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天然化合物

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カタログ番号	製品名	別名	ターゲット
T67944	P38 MAP Kinase Inhibitor Ⅵ		p38 MAPK
	p38 MAP Kinase Inhibitor Ⅵ is a potent p38 MAP Kinase inhibitor with anti-inflammatory activity.		p38 MAPK
TP2269	MAP kinase fragment [Multiple species]		Others
	This Mitogen-activated protein kinase (MAP kinase) fragment has a peptide sequence of Lys-Tyr-Ile-His-Ser-Ala-Asn-Val-Leu. The MAP kinases are serine/threonine-specific protein kinases belonging to the CMGC (CDK/MAPK/GSK...		Others
T36011	P38 MAP Kinase Inhibitor IV	p38 MAPK Inhibitor IV
	p38 MAPK inhibitor IV is an ATP-competitive inhibitor of p38 MAP kinases with IC50 values of 0.13, 0.55, 5.47, and 8.63 μM for p38α, p38β, p38x, and p38δ, respectively, in vitro.[1] It also inhibits LPS-induced TNF-α an...
T9504	MAP4343		Microtubule Associated
	Map4343 is a 3-methyl ether derivative of pregnenolone. Map4343 binds to microtubule associated protein 2 (MAP2) in vitro and stimulates tubulin polymerization, resulting in enhanced neurite extension and protection of n...		Microtubule Associated
T60011	HS220		MAPK
	HS220 is an inhibitor of TAK1 which plays a key role in the signaling pathways of inflammation and cell survival.		MAPK
T11942	MAP4K4-IN-3	Compound 17	MAPK
	MAP4K4-IN-3 (Compound 17) may be a viable target for antidiabetic agents, a serine/threonine protein kinase.		MAPK
T3350	Selonsertib	GS-4997	Apoptosis , ASK , MAPK
	Selonsertib (GS-4997) is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.		Apoptosis , ASK , MAPK
T15250	ETC-206		MNK
	ETC-206 is a selective inhibitor of MNK1 and MNK2 (IC50s: 64 nM and 86 nM).		MNK
T22961	MAP4		Others
	metabotropic glutamate receptor modulator		Others
T3101	NQDI-1	NQDI1,NQDI 1	Apoptosis , ASK , MAPK
	NQDI-1 (NQDI 1) is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50/Ki: 3 μM/500 nM).		Apoptosis , ASK , MAPK
T5190	GS-444217	GS 444217,GS444217	Apoptosis , ASK , MAPK
	GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM).		Apoptosis , ASK , MAPK
T5643	NG25		MAPK
	NG25 is a potent dual TAK1 and MAP4K2 inhibitor, with IC50s of 149 nM and 21.7 nM, respectively.		MAPK
T13099	TC ASK 10		ASK , MAPK
			ASK , MAPK
T16987	TAO Kinase inhibitor 1		Others , MAPK
	TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death. TAO Kinase inhibitor 1 is a selective and ATP-competitive thousand-and-one amino acid kinases inhibitor (IC50s: 11 to 15 nM for TAOK1 and 2, respectiv...		Others , MAPK
T9377	ASK1-IN-2		Apoptosis , ASK , MAPK
	ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can potentially be used as a therapeutic strategy for ulcerative colitis[1].		Apoptosis , ASK , MAPK
T3707	GNE-3511	GNE3511	DNA Alkylation , MAPK
	GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors.		DNA Alkylation , MAPK
T4264	Takinib	EDHS-206	Apoptosis , MAPK
	Takinib (EDHS-206) is a specific and effective TAK1 inhibitor(IC50= 9.5 nM).		Apoptosis , MAPK
T3468	Tomivosertib	eFT508	MNK , PD-1/PD-L1
	Tomivosertib (eFT508) is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 nM.		MNK , PD-1/PD-L1
T14988	CMPD1		MAPK
	CMPD1 is a non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor(apparent Ki (Kiapp): 330 nM).		MAPK
T4424	SLV-2436	SEL-201,SLV 2436,SEL201-88	MNK
	SLV-2436 (SEL201-88) is a novel effective and ATP-competitive inhibitor of MNK1 and MNK2 (IC50: 10.8/5.4 nM).		MNK
T12058	MK2-IN-3 hydrate	MK-2 Inhibitor III	ERK , MAPK , MNK
	MK2-IN-3 hydrate (MK-2 Inhibitor III) is an orally active, selective, and ATP-competitive inhibitor of MAPKAP-K2 (MK-2) (IC50 of 0.85 nM)		ERK , MAPK , MNK
T6440	CGP 57380	MNK1 Inhibitor	Apoptosis , MNK
	CGP 57380 (MNK1 Inhibitor) is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases.		Apoptosis , MNK
T4442	MK2-IN-1 hydrochloride	MK2 Inhibitor,MK 25	MAPK
	MK2-IN-1 hydrochloride (MK 25) is a highly selective, non-ATP competitive inhibitor of p38/mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2 or MK2, IC50: 0.11 μM) [1].		MAPK
T16501	PF-3644022		p38 MAPK , Serine Protease , MAPK
	PF-3644022 is an effective, selective, and ATP-competitive MAPKAPK2 (MK2) inhibitor (IC50: 5.2 nM and a Ki of 3 nM). PF-3644022 potently inhibits TNFα production and has an anti-inflammatory effect. PF-3644022 also inhib...		p38 MAPK , Serine Protease , MAPK
T9034	MK2-IN-3	MK2 Inhibitor III	MAPK
	MK2-IN-3 (MK2 Inhibitor III) is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis		MAPK
T1667	Tandutinib	MLN518,CT53518,NSC726292	Apoptosis , FLT , CSF-1R , PDGFR , Src , c-Kit
	Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versu...		Apoptosis , FLT , CSF-1R , PDGFR , Src , c-Kit
T7196	HG-10-102-01		LRRK2
	HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).		LRRK2
T36010	P38 MAPK Inhibitor		p38 MAPK
	p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS.		p38 MAPK
T7367	Acumapimod	BCT-197	p38 MAPK , Autophagy
	Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).		p38 MAPK , Autophagy
T16682	Pumaprazole	BY-841	Proton pump
	Pumaprazole (BY-841) is an antagonist of a reversible proton pump.		Proton pump
T12850	Dilmapimod	SB-681323,GW 681323	p38 MAPK , Autophagy
	Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.		p38 MAPK , Autophagy
T6089	Neflamapimod	VX-745	p38 MAPK , Autophagy
	Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.		p38 MAPK , Autophagy
T1764	Adezmapimod	PB 203580,RWJ 64809,SB203580	Mitophagy , p38 MAPK , Autophagy
	Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive. Adezmapimod possesses autophagy and mitochondrial autophagy activating activity. Adezmapimod displays more than 100...		Mitophagy , p38 MAPK , Autophagy
T63067	Emprumapimod
	Emprumapimod is a selective, orally active inhibitor of p38α MAPK. emprumapimod acts on RPMI-8226 cells and directly inhibits LPS-induced IL-6 production with an IC50 value of 100 pM. emprumapimod can be used to study di...
T22724	Dimaprit dihydrochloride		NOS , NO Synthase , Histamine Receptor
	Dimaprit dihydrochloride is a selective histamine H2 receptor agonist. Dimaprit dihydrochloride also inhibits nNOS with an IC50 of 49 μM. It can stimulate gastric acid secretion.		NOS , NO Synthase , Histamine Receptor
T76742	Emapalumab	NI-0501	COX
	Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab ha...		COX
T63119	NF-κB/MAPK-IN-1		NF-κB , MAPK
	NF-κB/MAPK-IN-1 is a potent dual inhibitor of the NF-κB and MAPK pathways with potential anti-inflammatory activity, inhibition of NO production, and inhibition of LPS-induced activation of iNOS, COX-2, ERΚ and P38. NF-κ...		NF-κB , MAPK
T2675	Bentamapimod	AS 602801	JNK
	Bentamapimod (AS 602801) is a novel, orally active inhibitor of JNK.		JNK
T12871	Talmapimod	SCIO-469	p38 MAPK
	Talmapimod (SCIO-469) is an selective, orally active, and ATP-competitive p38α inhibitor with IC50 of 9 nM and 90 nM for p38α and p38β, respectively. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 ...		p38 MAPK
T6277	Doramapimod	BIRB 796	Raf , p38 MAPK , Autophagy
	Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.		Raf , p38 MAPK , Autophagy
T2277	Losmapimod	GSK-AHAB,GW856553X,GW856553,SB856553	p38 MAPK , Autophagy
	Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).		p38 MAPK , Autophagy
T2371	Emapunil	AC-5216,XBD-173	Others
	Emapunil (XBD-173) is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO.		Others
T77751	Imaprelimab	PRX-003	Others
	Imaprelimab (PRX-003) is a humanized IgG1 κmonoclonal antibody against melanoma cell adhesion molecule (MCAM). Imaprelimab has antitumor activity and can be used to study inflammation, tumors, and psoriasis.		Others
T77780	Zamaporvint	RXC004	Others
	Zamaporvint (RXC004) is a selective, orally active and potent inhibitor of the Wnt pathway that acts on the membrane-bound fatty acyltransferase porcupine to block Wnt ligand palmitoylation, secretion, and pathway activa...		Others
T12347	P38-α MAPK-IN-1		p38 MAPK , Autophagy
	p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor(IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay).		p38 MAPK , Autophagy
T38570	DMAPP triammonium	Dimethylallyl diphosphate triammonium,Dimethylallyl Pyrophosphate triammonium salt	Others
	DMAPP triammonium (Dimethylallyl diphosphate triammonium) is one of the prerequisite substances for an isoprenoid involved in the mevalonate (MVA) pathway, which can be used in the study of metabolism-related diseases.		Others
T11943	MAPK13-IN-1		p38 MAPK
	MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).		p38 MAPK
T6927	Pamapimod	R1503,Ro4402257	p38 MAPK , Autophagy
	Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectiv...		p38 MAPK , Autophagy
T38796L	MBP MAPK Substrate acetate	MBP MAPK Substrate acetate(138028-00-9 free base)	MAPK
	MBP MAPK Substrate acetate can be used as an exogenous substrate for MAPK.		MAPK
T0172	Maprotiline hydrochloride	Maprotiline HCl,Psymion,Deprilept,Ludiomil	5-HT Receptor , Adrenergic Receptor , AChR , Norepinephrine , Autophagy , Histamine Receptor
	Maprotiline hydrochloride (Psymion) is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.

Compounds

p38 MAP Kinase Inhibitor Ⅵ

T67944

Synonym:

Target: p38 MAPK

MAP kinase fragment [Multiple species]

TP2269

Synonym:

Target: Others

p38 MAP Kinase Inhibitor IV

T36011

Synonym: p38 MAPK Inhibitor IV

Target: Microtubule Associated

Target: Apoptosis, ASK, MAPK

MAP4

Synonym: NQDI1,NQDI 1

Target: Apoptosis, ASK, MAPK

GS-444217

T5190

Synonym: GS 444217,GS444217

Target: Apoptosis, ASK, MAPK

TAO Kinase inhibitor 1

T16987

Synonym:

Target: Others, MAPK

ASK1-IN-2

T9377

Synonym:

Target: Apoptosis, ASK, MAPK

GNE-3511

T3707

Synonym: GNE3511

Target: DNA Alkylation, MAPK

Takinib

T4264

Synonym: EDHS-206

Target: Apoptosis, MAPK

Tomivosertib

T3468

Synonym: eFT508

Target: MNK, PD-1/PD-L1

Synonym: SEL-201,SLV 2436,SEL201-88

Target: MNK

MK2-IN-3 hydrate

T12058

Synonym: MK-2 Inhibitor III

Target: ERK, MAPK, MNK

CGP 57380

T6440

Synonym: MNK1 Inhibitor

Target: Apoptosis, MNK

MK2-IN-1 hydrochloride

T4442

Synonym: MK2 Inhibitor,MK 25

Target: p38 MAPK, Serine Protease, MAPK

MK2-IN-3

T9034

Synonym: MK2 Inhibitor III

Target: MAPK

Tandutinib

T1667

Synonym: MLN518,CT53518,NSC726292

Target: Apoptosis, FLT, CSF-1R, PDGFR, Src, c-Kit

Target: p38 MAPK, Autophagy

Synonym: SB-681323,GW 681323

Target: p38 MAPK, Autophagy

Neflamapimod

T6089

Synonym: VX-745

Target: p38 MAPK, Autophagy

Adezmapimod

T1764

Synonym: PB 203580,RWJ 64809,SB203580

Target: Mitophagy, p38 MAPK, Autophagy

Dimaprit dihydrochloride

T22724

Synonym:

Target: NOS, NO Synthase, Histamine Receptor

Target: NF-κB, MAPK

Target: Raf, p38 MAPK, Autophagy

Losmapimod

T2277

Synonym: GSK-AHAB,GW856553X,GW856553,SB856553

Target: p38 MAPK, Autophagy

Emapunil

T2371

Synonym: AC-5216,XBD-173

Target: p38 MAPK, Autophagy

DMAPP triammonium

T38570

Synonym: Dimethylallyl diphosphate triammonium,Dimethylallyl Pyrophosphate triammonium salt

Synonym: R1503,Ro4402257

Target: p38 MAPK, Autophagy

MBP MAPK Substrate acetate

T38796L

Synonym: MBP MAPK Substrate acetate(138028-00-9 free base)

Target: MAPK

Maprotiline hydrochloride

T0172

Synonym: Maprotiline HCl,Psymion,Deprilept,Ludiomil

Target: 5-HT Receptor, Adrenergic Receptor, AChR, Norepinephrine, Autophagy, Histamine Receptor

カタログ番号	製品名	別名	ターゲット
T14055	5Z-7-Oxozeaenol	FR148083,L783279,LL-Z 1640-2	VEGFR , FLT , MEK , MAPK , PDGFR , Antibiotic , Src
	5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is ...		VEGFR , FLT , MEK , MAPK , PDGFR , Antibiotic , Src
T11060	DMAPT	Dimethylamino Parthenolide	NF-κB
	DMAPT (Dimethylamino Parthenolide) is a water-soluble analogue of Parthenolide (PTL). It is an orally active NF-κB inhibitor with an LD50 of 1.7 μM on primary acute myeloid leukemia cells.		NF-κB
T36303	Psammaplin A
	Psammaplin A, a marine metabolite, functions as a robust inhibitor of HDAC and DNA methyltransferases, displaying notable potency and selectivity as a DAC1 inhibitor, with an IC50 value of 0.9 nM. It exhibits antimicrobi...
TN5795	Chimaphilin	2,7-Dimethyl-1,4-naphthoquinone
	Chimaphilin is a natural product for research related to life sciences. The catalog number is TN5795 and the CAS number is 482-70-2.
TN1505	Clemaphenol A		Others
	Clemaphenol A is a natural product from Cynanchum auriculatum.		Others
T3S0462	Rehmapicroside		Others
	Rehmapicroside is a natural product of Rehmannia, Scrophulariaceae. The catalog number is T3S0462 and the CAS number is 104056-82-8. Rehmapicroside can be used as a reference standard.		Others
TN2336	Rehmapicrogenin		Nrf2
	Rehmapicrogenin regulates the Nrf2/ARE signaling pathway. Nrf2/ARE signaling pathway is the most important pathway of oxidative stress.		Nrf2
TN5796	3-Hydroxychimaphilin
	3-Hydroxychimaphilin is a natural product for research related to life sciences. The catalog number is TN5796 and the CAS number is 33253-99-5.
T40454	DMAPP	Dimethylallyl diphosphate
	DMAPP, also known as Dimethylallyl pyrophosphate, is an isoprenoid precursor found in all life forms. It serves as an isomer of isopentenyl pyrophosphate (IPP).
T80259	PMAP-23
	PMAP-23 is an antimicrobial peptide (AMP) with biological activity, derived from porcine myeloid cells.
T7030	Anemarsaponin B		p38 MAPK , NF-κB , MEK , COX , NO Synthase
	Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B c...		p38 MAPK , NF-κB , MEK , COX , NO Synthase
T6S1740	Nardosinone		Others
	1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed t...		Others
T2787	Picroside I	6'-Cinnamoylcatalpol	MMP , STAT
	Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may be the valuable anti-invasive drug ...		MMP , STAT
TN2354	Methylnissolin	3-Hydroxy-9,10-dimethoxyptercarpan	ERK , PDGFR
	Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.		ERK , PDGFR
TN1338	7Beta-Hydroxycholesterol		LDL , Calcium Channel , MAPK
	7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells.		LDL , Calcium Channel , MAPK
TN2039	Panaxydol		cAMP , p38 MAPK , JNK
	Panaxydol has anti-cancer activity, can inhibit the growth and apoptosis of cancer cells, the signaling mechanisms involve a [Ca(2+)](i) increase, JNK and p38 MAPK activation, cAMP, MAP kinase and ROS generation through ...		cAMP , p38 MAPK , JNK
T10910	Cycloartenol		Others
	Cyclopentanol is a plant sterol compound and one of the key precursors for biosynthesis of various sterol compounds. Cycloartenol inhibits the migration of glioma cells and inhibits the phosphorylation of p38 MAP kinase....		Others
TN5153	Torilin		MMP , ERK , IκB/IKK , p38 MAPK , NF-κB , Tyrosinase , Reductase , DNA/RNA Synthesis , JNK
	Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linolenic acid (IC50 = 160.3 +/- 24.62 microM) but is weaker than fi...

天然物製品

5Z-7-Oxozeaenol

T14055

Synonym: FR148083,L783279,LL-Z 1640-2

Target: VEGFR, FLT, MEK, MAPK, PDGFR, Antibiotic, Src

DMAPT

T11060

Synonym: Dimethylamino Parthenolide

Synonym: 2,7-Dimethyl-1,4-naphthoquinone

Synonym: Dimethylallyl diphosphate

Target: p38 MAPK, NF-κB, MEK, COX, NO Synthase

Synonym: 6'-Cinnamoylcatalpol

Target: MMP, STAT

Methylnissolin

TN2354

Synonym: 3-Hydroxy-9,10-dimethoxyptercarpan

Target: ERK, PDGFR

7Beta-Hydroxycholesterol

TN1338

Synonym:

Target: LDL, Calcium Channel, MAPK

Panaxydol

TN2039

Synonym:

Target: cAMP, p38 MAPK, JNK

Target: MMP, ERK, IκB/IKK, p38 MAPK, NF-κB, Tyrosinase, Reductase, DNA/RNA Synthesis, JNK

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00247	METAP1 Protein, Human, Recombinant	Human	E. coli
	Methionine Aminopeptidase 1 is a member of the M24 family of metalloproteases. METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and develop...
TMPY-01344	MAP1D Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Methionine aminopeptidase 1D, also known as MAP1D, is a member of the peptidase M24A family. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localizatio...
TMPK-00705	MASP2 Protein, Human, Recombinant (His)	Human	E. coli
	The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As...
TMPK-00581	MASP2 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	MASP2 Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.7 kDa and the accession number is A2VCV7.
TMPK-00582	MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated	Rat	E. coli
	MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.7 kDa and the accession number is A2VCV7.
TMPK-00496	MASP2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	MASP2 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.8 kDa and the accession number is A0A2K5UJY0.
TMPK-01126	MASP2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	MASP2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.6 kDa and the accession number is Q91WP0.
TMPY-06607	MFI2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MFI2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.47 kDa and the accession number is P08582-1.
TMPY-00018	METAP2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	METAP2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.3 kDa and the accession number is A0A140VJE3.
TMPK-00789	CD228 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Melanotransferrin is typically overexpressed in melanoma cells compared to other cell types - including cancer cells - and is efficiently sorted and secreted with nanovesicles, or so-called exosomes, due to its membrane-...
TMPY-01461	EMAP-II/AIMP1 Protein, Human, Recombinant (His)	Human	E. coli
	EMAP-II/AIMP1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35 kDa and the accession number is Q12904-1.
TMPY-04378	MAPKAPK3 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	The MAPKAP kinases are a group of MAP kinase substrates that are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases ...
TMPY-04410	MAP4K5 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase kinase kinase kinase 5, also known as Kinase homologous to SPS1/STE2, MAPK/ERK kinase kinase kinase 5, MEK kinase kinase 5, and MAP4K5, is a cytoplasm protein that belongs to the protein ...
TMPH-01250	MAP2K3 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that...
TMPY-04389	MAP3K8 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase kinase kinase 8, also known as Cancer Osaka thyroid oncogene, Proto-oncogene c-Cot, Serine/threonine-protein kinase cot, Tumor progression locus 2 and MAP3K8, is a cytoplasm protein that ...
TMPY-04412	Germinal Center Kinase/MAP4K2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase kinase kinase kinase 2, also known as B lymphocyte serine/threonine-protein kinase, Germinal center kinase, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, Rab8-interacting protein,...
TMPY-04425	PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	MAPKAPK5 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family. MAPKAPK5 has significant sequence homology to mitogen-activated protein kinase (MAPK)-activated...
TMPH-01692	MAPK3 Protein, Human, Recombinant (His)	Human	E. coli
	Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate...
TMPK-01452	HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPH-02994	MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (E. coli, His)	Mycobacterium paratuberculosis	E. coli
	MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 32.8 kDa and the accession number is P62039.
TMPY-03015	EMAP-II/AIMP1 Protein, Mouse, Recombinant	Mouse	E. coli
	EMAP-II/AIMP1 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is Q62386.
TMPK-01541	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPH-02786	MAPK14 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	MAPK14 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 48.6 kDa and the accession number is P47811.
TMPH-01684	MAP1LC3C Protein, Human, Recombinant (His)	Human	E. coli
	Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruits all ATG8 family members to infecting bacteria such as S.Typhimurium. May also p...
TMPK-00867	EMAP-II/AIMP1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	The potent antiangiogenic and proinflammatory protein Endothelial Monocyte Activating Polypeptide II (EMAP II) has been described as a mediator of pulmonary vascular and alveolar formation and its expression is inversely...
TMPH-02495	APMAP Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in adipocyte differentiation. APMAP Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system w...
TMPJ-01284	ERMAP Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ERMAP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 40-55 KDa and the accession number is Q96PL5.
TMPH-02077	Semaphorin-3G/SEMA3G Protein, Human, Recombinant (His & Myc)	Human	HEK293 Cells
	Semaphorin-3G/SEMA3G Protein, Human, Recombinant (His & Myc) is expressed in HEK293.
TMPY-04430	P38 gamma/MAPK12 Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	p38 gamma/MAPK12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 42.1 kDa and the accession number is P53778.
TMPK-01414	Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein, Mouse, MHC (His & Avi)	Mouse	HEK293 Cells
	Qa-1b binds a peptide (AMAPRTLLL), referred to as Qdm (for Qa-1 determinant modifier), derived from the signal sequence of murine class Ia molecules. This peptide binds with high affinity and accounts for almost all of t...
TMPH-01639	MAPK1IP1L Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	N/A. MAPK1IP1L Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 53.1 kDa and the accession number is Q8NDC0.
TMPJ-01285	ERMAP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ERMAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 16 KDa and the accession number is Q96PL5.
TMPK-00696	PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II)	Human	Baculovirus Insect Cells
	The p38 mitogen-activated protein kinase (MAPK) pathway plays an important role in cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated protein kinase (PRAK, also known as mitogen-...
TMPH-02074	Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His)	Human	E. coli
	Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-03100	PMAP-23 Protein, Pig, Recombinant (His & SUMO)	Sus scrofa (Pig)	E. coli
	Exerts antimicrobial activity against both Gram-positive and negative bacteria at concentrations of 2-16 micro molar. Its activity appears to be mediated by its ability to damage bacterial membranes. PMAP-23 Protein, Pig...
TMPK-01545	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPK-01514	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPH-02075	Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His & Myc)	Human	Baculovirus Insect Cells
	Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPY-04429	P38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.8 kDa and the accession number is P53778.
TMPH-02076	Semaphorin-3F/SEMA3F Protein, Human, Recombinant (His & Myc)	Human	HEK293 Cells
	Semaphorin-3F/SEMA3F Protein, Human, Recombinant (His & Myc) is expressed in HEK293.
TMPY-04531	P38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro	Human	Baculovirus Insect Cells
	p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68.4 kDa and the accession number is O15264.
TMPH-02995	MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (His)	Mycobacterium paratuberculosis	P. pastoris (Yeast)
	MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 28.8 kDa and the accession number is P62039.
TMPJ-01321	MAP1LC3B Protein, Human, Recombinant	Human	E. coli
	Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) is a member of the highly conserved ATG8 protein family. ATG8 proteins are present in all known eukaryotic organisms. MAP1LC3B is one of the four genes in t...
TMPY-04551	P38 delta/MAPK13 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	p38 delta/MAPK13 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68.4 kDa and the accession number is O15264.
TMPH-01693	MAP3K14 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-ka...
TMPY-03340	MAP1LC3A Protein, Human, Recombinant (His)	Human	E. coli
	LC3A, also known as MAP1LC3A, is one of the light chain subunits that function together with both MAP1A and/or MAP1B. MAP1A and MAP1B are microtubule-associated proteins that mediate the physical interactions between mic...
TMPK-01544	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPY-04572	MKK4 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is...
TMPJ-00166	SCF Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gameto...
TMPY-03425	Tau Protein, Human, Recombinant (His)	Human	E. coli
	MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are...
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METAP1 Protein, Human, Recombinant

TMPJ-00247

Species: Human

Expression System: E. coli

MAP1D Protein, Human, Recombinant (His)

TMPY-01344

Species: Human

Expression System: Baculovirus Insect Cells

MASP2 Protein, Human, Recombinant (His)

TMPK-00705

Species: Human

Expression System: E. coli

MASP2 Protein, Rat, Recombinant (E. coli, His)

TMPK-00581

Species: Rat

Expression System: E. coli

MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated

TMPK-00582

Species: Rat

Expression System: E. coli

MASP2 Protein, Cynomolgus, Recombinant (His)

TMPK-00496

Species: Cynomolgus

Expression System: E. coli

MASP2 Protein, Mouse, Recombinant (His)

TMPK-01126

Species: Mouse

Expression System: E. coli

MFI2 Protein, Human, Recombinant (His)

TMPY-06607

Species: Human

Expression System: HEK293 Cells

METAP2 Protein, Human, Recombinant (His)

TMPY-00018

Species: Human

Expression System: Baculovirus Insect Cells

CD228 Protein, Human, Recombinant (His)

TMPK-00789

Species: Human

Expression System: HEK293 Cells

EMAP-II/AIMP1 Protein, Human, Recombinant (His)

TMPY-01461

Species: Human

Expression System: E. coli

MAPKAPK3 Protein, Human, Recombinant (GST)

TMPY-04378

Species: Human

Expression System: Baculovirus Insect Cells

MAP4K5 Protein, Human, Recombinant (His & GST)

TMPY-04410

Species: Human

Expression System: Baculovirus Insect Cells

MAP2K3 Protein, Human, Recombinant (His & SUMO)

TMPH-01250

Species: Human

Expression System: E. coli

MAP3K8 Protein, Human, Recombinant (GST)

TMPY-04389

Species: Human

Expression System: Baculovirus Insect Cells

Germinal Center Kinase/MAP4K2 Protein, Human, Recombinant (His & GST)

TMPY-04412

Species: Human

Expression System: Baculovirus Insect Cells

PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST)

TMPY-04425

Species: Human

Expression System: Baculovirus Insect Cells

MAPK3 Protein, Human, Recombinant (His)

TMPH-01692

Species: Human

Expression System: E. coli

HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi)

TMPK-01452

Species: Human

Expression System: HEK293 Cells

MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (E. coli, His)

TMPH-02994

Species: Mycobacterium paratuberculosis

Expression System: E. coli

EMAP-II/AIMP1 Protein, Mouse, Recombinant

TMPY-03015

Species: Mouse

Expression System: E. coli

HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01541

Species: Human

Expression System: HEK293 Cells

MAPK14 Protein, Mouse, Recombinant (His & Myc)

TMPH-02786

Species: Mouse

Expression System: E. coli

MAP1LC3C Protein, Human, Recombinant (His)

TMPH-01684

Species: Human

Expression System: E. coli

EMAP-II/AIMP1 Protein, Mouse, Recombinant (His)

TMPK-00867

Species: Mouse

Expression System: E. coli

APMAP Protein, Mouse, Recombinant (His & Myc)

TMPH-02495

Species: Mouse

Expression System: E. coli

ERMAP Protein, Human, Recombinant (hFc)

TMPJ-01284

Species: Human

Expression System: HEK293 Cells

Semaphorin-3G/SEMA3G Protein, Human, Recombinant (His & Myc)

TMPH-02077

Species: Human

Expression System: HEK293 Cells

p38 gamma/MAPK12 Protein, Human, Recombinant

TMPY-04430

Species: Human

Expression System: Baculovirus Insect Cells

Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein, Mouse, MHC (His & Avi)

TMPK-01414

Species: Mouse

Expression System: HEK293 Cells

MAPK1IP1L Protein, Human, Recombinant (hFc)

TMPH-01639

Species: Human

Expression System: HEK293 Cells

ERMAP Protein, Human, Recombinant (His)

TMPJ-01285

Species: Human

Expression System: HEK293 Cells

PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II)

TMPK-00696

Species: Human

Expression System: Baculovirus Insect Cells

Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His)

TMPH-02074

Species: Human

Expression System: E. coli

PMAP-23 Protein, Pig, Recombinant (His & SUMO)

TMPH-03100

Species: Sus scrofa (Pig)

Expression System: E. coli

HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01545

Species: Human

Expression System: HEK293 Cells

HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi)

TMPK-01514

Species: Human

Expression System: HEK293 Cells

Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His & Myc)

TMPH-02075

Species: Human

Expression System: Baculovirus Insect Cells

p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)

TMPY-04429

Species: Human

Expression System: Baculovirus Insect Cells

Semaphorin-3F/SEMA3F Protein, Human, Recombinant (His & Myc)

TMPH-02076

Species: Human

Expression System: HEK293 Cells

p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro

TMPY-04531

Species: Human

Expression System: Baculovirus Insect Cells

MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (His)

TMPH-02995

Species: Mycobacterium paratuberculosis

Expression System: P. pastoris (Yeast)

MAP1LC3B Protein, Human, Recombinant

TMPJ-01321

Species: Human

Expression System: E. coli

p38 delta/MAPK13 Protein, Human, Recombinant (GST)

TMPY-04551

Species: Human

Expression System: Baculovirus Insect Cells

MAP3K14 Protein, Human, Recombinant (His & Myc)

TMPH-01693

Species: Human

Expression System: E. coli

MAP1LC3A Protein, Human, Recombinant (His)

TMPY-03340

Species: Human

Expression System: E. coli

HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01544

Species: Human

Expression System: HEK293 Cells

MKK4 Protein, Mouse, Recombinant (His & GST)

TMPY-04572

Species: Mouse

Expression System: Baculovirus Insect Cells

SCF Protein, Mouse, Recombinant

TMPJ-00166

Species: Mouse

Expression System: E. coli

Tau Protein, Human, Recombinant (His)

TMPY-03425

Species: Human

Expression System: E. coli

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カタログ番号	製品名
L1400	MAPK Inhibitor Library	365 compounds
	A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;
L7840	High Solubility FragLite Fragment Library	796 compounds
	The highly soluble halogenated fragment library contains 796 halogenated fragment compounds.

ライブラリー

MAPK Inhibitor Library

L1400

Compounds: 365

High Solubility FragLite Fragment Library

L7840

Compounds: 796