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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T6793 | BRD7552 | Others | |
BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression. BRD7552 increases PDX1 expression in mouse αTC cells but not βTC cells. | |||
T19853 | Dimethoxycurcumin | Veratrylcurcuminoid | Others |
Dimethoxycurcumin (Veratrylcurcuminoid) is an analog of curcumin with more metabolical stability. Dimethoxycurcumin induces epigenetic changes in leukemia cells and the expression of promoter methylated genes. | |||
T68165 | Trapencaine | ||
Trapencaine is a newly synthesized carbamate type local anesthetic that induces conformational changes in sodium channels on hypertrophic cell membranes. | |||
T61702 | SRI-37240 | ||
SRI-37240 is a powerful inhibitor of premature termination codons (PTCs). It effectively suppresses CFTR nonsense mutations and induces changes in cellular translation termination at PTCs in HEK293T cells. Additionally, ... | |||
T77556 | 2-(4-Hydroxyphenylazo)benzoicacid | ||
2-(4-Hydroxyphenylazo)benzoicacid is a spectrophotometric probe that shows changes in absorption spectra upon binding to proteins and binds to bovine serum proteins. | |||
T14994 | Coelenterazine h | 2-Deoxycoelenterazine,CLZN-h | Others |
Coelenterazine H is a synthetic derivative of coelenterazine (a light-emitting biomolecule).Coelenterazine h (CLZN-h) is more sensitive to Ca 2+ than is the native complex, thus providing a valuable tool for measuring sm... | |||
T14057 | 6-CFDA | 6-Carboxyfluorescein diacetate | Others |
6-CFDA (6-Carboxyfluorescein diacetate) is fluorescent polyanionic probe that used to measure changes in intracellular pH (pHi) and processes such as dendrimer aggregation and absorption. | |||
T2011 | RKI1313 | RKI 1313,RKI-1313 | ROCK |
RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasion. | |||
T4683 | Alovudine | 3'-Deoxy-3'-fluorothymidine | Antiviral |
Alovudine (3'-Deoxy-3'-fluorothymidine) is a marker of DNA synthesis. Alovudine is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and is a better biomarker in pancreatic cancer. | |||
T38469 | (Rac)-Z-Phe-Phe-FMK | Cathepsin L-IN-2 | Beta Amyloid , Cysteine Protease |
(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes . | |||
T9325 | 2-(2-Aminothiazole-4-yl)-2-methoxyiminoa | Others | |
2-(2-Aminothiazole-4-yl)-2-methoxyiminoa is an inhibitor of protein tyrosine phosphatases, which can lead to changes in cellular signaling pathways that affect cell behavior. | |||
T5104 | BTSA1 | Apoptosis , BCL | |
BTSA1 is a BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. | |||
T63971 | Canocapavir | ZM-H1505R | HBV |
Canocapavir (ZM-H1505R) is a novel orally available HBV coat protein modulator with antiviral activity that induces conformational changes in the linker region of the HBV core protein, and can be used for the treatment o... | |||
T22229 | Acid Yellow 36 | Metanil Yellow | Others |
Acid Yellow 36 (Metanil Yellow) is an azo dye and a pH indicator. Acid Yellow 36 changes its color from red at pH 1.2 to yellow at pH 2.3. | |||
T6760 | APS-2-79 hydrochloride | APS-2-79 HCl,APS-2-79 | MEK , MAPK |
APS-2-79 hydrochloride (APS-2-79 HCl) is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activ... | |||
T33613 | NCGC00135472 | NCGC 00135472,DRV1 (GPR32) agonist C2A,C2A,NCGC-00135472 | Others |
NCGC00135472 (DRV1 (GPR32) agonist C2A) is a human Resolvin DI receptor DRV1 agonist with pro-catabolic properties that activates the human soluble protein D1 receptor DRV1/GPR32 receptor in beta-blocker and cAMP assays ... | |||
T3126 | Bethanechol chloride | (±)-Bethanechol,Urecholine,Myocholine,Carbamyl-β-methylcholine chloride | AChR |
Bethanechol chloride (Carbamyl-β-methylcholine chloride) is a slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following ab... | |||
T22694 | CRANAD 2 | Others | |
CRANAD-2 is a difluoroboron-derivatized curcumins as near-infrared probe for in vivo detection of amyloid-beta deposits. Upon interacting with Abeta aggregates, CRANAD-2 undergoes a range of changes, which include a 70-f... | |||
T24076 | FzM1 | FzM 1,FzM-1 | Wnt/beta-catenin |
FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2) by binding to an allosteric site on intracellular loop 3 (ICL... | |||
T4364 | Aftin-4 | Aftin 4,Aftin4 | Beta Amyloid , Gamma-secretase |
Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor. Aftin-4(Aftin4) increased Aβ-1-42, but not Aβ-1-40 in mouse hipppocampus... | |||
T38013 | Sonlicromanol hydrochloride | KH 176 hydrochloride | ROS |
Sonlicromanol hydrochloride (KH176 hydrochloride) is a ROS-redox modulator that crosses the blood-brain barrier, has potential anticancer activity, improves m.3243A>G heterogeneity in iPSC-derived neurons associated with... | |||
T32681 | Leukotriene F-4 sulfone | Ltf4 sulfone | |
Leukotriene F-4 sulfone induces vascular permeability changes. | |||
T33417 | MK 410 | MK-410,MK410 | |
MK 410 is an indomethacin analogue and anti-inflammatory agent that induces changes in the immune system by inhibiting plasma neutral protease activity. | |||
T19476 | NHC-triphosphate | Others | |
NHC-triphosphate is a weak alternative substrate for the viral polymerase and changes the mobility of the product in polyacrylamide electrophoresis gels. | |||
T26395 | 6-Benzylthioinosine | 6-BT,6Benzylthioinosine,6-Bn-thioinosine | |
6-Benzylthioinosine, a broad-spectrum metabolic inhibitor, inhibits glucose uptake, decreases glycolysis and ATP concentration with minimal changes in ROS and mitochondrial respiration. | |||
T31088 | CPX-351 | Cytarabine/daunonubicin,Vyxeos,CPX 351,Daunonubicin/cytarabine | |
CPX-351 is a Liposomal-encapsulated combination of daunorubicin and cytarabine for the treatment of newly diagnosed tAML or AML with myelodysplasia-related changes (AML-MRCs). | |||
T23697 | AL-8417 | J1.090.276B,AL8417,(2R)-AL-5898 | |
AL-8417 is an enzyme inhibitor. It acting as an antioxidant, anti-inflammatory, and cytostatic agent. It also has the ability to suppress vitrectomy-induced posterior lens fiber changes. | |||
T18973 | Di-8-ANEPPS | Others | |
Di-8-ANEPPS, a voltage-sensitive dye, demonstrates shifts in both its fluorescence excitation and emission spectra in response to changes in membrane potential (Vm). | |||
T18884 | 3,3'-Dihexyloxacarbocyanine iodide | DiOC6(3) iodide | Others |
3,3'-Dihexyloxacarbocyanine iodide is a carbocyanine dye. It is used to monitor changes in mitochondrial membrane potential. | |||
T29453 | 5-Formylcytosine | ||
5-formylcytosine (5FC) is a rare base found in mammalian DNA. It participates in active DNA demethylation, changes DNA double helix structure, and reduces the transcription rate and substrate specificity of RNA polymeras... | |||
T12934 | SMAP-2 | DT-1154 | Phosphatase |
SMAP-2 is an orally bioavailable activator of phosphatase 2A (PP2A) which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. It inhibits the growth of KRAS-mutant lung cancers . | |||
TP1311 | RGD peptide (GRGDNP) (TFA) (114681-65-1 free base) | RGD peptide (GRGDNP) (TFA) | |
RGD peptide (GRGDNP) (TFA) promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. | |||
T13746 | KMG-301AM | Others | |
KMG-301AM, the acetoxy methyl esterified form of KMG-301, facilitates the acquisition of time-course and pseudo-colored images depicting the changes in mitochondrial fluorescence when stained with KMG-301. | |||
T69769 | BDP8900 | ||
BDP8900 is a potent and selective MRCK inhibitor, reducing substrate phosphorylation. BDP8900 leads to morphological changes in cancer cells along with inhibition of their motility and invasive character. | |||
T68898 | Dequalinium Bromide | ||
Dequalinium Bromide is a HIV-1 fusion inhibitor, targeting the membrane-proximal external region of Env spikes, specifically inhibiting the HIV-1 envelope-mediated membrane fusion by blocking CD4-induced conformational c... | |||
T69017 | Ibotenic acid hydrate | ||
Ibotenic acid hydrate is a neurotoxic isoxazole (similar to Kainic acid and Muscimol) found in Amanita mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitat... | |||
T26821 | BIPM | ||
BIPM is a potent inhibitor of Rho-associated protein kinase 2 (ROCK2). Exposure of SH-SY5Y cells to BIPM led to significant changes in cell migration, actin stress fibers and neurite length. BIPM significantly inhibits p... | |||
T36081 | Trehalose 6-phosphate (potassium salt hydrate) | ||
Trehalose is a natural non-reducing disaccharide found in plants, invertebrates, fungi, and bacteria.1,2In addition to roles as an energy source and stress protectant, trehalose can function as a signaling molecule.3,4Tr... | |||
T68327 | Dexnafenodone Free Base | ||
Dexnafenodone Free Base is a potent inhibitor of noradrenaline, and to a lesser degree of serotonin reuptake, induced changes in the pattern of sleep which are comparable to those of non‐sedating tricyclic antidepressant... | |||
T15180 | Duocarmycin A | Caspase | |
Duocarmycin A, an antitumor antibiotic, is a DNA alkylator and efficiently alkylates adenine N3 at the 3′ end of AT-rich sequences in the DNA. Duocarmycin A, as a chemotherapeutic agent, results in HLC-2 cells typically ... | |||
T20256 | Sorbitol, L- | L-Glucitol | |
Sorbitol, L- is a sugar alcohol. It can be obtained by the reduction of glucose, which changes the aldehyde group to a hydroxyl group. It is converted to fructose by sorbitol-6-phosphate 2-dehydrogenase. Sorbitol is an i... | |||
T80322 | Mastoparan B | ||
Mastoparan B, an antimicrobial peptide originating from the hornet Vespa, induces morphological changes in red blood cells, transforming their typical discoid shape into a serrated configuration [1]. | |||
T30242 | AY 31906 | AY-31,906 | |
AY 31906 is a high ceiling diuretic with a relative potassium-sparing effect. AY 31906 has been shown to produce significant increases in the fractional excretion of sodium and chloride in dogs at a dose that produces no... | |||
TP1105 | α-Factor Mating Pheromone, yeast (TFA) | α-Factor Mating Pheromone, yeast (TFA)(59401-28-4,FREE),Mating Factor α (TFA) | |
The alpha factor pheromone arrests yeast in the G1 phase of their cell cycle. Alpha Factor Mating Pheromone induces the expression of mating genes, changes in nuclear architecture, and polarzes growth toward the mating p... | |||
TD0052 | Fluo-3, pentasodium salt | ||
Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium c... | |||
T68600 | Enoximone sulfoxide | ||
Enoximone sulfoxide is a selective phosphodiesterase III (PDE3) inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption. Enoximone prevents the degradation... | |||
T11042 | Dihydrocytochalasin B | Others | |
Dihydrocytochalasin B (H2CB) is a cell division inhibitor that changes the morphology of cells, similar to cytochalasin B. Does not inhibit glucose transport. Dihydrocytochalasin B (H2CB) disrupts the structure of actin ... | |||
T35820 | CAY10685 | ||
CAY10685 is a cell-active analog of the lysine acetyltransferase inhibitor CPTH2 that contains an alkyne moiety for use in click chemistry reactions. Its ability to inhibit N-acetyltransferase 10 activity has been used t... | |||
TD0053 | Fluo-3, pentapotassium salt | ||
Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium c... | |||
TD0054 | Fluo-3, pentaammonium salt | ||
Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium c... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T2803 | Monocrotaline | Crotaline | TGF-beta/Smad |
Monocrotaline (Crotaline) is a pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hyp... | |||
T10023 | 1-Naphthol | NSC 9586,Nako TRB,Furro ER | Endogenous Metabolite |
1-Naphthol (Furro ER) is an excited state proton transfer (ESPT) fluorescent molecular probe for sensing thermotropic microenvironmental changes of pluronic F127 in aqueous media. | |||
T4732 | L-Carnosine | Karnozin,beta-Alanyl-L-histidine | Antioxidant , Endogenous Metabolite |
L-Carnosine (Karnozin) is is an antioxidant naturally found in skeletal muscle, brain tissue. It has the potential to suppress many of the biochemical changes that accompany aging. | |||
TN1248 | 3-Epioleanolic acid | AChR | |
3-Epioleanolic acid and oleanonic acid possess varying degrees of agonist activity on uterine smooth muscle with minor changes in the molecular structure affecting its intrinsic activity on uterine muscle. | |||
TF0083 | POPE | ||
POPE is a compound found in Escherichia coli, part of the cell membrane, and can be used to study changes in cell membrane permeability. | |||
TN7117 | Regaloside I | Others | |
Regaloside I is the monomeric component in lily. Regaloside I could be the main constituent in protecting human dermal fibroblasts from UVA-induced morphological changes [1]. | |||
T5968 | DL-Homocysteine thiolactone hydrochloride | DL-Homocysteinethiolactone hydrochloride | Endogenous Metabolite |
DL-Homocysteine thiolactone hydrochloride (DL-Homocysteinethiolactone hydrochloride) is a cysteine derivative that binds to and induces conformational changes in various plasma proteins, slowing coagulation and inducing ... | |||
TN6779 | Clausine E | Others | |
Clausine E is an inhibitor of fat mass and obesity-associated protein (FTO) demethylase activity. The binding of Clausine E to FTO was driven by positive entropy and negative enthalpy changes. | |||
T4939 | Indole-3-pyruvic acid | 3-(3-Indolyl)-2-oxopropanoic acid | Others |
Indole-3-pyruvic acid (3-(3-Indolyl)-2-oxopropanoic acid) is a compound involved in the biosynthesis of Indole-3-acetic acid, a plant hormone which plays important roles in regulating growth and responses to environmenta... | |||
T5061 | Lumichrome | 7,8-Dimethylalloxazine | Others |
Lumichrome (7,8-Dimethylalloxazine) is a natural metabolite of riboflavin. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at nanomolar concentrations. Lumichrom... | |||
T35455 | N-Nitrosodiethylamine | Diethylnitrosamine,NDEA | DNA/RNA Synthesis |
N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitroso... | |||
T2S2173 | (E)-Naringenin chalcone | Isosalipurpol,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone | Others |
Naringenin chalcone (Isosalipurpol) has antiallergic activity Naringenin chalcone suppresses asthmatic symptoms by inhibiting Th2 cytokine production from CD4 T cells. Naringenin chalcone is a potent tomato flavonoid tha... | |||
T1311 | 4-aminobenzoic acid | PABA,Vitamin H1,Vitamin Bx,para-Aminobenzoic acid | Endogenous Metabolite |
4-aminobenzoic acid (para-Aminobenzoic acid) is an organic acid with UV absorption and antifibrotic properties. When exposed to light, 4-aminobenzoic acid absorbs UV light and emits excess energy via a photochemical reac... | |||
T4719 | 1,4-D-Gulonolactone | D-Gulonic acid γ-lactone | Others , Endogenous Metabolite |
1,4-D-Gulonolactone (D-Gulonic acid γ-lactone) (also known as reduced ascorbic acid, RAA) is the substrate of the enzyme L-gulono-1,4-lactone oxidoreductase (EC 1.1.3.8), which catalyzes the last step of the biosynthesis... | |||
T8098 | γ-Hexalactone | γ-caprolactone | Others |
γ-Hexalactone (γ-caprolactone) belongs to the class of organic compounds known as gamma butyrolactones. Gamma butyrolactones are compounds containing a gamma butyrolactone moiety, which consists of an aliphatic five-memb... | |||
T26545 | Acanthoic acid | NP1302,NP 1302: NP-1302 | |
Acanthoic acid is a pimaradiene diterpene isolated from Acanthopanax koreanum with anti-inflammatory activities. Acanthoic acid downregulates LPS-induced IL-1β, IL-6 and TNF-α production in BALF, attenuates lung histopat... | |||
T15949 | Mahanimbine | AChE | |
Mahanimbine is found in the roots, leaves and stems of Murraya koenigii and is an orally active alkaloid extracted from Murraya koenigii. Bifidobacterium bifidum leaves on histopathological changes in pancreatic beta cel... | |||
TN4582 | Moracin T | c-Myc , COX | |
Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, including leucocyte infiltration, hyperplasia and cell prolife... | |||
TN4584 | Morolic acid | IL Receptor , COX , HIV Protease | |
Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediat... | |||
TN4394 | Kobophenol A | MMP , BCL , p38 MAPK , NF-κB , ROS , DNA/RNA Synthesis , CDK , JNK | |
Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell death. Kobophenol A inhibits AChE activity in a dose-depen... | |||
TN4585 | Moronic acid | HIV Protease , Antifection , HSV | |
Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186) and was modified to develop more potent anti-AIDS agents. ... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPK-01074 | CD163 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in ... | |||
TMPK-00678 | CALCA/CGRP Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Specific fragments of methylation changes in the target gene (Calca) were identified by IGV analysis. CGRP was applied to compare the effects on ASCs-T2DM morphology via phalloidin staining, proliferation through CCK-8 a... | |||
TMPJ-01210 | IL-33 Protein, Mouse, Recombinant | Mouse | E. coli |
Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identifi... | |||
TMPY-00021 | PADI4 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase f... | |||
TMPH-01286 | EEF2 Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly form... | |||
TMPH-00949 | APOLD1 Protein, Human, Recombinant (His) | Human | E. coli |
May be involved in angiogenesis. May play a role in activity-dependent changes of brain vasculature. May affect blood-brain permeability. APOLD1 Protein, Human, Recombinant (His) is expressed in E. coli expression system... | |||
TMPH-03231 | AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO) | Raphanus sativus | E. coli |
Possesses antifungal activity sensitive to inorganic cations. Induces potential changes in fungal membranes and increased K(+) efflux and Ca(2+) uptake. AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO) is express... | |||
TMPH-02330 | Zyxin Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal ... | |||
TMPH-03562 | Leukocidin-F subunit/LukF Protein, S. aureus, Recombinant (His & Myc & SUMO) | Staphylococcus aureus | E. coli |
Leukocidin causes cytotoxic changes in polymorphonuclear leukocytes. Gamma-hemolysin causes hemolysis in red blood cells. Leukocidin-F subunit/LukF Protein, S. aureus, Recombinant (His & Myc & SUMO) is expressed in E. co... | |||
TMPH-00670 | MscL Protein, E. coli O157:H7, Recombinant (B2M & His) | E. coli | E. coli |
Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. MscL Protein, E. coli O157:H7, Recombinant (B2M & His) is exp... | |||
TMPY-04934 | Serpin A3n Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
Serpina3n may represent a circulating biomarker of muscle atrophy associated with GC and, broadly, a reflection of dynamic changes in muscle mass. Serpina3n blocks endogenous increases in the activity of select skeletal ... | |||
TMPH-03691 | VSIV (strain Mudd-Summers) Glycoprotein G Protein (His & Myc) | VSIV | E. coli |
Attaches the virus to host cellular receptor, inducing clathrin-dependent endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between ... | |||
TMPH-01876 | Plexin-B1 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. ... | |||
TMPK-00983 | CD163 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in ... | |||
TMPH-00735 | LuxS Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in respon... | |||
TMPH-01875 | Plexin-B1 Protein, Human, Recombinant (His) | Human | E. coli |
Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. ... | |||
TMPH-00580 | Aquaporin Z Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid... | |||
TMPY-02544 | FANCA Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by h... | |||
TMPK-01075 | CD163 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in ... | |||
TMPY-04458 | TRIB2 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Tribbles homolog 2, also known as TRB-2, and Trib2, is a member of the protein kinase superfamily and Tribbles subfamily (Trib1, Trib2, Trib3). The identification of tribbles as regulators of signal processing systems an... | |||
TMPH-00744 | CsrA Protein, E. coli, Recombinant | E. coli | E. coli |
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress... | |||
TMPK-00710 | Claudin-4 Protein-VLP, Human, Recombinant | Human | HEK293 Cells |
Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been asso... | |||
TMPK-00526 | LRG1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Diabetic nephropathy (DN) is an important public health concern of increasing proportions and the leading cause of end-stage renal disease (ESRD) in diabetic patients. It is one of the most common long-term microvascular... | |||
TMPH-01898 | PARL Protein, Human, Recombinant (Myc) | Human | E. coli |
Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apopt... | |||
TMPH-00734 | LuxS Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in respon... | |||
TMPK-00359 | Endoglin/CD105 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis... | |||
TMPH-02103 | SRF Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with ... | |||
TMPK-01128 | LRG1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Diabetic nephropathy (DN) is an important public health concern of increasing proportions and the leading cause of end-stage renal disease (ESRD) in diabetic patients. It is one of the most common long-term microvascular... | |||
TMPH-03219 | Rabies virus (RABV) (strain India) Glycoprotein (His) | RABV | P. pastoris (Yeast) |
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb... | |||
TMPJ-01410 | LSM4 Protein, Human, Recombinant (His) | Human | E. coli |
U6 snRNA-associated Sm-like protein LSm4 (LSM4) is a member of the snRNP Sm proteins family. Sm-like proteins contain the Sm sequence motif and are thought to form a stable heteromer present in tri-snRNP particles, which... | |||
TMPH-00589 | SpoT Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response which coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme cataly... | |||
TMPH-03224 | Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (E. coli, His) | RABV | E. coli |
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb... | |||
TMPH-03222 | Rabies virus (RABV) (strain ERA) Glycoprotein (His) | RABV | E. coli |
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb... | |||
TMPK-00739 | LRP-5 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that ... | |||
TMPK-00740 | LRP-5 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that ... | |||
TMPH-03221 | Rabies virus (RABV) (strain CVS-11) Glycoprotein (His & Myc & SUMO) | RABV | E. coli |
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb... | |||
TMPH-03223 | Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (His) | RABV | Baculovirus Insect Cells |
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb... | |||
TMPY-03957 | Troponin C Protein, Human, Recombinant | Human | E. coli |
Troponin I, also known as TNNC1, is part of the troponin complex. This complex contains 3 subunits: troponin I (TnI), troponin T (TnT) and troponin C (TnC). Troponin I is the inhibitory subunit, blocking actin-myosin int... | |||
TMPJ-00601 | Apolipoprotein C-II/APOC2 Protein, Human, Recombinant (His) | Human | E. coli |
APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is ... | |||
TMPH-03220 | Rabies virus (RABV) (strain India) Glycoprotein (His & SUMO) | RABV | E. coli |
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell memb... | |||
TMPY-03117 | Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Alpha-2-glycoprotein, also known as AZGP1, belongs to the MHC class I family. It can be detected in body fluids such as serum, sweat, and seminal and breast cyst fluids. It has been shown that alpha-2-glycoprotein can st... | |||
TMPJ-00541 | CD177 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD177 is polymorphic and has at least two alleles: PRV1 and NB1. Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors. PRV1 is express... | |||
TMPH-02395 | Lassa virus (strain GA391) GPC Protein (His) | LASV | E. coli |
class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversible conformational changes induc... | |||
TMPY-03056 | LSD1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
LSD1 belongs to the flavin monoamine oxidase family. It contains 1 SWIRM domain and is a component of an RCOR/GFI/LSD1/HDAC complex. LSD1 interacts directly with GFI1 and GFI1B. LSD1 specifically removes histone H3K4me2 ... | |||
TMPH-03266 | CHI3L1 Protein, Rat, Recombinant (His) | Rat | E. coli |
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a rol... | |||
TMPJ-00914 | YY1 Protein, Human, Recombinant (His) | Human | E. coli |
Transcriptional repressor protein YY1(YY1)contains 4 C2H2-type zinc fingers and belongs to the YY transcription factor family. Multifunctional transcription factor exhibits positive and negative control on a large number... | |||
TMPJ-00790 | GSN Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
Gelsolin is a calcium-activated actin filament severing and capping protein found in many cell types and as a secreted form in the plasma of vertebrates. Gelsolin is composed of six of these domains, termed G1-6. Some re... | |||
TMPY-03615 | CSEN Protein, Human, Recombinant (His) | Human | E. coli |
KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3, also known as CSEN) is a Protein Coding gene. CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to th... | |||
TMPY-02891 | PSG6 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimes... | |||
TMPY-03653 | CTRL Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CTRL-1, also known as chymotrypsin-like protease, belongs to thepeptidase S1 family. CTRL-1 contains 1peptidase S1 domain. Its expression is increased in preeclampsia (PE). Placental-derived chymotrypsin-like protease is... | |||
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カタログ番号 | 製品名 | ||
---|---|---|---|
L1200 | Epigenetics Compound Library | 953 compounds | |
Well-chosen 953 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L2600 | Neuronal Signaling Compound Library | 2540 compounds | |
A unique collection of 2540 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L2150 | Anti-Cancer Drug Library | 3080 compounds | |
A unique collection of 3080 anticancer drugs for high throughput screening (HTS) and high content screening (HCS); | |||
L2160 | Anti-Cancer Active Compound Library | 3188 compounds | |
A unique collection of 3188 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); | |||
L2100 | Anti-Cancer Compound Library | 7234 compounds | |
A unique collection of 7234 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); | |||
L2120 | Anti-Cancer Clinical Compound Library | 2545 compounds | |
A unique collection of 2545 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L2110 | Anti-Cancer Approved Drug Library | 1779 compounds | |
A unique collection of 1779 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS); | |||
L3510 | Methylation Compound Library | 128 compounds | |
128 methylation-related compounds that can be used for high-throughput and high-content screening. | |||
L9860 | Antidepressant Compound Library | 1163 compounds | |
1163 compounds associated with depression that can be used for high-throughput and high-content screening | |||
L2180 | Anti-Cancer Compound Library Plus | 1468 compounds | |
Well-chosen 1468 anti-tumor compounds with unique structures; | |||
L7500 | Coagulation and Anticoagulation Compound Library | 144 compounds | |
A unique collection of 144 procoagulation and anticoagulation related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L9000 | Apoptosis Compound Library | 1760 compounds | |
A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening; | |||
L2501 | Human Endogenous Metabolite Compound Library Plus | 1283 compounds | |
L2500 | Human Endogenous Metabolite Library | 499 compounds | |
A collection of 499 selected human endogenous metabolites for high throughput and high content screening. | |||
L1310 | Cytoskeletal Signaling Pathway Compound Library | 759 compounds | |
A unique collection of 759 cytoskeleton-related compounds, can be used for HTS and HCS; | |||
L9830 | Anti-Parkinson's Disease Compound Library | 857 compounds | |
A unique collection of 857 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS. | |||
L8720 | Pyroptosis Compound Library | 1066 compounds | |
1066 types of active small molecules associated with pyroptosis for high-throughput and high-content screening. | |||
L9840 | Anti-Alzheimer's Disease Compound Library | 986 compounds | |
A unique collection of 986 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS. | |||
L7110 | Anti-Hypertension Compound Library | 678 compounds | |
678 hypertension-related small molecules for high-throughput and high-content screening. |