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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T9614 | MERS-CoV-IN-1 | SARS-CoV | |
MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus.It is useful as a pharmaceutical composition for preventing coronavirus-induced diseases (MERS-CoV and SARS). | |||
T9109 | SSAA09E2 | RAAS , SARS-CoV | |
SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2 (ACE2). | |||
T8419 | XP-59 | SARS-CoV | |
XP-59 is a potent the SARS-CoV Mpro inhibitor(Ki : 0.1 μM). | |||
T9351 | Nirmatrelvir | SARS-CoV | |
PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) . | |||
T9458 | PF-00835231 | SARS-CoV | |
PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.PF-00835231 is the active compound of the first anti-3CLpro regimen i... | |||
T21727 | Ivermectin B1a | SARS-CoV , Parasite | |
Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a. | |||
T7872 | Monolaurin | Others | |
Monolaurin is a surfactant and emulsifer found in coconut oil. It inhibitis growth of Staphylococcus, Streptococcus, Gardnerella, Candida, and Haemophilus, and decreases production of pro-inflammatory cytokines. | |||
T40276 | GS-621763 | SARS-CoV | |
GS-621763, a prodrug of GS-441524, exhibits antiviral activity against SARS-CoV-2 pathogenesis. | |||
T9672 | GRL-0496 | SARS-CoV | |
GRL-0496 is a potent inhibitor with an enzyme inhibitory activity against SARS-CoV 3CLpro with an IC50 of 30 nM and antiviral potency with an EC50 value of 6.9 μM. | |||
T9618 | HeE1-2Tyr | SARS-CoV | |
HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. It significantly inhibits West Nile, Dengue and SARS-CoV-2 RdRps (IC50 of 27.6 µM) activity in vitro. | |||
T11464 | GRL0617 | SARS-CoV , DUB | |
GRL0617 is a selective and competitive SARS-CoVPLpro and deubiquitinase noncovalent inhibitor(IC50 : 0.6 μM, Ki : 0.49 μM). | |||
T1303 | Auranofin | SKF-39162 | Others , SARS-CoV , Antibacterial |
Auranofin (SKF-39162) is an antirheumatic agent, is used to treat rheumatoid arthritis, improves arthritis symptoms including painful or tender and swollen joints and morning stiffness. | |||
T8371 | ML188 | Virus Protease , SARS-CoV | |
ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity. | |||
T6738 | Z-FA-FMK | SARS-CoV , Cysteine Protease | |
Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases. | |||
T5126 | Glecaprevir | ABT-493 | HCV Protease , SARS-CoV |
Glecaprevir (ABT-493) is an HCV NS3/4A protease inhibitor, (IC50s: 3.5-11.3 nM). | |||
T4547 | Grazoprevir | MK-5172 | HCV Protease , SARS-CoV |
Grazoprevir (MK-5172) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.08 nM (gt2a), 0.90 nM (gt3a), 0.01 nM (gt1b), ... | |||
T6200 | Ledipasvir | GS-5885 | HCV Protease , SARS-CoV |
T0211 | Azelastine | Azelastina,Astelin,Azelastinum | SARS-CoV , Histamine Receptor |
T7903 | Saquinavir | Ro 31-8959 | SARS-CoV , HIV Protease |
Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS. | |||
T60014 | SHEN26 | Antiviral | |
SHEN26 has antiviral activity and can be used in research on the treatment of viral infections. | |||
T1307 | Carmofur | HCFU | Nucleoside Antimetabolite/Analog , Virus Protease , SARS-CoV , DNA/RNA Synthesis |
Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy. | |||
T22323 | Enoxaparin sodium | Thrombin | |
Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment myocardial infarction (STEMI), or STEMI with subsequent percu... | |||
T3334 | Velpatasvir | GS-5816 | HCV Protease , SARS-CoV |
Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a high barrier to resistance in HCV replicon assays. GS-5816 d... | |||
T9341 | Bemnifosbuvir | AT-511 | Others , HCV Protease , SARS-CoV |
Bemnifosbuvir (AT-511) is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV. | |||
T4474 | Asunaprevir | BMS-650032 | HCV Protease , SARS-CoV |
Asunaprevir (BMS-650032) is an effective hepatitis C virus (HCV) NS3 protease inhibitor. | |||
T12502 | PLpro inhibitor | SARS-CoV | |
PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6 uM) | |||
T8676 | FOY 251 | Others , Serine/threonin kinase , SARS-CoV | |
FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate. | |||
T9331 | Bemnifosbuvir hemisulfate | AT-527 | HCV Protease , SARS-CoV |
Bemnifosbuvir hemisulfate (AT-527) is a potent inhibitor of HCV virus replication. | |||
T2486 | IOWH-032 | IOWH032,IOWH 032 | CFTR , Autophagy |
IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea. | |||
T9716 | Ensitrelvir | S-217622 | SARS-CoV |
Ensitrelvir (S-217622) is an orally active inhibitor of SARS-CoV-2 3CL protease with IC50 of 13 nM. | |||
T6040 | Aloxistatin | E64d,Loxistatin,E64c ethyl ester | SARS-CoV , Cysteine Protease |
Aloxistatin (E64d) is an inhibitor of cysteine protease with blood platelet aggregation inhibiting activity. Aloxistatin is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with... | |||
T9066 | Merafloxacin | CI 934 | SARS-CoV |
Merafloxacin (CI 934) is a fluoroquinolone antibacterial, which was also identified as a 1 PRF inhibitor of SARS-CoV-2. | |||
T7766 | Remdesivir | GS-5734 | SARS-CoV , DNA/RNA Synthesis |
Remdesivir (GS-5734) is a nucleoside analog, a broad-spectrum antiviral compound that exerts its activity by inhibiting the RNA-dependent RNA polymerase of viruses. Remdesivir is active against Ebola, SARS, and MERS viru... | |||
T22394 | Paritaprevir | ABT450,ABT-450,Veruprevir | HCV Protease |
Paritaprevir (ABT450) is an inhibitor of non-structural protein 3/4A protease with EC50 values of 1 and 0.21 nM for HCV 1a and HCV 1b, respectively. | |||
T1817 | GNF-2 | GNF2 | SARS-CoV , Bcr-Abl |
GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl. | |||
T1623 | Lopinavir | ABT-378 | SARS-CoV , HIV Protease |
Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins than the structurally-related dr... | |||
T7222 | GS-441524 | GS 441524 triphosphate | Others , SARS-CoV , DNA/RNA Synthesis |
GS-441524 treatment of cats with naturally occurring feline infectious peritonitis. | |||
T0211L | Azelastine hydrochloride | Optivar,Azelastine HCl,Allergodil,Astelin | SARS-CoV , Histamine Receptor |
Azelastine hydrochloride (Astelin) is a phthalazinone derivative with antihistaminergic activity. | |||
T8688 | (Rac)-X77 | CPD77,MUN91789 | SARS-CoV |
(Rac)-X77 (MUN91789) is a potent SARS- CoV- 2 main protease inhibitor. | |||
T9287 | Hydroxychloroquine | 2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol | SARS-CoV , TLR , Parasite , Autophagy |
Hydroxychloroquine (2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol) (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9. It i... | |||
T0951 | Hydroxychloroquine sulfate | Acidum iopanoicum,HCQ sulfate | DNA , SARS-CoV , TLR , Parasite , Autophagy |
Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in ... | |||
T2392 | Nafamostat mesylate | FUT-175 | Apoptosis , Serine/threonin kinase , SARS-CoV , Serine Protease |
Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. | |||
T0860 | Mefloquine hydrochloride | Mefloquin hydrochloride,Mefloquine HCl | Potassium Channel , SARS-CoV , Reactive Oxygen Species , Parasite , Autophagy |
Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria. | |||
T0828 | Bromhexine hydrochloride | Bromhexine HCl,Auxit,Bisolvon | SARS-CoV , HIV Protease , Autophagy |
Bromhexine hydrochloride (Bisolvon) is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. | |||
T6573 | E 64c | NSC 694279,EP 475,Loxistatin Acid | SARS-CoV , Cysteine Protease |
E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor. | |||
T2391 | Camostat mesylate | FOY-S980,FOY305,Camostat mesilate | Serine/threonin kinase , SARS-CoV , Sodium Channel |
Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function. | |||
T6388 | Amprenavir | 141W94,Prozei,KVX-478,VX-478 | SARS-CoV , HIV Protease |
Amprenavir (KVX-478) is a synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (HIV) protease. | |||
T0104 | Umifenovir hydrochloride | Arbidol hydrochloride,Arbidol HCl | SARS-CoV , Influenza Virus |
Umifenovir hydrochloride (Arbidol HCl) , an broad-spectrum antiviral chemical agent, can inhibit cell invade of enveloped viruses by blocking viral fusion with host cell membrane. | |||
T4988 | Boceprevir | SCH 503034,EBP 520 | HCV Protease , SARS-CoV |
Boceprevir (SCH 503034) is a novel, potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with Ki of 14 nM in both enzyme assay and EC90 of 350 nM in cell-based replicon assay. | |||
T5013 | Brequinar | Bipenquinate,NSC 368390,DUP785 | Virus Protease , Dehydrogenase , DNA/RNA Synthesis |
Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN3651 | Cichoriin | Others | |
Cichoriin is a photosensitive compound, it could be used as herbal photosensitizing agent in treating benign breast tumor in rats. | |||
T3S1447 | Arteannuin B | SARS-CoV , Ferroptosis | |
1. Arteannuin B has potent antimalarial activity. | |||
T40660 | Kansuinine B | IL Receptor , SARS-CoV | |
Kansuinine B inhibits Stat3 activation induced by IL-6. Kansuinine B exhibits anti-viral activity and could be used in COVID-19 research. | |||
TQ0180 | Chebulagic acid | SARS-CoV , Influenza Virus , Lipoxygenase , COX | |
Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor. | |||
TQ0302 | Thapsigargin | Apoptosis , SARS-CoV , Calcium Channel | |
Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer. Thapsigargin increases cytoplasmic calcium concentration by blocking ... | |||
T2869 | Emodin | Frangula emodin | SARS-CoV , Casein Kinase , Autophagy |
Emodin (Frangula emodin) is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in Y cells that are regulated by different signaling pathways. | |||
T1134 | Clofoctol | Antibacterial , Antibiotic | |
Clofoctol is a bacteriostatic antibiotic with activity against Gram-positive bacteria, used in the treatment of upper and lower respiratory tract infections. | |||
T3921 | Punicalagin | SARS-CoV , HBV | |
Punicalagin is a major ellagitannin found in pomegranates that is reported to produce antioxidant, anti-inflammatory, and anticancer effects. It has been shown to prevent high-fat diet-induced obesity-associated accumula... | |||
T9715 | Aplidine | SARS-CoV , DNA/RNA Synthesis | |
Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM). | |||
T6670 | Silymarin | Silybin B | SARS-CoV |
Silymarin (Silybin B) (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases. | |||
T2898 | Andrographolide | Andrographis | SARS-CoV , Influenza Virus , NF-κB , Autophagy |
Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential antineoplastic. | |||
T3319 | Scutellarein | 4',5,6,7-Tetrahydroxyflavone,6-Hydroxyapigenin | SARS-CoV , Src , Autophagy |
Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity. | |||
T0131 | Cepharanthine | NSC-623442 | Apoptosis , TNF , HIV Protease , Autophagy |
Cepharanthine (NSC-623442), a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and inhibits cytokine production. | |||
T3374 | Dihydrotanshinone I | DHTS,15,16-dihydrotanshinone I | SARS-CoV , ROS |
Dihydrotanshinone I (DHTS) is a natural compound extracted from Salvia miltiorrhiza Bunge used for treating of cardiovascular diseases. | |||
T8689 | Chloroquine | CQ | SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy |
Chloroquine is a Toll-like receptor inhibitor that inhibits autophagy. Chloroquine has anti-malarial and anti-inflammatory activity and is widely used in the treatment of malaria and rheumatoid arthritis. Chloroquine als... | |||
T3S0136 | 4'-O-Methylbavachalcone | O-Methylbroussochalcone B | SARS-CoV |
4'-O-Methylbavachalcone (O-Methylbroussochalcone B) is isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity (IC50: 10.1 μM). | |||
T7991 | 2-Hydroxycinnamic acid | Others , SARS-CoV , HIV Protease | |
2-Hydroxycinnamic acid is a natural product isolated from Angraecum fragrans, has photooxidant activity. | |||
T1131 | Ivermectin | MK-933 | Mitophagy , GluCls , P2X Receptor , SARS-CoV , HIV Protease , Antibiotic , Parasite , Autophagy , HSV |
Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity. | |||
T1188 | Mizoribine | Bredinin,NSC 289637,HE 69 | HCV Protease , SARS-CoV , Tyrosinase |
Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis. | |||
T0194 | Chloroquine phosphate | Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate | SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy |
Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs). | |||
T7060 | Amantadine | 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine | Others |
Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-02870 | SARS-CoV Nucleocapsid Protein (His) | SARS | Baculovirus Insect Cells |
SARS-CoV Nucleocapsid Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 47.5 kDa and the accession number is Q6S8E1. | |||
TMPY-05718 | SARS-CoV (Isolate Tor2) Spike S1+S2 ECD Protein (S577A, His) | SARS | Baculovirus Insect Cells |
SARS-CoV (Isolate Tor2) Spike S1+S2 ECD Protein (S577A, His) is expressed in Baculovirus insect cells. The predicted molecular weight is 132.58 kDa and the accession number is NP_828851.1. | |||
TMPY-05817 | SARS-CoV Spike/RBD Protein (His), Biotinylated | SARS | Baculovirus Insect Cells |
SARS-CoV Spike/RBD Protein (His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is Q5DIC5. | |||
TMPY-05699 | SARS-CoV Spike/S1 Protein (His), Biotinylated | SARS | Baculovirus Insect Cells |
SARS-CoV Spike/S1 Protein (His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 74.4 kDa and the accession number is Q5DIC5. | |||
TMPY-06204 | SARS-CoV (Isolate Tor2) Spike RBD Protein (His & Avi), Biotinylated | SARS | HEK293 Cells |
SARS-CoV (Isolate Tor2) Spike RBD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.4 kDa and the accession number is NP_828851.1. | |||
TMPY-05702 | SARS-CoV Spike/S1 Protein (mFc) | SARS | HEK293 Cells |
SARS-CoV Spike/S1 Protein (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 99.40 kDa and the accession number is Q5DIC5. | |||
TMPY-04177 | SARS-CoV Spike/RBD Protein (rFc) | SARS | Baculovirus Insect Cells |
SARS-CoV Spike/RBD Protein (rFc) is expressed in Baculovirus insect cells with rFc tag. The predicted molecular weight is 50.2 kDa and the accession number is Q5DIC5. | |||
TMPY-05722 | SARS-CoV Spike S2 Protein (His) | SARS | Baculovirus Insect Cells |
SARS-CoV Spike S2 Protein (His) is expressed in Baculovirus insect cells. The predicted molecular weight is 59.65 kDa and the accession number is NP_828851.1. | |||
TMPY-03988 | SARS-CoV Spike/S1 Protein (His) | SARS | Baculovirus Insect Cells |
SARS-CoV Spike/S1 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 74.4 kDa and the accession number is Q5DIC5. | |||
TMPY-05701 | SARS-CoV Spike/RBD Protein (mFc) | SARS | HEK293 Cells |
SARS-CoV Spike/RBD Protein (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 51.40 kDa and the accession number is Q5DIC5. | |||
TMPY-06176 | SARS-CoV (Isolate Tor2) Spike S1+S2 Protein (S577A, His), Biotinylated | SARS | Baculovirus Insect Cells |
SARS-CoV (Isolate Tor2) Spike S1+S2 Protein (S577A, His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 132.58 kDa and the accession number is NP_828851.1. | |||
TMPY-03224 | SARS-CoV Spike/RBD Protein (His) | SARS | Baculovirus Insect Cells |
SARS-CoV Spike/RBD Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is Q5DIC5. | |||
TMPY-06372 | SARS-CoV Spike RBD Protein (mFc), Biotinylated | SARS | HEK293 Cells |
SARS-CoV Spike RBD Protein (mFc), Biotinylated is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 51.49 kDa and the accession number is AAX16192.1. | |||
TMPJ-01449 | 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant | SARS-CoV-2 | E. coli |
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precur... | |||
TMPJ-01448 | 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His) | 2019-nCoV | E. coli |
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precur... | |||
TMPK-00705 | MASP2 Protein, Human, Recombinant (His) | Human | E. coli |
The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As... | |||
TMPY-05727 | SARS-CoV-2 3CLpro/3C-like protease Protein (His & Avi) | SARS-CoV-2 | E. coli |
3C-like protease (3CLpro) is the main protease of Humann Coronavirus. 3C-like protease (3CLpro) is a key enzyme, as it cleaves several sites to produce non-structural proteins that are essential for genome replication an... | |||
TMPY-05752 | SARS-CoV-2 3CLpro/3C-like protease Protein (His) | SARS-CoV-2 | Baculovirus Insect Cells |
3C-like protease (3CLpro) is the main protease of Humann Coronavirus. 3C-like protease (3CLpro) is a key enzyme, as it cleaves several sites to produce non-structural proteins that are essential for genome replication an... | |||
TMPY-05693 | SARS-CoV-2 Methyltransferase/ME Protein (His) | SARS-CoV-2 | E. coli |
Coronavirus encodes the 2’-O-MTase (2'O Methyltransferase) that is composed of the catalytic subunit nsp16 and the stimulatory subunit nsp10 and plays an important role in virus genome replication and evasion from innate... | |||
TMPY-06416 | SARS-CoV-2 NSP8 Protein | SARS-CoV-2 | E. coli |
NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarka... | |||
TMPH-02236 | TMPRSS2 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... | |||
TMPY-05749 | SARS-CoV-2 NSP8 Protein (Avi) | SARS-CoV-2 | E. coli |
NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarka... | |||
TMPH-02239 | TMPRSS4 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC.; (Microbial infection) In gut epithelia... | |||
TMPH-02237 | TMPRSS2 Protein, Human, Recombinant (His & Myc) | Human | HEK293 Cells |
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-... | |||
TMPK-01341 | 3CLpro/3C-like Protease Protein (P132H), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPK-01343 | 3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPK-01339 | 3CLpro/3C-like Protease Protein (S144A), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPK-01344 | 3CLpro/3C-like Protease Protein (L167F), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPK-01337 | 3CLpro/3C-like Protease Protein (Q189K), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPK-01336 | 3CLpro/3C-like Protease Protein (L50F, E166V), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPK-01347 | 3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPK-01335 | 3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPK-01346 | 3CLpro/3C-like Protease Protein (L50F), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPK-01342 | 3CLpro/3C-like Protease Protein (A191V), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPK-01338 | 3CLpro/3C-like Protease Protein (H172Y), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPK-01340 | 3CLpro/3C-like Protease Protein (F140A), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPH-01284 | EEF1A1 Protein, Human, Recombinant | Human | E. coli |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF... | |||
TMPH-01283 | EEF1A1 Protein, Human, Recombinant (His) | Human | E. coli |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF... | |||
TMPK-01348 | 3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306) | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPK-01345 | 3CLpro/3C-like Protease Protein (L50F, E166A, L167F), SARS-COV-2, Recombinant | SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al... | |||
TMPK-00439 | SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated | SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPY-06012 | SARS-CoV-2 NSP10 Protein | SARS-CoV-2 | E. coli |
NSP10 is a major regulator of coronavirus replicase function. NSP10 contains two zinc fingers and binds and stimulates both NSP14 and NSP16 activities. Researchers has found that the nsp10 surface that interacts with nsp... | |||
TMPK-00913 | SARS Spike S1 Protein (His & Avi), Biotinylated | SARS | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00433 | SARS-COV-2 Spike S1 Protein (hFc & Avi), Biotinylated | SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00434 | SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated | SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00908 | SARS Spike S1 Protein (hFc & Avi) | SARS | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00912 | SARS Spike RBD Protein (His & Avi), Biotinylated | SARS | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00437 | SARS-COV-2 Spike RBD Protein (His & Avi) | SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00440 | SARS-COV-2 Spike S1 Protein (His & Avi), Biotinylated | SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00432 | SARS-COV-2 Spike S1 Protein (hFc & Avi) | SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
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カタログ番号 | 製品名 | ||
---|---|---|---|
L1710 | Anti-COVID-19 Compound Library | 1133 compounds | |
A unique collection of 1133 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents; |