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T63825 |
Antiallergic agent-1
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Antiallergic agent-1, an Src family kinase inhibitor, is a new and valuable lead compound with potential as an anti-allergic agent. |
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T3979 |
Emedastine
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LY188695,Emadine |
Histamine Receptor
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Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its... |
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T6426 |
Buclizine dihydrochloride
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Longifene,Buclina,Buclizine HCl,UCB-4445 |
5-HT Receptor
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AChR
,
Histamine Receptor
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Buclizine dihydrochloride (Buclina) is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine dihydrochloride binds to and ... |
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T2335 |
Ebastine
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Ebastel,LAS-W 090,Ebastin,Kestine,RP64305 |
Histamine Receptor
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Ebastine (Kestine) (trade names Evastin, Kestine, Ebastel, Aleva) is a non-sedating H1 antihistamine. It does not penetrate the blood-brain barrier and thus allows an effective block of the H1 receptor in peripheral tiss... |
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T6488 |
Epinastine hydrochloride
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Alesion,Epinastine HCl,WAL-801CL HCl,Elestat |
5-HT Receptor
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Histamine Receptor
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Epinastine hydrochloride (WAL-801CL HCl) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. |
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T67953 |
Elbanizine
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Others
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Elbanizine showed antiallergic, antiasthmatic, antihistaminic, and spasmolytic activity. |
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T68128 |
Picumast
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Picumast shows antiallergic activity and can be utilized in the treatment of asthma. Picumast may be used in the treatment of therapeutic allergic airway diseases. |
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T14326 |
AS-35
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Others
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T4566 |
Lodoxamide
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Lodoxamidum |
GPR
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Histamine Receptor
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Lodoxamide (Lodoxamidum) is an antiallergic drug acting as a mast-cell stabilizer. It is effective in the treatment of asthma and allergic conjunctivitis. |
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T1425 |
Pemirolast potassium
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BMY 26517,TWT-8152 |
Histamine Receptor
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Pemirolast Potassium is the potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium (TWT-8152) exerts its action by blocking the antigen-mediated calcium ion influx i... |
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T2690 |
Tranilast
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MK 341,SB 252218 |
RAAS
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Prostaglandin Receptor
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Tranilast (SB 252218), an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment of allergic disorders. |
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T1278 |
Astemizole
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Laridal,Histaminos,Paralergin |
Potassium Channel
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Histamine Receptor
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Astemizole (Laridal) is a synthetic piperidinyl-benzimidazol derivative with antiallergic properties, acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to re... |
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T2270 |
Trans-Tranilast
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Tranilast trans- |
RAAS
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Trans-Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It was approved in 1982 for use in Japan and South Korea for bronchial asthma. Indications for keloid and hypertrophic scar were added in 1993.... |
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T9084 |
Cetirizine Impurity B dihydrochloride
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De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride |
Histamine Receptor
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Cetirizine Impurity B dihydrochloride (De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride) is an impurity of Cetirizine dihydrochloride. Cetirizine is a second-generation antihistamine. Cetirizine is a specific, o... |
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T67959 |
Pirodomast
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Thrombin
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Serine Protease
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Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is weakly or ineffectively antagonistic to guinea pig bronchospas... |
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T19839 |
Oxatomide
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Oxatomida |
P2X Receptor
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Calcium Channel
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5-HT Receptor
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Histamine Receptor
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Oxatomide (Oxatomida) is a potent and orally active dual H1 histamine receptor and P2X7 receptor antagonist with antihistamine and antiallergic activity.Oxatomide can be used to block ATP-induced currents in the human P2... |
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T1666 |
Fludrocortisone acetate
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9α-Fluorcortisol acetate,9α-Fludrocortisone acetate,9α-fluorocortisol acetate |
Glucocorticoid Receptor
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Autophagy
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Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of glucocorticoid-respon... |
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T23679 |
AHR-13268D
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AHR 13268D,AHR13268D |
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AHR-13268D is a new agent of antiallergic/antihistaminic. |
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T15666 |
KP136
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AL136 |
Others
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T25413 |
Fenethazine
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RP 3015,Lisergan,Phenetazine,RP-3015,Ethysene |
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Fenethazine is an effective antihistamine used as an antiallergic drug. |
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T25648 |
LC 6
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LC-6,LC6 |
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LC 6 is an orally active antiallergic agent. |
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T26523 |
Abroquinone A
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Abroquinone A, a natural isoflavanquinone, has been shown to block cytosolic phospholipase A(2) and 5-lipoxygenase activation in neutrophils, it may have pharmaceutical potential as an antiallergic agent. |
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T25547 |
Isospaglumate sodium
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Isospaglumate trisodium,Sodium isospaglumate |
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Isospaglumate sodium is the sodium salt of isospaglumate which is an antiallergic agent. |
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T13144 |
Thiazinamium chloride
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Multergan chloride |
Others
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Thiazinamium chloride possesses potent anticholinergic and antiallergic activity and inhibits synthesis of TxB2(IC50 value of 0.2 µM). |
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T63394 |
MrgprX2 antagonist-6
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MrgprX2 antagonist-6 is a potent antiallergic agent with inhibitory effects on mast cell degranulation. |
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T68927 |
AY 25674
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AY 25674 is a drug with antiallergic properties which has been shown to inhibit passive anaphylaxis in rat. |
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T83201 |
Acetyl heptapeptide-4
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Acetyl heptapeptide-4, a bioactive peptide known for its antiallergic properties, is utilized as an ingredient in cosmetics [1]. |
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T71540 |
CI 959
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CI 959 is a novel antiallergic compound which is a potent inhibitor of receptor-mediated histamine release from human basophils. It inhibits thromboxanes. |
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T31191L |
Dagapamil
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Dagapamilum |
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Dagapamil is a calcium-channel blocker. Dagapamil is claimed to have antihypertensive, antiarrhythmic, cardioprotective, antiallergic and platelet aggregation-inhibiting action in animal models. |
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T31191 |
Dagapamil hydrochloride
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Dagapamil hydrochloride is a calcium-channel blocker. Dagapamil hydrochloride is claimed to have antihypertensive, antiarrhythmic, cardioprotective, antiallergic and platelet aggregation-inhibiting action in animal model... |
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T40430 |
Cetirizine Impurity D
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Cetirizine Impurity D is an impurity of Cetirizine. Cetirizine is a second-generation antihistamine that acts as a specific, orally active, and long-acting antagonist of the histamine H1-receptor. Cetirizine exhibits ant... |
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T60289 |
Pemirolast
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Pemirolast is an orally active antiallergic agent. Pemirolast attenuates paclitaxel hypersensitivity reactions through inhibition of the release of sensory neuropeptides, that can be used for bronchial asthma and conjunc... |
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T62421 |
Buclizine
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Buclizine is an orally active antihistamine, antiallergic compound. buclizine is also a strong teratogen in rats and exhibits antitumour effects. |
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T60366 |
Epinastine
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Epinastine (WAL801), a potent, selective, and orally-active antihistamine and mast cell stabilizer, functions as a histamine H1 receptor antagonist. It also inhibits IL-8 release from human eosinophils, showcasing antial... |
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T70904 |
Tylogenin
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Tylogenin, a steroidal aglycone generated by acid hydrolysis from two seasonal glycosides occurring in Tylophora sylvatica, inhibits IgE-induced basophil mediator release for allergic reactions. In the rabbit basophil-de... |
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T73665 |
Bufrolin
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Bufrolin, an analog of Cromoglycate (histamine release inhibitor) and a potent agonist of GPR35, enhances the interaction between β-arrestin-2 and both human GPR35a and rat GPR35. It stabilizes mast cells, exhibiting ant... |
