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天然化合物

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カタログ番号	製品名	別名	ターゲット
T2701	GSK1292263		GPR
	GSK1292263 is a GPR119 agonist and has been investigated for the treatment of DIABETES MELLITUS, TYPE 2.		GPR
T6237	Trelagliptin	SYR-472	Proteasome , DPP-4
	Trelagliptin (SYR-472) is a highly specific and long-acting DPP-4 inhibitor.		Proteasome , DPP-4
T15432	GSK256073		GPR , Others
	GSK256073 is an orally active GPR109A agonist. GSK256073 also is a long-lasting and non-flushing HCA2 (hydroxy-carboxylic acid receptor 2) full agonist (pEC50: 7.5). GSK256073 acutely improves glucose homeostasis via inh...		GPR , Others
T9022	AZD9977	AZD 9977	Glucocorticoid Receptor
	AZD9977 is a novel, selective modulator of mineralocorticoid receptor .		Glucocorticoid Receptor
T2711	Chembridge-5861528	TCS 5861528	TRP/TRPV Channel
	Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM, respectively.		TRP/TRPV Channel
T23521	VULM 1457		Acyltransferase
	VULM 1457 is a potent ACAT inhibitor. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM1457 significantly reduces production and secretion of...		Acyltransferase
T1088	Repaglinide	AG-EE 388 ZW,AG-EE 623ZW	Potassium Channel , PPAR
	Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repaglinide has been linked to rare instances of clinically appare...		Potassium Channel , PPAR
T8780	AMG131	INT-131,AMG-131,CHS 131	PPAR
	AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin depende...		PPAR
T0334	Rosiglitazone	BRL49653	Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
	Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity. Rosiglitazone is also a hypoglycemic agent and a thiazolidinedione insulin sensitizer.		Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
T7369L	Gemigliptin Tartrate(911637-19-9 free base)	LC15-0444 tartrate	Proteasome , DPP-4
	Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibit...		Proteasome , DPP-4
T1603	Glipizide	CP 28720,K 4024	Potassium Channel , PPAR , ABC
	Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.		Potassium Channel , PPAR , ABC
T6646	Rosiglitazone hydrochloride	BRL-49653 HCl,Rosiglitazone HCl	Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
	Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.		Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
T2296	Trelagliptin succinate	SYR-472 succinate,SYR472	Proteasome , DPP-4
	Trelagliptin succinate (SYR-472 succinate) is a long-acting inhibitor of dipeptidyl peptidase-4 (DPP-4), being developed for the treatment of type 2 diabetes (T2D).		Proteasome , DPP-4
T1637	Deferoxamine Mesylate	desferrioxamine B,Desferrioxamine B mesylate,DFO,DFOM	Mitophagy , Beta Amyloid , Others , Ferroptosis , HIF/HIF Prolyl-Hydroxylase , Autophagy
	Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulation. Deferoxamine Mesylate up-regulates HIF-1α levels and i...
T31992	Granotapide		CETP
	Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic syndrome, obesity, diabetes mellitus, prediabetes mellitus, an...		CETP
T3104	Globalagliatin	LY2608204	Glucokinase
	Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2.		Glucokinase
T2316	Omarigliptin	MK-3102	Proteasome , DPP-4
	Omarigliptin (MK-3102) has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal Insufficiency.		Proteasome , DPP-4
T71394	BMS-823778
	BMS-823778 is an orally available potent and selective inhibitor of 11-β-hydroxysteroid-dehydrogenase 1 (11βHSD-1). BMS-823778 is a potential therapeutic agent for type 2 diabetes mellitus (T2DM).
T0490	Chlorpropamide	Diabinese	ATPase , ABC
	Chlorpropamide (Diabinese) is a sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification.		ATPase , ABC
T6961	PX-478	PX-478 2HCl	HIF/HIF Prolyl-Hydroxylase , HIF , Autophagy
	PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability. PX-478 has antitumor activity and also protects pancreatic β-cell function in diabetes mellitus and is used in type 2 di...		HIF/HIF Prolyl-Hydroxylase , HIF , Autophagy
T14130	Adomeglivant	LY2409021	Glucagon Receptor
	Adomeglivant (LY2409021) is a potent and selective glucagon receptor antagonist. Which is used in clinical trial for type 2 diabetes mellitus.		Glucagon Receptor
TP1796	Albiglutide TFA (782500-75-8 free base)	Albiglutide TFA	Glucagon Receptor
	Albiglutide TFA (782500-75-8 free base) (Albiglutide TFA) is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM).		Glucagon Receptor
TP1469	Lixisenatide acetate (320367-13-3 free base)	Lixisenatide acetate	Glucagon Receptor
	Lixisenatide acetate is a receptor agonist similar to glucagon-like peptide-1 (glp-1) for the treatment of type 2 diabetes mellitus (T2DM).		Glucagon Receptor
T77784	WAY-297848		Glucokinase
	WAY-297848 is a novel glucokinase activator for the prevention or treatment of hyperglycemia, diabetes mellitus, obesity, dyslipidemia, and metabolic syndrome.		Glucokinase
T15244	Ertugliflozin L-pyroglutamic acid	PF-04971729 L-pyroglutamic acid	Others , SGLT
	Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM. Ertugliflozin L-pyroglutamic acid can be used for studies about the treatmen...		Others , SGLT
T78223	γ-Glu-Tyr	gamma-Glutamyltyrosine,gamma-GLU-TYR
	γ-Glu-Tyr (gamma-Glutamyltyrosine) is a kokumi peptide with competitive inhibition of dipeptidyl peptidase-IV (DPP-IV) and is used in the study of diabetes mellitus.
T2385	Ipragliflozin	ASP1941	SGLT
	Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.		SGLT
T7133	Anagliptin	SK-0403	Proteasome , DPP-4
	Anagliptin (SK-0403) is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.		Proteasome , DPP-4
T27841	Lobeglitazone Sulfate	CKD501 Sulfate,CKD501,CKD-501 Sulfate,CKD 501 Sulfate,CKD 501,CKD-501,Lobeglitazone Sulfate. trade name Duvie, Chong Kun Dang	NOD
	Lobeglitazone Sulfate（CKD-501 Sulfate） is a novel thiazolidinedione with anti-inflammatory activity that inhibits LPS-induced NLRP3 inflammasome activation and hepatic inflammation, and can be used in the study of type 2...		NOD
T16479	PF-04937319		Others , Glucokinase
	PF-04937319 is an activator of glucokinase (EC50 =154.4 μM). PF-04937319 maintains glucose-lowering efficacy while mitigating the risk of hypoglycemia observed with many other glucokinase activators. PF-04937319 can be ...		Others , Glucokinase
T22387	NSC 55655	5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione	Others
	NSC 55655 (5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione) possesses antimicrobial and antioxidant activities and inhibits the proliferation of B. subtilis, S. aureus, K. pneumonia, E. coli, S. typhi , A. niger and C...		Others
T77781	Lotiglipron	PF-07081532	Glucagon Receptor
	Lotiglipron (PF-07081532) is an orally active and potent GLP-1R agonist that reduces blood glucose and body weight and may be useful in the study of type 2 diabetes mellitus (T2DM) and obesity.		Glucagon Receptor
T14283	Amyloid P-IN-1		Beta Amyloid
	amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, and type 2 diabetes mellitus.		Beta Amyloid
T37359	Myristoyl-L-carnitine chloride	L-Myristoylcarnitine chloride	Endogenous Metabolite
	Myristoyl-L-carnitine chloride (L-Myristoylcarnitine chloride) is one of the body's metabolites implicated in inherited metabolic disorders.Tetradecanoylcarnitine is a potential marker for the study of diabetes mellitus ...		Endogenous Metabolite
T1471	Duloxetine hydrochloride	Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl	Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
	Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and i...
T17315	(±)-CPSI-1306	cpsi-1306,2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholinoethan-1-one	Others
	(±)-CPSI-1306 (2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholinoethan-1-one) is a macrophage migration inhibitory factor (MIF) antagonist and can be used in studies about non-insulin-dependent diabetes mel...		Others
T36310	AKT-IN-6	INCB-047775	Akt
	AKT-IN-6 (INCB-047775) has an inhibitory effect on ATK. Akt is an important component of cellular signaling for growth factors, cytokines, and other cell stimuli. Abnormal Akt activation has been associated with the deve...		Akt
T78169	Enpp-1-IN-16		PDE
	Enpp-1-IN-16 is an inhibitor targeting ENPP1 with potential anti-cancer activity.Enpp-1-IN-16 can be used to study insulin resistance in relation to type II diabetes mellitus and various ENPP1-mediated diseases in the ch...		PDE
T68043	Ciamexon	Ciamexone,BM 41332,BM41332,BM-41332	Others
	Ciamexon (Ciamexone) is a novel immunomodulator that has shown promising results in experimental models of autoimmune disease with little demonstrated cytotoxicity.Ciamexon can be used to study endocrine ophthalmopathies...		Others
T0242	Sitagliptin	MK0431	Proteasome , DPP-4 , Autophagy
	Sitagliptin (MK0431), a new oral hypoglycemic (anti-diabetic drug), is a new dipeptidyl peptidase-4 (DPP-4) inhibitor. This enzyme-inhibiting drug is used either alone or in combination with metformin or thiazolidinedion...		Proteasome , DPP-4 , Autophagy
T4460	Dapagliflozin ((2S)-1,2-propanediol, hydrate)	BMS-512148 (2S)-1,2-propanediol, hydrate,Dapagliflozin propanediol monohydrate	SGLT
	Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2). It is in development for the tre...		SGLT
T14390L	(2R,3S)-Azelaprag		Apelin receptor
	(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist with an EC50 for Apelin receptors of 0.012 µM.(2R,3S)-N-(4-(...		Apelin receptor
T15810	LY2922470		GPR
	LY2922470 reduces glucose levels along with significant enhancements in insulin and GLP-1, which is the potential for the treatment of type 2 diabetes mellitus (T2DM). LY2922470 is an effective, selective, and orally ava...		GPR
T30149	AS-1669058 oxalate	AS-1669058,AS 1669058,AS1669058
	AS-1669058 is a G-protein-coupled receptor 119 (GPR119) agonist for the treatment of type 2 diabetes mellitus.
T11416	Glucagon receptor antagonists-5		Others
	Glucagon receptor antagonists-5 is an orally bioavailable indazole-based glucagon receptor antagonist (Ki: 32 nM). It has potential for the treatment of type 2 diabetes mellitus (T2DM).		Others
T11128	Dutogliptin	PHX-1149 free base	Others
	Dutogliptin (PHX-1149 free base) is an oral, effective and selective dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.		Others
T71181	GSK256073 Tris
	GSK256073 is an agonist of G-protein coupled receptor 109A (GPR109A). It acts by reducing serum glucose in subjects with type 2 diabetes mellitus.
T68500	AZD-2207
	AZD-2207 is a cannabinoid receptor CB1 antagonist and highly lipophilic compound for the treatment of type 2 diabetes mellitus and obesity.
T31263	Deanol aceglumate	Otrun,Deanolo aceglumato,Risatarun,Deanoli aceglumas
	Deanol aceglumate is combination of deanol and N-acetyl-L-glutamic acid. deanol aceglumate can effect Hepatoprotective on stress-induced gastropathy and diabetes mellitus.
T11127	Dutogliptin tartrate	PHX-1149	Others
	Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.		Others

Compounds

Target: Proteasome, DPP-4

Target: Glucocorticoid Receptor

Chembridge-5861528

T2711

Synonym: TCS 5861528

Target: TRP/TRPV Channel

VULM 1457

T23521

Synonym:

Target: Acyltransferase

Repaglinide

T1088

Synonym: AG-EE 388 ZW,AG-EE 623ZW

Target: Potassium Channel, PPAR

AMG131

T8780

Synonym: INT-131,AMG-131,CHS 131

Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy

Gemigliptin Tartrate(911637-19-9 free base)

T7369L

Synonym: LC15-0444 tartrate

Target: Proteasome, DPP-4

Glipizide

T1603

Synonym: CP 28720,K 4024

Target: Potassium Channel, PPAR, ABC

Rosiglitazone hydrochloride

T6646

Synonym: BRL-49653 HCl,Rosiglitazone HCl

Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy

Trelagliptin succinate

T2296

Synonym: SYR-472 succinate,SYR472

Target: Proteasome, DPP-4

Deferoxamine Mesylate

T1637

Synonym: desferrioxamine B,Desferrioxamine B mesylate,DFO,DFOM

Target: Mitophagy, Beta Amyloid, Others, Ferroptosis, HIF/HIF Prolyl-Hydroxylase, Autophagy

Target: Proteasome, DPP-4

Target: HIF/HIF Prolyl-Hydroxylase, HIF, Autophagy

Adomeglivant

T14130

Synonym: LY2409021

Target: Glucagon Receptor

Albiglutide TFA (782500-75-8 free base)

TP1796

Synonym: Albiglutide TFA

Target: Glucagon Receptor

Lixisenatide acetate (320367-13-3 free base)

TP1469

Synonym: Lixisenatide acetate

Target: Glucagon Receptor

Ertugliflozin L-pyroglutamic acid

T15244

Synonym: PF-04971729 L-pyroglutamic acid

Target: Others, SGLT

γ-Glu-Tyr

T78223

Synonym: gamma-Glutamyltyrosine,gamma-GLU-TYR

Target: Proteasome, DPP-4

Lobeglitazone Sulfate

T27841

Synonym: CKD501 Sulfate,CKD501,CKD-501 Sulfate,CKD 501 Sulfate,CKD 501,CKD-501,Lobeglitazone Sulfate. trade name Duvie, Chong Kun Dang

Target: Others, Glucokinase

NSC 55655

T22387

Synonym: 5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione

Target: Glucagon Receptor

Myristoyl-L-carnitine chloride

T37359

Synonym: L-Myristoylcarnitine chloride

Target: Endogenous Metabolite

Duloxetine hydrochloride

T1471

Synonym: Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl

Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine

(±)-CPSI-1306

T17315

Synonym: cpsi-1306,2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholinoethan-1-one

Synonym: Ciamexone,BM 41332,BM41332,BM-41332

Target: Proteasome, DPP-4, Autophagy

Dapagliflozin ((2S)-1,2-propanediol, hydrate)

T4460

Synonym: BMS-512148 (2S)-1,2-propanediol, hydrate,Dapagliflozin propanediol monohydrate

Target: Apelin receptor

Synonym: AS-1669058,AS 1669058,AS1669058

Target:

Glucagon receptor antagonists-5

Synonym: PHX-1149 free base

Synonym: Otrun,Deanolo aceglumato,Risatarun,Deanoli aceglumas

カタログ番号	製品名	別名	ターゲット
TN1788	Isookanin		Amylase
	Isookanin shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with the IC50 value of 7.9 ± 0.53 μM. Isookanin is a potent inhibitor of α-amylase (IC50=0.447 mg/ml).		Amylase
T0247	Acarbose	BAY g 5421	Glucosidase
	Acarbose (BAY g 5421) is an inhibitor of α-Glucosidases with antihyperglycemic activity.		Glucosidase
T7846	Aegeline		Others , Antifungal
	Aegeline is an alkaloidal-amide, isolated from the leaves of Aegle marmelos and have shown antihyperglycemic as well as antidyslipidemic activities in the validated animal models of type 2 diabetes mellitus.		Others , Antifungal
T3675	1-Deoxynojirimycin	Duvoglustat,Moranoline,moranolin	PI3K , Glucosidase
	1-Deoxynojirimycin (Moranoline) is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus.		PI3K , Glucosidase
TN1449	Brandioside	2'-O-Acetylpoliumoside,2'-Acetylpoliumoside	Antioxidant
	Brandioside (2'-Acetylpoliumoside), a phenylpropanoid glycoside obtainable from Callicarpa dichotoma Raeuschel, Verbenaceae, has antioxidant activity, attenuates glutamate-induced neurotoxicity, and can be used in the st...		Antioxidant
T4854	Acetoacetic acid lithium salt	LithoTab acetoacetate,Lithium acetoacetate,Lithium 3-Oxobutyrate	Others , Endogenous Metabolite
	Acetoacetic acid lithium salt (Lithium 3-Oxobutyrate) is a weak organic acid that can be produced in the human liver under certain conditions of poor Metabolism leading to excessive fatty acid breakdown (diabetes mellitu...		Others , Endogenous Metabolite
T0461L	Berberine sulfate	AI3-61947,Berberin sulfate,Berberine sulphate,Berberal

T5528	Cyanidin Chloride		Antioxidant
	Cyanidin Chloride, the main phenolic antioxidant in the grape (Vitis vinifera), in particular in the liposomal forms, could be used for treatment of diabetes mellitus complications.		Antioxidant
T1273	Diacerein	Diacerhein,Fisiodar,Diacetylrhein	IL Receptor , Interleukin
	Diacerein (Fisiodar) is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including sevre ...		IL Receptor , Interleukin
T5S0384	Rhapontin	Ponticin,Rhaponiticin,Rhaponticin,Rhapontigenin glucoside	Apoptosis , Others
	1. Rhapontin (Ponticin) can alleviate liver steatosis and improve blood glucose and lipid profiles in KK/Ay diabetic mice, indicates that rhaponticin has a noticeable antidiabetic effect and could be potentially used as ...		Apoptosis , Others
T3S0364	L-Arginine	L-Arg,(S)-(+)-Arginine	IL Receptor , Endogenous Metabolite , NO Synthase
	1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate...		IL Receptor , Endogenous Metabolite , NO Synthase
T19117	3-Deoxyglucosone	3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose	GPX , Glucagon Receptor
	3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein amino groups to form advanced glycosylated end proteins (AGE...		GPX , Glucagon Receptor
T3S1612	Kuwanon G	Moracenin B,Kuwanone G	Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase
	1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a...
TN3972	Epimedokoreanin B		Apoptosis , Others , Antibacterial
	Epimedokoreanin B (EKB), an isoprenylated flavonoid isolated from Korean Epimedium, exhibited anticancer activity in human non-small cell lung cancer (NSCLC) A549 and NCI-H292 cells.Epimedokoreanin B also possesses anti-...		Apoptosis , Others , Antibacterial
T8274	3-Methyl-L-histidine		Endogenous Metabolite
	3-Methylhistidine belongs to the class of organic compounds known as histidine and derivatives. Histidine and derivatives are compounds containing cysteine or a derivative thereof resulting from reaction of cysteine at t...		Endogenous Metabolite
T78485	D-Glucosamine 6-phosphate	Glucosamine-6-phosphate	Endogenous Metabolite
	D-Glucosamine 6-phosphate, an endogenous metabolite produced by glutamine fructose-6-phosphate amidotransferase (GFAT), is utilized in studies related to diabetes mellitus [1].		Endogenous Metabolite
T79939	Quercetin 3-(6″-caffeoylsophoroside)
	Quercetin 3-(6″-caffeoylsophoroside) is an orally active compound exhibiting α-amylase inhibitory activity, with an IC50 value of 73.66 μg/mL, and demonstrates antidiabetic effects through the reduction of oxidative stre...
TN5119	Taxoquinone		Tyrosinase , Antifection
	Taxoquinone has strong antibacterial effect, it could be used as a promising antibacterial agent in food industry to inhibit the growth of certain important foodborne pathogens. It (100 ug/disc) displays potential antica...		Tyrosinase , Antifection

天然物製品

Target: Others, Antifungal

1-Deoxynojirimycin

T3675

Synonym: Duvoglustat,Moranoline,moranolin

Target: PI3K, Glucosidase

Brandioside

TN1449

Synonym: 2'-O-Acetylpoliumoside,2'-Acetylpoliumoside

Target: Antioxidant

Acetoacetic acid lithium salt

T4854

Synonym: LithoTab acetoacetate,Lithium acetoacetate,Lithium 3-Oxobutyrate

Target: Others, Endogenous Metabolite

Berberine sulfate

T0461L

Synonym: AI3-61947,Berberin sulfate,Berberine sulphate,Berberal

Synonym: Diacerhein,Fisiodar,Diacetylrhein

Target: IL Receptor, Interleukin

Rhapontin

T5S0384

Synonym: Ponticin,Rhaponiticin,Rhaponticin,Rhapontigenin glucoside

Target: Apoptosis, Others

L-Arginine

T3S0364

Synonym: L-Arg,(S)-(+)-Arginine

Target: IL Receptor, Endogenous Metabolite, NO Synthase

3-Deoxyglucosone

T19117

Synonym: 3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose

Target: GPX, Glucagon Receptor

kuwanon G

T3S1612

Synonym: Moracenin B,Kuwanone G

Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase

Epimedokoreanin B

TN3972

Synonym:

Target: Apoptosis, Others, Antibacterial

3-Methyl-L-histidine

T8274

Synonym:

Target: Endogenous Metabolite

D-Glucosamine 6-phosphate

T78485

Synonym: Glucosamine-6-phosphate

Target: Endogenous Metabolite

Quercetin 3-(6″-caffeoylsophoroside)

Target: Tyrosinase, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00395	Insulin Protein, Human, Recombinant	Human	Yeast
	INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsul...
TMPJ-00071	EPO/Erythropoietin Protein, Human, Recombinant (His)	Human	Human Cells
	Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoi...
TMPY-00639	EPO/Erythropoietin Protein, Human, Recombinant (hFc)	Human	HEK293
	Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-00443	EPO/Erythropoietin Protein, Mouse, Recombinant	Mouse	HEK293
	Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-03565	Mannan Binding Lectin/MBL2 Protein, Human, Recombinant	Human	CHO
	MBL (mannose-binding lectin) is primarily a liver-derived collagen-like serum protein, which binds sugar structures on micro-organisms and dying host cells and is one of the four known mediators that initiate activation ...
TMPY-01146	Insulin Receptor Protein, Human, Recombinant (long isoform, His)	Human	HEK293
	INSR (Insulin receptor), also known as CD22, is a transmembrane receptor that is activated by insulin. INSR belongs to the protein kinase superfamily and exists as a tetramer consisting of two alpha subunits and two beta...
TMPY-00853	IL-1RA Protein, Human, Recombinant	Human	E. coli
	Interleukin-1 receptor antagonist (IL-1RA) also known as IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A), and interleukin 1, beta (IL1B), and mo...
TMPY-01848	HMGB1 Protein, Human, Recombinant (aa 1-215, His)	Human	HEK293
	High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...
TMPY-02590	HMGB1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...
TMPJ-01141	IA2 Protein, Human, Recombinant (aa 687-979, His)	Human	E. coli
	Receptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. PTPRN contains 1 tyrosine-protein phosphatase domain, is expressed in neuroendo...
TMPJ-01139	IA2 Protein, Human, Recombinant (aa 576-950, His)	Human	E. coli
	Receptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. PTPRN contains 1 tyrosine-protein phosphatase domain, is expressed in neuroendo...
TMPK-01128	LRG1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Diabetic nephropathy (DN) is an important public health concern of increasing proportions and the leading cause of end-stage renal disease (ESRD) in diabetic patients. It is one of the most common long-term microvascular...
TMPJ-01140	IA2 Protein, Human, Recombinant (aa 607-686 & aa 795-888 , His)	Human	E. coli
	Receptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. PTPRN contains 1 tyrosine-protein phosphatase domain, is expressed in neuroendo...
TMPK-00526	LRG1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Diabetic nephropathy (DN) is an important public health concern of increasing proportions and the leading cause of end-stage renal disease (ESRD) in diabetic patients. It is one of the most common long-term microvascular...
TMPJ-00014	Resistin Protein, Human, Recombinant (His)	Human	E. coli
	Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into ...
TMPJ-01199	BTN2A1 Protein, Human, Recombinant (His)	Human	Human Cells
	Butyrophilin 2A1 (BTN2A1) is an approximately widely expressed and variably glycosylated type I transmembrane glycoprotein. Mature human Butyrophilin 2A1 consisits of a 220 amino acid (aa) extracellular domain with two i...
TMPY-04394	Glucokinase Protein, Human, Recombinant	Human	E. coli
	Glucokinase belongs to the bacterial glucokinase family. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in ...
TMPY-03962	AFM Protein, Human, Recombinant (His)	Human	HEK293
	Afamin is an 87 kDa glycoprotein with five predicted N-glycosylation sites. Afamin's glycan abundance contributes to conformational and chemical inhomogeneity presenting great challenges for molecular structure determina...
TMPY-04122	ATOX1 Protein, Human, Recombinant (His)	Human	E. coli
	ATOX1 is a cytoplasmic copper chaperone that interacts with the copper-binding domain of the membrane copper transporters ATP7A and ATP7B. ATOX1 has also been suggested to have a potential anti-oxidant activity. As the t...
TMPY-02986	EPO/Erythropoietin Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-00462	EPO/Erythropoietin Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-02073	EPO/Erythropoietin Protein, Rat, Recombinant (His)	Rat	Baculovirus-Insect Cells
	Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-04395	Insulin Receptor Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	INSR (Insulin receptor), also known as CD22, is a transmembrane receptor that is activated by insulin. INSR belongs to the protein kinase superfamily and exists as a tetramer consisting of two alpha subunits and two beta...
TMPY-00429	Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (mFc)	Mouse	HEK293
	MBL (mannose-binding lectin) is primarily a liver-derived collagen-like serum protein, which binds sugar structures on micro-organisms and dying host cells and is one of the four known mediators that initiate activation ...
TMPY-04322	Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	MBL (mannose-binding lectin) is primarily a liver-derived collagen-like serum protein, which binds sugar structures on micro-organisms and dying host cells and is one of the four known mediators that initiate activation ...
TMPY-01149	Insulin Receptor Protein, Human, Recombinant (short isoform, His)	Human	HEK293
	INSR (Insulin receptor), also known as CD22, is a transmembrane receptor that is activated by insulin. INSR belongs to the protein kinase superfamily and exists as a tetramer consisting of two alpha subunits and two beta...
TMPY-05283	Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated	Human	HEK293
	INSR (Insulin receptor), also known as CD22, is a transmembrane receptor that is activated by insulin. INSR belongs to the protein kinase superfamily and exists as a tetramer consisting of two alpha subunits and two beta...
TMPY-00852	IL-1RA Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin-1 receptor antagonist (IL-1RA) also known as IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A), and interleukin 1, beta (IL1B), and mo...
TMPY-05837	IL-1RA Protein, Rat, Recombinant (His)	Rat	E. coli
	Interleukin-1 receptor antagonist (IL-1RA) also known as IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A), and interleukin 1, beta (IL1B), and mo...
TMPY-05845	IL-1RA Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	Interleukin-1 receptor antagonist (IL-1RA) also known as IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A), and interleukin 1, beta (IL1B), and mo...
TMPY-03081	IL-1RA Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Interleukin-1 receptor antagonist (IL-1RA) also known as IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A), and interleukin 1, beta (IL1B), and mo...
TMPY-03427	HMGB1 Protein, Human, Recombinant (aa 57-158, His)	Human	E. coli
	High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...
TMPY-00822	HMGB1 Protein, Human, Recombinant (hFc)	Human	HEK293
	High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...