58
40
15
2
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T6495 | EUK-134 | EUK 134 | Beta Amyloid |
EUK-134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril. | |||
T33602 | NBD-Pen | NBDPen,LipiRADICAL Green,NBD Pen,FDV-0042,Funakoshi | |
NBD-Pen (LipiRADICAL Green) is a fluorescent probe that detects lipid free radicals in living cells. | |||
T22739 | DMPO | 5,5-Dimethyl-1-pyrroline N-oxide | Others |
DMPO (5,5-Dimethyl-1-pyrroline N-oxide) is a kind of water-soluble nitric oxide spin trap, which allows the measurement of oxygen-centered free radicals in biological systems at room temperature using electron spin reson... | |||
T19023 | Lucigenin | NSC-151912,L-6868 | Others |
Lucigenin (NSC-151912) (L-6868) is a chemiluminescent probe used to indicate the presence of endogenously generated superoxide anion radicals in cells. | |||
TP2321L | H-PRO-HIS-CYS-LYS-ARG-MET-OH acetate | H-PRO-HIS-CYS-LYS-ARG-MET-OH acetate(159147-88-3 free base) | Others |
H-PRO-HIS-CYS-LYS-ARG-MET-OH acetate acts as antioxidant by reacting with active oxygen species such as superoxide and hydroxyl radicals. | |||
T0701 | Broxyquinoline | Dibromohydroxyquinoline,5,7-Dibromo-8-hydroxyquinoline | Antibiotic , Parasite |
Broxyquinoline (5,7-Dibromo-8-hydroxyquinoline) is an antiprotozoal agent, and it can release oxygen free radicals from the water in mucous membranes. | |||
T20509 | Lophine | 2,4,5-Triphenylimidazole,NSC 62790,NSC-62790,NSC62790 | Others |
Lophine (NSC-62790) can be used in the synthesis of protein kinase inhibitors, calcium antagonists, strong Chemicalbook cardiac agents, and antitumor drugs. Lophine derivatives act as in vitro chemiluminescent activators... | |||
T64781 | Biotin-4-aminophenol | ||
Biotin-4-aminophenol (BP) is a selective and potent biotin-phenol analog that works by generating free radicals and binding to tyrosine residues in proteins. | |||
T19428 | Mito-TEMPO | Reactive Oxygen Species , Mitochondrial Metabolism | |
Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO scavenges superoxide and alkyl radicals and prevents mitochondrial oxidation, necrosis and apoptosis. | |||
T21233 | Dihydrolipoic acid | Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid | Antioxidant |
Dihydrolipoic acid (USAF XR-12), a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydr... | |||
T0402 | Octocrylene | Octocrilene | Others |
Octocrylene (Octocrilene) is used as an ingredient in sunscreens and cosmetics. This organic compound can penetrate into the skin where it acts as a photosensitizer. This results in an increased production of free radica... | |||
T63750 | α-Amylase-IN-1 | Antioxidant , Amylase | |
α-Amylase-IN-1 is an α-Amylase inhibitor (IC50: 0.5509 μM). α-Amylase-IN-1 has antioxidant activity with an IC50 value of 53.49 μM for scavenging of DPPH free radicals, and can be used in the study of diabetes and oxidat... | |||
T0223 | Tetrahydroxyquinone | 4-benzoquinone,Tetrahydroxybenzoquinone,Tetrahydroxy-1,Tetrahydroxy-1,4-benzoquinone,Tetroquinone | Apoptosis , Antioxidant , Reactive Oxygen Species |
Tetrahydroxyquinone (Tetroquinone) is a molecule best known as a primitive anticataract drug, is also a highly redox active molecule that can take part in a redox cycle with semiquinone radicals, leading to the formation... | |||
T1229 | Erdosteine | RV 144,KW-9144 | NF-κB , Antibacterial , Adenosine deaminase |
Erdosteine (RV 144) is a homocysteine-derived thiol derivative with mucolytic and free radical scavenging properties. Erdosteine and its metabolites modulate mucus production and viscosity, by which facilitating mucocili... | |||
T3647 | HTHQ | HX 1171,HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone),1-O-hexyl-2,3,5-trimethylhydroquinone | Reactive Oxygen Species |
HTHQ (HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone)), a hydroquinone monoalkyl ether, is an effective anti-oxidative agent. HTHQ is a potent anti-lipid-peroxidative compound and its antioxidation activity to be extremely e... | |||
T1488 | Procarbazine hydrochloride | NSC-77213 HCl,Procarbazine HCl | DNA Alkylator/Crosslinker , DNA/RNA Synthesis |
Procarbazine hydrochloride (NSC-77213 HCl) is the hydrochloride salt of a methylhydrazine derivative with antineoplastic and mutagenic activities. Although the exact mode of cytotoxicity has not been elucidated, procarba... | |||
T0893 | Tinidazole | CP12574 | Antibacterial , Antibiotic |
Tinidazole (CP12574)a is a 5-nitroimidazole derivative with the antiprotozoal property. Although the mechanism of action has not been fully elucidated, it has been suggested that tinidazole is metabolized and yields nitr... | |||
T1562 | Rebamipide | Proamipide,OPC12759 | Free radical scavengers , COX , Prostaglandin Receptor |
Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis ... | |||
T0825 | Ebselen | SPI-1005,PZ-51,CCG-39161 | Phosphatase , Virus Protease , Calcium Channel , COX , HIV Protease |
Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced b... | |||
T23816 | BPIC | ||
BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals. | |||
T36500 | Cyanidin 3-O-arabinoside | ||
Cyanidin 3-O-arabinoside is an anthocyanin antioxidant that has been found in eggplant. It scavenges radicals in a Trolox equivalent antioxidant capacity (TEAC) assay. | |||
T39434 | HKOH-1 | ||
HKOH-1 is a highly sensitive and selective fluorescent probe for detecting endogenous hydroxyl radicals. | |||
T39600 | HKOH-1r | ||
HKOH-1r is a highly sensitive and selective fluorescent probe which is used for detecting endogenous hydroxyl radicals in living cells. | |||
T40936 | Quinclorac | ||
Quinclorac, a commonly used agricultural herbicide, elicits oxidative stress by triggering the production of free radicals and altering the antioxidant defense system. | |||
T35590 | Graphislactone A | ||
Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. olivacea. It exhibits dose-dependent scavenging activity against DPPH radicals and metal ion-dependent hydroxyl radicals in vitro. Graphislact... | |||
T75354 | RH-EDA | ||
RH-EDA, a rhodamine-based turn-on fluorescent probe, detects hydroxyl radicals ([OH]) in living systems. | |||
T21338 | Methylprednisolone Acetate | Depo-Medrate,Depometicort,Depo-Medrin,Depo-medrol,Depomedrone,Lemod | Reactive Oxygen Species |
Methylprednisolone Acetate(Depo-Medrate) has the ability to inhibit oxygen free radicals and can be used to treat acute spinal cord injuries. | |||
T36501 | CYPMPO | RR 071 | |
CYPMPO is a free radical spin trap with excellent trapping capabilities toward hydroxyl and superoxide radicals in biological and chemical systems. Decay of the superoxide adduct of CYPMPO proceeds in an apparent first o... | |||
T38099 | APF | ||
APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase... | |||
T40625 | Plumbic acetate | ||
Plumbic acetate can provide either acetate radicals or acetoxonium ions. Plumbic acetate may be an acceptable oxidising agent for the preparation of sulphur (VI) systems, as witnessed by its reaction with thiodithiazyl d... | |||
T76576 | Arg-Tyr | ||
Arg-Tyr, a dipeptide, demonstrates significant activity in scavenging hydroxyl radicals and hydrogen peroxide [1]. | |||
T61312 | Antioxidant agent-3 | ||
Antioxidant agent-3 (Compound 14q), a potent antioxidant, exhibits strong scavenging activity against DPPH radicals and ABTS+ radicals, with IC50 values of 26.58 μM and 30.31 μM, respectively. Additionally, it enhances t... | |||
T36175 | AAPH | ||
AAPH is a water-soluble azo compound which is used extensively as a free radical generator, often in the study of lipid peroxidation and the characterization of antioxidants.[1],[2],[3],[4] Decomposition of AAPH produces... | |||
T68675 | Porfiromycin | ||
Porfiromycin is a n N-methyl derivative of the antineoplastic antibiotic mitomycin C isolated from the bacterium Streptomyces ardus and other Streptomyces bacterial species. Bioreduced porfiromycin generates oxygen radic... | |||
T60434 | Pentifylline | ||
Pentifylline is a vasodilator that inhibits platelet aggregation and thromboxane A2 synthesis, decrease the release of free radicals, and may be neuroprotective [1]. | |||
T41058 | Nelonemdaz potassium | Neu2000potassium,Salfaprodil | |
Nelonemdaz potassium (also known as Salfaprodil) is a potent NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). This compound exhibits remarkable neuroprotection against cell death induced by bot... | |||
T36174 | Methyl 3,4-Dihydroxyphenylacetate | ||
Methyl 3,4-dihydroxyphenylacetate is a polyphenol that has been found inI. aquifoliumseeds and has antioxidant and antiviral activities.1,2It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50= 0... | |||
T36027 | DEPMPO-biotin | ||
DEPMPO is a nitrone that is used to spin trap reactive O-, N-, S-, and C-centered radicals and allow their characterization when used in association with electron spin resonance. It is noted for the stability of adducts ... | |||
T38370 | CAY10731 | ||
CAY10731 is a fluorescent probe for hydrogen sulfide (H2S).[1] Upon reaction with H2S, fluorescein (FITC) is released and its fluorescence can be used to detect H2S. FITC displays excitation/emission maxima of 485/535 nm... | |||
T75332 | 7-Hydroxy-4-methyl-2(1H)-quinolone | ||
7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b), a fluorescent hydroxylated derivative, serves as a probe for detecting hydroxyl radicals associated with DNA damage [1]. For preservation, it should be protected from lig... | |||
T78360 | Glyceraldehyde phosphate dehydrogenase | GAPDH,G3PDH,GADPH | |
Glyceraldehyde phosphate dehydrogenase, targeted by anti-thymocyte and anti-apoptotic agents, catalyzes the oxidation of reduced nicotinamide adenine dinucleotide (NADH) by perhydroxyl radicals [1] [2]. | |||
T35708 | N-acetyl-5-Aminosalicylic Acid | ||
N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid and its prodrug form, sulfasalazine . It is formed in the liver, intestinal lumen, and colonic epithelial cells via N-ac... | |||
T80909 | Tyrosinase-IN-19 | Tyrosinase | |
Tyrosinase-IN-19 (compound 9), a competitive tyrosinase inhibitor, exhibits potent antioxidant activities by neutralizing ROS, ABTS+, and DPPH radicals and demonstrates dose-dependent suppression of tyrosinase expression... | |||
T71326 | 1,3,7-Trimethyluric Acid-d9 | ||
1,3,7-Trimethyluric acid-d9 is intended for use as an internal standard for the quantification of 1,3,7-trimethyluric acid by GC- or LC-MS. 1,3,7-Trimethyluric acid is a derivative of uric acid and a metabolite of caffei... | |||
T83816 | Cytidine-5'-O-(2-thiodiphosphate) sodium | CDP-β-S | |
Cytidine-5’-O-(2-thiodiphosphate) (CDP-β-S), a non-hydrolyzable derivative of CDP exhibiting antioxidant activity, effectively scavenges free radicals as evidenced by its performance in the Trolox equivalent absorbance c... | |||
T34112 | Porfimer Sodium | DHE,dihematoporphyrin ether,CL184116,CL-184116,CL 184116,Porfimer | |
Porfimer sodium is t he sodium salt of a mixture of oligomers formed by ether and ester linkages of up to eight porphyrin units with photodynamic activity. Absorbed selectively by tumor cells, porfimer produces oxygen ra... | |||
T38071 | HPF | ||
The biology of highly reactive oxygen radical species is of great interest in many biomedical research disciplines, including neurodegeneration, aging, cancer, and infectious diseases.[1] There are a number of fluorescen... | |||
T72121 | Tetrahydroxyquinone monohydrate | Tetrahydroxybenzoquinone monohydrate,Tetrahydroxy-1,4-benzoquinone monohydrate,Tetrahydroxy-1,4-benzoquinone monohydrate ; Tetrahydroxybenzoquinone monohydrate | |
Tetrahydroxyquinone monohydrate (Tetrahydroxy-1,4-benzoquinone monohydrate), serving as an early-stage anticataract agent, is a redox-active benzoquinone. This compound engages in redox cycling with semiquinone radicals,... | |||
T81864 | MAQAAEYYR | ||
MAQAAEYYR, an antioxidant peptide derived from the pancreatin hydrolysate of C-phycocyanin, exhibits potent scavenging activities against DPPH and ABTS radicals. It also confers protection to zebrafish larvae against oxi... | |||
T69014 | Sekikaic Acid | ||
Sekikaic acid is a phenolic lichen metabolite that has been found in H. obscurata and has diverse biological activities. It scavenges superoxide and DPPH radicals in cell-free assays when used at a concentration of 0.5 µ... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TQ0211 | Brusatol | (+)-Brusatol,NSC 172924 | Others , Ferroptosis , Nrf2 |
Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2. | |||
T8177 | Galactinol | Others | |
Galactinol Hydrate scavenges hydroxyl free radicals and protects plant cells from oxidative damage. | |||
TJS0315 | 4-Methyldaphnetin | 7,8-Dihydroxy-4-methylcoumarin,DHMC | Apoptosis , Lipoxygenase |
4-Methyldaphnetin (DHMC) is a potent inhibitor (low micromolar) of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals, but may be pro-oxidant (enhancing generation of hydr... | |||
T4931 | Dihydroxyfumaric acid hydrate | Others , Endogenous Metabolite | |
Dihydroxyfumaric acid is a known generator of superoxide anions and by hydroxyl free radicals. Dihydroxyfumarate exposure can cause insulin inhibitory effects. It can spontaneously convert to hydroxypyruvate or to oxalog... | |||
T6S1930 | Schisanhenol | Schizanhenol,Gomisin-K3 | Antioxidant |
1. Schisanhenol (Schizanhenol) can protect against adriamycin induced heart mitochondrial toxicity. 2. Schisanhenol has antioxidative effect on human LDL oxidation, may be through scavenging free radicals. 3. Schisanheno... | |||
T3S0289 | Araloside X | Calcium Channel | |
Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane perox... | |||
T5S0285 | Cistanoside A | Others | |
1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respirat... | |||
T19792 | 1,3,7-Trimethyluric acid | Others | |
1,3,7-Trimethyluric acid is a purine alkaloid that occurs as a minor metabolite of caffeine in humans. As an antioxidant, it has shown an ability to scavenge hydroxyl radicals as well as protective potential against lipi... | |||
T1085 | L-Glutathione reduced | GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,Tathion | Ferroptosis , Reactive Oxygen Species , Endogenous Metabolite , Glutathione reductase |
L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutathione reduced is a cofactor for certain enzymes and is invo... | |||
T5S0089 | Kaempferol-3-O-glucorhamnoside | Kaempferol 3-glucorhamnoside | Antioxidant , p38 MAPK , NF-κB |
Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside), a flavonoid derived from plant Thesium chinense Turcz, inhibits inflammatory responses via MAPK and NF-κB pathways in vitro and in vivo[1]. Kaempferol-3-O-gl... | |||
TN1601 | Effusol | Caspase | |
Effusol is a natural product, exhibits potent scavenging activity for DPPH and ABTS radicals(IC50 values of 79 μM and 2.73 μM, respectively). Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampa... | |||
T0562 | Protocatechuic acid | 3, 4-Dihydroxybenzoic acid,Protocatechuate,3,4-Dihydroxybenzoic acid | Others |
Protocatechuic acid (3, 4-Dihydroxybenzoic acid) (3, 4-dihydroxybenzoic acid) is a natural phenolic compound found in many edible and medicinal plants. Recent studies indicate that it could be used as a protective agent ... | |||
T5S2254 | Swertianolin | Bellidifolin-8-O-Glucoside | Others , HBV , Antibacterial , AChE |
1. Swertianolin (Bellidifolin-8-O-Glucoside), mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentianaceae species. 2. Swertianolin... | |||
T4704 | L-Anserine nitrate | L-Anserine nitrate salt | Others , Endogenous Metabolite |
L-Anserine nitrate (L-Anserine nitrate salt) is a dipeptide found in most animal tissues. In model systems it is a potent Antioxidant and scavener of hydroxyl radicals. The compound inhibits nonenzymatic protein glycatio... | |||
T3388 | Calycosin-7-O-β-D-glucoside | calycosin-7-O-beta-D-glucopyranoside,Calycosin-7-O-beta-D-glucoside | MMP , Reactive Oxygen Species |
Calycosin-7-O-β-D-glucoside (calycosin-7-O-beta-D-glucopyranoside) possesses a protective effect on rat hepatocytes, an inhibitory effect on COX-2 activity. Calycosin 7-O-β-D-glucoside has antimicrobial activity. Calycos... | |||
T7984 | 2-Hydroxyflavanone | Others | |
2-Hydroxyflavanone is a naturally occurring flavonoid found in many plants and fruits. It has antioxidant, anti-inflammatory and anti-tumor activity, scavenging free radicals, reducing inflammation and inhibiting the gro... | |||
T3606 | γ-Oryzanol | Gamma-Oryzanol,Oliver,Gammariza | DNA Methyltransferase |
γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the destruction of free radicals in the skin. It has recently b... | |||
T41242 | Uric acid sodium | Reactive Oxygen Species | |
Uric acid sodium, scavengers of oxygen radicals, is a potent and common antioxidant that helps maintain stable blood pressure and resist oxidative stress. Uric acid sodium, which removes reactive oxygen species (ROS) suc... | |||
TN1962 | Myricetin 3-O-galactoside | Myricetin 3-O-beta-D-galactopyranoside | NOS , Xanthine Oxidase |
Myricetin 3-O-galactoside (Myricetin 3-O-beta-D-galactopyranoside) can inhibit xanthine oxidase (xanthine oxidase; XO) activity, lipid peroxidation and scavenging free radicals. Myricetin 3-O-galactoside has many effects... | |||
TN1831 | Macranthoside A | Kalopanaxsaponin H | Antioxidant |
Macranthoside A (Kalopanaxsaponin H) is a triterpenoid glycoside extracted from rehmannia and belongs to the iridoterpenoid synthesis. Macranthoside A has anti-inflammatory, antioxidant, antibacterial and neuroprotective... | |||
TN3972 | Epimedokoreanin B | Apoptosis , Others , Antibacterial | |
Epimedokoreanin B (EKB), an isoprenylated flavonoid isolated from Korean Epimedium, exhibited anticancer activity in human non-small cell lung cancer (NSCLC) A549 and NCI-H292 cells.Epimedokoreanin B also possesses anti-... | |||
T35749 | Thymohydroquinone | Thymoquinol | Antioxidant , Reactive Oxygen Species |
Thymohydroquinone (Thymoquinol) is a monoterpenoid phenolic compound found in thyme, oregano, and other plants in the labiaceae family. Thymohydroquinone inhibits cancer cell growth, reduces oxidative stress and modulate... | |||
TN2015 | Ophiopogonanone E | Others | |
Ophiopogonanone E has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro. | |||
TN3677 | Cleroindicin B | Others | |
Cleroindicin B shows weak scavenging action on 2,2-diphenyl-l-picrylhydrazyl and hydroxyl radicals. | |||
TN2013 | Ophiopogonanone A | Others | |
Ophiopogonanone A has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro. | |||
TN4404 | Ladanein | HCV Protease | |
Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radicals DPPH and ABTS +.scavenging activity, it also displays m... | |||
TN5471 | 5,7-Dihydroxy-3-(4-hydroxy-3,5-dimethoxybenzyl)-6,8-dimethylchroman-4-one | ||
5,7-Dihydroxy-3-(4-hydroxy-3,5-dimethoxybenzyl)-6,8-dimethylchroman-4-one has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro.It shows a strong c... | |||
TN1431 | Baohuoside VII | Others | |
Baohuoside aglycone possesses cardioprotective effect in prevention of ischemia/ reperfusion injury and reduce the myocardial infraction, the mechnism is due to the reduction of the injury of free radicals. Baohuoside VI... | |||
T36513 | Pyranonigrin A | ||
Pyranonigrin A is a fungal metabolite originally isolated from Aspergillus that has antioxidant activity. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH;) free radicals in a cell-free assay (IC50 = 132.9 μM). Pyranonig... | |||
T75699 | Coenzyme Q6 | ||
Coenzyme Q6 (Ubiquinone 30), an isoprenylated benzoquinone lipid, plays a pivotal role in respiratory electron transport and acts as a lipid antioxidant. Besides, it possesses antioxidant properties that inhibit the gene... | |||
TN3380 | Alloisoimperatorin | AChR | |
Alloisoimperatorin is a candidate of AChE inhibitors, it displays potent antioxidant effects against the DPPH radical and against renal epithelial cell injury by using AAPH to generate peroxyl radicals in vitro. Alloisoi... | |||
TMA0291 | Dehydroglyasperin D | GSK-3 , p38 MAPK , ROS , Akt , COX , PI3K , DNA/RNA Synthesis , Prostaglandin Receptor , JNK | |
Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 human colorectal cancer cells through direct interaction wit... | |||
TN4605 | Myriceric acid B | HIV Protease | |
Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41 and can serve as a lead compound for developing novel anti-HIV-1 drug. Myriceric acid B scavenges DPPH free radicals with IC50 value of 21.8 uM, it inhibi... | |||
T83026 | Antioxidant agent-18 | ||
Antioxidant Agent-18 (Compound 5), a flavonol glycoside derived from Ginkgo biloba, exhibits antioxidant properties through its ability to scavenge DPPH radicals (IC50: 15.8 μM) and reduce cytochrome c (IC50: 14.7 μM). | |||
TN4263 | Isoangustone A | MMP , GSK-3 , NF-κB , ROS , Akt , PI3K , CDK , JNK | |
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation by targeting PI3K, MKK4, and MKK7 in human melanoma. Isoang... | |||
TN2243 | Sugiol | 10-Deoxoxanthoperol | IL Receptor , TNF , ROS |
Sugiol (10-Deoxoxanthoperol) has antioxidant efficacy, it has significant scavenging activities of 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide and hydroxyl free radicals. Sugiol's efficacy in inhibiting the ... | |||
T35758 | Butyrolactone V | ||
Butyrolactone V is a fungal metabolite that has been found in A. terreus and has antiprotozoal, antioxidant, and anticancer activities.1,2,3 It is active against the P. falciparum strain K1 (IC50 = 7.9 μg/ml) and L. amaz... | |||
T36179 | Aspulvinone O | ||
Aspulvinone O is a fungal metabolite that has been found in P. variotti and has antioxidant and anticancer activities.1,2 It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 11.6 μM).1 Aspulv... | |||
T83876 | L-Ascorbic Acid 6-stearate | L-Ascorbyl-6-stearate,6-O-Stearoyl-L-Ascorbic Acid | |
L-Ascorbic acid 6-stearate, a compound derived from L-ascorbic acid and stearic acid identified in K. coccinea, exhibits antioxidant and anticancer properties. It effectively scavenges DPPH radicals in cell-free assays (... | |||
T36000 | 3-Hydroxyterphenyllin | ||
3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPH-01317 | SOD3 Protein, Human, Recombinant (His) | Human | E. coli |
Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. SOD3 Protein, Human, Recombinant (His) is expressed in E. coli expre... | |||
TMPH-03378 | SOD1 Protein, Rat, Recombinant (His) | Rat | P. pastoris (Yeast) |
Destroys radicals which are normally produced within the cells and which are toxic to biological systems. SOD1 Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 17.... | |||
TMPH-02918 | SOD1 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
Destroys radicals which are normally produced within the cells and which are toxic to biological systems. SOD1 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 1... | |||
TMPY-01585 | SOD1 Protein, Human, Recombinant (His) | Human | E. coli |
SOD1 belongs to the Cu-Zn superoxide dismutase family. It binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmi... | |||
TMPH-01318 | SOD3 Protein, Human, Recombinant | Human | E. coli |
Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. SOD3 Protein, Human, Recombinant is expressed in E. coli expression ... | |||
TMPH-02917 | SOD1 Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
Destroys radicals which are normally produced within the cells and which are toxic to biological systems. SOD1 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The pr... | |||
TMPH-00052 | Superoxide dismutase [Fe] Protein, Anabaena sp., Recombinant (His & KSI) | Anabaena | E. coli |
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Superoxide dismutase [Fe] Protein, Anabaena sp., Recombinant (His & KSI) is expressed in E. coli ... | |||
TMPH-03612 | SodC Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) | Mycobacterium tuberculosis | E. coli |
Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes. SodC Protein, Mycobacterium tuberculosis, Recomb... | |||
TMPJ-01248 | Cytoglobin/CYGB Protein, Human, Recombinant (His) | Human | E. coli |
Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be... | |||
TMPJ-00946 | TALDO1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Transaldolase (TALDO1) belongs to the transaldolase family of Type 1 subfamily. TALDO1 is expressed selectively in oligodendrocytes of the brain. TALDO1 is a key enzyme of the nonoxidative pentose phosphate pathway provi... | |||
TMPH-00035 | Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His) | Agaricus bisporus | Baculovirus Insect Cells |
Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-quinones, which evolve spontaneously to produce intermediates, wh... | |||
TMPJ-00104 | SOD2 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Superoxide Dismutase (SOD2) is a number of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. The SOD2 protein transforms to... | |||
TMPJ-00979 | GSH-S Protein, Human, Recombinant (His) | Human | E. coli |
Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glyci... | |||
TMPJ-00887 | NFKB1 Protein, Human, Recombinant (His) | Human | E. coli |
The 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radica... | |||
TMPY-02209 | CUTC Protein, Human, Recombinant (His) | Human | E. coli |
Copper homeostasis protein cutC homolog, also known as CGI-32 and CUTC, is a cytoplasm and nucleus protein which belongs to theCutC family. CUTC may play a role in copper homeostasis. It can bind one Cu1+per subunit. ... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L2910 | Antioxidant Compound Library | 1314 compounds | |
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. ... | |||
L6120 | Flavonoid Natural Product Library | 514 compounds | |
A unique collection of 514 flavonoids can be used for high throughput and high content screening; |