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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T21632 | Myoseverin | Others , Microtubule Associated | |
Myoseverin, an inducer of the reversible fission of multinucleated myotubes into mononucleated fragments, affecting the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and str... | |||
T8575 | ENFENAMIC ACID | Platelet aggregation | |
Enfenamic acid is a platelet aggregation inhibitor and with antirheumatic. | |||
T16850 | SB-265610 | GSK-CXCR2 | CXCR |
SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and... | |||
T21653 | 1,4-DPCA | HIF/HIF Prolyl-Hydroxylase | |
1,4-DPCA is an inhibitor of prolyl-hydroxylase with an IC50 of 2.4 µM for collagen hydroxylation in human foreskin fibroblasts and 60 μM for factor inhibiting HIF (FIH). | |||
T4478 | CID 16020046 | C390-0219 | Cannabinoid Receptor |
CID 16020046 (C390-0219) is a selective GPR55 antagonist, inhibiting GPR55 constitutive activity with IC50 of 0.15 μM in yeast. | |||
T2206 | Quadrol | N,N,N′,N′-Tetrakis(2-hydroxypropyl)ethylenediamine,EDTP,Edetol | Others |
Quadrol (EDTP) is an immunostimulant, accelerated wound healing. | |||
T19841 | Tribenoside | Glyvenol,Glyvenal,Ba 2140,BG-356,Glivenol,TBGF | Others |
Tribenoside (BG-356) is a vasoprotectant with mild anti-inflammatory, analgesic, and wound healing properties. | |||
T13823 | Polyvinylpyrrolidone | PVP,Povidone,Polyvidone | Others |
Polyvinylpyrrolidone (Polyvidone) used in human and veterinary medicine as an effective wound healing accelerator. | |||
T40570L | LKKTETQ acetate | LKKTETQ acetate (476014-70-7 Free base) | Others |
LKKTETQ acetate is the active site in the protein thymosin β4 responsible for wound healing, actin binding and cell migration. | |||
T0979 | Dequalinium chloride | Dequafungan,Danical,Decabis | Potassium Channel , PKC |
Dequalinium chloride (Decabis) , a topical bacteriostat, is a selective blocker of apamin-sensitive K+ channels. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ... | |||
T22408 | Proflavine | 3,6-Diaminoacridine | Antibacterial |
Proflavine (3,6-Diaminoacridine) (3,6-Diaminoacridine) is a disinfectant bacteriostatic against many gram-positive bacteria and is a topical antiseptic used mainly in wound dressings. | |||
T41206 | Poly Vinyl Alcohol | Polyvinyl alcohol | Others |
Poly Vinyl Alcohol (Polyvinyl alcohol) is a water-soluble, biodegradable, wound-healing polymer used in a wide range of biomedical applications.Poly Vinyl Alcohol is commonly used in the manufacture of medical excipients... | |||
T7116 | Sodium gualenate | Guaiazulenesulfonate sodium | Others |
Sodium gualenate (Guaiazulenesulfonate sodium) (Guaiazulenesulfonate sodium), a hydrophilic derivative of guaiazulene (GA), is an unstable compound. It has anti-inflammatory and wound-healing effects. | |||
TP2319 | Thymosin β4 acetate(75591-33-4 free base) | Autophagy | |
Thymosin β4 (Tβ4) is a thymic hormone with multiple and different intracellular and extracellular activities affecting wound healing, inflammation, fibrosis and tissue regeneration. | |||
T74048 | PAPA NONOate | Endogenous Metabolite , NO Synthase | |
PAPA NONOate is a pH-regulated NO donor.PAPA NONOate has potential antitumor activity and can be used to study diabetic wound healing disorders. | |||
T21550 | Blebbistatin | (±)-Blebbistatin | ATPase , Myosin |
Blebbistatin ((±)-Blebbistatin) is a selective non-muscle myosin II (NMII) inhibitor. It promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing. Furthermore it preserves cell jun... | |||
T77617 | MMP-9-IN-6 | MMP | |
MMP-9-IN-6 is an MMP-9 inhibitor with an IC50 value of 50 μM and good anti-ulcer efficacy.MMP-9-IN-6 has potential anti-tumor activity and can be used to study tissue remodeling, wound repair and atherosclerosis. | |||
T32613 | LCB 03-0110 dihydrochloride | Src | |
LCB 03-0110 Dihydrochloride is a potent inhibitor of the c-Src kinase (IC50 = 1.3 nM) and tyrosine kinases in the BTK and SYK family, as well as in the DDR2 family. It inhibits LPS-induced activation of macrophages and T... | |||
T4425 | JK-P3 | VEGFR | |
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube format... | |||
T4306 | CCG-203971 | CCG203971 | Rho , Ras |
CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This compound also inhibits PC-3 cell migration (IC50: 4.2 μM),... | |||
T41231 | GP 1a | Cannabinoid Receptor , PERK , Arrestin | |
GP 1a is a potent agonist of cannabinoid receptor 2 (CB2) (EC50=7.1), as shown in cAMP, GTPγS and β-arrestin recruitment assays. GP 1a is approximately 30-fold more selective for CB2 receptors than CB1 receptors and incr... | |||
T3616 | Carbazochrome | AC-17,Adrenostazin,Cromadrenal,Adona,Adchnon,Adedolon | Others , Phospholipase |
Carbazochrome (Adchnon) is an antihemorrhagic, or hemostatic, agent that will cease blood flow by causing the aggregation and adhesion of platelets in the blood to form a platelet plug, ceasing blood flow from an open wo... | |||
T28146 | ND-336 | ND336,ND-336 hydrochloride,ND 336 | |
ND-336 is a highly selective inhibitor ofMMP-2, MMP-9 and MMP-14. ND-336 accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound. | |||
T29547 | Acemannan | Acemannanan | |
Acemannan can produce cell proliferation and skin wound healing through AKT/mTOR signaling pathway. | |||
T34693 | Sphingosine phosphorylcholine | ||
Sphingosine phosphorylcholine is a wound healing agent. | |||
T25309 | Dermabond | Liquid Bandage,2-Octyl 2-cyanoacrylate,RiteLok CON 895 | |
Dermabond is an antibacterial compound that has been used in basic science research for wound healing. | |||
T70826 | PF-03671148 | ||
PF-03671148 is a potent ALK inhibitor. PF-03671148 inhibits the expression of fibrotic genes and protein markers both in vitro in human fibroblasts and in vivo in a rat wound repair model. Wound healing is not inhibited ... | |||
T20937 | Dodecenylsuccinic anhydride | Rikacid DDSA,Dodecenylsuccinic acid anhydride,DDSA | Others |
Dodecenylsuccinic anhydride (DDSA) can be grafted with collagen hydrogels as a hydrophobic wound dressing to incorporate simvastatin, which has potential application in the treatment of ulcers and prevention of wound inf... | |||
T30107 | Apratyramide | ||
Apratyramide is a marine-derived peptidic stimulator of VEGF-A and other growth factors with potential application in wound healing. | |||
T40570 | LKKTETQ | ||
LKKTETQ, a peptide segment within thymosin β 4, constitutes the protein's active site responsible for actin binding, cell migration, and wound healing. | |||
T26958 | CAY10583 | CAY 10583,CAY-10583 | |
CAY10583 is an agonist of leukotriene B4 receptor type 2 (BLT2). CAY10583 directly promotes keratinocyte migration and indirectly enhances fibroblast proliferation by increasing keratinocyte production of bFGF1 and TGF-β... | |||
T81330 | Q-Peptide | ||
Q-Peptide, an angiopoietin-1 derived peptide (QHREDGS), enhances keratinocyte migration, thereby facilitating wound healing in a diabetic mouse model, and accelerates wound closure [1]. | |||
T21185 | CEP03 | CEP 03,CEP-03 | |
CEP03 enhances EC/EPC proliferation, tubelike formation, and wound-healing efficiency, leading to promote angiogenesis and significantly improve blood flow perfusion recovery in the ischemic hind limbs of mice. | |||
T34653 | SK1071 | ||
SK1071 is a novel migrastatin analogs, which demonstrated improved performance over migrastatin, with nanomolar IC50 values in chamber cell migration assays with tumor cells and human umbilical vein endothelial cells (HU... | |||
T14139 | Aganepag | AGN 210937 | Prostaglandin Receptor |
Aganepag, a potent Prostanoid EP2 receptor agonist, exhibits remarkable selectivity with an EC50 of 0.19 nM, demonstrating no activity at the EP4 receptor. Its applications are primarily in the fields of wound healing, s... | |||
T82358 | G-{d-Arg}-GDSPASSK | ||
G-{d-Arg}-GDSPASSK is a polypeptide that inhibits cell adhesion, facilitates wound healing, and promotes tissue repair [1]. | |||
T61106 | GRP78-IN-1 | ||
GRP78-IN-1 displays interactions with specific residues on the GRP78 protein with a binding energy of -8.07 kcal/mol. This compound possesses potent cytotoxic and anti-proliferative effects on cancer cells, particularly ... | |||
T41189 | AY 254 | ||
AY 254 is a potent PAR2 biased agonist. Selectively activates ERK1/2 signaling (EC50= 2 nM for ERK1/2 phosphorylation versus 80 nM for Ca2+release). Reduces cytoKi ne-induced caspase 3/8 activation, promotes scratch-woun... | |||
T81404 | Prezatide copper | Bisprezatide copper,PC 1020,Iamin | |
Prezatide copper (also known as Bisprezatide copper or Iamin) serves as an inhibitor of hair loss and is recognized for its multiple wound-healing properties as a human growth factor [1]. | |||
T76235 | Peceleganan | ||
Peceleganan (PL-5), a synthetic hybrid peptide, combines cecropin A (1-10) and melittin B (3-18) sequences to form a (10+16)-peptide analogue with antimicrobial properties. This compound effectively inhibits wound infect... | |||
T74392 | Antimicrobial photosensitizer-1 | ||
Antimicrobial Photosensitizer-1 demonstrates significant potential as an effective agent for treating infections caused by pathogenic microorganisms, with notable antimicrobial efficacy observed in S. aureus-infected mou... | |||
TMIH-0183 | Dequalinium Chloride-d4 | ||
Dequalinium Chloride-d4 is a deuterated compound of Dequalinium Chloride. Dequalinium Chloride has a CAS number of 522-51-0. Dequalinium Chloride, a topical bacteriostat, is a selective blocker of apamin-sensitive K+ cha... | |||
T76235L | Peceleganan acetate | ||
Peceleganan acetate (PL-5), a synthetic hybrid analogue combining segments of cecropin A (1-10) and melittin B (3-18) to form a (10+16)-peptide, demonstrates antimicrobial properties. It is specifically effective in inhi... | |||
T75857 | LL-37, human TFA | ||
LL-37, human TFA, is a cathelicidin-derived, 37-residue, amphipathic antimicrobial peptide that displays a broad spectrum of antimicrobial activity. It may protect the cornea from infection and modulate wound healing [1]... | |||
T75858 | LL-37, human acetate | ||
LL-37, human acetate, is a 37-residue amphipathic peptide derived from cathelicidin, known for its broad-spectrum antimicrobial properties. This compound not only plays a crucial role in safeguarding the cornea against i... | |||
T36080 | Rivenprost | ONO-4819 | |
Prostaglandin E2 activates four distinct G protein-coupled receptors, EP1-4. Rivenprost is a potent and selective agonist for the EP4 receptor (Ki = 0.7, 56, 620, and >10,000 nM for EP4, EP3, EP2, and EP1, respectively).... | |||
T35671 | Salazinic Acid | ||
Salazinic acid is a depsidone lichen metabolite that has been found in P. sulcata.1 It is active against B. cereus, B. subtilis, S. aureus, P. aeruginosa, S. typhimurium, C. albicans, and A. niger in vitro (MICs = 3.9-30... | |||
T35408 | (±)10(11)-EDP Ethanolamide | ||
(±)10(11)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 0.43 and 22.5 nM for CB1 and CB2 receptors, respectively). It is produced though direct epoxygenation of docosah... | |||
T74212 | BLT2 probe 1 | Leukotriene Receptor | |
BLT2 Probe 1 (Compound 13), a fluorescent probe derived from the synthetic BLT2 agonist CAY10583, offers a robust tool for exploring BLT2 receptor ligand pharmacology across various assay systems [1]. As BLT2 is a valuab... | |||
T80859 | Vitronectin | ||
Vitronectin, a multifunctional glycoprotein found in blood and the extracellular matrix, interacts with glycosaminoglycans, collagen, plasminogen, and the urokinase-receptor, in addition to stabilizing the inhibitory con... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T3855 | Tracheloside | Estrogen Receptor/ERR , Phosphorylase | |
Tracheloside significantly decreases the activity of alkaline phosphatase (IC50: 0.31 μg/ml), a level of inhibition comparable to that of tamoxifen (IC50: 0.43 μg/ml). | |||
T3881 | Vaccarin | Integrin , Akt , PERK , AMPK | |
Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, glycosylation and deglycosylation. | |||
T5S1982 | Periplocin | Periplocoside | Apoptosis , Others |
1. Periplocin (Periplocoside) has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. Periplocin is used for treatment of rheumato... | |||
TN1686 | Ginsenoside Rg4 | Antibacterial | |
Ginsenoside Rg4 is a natural product | |||
T4454 | Traumatic Acid | Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,Trans-2-Dodecenedioic Acid | Antioxidant |
Traumatic Acid (Dodec-2-Enedioic Acid) is a product of the hydroperoxide lyase pathway in plants. Potential as a wound healing agent that stimulates cell division near a wound site to form a protective callus. | |||
T2827 | Asiatic acid | Asiantic acid,Dammarolic acid | Apoptosis , p38 MAPK , Parasite |
Asiatic acid (Dammarolic acid) is the aglycone of asiaticoside used in wound healing with antioxidant, anti-inflammatory, and neuroprotective properties. | |||
TN3016 | 4',6,7-Trimethoxyisoflavone | MMP | |
4',6,7-Trimethoxyisoflavone promotes wound healing through NOX2 induction, which leads to collective migration and MMP activation. | |||
TN2077 | (+/-)-Pinocembrin | NSC 43318,(±)-5,7-Dihydroxyflavanone | GPR , Others |
(+/-)-Pinocembrin (NSC-43318), a natural product from axillary pines, is a GPR120 ligand that promotes wound healing in the HaCaT cell line. | |||
TN1079 | Deoxyelephantopin | NF-κB | |
Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling | |||
T1125 | Shikonin | NSC 252844,Isoarnebin 4,(+)-Shikonin,Alkanna Red,C.I. 75535,Anchusa acid | TNF , NF-κB , Chloride channel , HIV Protease , PKM |
Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. Shikonin exhibits antitumor, anti-inflammatory and wound healing activities. | |||
TN6926 | Paeonoside | Others | |
Paeonoside, found in P. suffruticosa, is biologically active and can promote wound healing and migration during osteoblast differentiation. Paeonoside has certain antidiabetic activity and may prevent sepsis and death fr... | |||
TN7082 | Demethyldaphnoretin-7-O-glucoside | Others | |
Demethyldaphnoretin-7-O-glucoside is a natural product that is isolated from Daphne oleoides Schreber subsp. kurdica (DOK). In Turkish traditional medicine, the aerial parts of DOK have been used to treat malaria, rheuma... | |||
TN1641 | (-)-Fenchone | Others , Antioxidant , Antifungal | |
(-)-Fenchone is a bicyclic monoterpenoid widely distributed in plants and can be extracted from Foeniculum vulgare and Peumus boldus. (-)-Fenchone has a wide range of biological activities including antioxidant, wound he... | |||
TN1132 | Procyanidin A2 | IL Receptor , TNF , transporter , Antibacterial | |
Procyanidin A2 is a potential precursor of 5-(3',4'-dihydroxyphenyl)-γ-valerolactone, exhibits antioxidant, anti-inflammary, anti-hyperglycemia, and anti-type 2 diabetes activities. Procyanidin A2 demonstrates liver cell... | |||
T3O2749 | L-Leucine | (S)-Leucine,Leu | mTOR |
L-Leucine ((S)-Leucine) is one of nine essential amino acids in humans (provided by food), L-Leucine is important for protein synthesis and many metabolic functions. L-Leucine contributes to regulation of blood-sugar lev... | |||
T5S2347 | Deoxyshikonin | Arnebin 7 | Others , HIF/HIF Prolyl-Hydroxylase , Antibacterial |
1. Deoxyshikonin (Arnebin 7) may be a new drug candidate for wound healing and treatment of lymphatic diseases. 2. Deoxyshikonin enhances the ability of human dermal lymphatic microvascular endothelial cells (HMVEC-dLy) ... | |||
TN6872 | Trypsin | Protease-activated Receptor | |
Trypsin is a serine protease that can be isolated from fish to hydrolyze lysine or arginine carboxy-side proteins. With the anti-inflammatory activity, Trypsin could induce the cell membrane fusion of PDCoV-infected cell... | |||
TN6495 | 3,4-O-dimethylcedrusin | ||
3′,4-O-Dimethylcedrusin can improve wound healing in vivo by stimulating the formation of fibroblasts and collagen. | |||
T13559 | Astragaloside VI | EGFR | |
TN5044 | Specioside | Others | |
Specioside has antioxidant, analgesic, anti-dyspeptic, astringent, liver stimulating and wound healing activities. It ameliorates oxidative stress and promotes longevity in Caenorhabditis elegans. | |||
T81322 | Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside | ||
Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside, isolated from the aerial parts of the fern Ophioglossum vulgatum L., exhibits wound healing activity [1]. | |||
T75694 | Lacto-N-neotetraose | ||
Lacto-N-neotetraose (LNnT), an endogenous metabolite, inhibits TNF-α-induced IL-8 secretion in immature epithelial cells, exhibits anti-inflammatory activity, and enhances wound closure [1] [2] [4]. | |||
T38097 | Antibiotic PF 1052 | ||
Antibiotic PF 1052 is a fungal metabolite originally isolated from Phoma.1,2 It is active against S. aureus, S. parvulus, and C. perfringens (MICs = 3.13, 0.78, and 0.39 μg/ml, respectively), among others.1 It inhibits n... | |||
T78490 | Polygalacturonic acid | Galacturonic acid polymer | |
Polygalacturonic acid (Galacturonic acid polymer), a transparent colloid, constitutes a significant portion of the cell wall. It is employed in the synthesis of silver nanoparticles (AgNPs), serving both as an antioxidan... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPJ-00735 | PDGF-BB Protein, Human, Recombinant | Human | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P... | |||
TMPY-02185 | Coagulation factor XIII B/F13B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ... | |||
TMPJ-00562 | PDGF-BB Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P... | |||
TMPJ-00037 | FGF-2 Protein, Mouse, Recombinant | Mouse | E. coli |
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mo... | |||
TMPY-01061 | FGF-10 Protein, Human, Recombinant | Human | E. coli |
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes... | |||
TMPH-02830 | PLET1 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. | |||
TMPH-02831 | PLET1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. | |||
TMPH-01865 | PLET1 Protein, Human, Recombinant (His) | Human | E. coli |
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. PLET1... | |||
TMPH-01866 | PLET1 Protein, Human, Recombinant (His & Myc) | Human | Baculovirus Insect Cells |
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. PLET1... | |||
TMPH-02594 | MMP-13 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the hig... | |||
TMPH-01297 | DDR1 Protein, Human, Recombinant (aa 21-417, His) | Human | HEK293 Cells |
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival ... | |||
TMPH-01974 | Prothrombin Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wo... | |||
TMPK-01334 | EMMPRIN/CD147 Protein, Canine, Recombinant (His) | Canine | HEK293 Cells |
CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiolo... | |||
TMPY-02838 | FGFBP3 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
FGFBP3 is a member of the fibroblast growth factor-binding protein family. Members of this family binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. Fibroblast growth factors (FGFs) are impo... | |||
TMPJ-00271 | SMAD3 Protein, Human, Recombinant (His & Flag) | Human | E. coli |
Mothers against decapentaplegic homolog 3(SMAD3) is a cytoplasm protein which belongs to the dwarfin/SMAD family. Smad proteins undergo rapid nuclear translocation upon stimulation by transforming growth factor and in so... | |||
TMPH-03599 | Streptopain Protein, S. pyogenes, Recombinant (His & SUMO) | Streptococcus pyogenes | E. coli |
Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelia... | |||
TMPK-00367 | MMP-9 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demon... | |||
TMPK-00503 | MMP-9 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demon... | |||
TMPY-04801 | Fibromodulin Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Fibromodulin (FMOD), an ECM small leucine-rich proteoglycan (SLRP), was reported to promote angiogenesis not only during wound healing, but also in optical and cutaneous angiogenesis-dependent diseases. The autocrine FM... | |||
TMPH-02835 | PDGFD Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role ... | |||
TMPH-03598 | Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO) | Streptococcus pyogenes | E. coli |
Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelia... | |||
TMPK-01043 | VEGFC Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet... | |||
TMPK-00368 | MMP-9 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demon... | |||
TMPY-01190 | INHBB Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two ... | |||
TMPY-01846 | Activin A Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two ... | |||
TMPK-01044 | VEGFC Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet... | |||
TMPJ-00447 | MMP-3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue rem... | |||
TMPJ-00771 | TGF beta 1 Protein, Mouse/Rat, Recombinant | Mouse,Rat | HEK293 Cells |
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differen... | |||
TMPY-00371 | STC1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Stanniocalcin-1 (STC1) is a paracrine factor associated with inflammation and carcinogenesis. STC1 is a secreted glycoprotein hormone and involved in various types of human malignancies. Stanniocalcin-1 (STC1), which has... | |||
TMPJ-01433 | Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated | Human | E. coli |
Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components ... | |||
TMPJ-01089 | TFF1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains.TFF1 is an approximately peptide that has an important effect in epithelial regeneration and wound healing... | |||
TMPJ-00012 | CXCL4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-binding sites at the C-terminal region and binds heparin with hi... | |||
TMPY-03419 | SMAD3 Protein, Human, Mouse, Rat, Recombinant (His & GST) | Human,Mouse,Rat | Baculovirus Insect Cells |
SMAD3 belongs to the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD3 is... | |||
TMPY-01484 | THSD1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein that contains one TSP type-1 domain. THSD1 is ... | |||
TMPJ-00304 | ALK-1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10. ALK1 signaling is necessary for angi... | |||
TMPJ-01177 | NOV/CCN3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor... | |||
TMPH-03753 | MYLK Protein, Human, Recombinant (His) | Human | E. coli |
Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phos... | |||
TMPY-02174 | FABP5 Protein, Human, Recombinant | Human | E. coli |
Fatty acid-binding protein, also known as Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, E-FABP and FABP5, is a cytoplasm protein whic... | |||
TMPJ-00534 | HFcgR4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Fcgr4, also known as CD16-2, is one of the receptors for Fc region of IgG which involve in immune responses. Fcgr4 mainly functions in cellular response to lipopolysaccharide, NK T cell proliferation, regulation of senso... | |||
TMPJ-00802 | THBS1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Thrombospondin-1 (TSP-1) is a 150-180kDa calcium-sensitive protein that is secreted as a disulfide-linked homotrimer. TSP-1 regulates a wide range of cellular functions including their interactions with other cells and w... | |||
TMPY-00741 | CXCL4 Protein, Human, Recombinant | Human | E. coli |
Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds w... | |||
TMPJ-00535 | F13A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, ... | |||
TMPY-01680 | Lumican Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Lumican, a prototypic leucine-rich proteoglycan with keratan sulfate side chains, is a major component of the cornea, dermal, and muscle connective tissues. In these bifunctional molecules, the protein moiety binds colla... | |||
TMPY-02246 | HB-EGF Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
Heparin-binding EGF-like growth factor (HBEGF), a member of the EGF family of growth factors, exerts its biological activity through activation of the EGFR and other ErbB receptors. Soluble mature HBEGF is proteolyticall... | |||
TMPY-02760 | CALML3 Protein, Human, Recombinant (His) | Human | E. coli |
Calmodulin-like protein 3 (CALML3) is similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinity, to cellular substrates. Calmodulin-like protein 3 (CALML3) is a ... | |||
TMPH-02524 | Arginase-1/ARG1 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell ... | |||
TMPY-01212 | ADAM12 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The ADAMs (a disintegrin and metalloprotease) comprise a family of multidomain proteins with metalloprotease, cell adhesion, and signaling activities. Human ADAM12, which is implicated in diseases such as cancer, is expr... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L9810 | Anti-Fibrosis Compound Library | 1180 compounds | |
A unique collection of 1180 potential anti-fibrosis compounds, can be used in HTS and HCS; | |||
L4800 | Angiogenesis related Compound Library | 1353 compounds | |
A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS); | |||
L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; | |||
L8500 | HIF-1 Signaling Pathway Compound Library | 1336 compounds | |
A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies; |