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Search Results for " methyltransferase "

ターゲット

265

阻害剤

14

天然化合物

36

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T75389 Catechol O-methyltransferase
Catechol O-methyltransferase (COMT) is a magnesium-dependent enzyme that mediates the transfer of methyl groups from S-adenosyl methionine to the hydroxyl group on dopamine, thus converting it to 3-methoxytyramine. COMT ...
T1904 SGI-1027 DNA Methyltransferase Inhibitor II,SGI1027 Apoptosis , DNA Methyltransferase
SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT). The IC50 of SGI-1027(SGI1027) against DNMT1, DNMT3A, and DNMT3B are 6, 8, 7.5 μM, respectively.
T8548 Metoprine Histone Methyltransferase , Antifolate , Histamine Receptor
Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.
T8381 Amodiaquine Others , Histone Methyltransferase , Parasite
Amodiaquine is a synthetic aminoquinoline, used to treat malaria.
T2097 C-7280948 C7280948 Histone Methyltransferase
C-7280948 is a PRMT1 inhibitor.
T6879 LLY-507 LLY507,LLY 507 Histone Methyltransferase
LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.
T3624 A-366 A 366,A366 Epigenetic Reader Domain , Histone Methyltransferase
A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.It is more than 1,000-fold selective for G9a and GLP over the other 21 met...
T13780 MS1943 Apoptosis , Histone Methyltransferase
MS1943 is a orally bioavailable EZH2 selective degrader(IC50 of 120 nM).
T1841 UNC0379 Histone Methyltransferase
UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.
T7194 CM-272 Apoptosis , DNA Methyltransferase , Histone Methyltransferase
CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.
T15194 EBI-2511 Histone Methyltransferase
EBI-2511 is a highly potent and orally active inhibitor of EZH2 (IC50: 6 nM in Pfeffiera cell lines).
T2435 EPZ011989 Histone Methyltransferase
EPZ011989 is a effective, specific orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 Y646 and EZH2 wt; 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase.
TQ0100 AZ505 Histone Methyltransferase
AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 μM).
T7089 SGC2085 Histone Methyltransferase
SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).
T15624 JNJ-64619178 Histone Methyltransferase
JNJ-64619178 is a selective, orally active, and pseudo-irreversible inhibitor of protein arginine methyltransferase 5 (IC50: 0.14 nM). It has effective activity In lung cancer.
T6059 GSK343 Histone Methyltransferase , Autophagy
GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity against other histone methyltransferases.
T3081 EPZ004777 Apoptosis , Histone Methyltransferase
EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.
T6900 MS023 Histone Methyltransferase
MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8, respectively.
T1905 EPZ005687 Histone Methyltransferase
EPZ005687 is a potent and selective inhibitor of EZH2.
T7403 BAY-598 Histone Methyltransferase
BAY-598 is a selective inhibitor of SMYD2 with IC50 values of 27 nM.
T1775 GSK503 Histone Methyltransferase
GSK-503, a potent EZH2 inhibitor, has potential antitumor activity.
T3084 SGC707 Histone Methyltransferase
SGC707 is a potent, selective, and cell-active allosteric inhibitor of PRMT3.
T3057 UNC1999 Histone Methyltransferase , Autophagy
UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).
T14841 BVT948 Phosphatase , P450 , Histone Methyltransferase
BVT948 is a protein tyrosine phosphatase (PTP) inhibitor. It can also inhibit several CYP450 isoforms and lysine methyltransferase SETD8 (KMT5A).
T15080 DC-05 DNA Methyltransferase , Histone Methyltransferase
DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).
T4021 UNC3866 Histone Methyltransferase
UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.
T5322 BCI-121 Histone Methyltransferase
BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.
T15201 MAK683 Histone Methyltransferase
MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).
T9584 UNC6934 Others , Histone Methyltransferase
UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.
T10205 A-395 Histone Methyltransferase
A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12, IC50: 18 nM).
T3257 UNC0638 Influenza Virus , Histone Methyltransferase , Autophagy
UNC0638 is an inhibitor of β-protein lysine methyltransferases G9a(IC50<15 nM) and GLP(IC50=19 nM) with excellent potency and selectivity over a wide range of epigenetic and non-epigenetic targets.
T4166 UNC0642 UNC-0642,UNC 0642 Histone Methyltransferase
UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM).
T13954 UNC6852 Histone Methyltransferase , Ligands for Target Protein for PROTAC
UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC.
T3099 Pinometostat EPZ-5676 Histone Methyltransferase
Pinometostat (EPZ-5676) has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Acute Lymphocytic Leukemia, among others.
T3458 EED226 Histone Methyltransferase
EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.
T27133 DCLX069 DCLX 069,DCLX-069 Histone Methyltransferase
DCLX069 is a potent and selective PRMT1 inhibitor. DCLX069 occupies the SAM binding pocket to exert the inhibitory effect. DCLX069 effectively blocks cell proliferation in breast cancer, liver cancer and acute myeloid le...
T7718 5-Fluoro-2'-deoxycytidine FdCyd,2'-DEOXY-5-FLUOROCYTIDINE DNA Methyltransferase
5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .
T4343 A-196 A 196 Histone Methyltransferase
A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively; more than 100-fold selective over other histone methyltransferases and non-epigenetic targets.
T7305 JQEZ5 Histone Methyltransferase
JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).
T36631 BAY-6035 MEK , Histone Methyltransferase
BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more than 100-fold selectivity over other histone methyltransferases.
T0381 Amodiaquine dihydrochloride dihydrate Amodiaquine hydrochloride,Amodiaquin dihydrochloride dihydrate Histone Methyltransferase , Parasite , Histamine Receptor
Amodiaquine dihydrochloride dihydrate (Amodiaquine hydrochloride) is the hydrochloride salt of amodiaquine, an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties.
T2379 UNC1215 Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
UNC1215, an effective and specific MBT (malignant brain tumor) antagonist, binds L3MBTL3 (IC50/Kd: 40/120 nM). The selectivity of UNC1215 for L3MBTL3 is 50-fold higher versus other members of the human MBT family.
T2495 Lomeguatrib PaTrin-2 DNA Methyltransferase , DNA Alkylation
Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .
T40254 MRTX-1719 Histone Methyltransferase
MRTX-1719 is a potent, first-in-class, selective inhibitor of the PRMT5/MTA complex, with an IC50 of less than 10 nM in PRMT5/MTA MTAP DEL SDMA cells.
T17204 UNC0321 Histone Methyltransferase
UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays. UNC0321 inhibits GLP with IC50s of 15 nM and 23 nM in ECSD and CLOT assays.
T2352 AMI-1 Histone Methyltransferase
AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast Hmt1p, and human PRMT1).
T5198 Bobcat339 Bobcat339 hydrochloride DNA Methyltransferase
Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.
T21767 MS37452 Others , Histone Methyltransferase
MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM).
T12428L PF-06726304 Histone Methyltransferase
PF-06726304 shows robust antitumor growth activity. PF-06726304 is an effective and selective EZH2 inhibitor. PF-06726304 inhibits wild-type and Y641N mutant EZH2 (Kis: 0.7 and 3.0 nM, respectively).
T5605 EZM 2302 GSK3359088 Histone Methyltransferase
EZM 2302 (GSK3359088) is a selective, and orally available arginine methyltransferase CARM1 inhibitor (IC50: 6 nM).

Compounds

Catechol O-methyltransferase
T75389
Synonym:
Target:
SGI-1027
T1904
Synonym: DNA Methyltransferase Inhibitor II,SGI1027
Target: Apoptosis, DNA Methyltransferase
Metoprine
T8548
Synonym:
Target: Histone Methyltransferase, Antifolate, Histamine Receptor
Amodiaquine
T8381
Synonym:
Target: Others, Histone Methyltransferase, Parasite
C-7280948
T2097
Synonym: C7280948
Target: Histone Methyltransferase
LLY-507
T6879
Synonym: LLY507,LLY 507
Target: Histone Methyltransferase
A-366
T3624
Synonym: A 366,A366
Target: Epigenetic Reader Domain, Histone Methyltransferase
MS1943
T13780
Synonym:
Target: Apoptosis, Histone Methyltransferase
UNC0379
T1841
Synonym:
Target: Histone Methyltransferase
CM-272
T7194
Synonym:
Target: Apoptosis, DNA Methyltransferase, Histone Methyltransferase
EBI-2511
T15194
Synonym:
Target: Histone Methyltransferase
EPZ011989
T2435
Synonym:
Target: Histone Methyltransferase
AZ505
TQ0100
Synonym:
Target: Histone Methyltransferase
SGC2085
T7089
Synonym:
Target: Histone Methyltransferase
JNJ-64619178
T15624
Synonym:
Target: Histone Methyltransferase
GSK343
T6059
Synonym:
Target: Histone Methyltransferase, Autophagy
EPZ004777
T3081
Synonym:
Target: Apoptosis, Histone Methyltransferase
MS023
T6900
Synonym:
Target: Histone Methyltransferase
EPZ005687
T1905
Synonym:
Target: Histone Methyltransferase
BAY-598
T7403
Synonym:
Target: Histone Methyltransferase
GSK503
T1775
Synonym:
Target: Histone Methyltransferase
SGC707
T3084
Synonym:
Target: Histone Methyltransferase
UNC1999
T3057
Synonym:
Target: Histone Methyltransferase, Autophagy
BVT948
T14841
Synonym:
Target: Phosphatase, P450, Histone Methyltransferase
DC-05
T15080
Synonym:
Target: DNA Methyltransferase, Histone Methyltransferase
UNC3866
T4021
Synonym:
Target: Histone Methyltransferase
BCI-121
T5322
Synonym:
Target: Histone Methyltransferase
MAK683
T15201
Synonym:
Target: Histone Methyltransferase
UNC6934
T9584
Synonym:
Target: Others, Histone Methyltransferase
A-395
T10205
Synonym:
Target: Histone Methyltransferase
UNC0638
T3257
Synonym:
Target: Influenza Virus, Histone Methyltransferase, Autophagy
UNC0642
T4166
Synonym: UNC-0642,UNC 0642
Target: Histone Methyltransferase
UNC6852
T13954
Synonym:
Target: Histone Methyltransferase, Ligands for Target Protein for PROTAC
Pinometostat
T3099
Synonym: EPZ-5676
Target: Histone Methyltransferase
EED226
T3458
Synonym:
Target: Histone Methyltransferase
DCLX069
T27133
Synonym: DCLX 069,DCLX-069
Target: Histone Methyltransferase
5-Fluoro-2'-deoxycytidine
T7718
Synonym: FdCyd,2'-DEOXY-5-FLUOROCYTIDINE
Target: DNA Methyltransferase
A-196
T4343
Synonym: A 196
Target: Histone Methyltransferase
JQEZ5
T7305
Synonym:
Target: Histone Methyltransferase
BAY-6035
T36631
Synonym:
Target: MEK, Histone Methyltransferase
Amodiaquine dihydrochloride dihydrate
T0381
Synonym: Amodiaquine hydrochloride,Amodiaquin dihydrochloride dihydrate
Target: Histone Methyltransferase, Parasite, Histamine Receptor
UNC1215
T2379
Synonym:
Target: Apoptosis, Epigenetic Reader Domain, Histone Methyltransferase
Lomeguatrib
T2495
Synonym: PaTrin-2
Target: DNA Methyltransferase, DNA Alkylation
MRTX-1719
T40254
Synonym:
Target: Histone Methyltransferase
UNC0321
T17204
Synonym:
Target: Histone Methyltransferase
AMI-1
T2352
Synonym:
Target: Histone Methyltransferase
Bobcat339
T5198
Synonym: Bobcat339 hydrochloride
Target: DNA Methyltransferase
MS37452
T21767
Synonym:
Target: Others, Histone Methyltransferase
PF-06726304
T12428L
Synonym:
Target: Histone Methyltransferase
EZM 2302
T5605
Synonym: GSK3359088
Target: Histone Methyltransferase
1 2 3 4 5 6
カタログ番号 製品名 別名 ターゲット
T8201 Gambogenic acid Histone Methyltransferase
Gambogenic acid is a natural product,is an effective inhibitor of EZH2,with anticancer activity.
T6803 Chaetocin Histone Methyltransferase , Antibacterial , Antibiotic
Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively.
T3717 Hinokitiol 4-Isopropyltropolone,β-thujaplicin DNA Methyltransferase , Virus Protease , Estrogen/progestogen Receptor , Nrf2
Hinokitiol (4-Isopropyltropolone) can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activity of metallothionein induced by the agent...
T3606 γ-Oryzanol Gamma-Oryzanol,Oliver,Gammariza DNA Methyltransferase
γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the destruction of free radicals in the skin. It has recently b...
T7457 5-Methyl-2'-deoxycytidine 5-Methyldeoxycytidine,5MedCyd DNA Methyltransferase , Endogenous Metabolite
5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.
T1508 Decitabine Dacogen,NSC 127716,Deoxycytidine,5-Aza-2'-deoxycytidine Apoptosis , Nucleoside Antimetabolite/Analog , DNA Methyltransferase
Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis...
T1339 5-Azacytidine Azacitidine,NSC 102816,Mylosar,Ladakamycin,5-AzaC Nucleoside Antimetabolite/Analog , DNA Methyltransferase , Antibacterial , Antibiotic , Autophagy
5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity. 5-Azacytidine regulates gene expression by decreasing the level of DNA methylation. 5-Azacytidine induces autopha...
T2209 Serotonin hydrochloride 5-HT hydrochloride,5-HT HCl,Serotonin HCl,5-Hydroxytryptamine hydrochloride 5-HT Receptor , Endogenous Metabolite , Transferase
Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (COMT) inhibitor(Ki=44 μM).
T8790 1-Methylhistamine dihydrochloride Endogenous Metabolite
1-Methylhistamine dihydrochloride is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of histaminergic system activity in the brains...
T1354 N-Acetyl-5-hydroxytryptamine Normelatonin,O-Demethylmelatonin,N-Acetylserotonin Trk receptor , Endogenous Metabolite
N-Acetyl-5-hydroxytryptamine (O-Demethylmelatonin) , also known as Normelatonin, is the immediate precursor of melatonin. It is produced from serotonin by the enzyme aralkylamine N-acetyltransferase and is converted to m...
T4861 Trans-Aconitic acid ATPase , Endogenous Metabolite
Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic acid is a substrate of enzyme trans-aco...
T2988 (-)-Epigallocatechin Gallate Epigallocatechol Gallate,EGCG Ferroptosis , Reactive Oxygen Species , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite , Autophagy
(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate (EGCG) blocks the activation of EGF receptors and HER-2 receptor...
T4120 N-Methylsarcosine N,N-Dimethylglycine,N,N-Dimethylaminoacetic acid,Dimethylglycine,DMG Endogenous Metabolite
N-Methylsarcosine (Dimethylglycine) is used as an athletic performance enhancer and immunostimulant. It is also used in the treatment of autism, epilepsy and mitochondrial disease. It is also employed as a biomarker of p...
T4909 N-Acetyl-DL-methionine Others , Endogenous Metabolite
N-acetyl-L-methionine is nutritionally and metabolically equivalent to L-methionine. Methionine is a dietary indispensable amino acid required for normal growth and development of humans, other mammals, and avian species...

天然物製品

Gambogenic acid
T8201
Synonym:
Target: Histone Methyltransferase
Chaetocin
T6803
Synonym:
Target: Histone Methyltransferase, Antibacterial, Antibiotic
Hinokitiol
T3717
Synonym: 4-Isopropyltropolone,β-thujaplicin
Target: DNA Methyltransferase, Virus Protease, Estrogen/progestogen Receptor, Nrf2
γ-Oryzanol
T3606
Synonym: Gamma-Oryzanol,Oliver,Gammariza
Target: DNA Methyltransferase
5-Methyl-2'-deoxycytidine
T7457
Synonym: 5-Methyldeoxycytidine,5MedCyd
Target: DNA Methyltransferase, Endogenous Metabolite
Decitabine
T1508
Synonym: Dacogen,NSC 127716,Deoxycytidine,5-Aza-2'-deoxycytidine
Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA Methyltransferase
5-Azacytidine
T1339
Synonym: Azacitidine,NSC 102816,Mylosar,Ladakamycin,5-AzaC
Target: Nucleoside Antimetabolite/Analog, DNA Methyltransferase, Antibacterial, Antibiotic, Autophagy
Serotonin hydrochloride
T2209
Synonym: 5-HT hydrochloride,5-HT HCl,Serotonin HCl,5-Hydroxytryptamine hydrochloride
Target: 5-HT Receptor, Endogenous Metabolite, Transferase
1-Methylhistamine dihydrochloride
T8790
Synonym:
Target: Endogenous Metabolite
N-Acetyl-5-hydroxytryptamine
T1354
Synonym: Normelatonin,O-Demethylmelatonin,N-Acetylserotonin
Target: Trk receptor, Endogenous Metabolite
trans-Aconitic acid
T4861
Synonym:
Target: ATPase, Endogenous Metabolite
(-)-Epigallocatechin Gallate
T2988
Synonym: Epigallocatechol Gallate,EGCG
Target: Ferroptosis, Reactive Oxygen Species, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite, Autophagy
N-Methylsarcosine
T4120
Synonym: N,N-Dimethylglycine,N,N-Dimethylaminoacetic acid,Dimethylglycine,DMG
Target: Endogenous Metabolite
N-Acetyl-DL-methionine
T4909
Synonym:
Target: Others, Endogenous Metabolite

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPJ-01429 SARS-CoV-2 Guanine-N7 methyltransferase Protein (His) SARS-CoV-2 E. coli
The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and ds...
TMPY-05693 SARS-CoV-2 Methyltransferase/ME Protein (His) SARS-CoV-2 E. coli
Coronavirus encodes the 2’-O-MTase (2'O Methyltransferase) that is composed of the catalytic subunit nsp16 and the stimulatory subunit nsp10 and plays an important role in virus genome replication and evasion from innate...
TMPJ-01118 GNMT Protein, Human, Recombinant (His) Human E. coli
Glycine N-Methyltransferase (GNMT) is a tetrameric cytosolic protein. GNMT catalyzes the synthesis of N-methylglycine from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. It can affects DNA methylation b...
TMPK-01308 TAG-72 Protein, Canine, Recombinant (His) Canine E. coli
The guanine-N7 methyltransferase domain of vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit and a stimulatory subunit. Cap (guanine-N7) methylation is an essential step in eukaryal mRNA...
TMPH-00878 ASMT Protein, Human, Recombinant (His & Myc) Human E. coli
Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2 and isoform 3 lack enzyme activity. ASMT Protein, Human, Recombinant (His & Myc) is...
TMPY-01270 PRMT3 Protein, Human, Recombinant (GST) Human E. coli
Protein arginine methyltransferase 3, also known as PRMT3, is one of four type I protein arginine methyltransferases (PRMT) that in humans is encoded by the PRMT3 gene. Methylation of arginine residues is a widespread po...
TMPH-02635 EEF1AKMT2 Protein, Mouse, Recombinant (His) Mouse E. coli
Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'. EEF1AKMT2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted...
TMPY-01383 PRMT6 Protein, Human, Recombinant (His & Flag) Human HEK293 Cells
Protein arginine N-methyltransferase 6, also known as Histone-arginine N-methyltransferase PRMT6, PRMT6, and HRMT1L6, is a member of the protein arginine N-methyltransferase family and PRMT6 subfamily. PRMT6 is highly ex...
TMPH-02564 CARNMT1 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of ...
TMPY-05158 COMT Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
COMT Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 31.5 kDa and the accession number is A0A140VJG8.
TMPJ-01114 GAMT Protein, Human, Recombinant (His) Human E. coli
GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily. It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver. GAMT converts guanidoa...
TMPH-00313 TRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His) Brugia malayi E. coli
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. tRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. ...
TMPY-02340 HNMT Protein, Human, Recombinant (GST) Human E. coli
HNMT (Histamine N-methyltransferase) is a Protein Coding gene. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. HNMT, the major enzyme for the metabol...
TMPY-01708 DOT1L Protein, Human, Recombinant Human E. coli
Histone-lysine N-methyltransferase, H3 lysine-79 specific, also known as Histone H3-K79 methyltransferase, DOT1-like protein, Lysine N-methyltransferase 4 and DOT1L, is a nucleus protein which belongs to theDOT1 famil...
TMPY-01661 METTL1 Protein, Human, Recombinant (His) Human E. coli
tRNA (guanine-N(7)-)-methyltransferase, also known as Methyltransferase-like protein 1, tRNA (m7G46)-methyltransferase and METTL1, is a nucleus protein that belongs to the methyltransferase superfamily and TrmB family. M...
TMPH-01970 EEF2KMT Protein, Human, Recombinant (His) Human E. coli
Catalyzes the trimethylation of eukaryotic elongation factor 2 (EEF2) on 'Lys-525'. EEF2KMT Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is ...
TMPY-01306 DNMT2 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
DNMT2, also known as tRNA (cytosine-5-)-methyltransferase, DNA methyltransferase homolog HsaIIP, and TRDMT1, is a member of the DNA methyltransferase family of enzymes. DNMT2 enzymes have been widely conserved during evo...
TMPY-00279 Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His) DENV E. coli
Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35.5 kDa and the ac...
TMPH-02105 ASH2L Protein, Human, Recombinant (His & SUMO) Human E. coli
Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 ...
TMPY-01584 PR-Set7 Protein, Human, Recombinant Human E. coli
KMT5A (known as PR-Set7/9, SETD8 and SET8), a member of the SET domain containing methyltransferase family specifically targeting H4K20 for methylation, has been implicated in multiple biological processes. Inhibition of...
TMPY-01285 METTL11A Protein, Human, Recombinant Human E. coli
METTL11A Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 25.5 kDa and the accession number is A0A024R8E4.
TMPY-01229 SETD7 Protein, Human, Recombinant (His) Human E. coli
Histone-lysine N-methyltransferase SETD7, also known as SET domain containing (lysine methyltransferase) 7, SET7/9, Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, and SETD7, is a member of the histone-lysine ...
TMPY-01284 METTL11A Protein, Human, Recombinant (GST) Human E. coli
METTL11A Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 52.2 kDa and the accession number is A0A024R8E4.
TMPY-02420 HEMK2 Protein, Human, Recombinant (His) Human E. coli
N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes an N(6)-adenine-specific DNA methyltransferase. It belongs to t...
TMPJ-00872 MGMT Protein, Human, Recombinant (His) Human E. coli
MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. MGMT involved in the cellular defense against the biological effects of O6-methylguanine in DNA. Repairs al...
TMPH-01680 METTL25 Protein, Human, Recombinant (His & Myc) Human E. coli
Probable methyltransferase.
TMPY-01657 SUV420H2 Protein, Human, Recombinant (His & GST) Human E. coli
Histone-lysine N-methyltransferase SUV42H2, also known as Suppressor of variegation 4-2 homolog 2, Su(var)4-2 homolog 2, Lysine N-methyltransferase 5C, SUV42H2 and KMT5C, is nucleus protein that belongs to the histone-ly...
TMPH-01682 METTL7B Protein, Human, Recombinant (His) Human E. coli
Thiol S-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-l-methionine to hydrogen sulfide and other thiol compounds including dithiothreitol, 7alpha-thiospironolactone, L-penicillamine, and...
TMPH-02227 ERG Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure. ERG Protein, Human, Recombina...
TMPH-01529 INMT Protein, Human, Recombinant (His & SUMO) Human E. coli
Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, ...
TMPY-01268 SMYD3 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger...
TMPY-03046 APCDD1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Osteosarcoma (OS) is the most common type of bone tumor in children and adults. The expression of APCDD1, a Wnt antagonist, was reduced in OS tissues and cells compared to adjacent normal tissue and osteoblast cells, res...
TMPJ-01040 MAX Protein, Human, Recombinant (His) Human E. coli
Myc-Associated Factor X (MAX) is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It contains 1 basic helix-loop-helix (bHLH) domain. It is found in the brain, heart, and lun...
TMPY-04770 RIOK1 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
RIOK1, also known as RIO kinase 1, is a member of the RIO family of atypical serine protein kinases first characterized in yeast. RIOK1 and RIOK2 proteins are present in organisms from Archaea to humans. RIOK1 functions ...
TMPY-02888 MAX Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
MYC associated factor X contains 1 basic helix-loop-helix (bHLH) domain and belongs to the MAX family. It is highly expressed in the brain, heart, and lung while lower levels are seen in the liver, kidney, and skeletal m...
TMPY-04403 NLK/Nemo Like Kinase Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Nemo-like kinase contains 1 protein kinase domain and belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. It also contains a TQE activation loop motif in which autopho...
SARS-CoV-2 Guanine-N7 methyltransferase Protein (His)
TMPJ-01429
Species: SARS-CoV-2
Expression System: E. coli
SARS-CoV-2 Methyltransferase/ME Protein (His)
TMPY-05693
Species: SARS-CoV-2
Expression System: E. coli
GNMT Protein, Human, Recombinant (His)
TMPJ-01118
Species: Human
Expression System: E. coli
TAG-72 Protein, Canine, Recombinant (His)
TMPK-01308
Species: Canine
Expression System: E. coli
ASMT Protein, Human, Recombinant (His & Myc)
TMPH-00878
Species: Human
Expression System: E. coli
PRMT3 Protein, Human, Recombinant (GST)
TMPY-01270
Species: Human
Expression System: E. coli
EEF1AKMT2 Protein, Mouse, Recombinant (His)
TMPH-02635
Species: Mouse
Expression System: E. coli
PRMT6 Protein, Human, Recombinant (His & Flag)
TMPY-01383
Species: Human
Expression System: HEK293 Cells
CARNMT1 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02564
Species: Mouse
Expression System: E. coli
COMT Protein, Human, Recombinant (His)
TMPY-05158
Species: Human
Expression System: Baculovirus Insect Cells
GAMT Protein, Human, Recombinant (His)
TMPJ-01114
Species: Human
Expression System: E. coli
tRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His)
TMPH-00313
Species: Brugia malayi
Expression System: E. coli
HNMT Protein, Human, Recombinant (GST)
TMPY-02340
Species: Human
Expression System: E. coli
DOT1L Protein, Human, Recombinant
TMPY-01708
Species: Human
Expression System: E. coli
METTL1 Protein, Human, Recombinant (His)
TMPY-01661
Species: Human
Expression System: E. coli
EEF2KMT Protein, Human, Recombinant (His)
TMPH-01970
Species: Human
Expression System: E. coli
DNMT2 Protein, Human, Recombinant (GST)
TMPY-01306
Species: Human
Expression System: Baculovirus Insect Cells
Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His)
TMPY-00279
Species: DENV
Expression System: E. coli
ASH2L Protein, Human, Recombinant (His & SUMO)
TMPH-02105
Species: Human
Expression System: E. coli
PR-Set7 Protein, Human, Recombinant
TMPY-01584
Species: Human
Expression System: E. coli
METTL11A Protein, Human, Recombinant
TMPY-01285
Species: Human
Expression System: E. coli
SETD7 Protein, Human, Recombinant (His)
TMPY-01229
Species: Human
Expression System: E. coli
METTL11A Protein, Human, Recombinant (GST)
TMPY-01284
Species: Human
Expression System: E. coli
HEMK2 Protein, Human, Recombinant (His)
TMPY-02420
Species: Human
Expression System: E. coli
MGMT Protein, Human, Recombinant (His)
TMPJ-00872
Species: Human
Expression System: E. coli
METTL25 Protein, Human, Recombinant (His & Myc)
TMPH-01680
Species: Human
Expression System: E. coli
SUV420H2 Protein, Human, Recombinant (His & GST)
TMPY-01657
Species: Human
Expression System: E. coli
METTL7B Protein, Human, Recombinant (His)
TMPH-01682
Species: Human
Expression System: E. coli
ERG Protein, Human, Recombinant (His)
TMPH-02227
Species: Human
Expression System: P. pastoris (Yeast)
INMT Protein, Human, Recombinant (His & SUMO)
TMPH-01529
Species: Human
Expression System: E. coli
SMYD3 Protein, Human, Recombinant (GST)
TMPY-01268
Species: Human
Expression System: Baculovirus Insect Cells
APCDD1 Protein, Human, Recombinant (hFc)
TMPY-03046
Species: Human
Expression System: HEK293 Cells
MAX Protein, Human, Recombinant (His)
TMPJ-01040
Species: Human
Expression System: E. coli
RIOK1 Protein, Human, Recombinant (His & GST)
TMPY-04770
Species: Human
Expression System: Baculovirus Insect Cells
MAX Protein, Human, Recombinant (His & GST)
TMPY-02888
Species: Human
Expression System: Baculovirus Insect Cells
NLK/Nemo Like Kinase Protein, Human, Recombinant (His & GST)
TMPY-04403
Species: Human
Expression System: Baculovirus Insect Cells
カタログ番号 製品名
L1710 Anti-COVID-19 Compound Library

1133 compounds
A unique collection of 1133 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents;