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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T8527 | CPYPP | Others | |
CPYPP is an inhibitor of DOCK2-Rac1 interaction. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner(IC50 : 22.8 µM). CPY... | |||
T3481 | Bimolane | Topoisomerase | |
Bimolane is a topoisomerase II inhibitor. | |||
T6403 | Siponimod | BAF-312 | S1P Receptor , LPL Receptor |
BAF312 (Siponimod (BAF-312)), a next-generation S1P receptor modulator, is specific for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, respectively. The specificity of BAF312 for S1P1 and S1P5 receptors exhibi... | |||
T23256 | RS-25344 hydrochloride | PDE | |
RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor | |||
T6588 | Mitoxantrone | mitozantrone | Topoisomerase , PKC |
Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisome... | |||
T10765 | Eragidomide | CC-90009,Cereblon modulator 1 | Apoptosis , Ligand for E3 Ligase , Molecular Glues |
Eragidomide (CC-90009; Cereblon modulator 1) is a cereblon (CRBN) E3 ligase modulator. Eragidomide specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex. | |||
T7739 | L-Leucyl-L-Leucine methyl ester hydrochloride | Leu-Leu-ome hydrochloride | Others , Endogenous Metabolite |
L-Leucyl-L-Leucine methyl ester hydrochloride (Leu-Leu-ome hydrochloride) is a lysosomal condensation product that cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes. | |||
T0158 | Mitoxantrone dihydrochloride | Mitoxantrone 2HCl,Mitoxantrone hydrochloride,NSC-301739,mitozantrone dihydrochloride | Topoisomerase , PKC |
Mitoxantrone dihydrochloride (NSC-301739) is the hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. It is a type II topoisomerase inhibitor. | |||
T6933 | Peficitinib | ASP015K,JNJ-54781532 | Tyrosine Kinases , JAK |
Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3. | |||
T25705 | Imupedone | LF1695,LF-1695,LF 1695 | Others |
Imupedone (LF 1695) is a synthetic immunomodulator that modulates T lymphocytes and macrophages, induces T-cell differentiation of bone marrow precursor cells, and increases the proliferative response of lymphocytes to m... | |||
TP1758L | LCMV gp33-41 acetate | LCMV gp33-41 acetate(151705-84-9 Free base) | Others |
LCMV gp33-41 acetate is a sequence of lymphocytic choriomeningitis virus which restricted by major histocompatibility complex class I H-2Db and presented to cytotoxic T lymphocytes. | |||
T10565 | BMS-1001 hydrochloride | PD-1/PD-L1 | |
BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activat... | |||
T26637 | Antipain dihydrochloride | Antipain 2HCl,BDBM-32804,BDBM 32804, Antipain,BDBM32804 | Protease |
Antipain dihydrochloride (Antipain 2HCl) is a protease inhibitor derived from Actinomycetes that exhibits analgesic activity and inhibits X-ray-induced chromosomal aberrations in human lymphocytes. | |||
T28918 | Talviraline | Bay 10-8979,HBY 097,Bay10-8979,Bay-108979,Bay108979,Bay 108979,Bay-10-8979 | HIV Protease , DNA/RNA Synthesis |
Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a variety of human cell lines, as well as in fresh human perip... | |||
T6964 | Resiquimod | R848,S28463 | HCV Protease , TLR |
Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and acti... | |||
T16132 | MRE3008F20 | cAMP , Adenosine Receptor | |
MRE3008F20 is a species-selective and potent adenosine A3 receptor (AA3R) antagonist that inhibits Cl-IB-MECA-induced cAMP production and can be used in glaucoma and asthma studies.CAS 번호13483-88-88-9 | |||
T21443 | Prednicarbate | Hoe 777,Hoe-777,Dermatop E emollient,UNII-V901LV1K7D | Others |
Prednicarbate (Hoe 777) is a Corticosteroid Hormone Receptor Agonist. Prednicarbate has antipruritic, anti-inflammatory, and vasoconstrictive properties. It also decreases the number of circulating lymphocytes by inhibit... | |||
T9919 | Alemtuzumab | Others | |
Alemtuzumab is a humanized monoclonal antibody against CD52 an antigen found on the surface of normal and malignant lymphocytes. | |||
T6665 | Sertaconazole nitrate | FI-7045,Ginedermofix,FI7056,Ertaczo | Antibiotic , Antifungal |
Sertaconazole nitrate (FI-7045), a topical broad-spectrum antifungal, is developed to supply an additional agent for the treatment of superficial cutaneous and mucosal infections. | |||
T36879L | H-Leu-Leu-OMe . HBr | H-Leu-Leu-OMe . HBr (16689-14-8 Free base) | Others |
H-Leu-Leu-OMe . HBr is a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes. H-Leu-Leu-OMe . HBr induces endolysosomal pathway stress and selectively eli... | |||
T4387 | Evobrutinib | MSC2364447C,M2951 | BTK |
Evobrutinib(M2951) , also known as M-2951 and MSC-2364447C, is a highly selective inhibitor of the Bruton's tyrosine kinase (BTK), which is important in the development and functioning of various immune cells including B... | |||
T2171 | SEW2871 | SEW2871 | S1P Receptor , LPL Receptor |
SEW 2871 is an orally available, highly selective S1P1 agonist with an EC50 of 13.8 nM.It reduces the number of lymphocytes in the blood and is used in studies related to diabetes, Alzheimer's disease, liver fibrosis, an... | |||
TP1543L | G280-9 acetate(156761-76-1 free base) | Others | |
G280-9 acetate is a common melanoma gp100 epitope restricted by MHC-associated HLA-A2. The G280-9 sequence is unique because it could be recognized by cytotoxic T lymphocytes at very low concentrations, however it shows ... | |||
TP1527 | CEF8, Influenza Virus NP (383-391) | CEF8, Influenza Virus NP 383-391 | Others |
CEF8, Influenza Virus NP (383-391) is an influenza A virus nucleoprotein containing residues 383 to 391, is the most important HLA-B*2705-restricted epitope in the nucleoprotein of influenza A viruses and is associated w... | |||
T4674 | SB297006 | SB 297006 | CCR |
SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of ... | |||
T24362 | L 756423 | L756423,MK-944a,MK944a,L-756,423,L-756423,MK 944a | HIV Protease |
L 756423 (L756423) is a novel potent and selective and competitive HIV protease inhibitor with a Ki value of 0.049 nM for HIV-1 PR.L 756423 blocks the spread of HIV(IIIb)-infected MT25 lymphocytes at 0.50-0.1 nM and can ... | |||
T7055 | Bz-RS-ISer(3-Ph)-Ome | Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate | Others , HIV Protease |
Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle at low cytotoxicity, blocks mitosis in Vero cells, affects the size o... | |||
TQ0291 | Firategrast | SB 683699 | Integrin |
Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity... | |||
T2548 | Diflorasone | Glucocorticoid Receptor | |
Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorti... | |||
T11319 | FR183998 free base | Na+/Ca2+ Exchanger | |
T14909 | CCX140 | CCX140-B | CCR |
CCX140 (CCX140-B) (CCX140-B) is an antagonist of CCR2. | |||
T28408 | Phosphostim Sodium | IPH1101,Phosphostim,IPH 1101,IPH-1101 | |
Phosphostim, a gamma9deta2 T lymphocytes agonist, is used potentially for the treatment of renal cell carcinoma, HCV infection. | |||
T30136 | Armepavine hydrochloride, (+/-)- | DL-Armepavine hydrochloride | |
Armepavine hydrochloride, (+/-)- is a compound which has been shown to exert immunosuppressive effects on T lymphocytes and on lupus nephritic mice. | |||
T70307 | POM2-C-HMBP | ||
POM2-C-HMBP is a potent Activator of Vγ9Vδ2 T-Lymphocytes. It is also an HMBPP ananlog prodrug. | |||
T70889 | Oxeclosporin | ||
Oxeclosporin is a hydroxyethyl derivative of serine(8)-cyclosporine; inhibits proliferation and functions of lymphocytes. | |||
T39145 | 4,6-Dichloroguaiacol | ||
4,6-Dichloroguaiacol elicits biochemical and morphological alterations in human peripheral blood lymphocytes in vitro. | |||
T31018 | CP 115953 | CP115953,Cp-115,953,CP-115953 | |
CP 115953 stimulated the production of cytokines by lymphocytes. CP 115953 inhibits the activity of topoisomerase II by interacting with the enzyme. | |||
T69137 | Oxophenarsine hydrochloride | ||
Oxophenarsine hydrochloride is a classical drug used to treat syphilis. Oxophenarsine HCl inhibits HIV-1-specific protein synthesis in acutely and persistently infected lymphocytes. | |||
T28585 | Ro 31-8588 | Ro-31-8588 | |
Talviraline is a RNA-directed DNA polymerase inhibitor. HBY 097 is a highly potent inhibitor of HIV-1 replication and HIV-1 induced cell killing in a variety of human cell lines as well as in fresh human peripheral bloo... | |||
T9901A-012 | Ibritumomab | ||
Ibritumomab is a murine IgG1k monoclonal antibody, and the complementary-determining region of Ibritumomab binds to CD20 antigen on B lymphocytes. | |||
TP1629 | LCMV gp33-41 (TFA) (151705-84-9 free base) | LCMV gp33-41 (TFA) | |
LCMV gp33-41 (TFA), the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes[1]. | |||
T76835 | Tositumomab | ||
Tositumomab, a murine IgG2a lambda monoclonal antibody, targets the CD20 antigen located on the surface of both normal and malignant B lymphocytes [1]. | |||
T39014 | KSPWFTTL | ||
KSPWFTTL is an immunodominant epitope derived from the p15E transmembrane protein. It is Kb-restricted and can enhance the susceptibility of a tumor cell line to cytotoxic T lymphocytes targeting anti-AKR/Gross MuLV. | |||
T17099 | Timapiprant sodium | OC000459 sodium | Others |
Timapiprant sodium inhibits mast cell activation of Th2 lymphocytes and eosinophils. Timapiprant sodium is a potent and selective D prostanoid receptor 2 antagonist. Timapiprant sodium potently displaces [3H] PGD2 from h... | |||
T37288 | Remisporine B | ||
Remisporine B is a polyketide and derivative of remisporine A that has been found inPenicilliumand has immunosuppressant activity.1,2It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymp... | |||
T35906 | Padanamide A | ||
Padanamide A is a bacterial metabolite originally isolated from a marine Streptomyces species. It is active against five strains of P. falciparum (EC50s = 160-340 nM), is not cytotoxic to HEK293 or HepG2 human cell lines... | |||
T69830 | GSK2239633 | ||
GSK2239633 is a potent CC-chemokine receptor 4 antagonist with pIC50 of 7.9. The CC-chemokine receptor 4 (CCR4) is thought potentially to play a critical role in asthma pathogenesis due to its ability to recruit type 2... | |||
T69723 | Taminadenant mesylate | ||
Taminadenant, also known as PBF-509 and NIR-178, is a potent and orally active adenosine A2A receptor antagonist with potential antineoplastic activity. PBF-509 selectively binds to and inhibits A2AR expressed on T lym... | |||
T82060 | Interleukin-6 fragment (human) | ||
Interleukin-6 Fragment (human) is a pleiotropic cytokine originating from both lymphocytes and non-lymphocytes, encoded by a gene on human chromosome 7 spanning roughly 5 kilobases. This fragment shows promise for use in... | |||
T76755 | Panobacumab | ||
Panobacumab (KBPA101) is a fully human IgM/κ monoclonal antibody developed through the immortalization of human B lymphocytes targeted against the LPS O polysaccharide of P. aeruginosa serotype O11 [1]. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN1697 | Glucosyringic acid | Immunology/Inflammation related | |
Glucosyringic acid has immunosuppressive effect, it can inhibit the proliferation of murine B lymphocytes in vitro. | |||
T7924 | 8-Bromoguanosine | Others | |
8-Bromoguanosine is a brominated derivative of guanosine. It is activate lymphocytes through an intracellular mechanism to exert immunostimulatory effects. | |||
T5S0777 | Phellodendrine chloride | Others | |
Phellodendrine chloride has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli. | |||
T6S0781 | Phellodendrine | Phallodendrin | Others , NF-κB , Akt |
1. Phellodendrine (Phallodendrin) has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli. | |||
T37705 | 1,2,4-Trihydroxybenzene | Benzene-1,2,4-triol | Calcium Channel |
1,2,4-Trihydroxybenzene (Benzene-1,2,4-triol) is a by-product of coffee bean roasting and is found in mouse, arabica coffee.1,2,4-Trihydroxybenzene is a benzotriol that increases Ca2+ concentration in rat thymic lymphocy... | |||
T0798 | Triamcinolone | Fluoxyprednisolone,Aristocort,Rodinolone | Glucocorticoid Receptor , COX |
Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to transloca... | |||
T20879 | Tacrolimus monohydrate | FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506 | Phosphatase , Others , Antibacterial , Antibiotic , Autophagy |
Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, whi... | |||
T4S1943 | Kirenol | Kirel | Wnt/beta-catenin |
1. Kirenol (Kirel) has anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. 2. Kirenol is effective against gram-positive bacteria. 3. Kirenol possesses antitumor action on human chronic myeloid... | |||
TN1861 | Licoflavone C | 4',5,7-Trihydroxy-8-prenylflavone | Antioxidant , Antifungal |
Licoflavone C (4',5,7-Trihydroxy-8-prenylflavone) is an isoprenoid-based flavonoid compound isolated from the roots of Glycyrrhiza inflata, which possesses antioxidant and antifungal activities, and is known to have a pr... | |||
T2563 | Acetyl-L-carnitine hydrochloride | Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride | Others , Endogenous Metabolite |
Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neur... | |||
T13969L | Xanthopterin | Ksantopterin | Others |
Xanthopterin could inhibit the growth of lymphocytes produced by concanavalin. | |||
T70221 | Dibefurin | ||
Dibefurin is a metabolite that inhibits the activity of calcineurin, a calcium/calmodulin-dependent protein phosphatase involved in the activation of T lymphocytes. | |||
T16160 | Musk tibetene | Musk tibetine | Others |
T75502 | Brazilein | ||
Brazilein, an immunosuppressive compound extracted from Caesalpinia sappan L., effectively induces apoptosis in mouse spleen lymphocytes [1]. | |||
TN5138 | Teuclatriol | TNF , NF-κB , TLR | |
Teuclatriol was found to be one of the compounds responsible for the immunoinhibitory effect of Salvia mirzayanii, by inhibiting NF-κB signaling at doses of 312µM and higher. It showed a significant anti-proliferative e... | |||
TN3152 | 6-Acetonyldihydrochelerythrine | ERK , BCL , Akt , HIV Protease , PPAR , p53 | |
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therapeutic Index) values of 1.77 microg/mL and 14.6, respectively... | |||
T75692 | Hypoglaunine D | ||
Hypoglaunine D, an analogue of Triptonine B, serves as an anti-HIV compound by inhibiting HIV replication in H9 lymphocytes, demonstrating an efficacy with an EC50 value of 22 μg/ml [1]. | |||
TN4084 | Fumitremorgin B | Antifection | |
Fumitremorgen B is a mycotoxin, it exhibits a certain degree of genotoxicity, it can cause DNA damage in human lymphocytes; it shows an inhibitory activity on the cell cycle progression of mouse tsFT210 cells in the M ph... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-03956 | Fas Ligand Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells su... | |||
TMPY-04779 | BTN3A2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tu... | |||
TMPY-00817 | Granzyme B/GZMB Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ... | |||
TMPY-00369 | LY6D Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
LY6D (Lymphocyte Antigen 6 Family Member D) is a Protein Coding gene. It may act as a specification marker at the earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of... | |||
TMPJ-01469 | NGF Protein, Human, Recombinant (E. colli) | Mouse | E. coli |
NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family ... | |||
TMPY-02153 | TNF beta Protein, Human, Recombinant | Human | E. coli |
Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lympho... | |||
TMPJ-00994 | LTBR Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including ce... | |||
TMPY-02700 | BCL2 Protein, Human, Recombinant (His) | Human | E. coli |
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a... | |||
TMPK-01494 | HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Cancer/testis antigens 83 (CT83), also called KK-LC-1 or CXorf61, recognized by cytotoxic T lymphocytes (CTL), has become a promising target for immunotherapy. | |||
TMPY-03779 | CCL27 Protein, Human, Recombinant (His) | Human | E. coli |
CCL27, also known as CTACK, is a small cytokine belonging to the CC chemokine family. Members of this family are proteins characterized by two adjacent cysteines. CCL27 is chemotactic for skin-associated memory T lymphoc... | |||
TMPK-01545 | HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ... | |||
TMPK-01514 | HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ... | |||
TMPJ-00824 | Ig lambda constant 2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Immunoglobulin lambda constant region is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recogniti... | |||
TMPY-02795 | Eotaxin-2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in imm... | |||
TMPK-01496 | HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Cancer/testis antigens 83 (CT83), also called KK-LC-1 or CXorf61, recognized by cytotoxic T lymphocytes (CTL), has become a promising target for immunotherapy. | |||
TMPH-01620 | TNF beta Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a w... | |||
TMPK-01544 | HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ... | |||
TMPK-01452 | HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ... | |||
TMPK-01541 | HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ... | |||
TMPH-02176 | Talin-1 Protein, Human, Recombinant (GST) | Human | E. coli |
Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell co... | |||
TMPJ-00223 | SLAMF1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in... | |||
TMPJ-00759 | VDB Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. D... | |||
TMPJ-01341 | CCL24 Protein, Mouse, Recombinant | Mouse | E. coli |
Mouse CCL24 is a secreted protein, which is a member of the CC chemokine subfamily. Mouse Ccl24 cDNA encodes a 119 amino acid residue precursor protein, shares approximately 58% amino acid sequence identity with human Cc... | |||
TMPH-03545 | Enterotoxin type E Protein, S. aureus, Recombinant (His & SUMO) | Staphylococcus aureus | E. coli |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a... | |||
TMPK-01468 | HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Melanoma antigen recognized by T cell-1 (Mart-1), one of the melanosome-specific proteins, also recognized by cytotoxicity T lymphocytes as a marker. Mart-1 is considered to play a critical role in the immunotherapy for ... | |||
TMPK-01469 | HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
Melanoma antigen recognized by T cell-1 (Mart-1), one of the melanosome-specific proteins, also recognized by cytotoxicity T lymphocytes as a marker. Mart-1 is considered to play a critical role in the immunotherapy for ... | |||
TMPK-01269 | CXCL10 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | E. coli |
C-X-C motif ligand 10 (CXCL10), or interferon-inducible protein-10, is a small chemokine belonging to the CXC chemokine family. Its members are responsible for leukocyte trafficking and act on tissue cells, like endothel... | |||
TMPK-00001 | CD24 Protein-VLP, Human, Recombinant | Human | HEK293 Cells |
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo... | |||
TMPJ-00028 | CCL2 Protein, Mouse, Recombinant | Mouse | E. coli |
C-C motif chemokine 2 (CCL2) is a member of the C-C or β chemokine family. Mouse CCL2 shares 82% amino acid (aa) identity with rat CCL2 over the entire sequence, and 58%, 56%, 55%, 53% and 53% aa identity with human, equ... | |||
TMPJ-00110 | GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His) | Mouse | HEK293 Cells |
Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The p... | |||
TMPK-00002 | CD24 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo... | |||
TMPH-02770 | TNF beta Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a w... | |||
TMPJ-00748 | Ig kappa Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Immunoglobulin Kappa is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humor... | |||
TMPH-02451 | IFN gamma Protein, Marmota monax, Recombinant (His) | Marmota monax | P. pastoris (Yeast) |
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproli... | |||
TMPK-00721 | CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 Cells |
Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer... | |||
TMPH-03539 | Enterotoxin type B Protein, S. aureus, Recombinant (His) | Staphylococcus aureus | P. pastoris (Yeast) |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a... | |||
TMPK-00003 | CD24 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo... | |||
TMPK-00005 | CD24 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated | Human | HEK293 Cells |
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo... | |||
TMPH-00373 | IFN gamma Protein, Chicken, Recombinant (GST) | Chicken | E. coli |
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproli... | |||
TMPJ-00008 | CXCL10 Protein, Human, Recombinant (hFc & His) | Human | HEK293 Cells |
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CX... | |||
TMPK-01042 | FcRH6/FCRL6 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Fc receptor-like 6 (FCRL6), the most recently characterized member of the FCRL family, is a cell surface glycoprotein with tyrosine-based regulatory potential. An extensive survey of human hematopoietic tissues disclosed... | |||
TMPH-01654 | MAGEA1 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal developmen... | |||
TMPJ-00532 | PADI4 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyz... | |||
TMPH-02551 | CD20 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium... | |||
TMPK-01318 | CD24 Protein-VLP, Cynomolgus, Recombinant | Cynomolgus | HEK293 Cells |
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo... | |||
TMPK-01278 | CD69 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
CLEC2C (CD69) is a membrane-bound, type II C-lectin receptor and acts as a costimulatory molecule for T cell activation and proliferation. It is involved in lymphocyte proliferation and functions as a signal transmitting... | |||
TMPK-00234 | CD84 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of CD5 B lymphocytes in peripheral blood, lymphoid organs and bone marrow. The main feature of the disease is accumulation of the malignant cells du... | |||
TMPH-03543 | Enterotoxin type C-3 Protein, S. aureus, Recombinant (His & SUMO) | Staphylococcus aureus | E. coli |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a... | |||
TMPH-02500 | AIF-1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage acti... | |||
TMPH-00550 | Epstein-Barr virus (strain B95-8) BCRF1 Protein (His & Myc) | EBV | E. coli |
Plays a role in masking infected cells for immune recognition by cytotoxic T-lymphocytes. Down-regulates the expression of the host TAP1 gene (transporter associated with antigen processing), thereby affecting the transp... | |||
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カタログ番号 | 製品名 | ||
---|---|---|---|
L9420 | Exosome Compound Library | 76 compounds | |
76 exosome-related compounds that can be used for high-throughput and high-content screening. | |||
L4100 | TGF-beta/Smad Compound Library | 184 compounds | |
A unique collection of 184 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening; |