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117

天然化合物

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TargetMolキット

カタログ番号	製品名	別名	ターゲット
T8619	8-CHLOROQUINAZOLIN-4(1H)-ONE		Others
	8-CHLOROQUINAZOLIN-4(1H)-ONE is inhibitor of Poly [ADP-ribose] polymerase 1 (human)		Others
T3679	1-(4-FLUORO-PHENYL)-BUTAN-1-ONE		Others
	1-(4-FLUORO-PHENYL)-BUTAN-1-ONE is a useful organic compound for research related to life sciences. The catalog number is T3679 and the CAS number is 582-83-2.		Others
T8601	1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one	4H-Indol-4-one, 2-ethyl-1,5,6,7-tetrahydro-1-(phenylmethyl)-	Epigenetic Reader Domain
	1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one is an inhibitor Bromodomain-containing protein 4 (human).		Epigenetic Reader Domain
T50014	2-methyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one		Epigenetic Reader Domain
	2-methyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one is ligand of CBP.		Epigenetic Reader Domain
T4204	6-ethyl-7-hydroxy-4-methylchromen-2-one	6-ethyl-7-hydroxy-4-methylcoumarin	Others
	6-Ethyl-7-hydroxy-4-methylchromen-2-one is a fluorescent dye.		Others
T8563	2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one		Serine Protease
	2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.		Serine Protease
T60094	SU 4981	3-(4-Morpholinobenzylidene)indolin-2-one	VEGFR , Tyrosine Kinases
	SU 4981 is an inhibitor of VEGFR and a modulator of tyrosine kinase activity.		VEGFR , Tyrosine Kinases
T50012	4-(3-Chlorophenyl)-2(3H)-thiazolone	4-(3-chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one	Others
	4-(3-chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one has been used as a starting material for the synthesis of a variety of biologically active compounds, including antifungal, antiviral and anti-inflammatory agents.		Others
T50022	BRD4 Inhibitor 30		Others
	4-(2-fluorophenyl)-2,3-dihydro-1,3-thiazol-2-one is a thiazol-2-one analog that has been found to possess anti-inflammatory, antibacterial, antifungal, and antitumor activities.		Others
T9834	(3Z)-1-methyl-3-[2-(4-methylphenyl)-2-oxo-ethylidene]piperazin-2-one		Others
	(3Z)-1-methyl-3-[2-(4-methylphenyl)-2-oxo-ethylidene]piperazin-2-one is a chemical agent.		Others
T5095	Oxazolone	4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one	Others
	Oxazolone has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression studies of the two forms of inflammatory...		Others
T65427	5-LOX inhibitor	1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one	Lipoxygenase
	5-LOX inhibitor (1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one) is one of the impurities of itraconazole, a selective LOX-5 inhibitor.		Lipoxygenase
T10761	Ceranib-2	3-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]-4-phenyl-1H-quinolin-2-one	Apoptosis , S1P Receptor
			Apoptosis , S1P Receptor
T3586	Compound 401	2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one	DNA-PK
	Compound 401 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one) is a synthetic DNA-PK inhibitor (IC50 = 0.28 μM) that also targets mTOR but not PI3K.		DNA-PK
T8598	CHEMBL241987	2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE	Adenosine Receptor
	CHEMBL241987 targets the Adenosine receptor A3 (human)		Adenosine Receptor
T10019	1-Methylcytosine	1-methylcytosin,4-amino-1-methylpyrimidin-2(1H)-one,N-Methylcytosine	Nucleoside Antimetabolite/Analog
	1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with isoguanine.		Nucleoside Antimetabolite/Analog
T14775	Bragsin2	6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one,Bragsin 2	Others
	Bragsin2 (6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one) is a hydration-resistant cell penetrant, selective and non-competitive inhibitor of Afr guanine nucleotide exchange factor BRAG2 that inhibits Arf GTPase acti...		Others
T67856	GSK-3β inhibitor 14	1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)-	GSK-3
	GSK-3β inhibitor 14 (1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)-) is a weak GSK-3β inhibitor, IC50﹥ 100μM.		GSK-3
T8904	Riamilovir	Triazavirin,7-methylsulfanyl-3-nitro-6H-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-one	Antiviral
	Riamilovir (7-methylsulfanyl-3-nitro-6H-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-one) is a broad-spectrum antiviral drug candidate.		Antiviral
T80671	ACHE-IN-38	5,6-Dimethoxy-2-(piperidin-4-yl)methylene-indan-1-one	Antifungal
	ACHE-IN-38 is a potent Acetylcholinesterase inhibitor that can be used for the synthesis of compounds with anti-inflammatory, anti-tumor, and antibacterial activities.		Antifungal
T9007	Germinone A	3-Methyl-5-((3-nitro-[1,1'-biphenyl]-4-yl)oxy)furan-2(5H)-one	Others
	Germinone A (3-Methyl-5-((3-nitro-[1,1'-biphenyl]-4-yl)oxy)furan-2(5H)-one) is a novel potent agonist of HTL/KAI2, stimulating activity for Arabidopsis seed germination, has antitumor activity in multiple types of carcin...		Others
T23450	TCS PrP Inhibitor 13	5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One	Others
	TCS PrP Inhibitor 13 (5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One) is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.		Others
T50102	3-(2,6-dichlorophenyl)-1-methyl-7-(methylsulfanyl)-1H,2H,3H,4H-pyrimido[4,5-d][1,3]diazin-4-one		Others
	3-(2,6-dichlorophenyl)-1-methyl-7-(methylsulfanyl)-1H,2H,3H,4H-pyrimido[4,5-d][1,3]diazin-4-one is a compound that has been extensively investigated for the treatment of a variety of disorders including tumors, Alzheimer...		Others
T60098	MSC2504877	3-(4-(2-Hydroxypropan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(2H)-one	Others
	MSC2504877 is an inhibitor of tankyrase and enhances the effects of clinical CDK4/6 inhibitors. MSC2504877 suppresses the upregulation of Cyclin D2 and Cyclin E2 caused by palbociclib and enhances the suppression of phos...		Others
T9315	MTOR kinase Inhibitor 2		Others
	2H-Imidazo[4,5-b]pyrazin-2-one, 1,3-dihydro-6-[6-(1-hydroxy-1-methylethyl)-3-pyridinyl]-1-[(tetrahydro-2H-pyran-4-yl)methyl]- is a potent mTOR inhibitor with IC50 of 0.176 μM and >30 μM for mTOR and PI3Kα, respectively.		Others
T38442	17,17-(Ethylenedioxy)androst-4-en-3-one		Others
	17,17-(Ethylenedioxy)androst-4-en-3-one (4- androstene- 3, 17- dione- 17- cyclic ethylene ketal) is an effective ingredient in cosmetics, which can be used for acne and promote hair growth research. 17,17-(Ethylenedioxy)...		Others
T22851	ICI 63197	2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one	PDE
	ICI 63197 (2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one) is a PDE4 inhibitor.		PDE
T36912	17α,20β-Dihydroxy-4-pregnen-3-one	17α,20β-dihydroxy Progesterone,17α,20β-DHP,17α,20β-Dihydroxy-4-pregnen-3-one	Others
	17α,20β-Dihydroxy-4-pregnen-3-one (17α,20β-DHP) is an endogenous, maturation-inducing steroid that stimulates oocyte maturation in females of several teleost species. For example, 1 μg/ml of 17α,20β-DHP applied to Persia...		Others
T9017	HPK1-IN-2	Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2,HPK1-IN-2	Others , FLT , Src
	HPK1-IN-2 (Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2) is a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1; IC50<0.05 μΜ). It also...		Others , FLT , Src
T50101	Perilipin-1/5 Inhibitor 1		Others
	1-[4-(2,3-dihydro-1,4-benzodioxine-6-sulfonyl)piperazin-1-yl]-2-(6-methyl-1-benzofuran-3-yl)ethan-1-one Yes An organic structural unit.		Others
T8651	CAL-101	(S)-2-(1-(9H-Purin-6-ylamino)ethyl)-5-fluoro-3-phenylquinazolin-4(3H)-one,GS-1101,Idelalisib	PI3K
	CAL-101 (Idelalisib) is a selective inhibitor of p110δ(IC50 : 2.5 nM; in cell-free assays); shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than...		PI3K
T8746L	I-49 free base	Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-,I-49	Raf
	I-49 free base (Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-) is a novel benzylamino substituted pyridopyrimidinone as SOS1 inhibito...		Raf
T25150	BI-69A11	BI 69A11,(E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one	NF-κB , Akt
	BI-69A11 ((E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one) is a dual AKT and NFkB pathway inhibitor. It enhances the susceptibility of colon cancer cells to mda-7/IL-24-induce...		NF-κB , Akt
T50072	FLT3 kinase inhibitor 2HCl		Others
	3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride is used in the synthesis of various compounds.		Others
T36133	3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one)		Others
	3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) is a non-nucleotide inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; Ki = 50 μM).1,2 It also inhibits urease (IC50 = 84.53 μM for the...		Others
T35646	4-oxo-2-Nonenal	4-oxo-2-Nonenal,4-ONE	Others
	4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid and linoleic acid. [1] [2] It exhibits various biological activities such as cytotoxicity, ...		Others
T19206	β-Lactamase-IN-1	4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one,beta-lactamase-IN-1	Antibacterial
	β-Lactamase-IN-1 (4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one) is a β-Lactamase inhibitor and targets the infection of Neisseria gonorrhoeae.		Antibacterial
T84531	6β-hydroxy Testosterone	4-Androsten-6β,17β-diol-3-one	Others
	6β-Hydroxy Testosterone, primarily metabolized from testosterone by CYP3A4 and CYP3A5 enzymes, represents 75-80% of testosterone's metabolites. Both cytochrome P450 enzymes, induced by glucocorticoids and various xenobio...		Others
T84867	5-Demethoxynobiletin	2-(3,4-dimethoxyphenyl)-6,7,8-trimethoxychromen-4-one	Others
	5-Demethylnobiletin (2-(3,4-dimethoxyphenyl)-6,7,8-trimethoxychromen-4-one), a distinctive flavonoid present in citrus fruits, shows potential as a chemopreventive agent against human cancers.		Others
T72531	6-Fluoromevalonate	Tetrahydro-4-fluoromethyl-4-hydroxy-2H-pyran-2-one	Others
	6-Fluoromevalonate is a mevalonate-pyrophosphate decarboxylase inhibitor.		Others
T84403	4-Thiouracil	2-hydroxy-4-Mercaptopyrimidine,4-Thiopyrimidin-2-one,NSC 43288,4-TU	Others
	4-Thiouracil is a photoactivatable probe designated for site-specific applications in detecting RNA structures and nucleic acid-nucleic acid contacts. Upon illumination with ultraviolet light exceeding 300 nm and in the ...		Others
T9398	NSC 73150	NSC 97967	Others
	6-methyl-2-[2-[(E)-(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]hydraziny l]-1H-pyrimidin-4-one (NSC 73150) is a pyrimidine derivative with antitumor activity. Preclinical studies have shown that it inhibits the growth of a...		Others
T84408	4-oxo-2-Nonenal Alkyne	Click Tag™ 4-oxo-2-Nonenal Alkyne,Alkynyl 4-oxo-2-Nonenal,4-ONE Alkyne	Others
	4-Oxo-2-nonanal (4-ONE) is a lipid peroxidation product that actively modifies histidine and lysine residues in proteins, leading to protein cross-linking, and alters 2'-deoxyguanosine, indicating its role in mutagenesis...		Others
T4698	8-Fluoro-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one		Others
	8-Fluoro-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one serves as a pharmaceutical intermediate.		Others
T8795	Met-kinase-in-2	1,6-Naphthyridin-4(1H)-one, 5-[[3-fluoro-4-[[7-(2-hydroxy-2-methylpropoxy)-4-quinolinyl]oxy]phenyl]amino]-3-phenyl-	Others
	MET kinase-IN-2, a selective and potent MET kinase inhibitor, demonstrates oral bioavailability and exhibits an IC50 value of 7.4 nM. It also possesses antitumor activity[1].		Others
T60018	NSC 694621		Others
	NSC 694621 is a potent PCAF inhibitor with an IC 50 of 5.71 μM ( PCAF/H3 1-21 ). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells that has the potential to be the new anticancer agent[1].		Others
T22256	C-Kit-IN-5-1	3-(2-Aminoquinazolin-6-yl)-4-methyl-1-(4-(oxazol-2-yl)phenyl)pyridin-2(1H)-one,AMG-25,3-(2-aminoquinazolin-6-yl)-4-methyl-1-[4-(1,3-oxazol-2-yl)phenyl]pyridin-2-one	c-Kit
	c-Kit-IN-5-1 (AMG-25) is a novel selective and potent c-Kit inhibitor.		c-Kit
T28029	Methylisothiazolinone hydrochloride	N-Methylisothiazolin-3-one,MI,KB-838,Methylisothiazolinone HCl	Others
	Methylisothiazolinone is a powerful synthetic biocide and preservative.		Others
T8721	I-37	Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-6-(1-methylcyclopropyl)-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-	Raf
	I-37 (Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-6-(1-methylcyclopropyl)-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-) is a novel benzylamino substituted pyridopyrimidinone as SOS1 inhibitor.		Raf
T65647	4-Isobutylpyrrolidin-2-one		Others
	4-Isobutylpyrrolidin-2-one is a useful organic compound for research related to life sciences. The catalog number is T65647 and the CAS number is 61312-87-6.		Others

Compounds

8-CHLOROQUINAZOLIN-4(1H)-ONE

T8619

Synonym:

Target: Others

1-(4-FLUORO-PHENYL)-BUTAN-1-ONE

T3679

Synonym:

Target: Others

1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one

T8601

Synonym: 4H-Indol-4-one, 2-ethyl-1,5,6,7-tetrahydro-1-(phenylmethyl)-

Target: Epigenetic Reader Domain

2-methyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one

T50014

Synonym:

Target: Epigenetic Reader Domain

6-ethyl-7-hydroxy-4-methylchromen-2-one

T4204

Synonym: 6-ethyl-7-hydroxy-4-methylcoumarin

Target: Others

2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one

T8563

Synonym:

Target: Serine Protease

SU 4981

T60094

Synonym: 3-(4-Morpholinobenzylidene)indolin-2-one

Target: VEGFR, Tyrosine Kinases

4-(3-Chlorophenyl)-2(3H)-thiazolone

T50012

Synonym: 4-(3-chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one

(3Z)-1-methyl-3-[2-(4-methylphenyl)-2-oxo-ethylidene]piperazin-2-one

Synonym: 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one

Target: Others

5-LOX inhibitor

T65427

Synonym: 1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one

Target: Lipoxygenase

Ceranib-2

T10761

Synonym: 3-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]-4-phenyl-1H-quinolin-2-one

Target: Apoptosis, S1P Receptor

Compound 401

T3586

Synonym: 2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one

Target: DNA-PK

CHEMBL241987

T8598

Synonym: 2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE

Target: Adenosine Receptor

1-Methylcytosine

T10019

Synonym: 1-methylcytosin,4-amino-1-methylpyrimidin-2(1H)-one,N-Methylcytosine

Target: Nucleoside Antimetabolite/Analog

Bragsin2

T14775

Synonym: 6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one,Bragsin 2

Target: Others

GSK-3β inhibitor 14

T67856

Synonym: 1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)-

Target: GSK-3

Riamilovir

T8904

Synonym: Triazavirin,7-methylsulfanyl-3-nitro-6H-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-one

Target: Antiviral

ACHE-IN-38

T80671

Synonym: 5,6-Dimethoxy-2-(piperidin-4-yl)methylene-indan-1-one

Target: Antifungal

Germinone A

T9007

Synonym: 3-Methyl-5-((3-nitro-[1,1'-biphenyl]-4-yl)oxy)furan-2(5H)-one

Target: Others

TCS PrP Inhibitor 13

T23450

Synonym: 5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One

Target: Others

3-(2,6-dichlorophenyl)-1-methyl-7-(methylsulfanyl)-1H,2H,3H,4H-pyrimido[4,5-d][1,3]diazin-4-one

Synonym: 3-(4-(2-Hydroxypropan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(2H)-one

Target: Others

mTOR kinase Inhibitor 2

T9315

Synonym:

Target: Others

17,17-(Ethylenedioxy)androst-4-en-3-one

Synonym: 2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one

Target: PDE

17α,20β-Dihydroxy-4-pregnen-3-one

T36912

Synonym: 17α,20β-dihydroxy Progesterone,17α,20β-DHP,17α,20β-Dihydroxy-4-pregnen-3-one

Target: Others

HPK1-IN-2

T9017

Synonym: Thieno[2,3-b]pyridin-6(7H)-one, 4-amino-5-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-HPK1-IN-2,HPK1-IN-2

Target: Others, FLT, Src

Perilipin-1/5 Inhibitor 1

Synonym: (S)-2-(1-(9H-Purin-6-ylamino)ethyl)-5-fluoro-3-phenylquinazolin-4(3H)-one,GS-1101,Idelalisib

Target: PI3K

I-49 free base

T8746L

Synonym: Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-,I-49

Target: Raf

BI-69A11

T25150

Synonym: BI 69A11,(E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one

Target: NF-κB, Akt

FLT3 kinase inhibitor 2HCl

T50072

Synonym:

Target: Others

3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one)

Synonym: 4-oxo-2-Nonenal,4-ONE

Target: Others

β-Lactamase-IN-1

T19206

Synonym: 4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one,beta-lactamase-IN-1

Target: Antibacterial

6β-hydroxy Testosterone

T84531

Synonym: 4-Androsten-6β,17β-diol-3-one

Target: Others

5-Demethoxynobiletin

T84867

Synonym: 2-(3,4-dimethoxyphenyl)-6,7,8-trimethoxychromen-4-one

Target: Others

6-Fluoromevalonate

T72531

Synonym: Tetrahydro-4-fluoromethyl-4-hydroxy-2H-pyran-2-one

Target: Others

4-Thiouracil

T84403

Synonym: 2-hydroxy-4-Mercaptopyrimidine,4-Thiopyrimidin-2-one,NSC 43288,4-TU

4-oxo-2-Nonenal Alkyne

T84408

Synonym: Click Tag™ 4-oxo-2-Nonenal Alkyne,Alkynyl 4-oxo-2-Nonenal,4-ONE Alkyne

Target: Others

8-Fluoro-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one

Synonym: 1,6-Naphthyridin-4(1H)-one, 5-[[3-fluoro-4-[[7-(2-hydroxy-2-methylpropoxy)-4-quinolinyl]oxy]phenyl]amino]-3-phenyl-

Synonym: 3-(2-Aminoquinazolin-6-yl)-4-methyl-1-(4-(oxazol-2-yl)phenyl)pyridin-2(1H)-one,AMG-25,3-(2-aminoquinazolin-6-yl)-4-methyl-1-[4-(1,3-oxazol-2-yl)phenyl]pyridin-2-one

Target: c-Kit

Methylisothiazolinone hydrochloride

T28029

Synonym: N-Methylisothiazolin-3-one,MI,KB-838,Methylisothiazolinone HCl

Target: Others

I-37

T8721

Synonym: Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-6-(1-methylcyclopropyl)-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-

Target: Raf

4-Isobutylpyrrolidin-2-one

T65647

Synonym:

Target: Others

カタログ番号	製品名	別名	ターゲット
T10196	7α-Hydroxy-4-cholesten-3-one		Others
			Others
TN7139	(3E)-4-(1H-indol-3-yl)but-3-en-2-one	4-(1H-indol-3-yl)but-3-en-2-one,(E)-4-(1H-indol-3-yl)but-3-en-2-one	Others
	(3E)-4-(1H-indol-3-yl)but-3-en-2-one ((E)-4-(1H-indol-3-yl)but-3-en-2-one) is a marine derived natural products found in Tedania (Tedania) ignis.		Others
T7345	7-Hydroxy-4H-chromen-4-one	7-hydroxy-4-benzopyrone,7-Hydroxy-4-chromone,7-Hydroxychromone	Src
	7-Hydroxy-4H-chromen-4-one (7-hydroxy-4-benzopyrone) is a Src kinase inhibitor (IC50 of <300 μM).		Src
TN5924	3-Hydroxy-1-(4-hydroxyphenyl)propan-1-one	3-Hydroxy-1-(4-hydroxyphenyl)-1-propanone	Others
	3-Hydroxy-1-(4-hydroxyphenyl)propan-1-one (3-Hydroxy-1-(4-hydroxyphenyl)-1-propanone) is a natural product derived from plant source.		Others
T19713	HHQ	2-heptylquinolin-4(1H)-one	Others
	HHQ (2-heptylquinolin-4(1H)-one) is a PqsR antagonist.		Others
T38375	Pseudane IX	2-nonyl-4-hydroxyquinoline,2-nonyl-1H-quinolin-4-one,2-nonyl-4(1h)-quinolone	HCV Protease
	Pseudane IX (2-nonyl-1H-quinolin-4-one) reduces infection of Huh 7.5 cells by hepatitis C virus (HCV) with an IC50 of 1.4 μg/ml.		HCV Protease
TN7125	2-Propen-1-one, 1-(2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-		Others
	2-Propen-1-one, 1-(2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)- can be used in studies about the inhibition against L-phenylalanine ammonia-lyase.		Others
T5240	Cholestenone	(+)-4-Cholesten-3-one	Others , Endogenous Metabolite
	Cholestenone is an intermediate oxidation product of cholesterol that is metabolized primarily in the liver. It can cause long-term defects in cell function. It is highly mobile in membranes and affects cholesterol turno...		Others , Endogenous Metabolite
TL0015	Pyromeconic acid	3-hydroxy-4H-pyran-4-one	Anti-infection
	Pyromeconic acid (3-hydroxy-4H-pyran-4-one) and derivatives thereof are potent inhibitors of endonuclease		Anti-infection
T0530	Flavanone	2-Phenyl-4-chromanone,4-Flavanone,2,3-Dihydroflavone,2-Phenylchroman-4-one	Others , Aromatase
	Flavanone (2-Phenylchroman-4-one)s from citrus fruits have also been shown to exert beneficial effects on human vascular function. In particular, chronic interventions with orange juice, or the pure flavanone hesperidin,...		Others , Aromatase
TN7133	4-Hydroxy-5-methyl-3-furanone	4-Hydroxy-5-methylfuran-3(2H)-one	Others
	4-Hydroxy-5-methyl-3-furanone (4-Hydroxy-5-methylfuran-3(2H)-one) is a natural product isolated from Eurycotis floridana.		Others
T33817	Orellanine	2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-one	Others
	Orellanine is a nephrotoxic compound extracted from the mushroom Cortinarius orellanus. Orellanine strongly inhibits the synthesis of macromolecules (Proteins, RNA and DNA) in Madin-Darby canine kidney cells and in rat l...		Others
T3343	5-methoxyflavone	5-methoxy-2-phenylchromen-4-one	DNA/RNA Synthesis
	5-methoxyflavone (5-methoxy-2-phenylchromen-4-one) is a naturally occurring, low molecular weight flavonoids compound that associated with a wide wariety of biological activities.		DNA/RNA Synthesis
TCS1709	BENZYLACETONE	4-Phenylbutan-2-one,Methyl 2-phenylethyl ketone,4-Phenyl-2-butanone	Tyrosinase
	Benzylacetone (4-Phenyl-2-butanone) is an aromatic compound extracted from incense wood. Benzylacetone has appetite-enhancing and exercise-reducing properties. Benzylacetone has a strong and reversible anti-mushroom tyro...		Tyrosinase
TN7157	(+/-)-Longamide	Pyrrolo[1,2-a]pyrazin-1(2H)-one, 6,7-dibromo-3,4-dihydro-4-hydroxy-,6,7-dibromo-4-hydroxy-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one,6,7-dibromo-4-hydroxy-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazin-1-one	Others
	(+/-)-Longamide (6,7-dibromo-4-hydroxy-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazin-1-one) is a marine derived natural products found in Sponge Homaxinella sp.		Others
T5548	Verbenone	2-Pinen-4-one,(-)-Verbenone	Others
	(-)-Verbenone is a naturally occurring terpene found in the leaves of Suregada zanzibariensis Verdc.Verbenone has anti-aggregation pheromone effects and interrupts the attraction of bark beetles to its aggregation pherom...		Others
TJS0368	4-Phenyl-7,8-dihydroxycoumarin	7,8-Dihydroxy-4-Phenyl-2H-Chromen-2-One,7,8-Dihydroxy-4-phenylcoumarin	Others
	4-Phenyl-7,8-dihydroxycoumarin (7,8-Dihydroxy-4-phenylcoumarin) inhibits the activity of Staphylococcus aureus DNA helicase		Others
TN1517	1-(2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one	Cochinchinenin A	Others
	1-(2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one (Cochinchinenin A) is the material basis for the analgesic effect of Dragons Blood.		Others
TJS0314	5,7-Dihydroxy-4-methylcoumarin	Methyl-2H-Chromen-2-One,4-Methyllimetol,4-Methyl-5,7-Dihydroxycoumarin	Others , Antibacterial , Antifungal
	5,7-Dihydroxy-4-methylcoumarin (Methyl-2H-Chromen-2-One) inhibits human neutrophil oxidative metabolism and elastase activity. 5,7-Dihydroxy-4-methylcoumarin has in vitro platelet antiaggregatory property. 5,7-Dihydroxy-...		Others , Antibacterial , Antifungal
TN7210	Pseudane V	2-pentylquinolin-4-ol,Compound Z1509149676,2-n-pentyl-4-quinolinol,2-Pentylquinolin-4(1H)-one	Others
	Pseudane V (2-pentylquinolin-4-ol) is a marine derived natural products found in Pseudoalteromonas sp. M2.		Others
TJS0328	Nordalbergin	6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One	Others
	Nordalbergin is a coumarin isolated from the bark of Dalbergia sissoo. It significantly induces differentiation of HL-60 cells.		Others
T5728	OsMundacetone	4-(3,4-Dihydroxyphenyl)-3-buten-2-one	Apoptosis , Reactive Oxygen Species
	OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) is a natual product isolated from Rhizoma osmundae.		Apoptosis , Reactive Oxygen Species
T4832	Cytosine	6-Aminopyrimidin-2(1H)-one,4-Amino-2-hydroxypyrimidine,Cytosinimine	Endogenous Metabolite
	Cytosine (6-Aminopyrimidin-2(1H)-one) is a pyrimidine base that is a fundamental unit of nucleic acids. The deamination of cytosine alone is apparent and the nucleotide of cytosine is the prime mutagenic nucleotide in le...		Endogenous Metabolite
TJS0318	6-Hydroxy-4-methylcoumarin	6-Hydroxy-4-Methyl-2H-Chromen-2-One	Others
	6-Hydroxy-4-methylcoumarin (6-Hydroxy-4-Methyl-2H-Chromen-2-One) is a secondary metabolite of coumarin, which has anticancer effects.		Others
TN7148	Mukanadin C	7-bromo-4-hydroxy-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one	Others
	Mukanadin C (7-bromo-4-hydroxy-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one) is a marine derived natural products found in Stylissa carteri.		Others
T5566	Ethyl maltol	2-Ethyl-3-hydroxy-4H-pyran-4-one,2-Ethyl pyromeconic acid	Others
	Ethyl maltol (2-Ethyl-3-hydroxy-4H-pyran-4-one) is an extract from medicinal plants such as P. Incarnata and can be used as an anticonvulsant. It is also a common flavoring.		Others
T12796	S-Dihydrodaidzein	(3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one	Others
	S-Dihydrodaidzein ((3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one) is an enantiomer of dihydrodaidzein which is involved in equol biosynthesis in a lactic acid bacterium, Lactococcus sp. strain.		Others
TN6788	5-hydroxy-3,7-dimethoxy-2-phenylchromen-	3,7-Dimethylgalangin,5-hydroxy-3,7-dimethoxy-2-phenylchromen-4-one,Galangin 3,7-dimethyl ether,4H-1-Benzopyran-4-one, 5-hydroxy-3,7-dimethoxy-2-phenyl-	Others
	5-hydroxy-3,7-dimethoxy-2-phenylchromen- (4H-1-Benzopyran-4-one, 5-hydroxy-3,7-dimethoxy-2-phenyl-),a natural product obtained from the resinous exudate of Heliotropium huascoense.		Others
TN5677	2,5-Dimethylchroman-4-one
	2,5-Dimethylchroman-4-one is a natural product for research related to life sciences. The catalog number is TN5677 and the CAS number is 69687-87-2.
TN7067	3',5-Di-O-methyl quercetin	3,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-5-methoxy-4H-chromen-4-one	Others
	3',5-Di-O-methyl quercetin (3,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-5-methoxy-4H-chromen-4-one) is a flavonoid natural product.		Others
T5S1805	5,7-Dihydroxychromone	5,7-Dihydroxy-4H-Chromen-4-One	Others , Virus Protease , PARP , Caspase , Nrf2
	1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect agai...		Others , Virus Protease , PARP , Caspase , Nrf2
TN6705	Graveoline	2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one,Foliosine	Autophagy
	Graveoline (2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one) is an apoptosis and autophagy inducer in skin melanoma cancer cells		Autophagy
TN3172	6beta-Hydroxystigmast-4-en-3-one		Others
	6beta-Hydroxystigmast-4-en-3-one is a natural product for research related to life sciences. The catalog number is TN3172 and the CAS number is 36450-02-9.		Others
TN3280	8-Hydroxy-4-cadinen-3-one		Others
	8-Hydroxy-4-cadinen-3-one shows significant inhibitory activity against A.thaliana seedling root growth.		Others
TN2758	2-Ethyl-2,6,6-trimethylpiperidin-4-one		Others
	2-Ethyl-2,6,6-trimethylpiperidin-4-one is a natural product for research related to life sciences. The catalog number is TN2758 and the CAS number is 133568-79-3.		Others
TQ0273	Neopterin	D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one	Endogenous Metabolite
	D-(+)-Neopterin (D-(+)-Neopterin) is produced by human monocytes/macrophages upon stimulation with the cytokine interferon-γ. In humans, neopterin is involved in purine biosynthesis.		Endogenous Metabolite
TN2917	3-Acetoxy-4-cadinen-8-one		Others
	3-Acetoxy-4-cadinen-8-one is a natural product for research related to life sciences. The catalog number is TN2917 and the CAS number is 923950-05-4.		Others
TN2522	1,7-Diphenyl-4-hepten-3-one		Others
	1,7-Diphenyl-4-hepten-3-one has feeding deterrent activities against Tribolium castaneum.		Others
TMA0098	3-Chloro-4-hydroxypiperidin-2-one		Others
	3-Chloro-4-hydroxypiperidin-2-one is a natural product for research related to life sciences. The catalog number is TMA0098 and the CAS number is 174204-83-2.		Others
TN2541	1-Hydroxybisabola-2,10-dien-4-one		Others
	1-Hydroxybisabola-2,10-dien-4-one has a wide range of applications in life science related research.		Others
TN3047	4-Methoxy-1-methylquinolin-2-one		Others
	4-Methoxy-1-methylquinolin-2-one is a natural product from Zanthoxylum nitidum.		Others
TN3153	6-Acetyl-2,2-dimethylchroman-4-one		PAFR
	6-Acetyl-2,2-dimethylchroman-4-one and vanillin show anti-platelet aggregation activity induced by arachidonic acid in vitro.		PAFR
TN3229	7-Hydroxy-3-(4-hydroxybenzylidene)chroman-4-one		Others
	7-Hydroxy-3-(4'-hydroxybenzylidene)-chroman-4-one may have anti-inflammatory activity.		Others
TN2552	1-Methyl-2-nonylquinolin-4(1H)-one		Others
	1-Methyl-2-nonylquinolin-4(1H)-one has anti-inflammatory activity, it exhibits inhibitory activity on leukotriene biosynthesis in a bioassay using human polymorphonuclear granulocytes, with IC50 values of 12.1 microM.		Others
TN5263	1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one	Xanthohumol	Apoptosis , BCL , PARP , HCV Protease , IAP , Caspase , HIV Protease , NMDAR , p53
	1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one (Xanthohumol) , prenylchacone flavonoid, is a natural product with multi-biofunctions purified from Hops Humulus lupulus,is e...
TN3218	7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one		Beta Amyloid , PI3K , mTOR
	7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one as a beneficial compound to ameliorate the deleterious effects of Aβ on dendrite integrity and cell survival, and may provide new insights on drug discovery of Alzheimer's dise...		Beta Amyloid , PI3K , mTOR
TN6985	Anhydronotoptol		NO Synthase
	Anhydronotoptol (4-{[(2E,5E)-3,7-dimethylocta-2,5,7-trien-1-yl]oxy}-7H-furo[3,2-g]chromen-7-one), a natural compound extracted from the umbelliferae plant Qiangwu, is a potent inhibitor of nitric oxide production, inhibi...		NO Synthase
TN2491	1,3-dihydroxy-4-methoxy-10-methylacridin-9-one	1,3-Dihydroxy-4-methoxy-10-methylacridin-9(10H)-one	Others
	1,3-dihydroxy-4-methoxy-10-methylacridin-9-one is a natural product for research related to life sciences. The catalog number is TN2491 and the CAS number is 1189362-86-4.		Others
TN5443	Kaempferol 3,4',7-triacetate	Kaempferol 3,4,7-triacetate,3,7-Bis(acetyloxy)-2-[4-(acetyloxy)phenyl]-5-hydroxy-4H-1-benzopyran-4-one,3,7,4'-Tri-O-acetylkaempferol,[4-(3,7-diacetyloxy-5-hydroxy-4-oxochromen-2-yl)phenyl] acetate	Others
	Kaempferol 3,4',7-triacetate (3,7,4'-Tri-O-acetylkaempferol) is a natural product of the herbs of Cudrania tricuspidata.		Others
TN5398	2-Cyclohexen-1-one, 5-(1,5-dimethyl-4-hexen-1-yl)-4-hydroxy-2-methyl-
	1-Hydroxybisabola-2,10-dien-4-one is a natural product for research related to life sciences. The catalog number is TN5398 and the CAS number is 124898-71-1.
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天然物製品

7α-Hydroxy-4-cholesten-3-one

T10196

Synonym:

Target: Others

(3E)-4-(1H-indol-3-yl)but-3-en-2-one

TN7139

Synonym: 4-(1H-indol-3-yl)but-3-en-2-one,(E)-4-(1H-indol-3-yl)but-3-en-2-one

Target: Others

7-Hydroxy-4H-chromen-4-one

T7345

Synonym: 7-hydroxy-4-benzopyrone,7-Hydroxy-4-chromone,7-Hydroxychromone

Target: Src

3-Hydroxy-1-(4-hydroxyphenyl)propan-1-one

TN5924

Synonym: 3-Hydroxy-1-(4-hydroxyphenyl)-1-propanone

Target: Others

HHQ

T19713

Synonym: 2-heptylquinolin-4(1H)-one

Target: Others

Pseudane IX

T38375

Synonym: 2-nonyl-4-hydroxyquinoline,2-nonyl-1H-quinolin-4-one,2-nonyl-4(1h)-quinolone

Target: HCV Protease

2-Propen-1-one, 1-(2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-

Synonym: (+)-4-Cholesten-3-one

Target: Others, Endogenous Metabolite

Pyromeconic acid

TL0015

Synonym: 3-hydroxy-4H-pyran-4-one

Target: Anti-infection

Flavanone

T0530

Synonym: 2-Phenyl-4-chromanone,4-Flavanone,2,3-Dihydroflavone,2-Phenylchroman-4-one

Target: Others, Aromatase

4-Hydroxy-5-methyl-3-furanone

TN7133

Synonym: 4-Hydroxy-5-methylfuran-3(2H)-one

Target: Others

Orellanine

T33817

Synonym: 2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-one

Target: Others

5-methoxyflavone

T3343

Synonym: 5-methoxy-2-phenylchromen-4-one

Target: DNA/RNA Synthesis

BENZYLACETONE

TCS1709

Synonym: 4-Phenylbutan-2-one,Methyl 2-phenylethyl ketone,4-Phenyl-2-butanone

Target: Tyrosinase

(+/-)-Longamide

TN7157

Synonym: Pyrrolo[1,2-a]pyrazin-1(2H)-one, 6,7-dibromo-3,4-dihydro-4-hydroxy-,6,7-dibromo-4-hydroxy-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one,6,7-dibromo-4-hydroxy-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazin-1-one

Target: Others

Verbenone

T5548

Synonym: 2-Pinen-4-one,(-)-Verbenone

Target: Others

4-Phenyl-7,8-dihydroxycoumarin

TJS0368

Synonym: 7,8-Dihydroxy-4-Phenyl-2H-Chromen-2-One,7,8-Dihydroxy-4-phenylcoumarin

Target: Others

1-(2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one

TN1517

Synonym: Cochinchinenin A

Target: Others

5,7-Dihydroxy-4-methylcoumarin

TJS0314

Synonym: Methyl-2H-Chromen-2-One,4-Methyllimetol,4-Methyl-5,7-Dihydroxycoumarin

Target: Others, Antibacterial, Antifungal

Pseudane V

TN7210

Synonym: 2-pentylquinolin-4-ol,Compound Z1509149676,2-n-pentyl-4-quinolinol,2-Pentylquinolin-4(1H)-one

Target: Others

Nordalbergin

TJS0328

Synonym: 6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One

Target: Others

OsMundacetone

T5728

Synonym: 4-(3,4-Dihydroxyphenyl)-3-buten-2-one

Target: Apoptosis, Reactive Oxygen Species

Cytosine

T4832

Synonym: 6-Aminopyrimidin-2(1H)-one,4-Amino-2-hydroxypyrimidine,Cytosinimine

Target: Endogenous Metabolite

6-Hydroxy-4-methylcoumarin

TJS0318

Synonym: 6-Hydroxy-4-Methyl-2H-Chromen-2-One

Target: Others

Mukanadin C

TN7148

Synonym: 7-bromo-4-hydroxy-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one

Target: Others

Ethyl maltol

T5566

Synonym: 2-Ethyl-3-hydroxy-4H-pyran-4-one,2-Ethyl pyromeconic acid

Target: Others

S-Dihydrodaidzein

T12796

Synonym: (3S)-7-hydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one

Target: Others

5-hydroxy-3,7-dimethoxy-2-phenylchromen-

TN6788

Synonym: 3,7-Dimethylgalangin,5-hydroxy-3,7-dimethoxy-2-phenylchromen-4-one,Galangin 3,7-dimethyl ether,4H-1-Benzopyran-4-one, 5-hydroxy-3,7-dimethoxy-2-phenyl-

Target: Others

2,5-Dimethylchroman-4-one

TN5677

Synonym:

Target:

3',5-Di-O-methyl quercetin

TN7067

Synonym: 3,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-5-methoxy-4H-chromen-4-one

Target: Others

5,7-Dihydroxychromone

T5S1805

Synonym: 5,7-Dihydroxy-4H-Chromen-4-One

Target: Others, Virus Protease, PARP, Caspase, Nrf2

Graveoline

TN6705

Synonym: 2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one,Foliosine

Target: Autophagy

6beta-Hydroxystigmast-4-en-3-one

TN3172

Synonym:

Target: Others

8-Hydroxy-4-cadinen-3-one

TN3280

Synonym:

Target: Others

2-Ethyl-2,6,6-trimethylpiperidin-4-one

Synonym: D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one

Target: Endogenous Metabolite

3-Acetoxy-4-cadinen-8-one

TN2917

Synonym:

Target: Others

1,7-Diphenyl-4-hepten-3-one

TN2522

Synonym:

Target: Others

3-Chloro-4-hydroxypiperidin-2-one

TMA0098

Synonym:

Target: Others

1-Hydroxybisabola-2,10-dien-4-one

TN2541

Synonym:

Target: Others

4-Methoxy-1-methylquinolin-2-one

TN3047

Synonym:

Target: Others

6-Acetyl-2,2-dimethylchroman-4-one

TN3153

Synonym:

Target: PAFR

7-Hydroxy-3-(4-hydroxybenzylidene)chroman-4-one

TN3229

Synonym:

Target: Others

1-Methyl-2-nonylquinolin-4(1H)-one

TN2552

Synonym:

Target: Others

1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one

TN5263

Synonym: Xanthohumol

Target: Apoptosis, BCL, PARP, HCV Protease, IAP, Caspase, HIV Protease, NMDAR, p53

7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one

TN3218

Synonym:

Target: Beta Amyloid, PI3K, mTOR

1,3-dihydroxy-4-methoxy-10-methylacridin-9-one

TN2491

Synonym: 1,3-Dihydroxy-4-methoxy-10-methylacridin-9(10H)-one

Target: Others

Kaempferol 3,4',7-triacetate

TN5443

Synonym: Kaempferol 3,4,7-triacetate,3,7-Bis(acetyloxy)-2-[4-(acetyloxy)phenyl]-5-hydroxy-4H-1-benzopyran-4-one,3,7,4'-Tri-O-acetylkaempferol,[4-(3,7-diacetyloxy-5-hydroxy-4-oxochromen-2-yl)phenyl] acetate

Target: Others

2-Cyclohexen-1-one, 5-(1,5-dimethyl-4-hexen-1-yl)-4-hydroxy-2-methyl-

TN5398

Synonym:

Target:

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-01406	MOB4 Protein, Human, Recombinant (His)	Human	E. coli
	MOB-Like Protein Phocein is a member of the MOB1/Phocein Family. MOB-Like Protein Phocein is associated with membranes and the Golgi stacks. It is present in the cytosol, where it behaves as a protein complex. It has bee...
TMPY-04483	IRAK4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPJ-00864	VEGF165 Protein, Human, Recombinant	Human	HEK293 Cells
	Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator...
TMPJ-01349	SEMA4B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domai...
TMPJ-00773	TUBB4A Protein, Human, Recombinant (His)	Human	E. coli
	Tubulin Beta-4A Chain (TUBB4A) is a cytoplasmic peptide containing 444 amino acids. TUBB4A is a member of the Tubulin family. Tubulin is the major constituent of microtubules. Tubulin is a dimer composed of one alpha and...
TMPY-04911	VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated	Human,Cynomolgus	HEK293 Cells
	VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.1 kDa and the accession number is P15692-4.
TMPK-00823	VEGF165 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPY-00749	FGF-2 Protein, Human, Recombinant	Human	E. coli
	FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4.
TMPJ-01348	SEMA4B Protein, Human, Recombinant (hFc & His)	Human	HEK293 Cells
	Semaphorin-4B is a single-pass type I membrane protein. SEMA4B is a member of the semaphorin family. The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B ...
TMPY-00894	PAPP-A2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Pappalysin-2/PAPP-A2 is the second member of the pappalysin family of metzincin superfamily, of which PAPP-A is the first member. There is no homology between the prepro-peptides of PAPP-A and PAPP-A2, but 46% of the res...
TMPY-03507	PPC-DC Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	PPC-DC, also known as PPCDC, belongs to the HFCD (homo oligomeric flavin containing Cys decarboxylase) superfamily which takes a part in the biosynthesis of coenzyme A (CoA) from pantothenate (Vitamin B). Biosynthesis of...
TMPY-01268	SMYD3 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger...
TMPJ-01108	SMAD4 Protein, Human, Recombinant (His)	Human	E. coli
	SMAD Family Member 4 (SMAD4) is a cytoplasmic protein that belongs to the Dwarfin/SMAD family. SMAD4 contains one MH1 (MAD homology 1) domain and one MH2 (MAD homology 2) domain. It is the component of the heterotrimeric...
TMPJ-01155	PDCD4 Protein, Human, Recombinant (His)	Human	E. coli
	Programmed Cell Death Protein 4 (PDCD4) is a member of the PDCD4 family. PDCD4 and EIF4A1 form a heterotrimer. One molecule of PDCD4 binds two molecules of EIF4A1. PDCD4 takes part in apoptosis via inhibiting translation...
TMPY-03990	Profilin 4 Protein, Human, Recombinant (His)	Human	E. coli
	PFN4, also known as profilin 4, is a member of the profilin family. Profilin can be detected in all eukaryotic organisms. It plays an important role in the spatially and temporally controlled growth of actin microfilamen...
TMPJ-00844	ANXA8 Protein, Human, Recombinant	Human	E. coli
	Annexin A8 (ANXA8) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A8 contains 4 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats ...
TMPJ-01098	PRDX4 Protein, Human, Recombinant (His)	Human	E. coli
	Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alk...
TMPJ-00958	B7-1 Protein, Rabbit, Recombinant (His)	Rabbit	HEK293 Cells
	Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their recep...
TMPJ-01037	CXCR4 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	C-X-C chemokine receptor type 4 (CXCR4) is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. This receptor ...
TMPY-01900	Kallikrein 4/KLK4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Kallikrein-4, also known as Enamel matrix serine proteinase 1, Kallikrein-like protein 1, KLK-L1, Serine protease 17, KLK4, PRSS17, and EMSP1, is a secreted protein that belongs to the peptidase S1 family and Kallikrein ...
TMPJ-00654	LGALS8 Protein, Human, Recombinant	Human	E. coli
	The Galectin family of proteins, with specificity for Nacetyllactosaminecontaining glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs). They also poss...
TMPY-02453	CROT Protein, Human, Recombinant (474 Leu/Val, His)	Human	Baculovirus Insect Cells
	Carnitine octanoyltransferase (CROT or COT), also known as octanoyl-CoA: L-carnitine O-octanoyltransferase, medium-chain/long-chain carnitine acyltransferase, and carnitine medium-chain acyltransferase, is a carnitine ac...
TMPJ-00280	TNF R1 Protein, Mouse, Recombinant	Mouse	E. coli
	Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate t...
TMPJ-01373	DKK3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Dickkopf-related protein 3 (DKK3) belongs to the DKK protein family including Dkk-1, 2, 3 and -4. DKK3 is a 350 amino acid secreted glycoprotein which is comprised of an N-terminal signal peptide and 2 conserved cysteine...
TMPJ-00630	B7-1 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and...
TMPY-02001	RTN4 Protein, Human, Recombinant (GST)	Human	E. coli
	Reticulon-4, also known as Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5 and RTN4, is a multi-pass membrane protein that...
TMPJ-01036	Beta-Actin Protein, Human, Recombinant (His)	Human	E. coli
	Actins are ubiquitous globular and highly conserved proteins that are involved in various types of cell motility, structure, and integrity. Three main groups of actin isoforms, alpha, beta and gamma have been identified....
TMPY-01654	ITCH Protein, Human, Recombinant (aa 526-903)	Human	E. coli
	E3 ubiquitin-protein ligase Itchy homolog, also known as Atrophin-1-interacting protein 4, NFE2-associated polypeptide 1, NAPP1, and ITCH, is a cell membrane protein that contains one C2 domain, one HECT (E6AP-type E3 ub...
TMPJ-01385	CLEC4E Protein, Human, Recombinant (His)	Human	HEK293 Cells
	C-Type Lectin Domain Family 4 Member E (CLEC4E) is a 219 amino acid single-pass type II membrane protein that contains one C-type Lectin domain. It is expressed in monocytes, CLEC4E functions as a downstream target of C/...
TMPY-04557	PHKG1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform, also known as Phosphorylase kinase subunit gamma-1 and PHKG1, is a member of the protein kinase superfamily and CAMK Ser/Thr protein kinase family. P...
TMPY-04357	RSK4 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Ribosomal protein S6 kinase alpha-6, also known as Ribosomal S6 kinase 4, 9 kDa ribosomal protein S6 kinase 6,RSK-4, RSK4 and RPS6KA6, is a protein that belongs to the protein kinase superfamily, AGC Ser/Thr protein kina...
TMPY-00886	MMP-1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MMP1, also known as MMP-1, contains 4 hemopexin-like domains and is a member of the matrix metalloproteinase (MMP) family. Matrix metalloproteases, also called matrixins, are zinc-dependent endopeptidases that are the ma...
TMPY-01614	VNN2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Vascular non-inflammatory molecule 2, also known as glycosyl-phosphatidyl inositol-anchored protein GPI-8, Vanin-2, Protein FOAP-4 and VNN2, is a cell membrane protein that belongs to the CN hydrolase family and Vanin su...
TMPY-03612	PSME1 Protein, Human, Recombinant (His)	Human	E. coli
	PA28A, also known as PSME1, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed ...
TMPH-02539	MGAT3 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	It is involved in the regulation of the biosynthesis and biological function of glycoprotein oligosaccharides. Catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannos...
TMPY-01416	OLFM4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Olfactomedin-4, also known as G-CSF-stimulated clone 1 protein, Antiapoptotic protein GW112, and OLFM4, is a secreted protein that contains one olfactomedin-like domain. The OLFM4 gene was recently reported to inhibit va...
TMPY-03610	PSME2 Protein, Human, Recombinant (His)	Human	E. coli
	PSME2, also known as PA28b, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed ...
TMPY-04754	CASK Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	CASK Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 102.1 kDa and the accession number is O14936-4.
TMPY-01822	PTK9 Protein, Human, Recombinant (His & GST)	Human	E. coli
	PTK9 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 57 kDa and the accession number is Q12792-4.
TMPY-02893	NT5C3A/NT5C3 Protein, Human, Recombinant	Human	E. coli
	NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded prot...
TMPY-04471	APEG1 Protein, Human, Recombinant (His)	Human	E. coli
	Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr pr...
TMPK-00822	VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPK-00423	CD45 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPY-00380	ANTXR2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ANTXR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.4 kDa and the accession number is P58335-4.
TMPY-05598	Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 103.7 kDa and the accession number is P20273-4.
TMPY-01033	IL-32 Protein, Human, Recombinant (isoform alpha, His)	Human	HEK293 Cells
	IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathw...
TMPY-01117	MRAP Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain,...
TMPK-00424	CD45 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPJ-00410	CD45R0 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD45R0 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 80-120 KDa and the accession number is P08575-4.
TMPJ-00782	Amyloid Precursor Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and...
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