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天然化合物

リコンビナントタンパク質

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カタログ番号	製品名	別名	ターゲット
T9073	SRS16-86		Ferroptosis
	SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.		Ferroptosis
T14960	Chroman 1		ROCK
	Chroman 1 is an inhibitor of ROCK2 (IC50: 1 nM).		ROCK
T4612	NS309		EGFR , Potassium Channel , HER
	NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 µM for SK channels and 10-90 nM for IK channels). It can also activat...		EGFR , Potassium Channel , HER
T7748	Dermorphin TFA		Others , Opioid Receptor
	Dermorphin TFA is a new class of opioids-like peptides		Others , Opioid Receptor
T1030	Triprolidine hydrochloride monohydrate	Triprolidine hydrochloride	Histamine Receptor
	Triprolidine hydrochloride monohydrate is a histamine H1 antagonist used in allergic rhinitis, asthma.		Histamine Receptor
T0862	Diphenidol hydrochloride	Diphenidol HCl,Difenidol hydrochloride	Sodium Channel , AChR
	Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.		Sodium Channel , AChR
T16545	Pivanex	Pivalyloxymethyl butyrate,AN-9	Apoptosis , HDAC , Bcr-Abl
	Pivanex (Pivalyloxymethyl butyrate) is an orally active HDAC inhibitor and an antimetastatic and antiangiogenic agent. Pivanex downregulates the Bcr-Abl protein and enhances apoptosis.		Apoptosis , HDAC , Bcr-Abl
T4641	Branaplam	LMI 070,NVS-SM1	Others , Potassium Channel , DNA/RNA Synthesis
	Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.		Others , Potassium Channel , DNA/RNA Synthesis
T15781	LP-935509		Serine/threonin kinase , AAK1 (AP2 associated kinase 1)
	LP-935509 is highly brain-penetrant and reverses fully established pain behavior following the SNL procedure. LP-935509 is also an effective inhibitor of BIKE (IC50=14 nM) and a modest inhibitor of GAK (IC50=320 nM). LP-...		Serine/threonin kinase , AAK1 (AP2 associated kinase 1)
T0370	Pheniramine maleate	Daneral,Inhiston,Trimetose	5-HT Receptor , Histamine Receptor
	Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re...		5-HT Receptor , Histamine Receptor
T7404	Dermorphin		Opioid Receptor
	Dermorphin is agonist of μ-opioid receptor (MOR) agonist.		Opioid Receptor
T36851L	Peptide5 acetate		Others
	Peptide5 acetate reduces animal swelling, astrogliosis, and neuronal cell death after spinal cord injury. Peptide5 acetate significantly reduces the degree of spinal cord injury (SCI) in a rodent ex vivo model.		Others
T12718L	RG7800	RO6885247	Others , DNA/RNA Synthesis
	RG7800 (RO6885247) has the potential for spinal muscular atrophy treatment. RG7800 is an SMN2 splicing modifier.		Others , DNA/RNA Synthesis
T13142L	Theodrenaline hydrochloride	Theodrenaline hydrochloride(13460-98-5 Free base)	SARS-CoV
	Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia.		SARS-CoV
T24754	Hh-Ag1.5	SAG-1.5,SAG1.5,SAG 1.5	Hedgehog/Smoothened
	Hh-Ag1.5 (SAG-1.5) is a potent Hedgehog (Hh) agonist (EC50: 1 nM) and Smoothened (Smo) receptor agonist, with an EC50 of 1 nM and Ki values between 0.5 and 2.3 nM for Smo. Hh-Ag1.5-mediated reprogramming breaks the quies...		Hedgehog/Smoothened
T78575	KCL-286		Retinoid Receptor
	KCL-286 is an orally available and potent retinoic acid receptor beta agonist for the amelioration of spinal cord injury (SCI).		Retinoid Receptor
T3336	Rg3039	PF-06687859	Others
	Rg3039 (PF-06687859) is a potent DcpS inhibitor. DcpS is a therapeutic target for spinal muscular atrophy. Spinal muscular atrophy (SMA) is caused by deletion or mutation of both copies of the SMN1 gene which produces an...		Others
T1065	Baclofen	Lioresal	GABA Receptor
	Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist sp...		GABA Receptor
T12935	SMN-C3	MV8T2MCK57	DNA/RNA Synthesis
	SMN-C3 (MV8T2MCK57) is an orally active modulator of SMN2 splicing, and has the potential to treat spinal muscular atrophy (SMA).		DNA/RNA Synthesis
T8630	Baclofen hydrochloride	4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride	GABA Receptor
	Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, espe...		GABA Receptor
T21983L	PKI 14-22 amide, myristoylated Acetate	PKI 14-22 amide, myristoylated Acetate(201422-03-9 Free base)	PKA
	PKI 14-22 amide, myristoylated Acetate inhibit cAMP-dependent protein kinase (PKA) and blocks hyperalgesia produced by spinal administration of 8-bromo-cAMP.		PKA
T77445	Apitegromab	SRK-015	Opioid Receptor
	Apitegromab (SRK-015) is a new myostatin inhibitor, an antibody targeting myostatin precursor, which can be used to study neuromuscular diseases including spinal muscular atrophy.		Opioid Receptor
T34399	Rovatirelin	KPS-0373,S0373,S-0373,S 0373	AChE
	Rovatirelin (S-0373) is a newly synthesized thyrotropin-releasing hormone (TRH) analog that ameliorates cytosine arabinoside-induced motor dysfunction in a rat model of spinal cerebellar degeneration via acetylcholine an...		AChE
T60086	TTBK1-IN-2	N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Microtubule Associated
	TTBK1-IN-2 (N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine) is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 µM. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures ...		Microtubule Associated
T27397	Gacyclidine	GK 11,OTO311,OTO-311,OTO 311,GK-11	NMDAR
	Gacyclidine (OTO311) is a small molecule N-methyl-D-aspartate (NMDA) receptor antagonist. Local injection of Gacyclidine in the cochlea inhibits salicylate-induced tinnitus and can be used to treat brain injury, spinal c...		NMDAR
T23215L	(R)-3,4-DCPG HCl	(R)-3,4-DCPG HCl(201730-10-1 Free base)	GluR
	(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord.		GluR
T0029	Procaine	Duracaine,Spinocaine,Novocaine,Vitamin H3	Histone Demethylase , DNA/RNA Synthesis , Sodium Channel
	Procaine (Vitamin H3) is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block.		Histone Demethylase , DNA/RNA Synthesis , Sodium Channel
TP1442	Neuromedin B		Endogenous Metabolite
	Neuromedin B (NMB) is one of the bombesin (BN)-related peptides in mammals. It was originally purified from pig spinal cords, and it has been shown to be present in central nervous system as well as in gastrointestinal t...		Endogenous Metabolite
T1198	Tetracaine hydrochloride	Amethocaine hydrochloride,Amethocalne HCl,Tetracaine HCl	Calcium Channel , Sodium Channel
	Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been use...		Calcium Channel , Sodium Channel
T73475	SMN-C2		DNA/RNA Synthesis
	SMN-C2 is a selective regulator of SMN2 gene splicing, a risdiplam analogue, a selective RNA-binding ligand that regulates pre-mRNA splicing and acts by binding to SMN2 pre-mRNA.SMN-C2 has the potential to be used in the...		DNA/RNA Synthesis
T28978	Tirilazad mesylate	U-74006 mesylate,U74006 mesylate,U 74006 mesylate,U 74006F mesylate,U-74006F mesylate,U74006F mesylate	Antiviral
	Tirilazad mesylate (U 74006F) is a non-glucocorticoid, lipid peroxidation inhibitor with antiviral activity and neuroprotective activity.Tirilazad mesylate confines intracellular intramembranous foci, attenuates spinal c...		Antiviral
T67929	Linoleoyl glycine
	Linoleoyl glycine, a modified polyunsaturated fatty acid, is an endogenous homologue of linoleoyl glycine. Linoleoyl glycine activates human KCNQ1/KCNE1 (hKCNQ1/hKCNE1) channels expressed in xenopus oocytes from mammalia...
T10893	CS-722 Free base		Others
	CS-722 Free base is a synthetic central muscle relaxant with muscle relaxant activity and inhibitory effect on spinal reflex. CS-722 Free base may inhibit spontaneous inhibitory post-synaptic current and excitatory post-...		Others
T7218	Endomorphin 2		Opioid Receptor
	Endomorphins-2 (EM-2) could decrease both the frequency and amplitude of the sEPSC of the motoneurons in lamina IX, which was reversed by the MOR antagonist CTOP. EM-2-IR fibers originated from primary afferent fibers f...		Opioid Receptor
T14198	ALX-1393		GlyT
	ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits the activity of spontaneous networks by inducing glycinergic tetanic cu...		GlyT
T3354	BIA 10-2474	BIA10-2474	FAAH , Autophagy
	BIA 10-2474 is a long-acting reversible inhibitor of fatty acid amide hydrolase (FAAH) that increases levels of the neurotransmitter anandamide in the central nervous system and in peripheral tissues (that is, the rest o...		FAAH , Autophagy
T76863	Elezanumab	AE12-1Y-QL,ABT-555	TGF-beta/Smad
	Elezanumab(ABT-555) is a potent human anti-RGMa monoclonal antibody.Elezanumab exerts its inhibitory effect on RGMa-mediated BMP signaling through the SMAD1/5/8 pathway, with an IC50 of approximately 97 pM.Elezanumab pro...		TGF-beta/Smad
T28778	Silperisone HCl	RGH5002,SILA336,RGH-5002,Silperisone hydrochloride,SILA-336
	Silperisone HCl (RGH-5002) blocks sodium and calcium channels in cells, decreases excitability and contractility of muscle cells, reduces peripheral tone, and acts as a muscle relaxant and peripheral vasodilator. Silperi...
T35689	MTP 131 acetate		Others
	MTP 131 is a mitochondria-targeted peptide antioxidant.1,2It localizes to the mitochondria and reducestert-butyl hydroperoxide-induced lipid peroxidation and apoptosis in SH-SY5Y cells when used at concentrations ranging...		Others
T31168	D153249	D 153249,D-153249
	D153249 is a promoter of spinal muscular atrophy (SMA).
T33324	Methionyl-tyrosyl-lysine	Met-tyr-lys
	Methionyl-tyrosyl-lysine is a tripeptide from the spinal cord.
T27243	Efipladib	PLA-902,PLA 902,PLA902
	Efipladib is a phospholipase inhibitor. Efipladib decreases nociceptive responses without affecting PGE2 levels in the cerebral spinal fluid.
T32658	Leteprinim potassium	SPI-205,AIT-082,SPI 205,AIT082,AIT 082,SPI205
	Leplinine (AIT-082, SPI-205) is a neurotrophic agent that may be used to treat Alzheimer's disease and spinal cord injury.
T3290L	Pikamilone Sodium	GABA-NG,Nicotinoyl-GABA sodium salt,GABA NG,GABANG,Pikamilone Na
	Pikamilone Sodium is a prodrug of GABA used for therapy of neurogenic bladder in spinal and benign prostatic hyperplasia.
T25009	AK 275	AK275,AK-275
	AK 275 is a calpain inhibitor that prevents degradation of cytoskeletal and myelin proteins in spinal cord in vitro.
T17306	(R)-Baclofen hydrochloride	Arbaclofen hydrochloride	GABA Receptor
	Arbaclofen hydrochloride, a Gamma-Aminobutyric Acid derivative, is a specific agonist of GABA-B receptors, it is used to treat spasticity, especially that due to spinal cord damage. It acts at spinal and supraspinal site...		GABA Receptor
T71356	Lanperisone HCl
	Lanperisone, also known as NK433, is a muscle relaxant. NK433 inhibited the facilitation of the flexor reflex mediated by group II afferent fibers that was induced by intrathecal administration of noradrenaline-HCl. NK43...
T70078	Fadolmidine
	Fadolmidine is a novel and potent alpha2 -adrenoceptor (alpha2) -AR) agonist developed for spinal analgesia.
T14187	ALLM	Calpain inhibitor II	Others
	ALLM (Calpain inhibitor II), a potent calpain and cathepsin protease inhibitor, not only prevents neuronal cell death but also enhances chronic neurological function following spinal cord injury (SCI)[1][2].		Others
T21338	Methylprednisolone Acetate	Depo-Medrate,Depometicort,Depo-Medrin,Depo-medrol,Depomedrone,Lemod	Reactive Oxygen Species
	Methylprednisolone Acetate(Depo-Medrate) has the ability to inhibit oxygen free radicals and can be used to treat acute spinal cord injuries.		Reactive Oxygen Species

Compounds

Target: EGFR, Potassium Channel, HER

Dermorphin TFA

T7748

Synonym:

Target: Others, Opioid Receptor

Triprolidine hydrochloride monohydrate

T1030

Synonym: Triprolidine hydrochloride

Target: Histamine Receptor

Diphenidol hydrochloride

T0862

Synonym: Diphenidol HCl,Difenidol hydrochloride

Target: Sodium Channel, AChR

Pivanex

T16545

Synonym: Pivalyloxymethyl butyrate,AN-9

Target: Apoptosis, HDAC, Bcr-Abl

Branaplam

T4641

Synonym: LMI 070,NVS-SM1

Target: Others, Potassium Channel, DNA/RNA Synthesis

LP-935509

T15781

Synonym:

Target: Serine/threonin kinase, AAK1 (AP2 associated kinase 1)

Pheniramine maleate

T0370

Synonym: Daneral,Inhiston,Trimetose

Target: 5-HT Receptor, Histamine Receptor

Dermorphin

T7404

Synonym:

Target: Opioid Receptor

Target: Others, DNA/RNA Synthesis

Theodrenaline hydrochloride

T13142L

Synonym: Theodrenaline hydrochloride(13460-98-5 Free base)

Target: SARS-CoV

Hh-Ag1.5

T24754

Synonym: SAG-1.5,SAG1.5,SAG 1.5

Target: Hedgehog/Smoothened

KCL-286

T78575

Synonym:

Target: Retinoid Receptor

Target: GABA Receptor

SMN-C3

T12935

Synonym: MV8T2MCK57

Target: DNA/RNA Synthesis

Baclofen hydrochloride

T8630

Synonym: 4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride

Target: GABA Receptor

PKI 14-22 amide, myristoylated Acetate

T21983L

Synonym: PKI 14-22 amide, myristoylated Acetate(201422-03-9 Free base)

Target: Opioid Receptor

Rovatirelin

T34399

Synonym: KPS-0373,S0373,S-0373,S 0373

Target: AChE

TTBK1-IN-2

T60086

Synonym: N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Target: Microtubule Associated

Gacyclidine

T27397

Synonym: GK 11,OTO311,OTO-311,OTO 311,GK-11

Target: NMDAR

(R)-3,4-DCPG HCl

T23215L

Synonym: (R)-3,4-DCPG HCl(201730-10-1 Free base)

Target: GluR

Procaine

T0029

Synonym: Duracaine,Spinocaine,Novocaine,Vitamin H3

Target: Histone Demethylase, DNA/RNA Synthesis, Sodium Channel

Neuromedin B

TP1442

Synonym:

Target: Endogenous Metabolite

Tetracaine hydrochloride

T1198

Synonym: Amethocaine hydrochloride,Amethocalne HCl,Tetracaine HCl

Target: Calcium Channel, Sodium Channel

SMN-C2

T73475

Synonym:

Target: DNA/RNA Synthesis

Tirilazad mesylate

T28978

Synonym: U-74006 mesylate,U74006 mesylate,U 74006 mesylate,U 74006F mesylate,U-74006F mesylate,U74006F mesylate

Target: Opioid Receptor

Target: FAAH, Autophagy

Elezanumab

T76863

Synonym: AE12-1Y-QL,ABT-555

Target: TGF-beta/Smad

Silperisone HCl

T28778

Synonym: RGH5002,SILA336,RGH-5002,Silperisone hydrochloride,SILA-336

Synonym: D 153249,D-153249

Target:

Methionyl-tyrosyl-lysine

Synonym: PLA-902,PLA 902,PLA902

Target:

Leteprinim potassium

T32658

Synonym: SPI-205,AIT-082,SPI 205,AIT082,AIT 082,SPI205

Target:

Pikamilone Sodium

T3290L

Synonym: GABA-NG,Nicotinoyl-GABA sodium salt,GABA NG,GABANG,Pikamilone Na

Target:

AK 275

T25009

Synonym: AK275,AK-275

Target:

(R)-Baclofen hydrochloride

T17306

Synonym: Arbaclofen hydrochloride

Target: GABA Receptor

Synonym: Calpain inhibitor II

Target: Others

Methylprednisolone Acetate

T21338

Synonym: Depo-Medrate,Depometicort,Depo-Medrin,Depo-medrol,Depomedrone,Lemod

Target: Reactive Oxygen Species

カタログ番号	製品名	別名	ターゲット
T3S0870	Paederosidic acid methyl ester		ATPase , Potassium Channel , NO Synthase
	Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.		ATPase , Potassium Channel , NO Synthase
T3896	Shanzhiside methyl ester		Glucagon Receptor
	Shanzhiside methylester reduces neuropathic pain by activating spinal GLP-1 receptors and subsequently stimulating microglial β-endorphin expression via the p38 MAPK signaling.		Glucagon Receptor
T6S1010	Allomatrine		Others
	Allomatrine is a natural product from Sophora alopecuroides L. Allomatrine, when given i.c.v., may stimulate the descending dynorphinergic neuron, resulting in the stimulation of KORs in the spinal cord.		Others
T5S1708	Dendrobine		Others , Influenza Virus
	1. Dendrobine has a slight but demonstrable analgesic and antipyretic action. 2. Dendrobine produces moderate hyperglycemia, diminishes cardiac activity in large doses, lowers the blood pressure. 3. Dendrobine on the ele...		Others , Influenza Virus
T0012	Cinchonine	LA40221,(8R,9S)-Cinchonine	Apoptosis , P-gp , Parasite
	Cinchonine (LA40221), a local anesthetic of the amide type, now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local narcotics and its parenteral use is restricted to spi...		Apoptosis , P-gp , Parasite
T2768	Saikosaponin A		NF-κB , Antibacterial , Liver X Receptor
	Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-bacterial activities. It can effectively attenuate neuropath...		NF-κB , Antibacterial , Liver X Receptor
T5S0661	Koumine		Others
	1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a significant analgesic effect in rodent behavioral models of infla...		Others
T4S0969	Obtusifolin		Antioxidant , NF-κB
	1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be...		Antioxidant , NF-κB
TN1717	Guvacine		GABA Receptor
	Guvacine can enhance the inhibition of spinal neurones by GABA.		GABA Receptor
T37219	N-Palmitoyl Glycine
	The acyl amides are a family of endogenous lipids that act as potent modulators of pain and inflammation. The best characterized members of this family are the arachidonoyl amides, which includes N-arachidonoyl ethanolam...

天然物製品

Paederosidic acid methyl ester

T3S0870

Synonym:

Target: ATPase, Potassium Channel, NO Synthase

Shanzhiside methyl ester

T3896

Synonym:

Target: Glucagon Receptor

Target: Others, Influenza Virus

Cinchonine

T0012

Synonym: LA40221,(8R,9S)-Cinchonine

Target: Apoptosis, P-gp, Parasite

Saikosaponin A

T2768

Synonym:

Target: NF-κB, Antibacterial, Liver X Receptor

Target: Antioxidant, NF-κB

Guvacine

TN1717

Synonym:

Target: GABA Receptor

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPK-00735	CXCL13/BCA-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve li...
TMPJ-00261	TGF beta 2 Protein, Mouse/Rat, Recombinant	Mouse,Rat	Human Cells
	Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofaci...
TMPY-00432	TREM-2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-01148	TREM-2 Protein, Human, Recombinant (His)	Human	HEK293
	Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-01703	TREM-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPK-00734	CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve li...
TMPK-00018	CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo)	Human	E. coli
	Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve li...
TMPK-00017	CXCL13/BCA-1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve li...
TMPY-02840	Ubiquitin Activating Enzyme E1/UBA1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	UBE1, also known as UBA1, belongs to the ubiquitin-activating E1 family. UBE1 gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cl...
TMPJ-01408	HDGFRP3 Protein, Human, Recombinant (His)	Human	Human Cells
	Hepatoma-Derived Growth Factor-Related Protein 3 (HDGFRP3) belongs to the HDGF family. HDGFRP3 can be found in testis, heart, spinal cord and brain. HDGFRP3 localizes to the nucleus and contains one PWWP domain. HDGFRP3 ...
TMPY-00320	APOA1BP Protein, Human, Recombinant (His)	Human	HEK293
	APOA1BP, now renamed NAXE, encodes an epimerase essential in the cellular metabolite repair for NADHX and NADPHX. The enzyme catalyzes the epimerization of NAD(P)HX, thereby avoiding the accumulation of toxic metabolites...
TMPK-01161	LAMP5 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesi...
TMPY-03451	SPF30 Protein, Human, Recombinant (His)	Human	E. coli
	SMNDC1 gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been iden...
TMPH-02678	GPI Protein, Mouse, Recombinant (His)	Mouse	Yeast
	In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also ac...
TMPK-00360	DLL4 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Delta-like protein 4 (DLL4) is a type I membrane protein belonging to the Delta/Serrate/Lag2 (DSL) family of Notch ligands. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell pro...
TMPH-02677	GPI Protein, Mouse, Recombinant (B2M & His)	Mouse	E. coli
	In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also ac...
TMPH-01391	GPI Protein, Human, Recombinant (His)	Human	E. coli
	In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also ac...
TMPK-01234	LAMP5 Protein, Human, Recombinant (His)	Human	HEK293
	Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesi...
TMPH-02262	TUBB3 Protein, Human, Recombinant (GST)	Human	E. coli
	Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon...
TMPY-04751	VRK1 Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	VRK1 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. Serine/threonine protein kinases are tumor suppressor that controls the activity of AMP-activated protein kinase family me...
TMPY-04560	VRK1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	VRK1 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. Serine/threonine protein kinases are tumor suppressor that controls the activity of AMP-activated protein kinase family me...
TMPJ-00701	Carbonic Anhydrase 11 Protein, Human, Recombinant (His)	Human	Human Cells
	Carbonic Anhydrase-Related Protein 11 (CA11) is a secreted protein member of the α-carbonic anhydrase family. Carbonic Anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of ...
TMPY-01620	MDGA2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	MAM domain-containing glycosylphosphatidylinositol anchor protein 2, also known as MAM domain-containing protein 1, MDGA2, and MAMDC1, is a cell membrane protein that contains six Ig-like (immunoglobulin-like) domains an...
TMPJ-00584	Bc1-w Protein, Human, Recombinant (His)	Human	E. coli
	Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing thre...
TMPJ-01398	ITM2B Protein, Human, Recombinant (His)	Human	Human Cells
	Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other ti...
TMPJ-01185	SULT1C4 Protein, Human, Recombinant (His)	Human	E. coli
	Human Sulfotransferase (SULT1C4) is an enzyme that in humans is encoded by the SULT1C4 gene, belongs to the sulfotransferase 1 family. SULT1C4 is expressed at high levels in fetal lung and kidney and at low levels in fet...
TMPJ-00763	ANG Protein, Human, Recombinant	Human	E. coli
	Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular t...
TMPY-03969	SUSD4 Protein, Human, Recombinant (mFc)	Human	HEK293
	SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and ...
TMPJ-00767	PDGF-AA Protein, Human, Recombinant	Human	E. coli
	Platelet-derived growth factor subunit A (PDGFA), belongs to the PDGF/VEGF growth factor family. PDGFA is a secreted protein, stored in platelet alpha-granules and released by platelets upon wounding. PDGFA is potent mit...
TMPH-01019	BMP-7 Protein, Human, Recombinant (GST)	Human	E. coli
	Growth factor of the TGF-beta superfamily that plays important role in various biological processes, including embryogenesis, hematopoiesis, neurogenesis and skeletal morphogenesis. Initiates the canonical BMP signaling ...
TMPY-03963	CALCB Protein, Human, Recombinant (mFc)	Human	HEK293
	CALCB, also known as CGPR and calcitonin 2, belongs to the calcitonin family. CALCB is a calcitonin (CT) peptide which may play a role in the mediation of human inflammatory diseases. It is highly expressed in the skin, ...
TMPY-02804	FGF-14 Protein, Human, Recombinant (isoform 1B)	Human	E. coli
	FGF14 is a member of the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic deve...
TMPY-02196	VAPB Protein, Human, Recombinant (His)	Human	E. coli
	Vesicle-associated membrane protein-associated protein B / C, also known as VAMP-B/VAMP-C, VAMP-associated protein B/C, VAP-B/VAP-C and VAPB, is a single-pass type IV membrane protein that belongs to the VAMP-associated ...
TMPJ-00768	PDGF-AA Protein, Human, Recombinant (His)	Human	E. coli
	Platelet-derived growth factor subunit A (PDGFA), belongs to the PDGF/VEGF growth factor family. PDGFA is a secreted protein, stored in platelet alpha-granules and released by platelets upon wounding. PDGFA is potent mit...
TMPY-04033	FGF-14 Protein, Canine, Recombinant	Canine	E. coli
	FGF14 is a member of the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic deve...
TMPJ-00490	Serpin A5 Protein, Human, Recombinant (His)	Human	Human Cells
	Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent i...
TMPH-00879	ASCL1 Protein, Human, Recombinant (His)	Human	E. coli
	Transcription factor that plays a key role in neuronal differentiation: acts as a pioneer transcription factor, accessing closed chromatin to allow other factors to bind and activate neural pathways. Directly binds the E...
TMPY-02759	Kallikrein 6/KLK6 Protein, Human, Recombinant (His)	Human	HEK293
	KLK6 (kallikrein-related peptidase 6), also known as Klk7, belongs to the peptidase S1 family, Kallikrein subfamily. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence...
TMPY-02717	GPR37 Protein, Human, Recombinant (His)	Human	HEK293
	GPR37 (cathepsin Z) is an orphan receptor that belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors are a large protein family comprised of transmembrane receptors that sense molecules outside ...
TMPY-03521	DcR3 Protein, Human, Recombinant (hFc)	Human	Baculovirus-Insect Cells
	Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) also known as DcR3(Decoy Receptor 3) and M68 is the tumor necrosis factor receptor superfamily. DcR3/TNFRSF6B belongs to the tumor necrosis factor receptor ...
TMPY-04539	ERK2 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, diffe...
TMPY-01221	Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc)	Mouse	HEK293
	Reticulon 4 receptor (RTN4R), also known as Nogo-66 Receptor (NgR), is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. Mouse RTN4R cDNA contains 1 LRP (Le...
TMPY-01056	Nogo Receptor/RTN4R Protein, Human, Recombinant (His & hFc)	Human	HEK293
	Reticulon 4 receptor (RTN4R), also known as Nogo-66 Receptor (NgR), is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. Mouse RTN4R cDNA contains 1 LRP (Le...
TMPY-04571	ERK2 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, diffe...
TMPY-01797	Frizzled 10 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Frizzled-1, also known as Fz-1, CD35 and FZD1, is a multi-pass membrane protein which belongs to theG-protein coupled receptor Fz/Smo family. Frizzled-1 / FZD1 is abundantly expressed in the cerebellum, followed by ce...
TMPY-01876	HSP60 Protein, Human, Recombinant (His & GST)	Human	E. coli
	HSPD1, also known as HSP60, is a member of the chaperonin family. HSPD1 may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins ...
TMPY-01798	Frizzled 10 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Frizzled-1, also known as Fz-1, CD35 and FZD1, is a multi-pass membrane protein which belongs to theG-protein coupled receptor Fz/Smo family. Frizzled-1 / FZD1 is abundantly expressed in the cerebellum, followed by ce...
TMPY-01891	ECE2 Protein, Human, Recombinant (His)	Human	HEK293
	Endothelin-converting enzyme 2, also known as ECE-2, is a metalloprotease that possesses many properties consistent with it being a neuropeptide-processing enzyme. Endothelin-converting enzymes (ECEs) are the key enzy...
TMPY-01992	Kallikrein 8/KLK8 Protein, Human, Recombinant (His)	Human	HEK293
	Kallikrein-8, also known as Neuropsin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein, and KLK8 is a secreted protein that belongs to the peptidase S1 family and Ka...
TMPY-04140	Frizzled 10 Protein, Human, Recombinant (hFc)	Human	HEK293
	Frizzled-1, also known as Fz-1, CD35 and FZD1, is a multi-pass membrane protein which belongs to theG-protein coupled receptor Fz/Smo family. Frizzled-1 / FZD1 is abundantly expressed in the cerebellum, followed by ce...
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CXCL13/BCA-1 Protein, Mouse, Recombinant (His)

TMPK-00735

Species: Mouse

Expression System: HEK293

TGF beta 2 Protein, Mouse/Rat, Recombinant

TMPJ-00261

Species: Mouse,Rat

Expression System: Human Cells

TREM-2 Protein, Mouse, Recombinant (hFc)

TMPY-00432

Species: Mouse

Expression System: HEK293

TREM-2 Protein, Human, Recombinant (His)

TMPY-01148

Species: Human

Expression System: HEK293

TREM-2 Protein, Mouse, Recombinant (His)

TMPY-01703

Species: Mouse

Expression System: HEK293

CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc)

TMPK-00734

Species: Mouse

Expression System: HEK293

CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo)

TMPK-00018

Species: Human

Expression System: E. coli

CXCL13/BCA-1 Protein, Human, Recombinant (hFc)

TMPK-00017

Species: Human

Expression System: HEK293

Ubiquitin Activating Enzyme E1/UBA1 Protein, Human, Recombinant (His & GST)

TMPY-02840

Species: Human

Expression System: Baculovirus-Insect Cells

HDGFRP3 Protein, Human, Recombinant (His)

TMPJ-01408

Species: Human

Expression System: Human Cells

APOA1BP Protein, Human, Recombinant (His)

TMPY-00320

Species: Human

Expression System: HEK293

LAMP5 Protein, Mouse, Recombinant (hFc)

TMPK-01161

Species: Mouse

Expression System: HEK293

SPF30 Protein, Human, Recombinant (His)

TMPY-03451

Species: Human

Expression System: E. coli

GPI Protein, Mouse, Recombinant (His)

TMPH-02678

Species: Mouse

Expression System: Yeast

DLL4 Protein, Human, Recombinant (His & Avi)

TMPK-00360

Species: Human

Expression System: HEK293

GPI Protein, Mouse, Recombinant (B2M & His)

TMPH-02677

Species: Mouse

Expression System: E. coli

GPI Protein, Human, Recombinant (His)

TMPH-01391

Species: Human

Expression System: E. coli

LAMP5 Protein, Human, Recombinant (His)

TMPK-01234

Species: Human

Expression System: HEK293

TUBB3 Protein, Human, Recombinant (GST)

TMPH-02262

Species: Human

Expression System: E. coli

VRK1 Protein, Human, Recombinant

TMPY-04751

Species: Human

Expression System: Baculovirus-Insect Cells

VRK1 Protein, Human, Recombinant (His & GST)

TMPY-04560

Species: Human

Expression System: Baculovirus-Insect Cells

Carbonic Anhydrase 11 Protein, Human, Recombinant (His)

TMPJ-00701

Species: Human

Expression System: Human Cells

MDGA2 Protein, Mouse, Recombinant (His)

TMPY-01620

Species: Mouse

Expression System: HEK293

Bc1-w Protein, Human, Recombinant (His)

TMPJ-00584

Species: Human

Expression System: E. coli

ITM2B Protein, Human, Recombinant (His)

TMPJ-01398

Species: Human

Expression System: Human Cells

SULT1C4 Protein, Human, Recombinant (His)

TMPJ-01185

Species: Human

Expression System: E. coli

ANG Protein, Human, Recombinant

TMPJ-00763

Species: Human

Expression System: E. coli

SUSD4 Protein, Human, Recombinant (mFc)

TMPY-03969

Species: Human

Expression System: HEK293

PDGF-AA Protein, Human, Recombinant

TMPJ-00767

Species: Human

Expression System: E. coli

BMP-7 Protein, Human, Recombinant (GST)

TMPH-01019

Species: Human

Expression System: E. coli

CALCB Protein, Human, Recombinant (mFc)

TMPY-03963

Species: Human

Expression System: HEK293

FGF-14 Protein, Human, Recombinant (isoform 1B)

TMPY-02804

Species: Human

Expression System: E. coli

VAPB Protein, Human, Recombinant (His)

TMPY-02196

Species: Human

Expression System: E. coli

PDGF-AA Protein, Human, Recombinant (His)

TMPJ-00768

Species: Human

Expression System: E. coli

FGF-14 Protein, Canine, Recombinant

TMPY-04033

Species: Canine

Expression System: E. coli

Serpin A5 Protein, Human, Recombinant (His)

TMPJ-00490

Species: Human

Expression System: Human Cells

ASCL1 Protein, Human, Recombinant (His)

TMPH-00879

Species: Human

Expression System: E. coli

Kallikrein 6/KLK6 Protein, Human, Recombinant (His)

TMPY-02759

Species: Human

Expression System: HEK293

GPR37 Protein, Human, Recombinant (His)

TMPY-02717

Species: Human

Expression System: HEK293

DcR3 Protein, Human, Recombinant (hFc)

TMPY-03521

Species: Human

Expression System: Baculovirus-Insect Cells

ERK2 Protein, Human, Recombinant (GST)

TMPY-04539

Species: Human

Expression System: Baculovirus-Insect Cells

Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc)

TMPY-01221

Species: Mouse

Expression System: HEK293

Nogo Receptor/RTN4R Protein, Human, Recombinant (His & hFc)

TMPY-01056

Species: Human

Expression System: HEK293

ERK2 Protein, Mouse, Recombinant (His & GST)

TMPY-04571

Species: Mouse

Expression System: Baculovirus-Insect Cells

Frizzled 10 Protein, Mouse, Recombinant (hFc)

TMPY-01797

Species: Mouse

Expression System: HEK293

HSP60 Protein, Human, Recombinant (His & GST)

TMPY-01876

Species: Human

Expression System: E. coli

Frizzled 10 Protein, Mouse, Recombinant (His)

TMPY-01798

Species: Mouse

Expression System: HEK293

ECE2 Protein, Human, Recombinant (His)

TMPY-01891

Species: Human

Expression System: HEK293

Kallikrein 8/KLK8 Protein, Human, Recombinant (His)

TMPY-01992

Species: Human

Expression System: HEK293

Frizzled 10 Protein, Human, Recombinant (hFc)

TMPY-04140

Species: Human

Expression System: HEK293

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カタログ番号	製品名
L2620	Anti-Neurodegenerative Disease Compound Library	2154 compounds
	A unique collection of 2154 compounds related to neurodegenerative diseases can be used for HTS or HCS；
L2630	Neuronal Differentiation Compound Library	672 compounds

ライブラリー

Anti-Neurodegenerative Disease Compound Library

L2620

Compounds: 2154

Neuronal Differentiation Compound Library

L2630

Compounds: 672