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カタログ番号 | 製品名 | 別名 | ターゲット |
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T2355 | CFTR(inh)-172 | CFTRinh 172,CFTR Inhibitor-172,CFTRinh-172,CFTRinh172 | CFTR , Autophagy |
CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor. | |||
T35883 | RNF5 inhibitor inh-02 | RNF5 inhibitor inh-02 | |
RNF5 inhibitor inh-02, a potent E3 ubiquitin ligase RNF5/RMA1 inhibitor, demonstrates significant efficacy in rescuing F508del-CFTR with an EC50 of 2.2 uM in bronchial epithelial cells homozygous for the F508del mutation... | |||
T24846 | T16A(inh)-C01 | T16A(inh) C01 | |
T16A(inh)-C01 is the Ca(2+)-activated Cl(-) Channel, Ano1 class C inhibitor. | |||
T24847 | T16A(inh)-D01 | T16A(inh) D01,T16Ainh-D01,T16AinhD01,T16A(inh)D01,T16Ainh D01 | |
T16A(inh)-D01 is the Ca(2+)-activated Cl(-) Channel, Ano1 class D inhibitor. | |||
T24845 | T16A(inh)-B01 | T16Ainh-B01,T16A(inh)B01,T16AinhB01,T16Ainh B01 | |
T16A(inh)-B01 is the Ca(2+)-activated Cl(-) Channel, Ano1 class B inhibitor. | |||
T71615 | INH-13 | ||
INH-13 is a Aurora inhibitor. | |||
T0972 | Isoniazid | INH,Isonicotinic acid hydrazide,Isonicotinic hydrazide | Mitophagy , Dehydrogenase , CAT , Antibacterial , Autophagy |
Isoniazid (Isonicotinic hydrazide) is an antibacterial agent used primarily as a tuberculostatic. | |||
T6180 | INH6 | Apoptosis , Microtubule Associated | |
INH6, an effective Hec1 inhibitor, selectively disrupts the Hec1/Nek2 interaction and induces chromosome mis-alignment. | |||
T11657 | INH154 | Others | |
INH154 is a highly potent inhibitor for Nek2 and Hec1 binding (INH), with IC50s of 120 nM and 200 nM for INH in MB468 and Hela cells. | |||
T2502 | INH1 | IBT13131 | Apoptosis , Microtubule Associated |
INH1 (IBT13131) is a cell-permeable Hec1 inhibitor that specifically disrupts the Hec1/Nek2 interaction. | |||
T5209 | INH14 | IκB/IKK | |
INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ). | |||
T29081 | UTA1inh-C1 | UTA1-inh-C1,UTA1(inh)-C1 | |
UTA1inh-C1 is a novel inhibitor of kidney urea transporter UT-A1. | |||
T29080 | UTA1inh-B1 | UTA1(inh)-B1,UTA1inhB1 | |
UTA1inh-B1 is a novel inhibitor of kidney urea transporter UT-A1. | |||
T29079 | UTA1inh-A1 | UTA1-inh-A1,UTA1(inh)-A1 | |
UTA1inh-A1 is a novel inhibitor of kidney urea transporter UT-A1. | |||
T29082 | UTA1inh-D1 | UTA1-inh-D1,UTA1inh D1,UTA1(inh)-D1,UTA1inhD1 | |
UTA1inh-D1 is a novel inhibitor of kidney urea transporter UT-A1 . | |||
T81024 | Tefibazumab | INH-H 2002 | |
Tefibazumab, a humanized IgG1κ monoclonal antibody, targets and binds to clumping factor A, an adhesion protein expressed on the surface of Staphylococcus aureus, and is under investigation for the treatment of serious S... | |||
T71613 | MK-8712 | ||
MK-8712 is a monobactam beta-lactamase inhibitor. | |||
T2602 | Barasertib-HQPA | 1H-Pyrazole-3-acetamide,Barasertib,AZD1152-HQPA,AZD2811,AZD1152-HQPA|AZD2811 | Apoptosis , Aurora Kinase |
Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A. | |||
T22831 | Protein kinase inhibitor H-7 dihydrochloride | H-7 dihydrochloride | PKC |
Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor. Protein kinase inhibitor H-7 dihydrochloride (100 μM) significantly inhibits TPA (skin tumor promoter, 12-O-... | |||
T22195 | CBFβ Inhibitor | 5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine | DNA/RNA Synthesis |
CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1. | |||
T1804 | HPGDS inhibitor 1 | HPGDS-inhibitor-1 | PGE Synthase |
HPGDS inhibitor 1 is a novel and selective inhibitor for Hematopoietic Prostaglandin D Synthase (HPGDS) with an IC50 Value of 0.7 nM. | |||
T6335 | Tie2 kinase inhibitor 1 | Tie2 kinase inhibitor | Tie-2 |
Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor), an optimized compound of SB-203580, is selective to Tie2 with IC50 of 0.25 μM, which is 200-fold more effective than p38. | |||
T3593 | Src Inhibitor 1 | Src Kinase Inhibitor 1,Src-l1 | Src |
Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor. | |||
TP1015 | NFAT Inhibitor | VIVIT peptide | Others |
NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT. | |||
T6409 | ALK kinase inhibitor-1 | SAR348830 | Others |
SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase. | |||
T15654 | Ketohexokinase inhibitor 1 | PF-06835919 | Others |
Ketohexokinase inhibitor 1 is a ketohexokinase inhibitor (IC50s: 8.4 nM and 66 nM for KHK-C and KHK-A, respectively). | |||
TP2310 | Autocamtide-2-related inhibitory peptide | CaMK , Autophagy | |
Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM. | |||
T83627 | Pim-1 kinase inhibitor 8 | Pim , PKC | |
Pim-1 kinase inhibitor 8 is a potent Pim-1 kinase inhibitor with anticancer activity and can effectively inhibit cell migration.Pim-1 kinase inhibitor 8 is cytotoxic to MCF-7 and HepG2 cells, and is a candidate compound ... | |||
T50103 | NFAT Inhibitor-2 | Others | |
NFAT Inhibitor-2 is a compound used as a molecular building block. | |||
T5831 | Selective PI3Kδ Inhibitor 1 | PI3K | |
Selective PI3Kδ Inhibitor 1 is a PI3Kδ Inhibitor( IC50 = 0.9 nM). | |||
T22043 | BCATc Inhibitor 2 | Others | |
BCATc Inhibitor 2 exhibited an IC50 of 0.8 microM in the hBCATc assays; it is an active and selective inhibitor. BCATc Inhibitor 2 also blocked calcium influx into neuronal cells following inhibition of glutamate uptake,... | |||
T9044 | SORT-PGRN interaction inhibitor 1 | Neurotensin Receptor | |
SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM). | |||
T9631 | IRAK-4 protein kinase inhibitor 2 | IRAK | |
IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM). | |||
T60742 | HIV-1 integrase inhibitor 8 | HIV Protease | |
HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1]. | |||
T6015 | Cathepsin Inhibitor 1 | Cysteine Protease | |
Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively. | |||
T9725 | GSK-3β inhibitor 10 | Others | |
GSK-3β inhibitor 10 has skin-whitening, anti-oxidizing and PPAR activities. | |||
T67899 | Topoisomerase II inhibitor 13 | Topoisomerase | |
Topoisomerase II inhibitor 13 inhibits topoisomerase II (Topo II) that shows strong anti-proliferation activity against HL-60/MX2 cancer cells derived from HL-60 against Topo II toxicity. | |||
T9939 | JMJD6 inhibitor WL12 | 2H-1-Benzopyran-2-one, 3-(3H-imidazo[4,5-c]pyridin-2-yl)-6-methyl-,ZINC6733033 | Others |
JMJD6 inhibitor WL12 (ZINC6733033) is a first-in-class JMJD6 inhibitor and was shown to be able to suppress JMJD6-dependent cancer cell proliferation including cervical and liver cancer cells, providing a small-molecule ... | |||
T2705 | Mutant EGFR inhibitor | EGFR | |
Mutant EGFR inhibitor is a selective and potent Mutated EGFR inhibitor, inhibits L858R activating mutant, the Exonl9 deletion activating mutant and the T790M resistance mutant. | |||
T37048 | MMP-3 Inhibitor | MMP | |
MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity. | |||
T13059 | T16Ainh-A01 | Chloride channel | |
T16Ainh-A01 is a potent inhibitor of TMEM16A Chloride channel, inhibiting TMEM16A-mediated chloride currents (IC50 of 1 µM),and functions as a calcium-activated chloride channel (CaCC). | |||
T67767 | HIF-1 inhibitor-4 | HIF-1 inhibitor-4 | HIF |
HIF-1 inhibitor-4 (HIF-1 inhibitor-4) is a HIF-1 inhibitor with IC50 of 560 nM. HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level. | |||
T60358 | SEH inhibitor-7 | Epoxide Hydrolase | |
sEH inhibitor-7 is a soluble epoxide hydrolase (sEH) inhibitor that inhibits sEH in human and mouse with IC 50 s of 6.2 μM and 0.15 μM, respectively. sEH inhibitor-7 is associated with anti-inflammatory active molecules. | |||
T9393 | (E)-Akt inhibitor-IV | (E)-AKTIV,CS-1992 | Akt |
(E)-Akt inhibitor-IV ((E)-AKTIV) ((E)-AKTIV) is an inhibitor of PI3K-Akt. | |||
T9713 | δ-secretase inhibitor 11 | Beta Amyloid , Caspase | |
δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment. | |||
T61318 | BRD4 Inhibitor-20 | Epigenetic Reader Domain | |
BRD4 Inhibitor-20 is a potent bromodomain protein 4 (BRD4) inhibitor with oral activity. BRD4 Inhibitor-20 has antiproliferative activity in cancer cell lines and is used in studies of various cancers, such as colon canc... | |||
T11190 | EMT inhibitor-1 | Wnt/beta-catenin | |
EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity. | |||
T11279 | FGFR1/DDR2 inhibitor 1 | Discoidin Domain Receptor (DDR) , FGFR , Others | |
FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively. | |||
T21512 | MMP-2/MMP-9 Inhibitor I | MMP | |
MMP-2/MMP-9-IN-1 is a potent, highly selective and orally bioavailable inhibitor of type IV collagenases (MMP-9 and MMP-2) with an IC50 of 0.24 and 0.3 1 μM for MMP-9 and MMP-2, respectively. activity, which can be used ... | |||
T17192 | Ubiquitin Isopeptidase Inhibitor I, G5 | NSC144303 | Apoptosis |
Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively). |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T35782 | Swinholide A | MK-7684 | Antifungal |
Swinholide A is a polyketone compound that can be extracted from sponges and binds to actin to dimerize actin with Kd of about 50 nM. Swinholide A is a cytotoxin that stabilizes actin dimers and severs actin filaments. S... | |||
TN1848 | Kuwanon E | AChR | |
Kuwanon E inhibited cholinesterase enzyme in a dose-dependent manner with K i values ranging between 3.1 and 37.5 μM and between 1.7 and 19.1 μM against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzyme... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPJ-01064 | Serpin G1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
SERPIN G1 is a member of the serpin family, The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. SERPIN G1 is involved in the inhibition of the complement sy... | |||
TMPJ-00502 | Serpin G1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. Serpin G1 is a serine protease inhibitor protein... | |||
TMPY-04815 | C1 inhibitor Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
C1 inhibitor Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.7 kDa and the accession number is A6HMR4. | |||
TMPH-01530 | INHBA Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary... | |||
TMPH-00520 | Host-nuclease inhibitor protein gam Protein, Enterobacteria phage lambda, Recombinant (His & Myc) | Escherichia phage lambda | E. coli |
Binds to host RecBCD nuclease and inhibits it thereby protecting the viral DNA against recBCD mediated degradation. | |||
TMPJ-01015 | INHBC Protein, Human, Recombinant (C-His) | Human | HEK293 Cells |
Inhibin beta C chain, also known as activin beta-C chain and INHBC, belongs to the TGF-beta family. INHBC forms a homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disul... | |||
TMPH-03528 | Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS47), Recombinant (His & Myc) | Staphylococcus aureus | E. coli |
Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leu... | |||
TMPH-00395 | Autolysin Protein, Chlamydomonas reinhardtii, Recombinant (His & SUMO) | Chlamydomonas reinhardtii | E. coli |
Mediates digestion of the cell walls of the 2 mating type gametes during mating as a necessary prelude to cell fusion. This enzyme acts specifically on the framework proteins (inner wall) of the cell wall, cleaving sever... | |||
TMPH-00272 | Inhibin alpha chain/INHA Protein, Bovine, Recombinant (His & SUMO) | Bovine | E. coli |
Inhibin alpha chain/INHA Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.6 kDa and the accession number is P07994. | |||
TMPY-01190 | INHBB Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two ... | |||
TMPY-01183 | C1 inhibitor Protein, Human, Recombinant (His) | Human | HEK293 Cells |
C1 inhibitor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.3 kDa and the accession number is E9KL26. | |||
TMPH-02787 | Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (His) is expressed in Yeast. | |||
TMPH-02788 | Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli. | |||
TMPH-03529 | Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Recombinant (His) | Staphylococcus aureus | P. pastoris (Yeast) |
Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leu... | |||
TMPJ-01016 | INHBC Protein, Human, Recombinant (N-His) | Human | E. coli |
Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation,... | |||
TMPH-00554 | Trypsin inhibitor DE-3 Protein, Erythrina caffra, Recombinant (His) | Erythrina caffra | P. pastoris (Yeast) |
Inhibition of trypsin. | |||
TMPY-05029 | INHBE Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
INHBE (Inhibin Subunit Beta E) is a Protein Coding gene. This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to gen... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L9410 | Covalent Inhibitor Library | 1920 compounds | |
A unique collection of 1920 covalent Inhibitors and other molecules with common warheads like chloroacetyl,2-Chloropropionyl,Acryloyl,sulfonyl fluoride, alkyne,acrylamide, ketocarbonyl,disulfide bond, etc. | |||
L2200 | Tyrosine Kinase Inhibitor Library | 1016 compounds | |
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases; | |||
L2000 | Inhibitor Library | 8328 compounds | |
A unique collection of 8328 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L9400 | PPI Inhibitor Library | 485 compounds | |
A unique collection of 485 PPI-related compounds for drug screening; | |||
L9100 | Phosphatase Inhibitor Library | 79 compounds | |
A collection of 79 phosphatase inhibitors with known activity; | |||
L1100 | Protease Inhibitor Library | 343 compounds | |
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening; | |||
L2300 | Ion Channel Inhibitor Library | 931 compounds | |
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery; | |||
DO2200 | Covalent inhibitors Library | 12000 compounds | |
L1400 | MAPK Inhibitor Library | 365 compounds | |
A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases; | |||
L1610 | FDA-Approved Kinase Inhibitor Library | 263 compounds | |
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening. | |||
L3600 | Cytokine Inhibitor Library | 604 compounds | |
A unique collection of 604 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery; | |||
L2010 | Highly Selective Inhibitor Library | 575 compounds | |
L1600 | Kinase Inhibitor Library | 2720 compounds | |
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases; | |||
L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; |