N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID
Target: GABA Receptor, Endogenous Metabolite, Antibacterial
γ-Aminobutyric acid
T0508
Synonym: Gamma-aminobutyric acid,4-Aminobutyric acid,GABA,4-Aminobutanoic acid,Piperidic acid
Target: GABA Receptor, Endogenous Metabolite
Miltirone
TN1023
Synonym:
Target: P450, GABA Receptor
Cirsimaritin
TQ0119
Synonym:
Target: GABA Receptor
Kavain
T5754
Synonym:
Target: NF-κB, GABA Receptor
Guvacine hydrochloride
T7557
Synonym:
Target: GABA Receptor
Jujuboside A
T3782
Synonym:
Target: transporter, GABA Receptor
6-Methylflavone
T8036
Synonym:
Target: GABA Receptor
(-)-Securinine
T3S2100
Synonym: Securinine
Target: GABA Receptor
Arecaidine hydrochloride
T5799
Synonym:
Target: Others
2'-O-Methylisoliquiritigenin
TN1217
Synonym:
Target: Dopamine Receptor, 5-HT Receptor, GABA Receptor
DL-Menthol
T2979
Synonym: Hexahydrothymol,(±)-Menthol
Target: GABA Receptor, AChE
Ginkgolide A
T2749
Synonym: BN-52020
Target: GABA Receptor, Endogenous Metabolite
6,2'-Dihydroxyflavone
T8268
Synonym:
Target: GABA Receptor
Bicuculline
T2850
Synonym: (+)-Bicuculline,d-Bicuculline
Target: GABA Receptor
Bemegride
T1396
Synonym: Bemegrid,3-Ethyl-3-methylglutarimide,Agipnon
Target: GABA Receptor
alpha-Asarone
T3698
Synonym: α-Asarone,trans-Asarone
Target: P450, GABA Receptor, HMG-CoA Reductase
Ginsenoside Rc
T2720
Synonym: Panaxoside Rc
Target: Others, TNF, GABA Receptor, Interleukin
Dihydroergotoxine mesylate
TMS0418
Synonym: Ergoloid mesylates
Target: GABA Receptor
Songorine
T5S1882
Synonym: Napellonine,Zongorine,Bullatine G
Target: Others, GABA Receptor
(-)-α-Pinene
TN1202
Synonym: (1S)-(-)-Alpha-Pinene
Target: Virus Protease, GABA Receptor, Endogenous Metabolite, Antibacterial
(+)-Kavain
T4590
Synonym: Kavain,L-KAWAIN,(R)-KAWAIN
Target: Calcium Channel, GABA Receptor, Sodium Channel, Monoamine Transporter
(2S)-6-Prenylnaringenin
TN1325
Synonym: 6-Prenylnaringenin,6-PN
Target: GABA Receptor
L-DABA
T7595
Synonym: L-2,4-Diaminobutyric acid,L-DAB HBR
Target: GABA Receptor, Endogenous Metabolite
Cholesterol myristate
T8040
Synonym: Cholesteryl myristate,Cholesteryl tetradecanoate
Target: Others, Potassium Channel, GABA Receptor, Endogenous Metabolite, AChR
3,4,5-Trimethoxycinnamic acid
T2983
Synonym: 3-(3,4,5-Trimethoxyphenyl)acrylic Acid,O-Methylsinapic acid
Target: GABA Receptor, Endogenous Metabolite
L-Cycloserine
T0710
Synonym: Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,(S)-4-Amino-3-isoxazolidone
Target: HIV Protease, GABA Receptor
α-Thujone
T8193
Synonym: Thujone,ALPHA-(-)-THUJONE
Target: Apoptosis, Reactive Oxygen Species, GABA Receptor, AChR, Parasite, Autophagy
p-Hydroxybenzaldehyde
T2S1814
Synonym: 4-Formylphenol,4-hydroxybenzaldehyde,p-Oxybenzaldehyde
Target: Transaminase, GABA Receptor, Endogenous Metabolite
Thiocolchicoside
T2S1464
Synonym: Thiocolchicine 2-glucoside analog,Coltramyl
Target: Others, GABA Receptor
Amentoflavone
T3417
Synonym: Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin
Target: Apoptosis, P450, Phospholipase, Reactive Oxygen Species, Opioid Receptor, COX, Antibacterial, RSV, Antifungal
Guvacine ethyl ester
TJS0123
Synonym: PT00442-2
Target: Others
(E)-3,4,5-Trimethoxycinnamic acid
TN2865
Synonym: O-Methylsinapic acid,3,4,5-Trimethoxy-trans-cinnamic acid,3,4,5-Trimethoxyphenylacrylic acid
Target: Others
(+)-BORNEOL
T5734
Synonym: d-Borneol
Target: GABA Receptor
(-)-borneol
T3741
Synonym: L-Borneol
Target: GABA Receptor
6-Methoxyflavanone
TN3174
Synonym: NSC50184
Target: GABA Receptor
pimpinellin
T5776
Synonym:
Target: Apoptosis, Anti-infection
β-Alanine
T0627
Synonym: beta-Alanine,3-Aminopropanoic acid,2-Carboxyethylamine
Target: GABA Receptor, Endogenous Metabolite
γ-Glu-Gly
T39359
Synonym: gamma-Glutamylglycine
Target: Amino Acids and Derivatives
Tramiprosate
T0883
Synonym: Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed
Target: Beta Amyloid, GABA Receptor
6-Hydroxyflavanone
TN1308
Synonym:
Target: Others, Lipoxygenase, COX, GABA Receptor
(R)-5-Oxopyrrolidine-2-carboxylic acid
T4814
Synonym: D-Pyroglutamic acid,(R)-(+)-2-Pyrrolidone-5-carboxylic acid
Target: Others, Endogenous Metabolite
Pyridoxal phosphate
T3578
Synonym: PLP,PAL-P,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate
Target: Reverse Transcriptase, Endogenous Metabolite
Phosphorylethanolamine
T4881
Synonym: O-Phosphorylethanolamine
Target: Others, Endogenous Metabolite
5-Aminovaleric acid
T5089
Synonym:
Target: Others, Endogenous Metabolite
Methyl eugenol
T3S2259
Synonym: 4-allylveratrole,eugenyl methyl ether,O-methyleugenol,Eugenol Methyl ether
Target: GABA Receptor
(-)-Corlumine
TN3702
Synonym:
Target: GABA Receptor
Guvacine
TN1717
Synonym:
Target: GABA Receptor
Guvacine hydrobromide
T80014
Synonym:
Target: GABA Receptor
Isohyenanchin
TN4298
Synonym:
Target: GABA Receptor

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPH-00857 ABAT Protein, Human, Recombinant (His & Myc & SUMO) Human E. coli
Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine. ABAT Protein, Hu...
TMPY-00587 GABARAP Protein, Human, Recombinant (His & MBP) Human E. coli
The Atg8/LC3/GABARAP family of proteins, a group that has structural homology with ubiquitin, connects with a large set of binding partners to function in macroautophagy (hereafter autophagy). GABARAP in tumorigenesis in...
TMPJ-00016 GABARAP Protein, Human, Recombinant (GST) Human E. coli
GABARAP Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37 KDa and the accession number is Q6IAW1.
TMPJ-00015 GABARAP Protein, Human, Recombinant (His & hFc) Human E. coli
GABARAP Protein, Human, Recombinant (His & hFc) is expressed in E. coli expression system with N-6xHis and C-Fc tag. The predicted molecular weight is 50 KDa and the accession number is Q6IAW1.
TMPY-03268 GABARAPL1 Protein, Human, Recombinant (His) Human E. coli
ATG8, also known as GABARAPL1, is a ubiquitin-like protein that has a crystal structure. ATG8 consists of a 5-stranded β-sheet, which is enclosed by two α-helices at one side and one α-helix at the other side and exhibit...
TMPY-03461 GABARAPL2 Protein, Human, Recombinant (His) Human E. coli
GATE-16, also known as ATG8, belongs to the MAP1 LC3 family. It is expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. GATE-16 is expressed at very low levels in lung, thymus and...
TMPY-03991 DBI Protein, Human, Recombinant (His) Human E. coli
The diazepam binding inhibitor (DBI), alternatively known as the acyl-CoA binding protein (ACBP), is involved in multiple biological actions. The polypeptide binds to the peripheral, or mitochondrial, benzodiazepine rece...
TMPH-01368 GABRP Protein, Human, Recombinant (His) Human E. coli
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of th...
TMPH-02149 ALDH5A1 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
TMPH-02492 DBI Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site lo...
TMPH-00890 DBI Protein, Human, Recombinant (aa 2-104, His) Human E. coli
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site lo...
TMPH-03235 DBI Protein, Rat, Recombinant (His & Myc) Rat E. coli
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site lo...
TMPY-00186 GHRH Protein, Human, Recombinant (hFc) Human HEK293 Cells
The role of hypothalamic growth hormone-releasing hormone (GHRH) in the release of growth hormone (GH) from the pituitary is well established. Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important...
TMPH-02564 CARNMT1 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of ...
TMPH-00627 GAD-alpha Protein, E. coli, Recombinant (His) E. coli E. coli
Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions...
TMPK-01233 LAMP5 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesi...
TMPK-01161 LAMP5 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesi...
TMPY-02091 GAD67 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Glutamate decarboxylase 1, also known as 67 kDa glutamic acid decarboxylase, Glutamate decarboxylase 67 kDa isoform and GAD1, is a member of thegroup II decarboxylase family. GAD1 is expressed in benign and malignant ...
TMPK-00659 LAMP5 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesi...
TMPK-01234 LAMP5 Protein, Human, Recombinant (His) Human HEK293 Cells
Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesi...
TMPH-03037 Alpha-cobratoxin Protein, Naja kaouthia, Recombinant (GST & His & Myc) Naja kaouthia E. coli
Monomer: binds with high affinity to muscular (alpha-1-beta-1-gamma-delta/CHRNA1-CHRNB1-CHRNG-CHRND) nAChR (tested on Torpedo californica, Kd=0.2-4.5 nM) and neuronal alpha-7/CHRNA7 nicotinic acetylcholine receptors (Kd=...
TMPY-00286 Neuropeptide Y Protein, Human, Recombinant (hFc) Human HEK293 Cells
NPY (Neuropeptide Y) is a Protein Coding gene. This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress ...
TMPH-01248 ADAR Protein, Human, Recombinant (His & SUMO) Human E. coli
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio...
ABAT Protein, Human, Recombinant (His & Myc & SUMO)
TMPH-00857
Species: Human
Expression System: E. coli
GABARAP Protein, Human, Recombinant (His & MBP)
TMPY-00587
Species: Human
Expression System: E. coli
GABARAP Protein, Human, Recombinant (GST)
TMPJ-00016
Species: Human
Expression System: E. coli
GABARAP Protein, Human, Recombinant (His & hFc)
TMPJ-00015
Species: Human
Expression System: E. coli
GABARAPL1 Protein, Human, Recombinant (His)
TMPY-03268
Species: Human
Expression System: E. coli
GABARAPL2 Protein, Human, Recombinant (His)
TMPY-03461
Species: Human
Expression System: E. coli
DBI Protein, Human, Recombinant (His)
TMPY-03991
Species: Human
Expression System: E. coli
GABRP Protein, Human, Recombinant (His)
TMPH-01368
Species: Human
Expression System: E. coli
ALDH5A1 Protein, Human, Recombinant (His)
TMPH-02149
Species: Human
Expression System: P. pastoris (Yeast)
DBI Protein, Mouse, Recombinant (His & Myc)
TMPH-02492
Species: Mouse
Expression System: E. coli
DBI Protein, Human, Recombinant (aa 2-104, His)
TMPH-00890
Species: Human
Expression System: E. coli
DBI Protein, Rat, Recombinant (His & Myc)
TMPH-03235
Species: Rat
Expression System: E. coli
GHRH Protein, Human, Recombinant (hFc)
TMPY-00186
Species: Human
Expression System: HEK293 Cells
CARNMT1 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02564
Species: Mouse
Expression System: E. coli
GAD-alpha Protein, E. coli, Recombinant (His)
TMPH-00627
Species: E. coli
Expression System: E. coli
LAMP5 Protein, Human, Recombinant (hFc)
TMPK-01233
Species: Human
Expression System: HEK293 Cells
LAMP5 Protein, Mouse, Recombinant (hFc)
TMPK-01161
Species: Mouse
Expression System: HEK293 Cells
GAD67 Protein, Human, Recombinant (His)
TMPY-02091
Species: Human
Expression System: Baculovirus Insect Cells
LAMP5 Protein, Cynomolgus, Recombinant (His)
TMPK-00659
Species: Cynomolgus
Expression System: HEK293 Cells
LAMP5 Protein, Human, Recombinant (His)
TMPK-01234
Species: Human
Expression System: HEK293 Cells
Alpha-cobratoxin Protein, Naja kaouthia, Recombinant (GST & His & Myc)
TMPH-03037
Species: Naja kaouthia
Expression System: E. coli
Neuropeptide Y Protein, Human, Recombinant (hFc)
TMPY-00286
Species: Human
Expression System: HEK293 Cells
ADAR Protein, Human, Recombinant (His & SUMO)
TMPH-01248
Species: Human
Expression System: E. coli
カタログ番号 製品名
L2610 Neurotransmitter Receptor Compound Library

1513 compounds
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening;