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Search Results for " lymphocytes "

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18

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140

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カタログ番号 製品名 別名 ターゲット
T8527 CPYPP Others
CPYPP is an inhibitor of DOCK2-Rac1 interaction. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner(IC50 : 22.8 µM). CPY...
T3481 Bimolane Topoisomerase
Bimolane is a topoisomerase II inhibitor.
T6403 Siponimod BAF-312 S1P Receptor , LPL Receptor
BAF312 (Siponimod (BAF-312)), a next-generation S1P receptor modulator, is specific for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, respectively. The specificity of BAF312 for S1P1 and S1P5 receptors exhibi...
T23256 RS-25344 hydrochloride PDE
RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor
T6588 Mitoxantrone mitozantrone Topoisomerase , PKC
Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisome...
T10765 Eragidomide CC-90009,Cereblon modulator 1 Apoptosis , Ligand for E3 Ligase , Molecular Glues
Eragidomide (CC-90009; Cereblon modulator 1) is a cereblon (CRBN) E3 ligase modulator. Eragidomide specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.
T7739 L-Leucyl-L-Leucine methyl ester hydrochloride Leu-Leu-ome hydrochloride Others , Endogenous Metabolite
L-Leucyl-L-Leucine methyl ester hydrochloride (Leu-Leu-ome hydrochloride) is a lysosomal condensation product that cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes.
T0158 Mitoxantrone dihydrochloride Mitoxantrone 2HCl,Mitoxantrone hydrochloride,NSC-301739,mitozantrone dihydrochloride Topoisomerase , PKC
Mitoxantrone dihydrochloride (NSC-301739) is the hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. It is a type II topoisomerase inhibitor.
T6933 Peficitinib ASP015K,JNJ-54781532 Tyrosine Kinases , JAK
Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.
T25705 Imupedone LF1695,LF-1695,LF 1695 Others
Imupedone (LF 1695) is a synthetic immunomodulator that modulates T lymphocytes and macrophages, induces T-cell differentiation of bone marrow precursor cells, and increases the proliferative response of lymphocytes to m...
TP1758L LCMV gp33-41 acetate LCMV gp33-41 acetate(151705-84-9 Free base) Others
LCMV gp33-41 acetate is a sequence of lymphocytic choriomeningitis virus which restricted by major histocompatibility complex class I H-2Db and presented to cytotoxic T lymphocytes.
T10565 BMS-1001 hydrochloride PD-1/PD-L1
BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activat...
T26637 Antipain dihydrochloride Antipain 2HCl,BDBM-32804,BDBM 32804, Antipain,BDBM32804 Protease
Antipain dihydrochloride (Antipain 2HCl) is a protease inhibitor derived from Actinomycetes that exhibits analgesic activity and inhibits X-ray-induced chromosomal aberrations in human lymphocytes.
T28918 Talviraline Bay 10-8979,HBY 097,Bay10-8979,Bay-108979,Bay108979,Bay 108979,Bay-10-8979 HIV Protease , DNA/RNA Synthesis
Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a variety of human cell lines, as well as in fresh human perip...
T6964 Resiquimod R848,S28463 HCV Protease , TLR
Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and acti...
T16132 MRE3008F20 cAMP , Adenosine Receptor
MRE3008F20 is a species-selective and potent adenosine A3 receptor (AA3R) antagonist that inhibits Cl-IB-MECA-induced cAMP production and can be used in glaucoma and asthma studies.CAS 번호13483-88-88-9
T21443 Prednicarbate Hoe 777,Hoe-777,Dermatop E emollient,UNII-V901LV1K7D Others
Prednicarbate (Hoe 777) is a Corticosteroid Hormone Receptor Agonist. Prednicarbate has antipruritic, anti-inflammatory, and vasoconstrictive properties. It also decreases the number of circulating lymphocytes by inhibit...
T9919 Alemtuzumab Others
Alemtuzumab is a humanized monoclonal antibody against CD52 an antigen found on the surface of normal and malignant lymphocytes.
T6665 Sertaconazole nitrate FI-7045,Ginedermofix,FI7056,Ertaczo Antibiotic , Antifungal
Sertaconazole nitrate (FI-7045), a topical broad-spectrum antifungal, is developed to supply an additional agent for the treatment of superficial cutaneous and mucosal infections.
T36879L H-Leu-Leu-OMe . HBr H-Leu-Leu-OMe . HBr (16689-14-8 Free base) Others
H-Leu-Leu-OMe . HBr is a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes. H-Leu-Leu-OMe . HBr induces endolysosomal pathway stress and selectively eli...
T4387 Evobrutinib MSC2364447C,M2951 BTK
Evobrutinib(M2951) , also known as M-2951 and MSC-2364447C, is a highly selective inhibitor of the Bruton's tyrosine kinase (BTK), which is important in the development and functioning of various immune cells including B...
T2171 SEW​2871 SEW2871 S1P Receptor , LPL Receptor
SEW 2871 is an orally available, highly selective S1P1 agonist with an EC50 of 13.8 nM.It reduces the number of lymphocytes in the blood and is used in studies related to diabetes, Alzheimer's disease, liver fibrosis, an...
TP1543L G280-9 acetate(156761-76-1 free base) Others
G280-9 acetate is a common melanoma gp100 epitope restricted by MHC-associated HLA-A2. The G280-9 sequence is unique because it could be recognized by cytotoxic T lymphocytes at very low concentrations, however it shows ...
TP1527 CEF8, Influenza Virus NP (383-391) CEF8, Influenza Virus NP 383-391 Others
CEF8, Influenza Virus NP (383-391) is an influenza A virus nucleoprotein containing residues 383 to 391, is the most important HLA-B*2705-restricted epitope in the nucleoprotein of influenza A viruses and is associated w...
T4674 SB297006 SB 297006 CCR
SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of ...
T24362 L 756423 L756423,MK-944a,MK944a,L-756,423,L-756423,MK 944a HIV Protease
L 756423 (L756423) is a novel potent and selective and competitive HIV protease inhibitor with a Ki value of 0.049 nM for HIV-1 PR.L 756423 blocks the spread of HIV(IIIb)-infected MT25 lymphocytes at 0.50-0.1 nM and can ...
T7055 Bz-RS-ISer(3-Ph)-Ome Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate Others , HIV Protease
Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle at low cytotoxicity, blocks mitosis in Vero cells, affects the size o...
TQ0291 Firategrast SB 683699 Integrin
Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity...
T2548 Diflorasone Glucocorticoid Receptor
Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorti...
T11319 FR183998 free base Na+/Ca2+ Exchanger
T14909 CCX140 CCX140-B CCR
CCX140 (CCX140-B) (CCX140-B) is an antagonist of CCR2.
T28408 Phosphostim Sodium IPH1101,Phosphostim,IPH 1101,IPH-1101
Phosphostim, a gamma9deta2 T lymphocytes agonist, is used potentially for the treatment of renal cell carcinoma, HCV infection.
T30136 Armepavine hydrochloride, (+/-)- DL-Armepavine hydrochloride
Armepavine hydrochloride, (+/-)- is a compound which has been shown to exert immunosuppressive effects on T lymphocytes and on lupus nephritic mice.
T70307 POM2-C-HMBP
POM2-C-HMBP is a potent Activator of Vγ9Vδ2 T-Lymphocytes. It is also an HMBPP ananlog prodrug.
T70889 Oxeclosporin
Oxeclosporin is a hydroxyethyl derivative of serine(8)-cyclosporine; inhibits proliferation and functions of lymphocytes.
T39145 4,6-Dichloroguaiacol
4,6-Dichloroguaiacol elicits biochemical and morphological alterations in human peripheral blood lymphocytes in vitro.
T31018 CP 115953 CP115953,Cp-115,953,CP-115953
CP 115953 stimulated the production of cytokines by lymphocytes. CP 115953 inhibits the activity of topoisomerase II by interacting with the enzyme.
T69137 Oxophenarsine hydrochloride
Oxophenarsine hydrochloride is a classical drug used to treat syphilis. Oxophenarsine HCl inhibits HIV-1-specific protein synthesis in acutely and persistently infected lymphocytes.
T28585 Ro 31-8588 Ro-31-8588
Talviraline is a RNA-directed DNA polymerase inhibitor. HBY 097 is a highly potent inhibitor of HIV-1 replication and HIV-1 induced cell killing in a variety of human cell lines as well as in fresh human peripheral bloo...
T9901A-012 Ibritumomab
Ibritumomab is a murine IgG1k monoclonal antibody, and the complementary-determining region of Ibritumomab binds to CD20 antigen on B lymphocytes.
TP1629 LCMV gp33-41 (TFA) (151705-84-9 free base) LCMV gp33-41 (TFA)
LCMV gp33-41 (TFA), the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes[1].
T76835 Tositumomab
Tositumomab, a murine IgG2a lambda monoclonal antibody, targets the CD20 antigen located on the surface of both normal and malignant B lymphocytes [1].
T39014 KSPWFTTL
KSPWFTTL is an immunodominant epitope derived from the p15E transmembrane protein. It is Kb-restricted and can enhance the susceptibility of a tumor cell line to cytotoxic T lymphocytes targeting anti-AKR/Gross MuLV.
T17099 Timapiprant sodium OC000459 sodium Others
Timapiprant sodium inhibits mast cell activation of Th2 lymphocytes and eosinophils. Timapiprant sodium is a potent and selective D prostanoid receptor 2 antagonist. Timapiprant sodium potently displaces [3H] PGD2 from h...
T37288 Remisporine B
Remisporine B is a polyketide and derivative of remisporine A that has been found inPenicilliumand has immunosuppressant activity.1,2It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymp...
T35906 Padanamide A
Padanamide A is a bacterial metabolite originally isolated from a marine Streptomyces species. It is active against five strains of P. falciparum (EC50s = 160-340 nM), is not cytotoxic to HEK293 or HepG2 human cell lines...
T69830 GSK2239633
GSK2239633 is a potent CC-chemokine receptor 4 antagonist with pIC50 of 7.9. The CC-chemokine receptor 4 (CCR4) is thought potentially to play a critical role in asthma pathogenesis due to its ability to recruit type 2...
T69723 Taminadenant mesylate
Taminadenant, also known as PBF-509 and NIR-178, is a potent and orally active adenosine A2A receptor antagonist with potential antineoplastic activity. PBF-509 selectively binds to and inhibits A2AR expressed on T lym...
T82060 Interleukin-6 fragment (human)
Interleukin-6 Fragment (human) is a pleiotropic cytokine originating from both lymphocytes and non-lymphocytes, encoded by a gene on human chromosome 7 spanning roughly 5 kilobases. This fragment shows promise for use in...
T76755 Panobacumab
Panobacumab (KBPA101) is a fully human IgM/κ monoclonal antibody developed through the immortalization of human B lymphocytes targeted against the LPS O polysaccharide of P. aeruginosa serotype O11 [1].

Compounds

CPYPP
T8527
Synonym:
Target: Others
Bimolane
T3481
Synonym:
Target: Topoisomerase
Siponimod
T6403
Synonym: BAF-312
Target: S1P Receptor, LPL Receptor
RS-25344 hydrochloride
T23256
Synonym:
Target: PDE
Mitoxantrone
T6588
Synonym: mitozantrone
Target: Topoisomerase, PKC
Eragidomide
T10765
Synonym: CC-90009,Cereblon modulator 1
Target: Apoptosis, Ligand for E3 Ligase, Molecular Glues
L-Leucyl-L-Leucine methyl ester hydrochloride
T7739
Synonym: Leu-Leu-ome hydrochloride
Target: Others, Endogenous Metabolite
Mitoxantrone dihydrochloride
T0158
Synonym: Mitoxantrone 2HCl,Mitoxantrone hydrochloride,NSC-301739,mitozantrone dihydrochloride
Target: Topoisomerase, PKC
Peficitinib
T6933
Synonym: ASP015K,JNJ-54781532
Target: Tyrosine Kinases, JAK
Imupedone
T25705
Synonym: LF1695,LF-1695,LF 1695
Target: Others
LCMV gp33-41 acetate
TP1758L
Synonym: LCMV gp33-41 acetate(151705-84-9 Free base)
Target: Others
BMS-1001 hydrochloride
T10565
Synonym:
Target: PD-1/PD-L1
Antipain dihydrochloride
T26637
Synonym: Antipain 2HCl,BDBM-32804,BDBM 32804, Antipain,BDBM32804
Target: Protease
Talviraline
T28918
Synonym: Bay 10-8979,HBY 097,Bay10-8979,Bay-108979,Bay108979,Bay 108979,Bay-10-8979
Target: HIV Protease, DNA/RNA Synthesis
Resiquimod
T6964
Synonym: R848,S28463
Target: HCV Protease, TLR
MRE3008F20
T16132
Synonym:
Target: cAMP, Adenosine Receptor
Prednicarbate
T21443
Synonym: Hoe 777,Hoe-777,Dermatop E emollient,UNII-V901LV1K7D
Target: Others
Alemtuzumab
T9919
Synonym:
Target: Others
Sertaconazole nitrate
T6665
Synonym: FI-7045,Ginedermofix,FI7056,Ertaczo
Target: Antibiotic, Antifungal
H-Leu-Leu-OMe . HBr
T36879L
Synonym: H-Leu-Leu-OMe . HBr (16689-14-8 Free base)
Target: Others
evobrutinib
T4387
Synonym: MSC2364447C,M2951
Target: BTK
SEW​2871
T2171
Synonym: SEW2871
Target: S1P Receptor, LPL Receptor
G280-9 acetate(156761-76-1 free base)
TP1543L
Synonym:
Target: Others
CEF8, Influenza Virus NP (383-391)
TP1527
Synonym: CEF8, Influenza Virus NP 383-391
Target: Others
SB297006
T4674
Synonym: SB 297006
Target: CCR
L 756423
T24362
Synonym: L756423,MK-944a,MK944a,L-756,423,L-756423,MK 944a
Target: HIV Protease
Bz-RS-ISer(3-Ph)-Ome
T7055
Synonym: Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate
Target: Others, HIV Protease
Firategrast
TQ0291
Synonym: SB 683699
Target: Integrin
Diflorasone
T2548
Synonym:
Target: Glucocorticoid Receptor
FR183998 free base
T11319
Synonym:
Target: Na+/Ca2+ Exchanger
CCX140
T14909
Synonym: CCX140-B
Target: CCR
Phosphostim Sodium
T28408
Synonym: IPH1101,Phosphostim,IPH 1101,IPH-1101
Target:
Armepavine hydrochloride, (+/-)-
T30136
Synonym: DL-Armepavine hydrochloride
Target:
POM2-C-HMBP
T70307
Synonym:
Target:
Oxeclosporin
T70889
Synonym:
Target:
4,6-Dichloroguaiacol
T39145
Synonym:
Target:
CP 115953
T31018
Synonym: CP115953,Cp-115,953,CP-115953
Target:
Oxophenarsine hydrochloride
T69137
Synonym:
Target:
Ro 31-8588
T28585
Synonym: Ro-31-8588
Target:
Ibritumomab
T9901A-012
Synonym:
Target:
LCMV gp33-41 (TFA) (151705-84-9 free base)
TP1629
Synonym: LCMV gp33-41 (TFA)
Target:
Tositumomab
T76835
Synonym:
Target:
KSPWFTTL
T39014
Synonym:
Target:
Timapiprant sodium
T17099
Synonym: OC000459 sodium
Target: Others
Remisporine B
T37288
Synonym:
Target:
Padanamide A
T35906
Synonym:
Target:
GSK2239633
T69830
Synonym:
Target:
Taminadenant mesylate
T69723
Synonym:
Target:
Interleukin-6 fragment (human)
T82060
Synonym:
Target:
Panobacumab
T76755
Synonym:
Target:
1 2
カタログ番号 製品名 別名 ターゲット
TN1697 Glucosyringic acid Immunology/Inflammation related
Glucosyringic acid has immunosuppressive effect, it can inhibit the proliferation of murine B lymphocytes in vitro.
T7924 8-Bromoguanosine Others
8-Bromoguanosine is a brominated derivative of guanosine. It is activate lymphocytes through an intracellular mechanism to exert immunostimulatory effects.
T5S0777 Phellodendrine chloride Others
Phellodendrine chloride has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.
T6S0781 Phellodendrine Phallodendrin Others , NF-κB , Akt
1. Phellodendrine (Phallodendrin) has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.
T37705 1,2,4-Trihydroxybenzene Benzene-1,2,4-triol Calcium Channel
1,2,4-Trihydroxybenzene (Benzene-1,2,4-triol) is a by-product of coffee bean roasting and is found in mouse, arabica coffee.1,2,4-Trihydroxybenzene is a benzotriol that increases Ca2+ concentration in rat thymic lymphocy...
T0798 Triamcinolone Fluoxyprednisolone,Aristocort,Rodinolone Glucocorticoid Receptor , COX
Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to transloca...
T20879 Tacrolimus monohydrate FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506 Phosphatase , Others , Antibacterial , Antibiotic , Autophagy
Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, whi...
T4S1943 Kirenol Kirel Wnt/beta-catenin
1. Kirenol (Kirel) has anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. 2. Kirenol is effective against gram-positive bacteria. 3. Kirenol possesses antitumor action on human chronic myeloid...
TN1861 Licoflavone C 4',5,7-Trihydroxy-8-prenylflavone Antioxidant , Antifungal
Licoflavone C (4',5,7-Trihydroxy-8-prenylflavone) is an isoprenoid-based flavonoid compound isolated from the roots of Glycyrrhiza inflata, which possesses antioxidant and antifungal activities, and is known to have a pr...
T2563 Acetyl-L-carnitine hydrochloride Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride Others , Endogenous Metabolite
Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neur...
T13969L Xanthopterin Ksantopterin Others
Xanthopterin could inhibit the growth of lymphocytes produced by concanavalin.
T70221 Dibefurin
Dibefurin is a metabolite that inhibits the activity of calcineurin, a calcium/calmodulin-dependent protein phosphatase involved in the activation of T lymphocytes.
T16160 Musk tibetene Musk tibetine Others
T75502 Brazilein
Brazilein, an immunosuppressive compound extracted from Caesalpinia sappan L., effectively induces apoptosis in mouse spleen lymphocytes [1].
TN5138 Teuclatriol TNF , NF-κB , TLR
Teuclatriol was found to be one of the compounds responsible for the immunoinhibitory effect of Salvia mirzayanii, by inhibiting NF-κB signaling at doses of 312µM and higher. It showed a significant anti-proliferative e...
TN3152 6-Acetonyldihydrochelerythrine ERK , BCL , Akt , HIV Protease , PPAR , p53
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therapeutic Index) values of 1.77 microg/mL and 14.6, respectively...
T75692 Hypoglaunine D
Hypoglaunine D, an analogue of Triptonine B, serves as an anti-HIV compound by inhibiting HIV replication in H9 lymphocytes, demonstrating an efficacy with an EC50 value of 22 μg/ml [1].
TN4084 Fumitremorgin B Antifection
Fumitremorgen B is a mycotoxin, it exhibits a certain degree of genotoxicity, it can cause DNA damage in human lymphocytes; it shows an inhibitory activity on the cell cycle progression of mouse tsFT210 cells in the M ph...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-03956 Fas Ligand Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells su...
TMPY-04779 BTN3A2 Protein, Human, Recombinant (His) Human HEK293 Cells
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tu...
TMPY-00817 Granzyme B/GZMB Protein, Human, Recombinant (His) Human HEK293 Cells
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ...
TMPY-00369 LY6D Protein, Human, Recombinant (mFc) Human HEK293 Cells
LY6D (Lymphocyte Antigen 6 Family Member D) is a Protein Coding gene. It may act as a specification marker at the earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of...
TMPJ-01469 NGF Protein, Human, Recombinant (E. colli) Mouse E. coli
NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family ...
TMPY-02153 TNF beta Protein, Human, Recombinant Human E. coli
Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lympho...
TMPJ-00994 LTBR Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including ce...
TMPY-02700 BCL2 Protein, Human, Recombinant (His) Human E. coli
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a...
TMPK-01494 HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Cancer/testis antigens 83 (CT83), also called KK-LC-1 or CXorf61, recognized by cytotoxic T lymphocytes (CTL), has become a promising target for immunotherapy.
TMPY-03779 CCL27 Protein, Human, Recombinant (His) Human E. coli
CCL27, also known as CTACK, is a small cytokine belonging to the CC chemokine family. Members of this family are proteins characterized by two adjacent cysteines. CCL27 is chemotactic for skin-associated memory T lymphoc...
TMPK-01545 HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPK-01514 HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPJ-00824 Ig lambda constant 2 Protein, Human, Recombinant (His) Human HEK293 Cells
Immunoglobulin lambda constant region is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recogniti...
TMPY-02795 Eotaxin-2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in imm...
TMPK-01496 HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Cancer/testis antigens 83 (CT83), also called KK-LC-1 or CXorf61, recognized by cytotoxic T lymphocytes (CTL), has become a promising target for immunotherapy.
TMPH-01620 TNF beta Protein, Human, Recombinant (His) Human HEK293 Cells
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a w...
TMPK-01544 HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPK-01452 HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi) Human HEK293 Cells
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPK-01541 HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with ...
TMPH-02176 Talin-1 Protein, Human, Recombinant (GST) Human E. coli
Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell co...
TMPJ-00223 SLAMF1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in...
TMPJ-00759 VDB Protein, Human, Recombinant (His) Human HEK293 Cells
Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. D...
TMPJ-01341 CCL24 Protein, Mouse, Recombinant Mouse E. coli
Mouse CCL24 is a secreted protein, which is a member of the CC chemokine subfamily. Mouse Ccl24 cDNA encodes a 119 amino acid residue precursor protein, shares approximately 58% amino acid sequence identity with human Cc...
TMPH-03545 Enterotoxin type E Protein, S. aureus, Recombinant (His & SUMO) Staphylococcus aureus E. coli
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPK-01468 HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Melanoma antigen recognized by T cell-1 (Mart-1), one of the melanosome-specific proteins, also recognized by cytotoxicity T lymphocytes as a marker. Mart-1 is considered to play a critical role in the immunotherapy for ...
TMPK-01469 HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Melanoma antigen recognized by T cell-1 (Mart-1), one of the melanosome-specific proteins, also recognized by cytotoxicity T lymphocytes as a marker. Mart-1 is considered to play a critical role in the immunotherapy for ...
TMPK-01269 CXCL10 Protein, Cynomolgus, Recombinant (His) Cynomolgus E. coli
C-X-C motif ligand 10 (CXCL10), or interferon-inducible protein-10, is a small chemokine belonging to the CXC chemokine family. Its members are responsible for leukocyte trafficking and act on tissue cells, like endothel...
TMPK-00001 CD24 Protein-VLP, Human, Recombinant Human HEK293 Cells
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPJ-00028 CCL2 Protein, Mouse, Recombinant Mouse E. coli
C-C motif chemokine 2 (CCL2) is a member of the C-C or β chemokine family. Mouse CCL2 shares 82% amino acid (aa) identity with rat CCL2 over the entire sequence, and 58%, 56%, 55%, 53% and 53% aa identity with human, equ...
TMPJ-00110 GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His) Mouse HEK293 Cells
Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The p...
TMPK-00002 CD24 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPH-02770 TNF beta Protein, Mouse, Recombinant (His) Mouse E. coli
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a w...
TMPJ-00748 Ig kappa Protein, Human, Recombinant (His) Human HEK293 Cells
Immunoglobulin Kappa is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humor...
TMPH-02451 IFN gamma Protein, Marmota monax, Recombinant (His) Marmota monax P. pastoris (Yeast)
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproli...
TMPK-00721 CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293 Cells
Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer...
TMPH-03539 Enterotoxin type B Protein, S. aureus, Recombinant (His) Staphylococcus aureus P. pastoris (Yeast)
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPK-00003 CD24 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPK-00005 CD24 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated Human HEK293 Cells
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPH-00373 IFN gamma Protein, Chicken, Recombinant (GST) Chicken E. coli
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproli...
TMPJ-00008 CXCL10 Protein, Human, Recombinant (hFc & His) Human HEK293 Cells
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CX...
TMPK-01042 FcRH6/FCRL6 Protein, Human, Recombinant (His) Human HEK293 Cells
Fc receptor-like 6 (FCRL6), the most recently characterized member of the FCRL family, is a cell surface glycoprotein with tyrosine-based regulatory potential. An extensive survey of human hematopoietic tissues disclosed...
TMPH-01654 MAGEA1 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal developmen...
TMPJ-00532 PADI4 Protein, Human, Recombinant (E. coli, His) Human E. coli
Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyz...
TMPH-02551 CD20 Protein, Mouse, Recombinant (His) Mouse P. pastoris (Yeast)
B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium...
TMPK-01318 CD24 Protein-VLP, Cynomolgus, Recombinant Cynomolgus HEK293 Cells
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPK-01278 CD69 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
CLEC2C (CD69) is a membrane-bound, type II C-lectin receptor and acts as a costimulatory molecule for T cell activation and proliferation. It is involved in lymphocyte proliferation and functions as a signal transmitting...
TMPK-00234 CD84 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of CD5 B lymphocytes in peripheral blood, lymphoid organs and bone marrow. The main feature of the disease is accumulation of the malignant cells du...
TMPH-03543 Enterotoxin type C-3 Protein, S. aureus, Recombinant (His & SUMO) Staphylococcus aureus E. coli
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPH-02500 AIF-1 Protein, Mouse, Recombinant (His) Mouse E. coli
Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage acti...
TMPH-00550 Epstein-Barr virus (strain B95-8) BCRF1 Protein (His & Myc) EBV E. coli
Plays a role in masking infected cells for immune recognition by cytotoxic T-lymphocytes. Down-regulates the expression of the host TAP1 gene (transporter associated with antigen processing), thereby affecting the transp...
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Fas Ligand Protein, Human, Recombinant (His)
TMPY-03956
Species: Human
Expression System: P. pastoris (Yeast)
BTN3A2 Protein, Human, Recombinant (His)
TMPY-04779
Species: Human
Expression System: HEK293 Cells
Granzyme B/GZMB Protein, Human, Recombinant (His)
TMPY-00817
Species: Human
Expression System: HEK293 Cells
LY6D Protein, Human, Recombinant (mFc)
TMPY-00369
Species: Human
Expression System: HEK293 Cells
NGF Protein, Human, Recombinant (E. colli)
TMPJ-01469
Species: Mouse
Expression System: E. coli
TNF beta Protein, Human, Recombinant
TMPY-02153
Species: Human
Expression System: E. coli
LTBR Protein, Mouse, Recombinant (hFc)
TMPJ-00994
Species: Mouse
Expression System: HEK293 Cells
BCL2 Protein, Human, Recombinant (His)
TMPY-02700
Species: Human
Expression System: E. coli
HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01494
Species: Human
Expression System: HEK293 Cells
CCL27 Protein, Human, Recombinant (His)
TMPY-03779
Species: Human
Expression System: E. coli
HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01545
Species: Human
Expression System: HEK293 Cells
HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi)
TMPK-01514
Species: Human
Expression System: HEK293 Cells
Ig lambda constant 2 Protein, Human, Recombinant (His)
TMPJ-00824
Species: Human
Expression System: HEK293 Cells
Eotaxin-2 Protein, Human, Recombinant (His)
TMPY-02795
Species: Human
Expression System: Baculovirus Insect Cells
HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Monomer Protein, Human, MHC (His & Avi)
TMPK-01496
Species: Human
Expression System: HEK293 Cells
TNF beta Protein, Human, Recombinant (His)
TMPH-01620
Species: Human
Expression System: HEK293 Cells
HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01544
Species: Human
Expression System: HEK293 Cells
HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi)
TMPK-01452
Species: Human
Expression System: HEK293 Cells
HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01541
Species: Human
Expression System: HEK293 Cells
Talin-1 Protein, Human, Recombinant (GST)
TMPH-02176
Species: Human
Expression System: E. coli
SLAMF1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00223
Species: Human
Expression System: HEK293 Cells
VDB Protein, Human, Recombinant (His)
TMPJ-00759
Species: Human
Expression System: HEK293 Cells
CCL24 Protein, Mouse, Recombinant
TMPJ-01341
Species: Mouse
Expression System: E. coli
Enterotoxin type E Protein, S. aureus, Recombinant (His & SUMO)
TMPH-03545
Species: Staphylococcus aureus
Expression System: E. coli
HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01468
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Monomer Protein, Human, MHC (His & Avi)
TMPK-01469
Species: Human
Expression System: HEK293 Cells
CXCL10 Protein, Cynomolgus, Recombinant (His)
TMPK-01269
Species: Cynomolgus
Expression System: E. coli
CD24 Protein-VLP, Human, Recombinant
TMPK-00001
Species: Human
Expression System: HEK293 Cells
CCL2 Protein, Mouse, Recombinant
TMPJ-00028
Species: Mouse
Expression System: E. coli
GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His)
TMPJ-00110
Species: Mouse
Expression System: HEK293 Cells
CD24 Protein, Human, Recombinant (His & Avi)
TMPK-00002
Species: Human
Expression System: HEK293 Cells
TNF beta Protein, Mouse, Recombinant (His)
TMPH-02770
Species: Mouse
Expression System: E. coli
Ig kappa Protein, Human, Recombinant (His)
TMPJ-00748
Species: Human
Expression System: HEK293 Cells
IFN gamma Protein, Marmota monax, Recombinant (His)
TMPH-02451
Species: Marmota monax
Expression System: P. pastoris (Yeast)
CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-00721
Species: Mouse
Expression System: HEK293 Cells
Enterotoxin type B Protein, S. aureus, Recombinant (His)
TMPH-03539
Species: Staphylococcus aureus
Expression System: P. pastoris (Yeast)
CD24 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00003
Species: Human
Expression System: HEK293 Cells
CD24 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
TMPK-00005
Species: Human
Expression System: HEK293 Cells
IFN gamma Protein, Chicken, Recombinant (GST)
TMPH-00373
Species: Chicken
Expression System: E. coli
CXCL10 Protein, Human, Recombinant (hFc & His)
TMPJ-00008
Species: Human
Expression System: HEK293 Cells
FcRH6/FCRL6 Protein, Human, Recombinant (His)
TMPK-01042
Species: Human
Expression System: HEK293 Cells
MAGEA1 Protein, Human, Recombinant (His)
TMPH-01654
Species: Human
Expression System: P. pastoris (Yeast)
PADI4 Protein, Human, Recombinant (E. coli, His)
TMPJ-00532
Species: Human
Expression System: E. coli
CD20 Protein, Mouse, Recombinant (His)
TMPH-02551
Species: Mouse
Expression System: P. pastoris (Yeast)
CD24 Protein-VLP, Cynomolgus, Recombinant
TMPK-01318
Species: Cynomolgus
Expression System: HEK293 Cells
CD69 Protein, Cynomolgus, Recombinant (His)
TMPK-01278
Species: Cynomolgus
Expression System: HEK293 Cells
CD84 Protein, Human, Recombinant (His & Avi)
TMPK-00234
Species: Human
Expression System: HEK293 Cells
Enterotoxin type C-3 Protein, S. aureus, Recombinant (His & SUMO)
TMPH-03543
Species: Staphylococcus aureus
Expression System: E. coli
AIF-1 Protein, Mouse, Recombinant (His)
TMPH-02500
Species: Mouse
Expression System: E. coli
Epstein-Barr virus (strain B95-8) BCRF1 Protein (His & Myc)
TMPH-00550
Species: EBV
Expression System: E. coli
カタログ番号 製品名
L9420 Exosome Compound Library

76 compounds
76 exosome-related compounds that can be used for high-throughput and high-content screening.
L4100 TGF-beta/Smad Compound Library

184 compounds
A unique collection of 184 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;