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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T38117 | WSP-5 | Washington State Probe-5,WSP-5 | |
Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-5 is a reactive disulfide-... | |||
T7414 | ARS-853 | Apoptosis , Raf , Ras | |
ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells | |||
T10826 | CK-666 | HIV Protease , Microtubule Associated | |
CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex. It binds to the Arp2/3 complex, stabilizes the inactive state of the complex, blocking the movement of the Arp2 and Arp3 subunits into the act... | |||
T8369 | Adagrasib | MRTX849 | Ras |
Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib ... | |||
T22675 | Co 102862 | V 102862 | Others , Sodium Channel |
Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies. | |||
T12519 | Sodium metatungstate | POM-1,Sodium polyoxotungstate | Phosphatase |
Sodium metatungstate (Sodium polyoxotungstate) is a potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase)(Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3 and NTPDase 2 respecti... | |||
T64838 | Tetrabutylphonium decatungstate | ||
Tetrabutylphonium decatungstate is a useful organic compound for research related to life sciences and the catalog number is T64838. | |||
T64830 | Tetrapotassium decatungstate | ||
Tetrapotassium decatungstate is a useful organic compound for research related to life sciences and the catalog number is T64830. | |||
T64579 | Tetrabutylammonium decatungstate | ||
Tetrabutylammonium decatungstate is a useful organic compound for research related to life sciences and the catalog number is T64579. | |||
T64775 | Sodium tungstate(VI) | ||
Sodium tungstate(VI) is a useful organic compound for research related to life sciences and the catalog number is T64775. | |||
T33791 | Oleyl myristate | ||
Oleyl myristate is a bioactive chemical. | |||
T30154 | Ascorbyl myristate | Ascorbyl monomyristate,6-tetradecanoate,L-Ascorbic acid | |
Ascorbyl myristate is a bioactive chemical. | |||
T80552 | Prostate Specific Antigen Substrate | ||
Prostate Specific Antigen Substrate is a fluorescent substrate specific to prostate specific antigen (PSA) and facilitates the detection of PSA enzymatic activity [1]. | |||
T23189 | Prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] | Others | |
Prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] is a peptide with the sequence H2N-Ala-Thr-Gly-Gly-Tyr-Arg-OH, MW= 623.66. | |||
T5370 | DTT | DL-Dithiothreitol | Others |
DTT (DL-Dithiothreitol) is a reagent for maintaining SH groups in the reduced state. | |||
T13925 | THS-044 | N-[2-Nitro-4-(Trifluoromethyl)phenyl]morpholin-4-Amine,N-Morpholino-2-nitro-4-(trifluoromethyl)aniline | HIF |
THS-044 (N-[2-Nitro-4-(Trifluoromethyl)phenyl]morpholin-4-Amine) binding stabilizes the HIF2α PAS-B folded state with a kd of 2 μM and regulates HIF2 activity in endogenous and clinical settings. | |||
T26287 | Transcainide | R54718,R 54718,R-54718 | Sodium Channel |
Transcainide(R 54718), a new lidocaine analog, is an orally active antiarrhythmic agent.Transcainide blocks the open state of BTX-activated sodium channels in bovine heart and rat skeletal muscle. | |||
T21769L | β-Pompilidotoxin Acetate | β-Pompilidotoxin Acetate(216064-36-7 Free base) | Sodium Channel |
β-Pompilidotoxin Acetate is a wasp venom peptide. β-Pompilidotoxin Acetate can slow sodium channel inactivation and increase steady-state sodium current in cells. | |||
T21339 | Peramivir | RWJ 270201,BCX1812,BCX 1812,RWJ270201 | |
Peramivir, a neuraminidase inhibitor, acts as a transition-state analogue inhibitor of influenza neuraminidase and thereby preventing new viruses from emerging from infected cells. It is used as an antiviral drug for the... | |||
T15711 | Larazotide acetate | Gap Junction Protein | |
Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state. | |||
T8700 | TKIM | Potassium Channel | |
TKIM is a TWIK-related potassium channel 1 (TREK-1) inhibitor, binding to the pocket of the intermediate (IM) state of TREK-1. | |||
T19352 | HBC620 | Others | |
HBC620 shows brightly fluoresced in the Pepper bound state and can be visualize RNA dynamics in live cells. HBC620 is a HBC-like fluorophore. | |||
T8684 | Sotorasib | AMG-510 | Ras |
Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C. Sotorasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Sotorasib ... | |||
T2635 | Org 27569 | Cannabinoid Receptor | |
Org 27569, an allosteric modulator of cannabinoid CB1 receptor, can induce a CB1 receptor state that is characterized by decreased inverse agonist affinity and enhanced agonist affinity. | |||
T8711 | PF-05186462 | PF-05150122 | Sodium Channel |
PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5. | |||
T29037 | UC-781 | NSC 675186,UC781,UC 781 | Antiviral , HIV Protease |
UC-781 (NSC-675186) is a potent and selective inhibitor of human immunodeficiency virus HIV-1 non-nucleoside reverse transcriptase (NNRTI) I with a C50 value of 5 nM.UC-781 exhibits both antiviral activity and drug resis... | |||
T2169 | Zebularine | NSC309132,4-Deoxyuridine | DNA Methyltransferase , Autophagy |
Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor. Acts as a transition state analog inhibitor of cytidine deaminase by binding to the active size as covalent hydrates. It also inhibits cytidine deaminase (Ki: 2... | |||
T33816 | Ordopidine | ACR-325,ACR 325,ACR325 | Dopamine Receptor |
Ordopidine (ACR325) is a dopaminergic stabilizer that suppresses psychostimulant-induced hyperactivity disorder and stimulates behavior during inactivity. Ordopidine acts as a dopamine D2 receptor antagonist in vitro and... | |||
T24754 | Hh-Ag1.5 | SAG-1.5,SAG1.5,SAG 1.5 | Hedgehog/Smoothened |
Hh-Ag1.5 (SAG-1.5) is a potent Hedgehog (Hh) agonist (EC50: 1 nM) and Smoothened (Smo) receptor agonist, with an EC50 of 1 nM and Ki values between 0.5 and 2.3 nM for Smo. Hh-Ag1.5-mediated reprogramming breaks the quies... | |||
T2408 | Ostarine | MK-2866,GTX-024,Enobosarm | Androgen Receptor |
Ostarine (MK-2866) is a non-steroidal agent with anabolic activity. Selective androgen receptor modulator (SARM) GTx-024 is designed to work like testosterone, thus promoting and/or maintaining libido, fertility, prostat... | |||
T9972 | Divarasib | GDC-6036 | Ras |
Divarasib (GDC-6036) (GDC-6036) is an investigational, oral, high-potency and selective KRAS G12C inhibitor with an IC50 of < 0.01 μM. Divarasib irreversibly locks KRAS G12C oncoprotein in an inactive state and inhibi... | |||
T13983 | 0990CL | cAMP , Others | |
0990CL is an effective heterotrimer Gαi subunit specific inhibitor, which can interact with purified Go± in GDP-bound state, and can block α2AR mediated cAMP regulation. In the cell model, low concentration of 0990CL cou... | |||
T37807 | JTV 519 fumarate | ||
Ryanodine receptor (RyR) inhibitor; stabilizes RyR2 in a closed conformation. Exhibits antiarrhythmic and cardioprotective properties in vivo. Hunt et al (2007) K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]r... | |||
T14884 | CBR-5884 | Others , Dehydrogenase | |
CBR-5884 is an selective, active of phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with h... | |||
T70543 | U 92163 | ||
U 92163 is synthetic peptidic transition state analog inhibitor that was used to determine the crystallographic structure of the protease from human immunodeficiency virus type 2. | |||
T24902 | TROX-1 | TROX1,TROX 1 | |
TROX-1 is the activation state-dependent Cav2 channel antagonist. | |||
T25184 | Butalamine | Butalamina | |
Butalamine is a vasodilator (peripheral) with local anesthetic effects. It suppresses state 3 respiration and decreases ADP/O in the rat liver. | |||
T34665 | SN-1 | SN1 | |
SN-1 is a zinc chelator which increases steady-state expression level of A3G in the presence of Vif. | |||
T14992 | Raxatrigine hydrochloride | GSK-1014802 hydrochloride,CNV1014802 (hydrochloride) | Others |
Raxatrigine hydrochloride is a state-dependent sodium channel blocker and a Nav1.7 sodium channel inhibitor. | |||
T30601 | BTC | ||
BTC is a human G-quadruplexes regulator, inducing dynamic transitions between the ensembles of unfolded conformations to the folded state in G-quadruplexes, altering the rod shaped DNA sequences into globular quadruplexe... | |||
T71239 | CNV-2197944 | ||
CNV-2197944 is a novel, small molecule, state-dependent calcium channel blocker, designed to selectively inhibit highly active Cav2.2 channels. | |||
T36587 | 8-Aminopyrene-1,3,6-trisulfonic Acid sodium salt | Others | |
8-Aminopyrene-1,3,6-trisulfonic acid (APTS) is an anionic fluorescent dye with excitation/emission spectra of 425/503 nm, respectively. It forms a ground state complex with viologen-type quenchers, inducing a red-shift i... | |||
T25184L | Butalamine HCl | LA 1221,Hemotrope,Butalamine hydrochloride,Adrevil | |
Butalamine HCl is a vasodilator (peripheral) with local anesthetic effects. It suppresses state 3 respiration and decreases ADP/O in the rat liver. | |||
T10374 | ARS-1323-alkyne | Ras | |
ARS-1323-alkyne is a switch-II pocket (S-IIP) inhibitor and a conformational specific chemical reporter of KRASG12C nucleotide state in living cells. | |||
T71191 | Covidcil-19 | ||
Covidcil-19 binds to the revised attenuator hairpin structure of the SARS-CoV-2 frameshifting element (FSE) with high affinity (Kd = 11 nM). It stabilizes the hairpin's folded state and reduces frameshifting efficiency i... | |||
T30827 | Cgp 33304 | Cgp-33304,Cgp33304 | |
CGP 33304 is a dual leukotriene receptor antagonist and phospholipase A2 inhibitor. It prevents hypoxia secondary to bronchial constriction induced by leukotriene in a shocking state. | |||
T25896 | Octicidine | ASOHO | |
Octicidine is derived from phaseolotoxin by the removal of C-terminal dipeptide. It is a transition state analog that irreversibly suppresses ornithine carbamoyltransferase. | |||
T7352L | Pridopidine hydrochloride | ASP2314 HCl,Pridopidine HCl,FR310826,ASP-2314 hydrochloride | |
Pridopidine Hydrochloride is a dopaminergic stabilizer that has been shown to improve a variety of neurological and psychiatric disorders, including Huntington's disease. Pridopidine Hydrochloride stabilizes psychomotor ... | |||
T23506 | Viomycin | Others | |
Viomycin is a member of the tuberactinomycin family of antibiotics. Viomycin also inhibits group I intron splicing and prokaryotic protein synthesis. Freezes bacterial ribosomes in either the pre- or post-translational s... | |||
T81459 | Pinacyanol iodide | ||
Pinacyanol iodide, a fluorescent cyanine dye, exhibits ultrafast excited-state isomerization [1]. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T20005 | Isopropyl myristate | IPM,Isomyst,HSDB 626,FEMA No. 3556,NSC 406280,Stepan D-50 | Others |
Isopropyl myristate (IPM) is the isopropyl alcohol and myristic acid ester. | |||
T8040 | Cholesterol myristate | Cholesteryl myristate,Cholesteryl tetradecanoate | Others , Potassium Channel , GABA Receptor , Endogenous Metabolite , AChR |
Cholesterol Myristate (Cholesteryl Myristate) is a natural steroid found in traditional Chinese medicine that interacts with various ion channels, including the GABAA receptor, nicotinic acetylcholine receptor, and the i... | |||
TN6901 | Methyl myristate | methyl tetradecanoate | Others |
Methyl myristate (methyl tetradecanoate) is a natural product. | |||
TN6994 | Ethyl Myristate | ||
Ethyl Myristate is a natural product. | |||
TQ0198 | Phorbol 12-myristate 13-acetate | PMA | NF-κB , S1P Receptor , PKC |
Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB. Phorbol 12-myristate 13-acetate induces THP1 cell differentiation. | |||
TN4546 | Methyl isocostate | Others | |
Methyl isocostate is a natural product for research related to life sciences. The catalog number is TN4546 and the CAS number is 132342-55-3. | |||
T10023 | 1-Naphthol | NSC 9586,Nako TRB,Furro ER | Endogenous Metabolite |
1-Naphthol (Furro ER) is an excited state proton transfer (ESPT) fluorescent molecular probe for sensing thermotropic microenvironmental changes of pluronic F127 in aqueous media. | |||
T4884 | Alpha-D-glucose | α-D-Glucose,alpha-Glucose,α-Dextrose | Others , Endogenous Metabolite |
alpha-D-glucose (α-Dextrose) is a primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutri... | |||
T0887 | D-Glucose | Dextrose,Glucopyranose,Grape sugar,D(+)-Glucose | Endogenous Metabolite |
D-Glucose (Glucopyranose) is a primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient... | |||
T67685 | 4-Methylumbelliferyl-β-D-xylopyranoside | 4-Methylumbelliferyl-β-D-xyloside | |
4-Methylumbelliferyl-β-D-xylopyranoside (4-Methylumbelliferyl-β-D-xyloside) exhibits bursting steady-state kinetics in biological experiments, which supports the conclusion of rapid hydrolysis of the glycosidic bond of t... | |||
T8733 | Antrodin A | camphorataanhydride A | Others |
Antrodin A (camphorataanhydride A) (AdA) is one of the main active ingredients in the solid-state fermented A. camphorata mycelium. It protects the liver from alcohol damage by improving the antioxidant and anti-inflamma... | |||
T2910 | Flavonol | 3-Hydroxyflavone,3-HF,Flavon-3-ol,3-Hydroxy-2-phenylchromone | Others , Endogenous Metabolite |
Flavonol (3-Hydroxyflavone) is a member of the class of compounds known as flavonols. 3-hydroxyflavone can be found in a number of food items such as brassicas, pomegranate, red raspberry, and fenugreek. 3-hydroxyflavone... | |||
T38108 | Fulvic Acid | Antioxidant , PDE | |
Fulvic Acid is a natural product of humus produced by microorganisms in soil, sediment or aquatic environments. Fulvic acid is a phenolic acid and fungal metabolite isolated from Penicillium for the first time. Fulvic Ac... | |||
TN1163 | 2'-Hydroxychalcone | Others | |
2'-Hydroxychalcone is a drug synthesis intermediate for the synthesis of flavonoids. 2'-Hydroxychalcone loaded in nanoemulsion showed fungicidal activity against Coccidioides parapsilosis in Danio rerio model.2'-Hydroxyc... | |||
T38395 | Pyrrole-2-carboxaldehyde | ||
Pyrrole-2-carboxaldehyde exhibits distinctive vibrational and electronic properties which serve to validate its dimeric state in the solid phase and monomeric state in the solution phase. | |||
T19565 | Streptolysin O | Others | |
Streptolysin O causes both lysis of cells and cardiotoxicity. Streptolysin O is widely used for the controlled permeabilization of cell membranes. Streptolysin O exists in two forms, a reduced active state and an oxidize... | |||
TN1912 | Marinobufogenin | Marinobufagenin | ATPase , EGFR |
Marinobufagenin, a cardiotonic steroid, its increased concentrations are important in the cardiac disease and oxidant stress state seen with renal failure. | |||
TN3844 | Didrovaltrate | Calcium Channel | |
Didrovaltrate shows cytotoxic against human cancer cell lines. Didrovaltrate blocks I(Ca-L) in a concentration-dependent manner and probably inhibits I(Ca-L) in its inactive state, which may contribute to its cardiovascu... | |||
T71750 | Quinolactacin A1 | ||
Quinolactacin A1, a powerful acetylcholinesterase (AChE) inhibitor, originates from the solid-state fermentation of Penicillium citrinum 90648. It is utilized in Alzheimer's disease research. | |||
TN2830 | 26-Nor-8-oxo-alpha-onocerin | Others | |
26-Nor-8-oxo-alpha-onocerin can promote the osteoblast proliferation rate, the effect is time-dependent,concentration-dependent and differentiation state-dependent. | |||
TN3541 | Broussonin E | ERK , p38 MAPK , TNF , JAK , STAT | |
Broussonin E could suppress inflammation by modulating macrophages activation state via inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathway, and can be further developed as a promising drug for the... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPH-03062 | Norovirus (strain Human/NoV/United States/Norwalk/1968/GI) VP1 Protein (Flag & Myc) | Norwalk virus | HEK293 Cells |
Capsid protein self assembles to form an icosahedral capsid with a T=3 symmetry, about 38 nm in diameter, and consisting of 180 capsid proteins. A smaller form of capsid with a diameter of 23 nm might be capsid proteins ... | |||
TMPH-03419 | Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) VP6 Protein (His) | RV-A | E. coli |
Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) VP6 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 50.9 kDa and the accession number is P03530. | |||
TMPY-02956 | Apolipoprotein L/APOL1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney... | |||
TMPY-03758 | Vaccinia Virus B18R/B19R Protein (His) | VACV | Baculovirus Insect Cells |
B18R is a type I interferon (IFN)-binding protein, which is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus. It is also known as B19R in the Copenhagen strain of Vaccinia. ... | |||
TMPJ-01065 | Noggin/NOG Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal pept... | |||
TMPH-00522 | Recombinase cre Protein, Enterobacteria phage P1, Recombinant (His & Myc) | Escherichia phage P1 | E. coli |
Catalyzes site-specific recombination between two 34-base-pair LOXP sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state. | |||
TMPJ-00815 | FBPase1 Protein, Human, Recombinant (His, E. coli) | Human | E. coli |
Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and... | |||
TMPY-03981 | CPLX3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CPLX3, also known as complexin 3, belongs to the complexin/synaphin family. As a SNARE-binding protein, complexin (CPX), can act either as a facilitator or as an inhibitor of membrane fusion, constituting a controversial... | |||
TMPH-02198 | TXNRD2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling. | |||
TMPH-02163 | Syncytin-1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through ... | |||
TMPY-02805 | GNGT1 Protein, Human, Recombinant (His) | Human | E. coli |
GNGT1 is a subunit of transducin. Heterotrimeric G proteins consist of alpha, beta, and gamma subunits. They are membrane-bound GTPases that are linked to 7-TM receptors. They function as signal transducers for the 7-tra... | |||
TMPH-01671 | Human metapneumovirus (strain CAN97-83) Fusion glycoprotein F0 (His & SUMO) | HMPV | E. coli |
Inactive precursor that is cleaved to give rise to the mature F1 and F2 fusion glycoproteins.; Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native st... | |||
TMPY-06623 | CB2/CNR2 Protein, Human, Recombinant | Human | HEK293 Cells |
Genetic variants within the CNR2 gene encoding the cannabinoid receptor CB2 are associated with osteoporosis and low bone mineral density (BMD) in case-control studies. There is a possibility that genetic variants of the... | |||
TMPH-00206 | Pertactin autotransporter Protein, Bordetella pertussis, Recombinant (His & SUMO) | Bordetella pertussis | E. coli |
Agglutinogen that binds to eukaryotic cells; a process mediated by the R-G-D sequence. Pertactin may have a role in bacterial adhesion, and thus play a role in virulence. May contribute to the disease state of whooping c... | |||
TMPJ-00464 | APE Protein, Human, Recombinant | Human | E. coli |
Apurinic-Apyrimidinic Endonuclease 1 (APE1) is required for efficient DNA base excision repair. When the DNA glycosylase remove the damaged bases, APE1 cleaves the AP site to allow resynthesis and ligation to complete re... | |||
TMPK-00882 | B7-2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... | |||
TMPH-02509 | ANGPTL8 Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storag... | |||
TMPH-01286 | EEF2 Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly form... | |||
TMPH-01090 | CBX8 Protein, Human, Recombinant (His) | Human | E. coli |
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex... | |||
TMPJ-01377 | Testin Protein, Human, Recombinant (His) | Human | E. coli |
Testin belongs to the prickle/espinas/testin family. Testin contains three LIM zinc-binding domains and one PET domain, TES as a scaffold protein that may have a role in cell adhesion, cell spreading and in the reorganiz... | |||
TMPY-04771 | CARKL Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
CARKL, also known as SHPK, is a nonprotein kinase of glucose metabolism. CARKL has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibi... | |||
TMPJ-00972 | CDKN1B Protein, Human, Recombinant (His) | Human | E. coli |
Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B) is a Kinesin-related motor protein necessary for mitotic spindle assembly and chromosome segregation. CDKN1B is expressed in all tissues with highest levels observed in skele... | |||
TMPH-02175 | TAF5L Protein, Human, Recombinant (GST) | Human | E. coli |
Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex.... | |||
TMPJ-00946 | TALDO1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Transaldolase (TALDO1) belongs to the transaldolase family of Type 1 subfamily. TALDO1 is expressed selectively in oligodendrocytes of the brain. TALDO1 is a key enzyme of the nonoxidative pentose phosphate pathway provi... | |||
TMPY-03059 | Tubulin cofactor A Protein, Human, Recombinant | Human | E. coli |
Tubulin folding cofactor A belongs to the TBCA family. It is one of four proteins (cofactors A, D, E, and C) involved in the early step of the tubulin folding pathway. These proteins can fold intermediates and finally le... | |||
TMPK-00653 | B7-2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... | |||
TMPJ-01192 | ELAPOR1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Endosome/lysosome-associated apoptosis and autophagy regulator (ELAPOR1), also known as EIG121 protein, is a type I transmembrane protein induced by estrogen. The estrogen-induced gene 121 (EIG121) has been associated wi... | |||
TMPH-02510 | ANGPTL8 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storag... | |||
TMPU-00003 | STAT2 Protein, Human, Recombinant (His) | Human | E. coli |
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading... | |||
TMPY-02802 | GNG13 Protein, Human, Recombinant (His) | Human | E. coli |
GNG13 is a subunit of heterotrimeric G proteins which consist of alpha, beta, and gamma subunits. Heterotrimeric G proteins are membrane-bound GTPases that are linked to 7-TM receptors. They function as signal transducer... | |||
TMPY-02135 | S100A16 Protein, Human, Recombinant | Human | E. coli |
S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-hand motifs. S100 proteins are cell- and tissue-specific and are involved in many intra- and extracellular processes through interacting wit... | |||
TMPY-02240 | STAT1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate t... | |||
TMPH-00540 | Epstein-Barr virus (strain GD1) LMP1 Protein (His) | EBV | P. pastoris (Yeast) |
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several s... | |||
TMPJ-00961 | STAT1 Protein, Human, Recombinant | Human | E. coli |
Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer term... | |||
TMPK-00880 | B7-2 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... | |||
TMPK-00881 | B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the acti... | |||
TMPH-03443 | GPX2 Protein, S. cerevisiae, Recombinant (His & Myc) | Saccharomyces cerevisiae | E. coli |
Glutathione peroxidase-like protein that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress. Plays an important role in the oxidative stress-induced response in the pres... | |||
TMPY-00176 | FNDC4 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
FNDC4 acts as an anti-inflammatory factor on macrophages and improves mouse model of induced colitis. FNDC4 could suppress osteoclast formation via NF-kappaB pathway and downregulation of CXCL10. Analysis of binding of F... | |||
TMPJ-01055 | HBA1 Protein, Human, Recombinant (His) | Human | E. coli |
Hemoglobin subunit alpha 1 (HBA1), also known as α2β2, is a hetero-tetramer consisting of two α and two β subunits held together by non-covalent interactions. Each subunit contains a heme group with an iron atom in the F... | |||
TMPJ-00168 | HVEM Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Mouse Protein Tnfrsf14, is a type I transmembrane protein belonging to the TNF receptor superfamily. It is tumor necrosis factor receptor superfamily member 14 and expressed on the surface of T cells during the resting s... | |||
TMPH-00542 | Epstein-Barr virus (strain Raji) LMP1 Protein (His) | EBV | P. pastoris (Yeast) |
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several s... | |||
TMPY-00473 | NRBF2 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
NRBF2 (Nuclear Receptor Binding Factor 2) is a Protein Coding gene. The encoded protein may modulate transcriptional activation by target nuclear receptors. It is widely expressed in the appendix, placenta, and other tis... | |||
TMPH-02585 | ACOD1 Protein, Mouse, Recombinant (His & Myc) | Mouse | Baculovirus Insect Cells |
Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory inna... | |||
TMPH-01551 | IFNLR1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the ... | |||
TMPH-00541 | Epstein-Barr virus (strain AG876) LMP1 Protein (His & Myc) | EBV | E. coli |
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several s... | |||
TMPJ-01473 | BMP-7 Protein, Human, Recombinant | Human | HEK293 Cells |
Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist,... | |||
TMPJ-00884 | CXCL9 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor foun... | |||
TMPY-02582 | Ferritin light chain Protein, Human, Recombinant (His) | Human | E. coli |
Ferritin, light polypeptide (FTL) is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light... | |||
TMPJ-00554 | Vinculin Protein, Human, Recombinant | Human | E. coli |
Vinculin is a focal adhesion and cytoskeletal protein that distributed mainly at cell-cell junctions and cell-extracellular matrix (ECM) adhesion that belongs to the Vinculin/α-Catenin family. Vinculin is an Actin-bindin... | |||
TMPY-00323 | Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST) | HCV | E. coli |
HCV NS3 displays three enzymatic activities: serine protease, NTPase, and RNA helicase. HCV NS3 serine protease, in association with NS4A, is responsible for the cleavages of NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B... | |||
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カタログ番号 | 製品名 | ||
---|---|---|---|
L2195 | Anti-Prostate Cancer Compound Library | 2070 compounds | |
2070 compounds associated with prostate cancer that can be used for high-throughput and high-content screening. | |||
L8300 | Chromatin Modification Compound Library | 250 compounds | |
A unique collection of 250 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS); | |||
L5200 | Anti-Metabolism Disease Compound Library | 1544 compounds | |
A unique collection of 1544 metabolism diseases related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L2910 | Antioxidant Compound Library | 1314 compounds | |
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. ... | |||
L8110 | Reprogramming Compound Library | 1813 compounds | |
A unique collection of 1813 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening. | |||
L2140 | Cancer Cell Differentiation Compound Library | 406 compounds | |
A unique collection of 406 cancer cell differentiation inducing compounds for high throughput and high content screening; | |||
L3800 | NF-κB Signaling Compound Library | 729 compounds | |
A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening; |