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TP1453 |
Tau protein (592-597), Human TFA
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Others
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Tau protein (592-597), Human (TFA) is a peptide fragment of human Tau protein. |
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T62899 |
Tau-aggregation and neuroinflammation-IN-1
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Microtubule Associated
,
NO Synthase
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Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-length tau protein aggregates. Tau-aggregation and neuroinflamma... |
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T37051 |
Tau tracer 2
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Tau tracer 2 (Pl-2620) is a specific imaging agent designed to detect and visualize Tau protein aggregates. Its primary application lies in the diagnosis of neurodegenerative diseases [1]. |
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T39660 |
Tau tracer 1
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Tau tracer 1 is a radiopharmaceutical agent designed specifically for visualizing Tau protein aggregates, commonly associated with neurodegenerative diseases. Its primary application lies in the diagnosis of these condit... |
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T6405 |
Bepotastine Besilate
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Talion,TAU 284,Bepreve,Bepotastine Beslilate |
Histamine Receptor
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Bepotastine Besilate (TAU 284) is a non-sedating and selective H1 receptor antagonist (pIC50: 5.7). |
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T39781 |
Aβ/tau aggregation-IN-1
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Aβ/tau aggregation-IN-1 is a potent inhibitor of Aβ 1-42 β-sheet formation and tau aggregation. It exhibits K D values of 160 μM and 337 μM with Aβ 1-42 and tau, respectively. Additionally, Aβ/tau aggregation-IN-1 can pe... |
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T40409 |
Tau Peptide (275-305) (Repeat 2 domain)
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Tau Peptide (275-305), also known as the R2 domain fragment, represents the second repeat unit of the microtubule-binding domain of the Alzheimer's tau peptide. Tau Peptide (275-305) is considered crucial in determining ... |
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TP1420 |
Microtubule-associated protein tau (26-44)
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Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine. |
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T63481 |
Tau-aggregation-IN-1
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Tau-aggregation-IN-1 is a dopamine D2 and D3 receptor agonist and an inhibitor of tau441 protein aggregation (IC50: 21 μM). |
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T79038 |
Tau protein aggregation-IN-1
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Tau Protein Aggregation-IN-1 (Compound 0c) serves as an inhibitor of Tau protein aggregation, applicable in research related to protein folding disorders including Alzheimer's disease, dementia, Parkinson's disease, Hunt... |
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T74811 |
tau/Aβ40 aggregation-IN-1
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Tau/Aβ40 aggregation-IN-1 (Compound 20) functions as an inhibitor for tau and Aβ 40 aggregation, exhibiting IC50 values of 1.8 μM and 1.3 μM, respectively [1]. |
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T78173 |
Aβ/tau aggregation-IN-3
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Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functional aggregation assay. This compound demonstrates anti-amyloid activ... |
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T76661 |
Acetyl-Tau Peptide (273-284) amide
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Acetyl-Tau Peptide (273-284) amide, an acetylated fragment of the Tau peptide, acts as an inhibitor to prevent significant aggregation of Ac-Aβ(25–35)-NH2. Furthermore, it serves as a model for studying the cross-interac... |
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T81031 |
tau protein/α-synuclein-IN-1
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Tau protein/α-synuclein-IN-1 is a dual inhibitor that not only impedes tau protein and α-synuclein but also reduces the development of α-syn inclusions in M17D neuroblastoma cells, making it a useful agent in the study o... |
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T17011 |
TCH-165
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Proteasome
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TCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S levels. The increase in the level of free 20S corresponds to enhanced proteolysis of IDPs. |
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T22012 |
7BIO
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FLT
,
DYRK
,
Aurora Kinase
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7-bromoindirubin-3'-oxime (7BIO) is a caspase independent nonapoptotic cell death inducer. 7BIO is an inhibitor of FLT3, DYRK1A, DYRK2, Aurora B and Aurora C kinases. |
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T1862 |
PR-619
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PR 619,2,6-Diamino-3,5-dithiocyanopyridine |
Apoptosis
,
DUB
,
Autophagy
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PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs). |
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T7530 |
PD146176
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NSC168807 |
Ferroptosis
,
Lipoxygenase
,
Autophagy
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PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology... |
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T9611 |
PF-04802367
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GSK-3
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PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay. It shows desirable central nervous system (CNS) properties and ... |
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T22118 |
NQTrp
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Microtubule Associated
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NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects. |
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T7003 |
Leucomethylene blue mesylate
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TRx0237 mesylate,TRx0237 (LMTX) mesylate,Methylene blue leuco base mesylate salt,Leucomethylene Blue Dimesylate |
Beta Amyloid
,
Microtubule Associated
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Leucomethylene blue mesylate (TRx0237 mesylate) is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia. |
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T64377 |
AGI-41998 tautomers
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Others
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AGI-41998 tautomers is a tautomerism of pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-[(2,2,2-trifluoroethyl)amino]-. pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-... |
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T6993 |
Tauroursodeoxycholate sodium
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Sodium tauroursodeoxycholate,Tauroursodeoxycholic acid sodium salt,TUDC,Sodium Tauroursodeoxycholate (TUDC) |
Apoptosis
,
ERK
,
Caspase
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Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis. |
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T13094 |
Tauroxicum
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Taurox SB |
Others
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T3211 |
Midostaurin
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N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251 |
Others
,
PKC
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PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel... |
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T11035 |
DiABZI STING agonist-1 (Tautomerism)
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diABZI STING agonist (Compound 3) |
STING
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diABZI STING agonist-1 (Tautomerism) (diABZI STING agonist (Compound 3)) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. |
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T6280 |
Enzastaurin
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LY317615 |
Apoptosis
,
PKC
,
Autophagy
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Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε. |
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T7533 |
Taurolidine
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Apoptosis
,
Others
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Antibacterial
,
Antibiotic
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Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity. |
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T3689 |
Ruboxistaurin hydrochloride
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Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride |
PKC
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Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCβI and PKCβII (IC50 values are 4.7 and 5.9 nM respectively). Sel... |
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T6278 |
Sotrastaurin
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AEB071 |
PKC
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Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ). |
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T9154 |
Sodium taurodeoxycholate hydrate
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Taurodeoxycholic acid sodium salt monohydrate |
Others
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Sodium taurodeoxycholate hydrate (Taurodeoxycholic acid sodium salt monohydrate) has been used in a study to assess the effect of submicellar concentrations of bile salts on the lipid bilayer membrane. |
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T12280 |
O-Desmethyl Midostaurin
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CGP62221,O-Desmethyl PKC412 |
Others
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O-Desmethyl Midostaurin is the active Midostaurin metabolite via cytochrome P450 liver enzyme metabolism. |
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TMIH-0552 |
Tauroursodeoxycholic Acid-d4 Sodium Salt
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Tauroursodeoxycholic Acid-d4 Sodium Salt is a deuterated compound of Tauroursodeoxycholic Acid Sodium Salt. Tauroursodeoxycholic Acid Sodium Salt has a CAS number of 14605-22-2. Tauroursodeoxycholate, also known as ursod... |
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TMIH-0038 |
3 Hydroxy Midostaurin Epimer 1-d5
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CGP52421 Epimer 1-d5 |
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3 Hydroxy Midostaurin Epimer 1-d5 is a deuterated compound of 3 Hydroxy Midostaurin Epimer 1. 3 Hydroxy Midostaurin Epimer 1 has a CAS number of 945260-14-0. |
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T12036 |
Midostaurin-D5
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PKC412-D5,CGP 41251-D5 |
Others
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Midostaurin-D5 is a deuterium labeled Midostaurin. |
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T77991 |
Glutaurine TFA
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Litoralon TFA |
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Glutaurine (Litoralon) TFA, a compound featuring glutamine and taurine residues, functions as an orally active parathyroid hormone. Originating from the oxyphil cells of the parathyroid gland, this hormone is employed in... |
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T126442 |
N-Methyltaurine
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N-Methyltaurine is a useful organic compound for research related to life sciences. The catalog number is T126442 and the CAS number is 107-68-6. |
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T3689L |
Ruboxistaurin mesylate
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LY-333531,LY333531,LY 333531,LY-333531 Mesylate |
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Ruboxistaurin is a PKC beta inhibitor. Ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Ruboxistaurin attenuates diabetic ne... |
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T16998 |
Tauroursodeoxycholate dihydrate
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Taurolite dihydrate,TUDCA dihydrate,UR 906 dihydrate |
ERK
,
Caspase
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Tauroursodeoxycholate dihydrate is an endoplasmic reticulum stress inhibitor. Tauroursodeoxycholate also inhibits ERK. Tauroursodeoxycholate significantly decreases the expression of apoptosis molecules, such as caspase-... |
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T30003 |
Ammonium acryloyldimethyltaurate
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Ammonium acryloyldimethyltaurate is a bioactive chemical. |
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T63793 |
Tauro-ω-muricholic acid sodium
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Tauro-ω-muricholic acid sodium (TωMCA sodium) is an analogue of tauro-α-muricholic acid, a bile acid of hepatic origin. Tauro-ω-muricholic acid sodium can be used as a serum marker for early onset neonatal sepsis (EOS) a... |
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T35423 |
7-oxo Staurosporine
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7-oxo Staurosporine is an antibiotic originally isolated from S. platensis with diverse biological activites. It inhibits PKC, PKA, phosphorylase kinase, EGFR, and c-Src in vitro (IC50s = 9, 26, 5, 200, and 800 nM, respe... |
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T16941 |
Stauprimide
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Others
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Stauprimide is a non-broad spectrum inhibitor that binds to the MYC transcription factor NME2 and blocks its nuclear localization in ESCs, which causes down-regulation of MYC transcription. |
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T32602 |
Laurylsarcosyltaurine
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Lauryl-sar-taurine |
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Laurylsarcosyltaurine is a surface active constituent of crab gastric juice. |
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T65644 |
N-Cyclohexyltaurine
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N-Cyclohexyltaurine is a useful organic compound for research related to life sciences. The catalog number is T65644 and the CAS number is 103-47-9. |
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T30270 |
Azidobenzamidotaurocholate
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Azido Benzamido Taurocholate is a bile acid transporter. |
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T33878 |
Pantoyltaurine
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NSC 122022,NSC 3086,NSC3086,NSC-3086 |
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Pantoyltaurine is a biochemical. |
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T69476 |
5'-Hydroxy-staurosporine
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5'-Hydroxy-staurosporine is an AMPK inhibitor with selective toxicity toward human colon tumor cells. |
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T69354 |
Enzastaurin 2HCl
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Enzastaurin 2HCl, also known as DB-102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, Enzastaurin 2HCl selectively inhibits protein ki... |
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T34788 |
Taurolithocholic acid
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Lithocholyltaurine,Lithocholic acid taurine conjugate |
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Taurolithocholic acid is a cholagogue and choleretic. |
