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Search Results for " catalytic "

ターゲット

Apoptosis Glutathione Peroxidase Autophagy

127

阻害剤

天然化合物

111

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T12189	NBDHEX		Apoptosis , Glutathione Peroxidase , Autophagy
	NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1) .		Apoptosis , Glutathione Peroxidase , Autophagy
T9884	EN523		Others
	EN523 targets non-catalytic allosteric cysteine C23 in K48 ubiquitin-specific deuquitinase OTUB1.		Others
T14505	BAY-524		Others
	BAY-524 is an inhibitor of Bub1(IC50 = 450 nM.human Bub1 in the presence of 2 mM ATP).		Others
T5363	Tempo	2,2,6,6-Tetramethylpiperidinooxy	Free radical scavengers , Reactive Oxygen Species , DNA/RNA Synthesis , Mitochondrial Metabolism
	Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy.
T39341	FCPR03		PDE
	FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively. FCPR03 has neuroprotective, anti-inflammatory, and antidepr...		PDE
T63049	CHD1Li 6.11		Others
	CHD1Li 6.11 is a potent inhibitor of oncogenic CHD1L, acting on the cat-CHD1L recombinant protein (IC50: 3.3 μM). CHD1Li 6.11 is an orally active antitumour agent that significantly reduces the tumour volume of CRC xenog...		Others
T15069	DBCO-PEG4-Biotin	ADIBO-NH-PEG2-Biotin	Others
	DBCO-PEG4-Biotin (ADIBO-NH-PEG2-Biotin) is an azadibenzocyclooctyne-biotin derivative containing a biotin moiety and 4 PEGs.DBCO-PEG4-Biotin is a versatile biotinylation reagent that introduces a portion of biotin into ...		Others
T9961	L82-G17		DNA/RNA Synthesis
	L82-G17 is an uncompetitive LigI-selective inhibitor in human cells with utility as a probe of the catalytic activity and cellular functions of LigI.		DNA/RNA Synthesis
T22380	Nor-benzetimide		Others , AChR
	Norbenzetimide, an organic compound, is prepared from benzetimide by catalytic transfer hydrogenolysis.		Others , AChR
T5461	GNE-6640		DUB
	GNE-6640 is a non-covalent inhibitor targeting ubiquitin specific peptidase 7 (USP7), exhibiting IC50 values of 0.75 μM for full-length USP7, 0.43 μM for the USP7 catalytic domain, 20.3 μM for full-length USP43, and 0.23...		DUB
T60169	BLU0588		Others
	BLU0588 is a selective PRKACA inhibitor. BLU0588 inhibits PRKACA catalytic activity with a half-maximal inhibitory concentration (IC50) of 1 nM.		Others
T5097	Ezatiostat	TER199(free base),TLK199	Apoptosis , Glutathione Peroxidase , GST
	Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity.		Apoptosis , Glutathione Peroxidase , GST
T28416	PIK-108	PIK 108,PIK108	PI3K
	PIK-108 is an allosteric inhibitor of phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunits β and δ (PI3Kβ/δ).		PI3K
T15351	FT827		DUB
	FT827 is a covalent inhibitor of selective ubiquitin-specific protease 7 (USP7) (Ki=4.2 µM, Kd=7.8 µM) targeting the catalytic center of the autoinhibitory apolipoprotein form of USP7 for cancer research.		DUB
T9262	MAT2A inhibitor 4		Others , Methionine Adenosyltransferase (MAT)
	MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancer research.		Others , Methionine Adenosyltransferase (MAT)
T23819	Braco-19 trihydrochloride	BRAC-O19,BRACO19 hydrochloride,BRACO19 3HCl,BRACO 19,BRACO19 HCl	Telomerase
	Braco-19 trihydrochloride (BRACO19 3HCl) is an inhibitor of telomerase and prevents the capping and catalytic action of telomerase. Braco-19 trihydrochloride inhibits HAdV virus replication.		Telomerase
T22086	HA 155	Autotaxin Inhibitor IV	PDE
	HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.		PDE
T14073	A-485		Epigenetic Reader Domain , Histone Acetyltransferase
	A-485 is a potent and selective catalytic p300/CBP inhibitor(IC50s of 9.8 nM and 2.6 nM for p300 and CBP, respectively).		Epigenetic Reader Domain , Histone Acetyltransferase
T2661	TGX-221	TGX221	PI3K
	TGX-221, an effective, specific, and cell membrane permeable inhibitor of the PI3K p110β catalytic subunit, is utilized for cancer treatment.		PI3K
T8864	Thymidylate Kinase Inhibitor, YMU1		Others
	YMU1 is a human thymidylate kinase (hTMPK) inhibitor. YMU1 stabilizes the conformation of ligand-induced degradation (LID) region of hTMPK and blocks the catalytic site or ATP-binding site.		Others
T8813	Tetrakis (4-carboxyphenyl) porphyrin	TCPP,Tetracarboxyphenylporphine	Others
	Tetrakis (4-carboxyphenyl) porphyrin (TCPP) plays the role of a metal remover.Tetrakis (4-carboxyphenyl) porphyrin is a fabricated three dimensional Ru polymer complex. It can be grafted on SiO2/Nb2O5 substrate and subse...		Others
T1994	Pictilisib	RG7321,GDC-0941	Apoptosis , PI3K , Autophagy
	Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).		Apoptosis , PI3K , Autophagy
T1894	Idelalisib	GS-1101,CAL-101	PI3K , Autophagy
	Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 nM). The selectivity for p110δ is 40- to 300-fold than p110α/β/γ.		PI3K , Autophagy
T7541	PTP inhibitor 1	PTP Inhibitor II	Phosphatase
	PTP inhibitor 1 is an inhibitor of cell-permeable protein tyrosine phosphatase (PTP) that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)),with Ki of128 μM.		Phosphatase
T14133	AEOL-10150 pentachloride		Others
	AEOL-10150 pentachloride is a metalloporphyrin catalytic antioxidant. AEOL-10150 pentachloride also is a superoxide dismutase mimetic. Which protects lungs from radiation-induced injury.		Others
T6326	BMS-345541	BMS-345541 free base,IKK Inhibitor III,BMS345541	IκB/IKK
	BMS-345541 (IKK Inhibitor III) is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.		IκB/IKK
T6324	(E/Z)-BIX02188	334949-59-6	ERK , MEK , TGF-beta/Smad
	BIX02188 is a specific MEK5 inhibitor (IC50: 4.3 nM), also inhibits ERK5 catalytic activity (IC50: 810 nM), and does not inhibit closely related kinases MEK1/2, JNK2, and ERK2.		ERK , MEK , TGF-beta/Smad
T3623	Cobimetinib	RG7420,XL518,GDC-0973	Apoptosis , MEK
	Cobimetinib (GDC-0973) is a selective inhibitor of mitogen-activated protein kinase kinase (MEK) (IC50: 0.9 nM). Cobimetinib specifically binds to and inhibits the catalytic activity of MEK1, resulting in inhibition of e...		Apoptosis , MEK
T39217	PKA-IN-1		PKA
	PKA-IN-1 is a selective and potent cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor (IC50: 0.03 μM).PKA-IN-1 can be used to study diseases of the immune system.		PKA
T14052	5-IAF	5-Iodoacetamidofluorescein
	5-IAF is a fluorescein derivative of indoleacetamide, a fluorescent probe that can be used to label proteins and others containing free thiols (cysteine side chains). 5-IAF can label the catalytic (alpha) subunit of dog ...
T67844	RBN-3143		PARP
	RBN-3143 is a potent and inhibitor of NAD+-competitive catalytic PARP14 (IC50= 4 nM). RBN-3143 inhibits ADP-ribosylation mediated by PARP14 and stabilizes PARP14 in cell lines. RBN-3143 exhibits research potential of lun...		PARP
T37571	4-Methylumbelliferyl-β-D-Glucopyranoside	MU-GLU,4-MUG,4-MU-GLU,4-MU-β-Gluc	Others
	4-Methylumbelliferyl-β-D-Glucopyranoside (4-MU-GLU) is used in the GCase activity assay based on the catalytic hydrolysis of 4-methylumbelliferyl β-D-glucopyranoside that releases the highly fluorescent 4-methylumbellife...		Others
T16333	NKY80	Adenylyl cyclase type V Inhibitor	Adenylyl cyclase
	NKY80 regulates the adenylyl cyclase catalytic activity in heart and lung tissues. NKY80 is a non-competitive inhibitor of adenylyl cyclase type V isoform (IC50s: 8.3 µM, 132 µM, and 1.7 mM for type V, III and II, respe...		Adenylyl cyclase
T50029	2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine	2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine	Others
	2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine (2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine) is a heterocyclic compound. It inhibits monoamine oxidase, resulting in elevated monoamine levels in the body. It can...		Others
T60278	Tyrosinase-IN-2		Tyrosinase
	Tyrosinase-IN-2 (compound 67) is a potent inhibitor of tyrosinase, a copper-containing metalloenzyme pivotal for the catalytic step that limits the rate in melanin biosynthesis and enzymatic browning processes. This comp...		Tyrosinase
T23046	N-tert-butyl-α-Phenylnitrone	(Z)-N-benzylidene-2-Methylpropan-2-aMine oxide	ROS , COX
	N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity. N-tert-butyl-α-Phenylnitrone((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) possesses potent reactive oxyge...		ROS , COX
T60130	USP5-IN-1		DUB
	USP5-IN-1 (compound 64) is a potent deubiquitinase USP5 inhibitor, which binds to the USP5 ZnF-UBD with a KD of 2.8 μM and is selective over nine proteins containing structurally similar ZnF-UBD domains. USP5-IN-1 inhibi...		DUB
T7084	2-Bromo-4'-hydroxyacetophenone	SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide	Phosphatase
	2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SH...		Phosphatase
T11807	L002		Others , Histone Acetyltransferase , STAT
	L002, a potent, cell-permeable, reversible, and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM, directly binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain. By ...		Others , Histone Acetyltransferase , STAT
T27453	GSK1733953A	DG70	Antibacterial
	GSK1733953A can be used as a small molecule Mycobacterium tuberculosis respiration inhibitor with an inhibitory effect on MenG activity and an IC50 value of 2.6 ± 0.6 μM.GSK1733953A is a selective biphenylbenzamide with ...		Antibacterial
T25893	NU/ICRF 500
	NU/ICRF 500 is a novel anthracenyl-amino acid catalytic inhibitor of topoisomerase II.
T25140	BCH 2763	BCH2763,BCH-2763
	BCH 2763 is an effective, selective bifunctional thrombin inhibitor that blocks both the anion binding exosite and the active catalytic site.
T29196	YU142670	YU 142670,YU-142670
	YU142670 is a selective inhibitor of OCRL1/INPP5F and OCRL2/INPP5B by targeting OCRL catalytic domain.
T27145	Demethoxyviridin	DMV
	Demethoxyviridin is a potent inhibitor of mammalian Ptdlns 3-kinase, it binds to the catalytic subunit (p110) of the enzyme. Demethoxyviridin is also an antifungal agent.
T12621L	FT671		DUB
			DUB
T31171	D714	D-714,D 714
	D714 is a weakly conserved palm subdomain residue (located far from the catalytic center) that, when replaced by alanine, impains the enzyme's replication in vivo and in vitro.
T11552	HDDAH-1-IN-1		Others
	hDDAH-1-IN-1 is a selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) (Ki: 18 μM).		Others
T70591	PF1070A
	PF1070A is a natural cyclic tetrapeptide HDAC Inhibitor through the inhibition of PfHDAC1 catalytic activity, potently inducing the synthesis of metallothionein.
T70465	Mf 268
	Mf 268 is a pseudo-reversible carbamate-type inhibitor which interacts with the catalytic and regulatory anionic site of the enzyme.
T12209	Netropsin dihydrochloride		Others
	Netropsin dihydrochloride is a small-molecule MGB (minor-groove binder), inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and ...		Others

Compounds

NBDHEX

T12189

Synonym:

Target: Apoptosis, Glutathione Peroxidase, Autophagy

Synonym: 2,2,6,6-Tetramethylpiperidinooxy

Target: Free radical scavengers, Reactive Oxygen Species, DNA/RNA Synthesis, Mitochondrial Metabolism

Synonym: ADIBO-NH-PEG2-Biotin

Target: DNA/RNA Synthesis

Synonym: TER199(free base),TLK199

Target: Apoptosis, Glutathione Peroxidase, GST

PIK-108

T28416

Synonym: PIK 108,PIK108

Target: Others, Methionine Adenosyltransferase (MAT)

Braco-19 trihydrochloride

T23819

Synonym: BRAC-O19,BRACO19 hydrochloride,BRACO19 3HCl,BRACO 19,BRACO19 HCl

Target: Telomerase

HA 155

T22086

Synonym: Autotaxin Inhibitor IV

Target: Epigenetic Reader Domain, Histone Acetyltransferase

Thymidylate Kinase Inhibitor, YMU1

T8864

Synonym:

Target: Others

Tetrakis (4-carboxyphenyl) porphyrin

T8813

Synonym: TCPP,Tetracarboxyphenylporphine

Target: Others

Pictilisib

T1994

Synonym: RG7321,GDC-0941

Target: Apoptosis, PI3K, Autophagy

Idelalisib

T1894

Synonym: GS-1101,CAL-101

Target: PI3K, Autophagy

PTP inhibitor 1

T7541

Synonym: PTP Inhibitor II

Target: Phosphatase

AEOL-10150 pentachloride

Synonym: BMS-345541 free base,IKK Inhibitor III,BMS345541

Target: ERK, MEK, TGF-beta/Smad

Cobimetinib

T3623

Synonym: RG7420,XL518,GDC-0973

Target: Apoptosis, MEK

Synonym: 5-Iodoacetamidofluorescein

4-Methylumbelliferyl-β-D-Glucopyranoside

T37571

Synonym: MU-GLU,4-MUG,4-MU-GLU,4-MU-β-Gluc

Target: Others

NKY80

T16333

Synonym: Adenylyl cyclase type V Inhibitor

Target: Adenylyl cyclase

2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine

T50029

Synonym: 2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine

N-tert-butyl-α-Phenylnitrone

T23046

Synonym: (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide

2-Bromo-4'-hydroxyacetophenone

T7084

Synonym: SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide

Target: Others, Histone Acetyltransferase, STAT

GSK1733953A

T27453

Synonym: DG70

Target: Antibacterial

Synonym: BCH2763,BCH-2763

Target:

YU142670

T29196

Synonym: YU 142670,YU-142670

Netropsin dihydrochloride

T12209

Synonym:

Target: Others

カタログ番号	製品名	別名	ターゲット
T4741	N-Formylglycine		Others , Endogenous Metabolite
	N-Formylglycine is a simple dipeptide and a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.		Others , Endogenous Metabolite
T5855	Edrophonium chloride		AChE
	Edrophonium chloride is an acetylcholinesterase (AChE) inhibitor that is known to prevent the breakdown of the neurotransmitter acetylcholine by binding specifically to its catalytic site.		AChE
T8072	S-Methyl-L-cysteine	S-Methylcysteine	Antioxidant , Reactive Oxygen Species
	S-Methyl-L-cysteine (S-Methylcysteine) is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with neuroprotective, antioxidative, and anti-...		Antioxidant , Reactive Oxygen Species
T6830	Epoxomicin	BU-4061T,BU-4061T,Aids010837	Apoptosis , Proteasome
	Epoxomicin (BU-4061T,Aids010837) is a selective proteasome inhibitor with anti-inflammatory activity, inhibits primarily the CH-L activity of the 20S proteasome, while T-L and PGPH catalytic activities are also inhibited...		Apoptosis , Proteasome
TWO2759	Thymine	5-methyluracil	Others , Endogenous Metabolite
	One of the pyrimidine bases of living matter. Derivation: Hydrolysis of deoxyribonucleic acid, from methylcyanoacetylurea by catalytic reduction. Use: Biochemical research. Thymine (5-methyluracil) is a pyrimidine nucleo...		Others , Endogenous Metabolite
T4839	Ac-Ala-OH	N-Acetylalanine,N-Acetyl-L-alanine	Others , Endogenous Metabolite
	Ac-Ala-OH (N-Acetyl-L-alanine) is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4 chain, HIV-1 Rev binding pro...		Others , Endogenous Metabolite
T38108	Fulvic Acid		Antioxidant , PDE
	Fulvic Acid is a natural product of humus produced by microorganisms in soil, sediment or aquatic environments. Fulvic acid is a phenolic acid and fungal metabolite isolated from Penicillium for the first time. Fulvic Ac...		Antioxidant , PDE
T4858	4-Hydroxyphenylpyruvic acid	4-Hydroxyphenylpyruvic acid	Endogenous Metabolite
	4-Hydroxyphenylpyruvic acid is an enzyme inhibitor.4-Hydroxyphenylpyruvic acid (4-HPPA) is a keto acid that is involved in the tyrosine catabolism pathway. It is a product of the enzyme (R)-4-hydroxyphenyllactate dehydro...		Endogenous Metabolite
T70725	Motuporin
	Motuporin is an inhibitor of type-1 and type-2A protein phosphatase catalytic subunits (PP-1c and PP-2Ac).
TN4173	Guajadial C		Topoisomerase
	Guajadial C acts as a Top1 catalytic inhibitor and can delay Top1 poison-mediated DNA damage. It shows cytotoxicity against five human cancer cell lines.		Topoisomerase
TN5348	Guajadial F
	Guajadial F acts as a Top1 catalytic inhibitor and can delay Top1 poison-mediated DNA damage. Guajadial F shows cytotoxicity against five human cancer cell lines.
T14196	Alternariol		Others
	Alternariol (AOH), a mycotoxin synthesized by Alternaria species, displays numerous therapeutic and biological effects, including phytotoxic, cytotoxic, anti-HIV, anti-cancer, and anti-microbial properties. It functions ...		Others
TN6514	2-Carboxybenzaldehyde
	The major peak of 2-Carboxybenzaldehyde reductase activity in human liver co-purifies with hAFAR protein. Sulphydryl substances and some proteins play important roles in preserving the molecular and catalytic properties ...
T40611	(E)-Dehydrodiconiferyl alcohol
	(E)-Dehydrodiconiferyl alcohol is a potent dual inhibitor of hCA IX and hCA XII, effectively impeding the catalytic activity of both carbonic anhydrase isoforms. Additionally, (E)-Dehydrodiconiferyl alcohol exerts inhibi...
TN4172	Guajadial B		Topoisomerase
	Guajadial B acts as a Top1 catalytic inhibitor and delays Top1 poison-mediated DNA damage. Guajadial B shows cytotoxicities against five human cancer cell lines, it is the most effective having an IC50 value of 150 nM to...		Topoisomerase
T72645	Norbatzelladine L
	Norbatzelladine L, an inhibitor of both the catalytic and functional activities of the Pdr5p transporter, suppresses Pdr5p ATPase activity with an IC50 of 3.8 µM. Additionally, it exhibits antifungal, antiparasitic, anti...
T16332	NKH477	Colforsin dapropate hydrochloride	NMDAR
	NKH477 is a novel water-soluble forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 shows an antiproliferative effect in vivo with an altered cyt...		NMDAR
T37055	Cytostatin
	Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cel...
T35415	α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)
	α-D-Glucose-1,6-bisphosphate is abis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate syntha...

天然物製品

N-Formylglycine

T4741

Synonym:

Target: Others, Endogenous Metabolite

Synonym: S-Methylcysteine

Target: Antioxidant, Reactive Oxygen Species

Epoxomicin

T6830

Synonym: BU-4061T,BU-4061T,Aids010837

Target: Apoptosis, Proteasome

Thymine

TWO2759

Synonym: 5-methyluracil

Target: Others, Endogenous Metabolite

Ac-Ala-OH

T4839

Synonym: N-Acetylalanine,N-Acetyl-L-alanine

Target: Others, Endogenous Metabolite

Fulvic Acid

T38108

Synonym:

Target: Antioxidant, PDE

4-Hydroxyphenylpyruvic acid

T4858

Synonym: 4-Hydroxyphenylpyruvic acid

Target: Endogenous Metabolite

Target: Topoisomerase

2-Carboxybenzaldehyde

TN6514

Synonym:

Target:

(E)-Dehydrodiconiferyl alcohol

Target: Topoisomerase

Synonym: Colforsin dapropate hydrochloride

α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)

T35415

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02869	MMP-12 Protein, Human, Recombinant (catalytic domain)	Human	E. coli
	Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPY-01186	Argonaute-2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Argonaute-2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 99 kDa and the accession number is Q9UKV8.
TMPY-02130	Argonaute-2 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Argonaute-2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 99 kDa and the accession number is Q8CJG0.
TMPH-01029	CAPN1 Protein, Human, Recombinant (His)	Human	E. coli
	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His...
TMPJ-00944	PPP1CC Protein, Human, Recombinant (His)	Human	E. coli
	Serine/Threonine-Protein Phosphatase PP1-Υ Catalytic Subunit (PPP1CC) is a member of the PPP phosphatase family. It is essential for cell division, participates in the regulation of glycogen metabolism, muscle contractil...
TMPY-02311	AGO3 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Argonaute (Ago) protein family plays a key role in the RNA interference (RNAi) process in different insects including Lepidopteran. AGO3 also coexists and interacts with Armitage in the mitochondrial fraction. Furthermo...
TMPH-01031	CAPN2 Protein, Human, Recombinant (His)	Human	E. coli
	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cle...
TMPH-00476	DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc)	Dictyostelium discoideum	E. coli
	DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc) is expressed in E. coli.
TMPY-01308	AGO1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Protein argonaute-1, also known as eukaryotic translation initiation factor 2C 1, EIF2C1, and AGO1, is a member of the argonaute family and ago subfamily. Protein argonaute-1 in humans is encoded by the EIF2C1 gene. Th...
TMPY-03339	NAA10/ARD1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	NAA10/ARD1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 54 kDa and the accession number is P41227.
TMPY-02963	Calcineurin A/PPP3CA Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	PPP3CA, also known as protein phosphatase 2B, is a member of the PPP phosphatase family, PP-2B subfamily. It is the alpha catalytic subunit of protein phosphatase 2B (PP2B). PP2B is a holoenzyme that is comprised of a ca...
TMPY-02050	DDOST Protein, Human, Recombinant	Human	E. coli
	The enzyme oligosaccharyltransferase (dolichyl-diphosphooligosaccharide-protein glycosyltransferase) (DDOST), or 48-kDa subunit (OST48) is one of the catalytic subunits in this complex, exerts a typical type I membrane t...
TMPH-01171	CDK5 Protein, Human, Recombinant	Human	E. coli
	CDK5 Protein, Human, Recombinant is expressed in E. coli.
TMPY-04266	NAA10/ARD1 Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	NAA10/ARD1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 26.6 kDa and the accession number is P41227.
TMPH-02557	CAPN1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-388' and 'His...
TMPY-04125	PTP1B Protein, Human, Recombinant (His)	Human	E. coli
	PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c...
TMPY-02585	Acid sphingomyelinase/SMPD1 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Sphingomyelin phosphodiesterase 1 (SMPD1) , also known as ASM ( acid sphingomyelinase ), is a member of the acid sphingomyelinase family of enzymes. Three isoforms have been identified, isoform 1 is 631 amino acids (aa) ...
TMPY-00570	Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyro...
TMPY-02801	PHGDH Protein, Human, Recombinant (His)	Human	E. coli
	PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the ...
TMPY-02707	PAH Protein, Human, Recombinant (415 Asn/Asp, His)	Human	Baculovirus Insect Cells
	PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding si...
TMPY-00203	LOXL2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 ...
TMPY-04548	CDK4 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	CDK4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cel...
TMPY-02185	Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ...
TMPY-01104	Coagulation factor XI/F11 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p...
TMPH-02530	ATP5B Protein, Mouse, Recombinant (His & Myc & SUMO)	Mouse	E. coli
	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respirator...
TMPY-03609	ATP5D Protein, Human, Recombinant (His)	Human	E. coli
	ATP5D is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synth...
TMPJ-01309	PKI-Beta Protein, Human, Recombinant (His)	Human	E. coli
	cAMP-Dependent Protein Kinase Inhibitor β (PKI-β) is a member of the PKI family. As a member of the cAMP-dependent protein kinase inhibitor family,It has been shown that PKI-β is an extremely potent competitive inhibitor...
TMPH-03453	GPI3 Protein, S. cerevisiae, Recombinant (His & Myc)	Saccharomyces cerevisiae	E. coli
	Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. GPI3 Protein, S. cerevisiae, Recombinant (His & My...
TMPH-00015	Abrin-d Protein, Abrus precatorius, Recombinant (His & Myc)	Abrus precatorius	E. coli
	The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA.; The B chain is a galactose-specific lectin th...
TMPK-01308	TAG-72 Protein, Canine, Recombinant (His)	Canine	E. coli
	The guanine-N7 methyltransferase domain of vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit and a stimulatory subunit. Cap (guanine-N7) methylation is an essential step in eukaryal mRNA...
TMPY-02978	ABHD14B Protein, Human, Recombinant (His)	Human	E. coli
	ABHD14B belongs to the AB hydrolase superfamily, ABHD14 family. It can be detected in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, placenta, lung, liver, skeletal mu...
TMPY-04557	PHKG1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform, also known as Phosphorylase kinase subunit gamma-1 and PHKG1, is a member of the protein kinase superfamily and CAMK Ser/Thr protein kinase family. P...
TMPH-00516	StxA2 Protein, Enterobacteria phage 933W, Recombinant (E189K, His & Myc)	Enterobacteria phage 933W	E. coli
	The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the cata...
TMPH-01665	TIMP3 Protein, Human, Recombinant (His)	Human	E. coli
	Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to ac...
TMPJ-01289	TIMP-4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene, belongs to the protease inhibitor I35 (TIMP) family. The protein complexes with metalloproteinases (such as collagenases) and irreve...
TMPY-02595	DUSP14 Protein, Human, Recombinant (His & MBP)	Human	E. coli
	Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine phosphatases (PTP) families that can dephosphorylate bothe phosph...
TMPH-03326	MASP2 Protein, Rat, Recombinant (His)	Rat	Baculovirus Insect Cells
	Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the ...
TMPY-03788	ATP1B1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ATP1B1 belongs to the family of Na+/K+and H+/K+-ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. ATP1B1 is a subunit of Na+/K+-ATPase. Na+/K+-ATPase is an integral membrane protein responsible for es...
TMPH-02186	TERT Protein, Human, Recombinant (His)	Human	E. coli
	Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic c...
TMPY-06416	SARS-CoV-2 NSP8 Protein	SARS-CoV-2	E. coli
	NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarka...
TMPH-00013	Abrin-a Protein, Abrus precatorius, Recombinant (Yeast, His)	Abrus precatorius	P. pastoris (Yeast)
	The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. Abrin-a is more toxic than ricin.; The B chain...
TMPH-03195	Protein archease, Pyrococcus horikoshii, Recombinant (His & Myc)	Pyrococcus horikoshii	E. coli
	Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP s...
TMPY-05749	SARS-CoV-2 NSP8 Protein (Avi)	SARS-CoV-2	E. coli
	NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarka...
TMPJ-01092	MGAT2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal...
TMPJ-01229	SUMF1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Human Sulfatase Modifying Factor 1 (SUMF1) is a 42kDa protein. SUMF1 is a Ca2+-binging member of the sulfatase-modifying factor family. SUMF1 is a soluble ER lumenal glycoprotein, it converts inactive sulfatases into an ...
TMPH-00012	Abrin-a Protein, Abrus precatorius, Recombinant (E. coli, His)	Abrus precatorius	E. coli
	The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. Abrin-a is more toxic than ricin.; The B chain...
TMPK-01533	HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPH-03707	Viscumin Protein, Viscum album, Recombinant (His)	Viscum album	P. pastoris (Yeast)
	The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. The B chain binds to cell receptors and probab...
TMPK-01502	HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPJ-00868	PFKFB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate...
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