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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T9522 | Rimtuzalcap | CAD-1883 | Potassium Channel |
Rimtuzalcap (CAD-1883) (CAD-1883), a pioneering selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels), is employed in the study of movement disorders such as spin... | |||
T0024 | Primidone | Primaclone,Mysoline,NCI-C56360 | GABA Receptor , Sodium Channel , GluR , AChR |
Primidone (NCI-C56360) is a potent anticonvulsant agent. It is a neuronal voltage-gated sodium channel blocker and has value in the study of epilepsy, essential tremor, and psychiatric disorders. | |||
T6595 | Moexipril hydrochloride | Moexipril HCl,RS-10085,SPM 925,CI-925 | Apoptosis , RAAS |
Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure. | |||
T28900 | T-2000 | DMMDPB | GABA Receptor |
T-2000 (DMMDPB) is a GABA receptor agonist that can be used to study myoclonus and essential tremor. | |||
T6390 | Anagrelide hydrochloride | BMY 26538-01,Anagrelide HCl,Agrylin,BL4162A | PDE |
Anagrelide hydrochloride (BL4162A) serves as a treatment for essential thrombocytosis. | |||
T17649 | Boc-GABA-OH | Others , PROTAC Linker | |
Boc-GABA-OH serves as a PROTAC linker essential for synthesizing UNC6852, an EED-targeted PROTAC[1]. | |||
T3460 | HhAntag | Hedgehog/Smoothened , Smo | |
HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway with the anti-tumor activity. | |||
T2621 | Rostafuroxin | PST 2238 | ATPase , RSV |
Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension. | |||
T1482 | Ciclopirox | HOE296b | ATPase , Ferroptosis , Antibacterial , Autophagy , Antifungal |
Ciclopirox (HOE296b) exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. Ciclopirox is a synthetic, broad-spect... | |||
T8037 | H-Phe-Phe-OH | Endogenous Metabolite | |
H-Phe-Phe-OH is a dipeptide consisting of two phenylalanine (an essential amino acid and precursor to tyrosine) units linked together. | |||
T5885 | N-Acetyl-D-galactosamine | GalNAc | Others |
N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans. | |||
T9372 | D-Histidine | Mitochondrial Metabolism | |
D-Histidine is an enantiomer of L-histidine. L-Histidine is an inhibitor of mitochondrial glutamine transport and also an essential amino acid for infants. | |||
T17753 | DBCO-mPEG (MW 5kDa) | Others | |
DBCO-mPEG (MW 5kDa) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syst... | |||
T17441 | Amino-PEG9-alcohol | Others , PROTAC Linker | |
Amino-PEG9-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syste... | |||
T6219 | Azilsartan Medoxomil | TAK-491 | RAAS |
Azilsartan Medoxomil (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension. | |||
T17014 | TCO-NHS ester | Others , PROTAC Linker | |
TCO-NHS ester is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sy... | |||
T17978 | Fmoc-PEG12-NHS ester | Others , PROTAC Linker | |
Fmoc-PEG12-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys... | |||
T17719 | Cbz-NH-PEG12-C2-acid | Others , PROTAC Linker | |
Cbz-NH-PEG12-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys... | |||
T0412 | Idebenone | CV-2619 | Apoptosis , Antioxidant , Mitochondrial Metabolism |
Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC). | |||
T18886 | 3,6-Dichlorotrimellitic anhydride | Others | |
3,6-Dichlorotrimellitic anhydride serves as the essential precursor in the synthesis of various dichlorinated fluoresceins and rhodamines. | |||
T10727 | Cdc7-IN-5 | CDK | |
Cdc7-IN-5 is a potent inhibitor of Cdc7 kinase. Cdc7, a serine-threonine protein kinase enzyme, is essential for the initiation of DNA replication in the cell cycle. | |||
T8368 | Geranylacetone(Z/E) | Dihydropseudoionone | Others |
Geranylacetone(Z/E) (Dihydropseudoionone) is a naturally occurring compound found in the essential oils of many plants, including rosemary, lavender and jasmine. It has antioxidant, anti-inflammatory and anti-microbial p... | |||
T2213 | Terconazole | Gyno-Terazol,Terazol 3,Terazol 7,Triaconazole,R42470 | Antifection , Antifungal |
Terconazole (Terazol 7) is a synthetic triazole derivative structurally related to fluconazole, antifungal Terconazole seems to disrupt cell wall synthesis by inhibiting biosynthesis of ergosterol or other sterols, damag... | |||
T3602 | D-Pantothenic acid sodium | D-Pantothenate Sodium,D-Pantothenic acid sodium salt,Sodium pantothenate,vitamin B5 sodium | Apoptosis , Others |
D-Pantothenic acid sodium (vitamin B5 sodium) , the sodium salt of D-pantothenate, is a derivative of vitamin B5 which is an an essential nutrient and plays important roles in the oxidation of fats and carbohydrates and ... | |||
T27119L | (Rac)-Daglutril | SLV 306 acetic acid,2-((3S)-3-(1-(2-(ethoxycarbonyl)-4-phenylbutyl)cyclopentane-1-carboxamido)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid | Others |
(Rac)-Daglutril (SLV 306 acetic acid) is the racemate form of Daglutril. Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential ... | |||
T4647 | M2I-1 | M2I 1 | Others |
M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. It can disturbs conformational dynamics of Mad2 cri... | |||
TP1782L | CEF3 acetate(199727-62-3 free base) | Influenza Virus | |
CEF3 acetate corresponds to aa 13-21 of the influenza A virus M1 protein. The matrix (M1) protein of influenza A virus is a multifunctional protein that plays essential structural and functional roles in the virus life c... | |||
T1497 | Liranaftate | Piritetrate,M-732 | Antifungal |
Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is ... | |||
T3489 | Dasabuvir | ABT-333 | HCV Protease |
Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase, with potential activity against HCV. Upon administration and after intra... | |||
T3336 | Rg3039 | PF-06687859 | Others |
Rg3039 (PF-06687859) is a potent DcpS inhibitor. DcpS is a therapeutic target for spinal muscular atrophy. Spinal muscular atrophy (SMA) is caused by deletion or mutation of both copies of the SMN1 gene which produces an... | |||
T4054 | Dantrolene sodium hemiheptahydrate | Dantrolene sodium hydrate,Dantrolene sodium salt,Dantrium,Sodium dantrolene | Calcium Channel , Autophagy |
Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration. Ryanodine receptors mediate the release of calcium from t... | |||
T6543 | Indoximod | NLG-8189,Indoximod (NLG-8189),1-Methyl-D-tryptophan | Indoleamine 2,3-Dioxygenase (IDO) |
Indoximod (Indoximod (NLG-8189)) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan... | |||
T60554 | Schnurri-3 inhibitor-1 | Others | |
Schnurri-3 inhibitor-1, a potent inhibitor of schnurri-3, is an essential regulator of bone formation in adults that can be used in osteoporosis research. Schnurri-3 inhibitor-1 can inhibit Shn3 with EF1alpha promoter in... | |||
T3069 | AZD-1480 | JAK | |
AZD1480 is a novel ATP-competitive JAK2 inhibitor (IC50: 0.26 nM), selectivity act against Tyk2 and JAK3, and to a smaller extent against JAK1. AZD1480 has been used in trials studying the treatment of Solid Malignancies... | |||
T9492 | 3-METHOXY-DL-TYROSINE | Others | |
3-METHOXY-DL-TYROSINE is a naturally occurring, non-essential amino acid found in the human body and many other organisms. It is a precursor to the neurotransmitter dopamine and is involved in the regulation of dopamine ... | |||
T38905 | FATP1-IN-1 | FATP1-IN-1 | Others |
FATP1-IN-1 is a potent inhibitor of fatty acid transport protein 1 (FATP1). It effectively inhibits the activity of recombinant human or mouse acyl-CoA synthetase, which is essential for the function of FATP1. The inhibi... | |||
T1290 | Oxiconazole nitrate | Ro 13-8996 | Others , Antibiotic , Antifection , Antifungal |
Oxiconazole nitrate (Ro 13-8996) is the nitrate salt form of oxiconazole, a broad spectrum imidazole derivative with antifungal activity. Although the exact mechanism of action has yet to be fully elucidated, oxiconazole... | |||
T1187 | Bifonazole | Bay H-4502 | P450 , Antibiotic , Antifungal |
Bifonazole (Bay H-4502) acts to destabilize the fungal cytochrome p450 51 enzyme (also known as Lanosterol 14-alpha-demethylase). It works by inhibiting the production of a substance called ergosterol, which is an essent... | |||
T40376 | L-Phenylalanine-15N | (S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N | Calcium Channel |
L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) is the 15N-labeled L-Phenylalanine. L-Phenylalanine is an essential amino acid isolated from Escherichia coli . L-Phenylalanine is a α2δ subunit of voltage-dep... | |||
T3934 | Isavuconazonium sulfate | Antifungal | |
Isavuconazonium sulfate is hydrolyzed by plasma esterases to yield the active moiety isavuconazole. Isavuconazole binds to and inhibits the fungal cytochrome P450 family enzyme lanosterol 14-alpha-demethylase (CYP51), wh... | |||
T4570 | Pipobroman | Vercyte,A-8103,Amedel | Others , DNA Alkylator/Crosslinker |
Pipobroman (Vercyte) is an anti-cancer drug that probably acts as an alkylating agent. Pipobroman has well documented clinical activity in polycythemia vera (PV) and essential thrombocythemia (ET). Pipobroman allows, wit... | |||
T3226 | Paritaprevir | ABT-450,Veruprevir | HCV Protease |
Paritaprevir (ABT-450) is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein 3 and 4A (NS3/NS4A), with potential activity again... | |||
T31711L | Ethyl L-leucinate | Leucine ethyl ester | |
Ethyl L-leucinate is a essential amino acid. | |||
T1547L | Cysteine monohydrate | Cysteine hydrate,L-Cysteine, monohydrate | |
Cysteine monohydrate is a semi-essential proteinogenic amino acid. | |||
T32654 | Leptospermone | ||
Leptospermone is an essential oil from Leptospermum scoparium (manuka oil). | |||
T32900 | Saccharopine | L-Saccharopine,accharopin | |
L-Saccharopine is a product of the breakdown of essential amino acid Lysine. | |||
T32220 | Isomyristicin | trans-Isomyristicin | |
Isomyristicin is a natural essential oil which shows activity against Trichuris muris. | |||
T34070 | Piperitenone oxide | Rotundifolone,Lippione,cis-Piperitenone epoxide,Piperitenone oxide, (+-)- | |
Piperitenone oxide is a major chemical constituent of the carvone pathway MS essential oil. | |||
T20167 | Cilazapril | Ro-34-2848,Ro 34-2848,Cilazapril (anhydrous),Ro34-2848 | |
Cilazapril is an angiotensin-converting enzyme inhibitor. It has been researched for mild to moderate essential hypertension. | |||
T28324 | PD 125967 | PD125967,PD-125967 | |
PD 125967 is a renin inhibitor, which represents a group of pharmaceutical drugs used primarily to treat essential hypertension. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T40797 | Essential oils, Melaleuca alternifolia | ||
Melaleuca alternifolia essential oil, derived from the leaves of Melaleuca alternifolia, exhibits bactericidal and anti-inflammatory properties. | |||
T7930 | Linalyl Acetate | Others | |
Linalyl Acetate is a natural product | |||
T5692 | Pyrroloquinoline quinone | Others , Endogenous Metabolite | |
Pyrroloquinoline quinone (PQQ), as a well-known redox enzyme cofactor, PQQ can protect NS/PCs against glutamate toxicity associated with ROS-mediated mitochondrial pathway, | |||
T10857 | Coenzyme A | Endogenous Metabolite | |
Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine. | |||
T3S2381 | Perillene | 3-Isohexenylfuran,Perillen | Others , Antibacterial |
Perillene (3-Isohexenylfuran) is an actiive constituent in the drug which promotes enterocinesia. Perillen demonstrates strong resistance activity against staphylococcus aureus and E.coli. | |||
T5667 | Octyl acetate | Acetic acid octyl ester | Others |
Octyl acetate (Acetic acid octyl ester) is the acetate ester of octan-1-ol. It has a role as a plant metabolite.Acetic acid octyl ester is present in citrus peel oils. | |||
T8392 | L(+)-Asparagine monohydrate | Endogenous Metabolite | |
L(+)-Asparagine monohydrate is a non-essential amino acid, participate in neurological and metabolic regulation of tissue cell function. | |||
T8242 | Sabinene | Others | |
Sabinene is a natural product that has antifungal and anti-inflammatory properties | |||
T3314 | Perillyl alcohol | Isocarveol,Perilla alcohol | Apoptosis , Endogenous Metabolite |
Perillyl Alcohol is a naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol (Isocarveol) inhibits farnesyl transferase and geranylgeranyl transferase, thereby preventing post-... | |||
T8283 | (+)-Bornyl Acetate | Bornyl acetate | Others |
(+)-Bornyl Acetate has a stronger inhibitory effect on root growth of Arabidopsis seedlings. | |||
TJO2742 | DL-Methionine | methionine,Acimetion,Racemethionine | Parasite |
DL-Methionine (Acimetion) is an amino acid. Amino acids are the building blocks that our bodies use to make proteins. DL-Methionine is found in meat, fish, and dairy products. It plays an important role in the many funct... | |||
TN5283 | L-Cysteine hydrochloride hydrate | L-Cysteine hydrochloride monohydrate | Others , Endogenous Metabolite |
L-Cysteine hydrochloride hydrate (L-Cysteine hydrochloride monohydrate) is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), taurine and gl... | |||
T7909 | α-Terpinene | Others , Parasite , Antifungal | |
α-Terpinene is a terpenoid,has acaricidal, antiprotozoal, and antioxidant properties | |||
T8256 | Piperitone | Others | |
piperitone is a natural compound from Piper nigrum L | |||
T5693 | Pyrroloquinoline quinone disodium salt | Methoxatin disodium salt | Others , Endogenous Metabolite |
Pyrroloquinoline quinone disodium salt (Methoxatin disodium salt), an aromatic tricyclic o-quinone, is a redox cofactor for bacterial dehydrogenases. It is an efficient electron transfer catalyst from a number of organic... | |||
T4P2931 | Linoleic acid | 9,12-octadecadienoic acid,acidelinoleique,9,12-Linoleic acid | Others , Endogenous Metabolite |
Linoleic acid (9,12-octadecadienoic acid) is an essential fatty acid. Prostaglandin precursor. | |||
T5621 | β-Phellandrene | beta-Phellandrene,p-mentha-1(7),2-diene | Others |
β-Phellandrene (p-mentha-1(7),2-diene) is found in allspice. beta-Phellandrene is widely distributed in essential oils | |||
T1116 | Biotin | Vitamin B7,D-Biotin,Vitamin H | |
Biotin (Vitamin H) is a water-soluble B-vitamin and is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. | |||
T9112 | (-)-Perillaldehyde | AhR , ROS , Nrf2 | |
(-)-Perillaldehyde shows antibacterial activity. | |||
T3P2904 | α-Linolenic acid | Alpha-Linolenic Acid,Linolenic acid | Akt , PI3K |
α-Linolenic acid (Alpha-Linolenic Acid) is an essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been reported to inhibit the synthesis of prostagland... | |||
T3377 | L-Phenylalanine | (S)-2-Amino-3-phenylpropionic acid,phenylalanine,3-Phenyl-L-alanine | Calcium Channel , Endogenous Metabolite , iGluR |
L-Phenylalanine (3-Phenyl-L-alanine) is an essential amino acid and the precursor of the amino acid tyrosine, acts as an antagonist at α2δ calcium channels. | |||
T35702 | 2-Heptanol | s-Heptyl alcohol,Heptan-2-ol,Heptanol-2 | Antioxidant , Antibacterial |
2-Heptanol (s-Heptyl alcohol) is a chemical compound found in the essential oil extracted from the rhizome of Curcuma angustifolia and Curcuma zedoaria. The rhizome essential oil demonstrates noteworthy antimicrobial and... | |||
T35704 | 2-Methoxybenzaldehyde | o-Anisaldehyde | Antibacterial , Antifungal |
2-Methoxybenzaldehyde (o-Anisaldehyde) (o-Anisaldehyde), obtained from cinnamon essential oil (CEO), exhibits antibacterial and antifungal properties [1]. | |||
T13923 | Thiamine nitrate | Vitamin B1 nitrate | Others |
Thiamine nitrate (Vitamin B1 nitrate) is an essential vitamin, and can enhance normal neuronal actives. | |||
T8079 | α-Terpinyl acetate | Terpinyl Acetate | Others , P450 |
α-Terpinyl acetate is a natural compound found in several essential oils, is a flavouring agent. | |||
T5615 | Benzyl acetate | Phenylmethyl acetate,Benzyl ethanoate | Others |
Benzyl acetate is a constituent of Jasmin and of the essential oils of ylang-ylang and neroli. | |||
T2S0493 | Isoeugenol | 4-Propenylguaiacol,2-Methoxy-4-propenylphenol | Antibacterial |
Isoeugenol (4-Propenylguaiacol), an essential oil constituent of nutmeg, clove, and cinnamon, shows antimicrobial activity. | |||
T8097 | Methyl 3-aminopropanoate hydrochloride | β-Alanine methyl ester hydrochloride | Others |
Methyl 3-aminopropanoate hydrochloride (β-Alanine methyl ester hydrochloride) is the ethyl ester of the non-essential amino acid β-alanine. | |||
T5369 | Docosahexaenoic Acid | Cervonic acid,DHA | Others , Endogenous Metabolite |
Docosahexaenoic Acid (DHA) is an essential fatty acid and an omega-3 fatty acid abundant in brain and retina. | |||
T4844 | L-Methionine | L(-)-Methionin,L-Methionin | Endogenous Metabolite |
L-Methionine (L-Methionin) is the L-isomer of Methionine. Methionine is an essential amino acid for human development and acts as a hepatoprotectant. | |||
T2O2776 | L-Valine | Others , Endogenous Metabolite | |
A branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway. | |||
T4921 | Oxoadipic acid | 2-Oxoadipic acid | Endogenous Metabolite |
Oxoadipic acid (2-Oxoadipic acid) is a key metabolite of the essential amino acids tryptophan and lysine.Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research on mitochondrial metab... | |||
T0326L | L-Glutamine | L-Glutamic acid 5-amide | Ferroptosis , Endogenous Metabolite , GluR |
L-Glutamine (L-Glutamic acid 5-amide) , a non-essential amino acid, is synthesized from glutamic acid and ammonia. | |||
T2852 | Citropten | Limettin,Citroptene,Limetin,5, 7-Dimethoxycoumarin,5,7-Dimethoxycoumarin | Others |
Citropten (Limetin) is a natural organic compound and is found in the essential oils of citrus such as lime, lemon, and bergamot. | |||
T8363 | DL-Serine | PKM | |
DL-Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2. | |||
T17056 | Tetrahydrobiopterin | Sapropterin,BH4,(Rac)-Sapropterin | NOS , Endogenous Metabolite |
Tetrahydrobiopterin (BH4) is a cofactor for aromatic amino acid hydroxylases and an essential cofactor for nitric oxide synthase (NOS), which is used in the study of endothelial dysfunction such as hypertension, hypercho... | |||
T5548 | Verbenone | 2-Pinen-4-one,(-)-Verbenone | Others |
(-)-Verbenone ((-)-Verbenone) is an important component of the essential oil from rosemary. It is also an insect pheromone with a spicy odor and camphoraceous fragrance. | |||
T3007 | Spermine | Gerontine,Musculamine,4,9-Diaza-1,12-dodecanediamine,NSC 268508,Neuridine | Influenza Virus , Endogenous Metabolite |
Spermine (Neuridine) is a biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. | |||
T8071 | L-Lysine hydrochloride | Lysine hydrochloride | Virus Protease |
L-Lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, reducing diabetes-related illnesses, increasing calcium absorption and improving gut health. | |||
TN3604 | Carveol | (-)-Carveol, mixture of isomers | Endogenous Metabolite |
(-)-Carveol ((-)-Carveol, mixture of isomers), mixture of isomers is a monocyclic monoterpenic alcohol, present in essential oils of plant species such as Cymbopogon giganteus, Illicium pachyphyllum and in spices such as... | |||
T5649 | Estragole | Methyl chavicol,p-Allylanisole,4-Allylanisole | Others |
Estragole (4-Allylanisole) is found in allspice,and is a constituent of many essential oils. Estragole is a flavouring agent. | |||
T6523 | Guanosine | DL-Guanosine,Vernine,Guanozin | Endogenous Metabolite , HSV |
Guanosine (DL-Guanosine) is a purine nucleoside formed from a beta-N9-glycosidic bond between guanine and a ribose ring and is essential for metabolism. | |||
T22235 | Lipoic acid | R-(+)-Thioctic acid,(R)-(+)-1,2-Dithiolane-3-pentanoic acid,(R)-(+)-α-Lipoic acid | Reactive Oxygen Species , Mitochondrial Metabolism , Endogenous Metabolite |
Lipoic acid (R-(+)-Thioctic acid) is an organosulfur compound derived from octanoic acid. It is made in animals normally, and is essential for aerobic metabolism. | |||
T13693 | Fibrin | Others | |
Fibrin, the primary constituent of blood clots, is an insoluble protein essential for coagulation. Isolated from bovine blood, this protein is notably synthesized in response to bleeding. | |||
T0493 | L-Tyrosine | Tyrosine,P-Tyrosine,L-p-Tyrosine,(S)-Tyrosine | Amino Acids and Derivatives , Endogenous Metabolite |
L-Tyrosine ((S)-Tyrosine) is a naturally occurring tyrosine and is synthesized in vivo from L-phenylalanine, considered a non-essential amino acid. L-Tyrosine(L-p-Tyrosine) is the levorotatory isomer of the aromatic amin... | |||
TN1373 | α-Humulene | Alpha-caryophyllene | TNF , NOS , COX |
α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory effects, probably by interfering with TNFalpha production an... | |||
T0063 | L-Isoleucine | isoleucine,Ile | Amino Acids and Derivatives , Endogenous Metabolite |
L-Isoleucine (Ile) is an essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of LEUCINE. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels. | |||
T7132 | (Rac)-Brassinazole | BRASSINAZOLE | P450 |
(Rac)-Brassinazole are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole is a triazole-type brassinosteroid biosynth... | |||
T8141 | L-Cysteine hydrochloride | L-Cysteine HCl | Others , Endogenous Metabolite |
L-Cysteine hydrochloride (L-Cysteine HCl) is a conditionally essential amino acid,L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents and humans | |||
T6624 | Oxytetracycline Dihydrate | Terramycin Dihydrate | Others , Endogenous Metabolite , Antibacterial , Antibiotic , HSV |
Oxytetracycline Dihydrate (Terramycin Dihydrate) is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins. | |||
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カタログ番号 | 製品名 | Species | Expression System |
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TMPH-00010 | MMP-14 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tiss... | |||
TMPY-00005 | FGF-8a Protein, Human, Recombinant | Human | E. coli |
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment... | |||
TMPY-06986 | FGF-8b Protein, Human, Recombinant | Human | E. coli |
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment... | |||
TMPJ-00412 | VEGFR1/FLT-1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ... | |||
TMPJ-01464 | IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F) | Human | HEK293 Cells |
Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system,belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or m... | |||
TMPJ-00562 | PDGF-BB Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P... | |||
TMPY-00365 | GALNT7 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
GalNAc-transferase-7 (GALNT7) is essential for the regulation of cell proliferation and has been implicated in tumorigenesis. Colorectal cancer (CRC) arises in a multistep molecular network process, which is from either ... | |||
TMPJ-00166 | SCF Protein, Mouse, Recombinant | Mouse | E. coli |
Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gameto... | |||
TMPY-04483 | IRAK4 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4... | |||
TMPY-02575 | PPAR gamma/PPARG Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling even... | |||
TMPY-04125 | PTP1B Protein, Human, Recombinant (His) | Human | E. coli |
PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c... | |||
TMPY-00817 | Granzyme B/GZMB Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ... | |||
TMPY-02929 | ENTPD2 Protein, Human, Recombinant (aa 29-460, His) | Human | Baculovirus Insect Cells |
NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; ... | |||
TMPJ-00994 | LTBR Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including ce... | |||
TMPY-04830 | GAS6 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ... | |||
TMPY-02869 | MMP-12 Protein, Human, Recombinant (catalytic domain) | Human | E. coli |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ... | |||
TMPY-02219 | Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His) | H1N1 | E. coli |
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the N... | |||
TMPY-01101 | Coagulation factor X/F10 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the... | |||
TMPH-01215 | DHH Protein, Human, Recombinant (GST & His & Myc) | Human | E. coli |
Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development. | |||
TMPH-03719 | YopH Protein, Yersinia enterocolitica, Recombinant (His & Myc) | Yersinia enterocolitica | E. coli |
Essential virulence determinant. This protein is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to... | |||
TMPH-01536 | ITGB4 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG... | |||
TMPH-02397 | MIP Protein, Legionella longbeachae, Recombinant (His & Myc) | Legionella longbeachae | E. coli |
Essential virulence factor associated with macrophage infectivity. Exhibits PPIase activity. | |||
TMPH-00772 | Leghemoglobin C2 Protein, Glycine max, Recombinant (His) | Glycine max | E. coli |
Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation. | |||
TMPH-03717 | YopE Protein, Yersinia enterocolitica, Recombinant (His) | Yersinia enterocolitica | E. coli |
Essential virulence determinant; cytotoxic effector, involved in resistance to phagocytosis. | |||
TMPH-02128 | SMOC1 Protein, Human, Recombinant (GST & His) | Human | E. coli |
Plays essential roles in both eye and limb development. Probable regulator of osteoblast differentiation. | |||
TMPH-00608 | Dihydrofolate reductase Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
TMPJ-00504 | Serpin A8 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hyperten... | |||
TMPH-02826 | PEX5 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. | |||
TMPH-02383 | Lake Victoria marburgvirus (MARV) (strain Musoke-80) VP35 Protein (His) | MARV | E. coli |
Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling. | |||
TMPY-05001 | MPZL3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MPZL3 (Myelin Protein Zero Like 3) is a Protein Coding gene. The encoded protein belongs to the myelin P0 protein family. MPZL3 is broadly expressed in skin, esophagus, and other tissues. MPZL3 was essential for normal d... | |||
TMPH-03002 | FtsQ Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) | Mycobacterium tuberculosis | E. coli |
Essential cell division protein. FtsQ Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.2 kDa and the... | |||
TMPK-00972 | PK-1/PROK1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
PK-1 (Ac10) is a baculovirus-encoded serine/threonine kinase,a pk-1 knockout AcMNPV failed to produce infectious progeny, while the pk-1 repair virus could rescue this defect.the kinase activity of PK-1 is essential in r... | |||
TMPK-00509 | E-Cadherin/Cadherin-1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
E-cadherin is the core component of epithelial adherens junctions, essential for tissue development, differentiation, and maintenance. It is also fundamental for tissue barrier formation, a critical function of epithelia... | |||
TMPK-00323 | M-CSF/CSF1 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of... | |||
TMPH-01790 | NUP210 Protein, Human, Recombinant (His) | Human | E. coli |
Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. NUP210 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The ... | |||
TMPH-00252 | Bovine coronavirus (strain Mebus) Protein I (His) | BCoV | E. coli |
Structural protein that is not essential for the viral replication either in tissue culture or in its natural host. Bovine coronavirus (strain Mebus) Protein I (His) is expressed in E. coli expression system with C-6xHis... | |||
TMPH-02840 | PLOD2 Protein, Mouse, Recombinant (E. coli, His & Myc) | Mouse | E. coli |
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-link... | |||
TMPY-00610 | RAB2 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
RAB2A, a protein essential for ER-to-Golgi transport, is critical in promoting proteolytic activity and 3D invasiveness of breast cancer (BC) cell lines.RAB2A is amplified and elevated in human BC and is a powerful and i... | |||
TMPK-00324 | M-CSF/CSF1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of... | |||
TMPH-03134 | Leghemoglobin Lb120-8 Protein, Pisum sativum, Recombinant (His) | Pisum sativum | E. coli |
Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation. Leghemoglobin Lb120-8 Protein, Pisum sativum, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The p... | |||
TMPK-01251 | L1R Protein, Monkeypox virus, Recombinant (His) | Monkeypox virus | E. coli |
L1R, a myristylated late gene product of vaccinia virus, is essential for formation of infectious intracellular mature virions (IMV). In its absence, only viral particles arrested at an immature stage are detected and no... | |||
TMPH-01224 | Dihydrofolate reductase Protein, Human, Recombinant (His) | Human | E. coli |
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds... | |||
TMPH-03092 | Leghemoglobin A Protein, Phaseolus vulgaris, Recombinant (His & Myc) | Phaseolus vulgaris | E. coli |
Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation. Leghemoglobin A Protein, Phaseolus vulgaris, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and ... | |||
TMPH-00032 | ASFV (strain Ba71V) p17 Protein (His) | ASFV | E. coli |
Essential for the correct processing of both structural polyproteins and for the maturation of viral precursor membranes at the viral factories. ASFV (strain Ba71V) p17 Protein (His) is expressed in E. coli expression sy... | |||
TMPH-00256 | Bovine coronavirus (strain LY-138) Protein I (His) | BCoV | E. coli |
Structural protein that is not essential for the viral replication either in tissue culture or in its natural host. Bovine coronavirus (strain LY-138) Protein I (His) is expressed in E. coli expression system with C-6xHi... | |||
TMPY-03225 | VSIG8 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
V-set and immunoglobulin domain containing 8 (VSIG8) is essential in hair cycle, oral mucosa, and the nail matrix. Moreover, VSIG8 also has an important role in proper epithelial differentiation and function in the upper... | |||
TMPH-00757 | Reticuline oxidase Protein, Eschscholzia californica, Recombinant (His) | Eschscholzia californica | E. coli |
Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbo... | |||
TMPH-00253 | Bovine coronavirus (strain 98TXSF-110-LUN) Protein I (His) | BCoV | E. coli |
Structural protein that is not essential for the viral replication either in tissue culture or in its natural host. Bovine coronavirus (strain 98TXSF-110-LUN) Protein I (His) is expressed in E. coli expression system wit... | |||
TMPH-00254 | Bovine coronavirus (strain 98TXSF-110-ENT) Protein I (His) | BCoV | E. coli |
Structural protein that is not essential for the viral replication either in tissue culture or in its natural host. Bovine coronavirus (strain 98TXSF-110-ENT) Protein I (His) is expressed in E. coli expression system wit... | |||
TMPH-02401 | RplL Protein, Legionella pneumophila, Recombinant (His & Myc) | Legionella pneumophila | E. coli |
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation. rplL Protein, Legionella pneumophila, Recombinant (His & Myc) is express... | |||
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カタログ番号 | 製品名 | ||
---|---|---|---|
L3100 | Hematopoietic Toxicity Compound Library | 101 compounds | |
A unique collection of 101 compounds with defined hematopoietic toxicity for high throughput and high content drug screening; | |||
L8710 | Cuproptosis Compound Library | 400 compounds | |
TargetMol’s Cuproptosis Compound Library is a collection of 400 compounds related to copper-dependent death that can be used to study its mechanism and related diseases. | |||
L2500 | Human Endogenous Metabolite Library | 499 compounds | |
A collection of 499 selected human endogenous metabolites for high throughput and high content screening. | |||
L2600 | Neuronal Signaling Compound Library | 2540 compounds | |
A unique collection of 2540 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L1110 | Microtubule-Targeted Compound Library | 142 compounds | |
A unique collection of 142 microtubule-targeted compounds can be used in HTS and HCS; | |||
L2130 | Anti-Cancer Metabolism Compound Library | 1268 compounds | |
A unique collection of 1268 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCS); | |||
L2510 | Lipid Metabolism Compound Library | 492 compounds | |
A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS). | |||
L1310 | Cytoskeletal Signaling Pathway Compound Library | 759 compounds | |
A unique collection of 759 cytoskeleton-related compounds, can be used for HTS and HCS; | |||
L2630 | Neuronal Differentiation Compound Library | 672 compounds | |
L8500 | HIF-1 Signaling Pathway Compound Library | 1336 compounds | |
A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies; | |||
L2550 | Glutamine Metabolism Compound Library | 565 compounds | |
A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ... | |||
L6400 | Marine Natural Product Library | 144 compounds | |
A unique collection of 144 marine natural products for high throughput screening (HTS) and high content screening (HCS); |