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天然化合物

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カタログ番号	製品名	別名	ターゲット
T60026	KIF18A-IN-2		Microtubule Associated
	KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.		Microtubule Associated
T9595	LP-261		Microtubule Associated
	LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.		Microtubule Associated
T8492	BO-264		Apoptosis , FGFR
	BO-264 is a highly potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3, IC50 of 188 nM and a Kd of 1.5 nM).		Apoptosis , FGFR
T9521	CHR-6494 TFA		Others
	CHR-6494 TFA is a potent haspin inhibitor, with an IC50 of 2 nM. It inhibits histone H3T3 phosphorylation. CHR-6494 TFA induces the apoptosis of cancer cells, including melanoma and breast cancer. CHR-6494 TFA can be use...		Others
TQ0317	R1530	R-1530,R 1530	VEGFR , FGFR , FLT , PDGFR
	R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.		VEGFR , FGFR , FLT , PDGFR
T8342	BRD9876		Others , Kinesin , Microtubule Associated
	BRD9876 is a selective inhibitor of MM1S growth.		Others , Kinesin , Microtubule Associated
T16156	MT 63-78		Apoptosis , AMPK , mTOR
	MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM). MT 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mTORC1 pathways. MT 63-78 has antitumor effects. MT 63–78 also causes cel...		Apoptosis , AMPK , mTOR
T6019	Volasertib	BI 6727	Apoptosis , PLK
	Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis. It also inhibits PLK2/PLK3 (IC50s: 5/56 nM).		Apoptosis , PLK
T9083	TC11	CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11	BCL , Caspase , CDK
	TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis via activation of caspase-3, 8 and 9.		BCL , Caspase , CDK
T2241	Alisertib	MLN 8237	Apoptosis , Aurora Kinase , Autophagy
	Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.		Apoptosis , Aurora Kinase , Autophagy
T6393	ARQ 621		Kinesin
	ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.		Kinesin
T3330L	Cis-trismethoxy Resveratrol	(Z)-3,5,4'-Trimethoxystilbene	Microtubule Associated
	cis-trismethoxy Resveratrol ((Z)-3,5,4'-Trimethoxystilbene) inhibits tubulin polymerization (IC50 = 4 μM) and has anti-mitotic effects.		Microtubule Associated
T4029	BTB-1	BTB 1,NSC156750	Microtubule Associated
	BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.		Microtubule Associated
T20506	Maleuric acid	N-Carbamoylmaleamic acid,AI3 32778,AI3-32778,AI332778	Others
	Maleuric acid (N-Carbamoylmaleamic acid) is anti-mitotic and can be used in biological research in conjunction with radioautography.Maleuric acid is used to improve the growth and fertility of plants and animals as well ...		Others
T4048	Monastrol	(±)-Monastrol	Apoptosis , Kinesin
	Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.		Apoptosis , Kinesin
T3120	K858 (Racemic)	K858 Racemic,K858	Apoptosis , Kinesin
	K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.		Apoptosis , Kinesin
T15576	Indibulin	ZIO 301,D 24851	Apoptosis , Microtubule Associated
	Indibulin (D 24851) is a synthetic small molecule with antimitotic and potential antineoplastic activities.Indibulin an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neu...		Apoptosis , Microtubule Associated
T18867	Val-Cit-PAB-MMAE
	Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE . MMAE a potent mitotic inhibitor by inhibiting tubulin polymerizat...
T16391	ON-013100		CDK
	ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.		CDK
T11383	GDP366		Survivin
			Survivin
T36816	S-trityl-L-Cysteine	STLC	Kinesin
	S-trityl-L-Cysteine is a non-natural amino acid and an inhibitor of Eg5, also known as KSP and Kif11, a mitotic kinesin necessary for mitotic spindle formation. S-trityl-L-Cysteine inhibits the ATPase activity of Eg5 in ...		Kinesin
T67935	Tubulin inhibitor 11		Apoptosis , Microtubule Associated
	Tubulin Inhibitor 11 is a potent, orally active agent that inhibits tubulin by targeting the Colchicine binding site. It impedes tubulin polymerization, leading to mitotic blockade and apoptosis.		Apoptosis , Microtubule Associated
T2440	IC261	SU-5607	Apoptosis , Casein Kinase , CDK
	IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.		Apoptosis , Casein Kinase , CDK
T9831	MKC-1	Ro-31-7453	Apoptosis , Akt , Microtubule Associated , mTOR
	MKC-1 (Ro-31-7453) is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the format...		Apoptosis , Akt , Microtubule Associated , mTOR
T61184	LQZ-7F		Apoptosis , Survivin
	LQZ-7F is a small molecule survivin dimerisation inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation, mitotic arrest, and apoptosis, and blocks human tumour growth in mouse xenogra...		Apoptosis , Survivin
T16987	TAO Kinase inhibitor 1		Others , MAPK
	TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death. TAO Kinase inhibitor 1 is a selective and ATP-competitive thousand-and-one amino acid kinases inhibitor (IC50s: 11 to 15 nM for TAOK1 and 2, respectiv...		Others , MAPK
T0500	Chloroxine	Capitrol	Antibacterial , Antibiotic
	Chloroxine (Capitrol) is a synthetic quinoline derivative with antibacterial activity. Although the mechanism of action is not fully understood, topical administration of chloroxine diminishes mitotic activity in the epi...		Antibacterial , Antibiotic
T2511	Plinabulin	NPI-2358	Microtubule Associated
	Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM). Plinabulin selectively targets and binds to the colchicine-binding site of tubulin, the...		Microtubule Associated
T36674	DMU-212		Apoptosis , ERK
	DMU-212 is a methylated derivative of Resveratrol , with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2...		Apoptosis , ERK
T2090	Lexibulin	CYT-997	Apoptosis , Reactive Oxygen Species , Microtubule Associated
	Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines). Lexibulin blocks the formation of the mitotic spindle and leading to cell cycle arrest at the G2/M phase; this...
T10215	AAPK-25		Apoptosis , PLK , Aurora Kinase
			Apoptosis , PLK , Aurora Kinase
T9657	FiVe1		Others
	FiVe1 is a vimentin binding small molecule that promotes the disintegration and phosphorylation of vimentin in the metaphase, leading to mitotic disasters, polynuclearization, and loss of cancer cell dryness. FiVe1 selec...		Others
T21678	3MB-PP1		PLK
	3MB-PP1 is a bulky purine analog and a Polo-like kinase 1 (Plk1) inhibitor. In cells expressing analog-sensitive Plk1 alleles, 3MB-PP1 blocks mitotic progression and cell division arise by targeting Plk1. 3MB-PP1 specifi...		PLK
T34787	TAS-119	TAS119,TAS2104,TAS 2104,TAS-2104,TAS 119	Aurora Kinase
			Aurora Kinase
T77651	Tubulin polymerization-IN-47		Microtubule Associated
	Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancer cell proliferation, with IC50s of 7 and 12 nM for Chp-134 an...		Microtubule Associated
T8561	Apcin		APC
	Apcin is a potent and competitive inhibitor of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substr...		APC
T19661	8-Chloroadenosine	NSC 354258,8-Cl-Ado,NSC354258,NSC-354258	AMPK
	8-Chloroadenosine (NSC-354258) is a 5' AMP-activated protein kinase agonist potentially for the treatment of chronic lymphocytic leukemia. 8-chloroadenosine activity is associated with inhibition of the mTOR pathway.8-Ch...		AMPK
T69433	Myrmicacin
	Myrmicacin is an inhibitor of mitotic progression after metaphase.
T30308	BDPSB
	BDPSB is a highly efficient photocontroller of mitotic kinesin Eg5 ATPase activity.
T10948	MMAE-d8	D8-MMAE,D8-Monomethyl auristatin E	Others
	D8-MMAE (D8-Monomethyl auristatin E) is an effective mitotic inhibitor and tubulin inhibitor, deuterated MMAE.		Others
T71584	Microtubule Inhibitor 185322
	Microtubule inhibitor 185322 is an inhibitor of microtubule assembly, inducung mitotic arrest and apoptosis of MM cells.
T71609	Hexestrol diphosphate sodium
	Hexestrol diphosphate sodium is a synthetic ER agonist, microtubule polymerization inhibitor, and potential carcinogen. It induces mitotic arrest, aneuploidy, and DNA adduct formation.
T24150	HR22C16	HR-22-C-16,HR 22 C 16
	HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.
T29101	VE-465
	VE-465 is an inhibitor of Aurora kinase, which involves in multiple mitotic events.
T4649	(S)-Monastrol		Kinesin
	(S)-Monastroll is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.		Kinesin
T29233	Z-LLNle-CHO
	Z-LLNle-CHO is a cell permeable inhibitor of gamma-secretase. Z-LLNle-CHO induces apoptosis of human glioblastoma tumor-initiating cells by proteasome inhibition and mitotic arrest response.
T14906	CCT251455		Kinesin
	CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).		Kinesin
T70114	Paclitaxel Ceribate
	Paclitaxel Ceribate is a mitotic inhibitor used in cancer chemotherapy.
TQ0314	EMD534085		Kinesin
			Kinesin
T33411	Mitopodozide	SP-I 77,SPI 77,SPI-77
	Mitopodozide, as an ethylhydrazide derivative of podophyllic acid, acts as a mitotic poison in carcinomas of the ovary.

Compounds

KIF18A-IN-2

T60026

Synonym:

Target: Microtubule Associated

LP-261

T9595

Synonym:

Target: Microtubule Associated

BO-264

T8492

Synonym:

Target: Apoptosis, FGFR

Synonym: R-1530,R 1530

Target: VEGFR, FGFR, FLT, PDGFR

BRD9876

T8342

Synonym:

Target: Others, Kinesin, Microtubule Associated

MT 63-78

T16156

Synonym:

Target: Apoptosis, AMPK, mTOR

Volasertib

T6019

Synonym: BI 6727

Target: Apoptosis, PLK

TC11

T9083

Synonym: CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11

Target: BCL, Caspase, CDK

Alisertib

T2241

Synonym: MLN 8237

Target: Apoptosis, Aurora Kinase, Autophagy

cis-trismethoxy Resveratrol

T3330L

Synonym: (Z)-3,5,4'-Trimethoxystilbene

Target: Microtubule Associated

BTB-1

T4029

Synonym: BTB 1,NSC156750

Target: Microtubule Associated

Maleuric acid

T20506

Synonym: N-Carbamoylmaleamic acid,AI3 32778,AI3-32778,AI332778

Target: Others

Monastrol

T4048

Synonym: (±)-Monastrol

Target: Apoptosis, Kinesin

K858 (Racemic)

T3120

Synonym: K858 Racemic,K858

Target: Apoptosis, Kinesin

Indibulin

T15576

Synonym: ZIO 301,D 24851

Target: Apoptosis, Microtubule Associated

Target: Apoptosis, Microtubule Associated

IC261

T2440

Synonym: SU-5607

Target: Apoptosis, Casein Kinase, CDK

MKC-1

T9831

Synonym: Ro-31-7453

Target: Apoptosis, Akt, Microtubule Associated, mTOR

LQZ-7F

T61184

Synonym:

Target: Apoptosis, Survivin

TAO Kinase inhibitor 1

Target: Antibacterial, Antibiotic

Plinabulin

T2511

Synonym: NPI-2358

Target: Microtubule Associated

DMU-212

T36674

Synonym:

Target: Apoptosis, ERK

Lexibulin

T2090

Synonym: CYT-997

Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated

AAPK-25

T10215

Synonym:

Target: Apoptosis, PLK, Aurora Kinase

Synonym: TAS119,TAS2104,TAS 2104,TAS-2104,TAS 119

Target: Aurora Kinase

Tubulin polymerization-IN-47

T77651

Synonym:

Target: Microtubule Associated

Synonym: NSC 354258,8-Cl-Ado,NSC354258,NSC-354258

Synonym: D8-MMAE,D8-Monomethyl auristatin E

Target: Others

Microtubule Inhibitor 185322

T71584

Synonym:

Target:

Hexestrol diphosphate sodium

Synonym: HR-22-C-16,HR 22 C 16

Synonym: SP-I 77,SPI 77,SPI-77

Target:

カタログ番号	製品名	別名	ターゲット
TN7041	(-)-Epipodophyllotoxin		Apoptosis
	(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells with GI50s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vit...		Apoptosis
TN2190	Scoulerine		Apoptosis , Beta-Secretase , BACE , Parasite
	Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1). Scoulerine a potent antimitotic compound that inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells.		Apoptosis , Beta-Secretase , BACE , Parasite
T21351	Maytansine	NSC-153858,NSC153858,Maitansina,NSC 153858,Maitansine	Microtubule Associated , Antibiotic
	Maytansine (NSC-153858), an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.		Microtubule Associated , Antibiotic
T19720	Colcemid	C 12669,C-12669,NSC-3096,Kolchicin,C12669,Demecolcine	Microtubule Associated
	Colcemid (NSC-3096) is an inhibitor of microtubule polymerization. It used to study embryonic cloning.		Microtubule Associated
T22455	Vindesine sulfate	DVA,Desacetylvinblastine amide,DAVA,Desacetyl Vinblastine amide,VDS	Others
	Vindesine sulfate (Desacetyl Vinblastine amide) is a vinca alkaloid which is a synthetic derivative of vinblastine, binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule...		Others
T1270	Vincristine sulfate	Leurocristine,22-Oxovincaleukoblastine sulfate,Leurocristine sulfate	Apoptosis , Microtubule Associated
	Vincristine sulfate (Leurocristine sulfate) binds irreversibly to microtubules and spindle proteins in S phase and interferes the formation of the mitotic spindle.		Apoptosis , Microtubule Associated
T14304	Aphidicolin		Others
	Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus[2]. It targets D...		Others
T0190	Vinorelbine	KW-2307 base	Microtubule Associated
	Vinorelbine (KW-2307 base) is a semisynthetic vinca alkaloid. Vinorelbine binds to tubulin and prevents the formation of the mitotic spindle, resulting in the arrest of tumor cell growth in metaphase.		Microtubule Associated
T0968	Paclitaxel	Taxol,NSC 125973	Apoptosis , Microtubule Associated , Autophagy
	Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.		Apoptosis , Microtubule Associated , Autophagy
T6213	Vinorelbine ditartrate	Vinorelbine Tartrate,Nor-5'-anhydrovinblastine ditartrate,KW-2307,Navelbine tartrate	Microtubule Associated , Autophagy
	Vinorelbine ditartrate (KW-2307), a semi-synthetic vinca alkaloid, interacts with tubulin resulting in mitosis inhibition.		Microtubule Associated , Autophagy
T6718	Zingerone	Gingerone,Vanillylacetone,NSC 15335	NF-κB
	Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antidiarrhoeic, antilipolytic, antispasmodic and anti-tumor properties. Zingerone(Gi...		NF-κB
T64353	4-tert-Octylphenol		Endogenous Metabolite
	4-tert-Octylphenol, an endocrine-disrupting chemical with estrogenic properties, notably induces apoptosis in offspring mouse brain neuronal progenitor cells. This compound decreases levels of bromodeoxyuridine (BrdU), m...		Endogenous Metabolite
TMM2618	Gibberllin A7	Gibberellin A7,Gibberllin 7	Others
	Gibberllin A7 (Gibberllin 7) is important plant growth hormones that promote plant cell growth and elongation. Gebberillins promote rapid stem and root growth, induce mitotic division and initiate (break dormancy) and in...		Others
T32055	Hemiasterlin	NSC 695242,NSC-695242,Milnamide B,NSC695242,(-)-Hemiasterlin
	Hemiasterlin is a cytotoxic peptide that acts by inducing mitotic arrest and abnormal spindle formation.
TQ0112	Tubulysin A	TubA	Microtubule Associated
	Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, and anti-angiogenic.		Microtubule Associated
T75576	Solidagonic acid
	Solidagonic acid, by inhibiting HSET motor activity, promotes the conversion of abnormal monopolar spindles to bipolar configurations, effectively suppressing fission yeast cell death and facilitating the mitotic spindle...

天然物製品

(-)-Epipodophyllotoxin

Target: Apoptosis, Beta-Secretase, BACE, Parasite

Maytansine

T21351

Synonym: NSC-153858,NSC153858,Maitansina,NSC 153858,Maitansine

Target: Microtubule Associated, Antibiotic

Colcemid

T19720

Synonym: C 12669,C-12669,NSC-3096,Kolchicin,C12669,Demecolcine

Target: Microtubule Associated

Vindesine sulfate

T22455

Synonym: DVA,Desacetylvinblastine amide,DAVA,Desacetyl Vinblastine amide,VDS

Target: Others

Vincristine sulfate

T1270

Synonym: Leurocristine,22-Oxovincaleukoblastine sulfate,Leurocristine sulfate

Target: Apoptosis, Microtubule Associated

Synonym: KW-2307 base

Target: Microtubule Associated

Paclitaxel

T0968

Synonym: Taxol,NSC 125973

Target: Apoptosis, Microtubule Associated, Autophagy

Vinorelbine ditartrate

T6213

Synonym: Vinorelbine Tartrate,Nor-5'-anhydrovinblastine ditartrate,KW-2307,Navelbine tartrate

Target: Microtubule Associated, Autophagy

Zingerone

T6718

Synonym: Gingerone,Vanillylacetone,NSC 15335

Target: Endogenous Metabolite

Gibberllin A7

TMM2618

Synonym: Gibberellin A7,Gibberllin 7

Target: Others

Hemiasterlin

T32055

Synonym: NSC 695242,NSC-695242,Milnamide B,NSC695242,(-)-Hemiasterlin

Target: Microtubule Associated

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02238	MAD2L1 Protein, Human, Recombinant (His)	Human	E. coli
	Mitotic spindle assembly checkpoint protein MAD2A, also known as HsMAD2, Mitotic arrest deficient 2-like protein 1, MAD2-like protein 1, MAD2L1, and MAD2, is a nucleus and cytoplasm protein that belongs to the MAD2 famil...
TMPY-04125	PTP1B Protein, Human, Recombinant (His)	Human	E. coli
	PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c...
TMPH-01592	KIF18B Protein, Human, Recombinant (His & Myc)	Human	E. coli
	In complex with KIF2C, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Its major role may be to transport KIF2C and/or MAPRE1 along microtubules.
TMPY-04025	CEP57 Protein, Human, Recombinant (GST)	Human	E. coli
	CEP57 is a centrosomal protein and is involved in nucleating and stabilizing microtubules. CEP57 was initially identified as a regulator of centriole overduplication in an RNA interference screen. There is a link between...
TMPH-01704	RAE1 Protein, Human, Recombinant (GST)	Human	E. coli
	Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. RAE1 Protein, Human, Recombinant (...
TMPH-01081	CHMP7 Protein, Human, Recombinant (His)	Human	E. coli
	ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase. Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly ...
TMPH-03438	CHS1 Protein, S. cerevisiae, Recombinant (His)	Saccharomyces cerevisiae	E. coli
	Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. Required for mitotic division septum formation d...
TMPK-00618	FcRH5/FcRL5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),...
TMPH-01703	CDC25C Protein, Human, Recombinant (His)	Human	E. coli
	Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly de...
TMPK-01039	FcRH5/FcRL5 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),...
TMPK-01145	FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),...
TMPK-00619	FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),...
TMPY-04558	NEK7 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	NIMA (never in mitosis gene a)-related kinase 7, NEK7 belongs to the NIMA subfamily, NEK Ser/Thr protein kinase family, protein kinase superfamily. NEKs (NIMA-related kinases) are mammalian serine/threonine (Ser/Thr) pro...
TMPH-02884	CTDP1 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit...
TMPY-03442	MOB4A/MOB1B Protein, Human, Recombinant (GST)	Human	E. coli
	MST1 and MST2 are the mammalian Ste2-related protein kinases most closely related to Drosophila Hippo, a major regulator of cell proliferation and survival during development. Overexpression of MST1 or MST2 in mammalian ...
TMPH-02304	Vasohibin-2/VASH2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mito...
TMPJ-00465	PTP1C Protein, Human, Recombinant (His)	Human	E. coli
	Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mi...
TMPJ-01436	MKI67 Protein, Human, Recombinant (GST)	Human	E. coli
	MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferatio...
TMPJ-00972	CDKN1B Protein, Human, Recombinant (His)	Human	E. coli
	Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B) is a Kinesin-related motor protein necessary for mitotic spindle assembly and chromosome segregation. CDKN1B is expressed in all tissues with highest levels observed in skele...
TMPY-03296	SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST)	Mouse	Baculovirus Insect Cells
	PTPN6 is an enzyme that belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and onco...
TMPJ-00960	TMPO Protein, Human, Recombinant (His)	Human	E. coli
	Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domai...
TMPH-00536	Epstein-Barr virus (strain AG876) EBNA2 Protein (His & Myc)	EBV	P. pastoris (Yeast)
	Plays a key role in the activation of the host resting B-cell and stimulation of B-cell proliferation. Acts by up-regulating the expression of viral EBNA1-6, LMP1, LMP2A and LMP2B genes, as well as several host genes inc...
TMPH-02846	BICD2 Protein, Mouse, Recombinant (GST)	Mouse	E. coli
	Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction...
TMPY-04547	PBK/TOPK Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	PDZ binding kinase (PBK), also known as TOPK (T-LAK cell-originated protein kinase), is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family, and has all the chara...
TMPH-01621	BRCC3 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes...
TMPJ-00936	CCND2 Protein, Human, Recombinant (His)	Human	E. coli
	CCND2，also known as G1/S-specific cyclin-D2，is a member of the highly conserved cyclin family. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each ...
TMPH-01526	KMT2E Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Associates with chromatin regions downstream of transcriptional start sites of active genes and thus regulates gene transcription. Chromatin interaction is mediated via the binding to tri-methylated histone H3 at 'Lys-4'...
TMPY-04443	NEK3 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus Insect Cells
	NEK3 (NIMA (never in mitosis gene a)-related expressed kinase 3), contains 1 protein kinase domain and is a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. Members of the NEK family of...
TMPY-02763	DEP-1 Protein, Human, Recombinant (aa 997-1337, His)	Human	E. coli
	DEP1 / PTPRJ (Receptor-type tyrosine-protein phosphatase eta) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, includin...
TMPY-02399	TRF1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Telomeric repeat binding factor 1 (TRF1), also known as TERF1, the shelterin complex, which modulates the telomere structures. TRF1 protein structure contains a C-terminal Myb motif, a dimerization domain near its N-term...
TMPY-03397	TPPP3 Protein, Human, Recombinant (His)	Human	E. coli
	TPPP3, a member of the Tubulin polymerization-promoting protein family, is an intrinsically unstructured protein that induces tubulin polymerization. TPPP3 is a marker in the developing musculoskeletal system. In tendons...
TMPH-03753	MYLK Protein, Human, Recombinant (His)	Human	E. coli
	Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phos...

MAD2L1 Protein, Human, Recombinant (His)

TMPY-02238

Species: Human

Expression System: E. coli

PTP1B Protein, Human, Recombinant (His)

TMPY-04125

Species: Human

Expression System: E. coli

KIF18B Protein, Human, Recombinant (His & Myc)

TMPH-01592

Species: Human

Expression System: E. coli

CEP57 Protein, Human, Recombinant (GST)

TMPY-04025

Species: Human

Expression System: E. coli

RAE1 Protein, Human, Recombinant (GST)

TMPH-01704

Species: Human

Expression System: E. coli

CHMP7 Protein, Human, Recombinant (His)

TMPH-01081

Species: Human

Expression System: E. coli

CHS1 Protein, S. cerevisiae, Recombinant (His)

TMPH-03438

Species: Saccharomyces cerevisiae

Expression System: E. coli

FcRH5/FcRL5 Protein, Human, Recombinant (His)

TMPK-00618

Species: Human

Expression System: HEK293 Cells

CDC25C Protein, Human, Recombinant (His)

TMPH-01703

Species: Human

Expression System: E. coli

FcRH5/FcRL5 Protein, Mouse, Recombinant (His)

TMPK-01039

Species: Mouse

Expression System: HEK293 Cells

FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-01145

Species: Human

Expression System: HEK293 Cells

FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

TMPK-00619

Species: Human

Expression System: HEK293 Cells

NEK7 Protein, Human, Recombinant (His & GST)

TMPY-04558

Species: Human

Expression System: Baculovirus Insect Cells

CTDP1 Protein, Mouse, Recombinant (His & Myc)

TMPH-02884

Species: Mouse

Expression System: E. coli

MOB4A/MOB1B Protein, Human, Recombinant (GST)

TMPY-03442

Species: Human

Expression System: E. coli

Vasohibin-2/VASH2 Protein, Human, Recombinant (His & SUMO)

TMPH-02304

Species: Human

Expression System: E. coli

PTP1C Protein, Human, Recombinant (His)

TMPJ-00465

Species: Human

Expression System: E. coli

MKI67 Protein, Human, Recombinant (GST)

TMPJ-01436

Species: Human

Expression System: E. coli

CDKN1B Protein, Human, Recombinant (His)

TMPJ-00972

Species: Human

Expression System: E. coli

SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST)

TMPY-03296

Species: Mouse

Expression System: Baculovirus Insect Cells

TMPO Protein, Human, Recombinant (His)

TMPJ-00960

Species: Human

Expression System: E. coli

Epstein-Barr virus (strain AG876) EBNA2 Protein (His & Myc)

TMPH-00536

Species: EBV

Expression System: P. pastoris (Yeast)

BICD2 Protein, Mouse, Recombinant (GST)

TMPH-02846

Species: Mouse

Expression System: E. coli

PBK/TOPK Protein, Human, Recombinant (His)

TMPY-04547

Species: Human

Expression System: Baculovirus Insect Cells

BRCC3 Protein, Human, Recombinant (His & SUMO)

TMPH-01621

Species: Human

Expression System: E. coli

CCND2 Protein, Human, Recombinant (His)

TMPJ-00936

Species: Human

Expression System: E. coli

KMT2E Protein, Human, Recombinant (His & Myc)

TMPH-01526

Species: Human

Expression System: E. coli

NEK3 Protein, Mouse, Recombinant (His & GST)

TMPY-04443

Species: Mouse

Expression System: Baculovirus Insect Cells

DEP-1 Protein, Human, Recombinant (aa 997-1337, His)

TMPY-02763

Species: Human

Expression System: E. coli

TRF1 Protein, Human, Recombinant (His)

TMPY-02399

Species: Human

Expression System: Baculovirus Insect Cells

TPPP3 Protein, Human, Recombinant (His)

TMPY-03397

Species: Human

Expression System: E. coli

MYLK Protein, Human, Recombinant (His)

TMPH-03753

Species: Human

Expression System: E. coli

カタログ番号	製品名
L8100	Cell Cycle Compound Library		677 compounds
	A unique collection of 677 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);

ライブラリー

Cell Cycle Compound Library

L8100

Compounds: 677