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天然化合物

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カタログ番号	製品名	別名	ターゲット
TP1453	Tau protein (592-597), Human TFA		Others
	Tau protein (592-597), Human (TFA) is a peptide fragment of human Tau protein.		Others
T37051	Tau tracer 2
	Tau tracer 2 (Pl-2620) is a specific imaging agent designed to detect and visualize Tau protein aggregates. Its primary application lies in the diagnosis of neurodegenerative diseases [1].
T39660	Tau tracer 1
	Tau tracer 1 is a radiopharmaceutical agent designed specifically for visualizing Tau protein aggregates, commonly associated with neurodegenerative diseases. Its primary application lies in the diagnosis of these condit...
T62899	Tau-aggregation and neuroinflammation-IN-1		Microtubule Associated , NO Synthase
	Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-length tau protein aggregates. Tau-aggregation and neuroinflamma...		Microtubule Associated , NO Synthase
T6405	Bepotastine Besilate	Talion,TAU 284,Bepreve,Bepotastine Beslilate	Histamine Receptor
	Bepotastine Besilate (TAU 284) is a non-sedating and selective H1 receptor antagonist (pIC50: 5.7).		Histamine Receptor
T39781	Aβ/tau aggregation-IN-1
	Aβ/tau aggregation-IN-1 is a potent inhibitor of Aβ 1-42 β-sheet formation and tau aggregation. It exhibits K D values of 160 μM and 337 μM with Aβ 1-42 and tau, respectively. Additionally, Aβ/tau aggregation-IN-1 can pe...
T40409	Tau Peptide (275-305) (Repeat 2 domain)
	Tau Peptide (275-305), also known as the R2 domain fragment, represents the second repeat unit of the microtubule-binding domain of the Alzheimer's tau peptide. Tau Peptide (275-305) is considered crucial in determining ...
TP1420	Microtubule-associated protein tau (26-44)
	Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.
T63481	Tau-aggregation-IN-1
	Tau-aggregation-IN-1 is a dopamine D2 and D3 receptor agonist and an inhibitor of tau441 protein aggregation (IC50: 21 μM).
T74811	tau/Aβ40 aggregation-IN-1
	Tau/Aβ40 aggregation-IN-1 (Compound 20) functions as an inhibitor for tau and Aβ 40 aggregation, exhibiting IC50 values of 1.8 μM and 1.3 μM, respectively [1].
T78173	Aβ/tau aggregation-IN-3
	Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functional aggregation assay. This compound demonstrates anti-amyloid activ...
T79038	Tau protein aggregation-IN-1
	Tau Protein Aggregation-IN-1 (Compound 0c) serves as an inhibitor of Tau protein aggregation, applicable in research related to protein folding disorders including Alzheimer's disease, dementia, Parkinson's disease, Hunt...
T76661	Acetyl-Tau Peptide (273-284) amide
	Acetyl-Tau Peptide (273-284) amide, an acetylated fragment of the Tau peptide, acts as an inhibitor to prevent significant aggregation of Ac-Aβ(25–35)-NH2. Furthermore, it serves as a model for studying the cross-interac...
T81031	tau protein/α-synuclein-IN-1
	Tau protein/α-synuclein-IN-1 is a dual inhibitor that not only impedes tau protein and α-synuclein but also reduces the development of α-syn inclusions in M17D neuroblastoma cells, making it a useful agent in the study o...
T17011	TCH-165		Proteasome
	TCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S levels. The increase in the level of free 20S corresponds to enhanced proteolysis of IDPs.		Proteasome
T22012	7BIO		FLT , DYRK , Aurora Kinase
	7-bromoindirubin-3'-oxime (7BIO) is a caspase independent nonapoptotic cell death inducer. 7BIO is an inhibitor of FLT3, DYRK1A, DYRK2, Aurora B and Aurora C kinases.		FLT , DYRK , Aurora Kinase
T1862	PR-619	PR 619,2,6-Diamino-3,5-dithiocyanopyridine	Apoptosis , DUB , Autophagy
	PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs).		Apoptosis , DUB , Autophagy
T7530	PD146176	NSC168807	Ferroptosis , Lipoxygenase , Autophagy
	PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology...		Ferroptosis , Lipoxygenase , Autophagy
T9611	PF-04802367		GSK-3
	PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay. It shows desirable central nervous system (CNS) properties and ...		GSK-3
T22118	NQTrp		Microtubule Associated
	NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.		Microtubule Associated
T7003	Leucomethylene blue mesylate	TRx0237 mesylate,TRx0237 (LMTX) mesylate,Methylene blue leuco base mesylate salt,Leucomethylene Blue Dimesylate	Beta Amyloid , Microtubule Associated
	Leucomethylene blue mesylate (TRx0237 mesylate) is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia.		Beta Amyloid , Microtubule Associated
T13094	Tauroxicum	Taurox SB	Others
			Others
T64377	AGI-41998 tautomers		Others
	AGI-41998 tautomers is a tautomerism of pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-[(2,2,2-trifluoroethyl)amino]-. pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-...		Others
T6993	Tauroursodeoxycholate sodium	Sodium tauroursodeoxycholate,Tauroursodeoxycholic acid sodium salt,TUDC,Sodium Tauroursodeoxycholate (TUDC)	Apoptosis , ERK , Caspase
	Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.		Apoptosis , ERK , Caspase
T7533	Taurolidine		Apoptosis , Others , Antibacterial , Antibiotic
	Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity.		Apoptosis , Others , Antibacterial , Antibiotic
T3689	Ruboxistaurin hydrochloride	Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride	PKC
	Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCβI and PKCβII (IC50 values are 4.7 and 5.9 nM respectively). Sel...		PKC
T11035	DiABZI STING agonist-1 (Tautomerism)	diABZI STING agonist (Compound 3)	STING
	diABZI STING agonist-1 (Tautomerism) (diABZI STING agonist (Compound 3)) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.		STING
T6280	Enzastaurin	LY317615	Apoptosis , PKC , Autophagy
	Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.		Apoptosis , PKC , Autophagy
T3211	Midostaurin	N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251	Others , PKC
	PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel...		Others , PKC
T9154	Sodium taurodeoxycholate hydrate	Taurodeoxycholic acid sodium salt monohydrate	Others
	Sodium taurodeoxycholate hydrate (Taurodeoxycholic acid sodium salt monohydrate) has been used in a study to assess the effect of submicellar concentrations of bile salts on the lipid bilayer membrane.		Others
T6278	Sotrastaurin	AEB071	PKC
	Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).		PKC
T12036	Midostaurin-D5	PKC412-D5,CGP 41251-D5	Others
	Midostaurin-D5 is a deuterium labeled Midostaurin.		Others
T16998	Tauroursodeoxycholate dihydrate	Taurolite dihydrate,TUDCA dihydrate,UR 906 dihydrate	ERK , Caspase
	Tauroursodeoxycholate dihydrate is an endoplasmic reticulum stress inhibitor. Tauroursodeoxycholate also inhibits ERK. Tauroursodeoxycholate significantly decreases the expression of apoptosis molecules, such as caspase-...		ERK , Caspase
T30003	Ammonium acryloyldimethyltaurate
	Ammonium acryloyldimethyltaurate is a bioactive chemical.
T3689L	Ruboxistaurin mesylate	LY-333531,LY333531,LY 333531,LY-333531 Mesylate
	Ruboxistaurin is a PKC beta inhibitor. Ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Ruboxistaurin attenuates diabetic ne...
T77991	Glutaurine TFA	Litoralon TFA
	Glutaurine (Litoralon) TFA, a compound featuring glutamine and taurine residues, functions as an orally active parathyroid hormone. Originating from the oxyphil cells of the parathyroid gland, this hormone is employed in...
T12280	O-Desmethyl Midostaurin	CGP62221,O-Desmethyl PKC412	Others
	O-Desmethyl Midostaurin is the active Midostaurin metabolite via cytochrome P450 liver enzyme metabolism.		Others
T126442	N-Methyltaurine
	N-Methyltaurine is a useful organic compound for research related to life sciences. The catalog number is T126442 and the CAS number is 107-68-6.
T63793	Tauro-ω-muricholic acid sodium
	Tauro-ω-muricholic acid sodium (TωMCA sodium) is an analogue of tauro-α-muricholic acid, a bile acid of hepatic origin. Tauro-ω-muricholic acid sodium can be used as a serum marker for early onset neonatal sepsis (EOS) a...
T69354	Enzastaurin 2HCl
	Enzastaurin 2HCl (DB-102 2HCl) is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity, which selectively inhibits PKCβ.
T35423	7-oxo Staurosporine
	7-oxo Staurosporine is an antibiotic originally isolated from S. platensis with diverse biological activites. It inhibits PKC, PKA, phosphorylase kinase, EGFR, and c-Src in vitro (IC50s = 9, 26, 5, 200, and 800 nM, respe...
T37771	Taurolithocholic Acid 3-sulfate (sodium salt)
	Taurolithocholic acid 3-sulfate (TLCA3S) is a metabolite of the conjugated bile acid taurolithocholic acid . TLCA3S has been used to study bile acid transport in cellular models and to induce pancreatitis in mouse models...
T13093	Tauro-β-muricholic acid sodium	T-βMCA sodium	FXR
	Tauro-β-muricholic Acid sodium is a endogenous metabolite, is a competitive and reversible antagonist of farnesoid X receptor (FXR)(IC50 of 40 μM).		FXR
T16941	Stauprimide		Others
	Stauprimide is a non-broad spectrum inhibitor that binds to the MYC transcription factor NME2 and blocks its nuclear localization in ESCs, which causes down-regulation of MYC transcription.		Others
T37416	Tauro-α-muricholic Acid (sodium salt)
	Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary bile acid α-muricholic acid . TαMCA is common in rodents but h...
T32602	Laurylsarcosyltaurine	Lauryl-sar-taurine
	Laurylsarcosyltaurine is a surface active constituent of crab gastric juice.
T65644	N-Cyclohexyltaurine
	N-Cyclohexyltaurine is a useful organic compound for research related to life sciences. The catalog number is T65644 and the CAS number is 103-47-9.
T69990	Ruboxistaurin mesylate monohydrate
	Ruboxistaurin mesylate monohydrate is a PKC beta inhibitor potentially for the treatment of diabetic nephropathy and diabetic macular edema. Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/Smad and...
T30270	Azidobenzamidotaurocholate
	Azido Benzamido Taurocholate is a bile acid transporter.
T33878	Pantoyltaurine	NSC 122022,NSC 3086,NSC3086,NSC-3086
	Pantoyltaurine is a biochemical.

Compounds

Tau protein (592-597), Human TFA

Tau-aggregation and neuroinflammation-IN-1

T62899

Synonym:

Target: Microtubule Associated, NO Synthase

Bepotastine Besilate

T6405

Synonym: Talion,TAU 284,Bepreve,Bepotastine Beslilate

Target: Histamine Receptor

Aβ/tau aggregation-IN-1

T39781

Synonym:

Target:

Tau Peptide (275-305) (Repeat 2 domain)

T40409

Synonym:

Target:

Microtubule-associated protein tau (26-44)

TP1420

Synonym:

Target:

Tau-aggregation-IN-1

T63481

Synonym:

Target:

tau/Aβ40 aggregation-IN-1

T74811

Synonym:

Target:

Aβ/tau aggregation-IN-3

T78173

Synonym:

Target:

Tau protein aggregation-IN-1

T79038

Synonym:

Target:

Acetyl-Tau Peptide (273-284) amide

T76661

Synonym:

Target:

tau protein/α-synuclein-IN-1

Target: FLT, DYRK, Aurora Kinase

PR-619

T1862

Synonym: PR 619,2,6-Diamino-3,5-dithiocyanopyridine

Target: Apoptosis, DUB, Autophagy

PD146176

T7530

Synonym: NSC168807

Target: Ferroptosis, Lipoxygenase, Autophagy

Target: Microtubule Associated

Leucomethylene blue mesylate

T7003

Synonym: TRx0237 mesylate,TRx0237 (LMTX) mesylate,Methylene blue leuco base mesylate salt,Leucomethylene Blue Dimesylate

Target: Beta Amyloid, Microtubule Associated

AGI-41998 tautomers

T64377

Synonym:

Target: Others

Tauroursodeoxycholate sodium

T6993

Synonym: Sodium tauroursodeoxycholate,Tauroursodeoxycholic acid sodium salt,TUDC,Sodium Tauroursodeoxycholate (TUDC)

Target: Apoptosis, ERK, Caspase

Taurolidine

T7533

Synonym:

Target: Apoptosis, Others, Antibacterial, Antibiotic

Ruboxistaurin hydrochloride

T3689

Synonym: Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride

Target: PKC

diABZI STING agonist-1 (Tautomerism)

T11035

Synonym: diABZI STING agonist (Compound 3)

Target: Apoptosis, PKC, Autophagy

Midostaurin

T3211

Synonym: N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251

Target: Others, PKC

Sodium taurodeoxycholate hydrate

T9154

Synonym: Taurodeoxycholic acid sodium salt monohydrate

Synonym: PKC412-D5,CGP 41251-D5

Target: Others

Tauroursodeoxycholate dihydrate

T16998

Synonym: Taurolite dihydrate,TUDCA dihydrate,UR 906 dihydrate

Target: ERK, Caspase

Ammonium acryloyldimethyltaurate

T30003

Synonym:

Target:

Ruboxistaurin mesylate

T3689L

Synonym: LY-333531,LY333531,LY 333531,LY-333531 Mesylate

Target:

Glutaurine TFA

T77991

Synonym: Litoralon TFA

Target:

O-Desmethyl Midostaurin

T12280

Synonym: CGP62221,O-Desmethyl PKC412

Tauro-ω-muricholic acid sodium

Taurolithocholic Acid 3-sulfate (sodium salt)

T37771

Synonym:

Target:

Tauro-β-muricholic acid sodium

T13093

Synonym: T-βMCA sodium

Tauro-α-muricholic Acid (sodium salt)

T37416

Synonym:

Target:

Laurylsarcosyltaurine

T32602

Synonym: Lauryl-sar-taurine

Ruboxistaurin mesylate monohydrate

T69990

Synonym:

Target:

Azidobenzamidotaurocholate

Synonym: NSC 122022,NSC 3086,NSC3086,NSC-3086

Target:

カタログ番号	製品名	別名	ターゲット
T14046	Anandamide	(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide	Cannabinoid Receptor , Endogenous Metabolite
	Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) in the central nervous sy...		Cannabinoid Receptor , Endogenous Metabolite
T4727	Taurolithocholic acid sodium salt	Sodium taurolithocholate	Others , Calcium Channel
	Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but not to M2 or M3 receptors.		Others , Calcium Channel
TN2259	Taurocholic acid	N-Choloyltaurine	TNF , PI3K
	Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.Taurocholic acid is cytoprotective, preventing tumor necrosis factor-alpha-induced cholangiocyte damage via a PI3K-mediated pathwa...		TNF , PI3K
T2A2481	Taurochenodeoxycholic Acid	Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine	Apoptosis , TNF , Caspase , Endogenous Metabolite
	Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.		Apoptosis , TNF , Caspase , Endogenous Metabolite
TWA2417	Sodium taurocholate	Taurocholate Sodium	Others
	Sodium taurocholate (Taurocholate Sodium) hydrate is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and...		Others
T8092	Taurohyodeoxycholic acid sodium salt	Sodium taurohyodeoxycholate hydrate	Caspase
	Taurohyodeoxycholic acid sodium salt (Sodium taurohyodeoxycholate hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation.		Caspase
T13092	Tauro-Obeticholic acid		FXR
	Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).		FXR
T2532	Tauroursodeoxycholate	Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA	Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
	Tauroursodeoxycholate (UR 906), also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. Tauroursodeoxycholate is the more hydrophilic form of ursode...		Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
T6680	Staurosporine	Antibiotic AM-2282,AM-2282,CGP 41251	Apoptosis , PKA , Antibacterial , Antibiotic , Src , PKC , Antifungal
	Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces...
T1138	Taurocholic acid sodium salt hydrate	Sodium taurocholate hydrate,Taurocholic Acid sodium hydrate	Others , Potassium Channel , Endogenous Metabolite
	Taurocholic acid sodium salt hydrate (Sodium taurocholate hydrate) is the product of conjugation of taurine with cholic acid. The sodium salt, the main ingredient of the bile of carnivorous animals, is used as a detergen...		Others , Potassium Channel , Endogenous Metabolite
TN2349	Taurodeoxycholate sodium salt	Sodium taurodeoxylate	Endogenous Metabolite
	Taurodeoxycholate sodium salt (Sodium taurodeoxylate) is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. and it inhibits various inflammatory...		Endogenous Metabolite
T5225	Hypotaurine	2-Aminoethanesulfinic acid,2-Aminoethylsulfinic acid	Chloride channel , Endogenous Metabolite
	Hypotaurine (2-Aminoethanesulfinic acid), functioning as an intermediate in the biosynthesis of taurine from cysteine within astrocytes, acts as an endogenous inhibitory amino acid targeting the glycine receptor.		Chloride channel , Endogenous Metabolite
TJA2398	Taurodeoxycholic acid sodium hydrate	Sodium taurodeoxycholate monohydrate,Taurodeoxychloic Acid sodium hydrate,Taurohyodeoxycholic acid sodium salt	Apoptosis , Caspase
	Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.		Apoptosis , Caspase
TN2215	Taurochenodeoxycholic acid sodium	Sodium taurochenodeoxycholate	Apoptosis , Endogenous Metabolite
	Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and...		Apoptosis , Endogenous Metabolite
T75319	Taurodeoxycholic acid	Taurodeoxychloic acid	Apoptosis , Calcium Channel , Caspase
	Taurodeoxycholic acid (Taurodeoxychloic acid) is a bile acid taurine conjugate of deoxycholic acid, a human metabolite that stabilizes mitochondrial membranes and reduces the formation of free radicals.Taurodeoxycholic a...		Apoptosis , Calcium Channel , Caspase
T0022	Taurine	2-Aminoethanesulfonic acid	LDL , Endogenous Metabolite , Autophagy
	Taurine (2-Aminoethanesulfonic acid), an organic acid, is distributed in various animal tissues.		LDL , Endogenous Metabolite , Autophagy
T32887	Lotaustralin
	Lotaustralin is a cyanogenic glycoside.
T81097	Stauntoside M
	Stauntoside M, a steroidal glycoside, is isolated from the roots of Cynanchum stauntonii [1].
TN3837	Desmethoxycentaureidin		Others
	Desmethoxycentaureidin shows high inhibitory activity against HeLa cell growth (GI50 9 microM).		Others
T23421	Tautomycetin		Others
	protein phosphatase (PP)1 inhibitor		Others
T81030	Tauro-β-muricholic acid	TβMCA	FXR
	Tauro-β-muricholic acid (TβMCA), a trihydroxylated bile acid, acts as a competitive and reversible FXR antagonist (IC 50 = 40 μM) and exhibits antiapoptotic effects by inhibiting bile acid-induced hepatocellular apoptosi...		FXR
TN5060	Stauntosaponin A		ATPase , Potassium Channel , Sodium Channel
	Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively.		ATPase , Potassium Channel , Sodium Channel
T37770	Taurohyodeoxycholic acid
	Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid .1THDCA decreases the size and weight of human gallstonesin vitro. It increases bile flow, biliary cholesterol ...
TN4009	Erythrocentauric acid		Others
	Erythrocentauric acid is a natural product from Gentiana macrophylla.		Others
TN1233	Lotaustralin	(2RS)-Lotaustralin	Others
	(2RS)-Lotaustralin is a natural product from Rhodiola rosea L.		Others
TN5276	(Z)-Aldosecologanin (Centauroside)		Others
	(Z)-Aldosecologanin is a natural product from Lonicera japonica.		Others
TN4010	Erythrocentaurin		Antifection
	Erythrocentaurin has antibacterial activity; it also exhibits a concentration-dependent α-amylase inhibition (IC(50) 1.67 ± 0.28 mg/mL).		Antifection
T13916	Taurochenodeoxycholate-3-sulfate		Others
	Taurochenodeoxycholate-3-sulfate is a bile salt found in urine.		Others
T4940	3-Methylhistamine dihydrochloride		Others , Endogenous Metabolite
	N tau-methylhistamine is one of the histamine metabolites. N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determination of this histamine metabolite is generally less hampere...		Others , Endogenous Metabolite
T3914	Saikosaponin C		Beta Amyloid , Caspase
	Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.		Beta Amyloid , Caspase
T32614	L-Clausenamide	(-)-Clausenamide	Microtubule Associated
	L-Clausenamide is an alkaloid extracted from the leaves of the yellow bark (Clausena lansium (Lour) skeels) and can be used to improve cognitive function. L-Clausenamide inhibits beta-amyloid (Aβ) toxicity and prevents t...		Microtubule Associated
T27977	Manzamine A	Keramamine A
	Manzamine A is a GSK-3 inhibitor and vacuolar ATPase uncoupler found in marine sponges. It inhibits autophagy and tumor growth in cancer models, suppresses foam cell formation in macrophages, prevents growth of gram nega...

天然物製品

Anandamide

T14046

Synonym: (5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide

Target: Cannabinoid Receptor, Endogenous Metabolite

Taurolithocholic acid sodium salt

T4727

Synonym: Sodium taurolithocholate

Target: Others, Calcium Channel

Taurocholic acid

TN2259

Synonym: N-Choloyltaurine

Target: TNF, PI3K

Taurochenodeoxycholic Acid

T2A2481

Synonym: Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine

Target: Apoptosis, TNF, Caspase, Endogenous Metabolite

Sodium taurocholate

TWA2417

Synonym: Taurocholate Sodium

Target: Others

Taurohyodeoxycholic acid sodium salt

T8092

Synonym: Sodium taurohyodeoxycholate hydrate

Target: Caspase

Tauro-Obeticholic acid

T13092

Synonym:

Target: FXR

Tauroursodeoxycholate

T2532

Synonym: Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA

Target: Apoptosis, ERK, P450, Caspase, Endogenous Metabolite

Staurosporine

T6680

Synonym: Antibiotic AM-2282,AM-2282,CGP 41251

Target: Apoptosis, PKA, Antibacterial, Antibiotic, Src, PKC, Antifungal

Taurocholic acid sodium salt hydrate

T1138

Synonym: Sodium taurocholate hydrate,Taurocholic Acid sodium hydrate

Target: Others, Potassium Channel, Endogenous Metabolite

Taurodeoxycholate sodium salt

TN2349

Synonym: Sodium taurodeoxylate

Target: Endogenous Metabolite

Hypotaurine

T5225

Synonym: 2-Aminoethanesulfinic acid,2-Aminoethylsulfinic acid

Target: Chloride channel, Endogenous Metabolite

Taurodeoxycholic acid sodium hydrate

TJA2398

Synonym: Sodium taurodeoxycholate monohydrate,Taurodeoxychloic Acid sodium hydrate,Taurohyodeoxycholic acid sodium salt

Target: Apoptosis, Caspase

Taurochenodeoxycholic acid sodium

TN2215

Synonym: Sodium taurochenodeoxycholate

Target: Apoptosis, Endogenous Metabolite

Taurodeoxycholic acid

T75319

Synonym: Taurodeoxychloic acid

Target: Apoptosis, Calcium Channel, Caspase

Taurine

T0022

Synonym: 2-Aminoethanesulfonic acid

Target: LDL, Endogenous Metabolite, Autophagy

Desmethoxycentaureidin

Tauro-β-muricholic acid

Target: ATPase, Potassium Channel, Sodium Channel

Taurohyodeoxycholic acid

T37770

Synonym:

Target:

Erythrocentauric acid

Synonym: (2RS)-Lotaustralin

Target: Others

(Z)-Aldosecologanin (Centauroside)

Taurochenodeoxycholate-3-sulfate

T13916

Synonym:

Target: Others

3-Methylhistamine dihydrochloride

T4940

Synonym:

Target: Others, Endogenous Metabolite

Saikosaponin C

T3914

Synonym:

Target: Beta Amyloid, Caspase

L-Clausenamide

T32614

Synonym: (-)-Clausenamide

Target: Microtubule Associated

Manzamine A

T27977

Synonym: Keramamine A

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-03425	Tau Protein, Human, Recombinant (His)	Human	E. coli
	MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are...
TMPJ-00827	Tau-D Protein, Human, Recombinant (His)	Human	E. coli
	Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. ...
TMPJ-00828	Tau-F Protein, Human, Recombinant	Human	E. coli
	Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons...
TMPH-03336	Tau Protein, Rat, Recombinant (His)	Rat	HEK293
	Tau Protein, Rat, Recombinant (His) is expressed in HEK293.
TMPH-02785	Tau Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Tau Protein, Mouse, Recombinant (His) is expressed in HEK293.
TMPH-01683	Tau Protein, Human, Recombinant (HEK293, His)	Human	HEK293
	Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane com...
TMPH-02444	Tau Protein, Rhesus macaque, Recombinant (His)	Rhesus	HEK293
	Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane com...
TMPH-03335	Tau Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	Tau Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli.
TMPH-02443	Tau Protein, Rhesus macaque, Recombinant (His & SUMO)	Rhesus	E. coli
	Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane com...
TMPH-00279	Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (His)	Bovine	Yeast
	Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-...
TMPH-00278	Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (E. coli, His)	Bovine	E. coli
	Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-...
TMPH-01171	CDK5 Protein, Human, Recombinant	Human	E. coli
	CDK5 Protein, Human, Recombinant is expressed in E. coli.
TMPY-00007	Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant	Mouse	Yeast
	IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interfero...
TMPY-00265	Interferon alpha 2/IFNA2 Protein, Human, Recombinant	Human	Yeast
	IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interfero...
TMPY-01085	VLDLR Protein, Human, Recombinant (His)	Human	HEK293
	The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and A...
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPY-01715	CDC37 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is...
TMPY-03534	CDC37 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is...
TMPY-03558	CDC37 Protein, Mouse, Recombinant	Mouse	Baculovirus-Insect Cells
	CDC37 is a protein that is expressed in proliferative zones during embryonic development and in adult tissues, consistent with a positive role in proliferation and is required for cell division in budding yeast. CDC37 is...
TMPY-02378	14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST)	Human	E. coli
	The recently identified 14-3-3 tau, whose corresponding gene name is YWHAQ, is in a hypoxia-treated human trophoblast cell line. YWHAQ may play a role in epigenetic regulation of placental genes in the onset of Preeclamp...
TMPJ-01076	FKBP4 Protein, Human, Recombinant (His)	Human	E. coli
	FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone recepto...
TMPK-01146	LGMN Protein, Human, Recombinant (His)	Human	HEK293
	Recently, functional studies have demonstrated that legumain (LGMN) cleaves both amyloid β-protein precursor and tau, promoting senile plaques and formation of neurofibrillary tangles, which may play a crucial role in th...
TMPH-02229	TRA2B Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor ne...
TMPH-01900	DDX5 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop r...
TMPH-02228	TRA2B Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor ne...
TMPH-02180	TTBK2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Serine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother cent...
TMPY-04556	CDK5 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Cell division protein kinase 5, also known as Cyclin-dependent kinase 5, Serine/threonine-protein kinase PSSALRE, Tau protein kinase II catalytic subunit, TPKII catalytic subunit and CDK5, is a cytoplasm protein which...
TMPY-02340	HNMT Protein, Human, Recombinant (GST)	Human	E. coli
	HNMT (Histamine N-methyltransferase) is a Protein Coding gene. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. HNMT, the major enzyme for the metabol...
TMPY-00096	Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant	Rhesus	Yeast
	IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interfero...
TMPY-06407	Interferon alpha 2/IFNA2 Protein, Human, Recombinant (hFc)	Human	HEK293
	IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interfero...
TMPY-02661	Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interfero...
TMPY-03735	Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interfero...
TMPY-03319	Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (mFc)	Rhesus	HEK293
	IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interfero...
TMPH-02479	PRKAA1 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activat...
TMPH-02478	PRKAA1 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus
	Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activat...
TMPH-00308	ISG15 Protein, Bovine, Recombinant (His)	Bovine	E. coli
	Ubiquitin-like protein which plays a key role in the innate immune response to viral infection either via its conjugation to a target protein (ISGylation) or via its action as a free or unconjugated protein. ISGylation i...
TMPY-00808	FKBP12 Protein, Human, Recombinant (His)	Human	E. coli
	FK506 binding protein 12 (FKBP12), also known as FKBP1, along with cyclophilin, are two major members of the immunophilin protein family who serve as receptors for the immunosuppressant drugs cyclosporin A and FK506. As ...
TMPY-01662	FKBP12 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	FK506 binding protein 12 (FKBP12), also known as FKBP1, along with cyclophilin, are two major members of the immunophilin protein family who serve as receptors for the immunosuppressant drugs cyclosporin A and FK506. As ...
TMPH-00009	OGT Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc...

Tau Protein, Human, Recombinant (His)

TMPY-03425

Species: Human

Expression System: E. coli

Tau-D Protein, Human, Recombinant (His)

TMPJ-00827

Species: Human

Expression System: E. coli

Tau-F Protein, Human, Recombinant

TMPJ-00828

Species: Human

Expression System: E. coli

Tau Protein, Rat, Recombinant (His)

TMPH-03336

Species: Rat

Expression System: HEK293

Tau Protein, Mouse, Recombinant (His)

TMPH-02785

Species: Mouse

Expression System: HEK293

Tau Protein, Human, Recombinant (HEK293, His)

TMPH-01683

Species: Human

Expression System: HEK293

Tau Protein, Rhesus macaque, Recombinant (His)

TMPH-02444

Species: Rhesus

Expression System: HEK293

Tau Protein, Rat, Recombinant (E. coli, His)

TMPH-03335

Species: Rat

Expression System: E. coli

Tau Protein, Rhesus macaque, Recombinant (His & SUMO)

TMPH-02443

Species: Rhesus

Expression System: E. coli

Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (His)

TMPH-00279

Species: Bovine

Expression System: Yeast

Interferon tau-1/IFNT1 Protein, Bovine, Recombinant (E. coli, His)

TMPH-00278

Species: Bovine

Expression System: E. coli

CDK5 Protein, Human, Recombinant

TMPH-01171

Species: Human

Expression System: E. coli

Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant

TMPY-00007

Species: Mouse

Expression System: Yeast

Interferon alpha 2/IFNA2 Protein, Human, Recombinant

TMPY-00265

Species: Human

Expression System: Yeast

VLDLR Protein, Human, Recombinant (His)

TMPY-01085

Species: Human

Expression System: HEK293

C-ABL/ABL1 Protein, Human, Recombinant (GST)

TMPY-04396

Species: Human

Expression System: Baculovirus-Insect Cells

CDC37 Protein, Human, Recombinant (GST)

TMPY-01715

Species: Human

Expression System: Baculovirus-Insect Cells

CDC37 Protein, Mouse, Recombinant (His & GST)

TMPY-03534

Species: Mouse

Expression System: Baculovirus-Insect Cells

CDC37 Protein, Mouse, Recombinant

TMPY-03558

Species: Mouse

Expression System: Baculovirus-Insect Cells

14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST)

TMPY-02378

Species: Human

Expression System: E. coli

FKBP4 Protein, Human, Recombinant (His)

TMPJ-01076

Species: Human

Expression System: E. coli

LGMN Protein, Human, Recombinant (His)

TMPK-01146

Species: Human

Expression System: HEK293

TRA2B Protein, Human, Recombinant (His & SUMO)

TMPH-02229

Species: Human

Expression System: E. coli

DDX5 Protein, Human, Recombinant (His & Myc)

TMPH-01900

Species: Human

Expression System: E. coli

TRA2B Protein, Human, Recombinant (His & Myc)

TMPH-02228

Species: Human

Expression System: Baculovirus

TTBK2 Protein, Human, Recombinant (His & Myc)

TMPH-02180

Species: Human

Expression System: E. coli

CDK5 Protein, Human, Recombinant (GST)

TMPY-04556

Species: Human

Expression System: Baculovirus-Insect Cells

HNMT Protein, Human, Recombinant (GST)

TMPY-02340

Species: Human

Expression System: E. coli

Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant

TMPY-00096

Species: Rhesus

Expression System: Yeast

Interferon alpha 2/IFNA2 Protein, Human, Recombinant (hFc)

TMPY-06407

Species: Human

Expression System: HEK293

Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant (hFc)

TMPY-02661

Species: Mouse

Expression System: HEK293

Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (His)

TMPY-03735

Species: Rhesus

Expression System: HEK293

Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (mFc)

TMPY-03319

Species: Rhesus

Expression System: HEK293

PRKAA1 Protein, Mouse, Recombinant (E. coli, His)

TMPH-02479

Species: Mouse

Expression System: E. coli

PRKAA1 Protein, Mouse, Recombinant (His)

TMPH-02478

Species: Mouse

Expression System: Baculovirus

ISG15 Protein, Bovine, Recombinant (His)

TMPH-00308

Species: Bovine

Expression System: E. coli

FKBP12 Protein, Human, Recombinant (His)

TMPY-00808

Species: Human

Expression System: E. coli

FKBP12 Protein, Mouse, Recombinant (His)

TMPY-01662

Species: Mouse

Expression System: E. coli

OGT Protein, Human, Recombinant (His & SUMO)

TMPH-00009

Species: Human

Expression System: E. coli

カタログ番号	製品名
L9840	Anti-Alzheimer's Disease Compound Library	1040 compounds
	A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.
L1310	Cytoskeletal Signaling Pathway Compound Library	773 compounds
	A unique collection of 773 cytoskeleton-related compounds, can be used for HTS and HCS；

ライブラリー

Anti-Alzheimer's Disease Compound Library

L9840

Compounds: 1040

Cytoskeletal Signaling Pathway Compound Library

L1310

Compounds: 773