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Search Results for " IL-5 "

ターゲット

69

阻害剤

8

天然化合物

80

リコンビナントタンパク質

3

ライブラリー

カタログ番号 製品名 別名 ターゲット
T21629 Loxapine Dopamine Receptor , 5-HT Receptor
Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizophrenia. The drug is a member of the dibenzoxazepine class ...
T3133 YM-90709 YM90709,YM 90709 IL Receptor , Interleukin
YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.
T1412 Loxapine succinate Daxolin,Loxapac,Cloxazepin,Loxapine succinate salt Dopamine Receptor , 5-HT Receptor
Loxapine succinate (Loxapac), a D2DR and D4DR inhibitor, is utilized in schizophrenia.
T9962 Mepolizumab SB 240563 IL Receptor
Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5. Mepolizumab can be used in studies about severe eosinophilic asthma and eosinophilic granulomatosis with polyangiitis.
T72598 IL-17 modulator 5
IL-17 modulator 5 is a IL-17 inhibitor, with an IC 50 of 1 nM .
T0117 Suplatast (Tosilate) IPD 1151T,Suplatast tosilate,Suplatast Tosylate IL Receptor , Interleukin
Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.
T9840 Ataquimas Immunology/Inflammation related
Ataquimast inhibits IL-5 secretion along with that of TNF-a, IL-4 and GM-CSF from human cells.
TP2008L Lyn peptide inhibitor acetate Lyn peptide inhibitor acetate(222018-18-0 free base) IL Receptor
Lyn peptide inhibitor acetate is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn peptide inhibitor blocks Lyn activation and inhibits the bind...
T7606 Guanosine 5'-diphosphate disodium salt 5'-GDP-Na2 Endogenous Metabolite
Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway.
T37113 Z62954982 ZINC08010136 Rho
Z62954982 (ZINC08010136) is a selective inhibitor of Rac1, which stunts the growth and branching of neurons.Z62954982 inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary ...
T2061 APY0201 PI3K , Interleukin
APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3, 5)P2.
T3537 GSK583 RIP kinase
GSK583 is a highly effective and specific RIP2 kinase inhibitor (IC50: 5 nM).
T10497 Benralizumab BIW-8405,MEDI-563 Apoptosis , IL Receptor , Interleukin
T6838 FLLL32 Apoptosis , JAK , STAT
FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).
T77675 TNKS-2-IN-1 PARP , Wnt/beta-catenin , Antibiotic
TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.TNKS-2-IN-1 inhibits the releas...
T38361 GSK717 IL Receptor , NOD
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretio...
T5416 T-5224 MMP
T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors.
T4615 Balsalazide sodium hydrate Balsalazide disodium dihydrate,Balsalazide disodium salt dihydrate,Balsalazide disodium STAT , Interleukin
Balsalazide sodium hydrate (Balsalazide disodium) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Balsalazide sodium hydrate is a new 5-aminosalicylic acid (5-ASA) containing prodrug....
T38294 4-Deoxypyridoxine hydrochloride S1P Receptor
4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities. It inhibits transport of pyridoxine , pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells. 4-DPD inhib...
T12706 Reslizumab Sch 55700 IL Receptor
Reslizumab is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma.
TP2008 Lyn peptide inhibitor
Cell-permeable inhibitor of Lyn-dependent effects of the IL-5 receptor. Blocks binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors, blocking Lyn activation. Inhibits IL-5 receptor-mediated eosinoph...
T80577 Varokibart
Varokibart (TEV-53275) is a human IgG4λ antibody that targets interleukin-5 (IL-5) [1].
T70107 Olcorolimus
Olcorolimus inhibits single allergen-induced allergic inflammation such as eosinophilic and lymphocytic infiltration and mRNA expression for interleukin (IL)-4 and IL-5
T28243 Ono 6240 Ono-6240,Ono6240
Ono 6240 is an antagonist of platelet-activating factor. Ono 6240 prevents airway eosinophilia by inhibiting production of IL-2 and IL-5.
T28433 PNU-142731A HCl PNU142731A,PNU 142731A,PNU-142731A
PNU-142731A HCl, a mediator release inhibitor and an IL-5 production inhibitor, is used potentially for the treatment of asthma.
T79024 Androgen receptor-IN-5 Androgen Receptor
Androgen receptor-IN-5 is a potent inhibitor of the androgen receptor with anticancer properties. It additionally suppresses the synthesis of IL-17A, IL-17F, and INF-γ.
T68474 RWJ-58643 HCl
RWJ 58643 is a reversible beta-tryptase and trypsin inhibitor. Low-dose RWJ-58643 (100 microg) and budesonide (200 microg) significantly reduced symptoms, eosinophils and levels of IL-5 following NAC. However, higher dos...
T75806 Lyn peptide inhibitor TFA
Lyn Peptide Inhibitor TFA is a powerful, cell-permeable inhibitor specifically targeting the Lyn-coupled IL-5 receptor signaling pathway, without affecting alternative signaling pathways. It effectively prevents Lyn acti...
T27026 CJ-13,610 CJ 13610,CJ-13610 Lipoxygenase
CJ-13,610 is an orally active and nonredox-type inhibitor of 5-lipoxygenase (5-LOX). CJ-13,610 inhibits the biosynthesis of leukotriene B4 and regulates the expression of IL-6 mRNA in macrophages.
T10210 A-9758 ROR
A-9758 is a RORγ ligand and a selective RORγt inverse agonist (IC50: 5 nM) and exhibits robust potency against IL-17A release. It is effective in suppressing both Th17 differentiation and Th17 effector function. A-9758 s...
T79385 PDE1-IN-5
PDE1-IN-5 (Compound 10c) is a selective PDE1C inhibitor with an IC50 of 15 nM, exhibiting anti-inflammatory properties through the inhibition of iNOS, TNF-α, IL-1α, IL-1β, and IL-6 expression induced by LPS. It has demon...
T62310 CDK8-IN-5
CDK8-IN-5 is a potent inhibitor of CDK8, exhibiting an inhibitory concentration (IC 50) of 72 nM. Demonstrating anti-inflammatory properties, it achieves a 43% enhancement rate of IL-10. This compound holds potential for...
T61621 IMMH001
IMMH001, also known as SYL930, is an orally active compound that exhibits potent selectivity as an agonist for the S1P1 receptor, which is the sphingosine-1-phosphate receptor 1. This compound effectively reduces the lev...
T76869 Lirentelimab
Lirentelimab (AK002), a humanized IgG1 monoclonal antibody, specifically targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). It promotes apoptosis in IL-5-activated eosinophils and suppresses IgE-mediated activation ...
T22172 YS-121
YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-1 ( mPGES-1; IC 50 =3.4 μM) and 5-lipoxygenase ( 5-LOX; IC 50 =6.5 μM). YS121 dose-dependently reduces the production of PGE2 with EC 50 =12 μM in IL-1β-s...
T80959 Trabikibart CSL311
Trabikibart (CSL311), a βc-specific, fully human monoclonal antibody, specifically binds to the cytokine-binding epitope of the human βc receptor with picomolar affinity. It potently inhibits the collective impact of IL-...
T72120 Guanosine 5'-diphosphate sodium GDP sodium
Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate known for activating the adenosine 5'-triphosphate-sensitive K+ channel and serving as a potential iron mobilizer by inhibiting the hepcidin-ferroportin i...
T64232 Agatolimod
Agatolimod (ODN 2006) is a TLR9 agonist, a class B ODN (oligodeoxynucleotide) and the optimal human CpG sequence (sequence: 5'-tcgtcgttttttgtcgttttgtcgtt-3'). agatolimod stimulates NO2 and IL-6 production in HD11 cells. ...
T83670 F1 TFA Tat-IKIP (46-60),Tat-Inhibitor of NF-κB Kinase-interacting Peptide
F1, an anti-inflammatory peptide, incorporates the HIV-1 Tat protein transduction domain linked with a 15-amino acid sequence from residues 46-60 of the inhibitor of NF-κB kinase-interacting peptide (IKIP). It effectivel...
T78762 SIKs-IN-1
SIKs-IN-1 (compound 8h), a pyrimidine-5-carboxamide derivative, functions as an inhibitor of Salt-inducible kinases (SIKs), which play a role in the M1/M2 macrophage polarization linked to inflammation. By inhibiting SIK...
T74911 ODN 24987
ODN 24987, a Guanine-modified inhibitory oligonucleotides (ODN) designed to target TLR9, efficiently suppresses the release of IL-6 and IFN-α, showcasing its potential utility in research on immune disorders. The sequenc...
T37554 Oleyl Anilide
AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleyl analide (OA) is a weak inhibitor of acylCoA:cholesterol acyltransfera...
T75092 STING agonist-24
STING agonist-24 (CF504), a non-nucleotide small-molecule STING agonist, activates STING, leading to increased phosphorylation of STING, TBK1, and IRF3. It elevates levels of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-...
T75094 STING agonist-26
STING agonist-23 (CF508), a non-nucleotide small-molecule STING agonist, activates STING, thereby enhancing the phosphorylation of STING, TBK1, and IRF3. This activation elevates the production of IFN-β, IL-6, CXCL-10, T...
T83773 Prostaglandin E2 Inhibitor 3 PGE2 Inhibitor 3
Prostaglandin E2 (PGE2) inhibitor 3 is a selective inhibitor targeting microsomal prostaglandin E synthase-1 (mPGES-1; IC50 = 0.2 µM), demonstrating greater selectivity for mPGES-1 over COX-1, COX-2, 5-lipoxygenase (5-LO...
T30511 BMS-279700
BMS-279700 is a potent oral activity inhibitor that is part of a new family of aniline 5-azimidazolaquoxaline analogs and has excellent anti-inflammatory activity in vivo, as well as in vitro activity against p56LCK and ...
T63558 IRAK4-IN-21
IRAK4-IN-21 is a selective, orally active, potent IRAK4 inhibitor that acts on IRAK4 (IC50: 5 nM) and TAK1 (IC50: 56 nM). IRAK4-IN-21 exhibits potent inhibition of IL-23 production with an IC50 value of 0.17 μM. can be ...
T36408 Rhein-13C4 Rhein-13C4
Rhein-13C4 is intended for use as an internal standard for the quantification of rhein by GC- or LC-MS. Rhein is an anti-inflammatory anthraquinone found in rhubarb and is the bioactive derivative of its prodrug diacerei...
T75093 STING agonist-25
STING agonist-23 (CF505) is a non-nucleotide, small-molecule compound that stimulates STING, enhancing the phosphorylation of STING, TBK1, and IRF3. It elevates the production of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and ...
T75096 STING agonist-28
STING agonist-23 (CF510) is a non-nucleotide, small-molecule activator of the STING pathway. It initiates the phosphorylation of STING, TBK1, and IRF3, enhancing the production of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and...

Compounds

Loxapine
T21629
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
YM-90709
T3133
Synonym: YM90709,YM 90709
Target: IL Receptor, Interleukin
Loxapine succinate
T1412
Synonym: Daxolin,Loxapac,Cloxazepin,Loxapine succinate salt
Target: Dopamine Receptor, 5-HT Receptor
Mepolizumab
T9962
Synonym: SB 240563
Target: IL Receptor
IL-17 modulator 5
T72598
Synonym:
Target:
Suplatast (Tosilate)
T0117
Synonym: IPD 1151T,Suplatast tosilate,Suplatast Tosylate
Target: IL Receptor, Interleukin
Ataquimas
T9840
Synonym:
Target: Immunology/Inflammation related
Lyn peptide inhibitor acetate
TP2008L
Synonym: Lyn peptide inhibitor acetate(222018-18-0 free base)
Target: IL Receptor
Guanosine 5'-diphosphate disodium salt
T7606
Synonym: 5'-GDP-Na2
Target: Endogenous Metabolite
Z62954982
T37113
Synonym: ZINC08010136
Target: Rho
APY0201
T2061
Synonym:
Target: PI3K, Interleukin
GSK583
T3537
Synonym:
Target: RIP kinase
Benralizumab
T10497
Synonym: BIW-8405,MEDI-563
Target: Apoptosis, IL Receptor, Interleukin
FLLL32
T6838
Synonym:
Target: Apoptosis, JAK, STAT
TNKS-2-IN-1
T77675
Synonym:
Target: PARP, Wnt/beta-catenin, Antibiotic
GSK717
T38361
Synonym:
Target: IL Receptor, NOD
T-5224
T5416
Synonym:
Target: MMP
Balsalazide sodium hydrate
T4615
Synonym: Balsalazide disodium dihydrate,Balsalazide disodium salt dihydrate,Balsalazide disodium
Target: STAT, Interleukin
4-Deoxypyridoxine hydrochloride
T38294
Synonym:
Target: S1P Receptor
Reslizumab
T12706
Synonym: Sch 55700
Target: IL Receptor
Lyn peptide inhibitor
TP2008
Synonym:
Target:
Varokibart
T80577
Synonym:
Target:
Olcorolimus
T70107
Synonym:
Target:
Ono 6240
T28243
Synonym: Ono-6240,Ono6240
Target:
PNU-142731A HCl
T28433
Synonym: PNU142731A,PNU 142731A,PNU-142731A
Target:
Androgen receptor-IN-5
T79024
Synonym:
Target: Androgen Receptor
RWJ-58643 HCl
T68474
Synonym:
Target:
Lyn peptide inhibitor TFA
T75806
Synonym:
Target:
CJ-13,610
T27026
Synonym: CJ 13610,CJ-13610
Target: Lipoxygenase
A-9758
T10210
Synonym:
Target: ROR
PDE1-IN-5
T79385
Synonym:
Target:
CDK8-IN-5
T62310
Synonym:
Target:
IMMH001
T61621
Synonym:
Target:
Lirentelimab
T76869
Synonym:
Target:
YS-121
T22172
Synonym:
Target:
Trabikibart
T80959
Synonym: CSL311
Target:
Guanosine 5'-diphosphate sodium
T72120
Synonym: GDP sodium
Target:
Agatolimod
T64232
Synonym:
Target:
F1 TFA
T83670
Synonym: Tat-IKIP (46-60),Tat-Inhibitor of NF-κB Kinase-interacting Peptide
Target:
SIKs-IN-1
T78762
Synonym:
Target:
ODN 24987
T74911
Synonym:
Target:
Oleyl Anilide
T37554
Synonym:
Target:
STING agonist-24
T75092
Synonym:
Target:
STING agonist-26
T75094
Synonym:
Target:
Prostaglandin E2 Inhibitor 3
T83773
Synonym: PGE2 Inhibitor 3
Target:
BMS-279700
T30511
Synonym:
Target:
IRAK4-IN-21
T63558
Synonym:
Target:
Rhein-13C4
T36408
Synonym: Rhein-13C4
Target:
STING agonist-25
T75093
Synonym:
Target:
STING agonist-28
T75096
Synonym:
Target:
1 2
カタログ番号 製品名 別名 ターゲット
TCS2170 2,5-Dihydroxyacetophenone Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP ERK , NF-κB , Tyrosinase
1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK...
TN1894 Luteolin-4'-O-glucoside Luteolin-4'-glucoside,Luteolin-4-o-glucoside IL Receptor
T7210 Guanosine 5'-diphosphate GDP Endogenous Metabolite
Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.
T6S1538 Neochlorogenic acid trans-5-O-Caffeoylquinic acid,Neochlorogenate,5-O-Caffeoylquinic acid TNF , NF-κB , COX , Antibacterial , Interleukin
Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
T4S0145 Corylifol A Corylinin hCE , STAT , UGT
1. Corylifol A (Corylinin) displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. 2. Corylifol A and Biochanin A can be the potentia...
T4115 Auraptene 7-geranyloxycoumarin MMP , BACE
Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits le...
T2S0843 Negletein 7-O-Methylbaicalein,Baicalein-7-methylether IL Receptor , TNF , NOS , Interleukin
1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n...
T6S1315 Oroxylin A 6-Methoxybaicalein,Baicalein 6-methyl ether Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-03915 IL-5 Protein, Human, Recombinant Human E. coli
Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blo...
TMPY-02554 IL-5 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blo...
TMPY-05576 IL-5 Protein, Human, Recombinant (His) Human HEK293
Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blo...
TMPY-05536 IL-5 Protein, Human, Recombinant (mFc) Human HEK293
Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blo...
TMPK-00021 IL-5 Protein, Human, Recombinant (His & Avi) Human HEK293
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the k...
TMPK-00771 IL-5 Protein, Mouse, Recombinant (His & Avi) Mouse HEK293
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the k...
TMPK-00772 IL-5 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the k...
TMPJ-00020 IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cel...
TMPY-01371 IL-17RA Protein, Human, Recombinant (His) Human HEK293
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret...
TMPJ-00267 IL-5R alpha/CD125 Protein, Human, Recombinant (aa 21-335, His) Human Human Cells
Interleukin-5 Receptor alpha (IL-5Rα, CD125) is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology. Mature human IL-5 Rα consists of a 322 aa extracellular domain (ECD) with a WSxWS motif an...
TMPJ-00266 IL-5R alpha/CD125 Protein, Human, Recombinant (hFc) Human Human Cells
Interleukin-5 Receptor alpha (IL-5Rα, CD125) is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology. Mature human IL-5 Rα consists of a 322 aa extracellular domain (ECD) with a WSxWS motif an...
TMPK-00269 IL-5R alpha/CD125 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Interleukin‑5 Receptor alpha (IL5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5.
TMPK-00268 IL-5R alpha/CD125 Protein, Human, Recombinant (His & Avi) Human HEK293
Interleukin‑5 Receptor alpha (IL5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5.
TMPK-00405 IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated Human HEK293
Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restr...
TMPY-05070 IL-5 Protein, Cynomolgus, Recombinant (His) Cynomolgus Baculovirus-Insect Cells
Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blo...
TMPY-02739 IL-5 Protein, Canine, Recombinant (His) Canine Baculovirus-Insect Cells
Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blo...
TMPH-03118 IL-5 Protein, Pig, Recombinant (His) Sus scrofa (Pig) Yeast
Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
TMPY-06391 IL-17RA Protein, Human, Recombinant (aa 1-320, His & Avi),Biotinylated Human HEK293
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret...
TMPY-05430 IL-17RA Protein, Human, Recombinant (hFc) Human HEK293
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret...
TMPY-05120 IL-17RA Protein, Human, Recombinant (His), Biotinylated Human HEK293
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret...
TMPY-05119 IL-17RA Protein, Human, Recombinant (His & hFc), Biotinylated Human HEK293
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret...
TMPY-06390 IL-17RA Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret...
TMPH-03117 IL-5 Protein, Pig, Recombinant (E. coli, His) Sus scrofa (Pig) E. coli
Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
TMPJ-00981 PTX3 Protein, Mouse, Recombinant (His) Mouse Human Cells
Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory...
TMPJ-00035 IL-4 Protein, Human, Recombinant (His) Human Human Cells
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal ce...
TMPJ-01210 IL-33 Protein, Mouse, Recombinant Mouse E. coli
Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identifi...
TMPY-01650 CD131 Protein, Human, Recombinant (His) Human HEK293
Colony stimulating factor 2 receptor, beta, low-affinity (CSF2RB) also known as CD131 antigen (CD131), cytokine receptor common subunit beta, GM-CSF/IL-3/IL-5 receptor common beta-chain, interleukin 3 receptor/granulocyt...
TMPY-00854 IL-1 alpha/IL-1A Protein, Human, Recombinant Human HEK293
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPY-01738 IL-1 alpha/IL-1A Protein, Mouse, Recombinant Mouse E. coli
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPY-06981 IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli) Human E. coli
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPY-03102 IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-01446 IL-18R beta/IL-18RAP Protein, Human, Recombinant (His) Human HEK293
Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-01410 IL-3R alpha/CD123 Protein, Human, Recombinant (His) Human HEK293
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-05308 CD45 Protein, Human, Recombinant (aa 1-529, His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPJ-00034 IL-4 Protein, Human, Recombinant (hFc) Human Human Cells
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal ce...
TMPK-00242 IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, His & Avi), Biotinylated Human HEK293
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 sub...
TMPJ-01234 IL-36 gamma Protein, Mouse, Recombinant Mouse E. coli
Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in b...
TMPY-04283 CD131 Protein, Rat, Recombinant (hFc) Rat HEK293
Colony stimulating factor 2 receptor, beta, low-affinity (CSF2RB) also known as CD131 antigen (CD131), cytokine receptor common subunit beta, GM-CSF/IL-3/IL-5 receptor common beta-chain, interleukin 3 receptor/granulocyt...
TMPY-02996 IL-17RA Protein, Rat, Recombinant (His) Rat HEK293
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret...
TMPY-03557 IL-17RA Protein, Mouse, Recombinant (hFc) Mouse HEK293
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret...
TMPY-03214 IL-17RA Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret...
TMPY-01849 IL-17RA Protein, Mouse, Recombinant (His) Mouse HEK293
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret...
TMPY-04842 IL-17RA Protein, Rhesus, Recombinant (His) Rhesus HEK293
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret...
TMPY-03910 IL-17RA Protein, Rat, Recombinant (hFc) Rat HEK293
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret...
TMPJ-01283 UGRP1 Protein, Human, Recombinant Human E. coli
Uteroglobin-Related Protein 1 (UGRP1) belongs to the secretoglobin family which has been suggested to play a role in lung inflammation and allergic diseases. UGRP1 is a 17 kDa secreted homodimeric protein that shows amin...
TMPY-05836 IL-1 alpha/IL-1A Protein, Rat, Recombinant Rat E. coli
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPY-04275 IL-36RN/IL-1F5 Protein, Mouse, Recombinant Mouse E. coli
Interleukin-1 family member 5 (IL-1F5), also known as interleukin 36 receptor antagonist (IL36RA), is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-ka...
TMPY-00847 IL-36RN/IL-1F5 Protein, Human, Recombinant Human E. coli
Interleukin-1 family member 5 (IL-1F5), also known as interleukin 36 receptor antagonist (IL36RA), is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-ka...
TMPY-02893 NT5C3A/NT5C3 Protein, Human, Recombinant Human E. coli
NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded prot...
TMPJ-00789 Flagellin Protein, Salmonella Typhimurium, Recombinant Salmonella typhimurium E. coli
Flagellin is the major structural protein monomer of bacterial flagella. Flagellin through binding to its receptor and activation of antigen presenting cells stimulates the innate and adaptive immune responses. Flagellin...
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IL-5 Protein, Human, Recombinant
TMPY-03915
Species: Human
Expression System: E. coli
IL-5 Protein, Mouse, Recombinant (His)
TMPY-02554
Species: Mouse
Expression System: Baculovirus-Insect Cells
IL-5 Protein, Human, Recombinant (His)
TMPY-05576
Species: Human
Expression System: HEK293
IL-5 Protein, Human, Recombinant (mFc)
TMPY-05536
Species: Human
Expression System: HEK293
IL-5 Protein, Human, Recombinant (His & Avi)
TMPK-00021
Species: Human
Expression System: HEK293
IL-5 Protein, Mouse, Recombinant (His & Avi)
TMPK-00771
Species: Mouse
Expression System: HEK293
IL-5 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-00772
Species: Mouse
Expression System: HEK293
IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00020
Species: Human
Expression System: Human Cells
IL-17RA Protein, Human, Recombinant (His)
TMPY-01371
Species: Human
Expression System: HEK293
IL-5R alpha/CD125 Protein, Human, Recombinant (aa 21-335, His)
TMPJ-00267
Species: Human
Expression System: Human Cells
IL-5R alpha/CD125 Protein, Human, Recombinant (hFc)
TMPJ-00266
Species: Human
Expression System: Human Cells
IL-5R alpha/CD125 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00269
Species: Human
Expression System: HEK293
IL-5R alpha/CD125 Protein, Human, Recombinant (His & Avi)
TMPK-00268
Species: Human
Expression System: HEK293
IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated
TMPK-00405
Species: Human
Expression System: HEK293
IL-5 Protein, Cynomolgus, Recombinant (His)
TMPY-05070
Species: Cynomolgus
Expression System: Baculovirus-Insect Cells
IL-5 Protein, Canine, Recombinant (His)
TMPY-02739
Species: Canine
Expression System: Baculovirus-Insect Cells
IL-5 Protein, Pig, Recombinant (His)
TMPH-03118
Species: Sus scrofa (Pig)
Expression System: Yeast
IL-17RA Protein, Human, Recombinant (aa 1-320, His & Avi),Biotinylated
TMPY-06391
Species: Human
Expression System: HEK293
IL-17RA Protein, Human, Recombinant (hFc)
TMPY-05430
Species: Human
Expression System: HEK293
IL-17RA Protein, Human, Recombinant (His), Biotinylated
TMPY-05120
Species: Human
Expression System: HEK293
IL-17RA Protein, Human, Recombinant (His & hFc), Biotinylated
TMPY-05119
Species: Human
Expression System: HEK293
IL-17RA Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06390
Species: Human
Expression System: HEK293
IL-5 Protein, Pig, Recombinant (E. coli, His)
TMPH-03117
Species: Sus scrofa (Pig)
Expression System: E. coli
PTX3 Protein, Mouse, Recombinant (His)
TMPJ-00981
Species: Mouse
Expression System: Human Cells
IL-4 Protein, Human, Recombinant (His)
TMPJ-00035
Species: Human
Expression System: Human Cells
IL-33 Protein, Mouse, Recombinant
TMPJ-01210
Species: Mouse
Expression System: E. coli
CD131 Protein, Human, Recombinant (His)
TMPY-01650
Species: Human
Expression System: HEK293
IL-1 alpha/IL-1A Protein, Human, Recombinant
TMPY-00854
Species: Human
Expression System: HEK293
IL-1 alpha/IL-1A Protein, Mouse, Recombinant
TMPY-01738
Species: Mouse
Expression System: E. coli
IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)
TMPY-06981
Species: Human
Expression System: E. coli
IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (hFc)
TMPY-03102
Species: Rhesus
Expression System: HEK293
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)
TMPY-01446
Species: Human
Expression System: HEK293
IL-3R alpha/CD123 Protein, Human, Recombinant (His)
TMPY-01410
Species: Human
Expression System: HEK293
CD45 Protein, Human, Recombinant (aa 1-529, His)
TMPY-05308
Species: Human
Expression System: HEK293
IL-4 Protein, Human, Recombinant (hFc)
TMPJ-00034
Species: Human
Expression System: Human Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, His & Avi), Biotinylated
TMPK-00242
Species: Human
Expression System: HEK293
IL-36 gamma Protein, Mouse, Recombinant
TMPJ-01234
Species: Mouse
Expression System: E. coli
CD131 Protein, Rat, Recombinant (hFc)
TMPY-04283
Species: Rat
Expression System: HEK293
IL-17RA Protein, Rat, Recombinant (His)
TMPY-02996
Species: Rat
Expression System: HEK293
IL-17RA Protein, Mouse, Recombinant (hFc)
TMPY-03557
Species: Mouse
Expression System: HEK293
IL-17RA Protein, Rhesus, Recombinant (hFc)
TMPY-03214
Species: Rhesus
Expression System: HEK293
IL-17RA Protein, Mouse, Recombinant (His)
TMPY-01849
Species: Mouse
Expression System: HEK293
IL-17RA Protein, Rhesus, Recombinant (His)
TMPY-04842
Species: Rhesus
Expression System: HEK293
IL-17RA Protein, Rat, Recombinant (hFc)
TMPY-03910
Species: Rat
Expression System: HEK293
UGRP1 Protein, Human, Recombinant
TMPJ-01283
Species: Human
Expression System: E. coli
IL-1 alpha/IL-1A Protein, Rat, Recombinant
TMPY-05836
Species: Rat
Expression System: E. coli
IL-36RN/IL-1F5 Protein, Mouse, Recombinant
TMPY-04275
Species: Mouse
Expression System: E. coli
IL-36RN/IL-1F5 Protein, Human, Recombinant
TMPY-00847
Species: Human
Expression System: E. coli
NT5C3A/NT5C3 Protein, Human, Recombinant
TMPY-02893
Species: Human
Expression System: E. coli
Flagellin Protein, Salmonella Typhimurium, Recombinant
TMPJ-00789
Species: Salmonella typhimurium
Expression System: E. coli
カタログ番号 製品名
L8720 Pyroptosis Compound Library

1077 compounds
1077 types of active small molecules associated with pyroptosis for high-throughput and high-content screening.
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740 compounds
A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;
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A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;