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天然化合物

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カタログ番号	製品名	別名	ターゲット
T3422	GRA Ex-25	GRA-Ex-25	Glucagon Receptor
	GRA Ex-25 (GRA-Ex-25) is an inhibitor of glucagon receptor.		Glucagon Receptor
T39933	Bexotegrast	PLN-74809	Integrin
	Bexotegrast (PLN-74809) is an orally active and potent inhibitor of αvβ6 and αvβ1 integrins with antifibrotic effects, inhibits αvβ6 and αvβ1-induced activation of TGF-β, and can be used for the study of idiopathic pulmo...		Integrin
T13721	Homo-PROTAC cereblon degrader 1		Others , PROTACs
	Homo-PROTAC cereblon degrader 1 is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.		Others , PROTACs
T35841	5-Benzyloxygramine		Dopamine Receptor , 5-HT Receptor
	5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1]. 5-benzyloxygramine stabilizes the N-NTD dimers through simultaneous hydrophobic inter...		Dopamine Receptor , 5-HT Receptor
T69753	HDAC6 degrader 9c		HDAC
	HDAC6 degrader 9c is a small molecule histone deacetylase 6 (HDAC6) degrader that can be used to study cancer or other diseases.		HDAC
TQ0292	Grapiprant	AAT-007,RQ-00000007,CJ-023423	Prostaglandin Receptor
	Grapiprant (AAT-007) is a selective EP4 receptor antagonist. Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor (IC50: 35 nM, Ki: 24 nM).		Prostaglandin Receptor
T6024	Zoligratinib	FF284,CH5183284,Debio 1347	FGFR
	Zoligratinib (CH5183284) is a selective and orally available FGFR inhibitor, which is for FGFR1(IC50=9.3 nM), FGFR2(IC50=7.6 nM), FGFR3(IC50=290), and FGFR4(IC50=22 nM), respectively.		FGFR
T31992	Granotapide		CETP
	Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic syndrome, obesity, diabetes mellitus, prediabetes mellitus, an...		CETP
T2239	Raltegravir potassium	MK 0518 potassium salt,Raltegravir potassium salt	HIV Protease , Integrase
	Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.		HIV Protease , Integrase
T3977	Lifitegrast	SHP-606,SAR 1118	Integrin
	Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.		Integrin
T39727	ERα degrader-2		ERK
	ERα degrader-2 is a selective and potent estrogen receptor (SERD) degrader with anticancer activity, inhibits ERα, and has an EC50 value for estrogen receptor degradation of 0.3 nM.ERα degrader-2 can be used for the prev...		ERK
T125901	14-Epiandrographolide
	14-Epiandrographolide is a compound derived from the above-ground parts of Andrographis paniculata that induces cell differentiation and can be used in the study of multiple sclerosis.
T1975	Infigratinib	BGJ-398,NVP-BGJ398	Apoptosis , FGFR
	Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and VEGFR2.		Apoptosis , FGFR
T9236	WSB1 Degrader 1		Others , E1/E2/E3 Enzyme
	WSB1 Degrader 1 is a potent, orally active degrader of WD repeat and SOCS box-containing 1, exhibiting anti-cancer metastatic effects.		Others , E1/E2/E3 Enzyme
T30751	Carotegrast methyl	AJM300	Integrin
	Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.		Integrin
T2329	Dolutegravir sodium	GSK1349572,GSK-1349572A	HIV Protease
	Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.		HIV Protease
T16364	Infigratinib phosphate	NVP-BGJ398 phosphate,BGJ-398 phosphate	FGFR
	Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively).		FGFR
T6098	Cabotegravir	GSK744,GSK-1265744,S/GSK1265744	HIV Protease
	Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM).		HIV Protease
T60742	HIV-1 integrase inhibitor 8		HIV Protease
	HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].		HIV Protease
T39755	Pirmitegravir	STP0404	HIV Protease
	Pirmitegravir (STP0404) is a potent and selective inhibitor of allosteric integrase (ALLINI) targeting the LEDGF/p75 binding site. Pirmitegravir inhibits PBMC. Pirmitegravir inhibits PBMC.Pirmitegravir has significant an...		HIV Protease
T74982	Akt3 degrader 1
	Akt3 Degrader 1 (compound 12l), a selective Akt3 degrader, effectively overcomes Osimertinib-induced resistance in H1975OR NSCLC cells. Besides its role in overcoming drug resistance, it exhibits anti-proliferative prope...
TP1497L	Mast Cell Degranulating Peptide HR-2 acetate	Mast Cell Degranulating Peptide HR-2 acetate(80388-04-1 free base)	Others
	Mast Cell Degranulating Peptide HR-2 acetate from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom.		Others
T11074	Dolutegravir intermediate-1	1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid,1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid	HIV Protease
	Dolutegravir intermediate-1 (1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid) is a new synthetic Dolutegravir intermediate. Dolutegravir is an integrase inhibitor develope...		HIV Protease
T4493	Bictegravir	GS-9883	HIV Protease
	Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM).		HIV Protease
T2332	Elvitegravir	GS-9137,EVG,D06677,JTK-303	HIV Protease
	Elvitegravir (JTK-303) is a Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor. The mechanism of action of elvitegravir is as an HIV Integrase Inhibitor, and Cytochrome P450 2C9 Inducer.		HIV Protease
T1042	Granisetron hydrochloride	BRL 43694A,Granisetron HCl	5-HT Receptor
	Granisetron hydrochloride (Granisetron HCl) is a serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients.		5-HT Receptor
T35340	Bictegravir Sodium	GS-9883 Sodium	HIV Protease
	Bictegravir Sodium (GS-9883 Sodium) is a potent inhibitor of HIV-1 integrase, with an IC50 of 7.5 nM. Bictegravir Sodium exhibits potent and selective anti-HIV activity and low cytotoxicity		HIV Protease
T2239L	Raltegravir	MK-0518	HIV Protease , Integrase
	Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION.		HIV Protease , Integrase
T6300	Degrasyn	WP1130	Apoptosis , JAK , Bcr-Abl , DUB , Autophagy
	Degrasyn (WP1130) (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor, also inhibits Bcr/Abl, which is a JAK2 transducer (without affecting 20S proteasome) and activator of transcri...		Apoptosis , JAK , Bcr-Abl , DUB , Autophagy
T8369	Adagrasib	MRTX849	Ras
	Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib ...		Ras
T40112	PROTAC PD-1/PD-L1 degrader-1	PROTAC PD-1/PD-L1 degrader-1	PROTACs
	PROTAC PD-1/PD-L1 degrader-1, a Cereblon E3 ligand-based compound, is a PD-1/PD-L1 PROTAC that effectively inhibits the interaction between PD-1 and PD-L1 with an IC50 value of 39.2 nM. It successfully restores the suppr...		PROTACs
T6198	Dolutegravir	S/GSK1349572,GSK1349572	HIV Protease
	Dolutegravir (GSK1349572) (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.		HIV Protease
T9013	Autogramin-2	tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate	Autophagy
	Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50...		Autophagy
T4547	Grazoprevir	MK-5172	HCV Protease , SARS-CoV
	Grazoprevir (MK-5172) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.08 nM (gt2a), 0.90 nM (gt3a), 0.01 nM (gt1b), ...		HCV Protease , SARS-CoV
T10413	Autogramin-1		mTOR , Autophagy
	Autogramin-1 potently inhibits autophagy induced by either mTORC1 inhibition (Rapamycin; IC50: 0.44 μM) or starvation (IC50: 0.17 μM).		mTOR , Autophagy
T13722	Homo-PROTAC pVHL30 degrader 1		Others , PROTACs
	Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC.		Others , PROTACs
T8745	PROTAC BRAF-V600E degrader-1	Compound 23	Raf , PROTACs
	PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF.		Raf , PROTACs
TQ0291	Firategrast	SB 683699	Integrin
	Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity...		Integrin
T64284	PROTAC CDK12/13 Degrader-1
	PROTAC CDK12/13 Degrader-1 (7f) is a potent and selective dual degrader of the cell cycle protein-dependent kinases CDK12 (DC50: 2.2 nM) and CDK13 (DC50: 2.1 nM). Breast cancer.
T74852	PROTAC CDK9 degrader-6		CDK
	PROTAC CDK9 degrader-6 is a specific PROTAC targeting CDK9 that mediates its degradation through the proteasome pathway. This compound effectively degrades CDK9 with DC50 values of 0.10 μM and 0.14 μM for the CDK9 42 and...		CDK
T74375	PROTAC ERα Y537S degrader-1
	PROTAC ERα Y537S degrader-1 comprises a ubiquitin E3 ligase binding group, a linker and a protein binding group. PROTAC ERα Y537S degrader-1 is an estrogen receptor-alpha (ERα) Y537S degrader [1] .
T13834	PROTAC BRD4 Degrader-2		Epigenetic Reader Domain
	PROTAC BRD4 Degrader-2 is an efficacious degrader of PROTAC BRD4(BRD4 BD1,IC50 of 14.2 nM).		Epigenetic Reader Domain
T72162	HIV-1 integrase inhibitor 10
	HIV-1 Integrase Inhibitor 10, an orally active allosteric integrase inhibitor (ALLINI), effectively inhibits the NLRepRluc virus's viral outgrowth in MT-2 cells, exhibiting EC50 values of 3-5 nM. This compound is utilize...
T74623	PROTAC EGFR degrader 7
	PROTAC EGFR degrader 7 (compound 13b) is a potent, selective CRBN-recruiting agent targeting EGFR L858R/T790M mutations with a DC50 of 13.2 nM. It effectively inhibits proliferation in NCI–H1975 cells with an IC50 of 46....
T74856	ER degrader 4
	ER degrader 4, a selective and orally active compound, effectively degrades estrogen receptors and exhibits anti-tumor activity [1].
T75020	PROTAC SOS1 degrader-3
	PROTAC SOS1 Degrader-3 is a potent agent specifically designed to target and degrade SOS1 via the ubiquitin-proteasome system [1].
T75029	HEMTAC CDK4/6 degrader 1
	HEMTAC CDK4/6 degrader 1 is a PROTAC connected by ligands for HSP90 and CDK4/6 with a K d value of 35.7 μM. HEMTAC CDK4/6 degrader 1 induces CDK4/6 degradation in B16F10 melanoma cells. HEMTAC CDK4/6 degrader 1 arrests c...
T74125	PROTAC BRD4 Degrader-12
	PROTAC BRD4 Degrader-12 (compound 9c) is a PROTAC that links von Hippel-Lindau and BRD4 ligands. When conjugated with STEAP1 and CLL1 antibodies, this compound effectively degrades BRD4 protein in PC3 prostate cancer cel...
T74353	PROTAC Axl Degrader 1
	PROTAC Axl Degrader 1 is a potent, selective degrader of PROTAC Axl, exhibiting an IC50 of 0.92 µM. It demonstrates in vitro anti-proliferative and anti-migratory activities and induces mehuosis [1].
T74853	PROTAC CDK9 degrader-7
	PROTAC CDK9 degrader-7 is a proteolysis-targeting chimera (PROTAC) specifically designed to target and mediate the degradation of Cyclin-Dependent Kinase 9 (CDK9) through the proteasome pathway [1].

Compounds

GRA Ex-25

T3422

Synonym: GRA-Ex-25

Target: Glucagon Receptor

Homo-PROTAC cereblon degrader 1

T13721

Synonym:

Target: Others, PROTACs

5-Benzyloxygramine

T35841

Synonym:

Target: Dopamine Receptor, 5-HT Receptor

Synonym: AAT-007,RQ-00000007,CJ-023423

Target: Prostaglandin Receptor

Zoligratinib

T6024

Synonym: FF284,CH5183284,Debio 1347

Raltegravir potassium

T2239

Synonym: MK 0518 potassium salt,Raltegravir potassium salt

Target: HIV Protease, Integrase

Lifitegrast

T3977

Synonym: SHP-606,SAR 1118

14-Epiandrographolide

Synonym: BGJ-398,NVP-BGJ398

Target: Apoptosis, FGFR

WSB1 Degrader 1

T9236

Synonym:

Target: Others, E1/E2/E3 Enzyme

Synonym: GSK1349572,GSK-1349572A

Target: HIV Protease

Infigratinib phosphate

T16364

Synonym: NVP-BGJ398 phosphate,BGJ-398 phosphate

Target: FGFR

Cabotegravir

T6098

Synonym: GSK744,GSK-1265744,S/GSK1265744

Target: HIV Protease

HIV-1 integrase inhibitor 8

Mast Cell Degranulating Peptide HR-2 acetate

TP1497L

Synonym: Mast Cell Degranulating Peptide HR-2 acetate(80388-04-1 free base)

Target: Others

Dolutegravir intermediate-1

T11074

Synonym: 1-(2,2-dimethoxyethyl)-5-methoxy-6-methoxycarbonyl-4-oxopyridine-3-carboxylic acid,1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid

Synonym: GS-9137,EVG,D06677,JTK-303

Target: HIV Protease

Granisetron hydrochloride

T1042

Synonym: BRL 43694A,Granisetron HCl

Target: 5-HT Receptor

Bictegravir Sodium

T35340

Synonym: GS-9883 Sodium

Target: HIV Protease, Integrase

Degrasyn

T6300

Synonym: WP1130

Target: Apoptosis, JAK, Bcr-Abl, DUB, Autophagy

PROTAC PD-1/PD-L1 degrader-1

T40112

Synonym: PROTAC PD-1/PD-L1 degrader-1

Target: PROTACs

Dolutegravir

T6198

Synonym: S/GSK1349572,GSK1349572

Target: HIV Protease

Autogramin-2

T9013

Synonym: tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate

Target: HCV Protease, SARS-CoV

Autogramin-1

T10413

Synonym:

Target: mTOR, Autophagy

Homo-PROTAC pVHL30 degrader 1

T13722

Synonym:

Target: Others, PROTACs

PROTAC BRAF-V600E degrader-1

PROTAC CDK12/13 Degrader-1

T64284

Synonym:

Target:

PROTAC CDK9 degrader-6

T74852

Synonym:

Target: CDK

PROTAC ERα Y537S degrader-1

T74375

Synonym:

Target:

PROTAC BRD4 Degrader-2

T13834

Synonym:

Target: Epigenetic Reader Domain

HIV-1 integrase inhibitor 10

T72162

Synonym:

Target:

PROTAC EGFR degrader 7

PROTAC SOS1 degrader-3

T75020

Synonym:

Target:

HEMTAC CDK4/6 degrader 1

T75029

Synonym:

Target:

PROTAC BRD4 Degrader-12

T74125

Synonym:

Target:

PROTAC Axl Degrader 1

T74353

Synonym:

Target:

PROTAC CDK9 degrader-7

T74853

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T5802	Stearyl glycyrrhetinate		Antiviral , Antibacterial
	Stearyl glycyrrhetinate, the stearyl ester of 18-β-glycyrrhetinic acid, has been demonstrated to improve antiviral effects, reduce inflammation and suppress allergies in the pharmaceutical and cosmetic industry.		Antiviral , Antibacterial
TN7026	Acorus gramineus, ext.		Others
	Acorus gramineus, ext is a natural product isolated from Acorus gramineus.		Others
T2738	Dehydroandrographolide		NOS , Influenza Virus
	Dehydroandrographolide is a natural compound extracted from herbal medicine Andrographis paniculata (Burm f) Nees.		NOS , Influenza Virus
TN6705	Graveoline	2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one,Foliosine	Autophagy
	Graveoline (2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one) is an apoptosis and autophagy inducer in skin melanoma cancer cells		Autophagy
TN7091	Isolugrandoside		Others
	Isolugrandoside is from the aerial parts of Digitalis davisiana Heywood.		Others
T3884	Neoandrographolide	Neoandrographiside	NOS , COX
	Neoandrographolide (Neoandrographiside) has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.Neoandrographolide has anti-inflammatory effect, might result from inhibition of iN...		NOS , COX
TJS1748	Methyl protogracillin		Antifection
	Methyl protogracillin is a natural product from Dioscorea collettii var. hypoglauca with anti-cancer activity.		Antifection
T6520	Grape Seed Extract	Grape Seed P.E.	Apoptosis , Others
	Grape Seed Extract (Grape Seed P.E.) is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites (BIOFLAVONOIDS and polyphenols) credited with important medicinal properties.		Apoptosis , Others
T1130	Gramicidin	Gramicidinum,Gramicidine,Gramicidina	MRP , Antibacterial , Antibiotic
	A group of peptide antibiotics from BACILLUS brevis. Gramicidin (Gramicidine) C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is one of the two principal components of TYROTH...		MRP , Antibacterial , Antibiotic
T9218	Andrograpanin	19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE	p38 MAPK
	Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.		p38 MAPK
TQ0218	Deoxyandrographolide	14-deoxyandrographolide	IL Receptor , TNF
			IL Receptor , TNF
T8288	14-Deoxyandrographolide		Apoptosis , Others
	14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.		Apoptosis , Others
TQ0185	14-Deoxy-11,12-didehydroandrographolide	AP10,14-dehydro Andrographolide	NF-κB
	14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.		NF-κB
T3774	Gracillin		cell cycle arrest
	Gracillin can induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells, and has the potential to be developed as an antitumor agent. Gracillin can be selected as lead compounds for the development of new d...		cell cycle arrest
T3667	Kalii Dehydrographolidi Succinas	Ddhads,Dehydroandrographolide Succinate Potasium Salt	Others
	Kalii Dehydrographolidi Succinas (Dehydroandrographolide Succinate Potasium Salt) is a natural compound with anti-virus infection activity.		Others
T2S0257	Dehydroandrographolide succinate		Others , Influenza Virus
	Dehydroandrographolide Succinate is a traditional Chinese medicine used in the treatment of pneumonia, respiratory tract infection.		Others , Influenza Virus
T2898	Andrographolide	Andrographis	SARS-CoV , Influenza Virus , NF-κB , Autophagy
	Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential antineoplastic.		SARS-CoV , Influenza Virus , NF-κB , Autophagy
TN1038	Galgravin		Apoptosis
	Galgravin has anti-inflammatory, and neuroprotective effects, it can promote neuronal survival and neurite outgrowth, protect hippocampal neurons against amyloid beta peptide (Abeta25-35)-induced cytotoxicity, and protec...		Apoptosis
T2S1749	Protogracillin		Others
	Protogracillin may have inhibitions on platelet aggregation (PAG) and thrombosis.		Others
T8898	Granilin	Graniline	Others , Antibacterial , Antifungal
	Granilin (Graniline)e is a natural product.		Others , Antibacterial , Antifungal
TN7092	Lugrandoside		Others
	Lugrandoside is a novel phenylpropanoid glycoside, lugrandoside, has been isolated from the caulinary leaves of Digitalis Lutea L. and Difitalis Grandiflora Miller.		Others
T6519	Gramine	NSC 16892,Donaxine	Adiponectin receptor , Reverse Transcriptase , Adrenergic Receptor
	Gramine (Donaxine), a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1, respectively. Gramine is als...
T2S0250	Pseudoprotogracillin		Others
	Pseudoprotogracillin is a steroidal saponin extracted from Dioscoreae.		Others
TN4078	Fragransin A2		Others
	Fragransin A2 is a natural product of Myristica, Myristicaceae. The catalog number is TN4078 and the CAS number is 112652-46-7. Fragransin A2 can be used as a reference standard.		Others
TN5710	Integracin A
	Integracin A is a natural product for research related to life sciences. The catalog number is TN5710 and the CAS number is 224186-03-2.
TN4165	Grayanotoxin I		Others
	Grayanotoxin I is a natural product for research related to life sciences. The catalog number is TN4165 and the CAS number is 4720-09-6.		Others
T72580	Isoandrographolide
	Isoandrographolide, a compound known for its cell differentiation-inducing and hepatoprotective effects, also inhibits NLRP3 inflammasome activation and mitigates silicosis in mice.
TN5430	Pomegralignan
	Pomegralignan is a natural product for research related to life sciences. The catalog number is TN5430 and the CAS number is 1562492-32-3.
T20217	Grandiflorenic acid
	Grandiflorenic acid can reproduce the uterine responses induced by aqueous extract of zoapatle leaves. It is suggested that grandiflorenic acid may have an antifertility effect.
T41042	Gramicidin C
	Gramicidin C, a naturally occurring polypeptide antibiotic, is isolated from B. brevis var. G.B.
T82562	Dide-O-methylgrandisin
	Dide-O-methylgrandisin, a neolignan of the diaryltetrahydrofuran class, is referenced as compound [1].
TN3411	Andrographidine C		Others
	Andrographidine C is a natural product of Andrographis, Acanthaceae. The catalog number is TN3411 and the CAS number is 113963-39-6. Andrographidine C can be used as a reference standard.		Others
T40924	Tellimagrandin II	Eugeniin
	Tellimagrandin II (Eugeniin) is the initial intermediate in the 4 C 1 -glucose derived series of ellagitannins. Additionally, it possesses the ability to inhibit antibiotic resistance exhibited by drug-resistant Staphylo...
T31993	Grayanotoxin II	G-II,Deacetylanhydroandromedotoxin,delta(sup 10 (18))-Andromedenol
	Grayanotoxins are a group of closely related neurotoxins named after Leucothoe grayana. Extract from leaves of Ericaceae.
TN5586	14-Deoxy-12-hydroxyandrographolide
	14-Deoxy-12-hydroxyandrographolide is a natural product of Andrographis, Acanthaceae. The catalog number is TN5586 and the CAS number is 219721-33-2. 14-Deoxy-12-hydroxyandrographolide can be used as a reference standard...
TN3605	Casegravol		Others
	Casegravol is a new monomeric coumarin isolated from the bark of Casearia graveolens Dalz with antiproliferative activity and can be used in the study of gastric adenocarcinoma and uterine cancer.		Others
TN4164	Grandifloroside		TNF
	Grandifloroside shows good antioxidative and potent anti-inflammatory activities, it also exhibits potent inhibitory activity against TNF-α and 5α-reductase, suggests that it might be developed as a source of potent anti...		TNF
TN3412	Andrographiside		Others
	Andrographiside shows protective effects on hepatotoxicity induced in mice by carbon tetrachloride or tert-butylhydroperoxide (tBHP) intoxication, the effects could be due to its glucoside groups which may act as strong ...		Others
TN1713	Graveobioside A		Others
	Graveobioside A can be used in hyperuricemia and gout-resistant drugs or health foods.		Others
T13796	Nigranoic acid		HIV Protease
	Nigranoic acid is a natural product,and inhibits HIV-1 reverse transcriptase.		HIV Protease
T36439	Gramicidin A		Antibacterial , HIF , Parasite
	Gramicidin A is a peptide antibiotic isolated from B. brevis.Gramicidin A is a highly hydrophobic channel-forming ion carrier that forms monovalent cation-permeable channels in artificial membranes.Gramicidin A induces t...		Antibacterial , HIF , Parasite
TN2602	12-Oxograndiflorenic acid		Others
	12-Oxograndiflorenic acid is a natural product that can be extracted from Anemone and Porphyra and is cytotoxic to some cells.		Others
T75677	Protoneogracillin
	Protoneogracillin, a furostanol glycoside, demonstrates anti-fungal activity against the plant pathogenic fungus P.oryzae (MMDC=94.0 μM) and exhibits cytotoxic activity against K562 cancer cells (IC 50 =6.6 μM) [1] [2].
T13582	Bisandrographolide C		Others
	Bisandrographolide C is identified from Andrographis paniculata. Bisandrographolide C activates TRPV1 and TRPV3 channels (Kds: 289 and 341 μM) and protects cardiomyocytes from hypoxia-reoxygenation injury.		Others
T83441	17-Hydroxygracillin
	17-Hydroxygracillin, a saponin [1], exhibits various biological activities.
T82262	Grandivine A
	Grandivine A, a steroid alkaloid, has been isolated from Veratrum grandiflorum [1].
TN2623	14-Deoxy-17-hydroxyandrographolide		Antifection
	14-Deoxy-17-hydroxyandrographolide is a natural product of Andrographis, Acanthaceae. The catalog number is TN2623 and the CAS number is 869384-82-7. 14-Deoxy-17-hydroxyandrographolide can be used as a reference standard...		Antifection
TN2291	Uvarigranol B		Others
	Uvarigranol B is a natural product		Others
TN6599	Andrographidine A
	Andrographidine A is a natural product for research related to life sciences. The catalog number is TN6599 and the CAS number is 113963-37-4.
TN5387	Grasshopper ketone		ERK , p38 MAPK , NO Synthase , JNK
	Grasshopper ketone, isolated from the brown alga Sargassum, is a potent inhibitor of LPS-induced NO production in RAW 264.7 cells and induces anti-inflammatory effects by inhibiting MAPK (ERK, JNK and p38) and NF-κB p65 ...		ERK , p38 MAPK , NO Synthase , JNK
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天然物製品

Stearyl glycyrrhetinate

T5802

Synonym:

Target: Antiviral, Antibacterial

Acorus gramineus, ext.

TN7026

Synonym:

Target: Others

Dehydroandrographolide

T2738

Synonym:

Target: NOS, Influenza Virus

Graveoline

TN6705

Synonym: 2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one,Foliosine

Synonym: Neoandrographiside

Target: NOS, COX

Methyl protogracillin

Synonym: Grape Seed P.E.

Target: Apoptosis, Others

Gramicidin

T1130

Synonym: Gramicidinum,Gramicidine,Gramicidina

Target: MRP, Antibacterial, Antibiotic

Andrograpanin

T9218

Synonym: 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE

Target: p38 MAPK

Deoxyandrographolide

TQ0218

Synonym: 14-deoxyandrographolide

Target: IL Receptor, TNF

14-Deoxyandrographolide

T8288

Synonym:

Target: Apoptosis, Others

14-Deoxy-11,12-didehydroandrographolide

TQ0185

Synonym: AP10,14-dehydro Andrographolide

Target: cell cycle arrest

Kalii Dehydrographolidi Succinas

T3667

Synonym: Ddhads,Dehydroandrographolide Succinate Potasium Salt

Target: Others

Dehydroandrographolide succinate

T2S0257

Synonym:

Target: Others, Influenza Virus

Andrographolide

T2898

Synonym: Andrographis

Target: SARS-CoV, Influenza Virus, NF-κB, Autophagy

Target: Others, Antibacterial, Antifungal

Synonym: NSC 16892,Donaxine

Target: Adiponectin receptor, Reverse Transcriptase, Adrenergic Receptor

Grandiflorenic acid

Dide-O-methylgrandisin

Synonym: G-II,Deacetylanhydroandromedotoxin,delta(sup 10 (18))-Andromedenol

Target:

14-Deoxy-12-hydroxyandrographolide

Target: Antibacterial, HIF, Parasite

12-Oxograndiflorenic acid

14-Deoxy-17-hydroxyandrographolide

Target: ERK, p38 MAPK, NO Synthase, JNK

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-05159	Granzyme A/GZMA Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Granzyme A/GZMA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.5 kDa and the accession number is P12544-1.
TMPY-00817	Granzyme B/GZMB Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ...
TMPY-00978	Progranulin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1.
TMPH-03368	SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May also play a role in angiogenesis. Promotes...
TMPH-03632	GRA1 Protein, Toxoplasma gondii, Recombinant (His)	Toxoplasma gondii	E. coli
	N/A. GRA1 Protein, Toxoplasma gondii, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.9 kDa and the accession number is P13403.
TMPH-00070	Major allergen Api g 1, isoallergen 2 Protein, Apium graveolens, Recombinant (His)	Apium graveolens	E. coli
	Major allergen Api g 1, isoallergen 2 Protein, Apium graveolens, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.1 kDa and the accession number is P92918...
TMPH-01412	Granzyme B Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Granzyme B Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.0 kDa and the accession number is P10144.
TMPH-03633	GRA2 Protein, Toxoplasma gondii, Recombinant (His & Myc)	Toxoplasma gondii	E. coli
	Major granular component involved in excreted-secreted antigen (ESA) immunity. Possibly acts in conjunction with GRA1. GRA2 Protein, Toxoplasma gondii, Recombinant (His & Myc) is expressed in E. coli expression system wi...
TMPH-03634	GRA3 Protein, Toxoplasma gondii, Recombinant (His)	Toxoplasma gondii	E. coli
	Direct host-parasite interaction occurs at the cytoplasmic faces of the parasitophorous vacuole membrane (PVM) and the host endoplasmic reticulum (ER) membrane via GRA3 and host CAMLG association. Direct insertion of GRA...
TMPJ-00925	Grancalcin Protein, Human, Recombinant	Human	E. coli
	Grancalcin (GCA) is a cytoplasmic granule membrane protein that contains 4 EF-hand domains. GCA is calcium-binding protein and particularly abundant in human neutrophils. GCA is highly expressed in bone marrow, and it ca...
TMPK-00673	SG3/Secretogranin 3 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regu...
TMPH-02068	Secretogranin-1 Protein, Human, Recombinant (GST & His)	Human	E. coli
	Secretogranin-1 Protein, Human, Recombinant (GST & His) is expressed in E. coli.
TMPH-02688	Granzyme C/GZMC Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	This enzyme is probably necessary for target cell lysis in cell-mediated immune responses. Granzyme C/GZMC Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. Th...
TMPY-00818	Granzyme H/GZMH Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. A total of eight granzymes...
TMPY-01435	Progranulin Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Progranulin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63 kDa and the accession number is P28798.
TMPH-03159	DODA Protein, Portulaca grandiflora, Recombinant (His & Myc & SUMO)	Portulaca grandiflora	E. coli
	Opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. DODA Protein, Portulaca grandiflora, Recombinant (...
TMPY-03994	SG3/Secretogranin 3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SG3/Secretogranin 3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.4 kDa and the accession number is AAH14539.1.
TMPH-00069	Major allergen Api g 1, isoallergen 1 Protein, Apium graveolens, Recombinant (His & SUMO)	Apium graveolens	E. coli
	Major allergen Api g 1, isoallergen 1 Protein, Apium graveolens, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 32.3 kDa and the accession numb...
TMPJ-00770	Granzyme B/GZMB Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an...
TMPK-01122	SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His)	Human	HEK293 Cells
	Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regu...
TMPJ-00832	Granzyme D/GZMD Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, b...
TMPH-02069	Secretogranin-2 Protein, Human, Recombinant (GST & His)	Human	E. coli
	Secretogranin-2 Protein, Human, Recombinant (GST & His) is expressed in E. coli.
TMPH-02689	Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli with N-terminal 10xHis tag and C-terminal Myc tag. The predicted molecular weight is 33.9 kDa. Accession number: O35205
TMPH-02687	Granzyme A/GZMA Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or ...
TMPY-04675	SG3/Secretogranin 3, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	SG3/Secretogranin 3, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.4 kDa and the accession number is P47867-1.
TMPY-06547	Granulysin Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Granulysin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.12 kDa and the accession number is P22749-1.
TMPH-03635	GRA6 Protein, Toxoplasma gondii, Recombinant (GST)	TOV-Toxoplasma gondii	E. coli
	Major granular component involved in excreted-secreted antigen (ESA) immunity. May have a structural role in the membranous network of the parasitophorous vacuole (PV). GRA6 Protein, Toxoplasma gondii, Recombinant (GST) ...
TMPH-00755	Integrase Protein, Escherichia phage lambda, Recombinant (His)	Escherichia phage lambda	E. coli
	Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. Int...
TMPY-06567	Granzyme K/GZMK Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Granzyme K/GZMK Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.56 kDa and the accession number is NP_002095.1.
TMPH-02452	Measles virus (MeV) (strain Leningrad-16) Fusion glycoprotein F0 (Avi & His)	MeV	E. coli
	Measles virus (MeV) (strain Leningrad-16) Fusion glycoprotein F0 (Avi & His) is expressed in E. coli expression system with N-10xHis and C-Avi tag. The predicted molecular weight is 61.8 kDa and the accession number is P...
TMPY-03968	Secretogranin II Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Kit ligand, also known as Hematopoietic growth factor KL, Mast cell growth factor, Steel factor, Stem cell factor, c-Kit ligand, Kitlg and KITL, is a single-pass type I membrane protein that belongs to the SCF family. KI...

Granzyme A/GZMA Protein, Human, Recombinant (His)

TMPY-05159

Species: Human

Expression System: HEK293 Cells

Granzyme B/GZMB Protein, Human, Recombinant (His)

TMPY-00817

Species: Human

Expression System: HEK293 Cells

Progranulin Protein, Human, Recombinant (His)

TMPY-00978

Species: Human

Expression System: HEK293 Cells

SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc)

TMPH-03368

Species: Rat

Expression System: E. coli

GRA1 Protein, Toxoplasma gondii, Recombinant (His)

TMPH-03632

Species: Toxoplasma gondii

Expression System: E. coli

Major allergen Api g 1, isoallergen 2 Protein, Apium graveolens, Recombinant (His)

TMPH-00070

Species: Apium graveolens

Expression System: E. coli

Granzyme B Protein, Human, Recombinant (E. coli, His)

TMPH-01412

Species: Human

Expression System: E. coli

GRA2 Protein, Toxoplasma gondii, Recombinant (His & Myc)

TMPH-03633

Species: Toxoplasma gondii

Expression System: E. coli

GRA3 Protein, Toxoplasma gondii, Recombinant (His)

TMPH-03634

Species: Toxoplasma gondii

Expression System: E. coli

Grancalcin Protein, Human, Recombinant

TMPJ-00925

Species: Human

Expression System: E. coli

SG3/Secretogranin 3 Protein, Cynomolgus, Recombinant (His)

TMPK-00673

Species: Cynomolgus

Expression System: HEK293 Cells

Secretogranin-1 Protein, Human, Recombinant (GST & His)

TMPH-02068

Species: Human

Expression System: E. coli

Granzyme C/GZMC Protein, Mouse, Recombinant (His & Myc)

TMPH-02688

Species: Mouse

Expression System: E. coli

Granzyme H/GZMH Protein, Human, Recombinant (His)

TMPY-00818

Species: Human

Expression System: HEK293 Cells

Progranulin Protein, Mouse, Recombinant (His)

TMPY-01435

Species: Mouse

Expression System: HEK293 Cells

DODA Protein, Portulaca grandiflora, Recombinant (His & Myc & SUMO)

TMPH-03159

Species: Portulaca grandiflora

Expression System: E. coli

SG3/Secretogranin 3 Protein, Human, Recombinant (His)

TMPY-03994

Species: Human

Expression System: HEK293 Cells

Major allergen Api g 1, isoallergen 1 Protein, Apium graveolens, Recombinant (His & SUMO)

TMPH-00069

Species: Apium graveolens

Expression System: E. coli

Granzyme B/GZMB Protein, Mouse, Recombinant (His)

TMPJ-00770

Species: Mouse

Expression System: HEK293 Cells

SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His)

TMPK-01122

Species: Human

Expression System: HEK293 Cells

Granzyme D/GZMD Protein, Mouse, Recombinant (His)

TMPJ-00832

Species: Mouse

Expression System: HEK293 Cells

Secretogranin-2 Protein, Human, Recombinant (GST & His)

TMPH-02069

Species: Human

Expression System: E. coli

Granzyme K/GZMK Protein, Mouse, Recombinant (His & Myc)

TMPH-02689

Species: Mouse

Expression System: E. coli

Granzyme A/GZMA Protein, Mouse, Recombinant (His)

TMPH-02687

Species: Mouse

Expression System: E. coli

SG3/Secretogranin 3, Mouse, Recombinant (His)

TMPY-04675

Species: Mouse

Expression System: HEK293 Cells

Granulysin Protein, Human, Recombinant (hFc)

TMPY-06547

Species: Human

Expression System: HEK293 Cells

GRA6 Protein, Toxoplasma gondii, Recombinant (GST)

TMPH-03635

Species: TOV-Toxoplasma gondii

Expression System: E. coli

Integrase Protein, Escherichia phage lambda, Recombinant (His)

TMPH-00755

Species: Escherichia phage lambda

Expression System: E. coli

Granzyme K/GZMK Protein, Human, Recombinant (His)

TMPY-06567

Species: Human

Expression System: HEK293 Cells

Measles virus (MeV) (strain Leningrad-16) Fusion glycoprotein F0 (Avi & His)

TMPH-02452

Species: MeV

Expression System: E. coli

Secretogranin II Protein, Human, Recombinant (His)

TMPY-03968

Species: Human

Expression System: HEK293 Cells

カタログ番号	製品名
L8110	Reprogramming Compound Library		1813 compounds
	A unique collection of 1813 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening.

ライブラリー

Reprogramming Compound Library

L8110

Compounds: 1813