64
27
52
5
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T21632 | Myoseverin | Others , Microtubule Associated | |
Myoseverin, an inducer of the reversible fission of multinucleated myotubes into mononucleated fragments, affecting the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and str... | |||
T8575 | ENFENAMIC ACID | Platelet aggregation | |
Enfenamic acid is a platelet aggregation inhibitor and with antirheumatic. | |||
T7469 | Alendronic Acid | alendronate | Others |
Alendronic Acid (alendronate) is a nonhormonal medication used for osteoporosis, osteogenesis imperfecta, and several other bone diseases. | |||
T16850 | SB-265610 | GSK-CXCR2 | CXCR |
SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and... | |||
T21653 | 1,4-DPCA | HIF/HIF Prolyl-Hydroxylase | |
1,4-DPCA is an inhibitor of prolyl-hydroxylase with an IC50 of 2.4 µM for collagen hydroxylation in human foreskin fibroblasts and 60 μM for factor inhibiting HIF (FIH). | |||
T4478 | CID 16020046 | C390-0219 | Cannabinoid Receptor |
CID 16020046 (C390-0219) is a selective GPR55 antagonist, inhibiting GPR55 constitutive activity with IC50 of 0.15 μM in yeast. | |||
T15259 | Evatanepag | CP-533536 free acid | Prostaglandin Receptor |
Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered l... | |||
T2206 | Quadrol | N,N,N′,N′-Tetrakis(2-hydroxypropyl)ethylenediamine,EDTP,Edetol | Others |
Quadrol (EDTP) is an immunostimulant, accelerated wound healing. | |||
T35074 | VRT-325 | CFcor 325,VRT-534,CFcor325,VRT 325,VRT325,CF-106951,CFcor-325 | Others |
VRT-325 can repair folding defects by promoting dimerization of the two NBDs or by promoting folding of the TMD.VRT-325 accelerates the healing rate of CF cell monolayers. | |||
T19841 | Tribenoside | Glyvenol,Glyvenal,Ba 2140,BG-356,Glivenol,TBGF | Others |
Tribenoside (BG-356) is a vasoprotectant with mild anti-inflammatory, analgesic, and wound healing properties. | |||
T40570L | LKKTETQ acetate | LKKTETQ acetate (476014-70-7 Free base) | Others |
LKKTETQ acetate is the active site in the protein thymosin β4 responsible for wound healing, actin binding and cell migration. | |||
T13823 | Polyvinylpyrrolidone | PVP,Povidone,Polyvidone | Others |
Polyvinylpyrrolidone (Polyvidone) used in human and veterinary medicine as an effective wound healing accelerator. | |||
T8807 | Benzydamine | Others | |
Benzydamine is a benzyl-indazole having analgesic, antipyretic, and anti-inflammatory effects. Benzydamine is used to reduce post-surgical and post-traumatic pain and edema and to promote healing. | |||
T41206 | Poly Vinyl Alcohol | Polyvinyl alcohol | Others |
Poly Vinyl Alcohol (Polyvinyl alcohol) is a water-soluble, biodegradable, wound-healing polymer used in a wide range of biomedical applications.Poly Vinyl Alcohol is commonly used in the manufacture of medical excipients... | |||
T36033 | DETA NONOate | NOC-18,Diethylamine NONOate | NO Synthase |
DETA NONOate (NOC 18) is an exogenous nitric oxide (NO) donor with vasodilatory and antidepressant activity.DETA NONOate can be used to activate inward currents in neurons, which may accelerate the healing of MRSA-infect... | |||
T74048 | PAPA NONOate | Endogenous Metabolite , NO Synthase | |
PAPA NONOate is a pH-regulated NO donor.PAPA NONOate has potential antitumor activity and can be used to study diabetic wound healing disorders. | |||
T7116 | Sodium gualenate | Guaiazulenesulfonate sodium | Others |
Sodium gualenate (Guaiazulenesulfonate sodium) (Guaiazulenesulfonate sodium), a hydrophilic derivative of guaiazulene (GA), is an unstable compound. It has anti-inflammatory and wound-healing effects. | |||
TP2319 | Thymosin β4 acetate(75591-33-4 free base) | Autophagy | |
Thymosin β4 (Tβ4) is a thymic hormone with multiple and different intracellular and extracellular activities affecting wound healing, inflammation, fibrosis and tissue regeneration. | |||
T31615 | Elsibucol | AGI-1096,UNII-O7T92N1Y8T,AGI 1096 | Antioxidant |
Elsibucol (AGI 1096) is a VCAM1 inhibitor for the study of organ transplant rejection.Elsibucol is a metabolically stable propanol derivative with antioxidant, anti-inflammatory and anti-proliferative properties. It lowe... | |||
T21550 | Blebbistatin | (±)-Blebbistatin | ATPase , Myosin |
Blebbistatin ((±)-Blebbistatin) is a selective non-muscle myosin II (NMII) inhibitor. It promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing. Furthermore it preserves cell jun... | |||
T32613 | LCB 03-0110 dihydrochloride | Src | |
LCB 03-0110 Dihydrochloride is a potent inhibitor of the c-Src kinase (IC50 = 1.3 nM) and tyrosine kinases in the BTK and SYK family, as well as in the DDR2 family. It inhibits LPS-induced activation of macrophages and T... | |||
T4425 | JK-P3 | VEGFR | |
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube format... | |||
T31195 | Dalcotidine | KU 1257,KU-1257 | Histamine Receptor |
Dalcotidine (KU 1257) is a novel histamine H2 receptor antagonist with histamine H9 receptor antagonistic activity and antisecretory effects.The Ki value for binding to guinea pig cerebral cortex was 0.040 The KB value f... | |||
T41231 | GP 1a | Cannabinoid Receptor , PERK , Arrestin | |
GP 1a is a potent agonist of cannabinoid receptor 2 (CB2) (EC50=7.1), as shown in cAMP, GTPγS and β-arrestin recruitment assays. GP 1a is approximately 30-fold more selective for CB2 receptors than CB1 receptors and incr... | |||
T29547 | Acemannan | Acemannanan | |
Acemannan can produce cell proliferation and skin wound healing through AKT/mTOR signaling pathway. | |||
T34087 | Plaunotol | Kelnac,Plaunotolum | |
Plaunotol is a gastric protective agent that increases prostaglandins in the gastric mucosa and accelerates ulcer healing. | |||
T34693 | Sphingosine phosphorylcholine | ||
Sphingosine phosphorylcholine is a wound healing agent. | |||
T25309 | Dermabond | Liquid Bandage,2-Octyl 2-cyanoacrylate,RiteLok CON 895 | |
Dermabond is an antibacterial compound that has been used in basic science research for wound healing. | |||
T33710 | Nocloprost | ||
Nocloprost is a prostaglandin E2 analog with local gastroprotective and ulcer-healing activity. | |||
T28146 | ND-336 | ND336,ND-336 hydrochloride,ND 336 | |
ND-336 is a highly selective inhibitor ofMMP-2, MMP-9 and MMP-14. ND-336 accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound. | |||
T40570 | LKKTETQ | ||
LKKTETQ, a peptide segment within thymosin β 4, constitutes the protein's active site responsible for actin binding, cell migration, and wound healing. | |||
TP2362 | Acetyl decapeptide-3 | Rejuline,Ac-tyr-arg-ser-arg-lys-tyr-thr-ser-trp-tyr-NH2 | |
Acetyl decapeptide-3 is a peptide that can stimulate collagen and elastin to increase skin elasticity and increase cell growth and improve healing and repair. | |||
T30107 | Apratyramide | ||
Apratyramide is a marine-derived peptidic stimulator of VEGF-A and other growth factors with potential application in wound healing. | |||
T26554 | Aclerastide | DSC-127,DSC 127,NorLeu-3-A(1-7),DSC127,NorLeu-3A(1-7) | |
Aclerastide is an angiotensin receptor agonist. Administration of Aclerastide reduced fibrosis and scarring in the healing wounds. This action was more pronounced with longer administration of the peptide after injury. T... | |||
T68206 | Arbortristoside A | ||
Arbortristoside A is an anti-inflammatory and antinociceptive. This activity may be due to the inhibiting effect of prostaglandin, histamine and serotonin. Arbortristoside A has also been shown to act on ulcerations and ... | |||
T69755 | Evatanepag sodium | ||
Evatanepag, also known as CP-533536, is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation. CP-533536 demonstrated the ability to heal fractures when administered locally as a sin... | |||
T21185 | CEP03 | CEP 03,CEP-03 | |
CEP03 enhances EC/EPC proliferation, tubelike formation, and wound-healing efficiency, leading to promote angiogenesis and significantly improve blood flow perfusion recovery in the ischemic hind limbs of mice. | |||
T71801 | Arbaprostil | ||
Arbaprostil is a synthetic prostaglandin E analog that protects gastric mucosa, prevents ulceration, and promotes healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inh... | |||
T34653 | SK1071 | ||
SK1071 is a novel migrastatin analogs, which demonstrated improved performance over migrastatin, with nanomolar IC50 values in chamber cell migration assays with tumor cells and human umbilical vein endothelial cells (HU... | |||
T14139 | Aganepag | AGN 210937 | Prostaglandin Receptor |
Aganepag, a potent Prostanoid EP2 receptor agonist, exhibits remarkable selectivity with an EC50 of 0.19 nM, demonstrating no activity at the EP4 receptor. Its applications are primarily in the fields of wound healing, s... | |||
T82358 | G-{d-Arg}-GDSPASSK | ||
G-{d-Arg}-GDSPASSK is a polypeptide that inhibits cell adhesion, facilitates wound healing, and promotes tissue repair [1]. | |||
T41189 | AY 254 | ||
AY 254 is a potent PAR2 biased agonist. Selectively activates ERK1/2 signaling (EC50= 2 nM for ERK1/2 phosphorylation versus 80 nM for Ca2+release). Reduces cytoKi ne-induced caspase 3/8 activation, promotes scratch-woun... | |||
T15642 | KAG-308 | Prostaglandin Receptor | |
KAG-308 is an effective selective and orally active agonist of the EP4 receptor (Ki: 2.57 nM and EC50: 17 nM for human EP4 receptor), more selective over EP1, EP2, EP3, and IP receptor. KAG-308 suppresses colitis and pro... | |||
T61106 | GRP78-IN-1 | ||
GRP78-IN-1 displays interactions with specific residues on the GRP78 protein with a binding energy of -8.07 kcal/mol. This compound possesses potent cytotoxic and anti-proliferative effects on cancer cells, particularly ... | |||
T81404 | Prezatide copper | Bisprezatide copper,PC 1020,Iamin | |
Prezatide copper (also known as Bisprezatide copper or Iamin) serves as an inhibitor of hair loss and is recognized for its multiple wound-healing properties as a human growth factor [1]. | |||
T70826 | PF-03671148 | ||
PF-03671148 is a potent ALK inhibitor. PF-03671148 inhibits the expression of fibrotic genes and protein markers both in vitro in human fibroblasts and in vivo in a rat wound repair model. Wound healing is not inhibited ... | |||
T78018 | Plasminogen | ||
Plasminogen is a zymogen secreted as a precursor protein that, when cleaved by urokinase plasminogen activator (uPA) or tissue plasminogen activator (tPA), is converted into plasmin. Plasmin is a protease with broad spec... | |||
T81330 | Q-Peptide | ||
Q-Peptide, an angiopoietin-1 derived peptide (QHREDGS), enhances keratinocyte migration, thereby facilitating wound healing in a diabetic mouse model, and accelerates wound closure [1]. | |||
T75858 | LL-37, human acetate | ||
LL-37, human acetate, is a 37-residue amphipathic peptide derived from cathelicidin, known for its broad-spectrum antimicrobial properties. This compound not only plays a crucial role in safeguarding the cornea against i... | |||
T81074 | Sucrose octasulfate sodium | ||
Sucrose octasulfate, a constituent of sulfoaluminum, promotes the release of somatostatin-like immunoreactivity (SLI) through direct interaction with D cells within the gastric mucosa, thereby exerting its ulcer-healing ... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T3855 | Tracheloside | Estrogen Receptor/ERR , Phosphorylase | |
Tracheloside significantly decreases the activity of alkaline phosphatase (IC50: 0.31 μg/ml), a level of inhibition comparable to that of tamoxifen (IC50: 0.43 μg/ml). | |||
T3881 | Vaccarin | Integrin , Akt , PERK , AMPK | |
Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, glycosylation and deglycosylation. | |||
T5S1982 | Periplocin | Periplocoside | Apoptosis , Others |
1. Periplocin (Periplocoside) has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. Periplocin is used for treatment of rheumato... | |||
TN1686 | Ginsenoside Rg4 | Antibacterial | |
Ginsenoside Rg4 is a natural product | |||
T2827 | Asiatic acid | Asiantic acid,Dammarolic acid | Apoptosis , p38 MAPK , Parasite |
Asiatic acid (Dammarolic acid) is the aglycone of asiaticoside used in wound healing with antioxidant, anti-inflammatory, and neuroprotective properties. | |||
TN3016 | 4',6,7-Trimethoxyisoflavone | MMP | |
4',6,7-Trimethoxyisoflavone promotes wound healing through NOX2 induction, which leads to collective migration and MMP activation. | |||
TN2077 | (+/-)-Pinocembrin | NSC 43318,(±)-5,7-Dihydroxyflavanone | GPR , Others |
(+/-)-Pinocembrin (NSC-43318), a natural product from axillary pines, is a GPR120 ligand that promotes wound healing in the HaCaT cell line. | |||
T13768 | (+)-Medicarpin | Estrogen/progestogen Receptor | |
(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from multiple medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium flo... | |||
T3488 | Tectorigenin | 4',5,7-Trihydroxy-6-methoxyisoflavone,Tectorigenine | Apoptosis |
Tectorigenin (4',5,7-Trihydroxy-6-methoxyisoflavone) is an O-methylated isoflavone. Tectorigenin Promotes Osteoblast Differentiation and in vivo Bone Healing, but Suppresses Osteoclast Differentiation and in vivo Bone Re... | |||
TN1079 | Deoxyelephantopin | NF-κB | |
Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling | |||
T1125 | Shikonin | NSC 252844,Isoarnebin 4,(+)-Shikonin,Alkanna Red,C.I. 75535,Anchusa acid | TNF , NF-κB , Chloride channel , HIV Protease , PKM |
Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. Shikonin exhibits antitumor, anti-inflammatory and wound healing activities. | |||
T4454 | Traumatic Acid | Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,Trans-2-Dodecenedioic Acid | Antioxidant |
Traumatic Acid (Dodec-2-Enedioic Acid) is a product of the hydroperoxide lyase pathway in plants. Potential as a wound healing agent that stimulates cell division near a wound site to form a protective callus. | |||
TN7082 | Demethyldaphnoretin-7-O-glucoside | Others | |
Demethyldaphnoretin-7-O-glucoside is a natural product that is isolated from Daphne oleoides Schreber subsp. kurdica (DOK). In Turkish traditional medicine, the aerial parts of DOK have been used to treat malaria, rheuma... | |||
TN1641 | (-)-Fenchone | Others , Antioxidant , Antifungal | |
(-)-Fenchone is a bicyclic monoterpenoid widely distributed in plants and can be extracted from Foeniculum vulgare and Peumus boldus. (-)-Fenchone has a wide range of biological activities including antioxidant, wound he... | |||
TN1132 | Procyanidin A2 | IL Receptor , TNF , transporter , Antibacterial | |
Procyanidin A2 is a potential precursor of 5-(3',4'-dihydroxyphenyl)-γ-valerolactone, exhibits antioxidant, anti-inflammary, anti-hyperglycemia, and anti-type 2 diabetes activities. Procyanidin A2 demonstrates liver cell... | |||
T3O2749 | L-Leucine | (S)-Leucine,Leu | mTOR |
L-Leucine ((S)-Leucine) is one of nine essential amino acids in humans (provided by food), L-Leucine is important for protein synthesis and many metabolic functions. L-Leucine contributes to regulation of blood-sugar lev... | |||
T5S2347 | Deoxyshikonin | Arnebin 7 | Others , HIF/HIF Prolyl-Hydroxylase , Antibacterial |
1. Deoxyshikonin (Arnebin 7) may be a new drug candidate for wound healing and treatment of lymphatic diseases. 2. Deoxyshikonin enhances the ability of human dermal lymphatic microvascular endothelial cells (HMVEC-dLy) ... | |||
TN6926 | Paeonoside | Others | |
Paeonoside, found in P. suffruticosa, is biologically active and can promote wound healing and migration during osteoblast differentiation. Paeonoside has certain antidiabetic activity and may prevent sepsis and death fr... | |||
TN6872 | Trypsin | Protease-activated Receptor | |
Trypsin is a serine protease that can be isolated from fish to hydrolyze lysine or arginine carboxy-side proteins. With the anti-inflammatory activity, Trypsin could induce the cell membrane fusion of PDCoV-infected cell... | |||
T1437 | D-Panthenol | D-Pantothenyl alcohol,Ilopan,Dexpanthenol,Pantothenol | Endogenous Metabolite |
D-Panthenol (D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent. D-Panthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis... | |||
TN6495 | 3,4-O-dimethylcedrusin | ||
3′,4-O-Dimethylcedrusin can improve wound healing in vivo by stimulating the formation of fibroblasts and collagen. | |||
T13559 | Astragaloside VI | EGFR | |
TN5044 | Specioside | Others | |
Specioside has antioxidant, analgesic, anti-dyspeptic, astringent, liver stimulating and wound healing activities. It ameliorates oxidative stress and promotes longevity in Caenorhabditis elegans. | |||
T8001 | Aloe vera | Others | |
Aloe vera is a natural product that has useful effects on wounds especially cutaneous wounds healing. | |||
T81322 | Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside | ||
Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside, isolated from the aerial parts of the fern Ophioglossum vulgatum L., exhibits wound healing activity [1]. | |||
T40611 | (E)-Dehydrodiconiferyl alcohol | ||
(E)-Dehydrodiconiferyl alcohol is a potent dual inhibitor of hCA IX and hCA XII, effectively impeding the catalytic activity of both carbonic anhydrase isoforms. Additionally, (E)-Dehydrodiconiferyl alcohol exerts inhibi... | |||
T78490 | Polygalacturonic acid | Galacturonic acid polymer | |
Polygalacturonic acid (Galacturonic acid polymer), a transparent colloid, constitutes a significant portion of the cell wall. It is employed in the synthesis of silver nanoparticles (AgNPs), serving both as an antioxidan... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-02185 | Coagulation factor XIII B/F13B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ... | |||
TMPJ-00562 | PDGF-BB Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P... | |||
TMPJ-00037 | FGF-2 Protein, Mouse, Recombinant | Mouse | E. coli |
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mo... | |||
TMPY-01061 | FGF-10 Protein, Human, Recombinant | Human | E. coli |
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes... | |||
TMPK-00367 | MMP-9 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demon... | |||
TMPK-00503 | MMP-9 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demon... | |||
TMPH-02830 | PLET1 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. | |||
TMPH-02594 | MMP-13 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the hig... | |||
TMPH-02243 | TFF3 Protein, Human, Recombinant (GST) | Human | E. coli |
Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen). | |||
TMPH-00502 | TFF3 Protein, Canine, Recombinant (His & Myc) | Canine | E. coli |
Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen). | |||
TMPH-02831 | PLET1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. | |||
TMPK-00368 | MMP-9 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demon... | |||
TMPH-01865 | PLET1 Protein, Human, Recombinant (His) | Human | E. coli |
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. PLET1... | |||
TMPK-01334 | EMMPRIN/CD147 Protein, Canine, Recombinant (His) | Canine | HEK293 Cells |
CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiolo... | |||
TMPJ-01173 | TFF3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Trefoil factors (TFF) are secretory products of mucin producing cells. They play a key role in the maintenance of the surface integrity of oral mucosa and enhance healing of the gastrointestinal mucosa by a process calle... | |||
TMPH-01297 | DDR1 Protein, Human, Recombinant (aa 21-417, His) | Human | HEK293 Cells |
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival ... | |||
TMPH-01866 | PLET1 Protein, Human, Recombinant (His & Myc) | Human | Baculovirus Insect Cells |
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. PLET1... | |||
TMPH-01974 | Prothrombin Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wo... | |||
TMPH-03599 | Streptopain Protein, S. pyogenes, Recombinant (His & SUMO) | Streptococcus pyogenes | E. coli |
Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelia... | |||
TMPK-00259 | Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differen... | |||
TMPJ-00271 | SMAD3 Protein, Human, Recombinant (His & Flag) | Human | E. coli |
Mothers against decapentaplegic homolog 3(SMAD3) is a cytoplasm protein which belongs to the dwarfin/SMAD family. Smad proteins undergo rapid nuclear translocation upon stimulation by transforming growth factor and in so... | |||
TMPK-00850 | MFGE8 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
MFGE8 (Milk Fat Globule EGF And Factor V/VIII Domain Containing) is a Protein Coding gene. Diseases associated with MFGE8 include Anal Paget's Disease and Topographical Agnosia. Among its related pathways are Activated P... | |||
TMPH-03598 | Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO) | Streptococcus pyogenes | E. coli |
Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelia... | |||
TMPK-00258 | Latent TGF beta 3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differen... | |||
TMPY-04801 | Fibromodulin Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Fibromodulin (FMOD), an ECM small leucine-rich proteoglycan (SLRP), was reported to promote angiogenesis not only during wound healing, but also in optical and cutaneous angiogenesis-dependent diseases. The autocrine FM... | |||
TMPH-02835 | PDGFD Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role ... | |||
TMPK-01044 | VEGFC Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet... | |||
TMPK-01043 | VEGFC Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet... | |||
TMPK-00954 | Hyaluronidase 2/HYAL2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Hyaluronidases, a family of enzymes that are able to degrade hyaluronic acid (HA), are employed in medicine to increase drug diffusion and reverse the effects of HA filler injections. Hyaluronidases are able to dissolve ... | |||
TMPK-00725 | Hyaluronidase 2/HYAL2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Hyaluronidases, a family of enzymes that are able to degrade hyaluronic acid (HA), are employed in medicine to increase drug diffusion and reverse the effects of HA filler injections. Hyaluronidases are able to dissolve ... | |||
TMPJ-00771 | TGF beta 1 Protein, Mouse/Rat, Recombinant | Mouse,Rat | HEK293 Cells |
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differen... | |||
TMPY-00371 | STC1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Stanniocalcin-1 (STC1) is a paracrine factor associated with inflammation and carcinogenesis. STC1 is a secreted glycoprotein hormone and involved in various types of human malignancies. Stanniocalcin-1 (STC1), which has... | |||
TMPJ-01433 | Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated | Human | E. coli |
Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components ... | |||
TMPY-01484 | THSD1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein that contains one TSP type-1 domain. THSD1 is ... | |||
TMPJ-00304 | ALK-1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10. ALK1 signaling is necessary for angi... | |||
TMPY-03419 | SMAD3 Protein, Human, Mouse, Rat, Recombinant (His & GST) | Human,Mouse,Rat | Baculovirus Insect Cells |
SMAD3 belongs to the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD3 is... | |||
TMPY-02838 | FGFBP3 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
FGFBP3 is a member of the fibroblast growth factor-binding protein family. Members of this family binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. Fibroblast growth factors (FGFs) are impo... | |||
TMPJ-01177 | NOV/CCN3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor... | |||
TMPJ-00534 | HFcgR4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Fcgr4, also known as CD16-2, is one of the receptors for Fc region of IgG which involve in immune responses. Fcgr4 mainly functions in cellular response to lipopolysaccharide, NK T cell proliferation, regulation of senso... | |||
TMPY-02174 | FABP5 Protein, Human, Recombinant | Human | E. coli |
Fatty acid-binding protein, also known as Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, E-FABP and FABP5, is a cytoplasm protein whic... | |||
TMPY-04828 | TFF3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Trefoil factor family (TFF) peptides are involved in the maintenance of epithelial integrity and epithelial restitution. Trefoil factor-3 (TFF3) is an estrogen-regulated gene associated with prognosis in different types ... | |||
TMPJ-00535 | F13A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, ... | |||
TMPY-01680 | Lumican Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Lumican, a prototypic leucine-rich proteoglycan with keratan sulfate side chains, is a major component of the cornea, dermal, and muscle connective tissues. In these bifunctional molecules, the protein moiety binds colla... | |||
TMPY-01190 | INHBB Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two ... | |||
TMPY-02760 | CALML3 Protein, Human, Recombinant (His) | Human | E. coli |
Calmodulin-like protein 3 (CALML3) is similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinity, to cellular substrates. Calmodulin-like protein 3 (CALML3) is a ... | |||
TMPY-01846 | Activin A Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two ... | |||
TMPY-04534 | GDF-8 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
GDF-8 / Myostatin / MSTN is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to pro... | |||
TMPY-02246 | HB-EGF Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
Heparin-binding EGF-like growth factor (HBEGF), a member of the EGF family of growth factors, exerts its biological activity through activation of the EGFR and other ErbB receptors. Soluble mature HBEGF is proteolyticall... | |||
TMPY-02574 | Chymase 1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
The STR polymorphism in the CMA1 gene is associated with asthma and that this association is even stronger with atopic asthma. CMA1 and IL-4 in atopic asthma and for IL-4 in atopy in general. The local angiotensin II sys... | |||
TMPH-02524 | Arginase-1/ARG1 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell ... | |||
------------------------ More ------------------------ |
カタログ番号 | 製品名 | ||
---|---|---|---|
L9810 | Anti-Fibrosis Compound Library | 1180 compounds | |
A unique collection of 1180 potential anti-fibrosis compounds, can be used in HTS and HCS; | |||
L6300 | Food as Medicine Compound Library | 1290 compounds | |
A unique collection of 1290 compounds from food as medicine for high throughput and high content screening; | |||
L4800 | Angiogenesis related Compound Library | 1353 compounds | |
A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS); | |||
L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; | |||
L8500 | HIF-1 Signaling Pathway Compound Library | 1336 compounds | |
A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies; |