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カタログ番号	製品名	別名	ターゲット
T23384	SR 11302		DNA/RNA Synthesis
	SR 11302 is an inhibitor of activator protein-1 (AP-1).		DNA/RNA Synthesis
T10733	CDDO-EA	TP319,CDDO ethyl amide,RTA 405	Nrf2
	CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.		Nrf2
T7798	FGH10019	FGH-10019	NPC1L1 , Fatty Acid Synthase
	FGH10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM).		NPC1L1 , Fatty Acid Synthase
T23383	SR11237	SR 11237	Others , RAR/RXR
	SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.		Others , RAR/RXR
T7297	KG-501	Naphthol AS-E phosphate	Epigenetic Reader Domain
	KG-501 (Naphthol AS-E phosphate) is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 μM).		Epigenetic Reader Domain
T3460	HhAntag		Hedgehog/Smoothened , Smo
	HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway with the anti-tumor activity.		Hedgehog/Smoothened , Smo
T6113	ICG-001		Apoptosis , Epigenetic Reader Domain , Wnt/beta-catenin
	ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.		Apoptosis , Epigenetic Reader Domain , Wnt/beta-catenin
T7845	BTZO-1		Apoptosis
	BTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.		Apoptosis
TP1876L	CREBtide acetate(149155-45-3 free base)		PKA
	CREBtide acetate is a synthetic substrate for PKA (Km=3.9 μM), which is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein).		PKA
T8890	653-47 hydrochloride		Epigenetic Reader Domain
	653-47 hydrochloride is a potentiator, significantly potentiates the cAMP-response element binding protein (CREB) inhibitory activity of 666-15. It is also a very weak CREB inhibitor with IC50 of 26.3 μM.		Epigenetic Reader Domain
TP1149	HIV-1 Rev (34-50)	HIV-1 Rev 34-50,HIV-1 rev Protein (34-50)	HIV Protease
	HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) is a 17 amino acid peptide with anti-HIV-1 activity. HIV-1 Rev (34-50) is derived from the Rev-responsive element-binding domains of Rev in HIV-1.		HIV Protease
T2237	ICG001		Epigenetic Reader Domain , Wnt/beta-catenin
	ICG001 (PRI-724 isomer) antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CREB)-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coacti...		Epigenetic Reader Domain , Wnt/beta-catenin
T27083	Crebinostat		Epigenetic Reader Domain , Histone Acetyltransferase , HDAC
	Crebinostat is a potent histone deacetylase (HDAC) inhibitor, inhibiting HDAC1, HDAC2, HDAC3, and HDAC6 with IC50s of 0.7 nM, 1.0 nM, 2.0 nM, and 9.3 nM, respectively.Crebinostat increases the density of synapsin-1 punct...		Epigenetic Reader Domain , Histone Acetyltransferase , HDAC
T5437	Gefitinib-based PROTAC 3		EGFR , PROTACs
	Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a VHL ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectivel...		EGFR , PROTACs
T6832	Fatostatin hydrobromide	Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin	NPC1L1 , Fatty Acid Synthase
	Fatostatin hydrobromide (Fatostatin A HBr) ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.		NPC1L1 , Fatty Acid Synthase
T4317	PF 429242		NPC1L1 , Lipid
	PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM). It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rat...		NPC1L1 , Lipid
T24076	FzM1	FzM 1,FzM-1	Wnt/beta-catenin
	FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2) by binding to an allosteric site on intracellular loop 3 (ICL...		Wnt/beta-catenin
T6529	Halobetasol propionate	Halobetasol Propionate,Ulobetasol propionate,BMY-30056,CGP-14458	Phospholipase
	Halobetasol propionate (BMY-30056) is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses acr...		Phospholipase
T2548	Diflorasone		Glucocorticoid Receptor
	Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorti...		Glucocorticoid Receptor
T36493	CMLD-2		Apoptosis , HuR
	CMLD-2 is an inhibitor of HuR-ARE interaction (Ki: 350 nM) that competitively binds HuR protein and disrupts its interaction with adenine element-rich (ARE) mRNA targets.CMLD-2 induces apoptosis and exhibits antitumor ef...		Apoptosis , HuR
T16322	Nicodicosapent		Others
	Nicodicosapent is a fatty acid niacin conjugate. It is also an inhibitor of the sterol regulatory element-binding protein (SREBP). The sterol regulatory element-binding protein (SREBP) is a key regulator of cholesterol m...		Others
T26999	CGP64222	CGP-64222,CGP 64222
	CGP64222, a peptoid Tat/transactivation response element inhibitor, inhibits human immunodeficiency virus replication by blocking CXC-chemokine receptor 4-mediated virus entry.
T24606	PDE7 inhibitor S14	PDE7 inhibitor-S14,S14
	PDE7 inhibitor S14 is a cell-permeable PDE7 inhibitor that acts by targeting the cyclic adenosine monophosphate (cAMP)/cAMP-response element-binding protein (CREB) pathway.
T14268	Aminooxy-PEG3-methyl ester		Others
	Aminooxy-PEG3-methyl ester, a PEG-based PROTAC linker, serves as a pivotal element in the synthesis of PROTACs[1].		Others
T17031	TEI-9647		Others
	TEI-9647 is a 1α,25-dihydroxy vitamin D3-26,23-lactone (1α,25-lactone) analog and is an effective VDR/vitamin D-responsive element (DRE)-mediated genomic actions antagonist.		Others
TP1876	CREBtide
	CREBtide is a synthetic substrate for PKA (Km=3.9 µM), which is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein).
T16664	N3-PEG4-C2-NH2	PROTAC Linker 20	Others
	N3-PEG4-C2-NH2 (PROTAC Linker 20) is a PEG-based linker compound utilized for the synthesis of PROTACs. Its chemical structure enables efficient conjugation and serves as a bridging element between the target protein and...		Others
T40456	8-Bromoadenosine 5'-triphosphate tetrasodium	8-Br-ATP tetrasodium,8-Bromoadenosine 5'-triphosphate tetrasodium
	8-Bromoadenosine 5'-triphosphate tetrasodium (8-Br-ATP tetrasodium) is a tetrasodium ATP analogue, serving as a vital element for energy storage and metabolic processes in living organisms. ATP, a central component in vi...
T68594	NFAT:AP-1 inhibitor-10
	NFAT:AP-1 inhibitor-10 is a novel inhibitor of the NFAT:AP-1:DNA interaction on the ARRE-2 element, binding to DNA in a sequence-selective manner and inhibiting the transcription of the Il2 gene and several other cyclosp...
T71191	Covidcil-19
	Covidcil-19 binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE) with high affinity (Kd = 11 nM). It stabilizes the hairpin's folded state and reduces frameshifting efficiency i...
T37789	Riboflavin 5'-monophosphate (sodium salt hydrate)
	Riboflavin 5'-monophosphate (FMN) is a coenzyme that is tightly bound to enzymes catalyzing oxidation and reduction reactions in a variety of biosynthetic pathways. FMN also binds the FMN riboswitch (RFN element) on RNA ...
T79182	PPARγ agonist 8		PPAR
	PPARγ agonist 8, a compound that acts on the peroxisome proliferator-activated receptor gamma (PPARγ), has been shown to stimulate peroxisome proliferator response element (PPRE)-luciferase activity with an effective con...		PPAR
T77109	Omfiloctocog alfa
	Omfiloctocog alfa (SCT-800), a recombinant factor VIII (FVIII), is an essential protein for blood coagulation and a critical element of the fluid phase blood coagulation system. It is utilized in the research of Hemophil...
T82382	Fmoc-MMAF-OMe
	Fmoc-MMAF-OMe is a tubulin polymerization inhibitor and anticancer agent featuring an Fmoc protecting group. Its active component, MMAF, serves as the cytotoxic (ADC Cytotoxin) element in conventional antibody-drug conju...
T11798	L-692429	MK-0751	GHSR , GPCR19
			GHSR , GPCR19
T8889	653-47
	653-47 acts as a potentiator significantly enhancing the inhibitory activity of 666-15 on the cAMP-response element binding protein (CREB), while it also exhibits mild CREB inhibitory properties itself, with an IC50 valu...
T76597	Prolylserine
	Prolylserine, a dipeptide, acts as a melanogenesis inhibitor in Mel-Ab cells by reducing microphthalmia-associated transcription factor (MITF) and tyrosinase expression, inducing phosphorylation of ERK, but not affecting...
T68324	KCN1
	KCN1, a novel synthetic sulfonamide, is a HIF pathway inhibitor with potential anticancer activity in vitro and in vivo anti-pancreatic cancer activities and preclinical pharmacology. KCN1 specifically inhibited HIF repo...
T36614	DL-Sulforaphane N-acetyl-L-cysteine
	Nrf2 activation of the antioxidant response element (ARE) is central to cytoprotective gene expression against oxidative and/or electrophilic stress. Unless activated by inflammatory, environmental, or oxidative stressor...
T78055	MYC-RIBOTAC		c-Myc
	MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tethered to a small molecule that recruits and activates RNase L1. Th...		c-Myc
T21795	CRT5
	CRT5, a pyrazine benzamide, is a potent and selective PKD inhibitor. The VEGF-induced phosphorylation of three PKD substrates (IC50s = 1, 2, and 1.5 nM for PKD1, PKD2, and PKD3, respectively), histone deacetylase 5, CREB...
T65994	(6S)-N-Benzyl-6-(4-hydroxybenzyl)-8-(naphthalen-1-ylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide
	Wnt signaling is required for direct multiple biological processes and also plays key roles in the pathogenesis of various diseases. Cyclic AMP response element-binding protein (CREB) is a transcription factor that is a ...
T21812	LT175
	LT175, a dual PPARα/γ ligand, demonstrates potent insulin-sensitizing effects while exhibiting reduced adipogenic properties. This compound is an orally active partial agonist targeting PPARγ, with EC50 values of 0.22 μm...
T36593	TEI-9648
	TEI-9648, an analogue of Vitamin D3 Lactone, acts as a potent and specific antagonist to the vitamin D receptor (VDR). This compound effectively blocks the genomic actions mediated by VDR and the Vitamin D responsive ele...
T83882	XY-4
	XY-4, a derivative of 1-palmitoyl lysophosphatidic acid (1-palmitoyl LPA094) and an agonist of peroxisome proliferator-activated receptor γ (PPARγ), effectively induces reporter gene expression in RAW 264.7 macrophages h...
T36130	22(S)-hydroxy Cholesterol	22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol
	22(S)-hydroxy Cholesterol is a synthetic oxysterol and a modulator of the liver X receptor (LXR). [1] t prevents monocyte chemoattractant protein 1 (MCP-1) expression induced by the LXR agonist GW 3965 in primary hepatoc...

Compounds

SR 11302

T23384

Synonym:

Target: DNA/RNA Synthesis

CDDO-EA

T10733

Synonym: TP319,CDDO ethyl amide,RTA 405

Target: NPC1L1, Fatty Acid Synthase

SR11237

T23383

Synonym: SR 11237

Target: Others, RAR/RXR

KG-501

T7297

Synonym: Naphthol AS-E phosphate

Target: Epigenetic Reader Domain

HhAntag

T3460

Synonym:

Target: Hedgehog/Smoothened, Smo

ICG-001

T6113

Synonym:

Target: Apoptosis, Epigenetic Reader Domain, Wnt/beta-catenin

CREBtide acetate(149155-45-3 free base)

Target: Epigenetic Reader Domain

HIV-1 Rev (34-50)

TP1149

Synonym: HIV-1 Rev 34-50,HIV-1 rev Protein (34-50)

Target: Epigenetic Reader Domain, Wnt/beta-catenin

Crebinostat

T27083

Synonym:

Target: Epigenetic Reader Domain, Histone Acetyltransferase, HDAC

Gefitinib-based PROTAC 3

T5437

Synonym:

Target: EGFR, PROTACs

Fatostatin hydrobromide

T6832

Synonym: Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin

Target: NPC1L1, Fatty Acid Synthase

PF 429242

T4317

Synonym:

Target: NPC1L1, Lipid

FzM1

T24076

Synonym: FzM 1,FzM-1

Target: Wnt/beta-catenin

Halobetasol propionate

T6529

Synonym: Halobetasol Propionate,Ulobetasol propionate,BMY-30056,CGP-14458

Target: Phospholipase

Diflorasone

T2548

Synonym:

Target: Glucocorticoid Receptor

CMLD-2

T36493

Synonym:

Target: Apoptosis, HuR

Synonym: CGP-64222,CGP 64222

Target:

PDE7 inhibitor S14

T24606

Synonym: PDE7 inhibitor-S14,S14

Target:

Aminooxy-PEG3-methyl ester

Synonym: PROTAC Linker 20

Target: Others

8-Bromoadenosine 5'-triphosphate tetrasodium

T40456

Synonym: 8-Br-ATP tetrasodium,8-Bromoadenosine 5'-triphosphate tetrasodium

Target:

NFAT:AP-1 inhibitor-10

Riboflavin 5'-monophosphate (sodium salt hydrate)

DL-Sulforaphane N-acetyl-L-cysteine

(6S)-N-Benzyl-6-(4-hydroxybenzyl)-8-(naphthalen-1-ylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide

22(S)-hydroxy Cholesterol

T36130

Synonym: 22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol

Target:

カタログ番号	製品名	別名	ターゲット
T1658	Selenomethionine	DL-Selenomethionine,Seleno-DL-methionine	Amino Acids and Derivatives , Endogenous Metabolite , Autophagy
	DL-Selenomethionine (Seleno-DL-methionine) is a selenium (Se) analogue of methionine in which sulfur is replaced with the trace element selenium. Selenomethionine (SeMet) can incorporate into proteins in place of methion...
T4717	25-Hydroxycholesterol		Others , Endogenous Metabolite , HMG-CoA Reductase
	25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase and so it also plays a significant role in the in vivo regu...		Others , Endogenous Metabolite , HMG-CoA Reductase
T7033	Rosmanol		Antioxidant , COX
	Rosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and a...		Antioxidant , COX
T35709	N-acetyl-D-Lactosamine	N-Acetyllactosamine	Endogenous Metabolite
	N-acetyl-D-Lactosamine (N-Acetyllactosamine) is a disaccharide consisting of galactose and N-acetylglucose, which is an important component of various oligosaccharides and can be used as a starting material for the synth...		Endogenous Metabolite
T2915	Bardoxolone	RTA 401,CDDO	Others , Nrf2
	Bardoxolone (CDDO) is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. By supp...		Others , Nrf2
T3826	Polygalasaponin F		NF-κB , TLR , Akt , PI3K
	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...		NF-κB , TLR , Akt , PI3K
T37298	Spinacine		Endogenous Metabolite
	Spinacine has been isolated from spinach and the roots of Panax ginseng. This conformationally constrained amino acid is a structural element in certain biologically active compounds as glucagon antagonists and angiotens...		Endogenous Metabolite
TQ0163	Sagittatoside A	Icariin-A	Estrogen/progestogen Receptor
	Sagittatoside A selectively activates estrogen response element (ERE)-luciferase activity via ERα.		Estrogen/progestogen Receptor
T4S1421	Praeruptorin B	Praeruptorin D	NPC1L1 , Fatty Acid Synthase
	Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs). It can also significantly up-regulate CYP3A4 expression and activity via the PXR-mediated pathway.		NPC1L1 , Fatty Acid Synthase
T13762	Luteolin 7-sulfate		Others
	Luteolin 7-sulfate, derived from the marine plant Phyllospadix iwatensis Makino, suppresses TYR gene expression by intervening in a signaling pathway involving the cAMP-responsive element binding protein (CREB) and micro...		Others
TN4273	Isocoronarin D		Others
	Isocoronarin D is a main active ingredient for inducing death of the tested cancer cells, it possesses a wide anti-cancer capability. Isocoronarin D may have potential chemopreventive activity, it can activate antioxidan...		Others
T77289	5-O-Methylembelin
	5-O-Methylembelin is a natural isocoumarin that inhibits PCSK9 , low-density lipoprotein receptor (IDOL) , and sterol regulatory element binding protein 2 (SREBP2) mRNA expression [1] .
TN4383	Kazinol U		IL Receptor , IκB/IKK , NOS , NF-κB
	Kazinol U may have therapeutic value in delaying pancreatic β-cell destruction in type 1 diabetes by blocking the NF-ÎºB pathway in pancreatic β-cells reduces cell damage. Kazinol U shows estrogenic activity with ligand-...		IL Receptor , IκB/IKK , NOS , NF-κB
TN3539	Broussonin A		ERK , IL Receptor , IκB/IKK , NOS , NF-κB , Akt
	Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, transcriptional activity of estrogen-responsive element-lucife...		ERK , IL Receptor , IκB/IKK , NOS , NF-κB , Akt
TN6501	Isololiolide
	Isololiolide has phytotoxicity, it inhibited seedling growth of cress and barnyard grass. It also showed in vitro activity against both trypomastigote and intracellular amastigotes of Trypanosoma cruzi, with IC50 values ...

天然物製品

Selenomethionine

T1658

Synonym: DL-Selenomethionine,Seleno-DL-methionine

Target: Amino Acids and Derivatives, Endogenous Metabolite, Autophagy

25-Hydroxycholesterol

T4717

Synonym:

Target: Others, Endogenous Metabolite, HMG-CoA Reductase

Rosmanol

T7033

Synonym:

Target: Antioxidant, COX

N-acetyl-D-Lactosamine

T35709

Synonym: N-Acetyllactosamine

Target: Endogenous Metabolite

Bardoxolone

T2915

Synonym: RTA 401,CDDO

Target: NF-κB, TLR, Akt, PI3K

Spinacine

T37298

Synonym:

Target: Endogenous Metabolite

Sagittatoside A

TQ0163

Synonym: Icariin-A

Target: Estrogen/progestogen Receptor

Praeruptorin B

T4S1421

Synonym: Praeruptorin D

Target: NPC1L1, Fatty Acid Synthase

Target: IL Receptor, IκB/IKK, NOS, NF-κB

Broussonin A

TN3539

Synonym:

Target: ERK, IL Receptor, IκB/IKK, NOS, NF-κB, Akt

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-01165	CREB1 Protein, Human, Recombinant (His)	Human	E. coli
	CREB1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-02614	CREB5 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Binds to the cAMP response element and activates transcription.
TMPH-00082	DREB2C Protein, Arabidopsis thaliana, Recombinant (His)	Arabidopsis thaliana	E. coli
	Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and abscisic acid-inducible transcription. DREB2C Protein, Arabidopsis th...
TMPY-03627	CREB3L1 Protein, Human, Recombinant (aa 396-519, His)	Human	HEK293 Cells
	CREB3L1, also known as OASIS, is a cellular transcription factor synthesized as a membrane-bound precursor. It is a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation. OASIS mR...
TMPJ-00721	ZBED1 Protein, Human, Recombinant (His)	Human	E. coli
	Zinc Finger BED Domain-Containing Protein 1 (ZBED1) contains one BED-type zinc finger and is found in the cell nucleus. ZBED1 is widely expressed, highly in heart, skeletal muscle, spleen and placenta. The expression of ...
TMPJ-01241	DTD1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is...
TMPJ-01288	KLF6 Protein, Human, Recombinant	Human	E. coli
	Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by ...
TMPH-00973	DHX36 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	DHX36 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.2 kDa and the accession number is Q9H2U1.
TMPH-02142	ERR1 Protein, Human, Recombinant (GST)	Human	E. coli
	Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an importan...
TMPY-03794	CEBP gamma Protein, Human, Recombinant (His)	Human	E. coli
	CEBPG, also known as CEBP gamma, is a transcription factor which belongs to the CEBP family. Members of this family regulate viral and cellular CCAAT/enhancer element-mediated transcription. CEBP proteins contain the bZI...
TMPH-00365	Chicken anemia virus (isolate USA 26p4) Apoptin Protein (His)	CAV	E. coli
	May act as transcriptional regulator. Induces apoptosis in infected cells. Element of infectious replication cycle. Chicken anemia virus (isolate USA 26p4) Apoptin Protein (His) is expressed in E. coli expression system ...
TMPH-00366	Chicken anemia virus (isolate Germany Cuxhaven-1) Apoptin Protein (GST)	CAV	E. coli
	May act as transcriptional regulator. Induces apoptosis in infected cells. Element of infectious replication cycle. Chicken anemia virus (isolate Germany Cuxhaven-1) Apoptin Protein (GST) is expressed in E. coli expressi...
TMPH-00367	Chicken anemia virus (isolate Germany Cuxhaven-1) Apoptin Protein (His & SUMO)	CAV	E. coli
	May act as transcriptional regulator. Induces apoptosis in infected cells. Element of infectious replication cycle. Chicken anemia virus (isolate Germany Cuxhaven-1) Apoptin Protein (His & SUMO) is expressed in E. coli e...
TMPH-01550	Interferon kappa/IFNK Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon-stimulated response element signaling pa...
TMPH-01461	HNRNPA3 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Plays a role in cytoplasmic trafficking of RNA. Binds to the cis-acting response element, A2RE. May be involved in pre-mRNA splicing. HNRNPA3 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression sys...
TMPY-04468	STK16 Protein, Human, Recombinant (His & NusA)	Human	E. coli
	Serine/threonine-protein kinase 16, also known as myristoylated and palmitoylated serine/threonine-protein kinase, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, MPSK1 and STK16, is a membrane protein that is...
TMPH-01281	ELAVL3 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	RNA-binding protein that binds to AU-rich element (ARE) sequences of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3. May be involved in neuronal differentiation and maintenance. Plays a role in ...
TMPH-00738	TetR5 Protein, E. coli, Recombinant (His)	E. coli	E. coli
	TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline re...
TMPH-00039	Single-strand DNA-binding protein Protein, Agrobacterium fabrum, Recombinant (His & Myc)	Agrobacterium fabrum	E. coli
	Involved in DNA transformation; mediates the nuclear uptake of single-stranded DNA copies of the transferred DNA (T-DNA) element. Binds single-stranded but not double-stranded DNA regardless of nucleotide sequence compos...
TMPH-03713	ELAVL4 Protein, Xenopus tropicalis, Recombinant (His)	Xenopus tropicalis	E. coli
	RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in th...
TMPH-01798	Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO)	Human	E. coli
	Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream...
TMPH-01864	PITHD1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Promotes megakaryocyte differentiation by up-regulating RUNX1 expression. Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome...
TMPH-01799	Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO)	Human	E. coli
	Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream...
TMPH-00737	TetR2 Protein, E. coli, Recombinant (His & SUMO)	E. coli	E. coli
	TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline re...
TMPJ-00689	EIF1B Protein, Human, Recombinant (His)	Human	E. coli
	Eukaryotic Translation Initiation Factor 1B (EIF1B) is an element of a complex involved in recognition of the initiator codon during the scanning process. Translation is also initiated by the function of EIF1B in regulat...
TMPH-03711	PPAR gamma Protein, Xenopus laevis, Recombinant (His)	Xenopus laevis	E. coli
	Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcript...
TMPJ-00886	ATF1 Protein, Human, Recombinant (His)	Human	E. coli
	Cyclic AMP-dependent transcription factor ATF-1(ATF1) which contains 1 bZIP (basic-leucine zipper) domain and 1 KID (kinase-inducible) domain, belongs to the bZIP family. It influences cellular physiologic processes by r...
TMPJ-01080	HSF2 Protein, Human, Recombinant (His)	Human	E. coli
	Heat Shock Factor Protein 2 (HSF2) belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. In higher eukaryotes, HSF is unable to bind to t...
TMPH-01796	NR4A1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B tr...
TMPH-01463	HNRNPL Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleop...
TMPH-00077	IAA17 Protein, Arabidopsis thaliana, Recombinant (His & Myc)	Arabidopsis thaliana	E. coli
	Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response fac...
TMPK-01309	LRRC15 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge ...
TMPH-02103	SRF Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with ...
TMPH-01699	SMAD2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in t...
TMPY-03496	EBAG9 Protein, Human, Recombinant (His)	Human	E. coli
	RCAS1, also known as EBAG9, is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. RCAS1 gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen ...
TMPH-02613	ATF-5 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific respo...
TMPU-00003	STAT2 Protein, Human, Recombinant (His)	Human	E. coli
	Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading...
TMPK-01380	LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)	Cynomolgus,Rhesus	HEK293 Cells
	The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge ...
TMPK-01070	LRRC15 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge ...
TMPK-00338	LRRC15 Protein, Human, Recombinant (His & Avi)	Human	CHO Cells
	The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation. LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge ...
TMPJ-00913	MPZ Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Myelin Protein P0 (MPZ) is a single-pass type I membrane glycoprotein which belongs to the myelin P0 protein family. MPZ contains one Ig-like V-type (immunoglobulin-like) domain, absent in the central nervous system. MPZ...
TMPH-00028	Adeno-associated virus 2 (isolate Srivastava/1982) Rep78 Protein (His & MBP)	AAV-2	E. coli
	Plays an essential role in the initiation of viral DNA synthesis. Binds specifically to an inverted terminal repeat element (ITR) on the 3' and 5' ends of the viral DNA, where it cleaves a site specifically to generate a...
TMPY-03606	ECSIT Protein, Human, Recombinant (His)	Human	E. coli
	ECSIT is an adapter protein of the toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Activation of NF-kappaB as a consequence of signaling through the Toll and IL-...
TMPH-00541	Epstein-Barr virus (strain AG876) LMP1 Protein (His & Myc)	EBV	E. coli
	Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several s...
TMPY-02893	NT5C3A/NT5C3 Protein, Human, Recombinant	Human	E. coli
	NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded prot...
TMPY-03615	CSEN Protein, Human, Recombinant (His)	Human	E. coli
	KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3, also known as CSEN) is a Protein Coding gene. CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to th...
TMPH-00542	Epstein-Barr virus (strain Raji) LMP1 Protein (His)	EBV	P. pastoris (Yeast)
	Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several s...
TMPY-02444	ATF2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-ac...
TMPY-00140	ABP1/AOC1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putres...
TMPJ-00271	SMAD3 Protein, Human, Recombinant (His & Flag)	Human	E. coli
	Mothers against decapentaplegic homolog 3(SMAD3) is a cytoplasm protein which belongs to the dwarfin/SMAD family. Smad proteins undergo rapid nuclear translocation upon stimulation by transforming growth factor and in so...
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CREB1 Protein, Human, Recombinant (His)

TMPH-01165

Species: Human

Expression System: E. coli

CREB5 Protein, Mouse, Recombinant (His)

TMPH-02614

Species: Mouse

Expression System: E. coli

DREB2C Protein, Arabidopsis thaliana, Recombinant (His)

TMPH-00082

Species: Arabidopsis thaliana

Expression System: E. coli

CREB3L1 Protein, Human, Recombinant (aa 396-519, His)

TMPY-03627

Species: Human

Expression System: HEK293 Cells

ZBED1 Protein, Human, Recombinant (His)

TMPJ-00721

Species: Human

Expression System: E. coli

DTD1 Protein, Human, Recombinant (His)

TMPJ-01241

Species: Human

Expression System: HEK293 Cells

KLF6 Protein, Human, Recombinant

TMPJ-01288

Species: Human

Expression System: E. coli

DHX36 Protein, Human, Recombinant (His & Myc)

TMPH-00973

Species: Human

Expression System: E. coli

ERR1 Protein, Human, Recombinant (GST)

TMPH-02142

Species: Human

Expression System: E. coli

CEBP gamma Protein, Human, Recombinant (His)

TMPY-03794

Species: Human

Expression System: E. coli

Chicken anemia virus (isolate USA 26p4) Apoptin Protein (His)

TMPH-00365

Species: CAV

Expression System: E. coli

Chicken anemia virus (isolate Germany Cuxhaven-1) Apoptin Protein (GST)

TMPH-00366

Species: CAV

Expression System: E. coli

Chicken anemia virus (isolate Germany Cuxhaven-1) Apoptin Protein (His & SUMO)

TMPH-00367

Species: CAV

Expression System: E. coli

Interferon kappa/IFNK Protein, Human, Recombinant (His & SUMO)

TMPH-01550

Species: Human

Expression System: E. coli

HNRNPA3 Protein, Human, Recombinant (His & Myc)

TMPH-01461

Species: Human

Expression System: E. coli

STK16 Protein, Human, Recombinant (His & NusA)

TMPY-04468

Species: Human

Expression System: E. coli

ELAVL3 Protein, Human, Recombinant (His)

TMPH-01281

Species: Human

Expression System: P. pastoris (Yeast)

TetR5 Protein, E. coli, Recombinant (His)

TMPH-00738

Species: E. coli

Expression System: E. coli

Single-strand DNA-binding protein Protein, Agrobacterium fabrum, Recombinant (His & Myc)

TMPH-00039

Species: Agrobacterium fabrum

Expression System: E. coli

ELAVL4 Protein, Xenopus tropicalis, Recombinant (His)

TMPH-03713

Species: Xenopus tropicalis

Expression System: E. coli

Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO)

TMPH-01798

Species: Human

Expression System: E. coli

PITHD1 Protein, Human, Recombinant (His & Myc)

TMPH-01864

Species: Human

Expression System: E. coli

Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO)

TMPH-01799

Species: Human

Expression System: E. coli

TetR2 Protein, E. coli, Recombinant (His & SUMO)

TMPH-00737

Species: E. coli

Expression System: E. coli

EIF1B Protein, Human, Recombinant (His)

TMPJ-00689

Species: Human

Expression System: E. coli

PPAR gamma Protein, Xenopus laevis, Recombinant (His)

TMPH-03711

Species: Xenopus laevis

Expression System: E. coli

ATF1 Protein, Human, Recombinant (His)

TMPJ-00886

Species: Human

Expression System: E. coli

HSF2 Protein, Human, Recombinant (His)

TMPJ-01080

Species: Human

Expression System: E. coli

NR4A1 Protein, Human, Recombinant (His & Myc)

TMPH-01796

Species: Human

Expression System: E. coli

HNRNPL Protein, Human, Recombinant (His & SUMO)

TMPH-01463

Species: Human

Expression System: E. coli

IAA17 Protein, Arabidopsis thaliana, Recombinant (His & Myc)

TMPH-00077

Species: Arabidopsis thaliana

Expression System: E. coli

LRRC15 Protein, Canine, Recombinant (His)

TMPK-01309

Species: Canine

Expression System: HEK293 Cells

SRF Protein, Human, Recombinant (His)

TMPH-02103

Species: Human

Expression System: P. pastoris (Yeast)

SMAD2 Protein, Human, Recombinant (His & SUMO)

TMPH-01699

Species: Human

Expression System: E. coli

EBAG9 Protein, Human, Recombinant (His)

TMPY-03496

Species: Human

Expression System: E. coli

ATF-5 Protein, Mouse, Recombinant (His & Myc)

TMPH-02613

Species: Mouse

Expression System: E. coli

STAT2 Protein, Human, Recombinant (His)

TMPU-00003

Species: Human

Expression System: E. coli

LRRC15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

TMPK-01380

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

LRRC15 Protein, Mouse, Recombinant (His)

TMPK-01070

Species: Mouse

Expression System: HEK293 Cells

LRRC15 Protein, Human, Recombinant (His & Avi)

TMPK-00338

Species: Human

Expression System: CHO Cells

MPZ Protein, Human, Recombinant (His)

TMPJ-00913

Species: Human

Expression System: HEK293 Cells

Adeno-associated virus 2 (isolate Srivastava/1982) Rep78 Protein (His & MBP)

TMPH-00028

Species: AAV-2

Expression System: E. coli

ECSIT Protein, Human, Recombinant (His)

TMPY-03606

Species: Human

Expression System: E. coli

Epstein-Barr virus (strain AG876) LMP1 Protein (His & Myc)

TMPH-00541

Species: EBV

Expression System: E. coli

NT5C3A/NT5C3 Protein, Human, Recombinant

TMPY-02893

Species: Human

Expression System: E. coli

CSEN Protein, Human, Recombinant (His)

TMPY-03615

Species: Human

Expression System: E. coli

Epstein-Barr virus (strain Raji) LMP1 Protein (His)

TMPH-00542

Species: EBV

Expression System: P. pastoris (Yeast)

ATF2 Protein, Human, Recombinant (His & GST)

TMPY-02444

Species: Human

Expression System: Baculovirus Insect Cells

ABP1/AOC1 Protein, Human, Recombinant (His)

TMPY-00140

Species: Human

Expression System: HEK293 Cells

SMAD3 Protein, Human, Recombinant (His & Flag)

TMPJ-00271

Species: Human

Expression System: E. coli

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カタログ番号	製品名
L1200	Epigenetics Compound Library	953 compounds
	Well-chosen 953 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs;
L5100	Fluorochemical Library	574 compounds
	A unique collection of 574 fluorochemicals that can be used for high through-put screening (HTS) and high content screening (HCS);
L6750	PBCRBS Traditional Chinese Medicine Compound Library	580 compounds
	A unique collection of 580 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis.

ライブラリー

Epigenetics Compound Library

L1200

Compounds: 953

Fluorochemical Library

L5100

Compounds: 574

PBCRBS Traditional Chinese Medicine Compound Library

L6750

Compounds: 580