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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TP1277 | Bradykinin | Endogenous Metabolite , Bradykinin Receptor | |
Bradykinin is an inflammatory mediator. It is a peptide that causes blood vessels to dilate (enlarge) via the release of prostacyclin, nitric oxide, and Endothelium-Derived Hyperpolarizing Factor. Bradykinin is a physiol... | |||
T7017 | WNK463 | Serine/threonin kinase | |
WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4). | |||
T11666 | IPR-803 | Serine/threonin kinase | |
IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity. IPR-803 binds directly to uPAR with a Ki of 0.2 μM. | |||
T10547 | BioE-1115 | Serine/threonin kinase , Casein Kinase | |
T8350 | TPCK | Proteasome | |
TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis | |||
T4058 | R-IMPP | Others , Serine/threonin kinase | |
R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin. | |||
T11885 | LSP-249 | Others | |
LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell. | |||
T13257 | Upamostat | PAI-1 , Serine/threonin kinase , Serine Protease | |
Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor. | |||
T4524 | SBC-110736 | SBC110736 | Others , Serine/threonin kinase |
SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor | |||
T9920 | Evolocumab | Others | |
Evolocumab is a human IgG2 monoclonal antibody that binds to human PCSK9 Proprotein Convertase Subtilisin Kexin Type 9). | |||
T13408 | ZK824190 | Others , Serine Protease | |
ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA) as a potential treatment for multiple sclerosis(IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively). | |||
T14358 | Avoralstat | BCX4161 | Others |
Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema. | |||
T9276 | SBC-115337 | Others , Serine/threonin kinase | |
SBC-115337 is a PCSK9 inhibitor. | |||
T5456 | WNK-IN-11 | Allosteric WNK Kinase Inhibitor | Serine/threonin kinase |
WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM) | |||
T8866 | GW779439X | Apoptosis , Antibacterial , CDK , Aurora Kinase | |
GW779439X is an inhibitor of CDK. | |||
T8645 | PF-06446846 | Others | |
PF 06446846 is a potent and selective PCSK9 inhibitor | |||
T2626 | SBC-115076 | SBC115076 | Others , Serine/threonin kinase |
SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist. | |||
T8676 | FOY 251 | Others , Serine/threonin kinase , SARS-CoV | |
FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate. | |||
T6370 | AEBSF hydrochloride | AEBSF HCl,Pefabloc SC | Thrombin , Serine Protease , Influenza Virus |
AEBSF hydrochloride (Pefabloc SC) is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin. | |||
T8362 | Benzamidine hydrochloride | Benzamidine HCl | Serine/threonin kinase , Serine Protease |
Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively). | |||
T31206 | Darexaban | YM 150,Darexaban, Tanexaban,YM150 | Factor Xa |
Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothrombin activity at the site of blood clot (thrombus) formati... | |||
T3359 | Aprotinin | Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin | Others , Serine Protease , Influenza Virus , Proteasome |
Aprotinin (Traskolan) a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activat... | |||
T2392 | Nafamostat mesylate | FUT-175 | Apoptosis , Serine/threonin kinase , SARS-CoV , Serine Protease |
Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. | |||
T5125 | LY3200882 | TGF-beta/Smad | |
LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI). | |||
T19763 | Cetraxate hydrochloride | DV-1006,DV 1006,Cetraxate HCl,DV1006 | Serine/threonin kinase |
Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect. | |||
T8936 | Proteinase K | proteinase K for tritirachium album,Protease K | Others |
Proteinase K (proteinase K for tritirachium album) is a nonspecific serine protease that is useful for general digestion of proteins. It is active in the presence of SDS or urea and over a wide range of pH (4-12), salt c... | |||
T50103 | NFAT Inhibitor-2 | Others | |
NFAT Inhibitor-2 is a compound used as a molecular building block. | |||
T2391 | Camostat mesylate | FOY-S980,FOY305,Camostat mesilate | Serine/threonin kinase , SARS-CoV , Sodium Channel |
Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function. | |||
T3041 | ALK inhibitor 2 | FAK , ALK | |
ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase. | |||
T10285 | ALK inhibitor 1 | FAK , IGF-1R , ALK | |
ALK inhibitor 1 is a selective ALK kinase inhibitor. | |||
T1911 | Afuresertib | GSK2110183C,GSK2110183 | ROCK , Akt , PKC |
Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. | |||
T9993 | SBP-3264 | Others | |
SBP-3264 is a novel inhibitor of serine/threonine-protein kinases 3 and 4 (STK3 and STK4). | |||
T62684 | Lartesertib | ATM Inhibitor-5,M4076 | ATM/ATR |
Lartesertib (ATM Inhibitor-5) is an inhibitor of the serine/threonine protein kinase ATM with potential anticancer activity and can be used to study lung cancer. | |||
T6095 | JNJ-38877605 | c-Met/HGFR | |
JNJ-38877605 is an ATP-competitive c-Met inhibitor (IC50: 4 nM), 600-fold selective for c-Met than 200 other tyrosine and serine-threonine kinases. | |||
T11942 | MAP4K4-IN-3 | Compound 17 | MAPK |
MAP4K4-IN-3 (Compound 17) may be a viable target for antidiabetic agents, a serine/threonine protein kinase. | |||
T9589 | SI-113 | SGK | |
SI-113 is a potent and selective inhibitor of SGK1, a serine/threonine protein kinase, that modulates several oncogenic signaling cascades. | |||
T81417 | PP5-IN-1 | Apoptosis , Phosphatase | |
PP5-IN-1 is a potent and competitive serine/threonine protein phosphatase-5 (PP5) inhibitor with potential anticancer activity that induces apoptosis in cancer cells. | |||
T7151 | GSK2982772 | RIP kinase | |
GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively. | |||
T10727 | Cdc7-IN-5 | CDK | |
Cdc7-IN-5 is a potent inhibitor of Cdc7 kinase. Cdc7, a serine-threonine protein kinase enzyme, is essential for the initiation of DNA replication in the cell cycle. | |||
T77333L | (Iso)-BMT-124110 Formate | (R)-N-(8-((2-amino-2,4-dimethylpentyl)oxy)-5H-chromeno[3,4-c]pyridin-2-yl)acetamide Formate(1679370-98-9 Free base) | AAK1 (AP2 associated kinase 1) |
(Iso)-BMT-124110 Formate has an inhibitory effect on the protein serine/threonine kinase AAK, and is used in the treatment of Parkinson's disease, schizophrenia, neuropathic pain, and Alzheimer's disease. | |||
T60688 | MKI-1 | MASTL Kinase Inhibitor-1 | Others |
MKI-1 (MASTL Kinase Inhibitor-1) is an inhibitor of MASTL (microtubule-associated serine/threonine kinase-like, IC50= 9.9 μM). MKI-1 exerts radiosensitizer and antitumor activities through PP2A activation in breast cance... | |||
T34973 | Tyrphostin 8 | 4-Hydroxybenzylidenemalononitrile | EGFR , GTPase |
Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits protein serine/threonine calmodulin phosphatases (IC50=21 μM), enhances ... | |||
TP1875L | CDK2 acetate(255064-79-0 free base) | Others | |
CDK2 acetate is a member of the eukaryotic S/T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate. | |||
T6496 | Vactosertib | TEW-7197,EW-7197 | ALK , TGF-beta/Smad |
Vactosertib (EW-7197) is an orally bioavailable inhibitor of the serine/threonine kinase, transforming growth factor (TGF)-beta receptor type 1 (TGFBR1), also known as activin receptor-like kinase 5 (ALK5), with potentia... | |||
T3980 | Su1498 | Tyrphostin SU 1498,AG 1498 | VEGFR |
Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1,... | |||
T6904 | Necrosulfonamide | (E)-Necrosulfonamide | MLK |
(E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during nec... | |||
T10406 | Tuvusertib | M1774,ATR inhibitor 1 | Apoptosis , ATM/ATR , Others , Chk |
Tuvusertib (M1774) is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 µΜ) with selective and potentially antitumor activity.Tuvusertib selectively inhibits ATR activity and blocks... | |||
T37207L | Cdk5 Substrate acetate | CDK | |
Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau. Cdk5 Substrate aceta... | |||
T9542 | NS3861 | AChR | |
NS3861 is an agonist of nicotinic acetylcholine receptors (nAChRs) and bind with high affinity to heteromeric α3β4 and α4β2 nAChRs. NS3861 displays the β-subunit preference and a complete lack of activation at α4-contain... | |||
T37185 | D-(-)-3-Phosphoglyceric acid disodium | 3-Phospho-D-glyceric acid disodium | Others |
D-(-)-3-Phosphoglyceric acid disodium (3-Phospho-D-glyceric acid disodium) is an intermediate in several biological pathways, most notably glycolysis/gluconeogenesis and the biosynthesis of serine, glycine, and threonine... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN2082 | Pinostrobin | Beta Amyloid , IL Receptor , Serine/threonin kinase , TNF | |
Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppress... | |||
T5S0689 | Demethylwedelolactone | Serine Protease | |
Demethylwedelolactone is a natural product isolated from Eclipta alba, has trypsin inhibitory effect an IC50 of 3.0 μM. it exerts anti-invasive growth effect on breast cancer cells. | |||
T7444 | 6-(Dimethylamino)purine | N,N-Dimethyladenine | Serine/threonin kinase , CDK |
6-(Dimethylamino)purine (N,N-Dimethyladenine) is a serine threonine protein kinase and CDK inhibitor | |||
T4915 | β-Glycerophosphate disodium salt hydrate | Phosphatase , Endogenous Metabolite | |
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It func... | |||
T4713 | Phosphorylcholine chloride calcium salt tetrahydrate | Phosphocholine chloride calcium salt tet,CalciuM Phosphorylcholine Tetrahydrate | Others , Endogenous Metabolite |
Phosphorylcholine chloride calcium salt tetrahydrate (Phosphocholine chloride calcium salt tet) is a small haptenic molecule, is found in a wide variety of organisms. Human hepatic tumors undergo an elevation in the conc... | |||
T4839 | Ac-Ala-OH | N-Acetylalanine,N-Acetyl-L-alanine | Others , Endogenous Metabolite |
Ac-Ala-OH (N-Acetyl-L-alanine) is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4 chain, HIV-1 Rev binding pro... | |||
T4825 | D-(+)-Xylose | D(+)-Xylose,(+)-Xylose,Wood sugar | Endogenous Metabolite |
D-(+)-Xylose (Wood sugar) is an aldopentose - a monosaccharide containing five carbon atoms and an aldehyde functional group. It has chemical formula C5H10O5 and is 40% as sweet as sucrose. Xylose is also found in mucopo... | |||
T19365 | Hydroxypyruvic acid | 3-Hydroxypyruvic acid,β-Hydroxypyruvic acid | Others |
Hydroxypyruvic acid is an intermediate in the metabolism of glycine, serine, and threonine. It is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. | |||
T16381 | Okadaic acid | Others | |
Okadaic acid is a non-comepetitive, selective and reversible serine/threonine-specific protein phosphatases 1 (PP1), PP2A, and PP3 inhibitor (IC50s: 10-15 nM, 0.5 nM, and 4 nM, respectively). Okadaic acid is extracted fr... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-01059 | BMPR2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
BMPR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.6 kDa and the accession number is Q13873. | |||
TMPY-04407 | LOK Protein, Human, Recombinant (His) | Human | E. coli |
Serine / threonine-protein kinase 1, also known as Lymphocyte-oriented kinase, STK1 and LOK, belongs to the protein kinase superfamily, STE Ser / Thr protein kinase family and STE2 subfamily. Protein kinases constitute a... | |||
TMPY-04466 | STK40 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
STK40 is localized to both the cytoplasm and the nucleus. It is ubiquitously expressed. Mechanistically, Stk40 interacts with Rcn2, which also activates Erk1/2 to induce ExEn specification in mouse ESCs. Stk40 is able to... | |||
TMPY-04374 | MST4 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
MST4, also known as mammalian STE2-like protein kinase 4, is a novel member of the germinal center kinase subfamily of human Ste2-like kinases and is closely related to MST3. The 416 amino acid full-length MST4 contains ... | |||
TMPY-04468 | STK16 Protein, Human, Recombinant (His & NusA) | Human | E. coli |
Serine/threonine-protein kinase 16, also known as myristoylated and palmitoylated serine/threonine-protein kinase, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, MPSK1 and STK16, is a membrane protein that is... | |||
TMPY-04398 | MST1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4/Hippo pathway may have important therapeutic implications for cancer. The t... | |||
TMPH-00340 | ATG1 Protein, Candida glabrata, Recombinant (His) | Candida glabrata | E. coli |
ATG1 Protein, Candida glabrata, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 38.4 kDa and the accession number is Q6FL58. | |||
TMPH-03456 | CAK1 Protein, S. cerevisiae, Recombinant (His & Myc) | Saccharomyces cerevisiae | Baculovirus Insect Cells |
CAK1 Protein, S. cerevisiae, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 46.1 kDa and the accession number is P43568. | |||
TMPH-03457 | CAK1 Protein, S. cerevisiae, Recombinant (E. coli, His & Myc) | Saccharomyces cerevisiae | E. coli |
CAK1 Protein, S. cerevisiae, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.6 kDa and the accession number is P43568. | |||
TMPY-05095 | RAF1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
RAF1 gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds direct... | |||
TMPJ-00944 | PPP1CC Protein, Human, Recombinant (His) | Human | E. coli |
Serine/Threonine-Protein Phosphatase PP1-Υ Catalytic Subunit (PPP1CC) is a member of the PPP phosphatase family. It is essential for cell division, participates in the regulation of glycogen metabolism, muscle contractil... | |||
TMPY-04424 | MST3 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. STK24/CCM3-regulated exocytosis pla... | |||
TMPY-02198 | ILKAP Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Integrin-linked kinase-associated serine/threonine phosphatase 2C, also known as ILKAP, is a cytoplasm protein that belongs to the PP2C family. ILKAP contains one PP2C-like domain. ILKAP is widely expressed. Highest leve... | |||
TMPY-00683 | BMPR2 Protein, Human, Recombinant (His & hFc) | Human | HEK293 Cells |
BMPR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 42 kDa and the accession number is Q13873. | |||
TMPJ-00325 | BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His) | Human | HEK293 Cells |
Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A i... | |||
TMPJ-00304 | ALK-1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10. ALK1 signaling is necessary for angi... | |||
TMPH-01171 | CDK5 Protein, Human, Recombinant | Human | E. coli |
CDK5 Protein, Human, Recombinant is expressed in E. coli. | |||
TMPH-01173 | CDK7 Protein, Human, Recombinant | Human | E. coli |
CDK7 Protein, Human, Recombinant is expressed in E. coli. | |||
TMPH-01172 | CDK7 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
CDK7 Protein, Human, Recombinant (His) is expressed in Baculovirus. | |||
TMPJ-00254 | TGF beta 3 Protein, Human/Mouse/Rat, Recombinant | Human,Mouse,Rat | HEK293 Cells |
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes acti... | |||
TMPY-02953 | TEM8/ANTXR1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are ser... | |||
TMPY-04552 | AKT1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to ... | |||
TMPY-04559 | CDC42BPB Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
CDC42BPB is a member of the serine / threonine protein kinase family that contains a Cdc42 / Rsc-binding p21 binding domain similar to that of PAK kinase. The kinase domain of this protein is related to the myotonic dyst... | |||
TMPY-03810 | GALNT2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
GALNT2, also known as GalNAc-T2, is a member of the GalNAc-transferases family. Members of this family transfer an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-link... | |||
TMPY-04565 | SRPK3 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Serine / threonine-protein kinase SRPK3, also known as Muscle-specific serine kinase 1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific kinase 3, Serine / threonine-protein kinase 23, MSSK-1, SRPK3 an... | |||
TMPH-03458 | STE11 Protein, S. cerevisiae, Recombinant | Saccharomyces cerevisiae | E. coli |
Serine/threonine protein kinase required for cell-type-specific transcription and signal transduction in yeast. It is thought that it phosphorylates the STE7 protein kinase which itself, phosphorylates the FUS3 and or KS... | |||
TMPY-04463 | CDKL2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Cyclin-dependent kinase-like 2 (Cdkl2) is a member of cdc2-related serine / threonine protein kinase family and it is found expressed in various brain regions, including the cerebral cortex, entorinal cortex, hippocampus... | |||
TMPY-04420 | TLK1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Tousled-like kinase 1 (or protein kinase ubiquitous, PKU-beta/TLK1) is a serine/threonine protein kinase that is implicated in chromatin remodeling, DNA replication and mitosis. TLK1 has a function important for proper c... | |||
TMPH-02180 | TTBK2 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Serine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother cent... | |||
TMPK-00972 | PK-1/PROK1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
PK-1 (Ac10) is a baculovirus-encoded serine/threonine kinase,a pk-1 knockout AcMNPV failed to produce infectious progeny, while the pk-1 repair virus could rescue this defect.the kinase activity of PK-1 is essential in r... | |||
TMPJ-01109 | EIF4EBP2 Protein, Human, Recombinant (His) | Human | E. coli |
Eukaryotic Translation Initiation Factor 4E-Binding Protein 2 (EIF4EBP2) is a member of the Eukaryotic Translation Initiation Factor 4E Binding Protein Family. EIF4EBP2 regulates eIF4E activity by preventing its assembly... | |||
TMPY-04402 | CSNK1G1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Casein kinase I isoform gamma-1, also known as CSNK1G1, is a member of the protein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Thecasein kinase I family of protein kinases are ... | |||
TMPY-04357 | RSK4 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Ribosomal protein S6 kinase alpha-6, also known as Ribosomal S6 kinase 4, 9 kDa ribosomal protein S6 kinase 6,RSK-4, RSK4 and RPS6KA6, is a protein that belongs to the protein kinase superfamily, AGC Ser/Thr protein kina... | |||
TMPK-00677 | PKA/PRKACA Protein, Canine, Recombinant (His) | Canine | E. coli |
The cAMP-dependent protein kinase PKA is a well-characterized member of the serine-threonine protein AGC kinase family and is the effector kinase of cAMP signaling. As such, PKA is involved in the control of a wide varie... | |||
TMPH-01539 | ILK Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered ... | |||
TMPH-02648 | PKDCC Protein, Mouse, Recombinant (His & Myc) | Mouse | Baculovirus Insect Cells |
Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylati... | |||
TMPJ-01223 | GALNTL1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Putative polypeptide N-acetylgalactosaminyltransferase-like protein 1, also known as Polypeptide GalNAc transferase-like protein 1, Protein-UDP acetylgalactosaminyltransferase-like protein 1, UDP-GalNAc:polypeptide N-ace... | |||
TMPY-04403 | NLK/Nemo Like Kinase Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Nemo-like kinase contains 1 protein kinase domain and belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. It also contains a TQE activation loop motif in which autopho... | |||
TMPJ-00886 | ATF1 Protein, Human, Recombinant (His) | Human | E. coli |
Cyclic AMP-dependent transcription factor ATF-1(ATF1) which contains 1 bZIP (basic-leucine zipper) domain and 1 KID (kinase-inducible) domain, belongs to the bZIP family. It influences cellular physiologic processes by r... | |||
TMPY-04567 | SRPK1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Serine / threonine-protein kinase SRPK1, also known as SFRS protein kinase 1, Serine/arginine-rich protein-specific kinase 1, SR-protein-specific kinase 1 and SRPK1, is a cytoplasm and nucleus protein that belongs to the... | |||
TMPY-04406 | Protein Kinase D2/PRKD2 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Serine/threonine-protein kinase D2, also known as PRKD2 and PKD2, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD2 / PKD2 is ... | |||
TMPY-04373 | CAMKII alpha/CAMK2A Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Ca2+/calmodulin-dependent protein kinase2A (CAMK2A) belongs to the serine/threonine protein kinase family and, together with other 28 different isoforms, belongs to the Ca2+/ calmodulin-dependent protein kinase subfamily... | |||
TMPJ-00314 | ACVR2B Protein, Human, Recombinant (hFc & His) | Human | HEK293 Cells |
Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors... | |||
TMPJ-00315 | ACVR2A Protein, Human, Recombinant (hFc & His) | Human | HEK293 Cells |
Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation fact... | |||
TMPJ-00996 | VHR Protein, Human, Recombinant (His) | Human | E. coli |
Human DUSP3 belongs to the dual specificity protein phosphatase subfamily. DUSPs are a heterogeneous group of protein phosphatases that can dephosphorylate both phosphotyrosine and phosphoserine/phosphothreonine residues... | |||
TMPJ-01074 | PKCE Protein, Human, Recombinant (His) | Human | E. coli |
Protein Kinase C Epsilon type is a member of the serine- and threonine-specific protein kinase family that can be activated by calcium and the second messenger diacylglycerol. Protein Kinase C Epsilon contains these doma... | |||
TMPY-04456 | PKC nu Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Serine/threonine-protein kinase D3, also known as Protein kinase C nu type, Protein kinase EPK2, PRKD3, EPK2 and PRKCN, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr pro... | |||
TMPY-03052 | MFAP5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MFAP5 (Microfibril Associated Protein 5, also known as MAGP2) is a Protein Coding gene. MFAP5 is a component of the elastin-associated microfibrils. It belongs to the MFAP family. As a 25-kD microfibril-associated glycop... | |||
TMPY-02496 | Rad6/UBE2A Protein, Human, Recombinant (His) | Human | E. coli |
Ubiquitin-conjugating enzyme E2 A (also known as HHR6A or UBE2A), encoded by human DNA repair genes HHR6A, belongs to the ubiquitin-conjugating enzymes (E2 enzymes) family and is likely to be involved in postreplication ... | |||
TMPY-02592 | Annexin VI/ANXA6 Protein, Human, Recombinant (His) | Human | E. coli |
Annexin A6, also known as ANXA6 or ANXAⅥ, belongs to a family of Ca2+-dependent membrane and phospholipid binding proteins. Members of this family have been implicated in membrane-related events along exocytotic and endo... | |||
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カタログ番号 | 製品名 | ||
---|---|---|---|
L1400 | MAPK Inhibitor Library | 365 compounds | |
A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases; | |||
L1300 | PI3K-AKT-mTOR Compound Library | 420 compounds | |
A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling; |