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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T75389 | Catechol O-methyltransferase | ||
Catechol O-methyltransferase (COMT) is a magnesium-dependent enzyme that mediates the transfer of methyl groups from S-adenosyl methionine to the hydroxyl group on dopamine, thus converting it to 3-methoxytyramine. COMT ... | |||
T1904 | SGI-1027 | DNA Methyltransferase Inhibitor II,SGI1027 | Apoptosis , DNA Methyltransferase |
SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT). The IC50 of SGI-1027(SGI1027) against DNMT1, DNMT3A, and DNMT3B are 6, 8, 7.5 μM, respectively. | |||
T8548 | Metoprine | Histone Methyltransferase , Antifolate , Histamine Receptor | |
Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity. | |||
T8381 | Amodiaquine | Others , Histone Methyltransferase , Parasite | |
Amodiaquine is a synthetic aminoquinoline, used to treat malaria. | |||
T2097 | C-7280948 | C7280948 | Histone Methyltransferase |
C-7280948 is a PRMT1 inhibitor. | |||
T6879 | LLY-507 | LLY507,LLY 507 | Histone Methyltransferase |
LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2. | |||
T3624 | A-366 | A 366,A366 | Epigenetic Reader Domain , Histone Methyltransferase |
A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.It is more than 1,000-fold selective for G9a and GLP over the other 21 met... | |||
T13780 | MS1943 | Apoptosis , Histone Methyltransferase | |
MS1943 is a orally bioavailable EZH2 selective degrader(IC50 of 120 nM). | |||
T1841 | UNC0379 | Histone Methyltransferase | |
UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8. | |||
T7194 | CM-272 | Apoptosis , DNA Methyltransferase , Histone Methyltransferase | |
CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor. | |||
T15194 | EBI-2511 | Histone Methyltransferase | |
EBI-2511 is a highly potent and orally active inhibitor of EZH2 (IC50: 6 nM in Pfeffiera cell lines). | |||
T2435 | EPZ011989 | Histone Methyltransferase | |
EPZ011989 is a effective, specific orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 Y646 and EZH2 wt; 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase. | |||
TQ0100 | AZ505 | Histone Methyltransferase | |
AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 μM). | |||
T7089 | SGC2085 | Histone Methyltransferase | |
SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM). | |||
T15624 | JNJ-64619178 | Histone Methyltransferase | |
JNJ-64619178 is a selective, orally active, and pseudo-irreversible inhibitor of protein arginine methyltransferase 5 (IC50: 0.14 nM). It has effective activity In lung cancer. | |||
T6059 | GSK343 | Histone Methyltransferase , Autophagy | |
GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity against other histone methyltransferases. | |||
T3081 | EPZ004777 | Apoptosis , Histone Methyltransferase | |
EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM. | |||
T6900 | MS023 | Histone Methyltransferase | |
MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8, respectively. | |||
T1905 | EPZ005687 | Histone Methyltransferase | |
EPZ005687 is a potent and selective inhibitor of EZH2. | |||
T7403 | BAY-598 | Histone Methyltransferase | |
BAY-598 is a selective inhibitor of SMYD2 with IC50 values of 27 nM. | |||
T1775 | GSK503 | Histone Methyltransferase | |
GSK-503, a potent EZH2 inhibitor, has potential antitumor activity. | |||
T3084 | SGC707 | Histone Methyltransferase | |
SGC707 is a potent, selective, and cell-active allosteric inhibitor of PRMT3. | |||
T3057 | UNC1999 | Histone Methyltransferase , Autophagy | |
UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45). | |||
T14841 | BVT948 | Phosphatase , P450 , Histone Methyltransferase | |
BVT948 is a protein tyrosine phosphatase (PTP) inhibitor. It can also inhibit several CYP450 isoforms and lysine methyltransferase SETD8 (KMT5A). | |||
T15080 | DC-05 | DNA Methyltransferase , Histone Methyltransferase | |
DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively). | |||
T4021 | UNC3866 | Histone Methyltransferase | |
UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen. | |||
T5322 | BCI-121 | Histone Methyltransferase | |
BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell. | |||
T15201 | MAK683 | Histone Methyltransferase | |
MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay). | |||
T9584 | UNC6934 | Others , Histone Methyltransferase | |
UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2. | |||
T10205 | A-395 | Histone Methyltransferase | |
A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12, IC50: 18 nM). | |||
T3257 | UNC0638 | Influenza Virus , Histone Methyltransferase , Autophagy | |
UNC0638 is an inhibitor of β-protein lysine methyltransferases G9a(IC50<15 nM) and GLP(IC50=19 nM) with excellent potency and selectivity over a wide range of epigenetic and non-epigenetic targets. | |||
T4166 | UNC0642 | UNC-0642,UNC 0642 | Histone Methyltransferase |
UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM). | |||
T13954 | UNC6852 | Histone Methyltransferase , Ligands for Target Protein for PROTAC | |
UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC. | |||
T3099 | Pinometostat | EPZ-5676 | Histone Methyltransferase |
Pinometostat (EPZ-5676) has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Acute Lymphocytic Leukemia, among others. | |||
T3458 | EED226 | Histone Methyltransferase | |
EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM. | |||
T27133 | DCLX069 | DCLX 069,DCLX-069 | Histone Methyltransferase |
DCLX069 is a potent and selective PRMT1 inhibitor. DCLX069 occupies the SAM binding pocket to exert the inhibitory effect. DCLX069 effectively blocks cell proliferation in breast cancer, liver cancer and acute myeloid le... | |||
T7718 | 5-Fluoro-2'-deoxycytidine | FdCyd,2'-DEOXY-5-FLUOROCYTIDINE | DNA Methyltransferase |
5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) . | |||
T4343 | A-196 | A 196 | Histone Methyltransferase |
A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively; more than 100-fold selective over other histone methyltransferases and non-epigenetic targets. | |||
T7305 | JQEZ5 | Histone Methyltransferase | |
JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM). | |||
T36631 | BAY-6035 | MEK , Histone Methyltransferase | |
BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more than 100-fold selectivity over other histone methyltransferases. | |||
T0381 | Amodiaquine dihydrochloride dihydrate | Amodiaquine hydrochloride,Amodiaquin dihydrochloride dihydrate | Histone Methyltransferase , Parasite , Histamine Receptor |
Amodiaquine dihydrochloride dihydrate (Amodiaquine hydrochloride) is the hydrochloride salt of amodiaquine, an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties. | |||
T2379 | UNC1215 | Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase | |
UNC1215, an effective and specific MBT (malignant brain tumor) antagonist, binds L3MBTL3 (IC50/Kd: 40/120 nM). The selectivity of UNC1215 for L3MBTL3 is 50-fold higher versus other members of the human MBT family. | |||
T2495 | Lomeguatrib | PaTrin-2 | DNA Methyltransferase , DNA Alkylation |
Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) . | |||
T40254 | MRTX-1719 | Histone Methyltransferase | |
MRTX-1719 is a potent, first-in-class, selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAP DEL SDMA cells. | |||
T17204 | UNC0321 | Histone Methyltransferase | |
UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays. UNC0321 inhibits GLP with IC50s of 15 nM and 23 nM in ECSD and CLOT assays. | |||
T2352 | AMI-1 | Histone Methyltransferase | |
AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast Hmt1p, and human PRMT1). | |||
T5198 | Bobcat339 | Bobcat339 hydrochloride | DNA Methyltransferase |
Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a. | |||
T21767 | MS37452 | Others , Histone Methyltransferase | |
MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM). | |||
T12428L | PF-06726304 | Histone Methyltransferase | |
PF-06726304 shows robust antitumor growth activity. PF-06726304 is an effective and selective EZH2 inhibitor. PF-06726304 inhibits wild-type and Y641N mutant EZH2 (Kis: 0.7 and 3.0 nM, respectively). | |||
T5605 | EZM 2302 | GSK3359088 | Histone Methyltransferase |
EZM 2302 (GSK3359088) is a selective, and orally available arginine methyltransferase CARM1 inhibitor (IC50: 6 nM). |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T8201 | Gambogenic acid | Histone Methyltransferase | |
Gambogenic acid is a natural product,is an effective inhibitor of EZH2,with anticancer activity. | |||
T6803 | Chaetocin | Histone Methyltransferase , Antibacterial , Antibiotic | |
Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively. | |||
T3717 | Hinokitiol | 4-Isopropyltropolone,β-thujaplicin | DNA Methyltransferase , Virus Protease , Estrogen/progestogen Receptor , Nrf2 |
Hinokitiol (4-Isopropyltropolone) can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activity of metallothionein induced by the agent... | |||
T3606 | γ-Oryzanol | Gamma-Oryzanol,Oliver,Gammariza | DNA Methyltransferase |
γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the destruction of free radicals in the skin. It has recently b... | |||
T7457 | 5-Methyl-2'-deoxycytidine | 5-Methyldeoxycytidine,5MedCyd | DNA Methyltransferase , Endogenous Metabolite |
5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo. | |||
T1508 | Decitabine | Dacogen,NSC 127716,Deoxycytidine,5-Aza-2'-deoxycytidine | Apoptosis , Nucleoside Antimetabolite/Analog , DNA Methyltransferase |
Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis... | |||
T1339 | 5-Azacytidine | Azacitidine,NSC 102816,Mylosar,Ladakamycin,5-AzaC | Nucleoside Antimetabolite/Analog , DNA Methyltransferase , Antibacterial , Antibiotic , Autophagy |
5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity. 5-Azacytidine regulates gene expression by decreasing the level of DNA methylation. 5-Azacytidine induces autopha... | |||
T2209 | Serotonin hydrochloride | 5-HT hydrochloride,5-HT HCl,Serotonin HCl,5-Hydroxytryptamine hydrochloride | 5-HT Receptor , Endogenous Metabolite , Transferase |
Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (COMT) inhibitor(Ki=44 μM). | |||
T8790 | 1-Methylhistamine dihydrochloride | Endogenous Metabolite | |
1-Methylhistamine dihydrochloride is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of histaminergic system activity in the brains... | |||
T1354 | N-Acetyl-5-hydroxytryptamine | Normelatonin,O-Demethylmelatonin,N-Acetylserotonin | Trk receptor , Endogenous Metabolite |
N-Acetyl-5-hydroxytryptamine (O-Demethylmelatonin) , also known as Normelatonin, is the immediate precursor of melatonin. It is produced from serotonin by the enzyme aralkylamine N-acetyltransferase and is converted to m... | |||
T4861 | Trans-Aconitic acid | ATPase , Endogenous Metabolite | |
Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic acid is a substrate of enzyme trans-aco... | |||
T2988 | (-)-Epigallocatechin Gallate | Epigallocatechol Gallate,EGCG | Ferroptosis , Reactive Oxygen Species , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite , Autophagy |
(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate (EGCG) blocks the activation of EGF receptors and HER-2 receptor... | |||
T4120 | N-Methylsarcosine | N,N-Dimethylglycine,N,N-Dimethylaminoacetic acid,Dimethylglycine,DMG | Endogenous Metabolite |
N-Methylsarcosine (Dimethylglycine) is used as an athletic performance enhancer and immunostimulant. It is also used in the treatment of autism, epilepsy and mitochondrial disease. It is also employed as a biomarker of p... | |||
T4909 | N-Acetyl-DL-methionine | Others , Endogenous Metabolite | |
N-acetyl-L-methionine is nutritionally and metabolically equivalent to L-methionine. Methionine is a dietary indispensable amino acid required for normal growth and development of humans, other mammals, and avian species... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPJ-01429 | SARS-CoV-2 Guanine-N7 methyltransferase Protein (His) | SARS-CoV-2 | E. coli |
The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and ds... | |||
TMPY-05693 | SARS-CoV-2 Methyltransferase/ME Protein (His) | SARS-CoV-2 | E. coli |
Coronavirus encodes the 2’-O-MTase (2'O Methyltransferase) that is composed of the catalytic subunit nsp16 and the stimulatory subunit nsp10 and plays an important role in virus genome replication and evasion from innate... | |||
TMPJ-01118 | GNMT Protein, Human, Recombinant (His) | Human | E. coli |
Glycine N-Methyltransferase (GNMT) is a tetrameric cytosolic protein. GNMT catalyzes the synthesis of N-methylglycine from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. It can affects DNA methylation b... | |||
TMPK-01308 | TAG-72 Protein, Canine, Recombinant (His) | Canine | E. coli |
The guanine-N7 methyltransferase domain of vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit and a stimulatory subunit. Cap (guanine-N7) methylation is an essential step in eukaryal mRNA... | |||
TMPH-00878 | ASMT Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2 and isoform 3 lack enzyme activity. ASMT Protein, Human, Recombinant (His & Myc) is... | |||
TMPY-01270 | PRMT3 Protein, Human, Recombinant (GST) | Human | E. coli |
Protein arginine methyltransferase 3, also known as PRMT3, is one of four type I protein arginine methyltransferases (PRMT) that in humans is encoded by the PRMT3 gene. Methylation of arginine residues is a widespread po... | |||
TMPH-02635 | EEF1AKMT2 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'. EEF1AKMT2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted... | |||
TMPY-01383 | PRMT6 Protein, Human, Recombinant (His & Flag) | Human | HEK293 Cells |
Protein arginine N-methyltransferase 6, also known as Histone-arginine N-methyltransferase PRMT6, PRMT6, and HRMT1L6, is a member of the protein arginine N-methyltransferase family and PRMT6 subfamily. PRMT6 is highly ex... | |||
TMPH-02564 | CARNMT1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of ... | |||
TMPY-05158 | COMT Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
COMT Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 31.5 kDa and the accession number is A0A140VJG8. | |||
TMPJ-01114 | GAMT Protein, Human, Recombinant (His) | Human | E. coli |
GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily. It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver. GAMT converts guanidoa... | |||
TMPH-00313 | TRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His) | Brugia malayi | E. coli |
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. tRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. ... | |||
TMPY-02340 | HNMT Protein, Human, Recombinant (GST) | Human | E. coli |
HNMT (Histamine N-methyltransferase) is a Protein Coding gene. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. HNMT, the major enzyme for the metabol... | |||
TMPY-01708 | DOT1L Protein, Human, Recombinant | Human | E. coli |
Histone-lysine N-methyltransferase, H3 lysine-79 specific, also known as Histone H3-K79 methyltransferase, DOT1-like protein, Lysine N-methyltransferase 4 and DOT1L, is a nucleus protein which belongs to theDOT1 famil... | |||
TMPY-01661 | METTL1 Protein, Human, Recombinant (His) | Human | E. coli |
tRNA (guanine-N(7)-)-methyltransferase, also known as Methyltransferase-like protein 1, tRNA (m7G46)-methyltransferase and METTL1, is a nucleus protein that belongs to the methyltransferase superfamily and TrmB family. M... | |||
TMPH-01970 | EEF2KMT Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the trimethylation of eukaryotic elongation factor 2 (EEF2) on 'Lys-525'. EEF2KMT Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is ... | |||
TMPY-01306 | DNMT2 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
DNMT2, also known as tRNA (cytosine-5-)-methyltransferase, DNA methyltransferase homolog HsaIIP, and TRDMT1, is a member of the DNA methyltransferase family of enzymes. DNMT2 enzymes have been widely conserved during evo... | |||
TMPY-00279 | Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His) | DENV | E. coli |
Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35.5 kDa and the ac... | |||
TMPH-02105 | ASH2L Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 ... | |||
TMPY-01584 | PR-Set7 Protein, Human, Recombinant | Human | E. coli |
KMT5A (known as PR-Set7/9, SETD8 and SET8), a member of the SET domain containing methyltransferase family specifically targeting H4K20 for methylation, has been implicated in multiple biological processes. Inhibition of... | |||
TMPY-01285 | METTL11A Protein, Human, Recombinant | Human | E. coli |
METTL11A Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 25.5 kDa and the accession number is A0A024R8E4. | |||
TMPY-01229 | SETD7 Protein, Human, Recombinant (His) | Human | E. coli |
Histone-lysine N-methyltransferase SETD7, also known as SET domain containing (lysine methyltransferase) 7, SET7/9, Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, and SETD7, is a member of the histone-lysine ... | |||
TMPY-01284 | METTL11A Protein, Human, Recombinant (GST) | Human | E. coli |
METTL11A Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 52.2 kDa and the accession number is A0A024R8E4. | |||
TMPY-02420 | HEMK2 Protein, Human, Recombinant (His) | Human | E. coli |
N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes an N(6)-adenine-specific DNA methyltransferase. It belongs to t... | |||
TMPJ-00872 | MGMT Protein, Human, Recombinant (His) | Human | E. coli |
MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. MGMT involved in the cellular defense against the biological effects of O6-methylguanine in DNA. Repairs al... | |||
TMPH-01680 | METTL25 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Probable methyltransferase. | |||
TMPY-01657 | SUV420H2 Protein, Human, Recombinant (His & GST) | Human | E. coli |
Histone-lysine N-methyltransferase SUV42H2, also known as Suppressor of variegation 4-2 homolog 2, Su(var)4-2 homolog 2, Lysine N-methyltransferase 5C, SUV42H2 and KMT5C, is nucleus protein that belongs to the histone-ly... | |||
TMPH-01682 | METTL7B Protein, Human, Recombinant (His) | Human | E. coli |
Thiol S-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-l-methionine to hydrogen sulfide and other thiol compounds including dithiothreitol, 7alpha-thiospironolactone, L-penicillamine, and... | |||
TMPH-02227 | ERG Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure. ERG Protein, Human, Recombina... | |||
TMPH-01529 | INMT Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, ... | |||
TMPY-01268 | SMYD3 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger... | |||
TMPY-03046 | APCDD1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Osteosarcoma (OS) is the most common type of bone tumor in children and adults. The expression of APCDD1, a Wnt antagonist, was reduced in OS tissues and cells compared to adjacent normal tissue and osteoblast cells, res... | |||
TMPJ-01040 | MAX Protein, Human, Recombinant (His) | Human | E. coli |
Myc-Associated Factor X (MAX) is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It contains 1 basic helix-loop-helix (bHLH) domain. It is found in the brain, heart, and lun... | |||
TMPY-04770 | RIOK1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
RIOK1, also known as RIO kinase 1, is a member of the RIO family of atypical serine protein kinases first characterized in yeast. RIOK1 and RIOK2 proteins are present in organisms from Archaea to humans. RIOK1 functions ... | |||
TMPY-02888 | MAX Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
MYC associated factor X contains 1 basic helix-loop-helix (bHLH) domain and belongs to the MAX family. It is highly expressed in the brain, heart, and lung while lower levels are seen in the liver, kidney, and skeletal m... | |||
TMPY-04403 | NLK/Nemo Like Kinase Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Nemo-like kinase contains 1 protein kinase domain and belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. It also contains a TQE activation loop motif in which autopho... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L1710 | Anti-COVID-19 Compound Library | 1133 compounds | |
A unique collection of 1133 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents; |