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Search Results for " cortical "

ターゲット

70

阻害剤

15

天然化合物

27

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T38776 LP-922056 Wnt/beta-catenin
LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.
T3217 PF-CBP1 hydrochloride PF-CBP1 HCl Epigenetic Reader Domain , Histone Acetyltransferase
PF-CBP1 hydrochloride (PF-CBP1 HCl) is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).It inhibits CREBBP and p300 bromodomains with IC50 of 125 and 363 nM respectively.
T3198L PRE-084 hydrochloride Sigma receptor
PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).
T21460 Teriparatide acetate hPTH 1-34 (acetate salt),Parathar acetate,Forteo Others
Teriparatide acetate (Forteo) is a PHT agonist, with an IC50 of 2 nM in HEK293 cells.Teriparatide acetate is a recombinant form of parathyroid hormone. It is an effective anabolic (i.e., bone growing) agent used to treat...
T12472 Pifithrin-α, p-Nitro, Cyclic PFN-α p53
Pifithrin-α, p-Nitro, Cyclic (PFN-α) (PFN-α) is cell-permeable and active-form inhibitor of p53.
T22517 5,7-Dichlorokynurenic acid 5,7-dichlorokynurenic acid sodium,5,7-DCKA NMDAR
5,7-Dichlorokynurenic acid (5,7-dichlorokynurenic acid sodium) is an NMDA receptor antagonist.
TP2045 CH 275
Potent somatostatin receptor 1 (sst1) agonist; displays selectivity for sst1 (IC50 values are 30.9 nM, 345 nM, > 1 μM, > 10 μM and > 10μM for human sst1, sst3, sst4, sst2 and sst5 respectively). Attenuates somatostatin r...
T21584 CP 465022 iGluR
CP 465022 hydrochloride is a potent, and selective noncompetitive antagonist of AMPA receptor with anticonvulsant activity. CP 465022 hydrochloride inhibits Kainate-induced response with an IC50 of 25 nM in rat cortical ...
T11217 Eplivanserin SR-46349 5-HT Receptor
T14490 Talipexole dihydrochloride Domnin,B-HT 920 dihydrochloride Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal membrane fractions with Ki values of 0.35 μM and 0.22 μM, ...
T11684 Isoguvacine hydrochloride 1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride GABA Receptor
Isoguvacine hydrochloride (1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride) is a GABA receptor agonist. Isoguvacine hydrochloride binds to rat synaptic cortical membranes and activates α1β2γ2S, α2β2γ2S, α3β2γ2...
T69467 Azacosterol IMD760,Diazasterol Others
Azacosterol (Diazasterol) is a DHCR24 inhibitor.Azacosterol undergoes a series of reactions in cortical neurons following oral or intraperitoneal administration.
TP1140L Neuropeptide Y (29-64), amide, human acetate Neuropeptide Y Receptor
Neuropeptide Y (29-64), amide, human acetate is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.
T10162 5-HT3 antagonist 3 5-HT Receptor
5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist. It binds to 5-HT3 receptors in rat brain cortical membranes (Ki: 0.25 nM).
T9691L (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate Thyroid hormone receptor(THR)
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate is a highly potent antagonist of parathyroid hormone (PTH) The Ki value is 69 nM in bovine renal cortical membrane.
T10998 Deriglidole SL 86-0715 Adrenergic Receptor
Deriglidole (SL 86-0715) is a peripheral adrenergic receptor antagonist that is a selective inhibitor of alpha2 receptors. Deriglidole inhibits colistin and Idazoxan but does not show activity against prazosin and rat co...
TP1223L Apamin acetate Apamine acetate,Apamin acetate(24345-16-2 Free base) Potassium Channel
Apamin acetate (Apamine acetate) is a selective Ca2+-activated blocker of K+ (SK) channels, an 18-amino acid peptide neurotoxin found in bee toxins.Apamin acetate enhances synapse growth and regeneration following lacera...
T0939 Phenytoin Diphenylhydantoin,5,5-Diphenylhydantoin Virus Protease , Sodium Channel
Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux from neurons located in the motor cor...
T23394 SR 57227A SR 57227 hydrochloride 5-HT Receptor
SR 57227A (SR 57227 hydrochloride) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier. It has affinities (IC50) varying between 2.8 and 250 nM for 5-HT3 rece...
T3486 3-MATIDA GluR , NMDAR
3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM). 3...
T70540 Pinokalant LOE-908 SARS-CoV , TRP/TRPV Channel
Pinokalant (LOE-908) is a novel non-selective cation channel inhibitor.Pinokalant significantly reduces cortical infarct volume in in vivo experiments, improves the metabolic and electrophysiological status of the ischem...
T26482 A-57696
A-57696 is a cholecystokinin antagonist with selective for cortical CCK-B receptors (IC50 = 25 nM).
T36141 Boscalid Mitochondrial Metabolism
Boscalid is a broad-spectrum carboxamide fungicide that inhibits fungal respiration by binding to the ubiquinone site of mitochondrial complex II/succinate dehydrogenase.1It suppresses mycelial growth ofS. minorby 87 to ...
T0068L Fluphenazine Decanoate Dihydrochloride
Fluphenazine Decanoate Dihydrochloride is an antipsychotic agent, it could block postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia.
T3648 Hypidone hydrochloride YL0919 5-HT Receptor
Hypidone hydrochloride (YL0919) is a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor.
T70916 AGN-190851
AGN-190851 is an alpha-2 adrenoceptor agonist which acts as a water diuretic by inhibiting vasopressin-stimulated cyclic AMP accumulation in cortical collecting tubules in mouse models.
T71554 ARN 14494
ARN 14494 is a potent serine palmitoyltransferase inhibitor (SPT; IC50 = 27.3 nM). ARN 14494 inhibits synthesis of long chain ceramides and dihydroceramides in an in vitro model of Alzheimer's diease. The compound preven...
T8456 GALNON Neuropeptide Y Receptor
Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue properties
T28850 SR57227A SR 57227A,SR-57227A
SR 57227A is a highly selective of peripheral and central 5-HT3 receptors and an inhibitor of NMDA receptor-mediated responses in rat cortical pyramidal cells. It exhibits anti-depressant like effects in rats and decreas...
TP1338 Neuropeptide Y (29-64), amide, human TFA
Neuropeptide Y (29-64), amide, human (TFA) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.It is showed that Neuropeptide Y (29-64), amide, human (TFA) is able to prot...
T38610 Pirepemat IRL752
Pirepemat (IRL752) is a cortical-preferring catecholamine agent that enhances cognition. It is utilized in the investigation of Parkinson's disease.
T36446 Neuropeptide Y (human) (TFA)
Neuropeptide Y (human) TFA, a compound implicated in Alzheimer's disease (AD), exhibits protective effects against β-Amyloid toxicity in rat cortical neurons.
T60950 Pirepemat fumarate
Pirepemat (IRL752) fumarate can be used in Parkinson's disease study. Pirepemat is a cortical-preferring catecholamine transmission- and cognition-promoting agent [1] [2].
T40510 Ac-RYYRWK-NH2 TFA Ac-RYYRWK-NH2 TFA
Ac-RYYRWK-NH2 is a highly effective and specific partial agonist for the nociceptin receptor (NOP). It demonstrates a remarkable affinity for rat cortical membranes ORL1, with [3H]Ac-RYYRWK-NH2 exhibiting a Kd value of 0...
T71733 VU0606170
VU0606170 is a slack channels inhibitor and was shown to successfully decrease the malfunctioning spontaneous firing rate of cortical neurons, providing a potential avenue for achieving an anti-epileptic effect not previ...
T16155 MSN-125 Akt
MSN-125 effectively inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons protect primary neurons against glutamate excitotoxicity. MSN-125 is an effective Bax and Bak oligomerization in...
T37203 CCK (26-30) (sulfated)
CCK (26-30) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. The sulfated form of CCK (26-30) inhibits binding...
T0068L2 Fluphenazine free base Siqualine,Fluphenazine,Fluorophenazine,Fluorphenazine,Triflumethazine,Fluorfenazine
Flufenazine is an antipsychotic drug. It is used to treat chronic mental illnesses such as schizophrenia. Flufenazine works by blocking postsynaptic dopamine D2 receptors in the limbic system, cortical system, and basal ...
T29809 AL-1 AL 1,AL1
AL-1 is a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin found in developing tectum. It can mediate the bundling of cortical axons and repel the axonal growth of retinal ganglia axons. It exists in a variet...
T73408 Immepip
Immepip, a H3 agonist, has been shown to attenuate cortical histamine release and is utilized in the research of neurological diseases.
T79784 VU6004909
VU6004909 is a positive allosteric modulator of the mGlu5 receptor (pEC50: 7.59), exhibiting antipsychotic-like effects. It has the capability to reverse MK801-induced cortical hyperactivity and cognitive deficits [1] [2...
T75730 [D-Arg25]-Neuropeptide Y (human)
[D-Arg25]-Neuropeptide Y (human) ([D-Arg25] NPY), a Y1 receptor selective agonist, plays a role in Alzheimer's disease (AD) and safeguards rat cortical neurons from β-Amyloid toxicity [1].
T29002 Trazium Esilate EGYT3615,EGYT-3615,EGYT 3615
Trazium esilate is an adrenergic receptor antagonist. Trazium esilate is a weak displacer on a1-, a2- and D2-receptors, however, it induced a2-receptor desenzitization after repeated treatment. It had no influence on rat...
T35551 Gallocyanine
Gallocyanine is a small molecule blue dye used to stain nuclei. It is known to inhibit Dickkopf-1 (Dkk1), an antagonist of the Wnt pathway. Gallocyanine can disrupt the interaction of Dkk1 with its receptor LRP5/6 (IC50 ...
T81899 LY836 iGluR
LY836 is an orally active, neuroprotective compound that effectively inhibits the PSD95-nNOS association in cortical neurons. It has potential applications in the study of ischemic stroke [1].
T37205 CCK (26-31) (sulfated)
CCK (26-31) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. The sulfated form of CCK (26-31) inhibits binding...
T21875 CP-465022 (maleate)
CP-465022 Maleate is a potent, selective, noncompetitive AMPA receptor antagonist with anticonvulsant activity. It effectively counters the Kainate-induced response in rat cortical neurons, exhibiting an IC 50 of 25 nM. ...
TP2060 Conantokin G
GluN2B (formally NR2B) selective, competitive antagonist of the NMDA receptor. Blocks NMDA-evoked current in mouse cortical neurons (IC50 = 480 nM); also inhibits NMDA-evoked responses in oocytes expressing GluN2B (forma...
T37661 LY 2886721 Hydrochloride
Potent and selective β-secretase (BACE) inhibitor (IC50 values are 10.2 and 20.3 nM for human BACE2 and BACE1, respectively). Displays >5,000-fold selectivity for BACE over other proteases including cathepsin D, pepsin a...
T7352L Pridopidine hydrochloride ASP2314 HCl,Pridopidine HCl,FR310826,ASP-2314 hydrochloride
Pridopidine Hydrochloride is a dopaminergic stabilizer that has been shown to improve a variety of neurological and psychiatric disorders, including Huntington's disease. Pridopidine Hydrochloride stabilizes psychomotor ...

Compounds

LP-922056
T38776
Synonym:
Target: Wnt/beta-catenin
PF-CBP1 hydrochloride
T3217
Synonym: PF-CBP1 HCl
Target: Epigenetic Reader Domain, Histone Acetyltransferase
PRE-084 hydrochloride
T3198L
Synonym:
Target: Sigma receptor
Teriparatide acetate
T21460
Synonym: hPTH 1-34 (acetate salt),Parathar acetate,Forteo
Target: Others
Pifithrin-α, p-Nitro, Cyclic
T12472
Synonym: PFN-α
Target: p53
5,7-Dichlorokynurenic acid
T22517
Synonym: 5,7-dichlorokynurenic acid sodium,5,7-DCKA
Target: NMDAR
CH 275
TP2045
Synonym:
Target:
CP 465022
T21584
Synonym:
Target: iGluR
Eplivanserin
T11217
Synonym: SR-46349
Target: 5-HT Receptor
Talipexole dihydrochloride
T14490
Synonym: Domnin,B-HT 920 dihydrochloride
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Isoguvacine hydrochloride
T11684
Synonym: 1,2,3,6-tetrahydro-4-pyridinecarboxylic acid hydrochloride
Target: GABA Receptor
Azacosterol
T69467
Synonym: IMD760,Diazasterol
Target: Others
Neuropeptide Y (29-64), amide, human acetate
TP1140L
Synonym:
Target: Neuropeptide Y Receptor
5-HT3 antagonist 3
T10162
Synonym:
Target: 5-HT Receptor
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate
T9691L
Synonym:
Target: Thyroid hormone receptor(THR)
Deriglidole
T10998
Synonym: SL 86-0715
Target: Adrenergic Receptor
Apamin acetate
TP1223L
Synonym: Apamine acetate,Apamin acetate(24345-16-2 Free base)
Target: Potassium Channel
Phenytoin
T0939
Synonym: Diphenylhydantoin,5,5-Diphenylhydantoin
Target: Virus Protease, Sodium Channel
SR 57227A
T23394
Synonym: SR 57227 hydrochloride
Target: 5-HT Receptor
3-MATIDA
T3486
Synonym:
Target: GluR, NMDAR
Pinokalant
T70540
Synonym: LOE-908
Target: SARS-CoV, TRP/TRPV Channel
A-57696
T26482
Synonym:
Target:
Boscalid
T36141
Synonym:
Target: Mitochondrial Metabolism
Fluphenazine Decanoate Dihydrochloride
T0068L
Synonym:
Target:
Hypidone hydrochloride
T3648
Synonym: YL0919
Target: 5-HT Receptor
AGN-190851
T70916
Synonym:
Target:
ARN 14494
T71554
Synonym:
Target:
GALNON
T8456
Synonym:
Target: Neuropeptide Y Receptor
SR57227A
T28850
Synonym: SR 57227A,SR-57227A
Target:
Neuropeptide Y (29-64), amide, human TFA
TP1338
Synonym:
Target:
Pirepemat
T38610
Synonym: IRL752
Target:
Neuropeptide Y (human) (TFA)
T36446
Synonym:
Target:
Pirepemat fumarate
T60950
Synonym:
Target:
Ac-RYYRWK-NH2 TFA
T40510
Synonym: Ac-RYYRWK-NH2 TFA
Target:
VU0606170
T71733
Synonym:
Target:
MSN-125
T16155
Synonym:
Target: Akt
CCK (26-30) (sulfated)
T37203
Synonym:
Target:
Fluphenazine free base
T0068L2
Synonym: Siqualine,Fluphenazine,Fluorophenazine,Fluorphenazine,Triflumethazine,Fluorfenazine
Target:
AL-1
T29809
Synonym: AL 1,AL1
Target:
Immepip
T73408
Synonym:
Target:
VU6004909
T79784
Synonym:
Target:
[D-Arg25]-Neuropeptide Y (human)
T75730
Synonym:
Target:
Trazium Esilate
T29002
Synonym: EGYT3615,EGYT-3615,EGYT 3615
Target:
Gallocyanine
T35551
Synonym:
Target:
LY836
T81899
Synonym:
Target: iGluR
CCK (26-31) (sulfated)
T37205
Synonym:
Target:
CP-465022 (maleate)
T21875
Synonym:
Target:
Conantokin G
TP2060
Synonym:
Target:
LY 2886721 Hydrochloride
T37661
Synonym:
Target:
Pridopidine hydrochloride
T7352L
Synonym: ASP2314 HCl,Pridopidine HCl,FR310826,ASP-2314 hydrochloride
Target:
1 2
カタログ番号 製品名 別名 ターゲット
TCA2511 11Beta-hydroxyprogesterone Sodium Channel
The progesterone derivatives 11 alpha- and 11 beta-hydroxyprogesterone are potent inhibitors of 11 beta-hydroxysteroid dehydrogenase (isoforms 1 and 2) in vitro and can confer mineralocorticoid activity on corticosterone...
TN5131 Tetrahydrocannabivarin THCV,delta9-Tetrahydrocannabivarin,CRM,Tetrahydrocannavarin Cannabinoid Receptor
Tetrahydrocannabivarin (CRM) is a neutral cannabis receptor subtype (CB1) receptor antagonist, it can increases neural responding to rewarding and aversive stimuli, this effect profile suggests therapeutic activity in ob...
T6S1418 Praeruptorin C Antioxidant , Calcium Channel
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ...
T5S2129 Sciadopitysin TNF , NF-κB
Sciadopitysin may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis.Sciadopitysin shows protective effects on antimycin A-induced toxicity in o...
TN2257 Tanshinone IIB BCL , Caspase , P-gp
Co-treatment with Tanshinone IIB (TSB) significantly inhibits the DNA laddering, cytotoxicity and apoptosis of rat cortical neurons induced by staurosporine in a concentration-dependent manner; TSB also suppresses the el...
TN2037 Paeonilactone C Others
Paeonilactone C significantly protects primary cultures of rat cortical cells against H2O2-induced neurotoxicity.
TN5169 Traxillaside 香榧 Others
Traxillaside has significant neuroprotective activities against glutamate-induced toxicity in primary cultures of rat cortical cells .
TN2036 Paeonilactone B (+)-Paeonilactone B NADPH-oxidase
Paeonilactone B ((+)-Paeonilactone B), a monoterpenoid from Paeonilactone, has neuroprotective activity, inhibits oxidative stress, and suppresses H2O2-induced neurotoxicity in rat cortical cells.
T83288 5-Hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone
Hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone is a neuroprotective agent that exhibits marked neuroprotective activity by mitigating glutamate-induced neurotoxicity in primary rat cortical cell cultures [1].
TN3771 Dasycarpol Others
Dasycarpol(9beta-Hydroxyfraxinellone) shows significant neuroprotective activity against glutamate-induced neurotoxicity in primary cultures of rat cortical cells at a concentration of 0.1 microM. Dasycarpol also shows m...
TN4286 Isodunnianol NOS , NF-κB , ROS , AChR
Isodunnianol exhibits anti-AChE activity with an IC50 value of 13.0 uM; it also exhibits neurite outgrowth-promoting activity at the concentration ranging from 0.1 to 10 uM in the primary cultured rat cortical neurons. I...
T16846 Sauristolactam Saurolactam Others
Sauristolactam inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation. Sauristolactam, a natural aristolactam isolated f...
TN3444 Aristolactam BII HIV Protease
Aristolactam BII exhibits antimicrobial and antiinflammatory activity, it shows significant activity towards DPPH radical scavenging and potent inhibitory effects against tyrosinase mushroom. Aristolactam BII also exerts...
T75890 Conantokin G TFA
Conantokin G TFA, a 17-amino-acid peptide, serves as a potent, selective, and competitive antagonist of N-Methyl-D-Aspartate (NMDA) receptors, effectively inhibiting NMDA-evoked currents in murine cortical neurons at an ...
TN5164 Trans-Hinokiresinol IL Receptor , TNF , NOS , LTR
Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphylaxis reaction. Hinokiresinol (trans-hinokiresinol) and nyaso...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-05510 BDNF Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. B...
TMPY-05028 NOTCH2NL Protein, Human, Recombinant (mFc) Human HEK293 Cells
NOTCH2NLA (Notch 2 N-Terminal Like A) is a Protein Coding gene. NOTCH2NL, human-specific paralogs of the NOTCH2 receptor, stood out for their ability to promote cortical progenitor maintenance. It belongs to the NOTCH fa...
TMPK-00810 TPA Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predomin...
TMPH-01669 Metallothionein-3/MT3 Protein, Human, Recombinant (His & SUMO) Human E. coli
Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro.
TMPH-03375 Stathmin-2 Protein, Rat, Recombinant (His) Rat E. coli
Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from ...
TMPH-01610 LINGO1 Protein, Human, Recombinant (His) Human E. coli
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of ...
TMPH-02595 Collectrin Protein, Mouse, Recombinant (His & Myc & SUMO) Mouse E. coli
Plays an important role in amino acid transport by acting as binding partner of amino acid transporters SLC6A18 and SLC6A19, regulating their trafficking on the cell surface and their activity. May also play a role in tr...
TMPY-04423 CAMKI gamma/CAMK1G Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Calmodulin-Dependent Protein Kinase (CaM Kinase) is a kind of protein phosphorylate multiple downstream targets. Concentration of cytosolic calcium functions as a second messenger that mediates a wide range of cellular r...
TMPH-02187 Tenascin Protein, Human, Recombinant (E. coli, His) Human E. coli
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown o...
TMPH-00169 PBP 3 Protein, Bacillus subtilis, Recombinant (His) Bacillus subtilis E. coli
Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Probably required for both cortical and vegetative peptidoglycan synthesis. Although not usually required for cell division, in the ab...
TMPH-02753 LINGO1 Protein, Mouse, Recombinant (His) Mouse E. coli
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of ...
TMPJ-01148 NRN1L Protein, Human, Recombinant (His) Human HEK293 Cells
Neuritin-like protein belongs to the neuritin family. Neuritin is a GPI-anchored protein that promotes neurite outgrowth and branching of neuritic processes in primary hippocampal and cortical cells. Neuritin expression ...
TMPH-01729 Myosin-9/MYH9 Protein, Human, Recombinant (GST) Human E. coli
Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Required for cortical actin clearance prior to oocyte exocytosis. Promotes cell motility in...
TMPJ-00079 IL-11 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate ...
TMPY-02847 Moesin Protein, Human, Recombinant (aa 1-346, His) Human E. coli
Moesin is a member of the ERM family which includes ezrin and radixin. ERM proteins, highly related members of the larger protein 4.1 superfamily, can exist in an active or inactive conformation. It seems that ERM protei...
TMPY-00286 Neuropeptide Y Protein, Human, Recombinant (hFc) Human HEK293 Cells
NPY (Neuropeptide Y) is a Protein Coding gene. This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress ...
TMPJ-00671 FABP7 Protein, Human, Recombinant (His) Human E. coli
Fatty Acid-Binding Protein 7 (FABP7) is a cytoplasm protein that belongs to the Fatty-acid Binding Protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytopl...
TMPY-01712 C1QB Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulon...
TMPY-02885 CD1B Protein, Human, Recombinant (hFc) Human HEK293 Cells
CD1B contains 1 Ig-like (immunoglobulin-like) domain and belongs to the CD1 family. CD1 family members are transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) protein...
TMPJ-00385 CDH6 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Cadherin-6 (CDH6) is a type-II classic cadherin cell-cell adhesion molecules, which are expressed in graded or areal patterns, as well as layer-specific patterns, in the cortical plate. Human Cadherin-6 is synthesized as...
TMPY-02579 NRN1 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Neuritin 1 (NRN1) is a member of the neuritin family. Neuritin is a glycosylphosphatidylinositol-anchored protein induced by neural activity. It is expressed in postmitotic-differentiating neurons of the developing nervo...
TMPY-02106 GAP43 Protein, Human, Recombinant (His) Human HEK293 Cells
Neuromodulin, also known as Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-5, pp46 and GAP43, is a cell membrane protein which belongs to theneuromodulin family. Neuromodulin / G...
TMPY-02491 LRRN3 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Leucine-rich repeat neuronal protein 3, also known as neuronal leucine-rich repeat protein 3 (NLRR-3), is a member of the leucine-rich (LRR) family whose members have significant functions in neural development. Leucine-...
TMPY-02001 RTN4 Protein, Human, Recombinant (GST) Human E. coli
Reticulon-4, also known as Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5 and RTN4, is a multi-pass membrane protein that...
TMPH-03764 YAP1 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor su...
TMPY-01249 Cathepsin V Protein, Human, Recombinant (His) Human HEK293 Cells
Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and t...
TMPH-02613 ATF-5 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific respo...
BDNF Protein, Mouse, Recombinant (His)
TMPY-05510
Species: Mouse
Expression System: HEK293 Cells
NOTCH2NL Protein, Human, Recombinant (mFc)
TMPY-05028
Species: Human
Expression System: HEK293 Cells
tPA Protein, Mouse, Recombinant (His)
TMPK-00810
Species: Mouse
Expression System: HEK293 Cells
Metallothionein-3/MT3 Protein, Human, Recombinant (His & SUMO)
TMPH-01669
Species: Human
Expression System: E. coli
Stathmin-2 Protein, Rat, Recombinant (His)
TMPH-03375
Species: Rat
Expression System: E. coli
LINGO1 Protein, Human, Recombinant (His)
TMPH-01610
Species: Human
Expression System: E. coli
Collectrin Protein, Mouse, Recombinant (His & Myc & SUMO)
TMPH-02595
Species: Mouse
Expression System: E. coli
CAMKI gamma/CAMK1G Protein, Human, Recombinant (His & GST)
TMPY-04423
Species: Human
Expression System: Baculovirus Insect Cells
Tenascin Protein, Human, Recombinant (E. coli, His)
TMPH-02187
Species: Human
Expression System: E. coli
PBP 3 Protein, Bacillus subtilis, Recombinant (His)
TMPH-00169
Species: Bacillus subtilis
Expression System: E. coli
LINGO1 Protein, Mouse, Recombinant (His)
TMPH-02753
Species: Mouse
Expression System: E. coli
NRN1L Protein, Human, Recombinant (His)
TMPJ-01148
Species: Human
Expression System: HEK293 Cells
Myosin-9/MYH9 Protein, Human, Recombinant (GST)
TMPH-01729
Species: Human
Expression System: E. coli
IL-11 Protein, Mouse, Recombinant (hFc)
TMPJ-00079
Species: Mouse
Expression System: HEK293 Cells
Moesin Protein, Human, Recombinant (aa 1-346, His)
TMPY-02847
Species: Human
Expression System: E. coli
Neuropeptide Y Protein, Human, Recombinant (hFc)
TMPY-00286
Species: Human
Expression System: HEK293 Cells
FABP7 Protein, Human, Recombinant (His)
TMPJ-00671
Species: Human
Expression System: E. coli
C1QB Protein, Human, Recombinant (His)
TMPY-01712
Species: Human
Expression System: Baculovirus Insect Cells
CD1B Protein, Human, Recombinant (hFc)
TMPY-02885
Species: Human
Expression System: HEK293 Cells
CDH6 Protein, Human, Recombinant (hFc)
TMPJ-00385
Species: Human
Expression System: HEK293 Cells
NRN1 Protein, Human, Recombinant (His)
TMPY-02579
Species: Human
Expression System: Baculovirus Insect Cells
GAP43 Protein, Human, Recombinant (His)
TMPY-02106
Species: Human
Expression System: HEK293 Cells
LRRN3 Protein, Human, Recombinant (His)
TMPY-02491
Species: Human
Expression System: Baculovirus Insect Cells
RTN4 Protein, Human, Recombinant (GST)
TMPY-02001
Species: Human
Expression System: E. coli
YAP1 Protein, Human, Recombinant (His)
TMPH-03764
Species: Human
Expression System: P. pastoris (Yeast)
Cathepsin V Protein, Human, Recombinant (His)
TMPY-01249
Species: Human
Expression System: HEK293 Cells
ATF-5 Protein, Mouse, Recombinant (His & Myc)
TMPH-02613
Species: Mouse
Expression System: E. coli