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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T13486 | Neurodegenerative Disorder-Targeting Compound 1 | Others | |
Neurodegenerative Disorder-Targeting Compound 1 is an inhibitor of calpain [1]. | |||
T10059 | Neuromuscular Disorder-Targeting Compound 1 | Others | |
Neuromuscular Disorder-Targeting Compound 1 is a compound used in the research of neuromuscular disorders, for example, symptoms of chronic fatigue syndrome and fibromyalgia syndrome. | |||
T83527 | (Rac)-Neurodegenerative Disorder-Targeting Compound 1 | ||
(Rac)-Neurodegenerative Disorder-Targeting Compound 1 is a calpain inhibitor. | |||
T8337 | Nequinate | Xanthine Oxidase , Parasite | |
Nequinate is an anticoccidial agent, preventing coccidiosis . | |||
T1279 | Vilazodone | SB659746A,EMD 68843 | 5-HT Receptor , Serotonin Transporter |
Vilazodone (SB659746A) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and a 5-HT-1A receptor partial agonist, with antidepressant and anti-anxiety activities. Vilazodone inhibits the reuptake of serotonin from... | |||
T7688 | 4-Nonylphenylboronic acid | FAAH | |
4-Nonylphenylboronic acid is a inhibitor of FAAH. | |||
T8318 | BNC210 | H-Ile-Trp-OH,IW-2143 | AChR |
BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression. | |||
T22994 | ML 154 | Neuropeptide Y Receptor | |
neuropeptide S receptor (NPSR) antagonist | |||
T9183 | Ralmitaront | RO6889450 | Others |
Ralmitaront (RO6889450) is a potent, orally active partial agonist of the trace amine-associated receptor 1 (TAAR1). | |||
T7061 | Duloxetine | Serotonin Transporter | |
Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder. | |||
T2216 | Entacapone | OR-611 | Transferase |
Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT). | |||
T13189 | TP-10 | PDE | |
T2200 | Hydroxyzine dihydrochloride | Hydroxyzine 2HCl | Histamine Receptor |
Hydroxyzine dihydrochloride (Hydroxyzine 2HCl) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIR... | |||
TQ0046 | Bavisant | JNJ-31001074 | Histamine Receptor |
Bavisant (JNJ-31001074) is a selective and orally active Human H3 receptor antagonist. Bavisant can be used in research on mechanisms of action, involving wakefulness and cognition and the treatment for ADHD. | |||
T4297 | Flibanserin | BIMT-17BS,Girosa,BIMT-17 | Dopamine Receptor , 5-HT Receptor |
Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. Flibanserin has been associated with a low rate of minor serum aminotransferase elevations during treatment but has n... | |||
T8737 | GR 125743 | 5-HT Receptor | |
GR 125743 is a novel antagonist of 5-HT1B/1D receptor. | |||
T15799 | LY2940094 | LY-2940094 | Opioid Receptor |
LY2940094 (LY-2940094) decreases ethanol self-administration in animal models. LY2940094 is an effective, selective, and orally available nociceptin receptor antagonist with high affinity (Ki=0.105 nM) and antagonist pot... | |||
T1579 | Mestranol | Devocin,Norquen,Menophase | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Mestranol (Devocin), a semisynthetic estrogen, is used as an estrogen receptor agonist and must be demethylated to be biologically active. | |||
T14835 | BTRX-335140 | CYM-53093 | Opioid Receptor |
BTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. BTRX-335140... | |||
T2710 | TCS 1102 | OX Receptor | |
TCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2/3 nM for OX2/1 receptors). | |||
T11722 | JNJ-37822681 dihydrochloride | Dopamine Receptor | |
T3124 | Carbendazim | Bavistin,Carbendazole,Mercarzole | Antifungal |
Carbendazim (Mercarzole) is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspec... | |||
T60080 | TMPH | 2,2,6,6-Tetramethylpiperidin-4-yl heptanoate | AChR |
TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders. | |||
T4008 | Metergoline | Methergoline,Liserdol | Dopamine Receptor , 5-HT Receptor , Sodium Channel |
Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migraine disorder therapy. | |||
T14782 | Brilaroxazine | RP5063 | Dopamine Receptor , 5-HT Receptor |
Brilaroxazine (RP5063) is a potent multimodal dopamine/5-HT modulator. Brilaroxazine is a partial agonist of dopamine D2, D3, and D4 receptors, 5-HT1A (Ki =1.5 nM) and 5-HT2A (Ki = 2.5 nM), and has antagonist activity 5-... | |||
T7805 | GW791343 dihydrochloride | GW791343 (HCl) | P2X Receptor |
GW791343 dihydrochloride (GW791343 (HCl)) is a P2X7 allosteric modulator. | |||
T25487 | Haloperidol decanoate | KD 16,KD-136,KD 136,Neoperidole,Haldol | Others |
Haloperidol decanoate (KD 16) is a typical antipsychotic agent utilized as maintenance treatment for schizophrenia and mood disorders formulated as an ester for intramuscular injection. | |||
T3217 | PF-CBP1 hydrochloride | PF-CBP1 HCl | Epigenetic Reader Domain , Histone Acetyltransferase |
PF-CBP1 hydrochloride (PF-CBP1 HCl) is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).It inhibits CREBBP and p300 bromodomains with IC50 of 125 and 363 nM respectively. | |||
T0024 | Primidone | Primaclone,Mysoline,NCI-C56360 | GABA Receptor , Sodium Channel , GluR , AChR |
Primidone (NCI-C56360) is a potent anticonvulsant agent. It is a neuronal voltage-gated sodium channel blocker and has value in the study of epilepsy, essential tremor, and psychiatric disorders. | |||
T0482 | Sertraline hydrochloride | Sertraline HCl,CP-51974-1 HCl | 5-HT Receptor , Serotonin Transporter |
Sertraline hydrochloride (Sertraline HCl) is a selective serotonin uptake inhibitor that is used in the treatment of depression. | |||
T2371 | Emapunil | AC-5216,XBD-173 | Others |
Emapunil (XBD-173) is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO. | |||
T13690 | Etifoxine hydrochloride | HOE 36-801 hydrochloride | GABA Receptor |
Etifoxine hydrochloride (HOE 36-801 hydrochloride) is an anxiolytic and anticonvulsant drug. Unlike benzodiazepines, Etifoxine hydrochloride appears to produce its anxiolytic effects by binding to β2 and β3 subunits of t... | |||
T2150 | Guanfacine hydrochloride | Tenex,Intuniv,Guanfacine | Adrenergic Receptor |
Guanfacine hydrochloride (Intuniv) is a centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS. | |||
T1445 | Agomelatine | Thymanax,S-20098,Valdoxan | Melatonin Receptor , 5-HT Receptor |
Agomelatine (Valdoxan) is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. | |||
T0255 | Clomipramine hydrochloride | Clomipramine HCl,Anafranil | Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine , GST |
Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demeth... | |||
T21013 | Clomipramine | Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina | 5-HT Receptor |
Clomipramine (Clomicalm) is a tricyclic antidepressant (TCA). It is used for the treatment of the panic disorder, obsessive-compulsive disorder, major depressive disorder, and chronic pain. It may decrease the risk of su... | |||
T1602 | Valproic acid sodium salt | Sodium Valproate | Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , HDAC , Autophagy |
Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into its active form, valproate ion, in blood. Although the mecha... | |||
T0891 | Dapsone | DDS,4,4‘-Sulfonyldianiline,Bis(4-aminophenyl) sulfone,Sulphadione,4,4'-Diaminodiphenylsulfone,4-Aminophenyl sulfone | Reactive Oxygen Species , Antibacterial , Antibiotic , Parasite |
Dapsone (Sulphadione) has activity against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. | |||
T6461 | Dapoxetine hydrochloride | LY-210448,LY-210448 hydrochloride,Dapoxetine HCl,Priligy | 5-HT Receptor , Serotonin Transporter |
Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation. | |||
T6963 | Reboxetine mesylate | FCE20124 mesylate,Edronax,PNU155950E mesylate,PNU 155950E | Adrenergic Receptor , Norepinephrine |
Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor (Ki: 8.2 nM). | |||
T1471 | Duloxetine hydrochloride | Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl | Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine |
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and i... | |||
T6474 | Divalproex Sodium | Valproate semisodium,Epival | HDAC |
Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme... | |||
T12352L | Oxidopamine hydrobromide | 6-Hydroxydopamine hydrobromide,6-OHDA hydrobromide | Mitophagy , Dopamine Receptor , Autophagy |
Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist. | |||
T12352 | Oxidopamine hydrochloride | 6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride | Mitophagy , Dopamine Receptor , Autophagy |
Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist. | |||
T16083 | Mizagliflozin | GSK-1614235 free base,KGA-3235 free base,DSP-3235 free base | SGLT |
Mizagliflozin (GSK-1614235 free base) is a sodium-glucose transporter inhibitor( Ki of 27 nM for human SGLT1). Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic drug that ca... | |||
T0039 | Dapoxetine | Dapoxetina,Dapoxetinum | Others , 5-HT Receptor |
Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. | |||
T6526 | GW791343 trihydrochloride | GW791343 3HCl | P2X Receptor |
GW791343 trihydrochloride (GW791343 3HCl) is aHCl salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7. | |||
T22453 | Venlafaxine | Wy 45030 | Serotonin Transporter |
Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia. | |||
T28270 | Osemozotan HCl | Osemozotan hydrochloride,MN-305,MCI-242,MKC-242,MKC242,MCI242 | |
Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder. | |||
T4559 | Isocarboxazid | Monoamine Oxidase | |
Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor.[2] It is used in the treatment of major depression, dysthymic disorder, atypical disor... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T21883 | Gedunin | HSP | |
Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly in seeds. Gedunin is an Hsp90 inhibitor, and inhibits ovarian cancer cell proliferation. | |||
T20884 | Hydroxyzine | Hydroxyzine free base | Histamine Receptor |
Hydroxyzine (Hydroxyzine free base) is an antagonist of histamine H1-receptor. | |||
TN1008 | Psoralenoside | CaMK , Calcium Channel , Histamine Receptor | |
Psoralenoside is a natural product isolated from the fruits of Psoralea corylifolia, shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity. | |||
T3933 | Jatrorrhizine | Yatrorizine,neprotin | MAO , 5-HT Receptor , Antibacterial , AChE |
Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits mo... | |||
T4912 | Jatrorrhizine chloride | Yatrorhizine chloride,Neprotine chloride | Others , 5-HT Receptor , OCT , Antibacterial , AChE |
Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 h... | |||
T7064 | Valproic Acid | Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid | Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy |
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research. | |||
T5305 | 3-Methylbut-2-enoic acid | 3,3-Dimethylacrylic Acid,Senecioic acid,3-Methylcrotonic Acid | Others , Endogenous Metabolite |
3-Methylbut-2-enoic acid (Senecioic acid) appears in the urine of patients with 3-Methylcrotonic aciduria, which is a disorder characterized by urine that contains increased amounts of 3-methylcrotonic acid. | |||
TN1624 | Ethyl cinnamate | Calcium Channel , ROS , NO Synthase | |
Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction. Ethyl... | |||
T4852 | Trimyristin | Trimyristoylglycerol,Tritetradecanoin,Glyceryl trimyristate,1,2,3-Tritetradecanoylglycerol | Phosphatase , Endogenous Metabolite , AChE |
Trimyristin (Tritetradecanoin) is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ranging from yeast to humans. In humans, glyceryl trimyristate is i... | |||
T5231 | 2-Methylsuccinic acid | Pyrotartaric Acid,Methylbutanedioic acid | Others , Endogenous Metabolite |
2-Methylsuccinic acid (Pyrotartaric Acid) is a normal metabolite found in human fluids. Increased urinary levels of 2-Methylsuccinic acid (Pyrotartaric Acid) (together with ethylmalonic acid) are the main biochemical mea... | |||
T4781 | N-Acetyl-L-phenylalanine | N-Ac-Phenylalanine | Others , Endogenous Metabolite |
N-Acetyl-L-phenylalanine (N-Ac-Phenylalanine) is an essential amino acid produced for medical, feed, and nutritional applications. It appears in large amount in urine of patients with phenylketonuria which is a human gen... | |||
T4827 | Trimethylammonium chloride | Trimethylamine hydrochloride | Others , Endogenous Metabolite |
Trimethylammonium chloride (Trimethylamine hydrochloride) is a product of decomposition of plants and animals. It is the substance mainly responsible for the fishy odor often associated with fouling fish, bacterial vagin... | |||
T5219 | L-Alloisoleucine | L-allo-Isoleucine,(3R)-LS-Isoleucine,L(+)-Alloisoleucine | Others , Endogenous Metabolite |
L-Alloisoleucine (L-allo-Isoleucine) is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produced as a byproduct of... | |||
T4858 | 4-Hydroxyphenylpyruvic acid | 4-Hydroxyphenylpyruvic acid | Endogenous Metabolite |
4-Hydroxyphenylpyruvic acid is an enzyme inhibitor.4-Hydroxyphenylpyruvic acid (4-HPPA) is a keto acid that is involved in the tyrosine catabolism pathway. It is a product of the enzyme (R)-4-hydroxyphenyllactate dehydro... | |||
T4S2126 | Ginkgetin | Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy | |
1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ... | |||
T8274 | 3-Methyl-L-histidine | Endogenous Metabolite | |
3-Methylhistidine belongs to the class of organic compounds known as histidine and derivatives. Histidine and derivatives are compounds containing cysteine or a derivative thereof resulting from reaction of cysteine at t... | |||
T8053 | N-Acetyl-L-arginine | Ac-Arg-OH | Endogenous Metabolite |
N-Acetyl-L-arginine (Ac-Arg-OH) belongs to the class of organic compounds known as n-acyl-l-alpha-amino acids. These are n-acylated alpha amino acids which have the L-configuration of the alpha-carbon atom. N-a-Acetyl-L-... | |||
T38954 | L-Glyceric acid sodium | ||
L-Glyceric acid sodium is a urinary metabolite predominantly found in individuals with the rare inherited metabolic disorder, L-glyceric aciduria. This compound serves as a diagnostic tool for identifying primary hyperox... | |||
T7475 | S-Adenosyl-L-methionine | AdoMet,Ademetionine,SAMe,S-Adenosyl methionine | Others , Endogenous Metabolite |
S-Adenosyl-L-methionine (Ademetionine) is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder. | |||
T82682 | Convicine | ||
Convicine, a pyrimidine glycoside found in faba beans [1] [2], serves as the precursor for the aglycones Divicine and Isouramil, alongside Vicine. It is a principal factor in favism, a genetic disorder that causes severe... | |||
T37291 | Lyso-Globotriaosylceramide (d18:1) | Lyso-Globotriaosylceramide (d18:1) | |
Lyso-globotriaosylceramide is a form of globotriaosylceramide that is lacking the fatty acyl group. It binds to Shiga toxin 1 (Stx1) in the presence of cholesterol and phosphatidylcholine but does not bind Stx2. It also ... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-01104 | Coagulation factor XI/F11 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p... | |||
TMPY-02585 | Acid sphingomyelinase/SMPD1 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
Sphingomyelin phosphodiesterase 1 (SMPD1) , also known as ASM ( acid sphingomyelinase ), is a member of the acid sphingomyelinase family of enzymes. Three isoforms have been identified, isoform 1 is 631 amino acids (aa) ... | |||
TMPY-02078 | HtrA2/Omi Protein, Human, Recombinant (His) | Human | E. coli |
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the ... | |||
TMPY-01061 | FGF-10 Protein, Human, Recombinant | Human | E. coli |
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes... | |||
TMPY-02153 | TNF beta Protein, Human, Recombinant | Human | E. coli |
Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lympho... | |||
TMPY-02185 | Coagulation factor XIII B/F13B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ... | |||
TMPY-02648 | PACAP receptor/ADCYAP1R1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Pituitary adenylate cyclase activating polypeptide (PACAP, Adcyap1) activation of PAC1 receptors ( Adcyap1r1) significantly increases excitability of guinea pig cardiac neurons. This modulation of excitability is mediate... | |||
TMPY-01380 | Cyclophilin B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
PPIB is identified as a candidate gene for OI-IX. Osteogenesis imperfecta (OI) is an inherited disorder of connective tissue typically caused by defects in either COL1A1 or COL1A2. A number of other genes causative of th... | |||
TMPK-01376 | TROP-2 Protein, Mouse, Recombinant (aa 25-270, His) | Mouse | HEK293 Cells |
Trop-2,also known as epithelial glycoprotein-1 antigen (EGP-1),is a protein that in humans is encoded by the TACSTD2 gene.Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive di... | |||
TMPH-03262 | Cathepsin K Protein, Rat, Recombinant (His) | Rat | E. coli |
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in... | |||
TMPY-02394 | IMPA1 Protein, Human, Recombinant (His) | Human | E. coli |
IMPA1 (Inositol Monophosphatase 1) is a Protein Coding gene. This gene encodes an enzyme that dephosphorylates Myo-inositol monophosphate to generate free Myo-inositol, a precursor of phosphatidylinositol, and is, theref... | |||
TMPY-00569 | B3GAT3 Protein, Human, Recombinant (His) | Human | E. coli |
B3GAT3, encoding beta-1,3-glucuronyltransferase 3, has an important role in proteoglycan biosynthesis. Homozygous B3GAT3 mutations have been associated with short stature, skeletal deformities, and congenital heart defec... | |||
TMPY-00368 | ALR Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Alterations in GFER gene have been associated with progressive mitochondrial myopathy, congenital cataracts, hearing loss, developmental delay, lactic acidosis and respiratory chain deficiency in 3 siblings born to consa... | |||
TMPY-04302 | Frizzled 4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EV... | |||
TMPJ-00504 | Serpin A8 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hyperten... | |||
TMPY-00131 | Niemann Pick C1/NPC1 Protein, Human, Recombinant (His & FLAG) | Human | HEK293 Cells |
Niemann-Pick C1 (NPC1), a host receptor involved in the envelope glycoprotein (GP)-mediated entry of filoviruses into cells, is believed to be a major determinant of cell susceptibility to filovirus infection. Niemann-Pi... | |||
TMPJ-01034 | TIM Protein, Human, Recombinant (His) | Human | E. coli |
Triose-phosphate isomerase, also named Triose-phosphate isomerase, TPI and TIM, is an enzyme that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3... | |||
TMPY-00197 | Frizzled 4 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EV... | |||
TMPY-03310 | Frizzled 4 Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EV... | |||
TMPY-02377 | 14-3-3 eta/YWHAH Protein, Human, Recombinant (GST) | Human | E. coli |
YWHAH, the gene encoding the 14-3-3eta isoform, is highly expressed in retinal ganglion cells (RGC). YWHAH is a positional and functional candidate gene for both schizophrenia and bipolar disorder (BP). It is located on ... | |||
TMPY-04773 | TPK1 Protein, Human, Recombinant (His) | Human | E. coli |
Thiamine pyrophosphokinase (TPK) produces thiamine pyrophosphate, a cofactor for a number of enzymes, including pyruvate dehydrogenase and 2-ketoglutarate dehydrogenase. Episodic encephalopathy type thiamine metabolism d... | |||
TMPY-05009 | Asp f 1 Protein, Neosartorya fumigata, Recombinant (His) | Neosartorya fumigata | HEK293 Cells |
Asp f 1 (Aspergillus fumigatus allergen 1) is a major allergen produced by the mycelia of Aspergillus fumigatus. It is not present in spores and can be used as a specific marker for the detection of germination of this f... | |||
TMPJ-00540 | PEPD Protein, Human, Recombinant | Human | E. coli |
PEPD belongs to the peptidase M24B family of Eukaryotic-type prolidase subfamily. PEPD is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus. It is important in coll... | |||
TMPY-00313 | Frizzled 4 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EV... | |||
TMPJ-01092 | MGAT2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal... | |||
TMPJ-01057 | PSP Protein, Human, Recombinant (His) | Human | E. coli |
Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphose... | |||
TMPY-02544 | FANCA Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by h... | |||
TMPJ-01174 | Cystatin B Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Cystatin B, also called stefin B or liver thiol proteinase inhibitor, is a member of family 1 of the cystatin superfamily. Like Cystatin A, it is an intracellular inhibitor regulating the activities of cysteine proteases... | |||
TMPH-01061 | Cathepsin K Protein, Human, Recombinant (His) | Human | E. coli |
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in... | |||
TMPJ-01350 | XPNPEP3 Protein, Human, Recombinant (His) | Human | E. coli |
Probable Xaa-Pro Aminopeptidase 3 (XPNPEP3) is a member of the peptidase M24B family. XPNPEP3 has two isoforms and both are widely expressed. XPNPEP3 is localized in the Mitochondrion. XPNPEP3 catalyzes the release of an... | |||
TMPK-01158 | Kallikrein 5/KLK5 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
The inhibition of kallikrein 5 (KLK5) has been identified as a potential strategy for treatment of the genetic skin disorder Netherton syndrome, in which loss-of-function mutations in the SPINK5 gene lead to down-regulat... | |||
TMPY-04464 | GALK1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Galactokinase, also known as Galactose kinase, GALK and GALK1, is a protein which belongs to theGHMP kinase family and GalK subfamily. Galactokinase / GALK1 is a major enzyme for galactose metabolism. Galactokinase (G... | |||
TMPY-03852 | Dopamine beta-Hydroxylase Protein, Human, Recombinant (His) | Human | HEK293 Cells |
DBH is a 29 kDa copper-containing oxygenase. It can be detected in noradrenergic nerve terminals of the central and peripheral nervous systems, and is also expressed in chromaffin cells of the adrenal medulla. DBH conta... | |||
TMPJ-00763 | ANG Protein, Human, Recombinant | Human | E. coli |
Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular t... | |||
TMPJ-01114 | GAMT Protein, Human, Recombinant (His) | Human | E. coli |
GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily. It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver. GAMT converts guanidoa... | |||
TMPY-03756 | BBOX1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
BBOX1, also known as gamma-BBH, belongs to thegamma-BBH/TMLD family. It is highly expressed in kidney and moderately expressed in liver. BBOX1 catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last ste... | |||
TMPY-04318 | GRIK2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar... | |||
TMPJ-00660 | IMPase2 Protein, Human, Recombinant (His) | Human | E. coli |
Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylr... | |||
TMPY-03437 | DNAJC30 Protein, Human, Recombinant (His) | Human | E. coli |
DNAJC30 is a member of the DNAJ molecular chaperone homology domain-containing protein family. DNAJC30 gene is deleted in williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes... | |||
TMPJ-00815 | FBPase1 Protein, Human, Recombinant (His, E. coli) | Human | E. coli |
Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and... | |||
TMPY-03332 | PRTFDC1 Protein, Human, Recombinant (His) | Human | E. coli |
PRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG ... | |||
TMPY-03109 | PHYH Protein, Human, Recombinant | Human | E. coli |
PHYH belongs to the family of iron(II)-dependent oxygenases, which typically incorporate one atom of dioxygen into the substrate and one atom into the succinate carboxylate group. PHYH is expressed in liver, kidney, and ... | |||
TMPY-04303 | FAM20C Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
The Family with sequence similarity 20 member C (FAM20C) catalyzes the phosphorylation of secreted proteins, and participates in a variety of biological processes, including cell proliferation, migration, mineralization,... | |||
TMPY-06815 | SYAP1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Synapse-associated protein 1 (SYAP1), also known as PRO3113 and BSTA, belongs to the synapse-associated BSD domain family, featuring three α-helices and two conserved tryptophan and phenylalanine residues located at the ... | |||
TMPY-03985 | Adenosine Deaminase Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Adenosine Desaminase (ADA) deficiency, is a purine metabolic disorder that cause severe combined immunodeficiency (SCID) due to the accumulation of toxic metabolites that primarily affects development, differentiation a... | |||
TMPJ-00704 | SCO1 Protein, Human, Recombinant (GST) | Human | E. coli |
Protein SCO1 Homolog, Mitochondrial (SCO1) is a member of the SCO1/2 family. SCO1 has a homodimer structure. SCO1 is located in mitochondrion and is highly expressed in muscle, heart, and brain. It is characterized by hi... | |||
TMPJ-01343 | MYOZ2 Protein, Human, Recombinant (His) | Human | E. coli |
Myozenin 2 (MYOZ2) is a 264 amino acid protein that belongs to the myozenin family. MYOZ2 binds to Calcineurin, a phosphatase that is involved in calcium-dependent signal transduction in diverse cell types. MYOZ2 is one ... | |||
TMPJ-00280 | TNF R1 Protein, Mouse, Recombinant | Mouse | E. coli |
Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate t... | |||
TMPY-03455 | FGFR1OP Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
FOP( fibroblast growth factor receptor 1 oncogene partner) is a largely hydrophilic protein postulated to be a leucine-rich protein family member. FOP contains 1 LisH domain. A t(6;8)(q27;p11) chromosomal translocati... | |||
TMPJ-01277 | CRT2 Protein, Human, Recombinant | Human | E. coli |
Calreticulin-3 belongs to the calreticulin family, members of which are calcium binding chaperones localized mainly in the endoplasmic reticulum. It can be divided into a N-terminal globular domain, a proline-rich P-doma... | |||
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