| T0129 |
Sanguinarine chloride
|
Pseudochelerythrine chloride,Sanguinarium chloride |
Apoptosis
,
EGFR
,
VEGFR
,
Antibacterial
,
Parasite
,
Autophagy
|
|
Sanguinarine chloride (Pseudochelerythrine chloride), a benzophenanthridine alkaloid, stimulates apoptosis by activating the production of reactive oxygen species (ROS). |
| T4S1321 |
(+)-Magnoflorine chloride
|
Magnoflorine chloride,Corytuberine methochloride,Thalictrine chloride,Escholine chloride |
Others
,
Antifungal
|
|
(+)-Magnoflorine chloride (Escholine chloride) has anti-inflammatory activity, it can inhibit inflammations. |
| T9862 |
Pseudocoptisine chloride
|
Isocoptisine chloride |
AChE
|
|
Pseudocoptisine chloride (Isocoptisine chloride) is isolated from Corydalis Tuber with anti-inflammatory and anti-amnestic properties. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity (IC50 = 12.8 μ... |
| T4912 |
Jatrorrhizine chloride
|
Yatrorhizine chloride,Neprotine chloride |
Others
,
5-HT Receptor
,
OCT
,
Antibacterial
,
AChE
|
|
Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 h... |
| T3406 |
Kuromanin chloride
|
Glucocyanidin chloride,Chrysontemin,Chrysontemin chloride,Cyanidin 3-O-glucoside chloride |
NF-κB
|
|
Kuromanin chloride (Chrysontemin chloride) is potent antioxidants and free radical scavengers, may act as modulators of gene regulation and signal transduction pathways. |
| TN6783 |
Corysamine chloride
|
CORYSAMINE CHLORIDE(RG) |
AChE
|
|
Corysamine chloride (CORYSAMINE CHLORIDE(RG)) was identified to inhibit the activity of ACHE. |
| T4S0795 |
Berberrubine chloride
|
9-Berberoline Chloride,Beroline,Beroline Chloride,Berberrubine,9-Berberoline |
IL Receptor
|
|
1. Berberrubine chloride (9-Berberoline Chloride) has antitumor activity. 2. Berberrubine has antidiabetic activity. 3. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expressio... |
| T10990 |
Dehydrocorydaline chloride
|
13-Methylpalmatine chloride |
BCL
,
PARP
,
p38 MAPK
,
Caspase
,
Parasite
,
Autophagy
|
|
Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK. |
| TN1043 |
Keracyanin chloride
|
Cyanidin-3-O-rutinoside chloride,Cyanidin 3-rutinoside chloride,Cyanidin 3-O-rutinoside chloride |
COX
|
|
Keracyanin chloride (Cyanidin 3-rutinoside chloride), an anthocyanin compound, exhibits antioxidant properties. It effectively prevents the formation of malonaldehyde in oxidized calf thymus DNA, underlining its potentia... |
| T4925 |
Thiamine monophosphate chloride (dihydrate)
|
Thiamine monophosphate chloride dihydrat,Aneurine monophosphate chloride |
Others
,
Endogenous Metabolite
|
|
Thiamine monophosphate chloride dihydrate (Aneurine monophosphate chloride) is a compound used in the screening of ligands that promote protein stability |
| T1221 |
Acetylcholine chloride
|
ACh chloride,Pilofrin |
Calcium Channel
,
Endogenous Metabolite
,
AChR
|
|
Acetylcholine Chloride is the chloride salt form of acetylcholine, a synthetic, quaternary amino alcohol with cholinergic properties. Acetylcholine chloride (Pilofrin) mimics the parasympathomimetic effect of the endogen... |
| TN1106 |
Cyanidin-3-O-galactoside chloride
|
Ideain chloride |
Antioxidant
|
|
Cyanidin-3-O-galactoside chloride (Ideain chloride), extracted from hawthorn pericarp (EPHF), has antioxidant activity and can be used in obesity research. |
| T6475 |
(±)-Carnitine chloride
|
Monocamin,DL-Carnitine HCl,Bicarnesine,DL-Carnitine chloride |
Reactive Oxygen Species
|
|
(±)-Carnitine chloride (Monocamin) is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine. |
| TN1564 |
Delphinidin 3-glucoside chloride
|
Delphinidin-3-O-glucoside chloride |
Apoptosis
,
EGFR
|
|
Delphinidin 3-glucoside chloride (Delphinidin-3-O-glucoside chloride) is a dietary phenolic substance found in Hibiscus sabdariffa extracts. Delphinidin 3-glucoside chloride has antioxidant activity, induces pro-apoptoti... |
| T4713 |
Phosphorylcholine chloride calcium salt tetrahydrate
|
Phosphocholine chloride calcium salt tet,CalciuM Phosphorylcholine Tetrahydrate |
Others
,
Endogenous Metabolite
|
|
Phosphorylcholine chloride calcium salt tetrahydrate (Phosphocholine chloride calcium salt tet) is a small haptenic molecule, is found in a wide variety of organisms. Human hepatic tumors undergo an elevation in the conc... |
| TN1567 |
Delphinidin chloride
|
|
Estrogen Receptor/ERR
,
VEGFR
|
|
Delphinidin chloride, a natural plant pigment found in berries and red wine, is a precursor of certain anthocyanins. Delphinidin chloride induces the release of nitric oxide from the vascular endothelium, resulting in va... |
| T5855 |
Edrophonium chloride
|
|
AChE
|
|
Edrophonium chloride is an acetylcholinesterase (AChE) inhibitor that is known to prevent the breakdown of the neurotransmitter acetylcholine by binding specifically to its catalytic site. |
| T5S0777 |
Phellodendrine chloride
|
|
Others
|
|
Phellodendrine chloride has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli. |
| T5528 |
Cyanidin Chloride
|
|
Antioxidant
|
|
Cyanidin Chloride, the main phenolic antioxidant in the grape (Vitis vinifera), in particular in the liposomal forms, could be used for treatment of diabetes mellitus complications. |
| TN1058 |
Pelargonidin chloride
|
|
NOS
,
Reactive Oxygen Species
,
Nrf2
,
NO Synthase
|
|
Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway. |
| TN1895 |
Luteolinidin chloride
|
|
CD38
|
|
Luteolinidin chloride is a natural product. It is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo. |
| T0019 |
Betaine chloride
|
Betaine hydrochloride |
Others
,
Chloride channel
,
Endogenous Metabolite
|
|
Betaine chloride (Betaine hydrochloride) is an acidic form of betaine, a vitamin-like substance observed in grains and other foods; gains the amplification of DNA by decreasing the formation of secondary structure in GC-... |
| TN1189 |
13-Methylberberine chloride
|
13-Methylberberine |
Others
|
|
13-Methylberberine chloride shows anti-adipogenic effect on 3T3-L1 adipocytes, it has potential as an anti-obesity drug |
| T4827 |
Trimethylammonium chloride
|
Trimethylamine hydrochloride |
Others
,
Endogenous Metabolite
|
|
Trimethylammonium chloride (Trimethylamine hydrochloride) is a product of decomposition of plants and animals. It is the substance mainly responsible for the fishy odor often associated with fouling fish, bacterial vagin... |
| T3419 |
Chelerythrine chloride
|
|
Apoptosis
,
BCL
,
PKC
,
Autophagy
|
|
Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. |
| T1039 |
Choline chloride
|
Biocolina,Biocoline,Hepacholine |
AChR
|
|
Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in li... |
| T5S0761 |
Nitidine chloride
|
|
Apoptosis
,
ERK
,
FAK
,
p38 MAPK
,
NF-κB
,
Topoisomerase
,
STAT
,
Parasite
|
|
1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id... |
| T2718 |
Palmatine chloride
|
|
Others
,
Indoleamine 2,3-Dioxygenase (IDO)
,
Aurora Kinase
|
|
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties. |
| T7908 |
DL-Methionine Methylsulfonium Chloride
|
|
Others
|
|
DL-Methionine Methylsulfonium Chloride is a natural product, used in the treatment of peptic ulcers, colitis, and gastritis. |
| T5S0056 |
Coptisine chloride
|
Q-100696,NSC-119754 |
Indoleamine 2,3-Dioxygenase (IDO)
,
Influenza Virus
,
Antibacterial
|
|
1. Coptisine chloride (NSC-119754) can be absorbed across intestinal epithelial cells, and completely absorbed compounds. |
| T0461 |
Berberine chloride
|
Berberine hydrochloride,Benzodioxide,Natural Yellow 18 |
Reactive Oxygen Species
,
Topoisomerase
,
Antibacterial
,
Antibiotic
,
Autophagy
|
|
Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae and also found in many other plants. It is relatively toxic to parenterally but has been used orally for various fungal an... |
| T2927 |
Trigonelline chloride
|
Gynesine Hydrochloride,Coffearine Hydrochloride,Nicotinic acid N-methylbetaine Hydrochloride,Trigonelline hydrochloride |
Others
,
Antibacterial
,
Antifungal
,
HSV
|
|
Trigonelline chloride (Coffearine Hydrochloride), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee. |
| T5515 |
Hemin
|
Hemin chloride |
Mitophagy
,
Ferroptosis
,
Autophagy
|
|
Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer. Hemin has therapeutic activity in porphyrias by reducing heme deficiency in patients, thereby inhibiting δ-aminolevulini... |
| T6220 |
Nicotinamide riboside chloride
|
|
Sirtuin
,
Endogenous Metabolite
|
|
Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+. |
| T4702 |
(3-Carboxypropyl)trimethylammonium chloride
|
γ-Butyrobetaine hydrochloride,(3-Carboxypropyl)trimethylammonium chlor |
Endogenous Metabolite
|
|
(3-Carboxypropyl)trimethylammonium chloride ((3-Carboxypropyl)trimethylammonium chlor) is a synthetic carnitine related compound used as a transporter substrate in the cloning and sequencing of human carnitine transporte... |
| T82694 |
Columbamine chloride
|
Columbamin chloride,Dehydroisocorypalmine chloride |
|
|
Columbamine chloride, also known as Columbamin and Dehydroisocorypalmine, is an alkaloid [1]. |
| T2O2741 |
Thiamine monochloride
|
Thiamine chloride,Vitamin B1 |
Others
,
Antioxidant
,
Endogenous Metabolite
,
Antibacterial
|
|
Thiamine monochloride (Vitamin B1) is an essential vitamin with erythropoietic, glucose-regulatory, antioxidant, and mood-regulatory properties.Thiamine monochloride inhibits lead-induced lipid peroxidation, thereby prev... |
| T8306 |
Epiberberine chloride
|
Epiberberine (chloride) |
Reactive Oxygen Species
,
Beta-Secretase
,
BACE
,
AChR
,
AChE
|
|
Epiberberine chloride (Epiberberine (chloride)) is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor (IC50s: 1.07, 6.03 and 8.55 μM). |
| T4874 |
Thiamine pyrophosphate
|
Cocarboxylase,Aneurinepyrophosphoric acid,Thiamine pyrophosphate chloride |
Endogenous Metabolite
|
|
Thiamine pyrophosphate (Cocarboxylase) is a vitamin B-1 derivative that acts as a coenzyme of transketolase. Thiamine pyrophosphate is used in studies to assess decarboxylation mechanisms in biological systems. |
| TN1909 |
Malvidin-3-glucoside chloride
|
Malvidin-3-O-glucoside chloride,Oenin chloride |
Others
|
|
Malvidin-3-glucoside chloride (Oenin chloride) has antioxidant activity, alone is not oxidized in the presence of grape polyphenol oxidase. Malvidin-3-O-glucoside chloride's color stabilization at a higher pH can be expl... |
| TN2050 |
Peonidin-3-O-glucoside chloride
|
Peonidin 3-Glucoside Chloride |
Free radical scavengers
|
|
Peonidin-3-O-glucoside chloride (Peonidin 3-Glucoside Chloride) is an anthocyanin with radical scavenger activity and can be used in studies about acting as an insulin secretagogue. |
| T31129 |
Cyclanoline chloride
|
l-alpha-N-Methylscoulerine,Cissamine chloride |
|
|
Cyclanoline chloride is a bioactive chemical. |
| T14545 |
Berberine chloride hydrate
|
Natural Yellow 18 chloride hydrate |
Reactive Oxygen Species
,
Topoisomerase
,
Endogenous Metabolite
,
Antibacterial
,
Antibiotic
,
Parasite
,
Autophagy
|
|
Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid commonly used as an antibiotic.Berberine chloride hydrate has antitumor activity, induces the generation of reactive oxygen species (ROS), an... |
| T0415 |
Guanidine hydrochloride
|
Guanidine HCl,Aminoformamidine HCl,Aminoformamidine Hydrochloride,Guanidinium chloride |
Others
,
Arginase
,
DNA/RNA Synthesis
,
Endogenous Metabolite
,
Autophagy
|
|
Guanidine hydrochloride (Aminoformamidine Hydrochloride) is a strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also u... |
| TN1565 |
Delphinidin 3-rutinoside chloride
|
Delphinidin-3-O-rutinoside chloride |
Others
|
|
Delphinidin-3-O-rutinoside chloride has antioxidant activity. |
| TN1104 |
Cyanidin 3-sambubioside chloride
|
Cyanidin-3-O-sambubioside chloride |
NF-κB
,
ROS
|
|
Cyanidin-3-O-sambubioside chloride is inhibitors of BPDE-induced NF-kB activity. It inhibits the enzyme activity by competing with the substrate for the active site. Cyanidin-3-O-sambubioside chloride has antioxidant act... |
| TN1908 |
Malvidin-3-galactoside chloride
|
Malvidin-3-O-galactoside chloride |
Others
|
|
Malvidin-3-O-galactoside chloride has antioxidant activity. |
| T4853 |
TRIA-662
|
3-Carbamoyl-1-methylpyridinium Chloride,1-Methylnicotinamide chloride,1-methylpyridin-1-ium-3-carboxamide hydrochloride,Nicotinamide Chloromethylate |
Others
,
Endogenous Metabolite
|
|
TRIA-662 (Nicotinamide Chloromethylate) is a niacin metabolite excreted via the urinary system. |
| T5066 |
Nε,Nε,Nε-Trimethyllysine chloride
|
Lys(Me)3-OH Chloride,Nε,Nε,Nε-Trimethyllysine hydrochloride |
Others
,
Endogenous Metabolite
|
|
Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) is a methylated derivative of the amino acid lysine. It is a component of histone proteins, a precursor of carnitine and a coenzyme of fatty acid oxidation. Nε,Nε,... |
| T0894 |
Thiamine hydrochloride
|
Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,Thiamine chloride hydrochloride |
Apoptosis
,
HBV
,
Endogenous Metabolite
|
|
Thiamine hydrochloride (Vitamin B1) is the hydrochloride salt form of thiamine, a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Upon hydrolysis, Thiami... |
