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ターゲット

阻害剤

天然化合物

559

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T7776	ADH-503	GB1275	Complement System
	ADH-503 (GB1275) is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression.		Complement System
T3100	GSK-J4	GSK J4 HCl	Apoptosis , Histone Demethylase
	GSK-J4 (GSK J4 HCl) is a potent H3K27me3 demethylase inhibitor, with IC50s of 8.6 μM and 6.6 μM towards KDM6B and KDM6A respectively. It is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX wit...		Apoptosis , Histone Demethylase
T4383	GSK-J4 Hydrochloride	GSK J4 HCl,GSK J4 HCl (1373423-53-0 free base)	Histone Demethylase
	GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. is an ethyl ester derivative of the GSK-J1 with an IC50 value greater than 50 μM in vitro.		Histone Demethylase
TP1540	Jagged-1 （188-204）	Jagged-1 188-204	Gamma-secretase
	Jagged-1 （188-204）is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolay...		Gamma-secretase
T13379	(Z)-Leukadherin-1	ADH-503 free base	Complement System
	(Z)-Leukadherin-1 (ADH-503 free base) is an allosteric agonist of CD11b.		Complement System
T2018	Apilimod	STA 5326	IL Receptor , PI3K , Interleukin
	Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.		IL Receptor , PI3K , Interleukin
T25450L	GGTI 2147 FA	GGTI2147 FA,GGTI-2147 FA,GGTI 2147 FA(191102-87-1 Free base)	Others
	GGTI 2147 FA, a selective GGT inhibitor, abolishes bicuculline-induced increase in dendritic spine density in hippocampal experiments and may reduce learning and memory abilities in mice.		Others
T72482	Dazostinag disodium		STING
	Dazostinag disodium (TAK-676) is a novel stimulator of interferon genes (STING) agonist and immune system modulator with antitumor activity that activates dendritic cells, natural killer cells, and T cells.		STING
TP1895L1	KYL acetate(676657-00-4 free base)		Ephrin Receptor
	KYL acetate is an EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP...		Ephrin Receptor
T6964	Resiquimod	R848,S28463	HCV Protease , TLR
	Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and acti...		HCV Protease , TLR
T27160	DG026	DG 026,DG-026
	DG026 is a IRAP inhibitor. DG026 ables to selectively downregulate IRAP-dependent cross-presentation by dendritic cells but leave ERAP1-dependent cross-presentation unaffected.
T26828	BIT225	BIT 225,BIT-225
	BIT-225 is a NCp7 zinc finger inhibitor. BIT225 inhibits HIV-1 replication in myeloid dendritic cells. BIT225 inhibits HIV-1 release from human macrophages. BIT225 inhibits bovine viral diarrhea virus in vitro and shows ...
T40452	N-Acetylpsychosine	N-Acetylpsychosine,C2 Galactosylceramide (d18:1/2:0)
	N-Acetylpsychosine, also known as α-galactosylated C2-ceramide (d18:1/2:0), exhibits immunostimulatory properties. This compound, N-Acetylpsychosine, holds potential as a valuable tool for studying the mechanisms of apop...
T76771	Pivekimab
	Pivekimab, a human IgG1 monoclonal antibody, targets interleukin 3 (IL-3) and CD123. It is utilized in researching blastocytic plasmacytoid dendritic cell tumor (BPDCN) [1].
T78079	NF546 hydrate		P2Y Receptor
	NF546 (hydrate), a selective non-nucleotide P2Y11 agonist, exhibits a pEC50 value of 6.27 and induces interleukin-8 secretion from human monocyte-derived dendritic cells [1].		P2Y Receptor
T37162	8-hydroxy Efavirenz
	8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B...
TP1895	KYL peptide	KYL
	KYL peptide is an EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP...
T38946	C8 Dihydroceramide	C8 Dihydroceramide
	C8 Dihydroceramide acts as a negative control for C8 Ceramide, a cell-permeable analog of natural ceramides. C8 Ceramide, also known as N-Octanoyl-D-erythro-sphingosine, exhibits potent chemotherapeutic properties and an...
T76767	Daxdilimab
	Daxdilimab, an anti-ILT7 monoclonal antibody, targets the ILT7 cell surface molecule exclusive to pDC dendritic cells. It shows potential for treating acute lung injury (ALI) in COVID-19 infected patients, as indicated i...
T80918	Tuparstobart	Incagn-02385
	Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on activated T cells, NK cells, B cells, and plasmacytoid dendritic ...
T74706	Vidutolimod
	Vidutolimod (CMP-001), a CpG-A oligodeoxynucleotide and Toll-like receptor 9 (TLR9) agonist, activates plasmacytoid dendritic cells (pDCs) and induces the release of interferon alpha (IFNα), initiating a series of anti-t...
T37898	UDP-α-D-Glucose (sodium salt hydrate)
	UDP-α-D-Glucose is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It has been shown to bind the P2Y14receptor (EC50= 0.35 μM), an atypical P2Y receptor involved in the activation ...
T71325	ANA-773
	ANA773 is a Toll-like Receptor 7 (TLR7) agonist prodrug with potential immunostimulating activity. Upon oral administration, ANA773 is metabolized into its active form that binds to and activates TLR7, thereby stimulatin...
T74969	Phospholipid PL1
	Phospholipid PL1, a phospholipid-derived nanoparticle, efficiently delivers costimulatory receptor mRNA (CD137 or OX40) to T cells, thereby inducing the activation of immune cells such as T cells and dendritic cells (DCs...
T36868	4-oxo Docosahexaenoic Acid
	4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF,...
T76023	Jagged-1 (188-204) (TFA)
	Jagged-1 (188-204) TFA, a fragment of the Jagged-1 (JAG-1) protein, acts as a Notch agonist. This compound is significantly present in both cultured and primary multiple myeloma (MM) cells, where JAG-1 facilitates the ma...
T36452	1-Arachidonoyl Lysophosphatidic Acid (ammonium salt)
	1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is...
T63553	HPK1-IN-28
	HPK1-IN-28 is a potent inhibitor of HPK1, a negative regulator of dendritic cell (DC), T-cell and B-cell activation responses. HPK1-IN-28 is effective in enhancing anti-tumor immunity in humans and has shown research pot...
T69944	NLG802 HCl
	NLG802 is an orally bioavailable prodrug of indoximod, a methylated tryptophan, with immune checkpoint inhibitory and antineoplastic activities. Upon oral administration, the indoximod prodrug NLG802 is converted to indo...
T79707	Cholicamideβ		Necroptosis
	Cholicamideβ (compound 6), a self-assembling small molecule cancer vaccine adjuvant, forms low cytotoxicity virus-like particles and upon binding to peptide antigens, enhances dendritic cell-mediated antigen presentation...		Necroptosis
T78596	CAD031
	CAD031, a more active derivative of the Alzheimer's disease (AD) targeting agent J147, exhibits neuroprotective and memory-enhancing properties. It has been shown to enhance memory, improve dendritic structure, and stimu...
T35773	Gliotoxin-13C13	Gliotoxin-13C13
	Gliotoxin-13C13is intended for use as an internal standard for the quantification of gliotoxin by GC- or LC-MS. Gliotoxin is an immunosuppressive mycotoxin produced by pathogenic strains ofAspergillusand other fungi with...
T63270	HPK1-IN-29
	HPK1-IN-29 is a potent inhibitor of HPK1, in which hematopoietic progenitor kinase 1 (HPK1) is a negative regulator of the activation response of dendritic cells (DCs), T cells and B cells. HPK1-IN-29 is able to enhance ...
T69523	BMS-681
	BMS-681 is an orthosteric antagonist of chemokine receptor 2 (CCR2) that forms a ternary complex with CCR2 and its allosteric antagonist, CCR2-RA-[R]. Together, the complex inhibits chemokine binding with BVMS-681 in the...
T37273	BLX3887
	BLX3887 is an inhibitor of 15-lipoxygenase type 1 (15-LO-1; IC50 = 32 nM in a cell-free enzyme assay).1 It is selective for 15-LO-1 over 15-LO-2, which it does not inhibit, 5-LO (IC50 = 472 nM), and 12-LO (IC50 = 3,310 n...
T70174	Pirlindole-d4 HCl
	Pirlindole-d4 is intended for use as an internal standard for the quantification of pirlindole by GC- or LC-MS. Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor. It is selective for MAO-A ov...
T79608	DPP		JAK
	DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, demonstrating antiproliferative activity. It activates caspase-3 and cleaved poly ADP-ri...		JAK
T77090	Mitazalimab
	Mitazalimab (ADC-1013; JNJ-64457107) is an FcγR-dependent CD40 agonist that exhibits directed activity against tumors. By activating antigen-presenting cells, such as dendritic cells (DC), it triggers the initiation of t...
T27051	CM-414	CM 414,CM414
	CM-414 is a dual inhibitor of HDACs and PDE5 for the Treatment of Alzheimer’s Disease (IC50 values of 60 nM, 310 nM, 490 nM, 322 nM, and 91 nM against PDE5, HDAC1, HDAC2, HDAC3, and HDAC6, respectively). Chronic treatmen...
T79609	STAT3-IN-18		JAK
	STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the JAK2-STAT3 pathway in breast cancer (BC) cells and exhibits anti-proliferative properties. It promotes apoptos...		JAK
T83846	HOXB7 (8-25) TFA	Homeobox B7 (8-25)
	HOXB7 (8-25), a peptide fragment derived from homeobox B7 (HOXB7)—a key controller of cell growth and oncogene activator—facilitates antigen presentation when pulsed onto dendritic cells obtained from human peripheral bl...
T81360	PSMα3 TFA
	PSMα3 TFA is a peptide utilized in directing dendritic cells (DCs) towards a tolerogenic state, pivotal for DC vaccination approaches. It intrudes and recalibrates human monocyte-derived DCs, disrupting maturation trigge...
T68182	3-Hydroxykynurenamine
	3-Hydroxykynurenamine, also known as 3-Hydroxy-L-kynurenamine or 3-HKA, is a biogenic amine produced via an alternative pathway of tryptophan metabolism. In vitro, 3-HKA has an anti-inflammatory profile by inhibiting the...
T64280	ODN 2216
	ODN 2216 is a TLR9 (toll-like receptor 9) ligand or agonist that induces the production of large amounts of IFN-α and IFN-β. ODN 2216 can induce IFN-α using pDC (plasma cell-like DC) and IL-12 (p40) using DC (dendritic c...
T79718	CaMKIIα-PHOTAC		CaMK
	CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα). This molecule facilitates the ubiquitination and subsequent proteasome-medi...		CaMK
T36984	Cyclic di-IMP (sodium salt)
	Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP . C-di-IMP has adjuvant properties when co-administered with ...
T83847	SP-A (196-215) (human) TFA	Surfactant Protein A,SPA4
	Surfactant protein A (SP-A) (196-215) is a synthetic peptide derived from the C-terminal carbohydrate recognition domain of human SP-A, specifically amino acids 196-215. This peptide suppresses LPS-induced TNF-α release ...
T37800	PF-04449613
	PF-04449613 is a phosphodiesterase 9A (PDE9A) inhibitor (IC50= 22 nM).1It is selective for PDE9A over PDE1C (IC50= >1,000 nM), as well as over a variety of other PDEs, inhibiting PDE2-8, -10, and -11 activity by less tha...
T83852	EGFRvIII Peptide TFA	PEGFRvIII (9-mer),Epidermal Growth Factor Receptor Variant III Peptide
	EGFRvIII peptide, a synthetic peptide mirroring the EGFRvIII fusion junction—a tumor-specific, perpetually active EGFR variant missing amino acids 6-273 of the wild-type—binds to HLA-A*0201-positive T2 cells under MHC cl...
T83825	Trofinetide acetate	NNZ-2566
	Trofinetide, derived from the neuroprotective tripeptide Gly-Pro-Glu (an N-terminal sequence of insulin-like growth factor-1, IGF-1), shows promise in various neuroprotective models. At a concentration of 10 nM, it mitig...

Compounds

ADH-503

T7776

Synonym: GB1275

Target: Complement System

GSK-J4

T3100

Synonym: GSK J4 HCl

Target: Apoptosis, Histone Demethylase

GSK-J4 Hydrochloride

T4383

Synonym: GSK J4 HCl,GSK J4 HCl (1373423-53-0 free base)

Target: Histone Demethylase

Jagged-1 （188-204）

TP1540

Synonym: Jagged-1 188-204

Target: Gamma-secretase

(Z)-Leukadherin-1

T13379

Synonym: ADH-503 free base

Target: Complement System

Apilimod

T2018

Synonym: STA 5326

Target: IL Receptor, PI3K, Interleukin

GGTI 2147 FA

T25450L

Synonym: GGTI2147 FA,GGTI-2147 FA,GGTI 2147 FA(191102-87-1 Free base)

KYL acetate(676657-00-4 free base)

TP1895L1

Synonym:

Target: Ephrin Receptor

Resiquimod

T6964

Synonym: R848,S28463

Target: HCV Protease, TLR

DG026

T27160

Synonym: DG 026,DG-026

Target:

BIT225

T26828

Synonym: BIT 225,BIT-225

Target:

N-Acetylpsychosine

T40452

Synonym: N-Acetylpsychosine,C2 Galactosylceramide (d18:1/2:0)

Synonym: C8 Dihydroceramide

Synonym: Incagn-02385

UDP-α-D-Glucose (sodium salt hydrate)

4-oxo Docosahexaenoic Acid

T36868

Synonym:

Target:

Jagged-1 (188-204) (TFA)

T76023

Synonym:

Target:

1-Arachidonoyl Lysophosphatidic Acid (ammonium salt)

Synonym: Gliotoxin-13C13

Synonym: CM 414,CM414

Synonym: Homeobox B7 (8-25)

3-Hydroxykynurenamine

Cyclic di-IMP (sodium salt)

T36984

Synonym:

Target:

SP-A (196-215) (human) TFA

T83847

Synonym: Surfactant Protein A,SPA4

Synonym: PEGFRvIII (9-mer),Epidermal Growth Factor Receptor Variant III Peptide

カタログ番号	製品名	別名	ターゲット
TN1445	Bisabolangelone		p38 MAPK , MAPK
	Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-κB signaling.		p38 MAPK , MAPK
T6S1027	Tussilagone		Others
	1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent for the prevention and treatment of human co...		Others
T5S2357	Acetylcorynoline	(+)-Corynoline Acetate,O-Acetylcorynoline	Antifungal
	1. Acetylcorynoline (O-Acetylcorynoline) has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. 3...		Antifungal
T4A2399	Cinobufotalin		IL Receptor , Akt , MRP , P-gp
	Cinobufotalin is a main cardiac toxin in toad, it is a novel anti-HCC agent, it induces growth inhibition and apoptosis in cultured HCC cells through ceramide production. Cinobufotalin is also an effective reversal agent...		IL Receptor , Akt , MRP , P-gp
T16733	Resolvin E1	RvE1	Others
	Resolvin E1 is an effective endogenous pro-resolving mediator of inflammation. Resolvin E1 has unique counterregulatory actions that inhibit PMN transendothelial migration. Resolvin E1 also acts as an effective inhibitor...		Others
TN1663	Ganoderic acid DM		PARP , Androgen Receptor , CDK
	Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1), this suppression leads to the inhibition of dendr...		PARP , Androgen Receptor , CDK
T38394	PSMα3
	PSMα3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies. It effectively penetrates and modulates human monocyte-derived DCs by modifying the maturation ...
T14063	7α,25-Dihydroxycholesterol	7α,25-OHC	EBI2/GPR183 , Endogenous Metabolite
			EBI2/GPR183 , Endogenous Metabolite

天然物製品

Bisabolangelone

TN1445

Synonym:

Target: p38 MAPK, MAPK

Synonym: (+)-Corynoline Acetate,O-Acetylcorynoline

Target: IL Receptor, Akt, MRP, P-gp

Target: PARP, Androgen Receptor, CDK

7α,25-Dihydroxycholesterol

T14063

Synonym: 7α,25-OHC

Target: EBI2/GPR183, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-01391	BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)	Mouse	Human Cells
	TNFSF13B/TNFSF20 belongs to the tumor necrosis factor family. It abundantly is expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bo...
TMPJ-00178	BAFF/TNFSF13B Protein, Human, Recombinant (His)	Human	Human Cells
	TNFSF13B/TNFSF20 belongs to the tumor necrosis factor family. It abundantly is expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bo...
TMPH-01984	CLECL1P Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	CLECL1P Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPJ-00177	BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated	Human	Human Cells
	B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytokine and serves as a ligand for receptors TNFRSF13B (TACI), T...
TMPY-05581	TIM-4/TIMD4 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	A type I transmembrane protein called TIM4 (T-cell immunoglobulin- and mucin-domain-containing molecule; also known as TIMD4), which belongs to the immunoglobulin superfamily and TIM family. TIM4 is involved in regulatin...
TMPJ-00607	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thy...
TMPY-06076	LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)	Human	HEK293
	LILRA2 (Leukocyte Immunoglobulin Like Receptor A2, also known as LIR7 and ILT1) is a Protein Coding gene. The encoded protein is an activating receptor that inhibits dendritic cell differentiation and antigen presentatio...
TMPY-04616	NKp30/NCR3 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Natural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp30, or CD337, is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and...
TMPY-01145	NKp30/NCR3 Protein, Human, Recombinant (His)	Human	HEK293
	Natural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp30, or CD337, is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and...
TMPY-02669	TIGIT Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a tr...
TMPY-04970	TIGIT Protein, Human, Recombinant (hFc)	Human	HEK293
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a tr...
TMPY-01068	CD70 Protein, Human, Recombinant (hFc)	Human	HEK293
	CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor, CD27, is important in priming, effector functions, diff...
TMPY-00118	MCP-1/CCL2 Protein, Human, Recombinant (His)	Human	Yeast
	Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit ...
TMPY-05345	TIGIT Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a tr...
TMPY-00772	DC-SIGN Protein, Human, Recombinant (hFc)	Human	HEK293
	Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3) grabbing nonintegrin (DC-SIGN), also known as CD209, is a type II transmembrane protein on DCs with a C-type lectin extracellular domain, is capable...
TMPY-01703	TREM-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-00432	TREM-2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-01148	TREM-2 Protein, Human, Recombinant (His)	Human	HEK293
	Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-06873	FLT3 Ligand Protein, Human, Recombinant	Human	E. coli
	FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of th...
TMPY-03215	FLT3 Ligand Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of th...
TMPJ-00064	OX40L/TNFSF4 Protein, Human, Recombinant (His)	Human	Human Cells
	Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein.OX40L is expressed on the surface of activated B cells, T cells, dendritic cells and endothelial cells. OX40L bin...
TMPY-03066	FLT3 Ligand Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of th...
TMPY-00480	NCAM1 Protein, Human, Recombinant (His)	Human	HEK293
	NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobuli...
TMPY-02971	CLEC10A Protein, Human, Recombinant (hFc)	Human	HEK293
	CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is ...
TMPY-05453	TSLP Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is ...
TMPY-02428	TSLP Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is ...
TMPY-05220	TSLP Protein, Human, Recombinant (R127A & R130S, His)	Human	HEK293
	Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is ...
TMPY-04650	IL-T3 Protein, Human, Recombinant (His)	Human	HEK293
	LILRB4 (Leukocyte Immunoglobulin Like Receptor B4) is a Protein Coding gene. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13....
TMPY-00033	4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc)	Human	HEK293
	4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as de...
TMPY-03142	IL-27 Protein, Human, Recombinant (His)	Human	CHO
	IL-27 protein is a member of the IL-6 superfamily, which is expressed on monocytes, endothelial cells, and dendritic cells. IL-27 protein is also referred to as the IL-12 p35-related protein, p28, is one subunit of a het...
TMPY-03153	IL-27 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	IL-27 protein is a member of the IL-6 superfamily, which is expressed on monocytes, endothelial cells, and dendritic cells. IL-27 protein is also referred to as the IL-12 p35-related protein, p28, is one subunit of a het...
TMPY-04614	IL-T3 Protein, Human, Recombinant (hFc)	Human	HEK293
	LILRB4 (Leukocyte Immunoglobulin Like Receptor B4) is a Protein Coding gene. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13....
TMPJ-00038	IL-7 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 a...
TMPY-03203	CD40 Protein, Rat, Recombinant (His)	Rat	HEK293
	CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPY-05510	BDNF Protein, Mouse, Recombinant (His)	Mouse	HEK293
	BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. B...
TMPY-05957	CD40 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPY-01181	CD40 Protein, Human, Recombinant (His)	Human	HEK293
	CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory...
TMPY-01963	IL-21 Protein, Human, Recombinant	Human	E. coli
	IL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellul...
TMPY-05274	IL-23R Protein, Human, Recombinant (His)	Human	HEK293
	IL23R, also known as the IL23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK, and dendritic cells. Isofo...
TMPY-03014	Osteoactivin/GPNMB Protein, Mouse, Recombinant (His)	Mouse	HEK293
	GPNMB belongs to the PMEL / NMB family, also known as Osteoactivin and Hematopoietic growth factor-inducible neurokinin 1 ( HGFIN ), is a transmembrane glycoprotein that is expressed in numerous cells, including osteocla...
TMPY-01829	CD83 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-04142	RANK/TNFRSF11A Protein, Human, Recombinant (hFc)	Human	HEK293
	TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-00695	I-309 Protein, Human, Recombinant (hFc)	Human	HEK293
	CCL1 or chemokine (C-C motif) ligand 1, also known as I-309 or TCA-3, is a member of the chemokine (C-C motif) ligand family. The C-C chemokines have two cysteines nearby the amino terminus. There have been at least 27 d...
TMPY-00674	B7-1 Protein, Human, Recombinant	Human	HEK293
	The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B c...
TMPY-02900	IL-17A Protein, Mouse, Recombinant	Mouse	E. coli
	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i...
TMPY-02698	CD14 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-02886	IL-17A Protein, Human, Recombinant	Human	E. coli
	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i...
TMPY-00854	IL-1 alpha/IL-1A Protein, Human, Recombinant	Human	HEK293
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPY-01738	IL-1 alpha/IL-1A Protein, Mouse, Recombinant	Mouse	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPY-06981	IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)	Human	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
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